LXRX Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines

03
Prix $1.82
Capitalisation Boursière (MRQ) $813M
P/E (TTM) -12.1
BPA (TTM) $-0.15
Revenu (TTM) $41M
ROE (TTM) -40.2%
Dette/Capitaux propres (MRQ) 0.3
Fourchette 52 semaines $1–$3

LXRX Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue

04
fourchette
barres

La granularité des barres s'adapte à la période sélectionnée — survolez le graphique pour voir l'ouverture/le maximum/le minimum/la clôture d'une barre.

Splits d'actions 1
Date ex-dividende Division Type
21 mai 2015 1-for-7 Inverse

À propos de Lexicon Pharmaceuticals, Inc. - Common Stock Présentation de l'entreprise depuis Wikipedia

05 · wikidata

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

The company's clinical drug candidates include sotagliflozin (LX4211) for the treatment of type 2 diabetes; LX1033 for the treatment of irritable bowel syndrome and other gastrointestinal disorders; telotristat ethyl (LX1032) for the treatment of the symptoms associated with carcinoid syndrome; and LX2931 for the treatment of autoimmune diseases, such as rheumatoid arthritis.

Company history

Lexicon Pharmaceuticals was founded in September 1995 as a biotech venture of Baylor College of Medicine. The company went public in April 2000 with $220 million initial public offerings. In June, 2001 Lexicon purchased a privately owned small chemical library synthesis company, Coelacanth Corporation in Princeton, New Jersey, which became the site for the company's small molecule and medicinal chemistry efforts. The company's original name was Lexicon Genetics Incorporated, but in 2007, the name changed to Lexicon Pharmaceuticals, Inc. to reflect a renewed focus on drug development.

The company initially focused on using gene knockout technology to define the function of genes. This effort complemented and benefited from the international effort to sequence the human and mouse genomes (see Human Genome Project). Using its proprietary gene trapping and gene targeting technologies, the company created A repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale mammalian knockout program to discover the physiological and behavioral functions of the most druggable mammalian genes. The information collected from this program is stored in the company's LexVision database, which contains almost 5,000 gene knockouts studied. Over the years, Lexicon evolved from a genomics company into a drug discovery and development company focused on discovering and developing treatments for human disease. The company currently has multiple drug candidates in various stages of clinical trials.

In 2016, the company was ranked #8 on the Deloitte Fast 500 North America list.

Technology

Lexicon uses patented gene trapping and gene targeting technologies to generate and study knockout mice to discover the physiological and behavioral effects that result from the disruption of a single gene knockout. Because there is a close similarity in gene function and physiology between mice and humans, with a large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines.

The value of Lexicon's technology in drug discovery has been described in a retrospective analysis by the scientific journal Nature. The conclusion of this analysis was that, in most cases, there was a direct correlation when comparing the physiological characteristics, or phenotypes, of knockout mice to the therapeutic effect of the 100 best-selling drugs of 2001. The tremendous utility of knockout mouse technology was recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. Mario Capecchi, Martin Evans, and Oliver Smithies.

In developing small molecule drugs for its validated targets, Lexicon uses medicinal chemistry known as "click chemistry." Dr. K. Barry Sharpless, who was awarded the 2001 Nobel Prize in Chemistry, developed this tools for the rapid synthesis of novel compounds. Lexicon uses solution-phase chemistry to generate diverse libraries of optically pure compounds that are built using organic reactions that allow the company to generate collections of different compounds and to tailor the compound collections to address various therapeutic target families. Lexicon's medicinal chemists design these libraries by analyzing the chemical structures of drugs that have been proven safe and effective against human disease and using that knowledge in the design of scaffolds and chemical building blocks for the generation of large numbers of new drug-like compounds.

Locations

Lexicon operates from two locations found in Texas and New Jersey. The corporate headquarters are in The Woodlands, Texas just north of Houston. This location serves as Lexicon's primary research facility to discover and validate the company's drug targets and test drug candidates in preclinical research. The company's clinical development and regulatory team is also based at the corporate headquarters.

Lexicon's campus in Princeton, New Jersey is the home of Lexicon's small molecule medicinal chemistry and preclinical development efforts. This site serves as Lexicon's primary medicinal chemistry site to create new chemical entities for therapeutic development.

== References ==

Source : Wikipedia (Anglais), CC BY-SA 4.0 · Voir sur Wikipedia ↗

Wikidata ↗

secteurHealthcare industriePharmaceuticals employés81 paysUS

Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA

06
Revenu$50M
2016-12-31 → 2025-12-31
BPA$-0.14
2017-12-31 → 2025-12-31
Flux de trésorerie libre$-68M
2016-12-31 → 2025-12-31
Marge nette-147.4%
2016-12-31 → 2025-12-31
Valorisation et Ratios 07–12

Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?

Métrique Tendance sur 5 ans LXRX moyenne 5 ans Médiane des pairs Verdict
P/E (TTM) -12.1moyenne 5 ans ≈-4.2 ≈-4.2 · ·
P/S (TTM) 19.6moyenne 5 ans ≈1530.9 ≈1530.9 6.6 Surévalué
P/B (MRQ) 4.7moyenne 5 ans ≈4.1 ≈4.1 3.8 Surévalué
EV / EBITDA (TTM) -12.5 · · ·
Price / FCF (Cours / FCF) -9.8moyenne 5 ans ≈-5.6 ≈-5.6 · ·
Price / Cash Flow (Cours / Flux de trésorerie) -9.8moyenne 5 ans ≈-5.7 ≈-5.7 · ·
VE / Chiffre d'affaires (TTM) 16.3 · · ·
EV / FCF (VE / FCF) -9.2 · · ·
Price / Tangible Book (Cours / Actif net tangible) 10.6moyenne 5 ans ≈6.7 ≈6.7 · ·

La médiane des pairs est calculée sur une base standardisée par métrique et peut ne pas toujours correspondre à la base TTM/MRQ indiquée pour cette action.

valeur · ≈ moyenne 5 ans · médiane du secteur · verdict par rapport à la médiane

Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats

14
Surprise Moyenne 48.2%
Prochain rapport Nov 13, 2026
PériodeRapportEPS ActualBPA est.Surprise
30 juin 2026 Aoû 4, 2026 $-0.07 $-0.05 -36.7%
31 mars 2026 Mai 11, 2026 $0.00 $-0.04 100.0%
31 décembre 2025 $-0.04 $-0.07 43.2%
30 septembre 2025 $-0.04 $-0.07 40.6%
30 juin 2025 $0.01 $-0.08 112.6%
31 mars 2025 $-0.07 $-0.10 29.6%

Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie

15
Compte de résultat 16
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Cost of Revenue $274.0K$616.0K$85.0K$0$0$2M$3M$2M$2M$0$0·
R&D Expense $61M$84M$59M$53M$55M$154M$92M$100M$152M$164M$95M$89M
SG&A Expense $37M$143M$114M$48M$32M$47M$57M$64M$66M$43M$24M$19M
Operating Expenses $99M$228M$173M$101M$87M$204M$181M$166M$222M$206M$129M$123M
Operating Income $-49M$-197M$-172M$-101M$-87M$-48M$141M$-103M$-131M$-127M$1M$-100M
Interest Expense ···$3M$802.0K$15M$21M$21M$7M$7M$7M$2M
Other Non-op $7M$12M$8M$2M$134.0K$3M$3M$4M$2M$2M$572.0K$2M
Pretax Income ····$-88M$-59M$124M$-121M$-136M$-131M$-5M$-100M
Income Tax ·$0$0$0$0····$0$0$-70.0K
Net Income $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
EPS (Basic) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.23$-1.14$-1.17···
EPS (Diluted) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17···
Shares (Basic) 363,053,000320,031,000221,130,000165,733,000145,652,000·······
Shares (Diluted) 363,053,000320,031,000221,130,000165,733,000145,652,000110,841,000116,747,000105,830,000105,237,000···
EBITDA $-48M$-197M$-171M$-100M$-87M$-45M$145M$-100M$-133M$-135M·$-98M
Bilan 30
Métrique Tendance 202520242023202220212020201920182017201620152014
Cash & Equivalents $34M$67M$22M$46M$64M$126M$36M$80M$62M$47M$203M$137M
Short-term Investments $62M$171M$148M$92M$23M$26M$236M$80M$249M$300M$318M$202M
Receivables $2M$3M$1M$28.0K$14.0K$395.0K$57M$6M$5M$7M$911.0K$1M
Inventory $281.0K$231.0K$381.0K$0·$0$4M$5M$2M$0··
Other Current Assets $3M$5M$5M$2M$2M$5M$5M$3M$4M$4M$10M$5M
Current Assets $102M$246M$177M$141M$89M$158M$338M$173M$322M$358M$532M$369M
PP&E (Net) $2M$2M$2M$2M$1M$295.0K$14M$16M$18M$19M$21M$1M
PP&E (Gross) $5M$5M$7M$6M$6M$6M$76M$76M$76M$79M$81M$37M
Accum. Depreciation $3M$2M$5M$4M$5M$6M$62M$60M$59M$60M$59M$36M
Goodwill $45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M
Intangibles ······$20M$50M$52M$53M$53M$53M
Other Non-current Assets $368.0K$368.0K$828.0K$412.0K$2M$1M$2M$285.0K$429.0K$461.0K$433.0K$3M
Total Assets $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Accounts Payable $3M$15M$14M$10M$9M$5M$12M$12M$39M$53M$20M$13M
Accrued Liabilities $13M$30M$17M$13M$13M$30M$42M$21M$12M$32M$25M$10M
Current Liabilities $21M$45M$32M$23M$22M$47M$65M$37M$105M$165M$123M$45M
Capital Leases $7M$5M$5M$5M········
Deferred Tax ······$0$6M$6M$19M$19M$19M
Other Non-current Liabilities $7M$7M$5M$5M$1M$611.0K$1M$238.0K$292.0K$805.0K$14M$24M
Total Liabilities $77M$152M$136M$77M$23M$47M$301M$311M$368M$318M$366M$187M
Long-term Debt $54M$100M·$49M$0$12M$249M$250M$252M$101M$106M$108M
Total Debt $54M$100M$100M·$0$12M$245M$245M$246M$101M·$108M
Common Stock $366.0K$363.0K$245.0K$189.0K$150.0K$142.0K$106.0K$106.0K$106.0K$105.0K$104.0K$104.0K
Paid-in Capital $2.13B$2.12B$1.86B$1.71B$1.61B$1.56B$1.46B$1.45B$1.44B$1.41B$1.40B$1.39B
Retained Earnings $-2.02B$-1.97B$-1.77B$-1.59B$-1.49B$-1.40B$-1.34B$-1.47B$-1.37B$-1.25B$-1.11B$-1.10B
Treasury Stock $5M$5M$3M$2M$8M$5M$4M$3M$2M$3M$3M$2M
AOCI $30.0K$119.0K$31.0K$-428.0K$-10.0K$-6.0K$84.0K$-12.0K$-222.0K$-195.0K$-219.0K$-63.0K
Stockholders' Equity $108M$146M$93M$117M$114M$156M$117M$-26M$68M$168M$286M$284M
Liabilities + Equity $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Shares Outstanding 365,848,216363,020,303·189,214,000150,082,000142,289,000106,679,000106,162,000105,711,000104,582,000103,860,000103,663,000
Flux de trésorerie 17
Métrique Tendance 202520242023202220212020201920182017201620152014
D&A $621.0K$534.0K$554.0K$427.0K$292.0K$3M$4M$4M$3M$2M$727.0K$2M
Stock-based Comp $13M$13M$14M$12M$11M$13M$14M$12M$9M$7M$7M$7M
Deferred Tax ···$0$0$0$-6M$0$-13M$0$0$-70.0K
Amort. of Intangibles ·······$2M$2M···
Other Non-cash $-31M$8M$328.0K$1M$-10M$-101M$-28M$-43M$-57M$-44M·$16M
Operating Cash Flow $-68M$-179M$-162M$-89M$-87M$-143M$114M$-149M$-185M$-176M$185M$-76M
CapEx $0$1M$470.0K$1M$1M$87.0K$70.0K$95.0K$228.0K$231.0K$910.0K$80.0K
Investing Cash Flow $113M$-15M$-50M$-71M$2M$381M$-156M$170M$51M$18M$-117M$-108M
Debt Issued $0$0$50M$49M·$0$0$13M$146M$0$0$84M
Net Debt Issued $0$0·$49M$-12M$-217M$-1M$-2M$144M$-2M·$82M
Stock Issued $0$0$139M$94M$37M$70M$0$732.0K$8M$4M$114.0K$202M
Stock Repurchased ·$2M$824.0K$864.0K$3M$1M$941.0K$972.0K$2M$621.0K$357.0K$887.0K
Net Stock Activity $0$-2M$138M$93M$34M$69M$-941.0K$-240.0K$6M$3M·$201M
Financing Cash Flow $-48M$238M$188M$142M$23M$-148M$-2M$-2M$150M$987.0K$-2M$284M
Net Change in Cash $-3M$44M$-24M$-18M$-62M$90M$-44M$19M$15M$-156M$66M$100M
Free Cash Flow $-68M$-180M$-162M$-90M$-88M$-143M$114M$-149M$-186M$-176M·$-76M
Levered FCF ·········$-182M·$-78M
Rentabilité 7
Métrique Tendance 202520242023202220212020201920182017201620152014
Operating Margin -98.2%-634.2%-14264.9%-72489.2%-29224.8%-199.2%43.9%-163.4%-151.3%-164.6%·-439.2%
Net Margin -101.1%-644.8%-14710.9%-73341.0%-29449.0%-244.1%40.4%-190.7%-142.9%-169.7%·-438.8%
Pretax Margin ····-29449.0%-244.1%38.5%-190.7%-156.9%-169.7%·-439.1%
EBITDA Margin -97.0%-632.5%-14218.9%-72182.0%-29126.9%-187.0%45.1%-157.6%-147.5%-162.1%·-430.7%
ROA -20.8%-75.9%-83.6%-61.6%-51.5%-18.9%37.1%-33.5%-28.3%-25.1%·-26.9%
ROE -39.7%-167.7%-168.5%-88.4%-65.0%-42.8%287.0%-576.0%-117.5%-63.8%·-44.2%
ROIC ·········-53.0%·-25.6%
Liquidité et Solvabilité 5
Métrique Tendance 202520242023202220212020201920182017201620152014
Current Ratio 4.95.45.66.14.03.45.24.72.62.2·8.2
Quick Ratio 4.75.35.46.03.93.35.04.52.52.2·7.6
Debt / Equity 0.50.71.1·0.00.12.1-9.34.70.6·0.4
LT Debt / Equity 0.50.71.1··0.02.0-9.24.40.5·0.3
Interest Coverage ···-36.2-108.6-3.36.8-5.0-19.6-20.9·-44.5
Efficacité 3
Métrique Tendance 202520242023202220212020201920182017201620152014
Asset Turnover 0.20.10.00.00.00.10.90.20.20.1·0.1
Inventory Turnover 1.12.00.4··0.90.70.81.9···
Receivables Turnover 17.013.92.36.61.50.810.311.814.719.8·25.0
Par action 5
Métrique Tendance 202520242023202220212020201920182017201620152014
Book Value / Share $0.29··$0.62$0.76$1.10$1.10$-0.25$0.49$1.50·$0.39
Revenue / Share $0.14$0.10$0.01·$0.00$0.22$2.76·····
Cash Flow / Share $-0.19$-0.56$-0.73·$-0.60$-1.29$0.97·····
Cash / Share $0.09··$0.24$0.43$0.89$0.34$0.76$0.58$0.45·$0.19
EPS (TTM) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17$-0.12$-0.12·
Taux de croissance 3
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue YoY 60.2%2481.5%766.2%-53.4%-98.8%·······
Revenue CAGR 3Y 610.2%370.7%-63.1%·········
Revenue CAGR 5Y 15.7%···········
Valorisation (TTM) 14
Métrique Tendance 202520242023202220212020201920182017201620152014
Revenue TTM $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Net Income TTM $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
Market Cap $421M··$361M$591M$487M$443M$705M$1.04B$1.45B·$4.62B
Enterprise Value $378M···$505M$346M$416M$790M$979M$1.20B·$4.39B
P/E -8.2-1.2-1.9-3.1-6.6-6.53.6-5.8-8.4-115.2-110.9·
P/S 8.4··2600.01984.320.31.411.211.418.2·202.3
P/B 3.9··3.15.23.13.8-26.720.09.2·16.3
P / Tangible Book 6.7··5.08.64.4······
P / Cash Flow -6.2··-4.1-6.8-3.43.9-4.7-5.6-8.2·-61.1
P / FCF -6.2··-4.0-6.7-3.43.9-4.7-5.6-8.2·-61.1
EV / EBITDA -7.8···-5.8-7.72.9-7.9-7.3-8.9·-44.6
EV / FCF -5.6···-5.7-2.43.7-5.3-5.3-6.8·-58.0
EV / Revenue 7.6···1693.214.41.312.510.715.2·192.1
Earnings Yield -12.2%-85.1%-52.3%-32.5%-15.2%-15.5%28.0%-17.2%-11.8%-0.87%-0.90%·

Période la plus récente à gauche · valeurs nulles affichées comme ·

États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années

16
Métrique 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenu $50M $31M $1M $139.0K $298.0K
Marge d'exploitation % -98.2% -634.2% -14264.9% -72489.2% -29224.8%
Résultat net $-50M $-200M $-177M $-102M $-88M
BPA dilué $-0.14 $-0.63 $-0.80 $-0.62 $-0.60

Détenteurs institutionnels (13F) 167 déclarants · $890.0M total · Au 30 juin 2026

17

Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.

Détenteurs 167
Valeur détenue $890.0M
Nouvelles positions 43
Positions clôturées 27
Activité institutionnelle — Q2 2026 vs trimestre précédent
Nouvelles positions Positions clôturées Augmenté Diminué Variation nette des actions
43 (+9 vs T. préc.) 27 (+14 vs T. préc.) 39 (-5 vs T. préc.) 38 (+14 vs T. préc.) +42.4M

Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.

Institution Valeur Actions % de 13F suivies Type
Artal Group S.A. $420 374 549 175 156 062 47,23% Actions
FMR LLC $124 276 907 51 782 045 13,96% Actions
Siren, L.L.C. $106 328 443 44 303 518 11,95% Actions
Sessa Capital IM, L.P. $45 506 006 18 960 836 5,11% Actions
BlackRock, Inc. $41 636 978 17 348 741 4,68% Actions
VANGUARD CAPITAL MANAGEMENT LLC $23 762 899 9 901 208 2,67% Actions
Point72 Asset Management, L.P. $19 803 180 8 251 325 2,23% Actions
GEODE CAPITAL MANAGEMENT, LLC $14 989 739 6 244 372 1,68% Actions
STATE STREET CORP $11 802 646 4 917 769 1,33% Actions
VANGUARD GROUP INC $11 047 532 9 606 549 1,24% Actions
VANGUARD PORTFOLIO MANAGEMENT LLC $5 658 598 2 357 749 0,64% Actions
NORTHERN TRUST CORP $4 724 686 1 968 619 0,53% Actions
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4 696 260 1 956 775 0,53% Actions
VANGUARD FIDUCIARY TRUST CO $3 922 970 1 634 571 0,44% Actions
CITADEL ADVISORS LLC $3 842 837 1 601 182 0,43% Actions
CIBC Private Wealth Group LLC $3 240 347 2 400 257 0,36% Actions
Ishara Investments LP $3 050 400 1 271 000 0,34% Actions
MILLENNIUM MANAGEMENT LLC $2 722 150 1 134 229 0,31% Actions
RENAISSANCE TECHNOLOGIES LLC $2 704 800 1 127 000 0,30% Actions
MACKENZIE FINANCIAL CORP $2 312 050 963 354 0,26% Actions
ADAR1 Capital Management, LLC $1 800 000 750 000 0,20% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1 672 262 696 776 0,19% Actions
UBS Group AG $1 643 312 684 713 0,18% Actions
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1 604 400 668 500 0,18% Option d'achat
TWO SIGMA INVESTMENTS, LP $1 544 266 643 444 0,17% Actions
Nuveen, LLC $1 407 994 586 664 0,16% Actions
JANE STREET GROUP, LLC $1 398 960 582 900 0,16% Option d'achat
Bank of New York Mellon Corp $1 364 893 568 706 0,15% Actions
Invesco Ltd. $1 219 370 508 071 0,14% Actions
GOLDMAN SACHS GROUP INC $1 165 310 485 546 0,13% Actions
Compagnie Lombard Odier SCmA $1 152 000 480 000 0,13% Actions
BANK OF AMERICA CORP /DE/ $1 011 117 421 299 0,11% Actions
BARCLAYS PLC $929 960 387 483 0,10% Actions
CITADEL ADVISORS LLC $886 320 369 300 0,10% Option d'achat
XTX Topco Ltd $858 905 357 877 0,10% Actions
CANADA PENSION PLAN INVESTMENT BOARD $618 960 257 900 0,07% Actions
RHUMBLINE ADVISERS $616 523 256 885 0,07% Actions
DEUTSCHE BANK AG\ $594 068 247 528 0,07% Actions
WELLS FARGO & COMPANY/MN $553 128 230 470 0,06% Actions
WELLINGTON MANAGEMENT GROUP LLP $431 280 179 700 0,05% Actions
CITIGROUP INC $420 492 175 205 0,05% Actions
GROUP ONE TRADING LLC $420 031 175 013 0,05% Actions
Virtus Investment Advisers, LLC $408 996 170 415 0,05% Actions
Headlands Technologies LLC $401 275 167 198 0,05% Actions
Ikarian Capital, LLC $395 218 164 674 0,04% Actions
Quarry LP $374 846 156 186 0,04% Actions
MetLife Investment Management, LLC $351 384 146 410 0,04% Actions
MORGAN STANLEY $318 964 132 902 0,04% Actions
PANAGORA ASSET MANAGEMENT INC $316 901 132 042 0,04% Actions
JPMORGAN CHASE & CO $289 975 109 839 0,03% Actions

Afficher les 167 détenteurs institutionnels →

Activistes et détenteurs de 5%+ 11 participations

18

Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.

Déclarant Déposé Participation Statut Objectif Dépôt
Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Global Management, LLC, Siren, L.L.C., Avicenna Life Sci Master Fund LP, Avicenna Life Sci Master GP LLC, Invus US Partners LLC, Ulys, L.L.C., Raymond Debbane, Artal Participations S.a r.l., Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend, Amaury Wittouck ×7 dépôts 8 mai 2026 39,40% Amendement · SEC
Invus, L.P. (2), Invus Advisors, L.L.C. (2), Invus Public Equities, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Global Management, LLC (2), Siren, L.L.C. (2), Artal Participations S.à r.l. (2), Artal International S.C.A. (2), Artal International Management S.A. (2), Artal Group S.A. (2), Westend S.A. (2), Stichting Administratiekantoor Westend (2), Mr. Amaury Wittouck (2), Invus US Partners LLC (2), Ulys, L.L.C. (2), Mr. Raymond Debbane (2) ×15 dépôts 9 décembre 2024 · Dépôt initial · SEC
24 février 2012 · Dépôt initial · SEC
Raymond Debbane (2), Ulys, L.L.C. (2), Invus Advisors, L.L.C. (2), Invus, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Public Equities, L.P. (2), Invus C.V. (2) 27 décembre 2011 · Dépôt initial · SEC
14 novembre 2011 · Dépôt initial · SEC
15 août 2011 · Dépôt initial · SEC
Raymond Debbane, Ulys, L.L.C., Invus Advisors, L.L.C., Invus, L.P., Invus Public Equities Advisors, LLC, Invus Public Equities, L.P., Invus C.V. 19 mars 2010 · Dépôt initial Structure du capital SEC
Estate of Gordon A. Cain (, Mary H. Cain ×4 dépôts 5 août 2005 · Dépôt initial · SEC
Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée 8 août 2003 · Dépôt initial · SEC
Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée 18 juillet 2003 · Dépôt initial Investissement passif SEC
Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée 19 mars 2003 · Dépôt initial · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Initiés de la société 49 initiés · 32 dirigeants · 19 administrateurs

19
Dirigeant Rôle Dernière activité Actions détenues Achats 12m Ventes 12m Net 12m
Michael Exton Chief Executive Officer 28 février 2026 M 298 432 0 0 $0
Lonnel Coats Chief Executive Officer 28 février 2024 M 1 098 068 0 0 $0
Arthur T Sands President & CEO 28 février 2014 M 1 021 329 0 0 $0
Scott M Coiante SVP, Chief Financial Officer 28 février 2026 M 105 356 0 0 $0
Ajay Bansal EVP Corp Dev and CFO 2 juin 2009 A · 0 0 $0
Julia P Gregory EVP and CFO 7 février 2008 A 50 200 0 0 $0
Jeffrey L Wade President and COO 8 juillet 2024 A 324 214 0 0 $0
Rachel Yap Martens SVP, Partnerships & Corp Strat 28 février 2026 M 31 264 0 0 $0
Suma Gopinathan SVP, Discovery 28 février 2026 M 150 132 0 0 $0
Wendy Mcdermott SVP, Human Resources 28 février 2026 M 277 945 0 0 $0
Craig B Granowitz SVP, Chief Medical Officer 28 février 2026 M 323 430 0 0 $0
Lisa Defrancesco SVP, IR and Corp Comm 28 février 2026 M 93 869 0 0 $0
Brian T Crum SVP, General Counsel & Secr. 28 février 2026 M 428 802 0 0 $0
Kristen Alexander VP, Finance and Accounting 28 février 2025 M 76 368 0 0 $0
Alan J Main EVP, Innov & Chem Sciences 28 février 2025 M 339 104 0 0 $0
Brian Corrigan SVP, Regulatory & QA 13 février 2025 A · 0 0 $0
Kenneth B. Kassler-Taub SVP, Regulatory & QA 28 février 2024 M 162 672 0 0 $0
Thomas Garner SVP, Chief Commercial Officer 8 février 2024 A · 0 0 $0
Kiernan Seth VP, Chief Commercial Officer 28 février 2023 M 53 136 0 0 $0
James F Tessmer VP, Finance & Accounting 15 mars 2021 M 71 766 0 0 $0
Alexander A Santini EVP and CCO 22 avril 2020 F 55 584 0 0 $0
Pablo Lapuerta EVP and CMO 22 avril 2020 F 85 719 0 0 $0
John Northcott VP, Marketing, Comm Strategy 2 mars 2015 M 8 235 0 0 $0
Brian P Zambrowicz EVP, Chief Scientific Officer 28 février 2014 M 278 703 0 0 $0
Steven Alan Tragash VP, Corporate Affairs 15 février 2010 A · 0 0 $0
Philip M Brown SVP, Clinical Development 15 février 2010 A 27 306 0 0 $0
James R Piggott PHD SVP of Pharm Bio 7 février 2008 A 0 0 0 $0
Lance K Ishimoto SVP, Intellectual Property 7 février 2008 A 10 200 0 0 $0
Tamar D Howson EVP of Bus Dev 7 février 2008 A · 0 0 $0
Walter F Colbert SVP, HR and Corp Serv 13 février 2007 A · 0 0 $0
Randall B Riggs SVP, Corp Licensing 23 février 2004 M 15 000 0 0 $0
Christophe Person VP Informatics 12 janvier 2004 M 0 0 0 $0
Ivan Cheung Administrateur 3 juin 2026 M 89 312 0 0 $0
Diane E. Sullivan Administrateur 3 juin 2026 M 126 122 0 0 $0
Judith L Swain Administrateur 3 juin 2026 M 174 486 0 0 $0
Amouyal Philippe Administrateur 3 juin 2026 M 374 486 0 0 $0
Sam L Barker Administrateur 3 juin 2026 M 213 771 0 0 $0
Christopher J Sobecki Administrateur 3 juin 2026 M 293 177 0 0 $0
Raymond Debbane Administrateur 3 juin 2026 M 1 995 498 7 0 $723 048
Robert J Lefkowitz MD Administrateur 13 mai 2024 A 48 364 0 0 $0
Frank Palantoni Administrateur 21 mai 2023 M 40 332 0 0 $0
Alan S Nies Administrateur 21 mai 2023 M 41 046 0 0 $0
Invus C.V. Administrateur 31 décembre 2020 J 0 0 0 $0
Kathleen M Wiltsey Administrateur 24 avril 2009 A · 0 0 $0
Clayton Stuart Rose Administrateur 26 juin 2007 P 25 000 0 0 $0
Barry Mills Administrateur 26 avril 2007 A 25 000 0 0 $0
Patricia M Cloherty Administrateur 27 avril 2006 A · 0 0 $0
Thomas C Caskey Administrateur 13 octobre 2005 P 6 300 0 0 $0
Praveen Tyle · 28 février 2021 M 120 791 0 0 $0

Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché

Détention d'ETF Détenu par 16 ETFs

20

Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.

Fonds Poids Unités Au Source
BBC · ETFis Series Trust I 0,81% 161 882 NS 31 juillet 2026 N-PORT
PILL · Direxion Shares ETF Trust 0,45% 40 310 NS 31 juillet 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0,42% 53 319 SH 2 octobre 2026 Quotidien
IWC · iShares Trust 0,12% 842 323 SH 11 septembre 2026 Quotidien
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 266 401 SH 19 août 2026 Quotidien
IWO · iShares Trust 0,03% 2 343 443 SH 11 septembre 2026 Quotidien
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 1 432 882 SH 19 août 2026 Quotidien
RSSL · Global X Funds 0,02% 118 391 NS 31 juillet 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 255 130 SH 2 octobre 2026 Quotidien
IWM · iShares Trust 0,02% 6 319 224 SH 11 septembre 2026 Quotidien
VXF · VANGUARD INDEX FUNDS 0,01% 2 594 934 SH 19 août 2026 Quotidien
VHT · VANGUARD WORLD FUND 0,01% 637 561 SH 19 août 2026 Quotidien
WSML · iShares Trust 0,01% 17 992 SH 11 septembre 2026 Quotidien
IWV · iShares Trust 0,00% 85 389 SH 3 septembre 2026 Quotidien
VTI · VANGUARD INDEX FUNDS 0,00% 7 083 651 SH 19 août 2026 Quotidien
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 20 905 SH 19 août 2026 Quotidien

LXRX Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse

21
notation · 11 analystes ACHAT
Objectif médian $4.55 +150,0%
3 27,3% Achat fort
5 45,5% Achat
3 27,3% Conserver
0 0,0% Vente
0 0,0% Vente forte

Objectif de cours à 12 mois

6 analystes · 2026-09-30

Objectif moyen $4.55 +149,8%

← En dessous de tous les objectifs Prix actuel $1.82
Bas$2.00 Moyenne$4.55 Haut$8.00

Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur

22

Base F.A., prix à la clôture de la dernière fin d'exercice de chaque société.

Ticker Capitalisation Boursière P/E Revenus Année/Année Marge Nette ROE Marge Brute
LXRX $421M -8.2 60.2% -101.1% -39.7% ·
ANRO $568M -8.1 · · -46.1% ·
ALMS · -3.4 · -1011.8% -61.9% ·
APMD · · · · · ·
SGP · · · · 50.0% ·
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
ACRS $363M -5.7 -58.2% -829.6% -55.3% ·
ZVRA $509M 6.6 350.9% 78.2% 61.2% ·
AQST $788M -8.3 -22.6% -188.1% 157.7% ·
PHAT $1.18B -5.5 216.9% -126.4% 52.4% 87.1%

Dernières actualités Actualités récentes mentionnant cette entreprise

23

Mes métriques Votre watchlist personnelle — lignes sélectionnées de Fondamentaux Complets

26

Choisissez les indicateurs qui vous importent — cliquez sur le + à côté de n'importe quelle ligne dans les Fondamentaux complets ci-dessus.

Votre sélection est enregistrée et vous suit sur tous les tickers.

Source : Dépôt SEC 10-Q le Aoû 6, 2026