LYEL Lyell Immunopharma, Inc. - Common Stock
LYEL Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
LYEL Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
LYEL Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 3 23,1%
- Achat 8 61,5%
- Conserver 1 7,7%
- Vente 1 7,7%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
7 analystes · 2026-08-14Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-1.92 | $-2.06 | 0.14% |
| 31 mars 2026 | $-1.10 | $-2.41 | 1.3% |
| 31 décembre 2025 | $-7.50 | $-2.28 | -5.2% |
| 30 septembre 2025 | $-2.13 | $-2.70 | 0.57% |
| 30 juin 2025 | $-2.89 | $-3.65 | 0.77% |
| 31 mars 2025 | $-3.54 | $-3.67 | 0.13% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| LYEL | $654M | -1.9 | -41.0% | -762355.6% | -100.3% | — |
| SABS | — | — | — | — | — | — |
| ABEO | $290M | 5.2 | 147.5% | 1223.1% | 44.1% | — |
| IMRX | — | -5.2 | — | — | -45.3% | — |
| TLSI | — | — | — | — | — | — |
| IKT | $270M | -4.2 | 111.0% | -1299.0% | -38.2% | — |
| AGEN | $111M | — | 10.4% | -2.7% | 1.0% | — |
| FATE | $113M | -0.9 | -51.2% | -2051.1% | -58.2% | — |
| VNDA | $521M | -2.4 | 8.7% | -102.0% | -54.2% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue | $36.0K | $61.0K | $130.0K | $85M | $11M | $8M | |
| R&D Expense | · | · | $183M | $159M | $139M | $182M | |
| SG&A Expense | $45M | $52M | $67M | $117M | $89M | $47M | |
| Operating Expenses | $269M | $359M | $247M | $272M | $225M | $220M | |
| Operating Income | $-269M | $-359M | $-247M | $-187M | $-215M | $-212M | |
| Other Non-op | $-18M | $5M | $2M | $2M | $-161.0K | $2M | |
| Income Tax | $0 | · | · | · | · | · | |
| Net Income | $-274M | $-343M | $-235M | $-183M | $-250M | $-204M | |
| EPS (Basic) | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 | $-15.69 | |
| EPS (Diluted) | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 | $-15.69 | |
| Shares (Basic) | 17,093,000 | 13,074,000 | 12,549,000 | 247,080,000 | 135,918,000 | 13,258,000 | |
| Shares (Diluted) | 17,093,000 | 13,074,000 | 12,549,000 | 247,080,000 | 135,918,000 | 13,258,000 | |
| EBITDA | $-258M | $-339M | $-227M | $-169M | $-201M | · |
Bilan 21
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $60M | $106M | $146M | $124M | $294M | $140M | |
| Short-term Investments | $187M | $265M | $401M | $517M | $321M | $472M | |
| Prepaid Expense | $14M | $9M | $8M | $11M | $11M | $5M | |
| Current Assets | $261M | $380M | $555M | $651M | $626M | $618M | |
| PP&E (Net) | $35M | $48M | $103M | $123M | $120M | $77M | |
| PP&E (Gross) | $109M | $119M | $154M | $155M | $135M | $82M | |
| Accum. Depreciation | $74M | $71M | $52M | $32M | $15M | $5M | |
| Other Non-current Assets | $5M | $5M | $4M | $5M | $3M | $3M | |
| Total Assets | $340M | $491M | $750M | $938M | $1.13B | $908M | |
| Accounts Payable | $3M | $5M | $5M | $4M | $3M | $9M | |
| Current Liabilities | $49M | $54M | $35M | $37M | $47M | $49M | |
| Capital Leases | $42M | $51M | $57M | $63M | $67M | $51M | |
| Other Non-current Liabilities | $517.0K | $3M | $4M | $4M | $5M | $532.0K | |
| Total Liabilities | $92M | $108M | $95M | $104M | $198M | $190M | |
| Common Stock | $2.0K | $1.0K | $25.0K | $25.0K | $24.0K | $2.0K | |
| Paid-in Capital | $1.87B | $1.73B | $1.66B | $1.61B | $1.52B | $41M | |
| Retained Earnings | $-1.62B | $-1.35B | $-1.00B | $-767M | $-584M | $-334M | |
| AOCI | $242.0K | $291.0K | $-94.0K | $-8M | $-2M | $256.0K | |
| Stockholders' Equity | $248M | $383M | $655M | $833M | $930M | $-293M | |
| Liabilities + Equity | $340M | $491M | $750M | $938M | $1.13B | $908M | |
| Shares Outstanding | 21,251,000 | 14,744,000 | 12,698,000 | 12,479,000 | 242,738,000 | 15,570,000 |
Flux de trésorerie 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $12M | $20M | $20M | $18M | $14M | $4M | |
| Stock-based Comp | $42M | $33M | $47M | $82M | $62M | $33M | |
| Restructuring | · | · | $6M | · | · | · | |
| Other Non-cash | $71M | $128M | $4M | $-86M | $48M | · | |
| Operating Cash Flow | $-150M | $-162M | $-164M | $-170M | $-126M | $-161M | |
| CapEx | $780.0K | $464.0K | $3M | $24M | $66M | $51M | |
| Investing Cash Flow | $54M | $122M | $184M | $-12M | $-122M | $-274M | |
| Stock Issued | $50M | $0 | $0 | · | · | · | |
| Stock Repurchased | · | · | · | $0 | $0 | $12M | |
| Net Stock Activity | $50M | · | · | $0 | $0 | · | |
| Financing Cash Flow | $50M | $1M | $2M | $11M | $401M | $477M | |
| Net Change in Cash | $-46M | $-39M | $22M | $-170M | $153M | $42M | |
| Free Cash Flow | $-151M | $-163M | $-166M | $-194M | $-192M | · |
Rentabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Margin | -748344.4% | -588123.0% | -190006.1% | -220.9% | -2016.7% | · | |
| Net Margin | -762355.6% | -562285.2% | -180486.1% | -216.2% | -2349.5% | · | |
| EBITDA Margin | -716291.7% | -555941.0% | -174429.2% | -199.6% | -1888.8% | · | |
| ROA | -66.1% | -55.3% | -27.8% | -17.7% | -24.6% | · | |
| ROE | -100.3% | -75.1% | -34.7% | -22.1% | -26.1% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 5.3 | 7.1 | 16.1 | 17.6 | 13.4 | · | |
| Quick Ratio | 5.0 | 6.9 | 15.8 | 17.3 | 13.2 | · |
Efficacité 1
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | · |
Taux de croissance 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue YoY | -41.0% | -53.1% | -99.9% | 695.1% | 37.3% | · | |
| Revenue CAGR 3Y | -92.5% | -82.1% | -74.4% | · | · | · | |
| Revenue CAGR 5Y | -65.8% | · | · | · | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $36.0K | $61.0K | $130.0K | $85M | $11M | · | |
| Net Income TTM | $-274M | $-343M | $-235M | $-183M | $-250M | · | |
| Market Cap | $654M | $3.77B | $9.85B | $17.32B | $37.58B | · | |
| P/E | -1.9 | -0.5 | -2.1 | -93.8 | -84.1 | · | |
| P/S | 18169.6 | 61875.6 | 75796.7 | 204.5 | 3528.2 | · | |
| P/B | 2.6 | 9.9 | 15.0 | 20.8 | 40.4 | · | |
| P / Tangible Book | 2.6 | 9.9 | 15.0 | 20.8 | 40.4 | · | |
| P / Cash Flow | -4.4 | -23.2 | -60.2 | -102.1 | -297.6 | · | |
| P / FCF | -4.3 | -23.2 | -59.2 | -89.4 | -196.0 | · | |
| Earnings Yield | -52.2% | -204.9% | -48.2% | -1.1% | -1.2% | · |
Compte de résultat 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $4.0K | $2.0K | $6.0K | $15.0K | $8.0K | $7.0K | $11.0K | $34.0K | $13.0K | $3.0K | $13.0K | $25.0K | $27.0K | $65.0K | $48M | $3.0K | |
| R&D Expense | $40M | $37M | · | $28M | $35M | $43M | · | $40M | $40M | $43M | · | $44M | $47M | $45M | · | $42M | |
| SG&A Expense | $10M | $10M | $11M | $11M | $10M | $14M | $15M | $12M | $12M | $13M | $13M | $16M | $19M | $19M | $26M | $26M | |
| Operating Expenses | $47M | $44M | $128M | $37M | $47M | $57M | $201M | $51M | $52M | $56M | $60M | $59M | $66M | $63M | $63M | $66M | |
| Operating Income | $-47M | $-44M | $-128M | $-37M | $-47M | $-57M | $-201M | $-51M | $-52M | $-56M | $-60M | $-59M | $-66M | $-63M | $-15M | $-66M | |
| Other Non-op | $398.0K | $18M | $-16M | $-5M | $1M | $1M | $4M | $-43.0K | $-645.0K | $1M | $-506.0K | $2M | $-326.0K | $1M | $3M | $-1M | |
| Net Income | $-45M | $-24M | $-141M | $-39M | $-43M | $-52M | $-192M | $-45M | $-46M | $-61M | $-53M | $-51M | $-64M | $-67M | $-8M | $-70M | |
| EPS (Basic) | $-1.92 | $-1.10 | $-10.86 | $-2.13 | $-2.89 | $-3.54 | $-18.92 | $-3.48 | $-3.59 | $-0.24 | $-17.97 | $-0.20 | $-0.26 | $-0.27 | $-0.03 | $-0.28 | |
| EPS (Diluted) | $-1.92 | $-1.10 | $-10.86 | $-2.13 | $-2.89 | $-3.54 | $-18.92 | $-3.48 | $-3.59 | $-0.24 | $-17.97 | $-0.20 | $-0.26 | $-0.27 | $-0.03 | $-0.28 | |
| Shares (Basic) | 23,364,000 | 21,876,000 | -311,066,000 | 18,268,000 | 14,793,000 | 14,755,000 | -266,763,000 | 12,815,000 | 12,770,000 | 254,252,000 | -738,564,000 | 251,318,000 | 250,204,000 | 249,591,000 | -491,730,000 | 248,320,000 | |
| Shares (Diluted) | 23,364,000 | 21,876,000 | -311,066,000 | 18,268,000 | 14,793,000 | 14,755,000 | -266,763,000 | 12,815,000 | 12,770,000 | 254,252,000 | -738,564,000 | 251,318,000 | 250,204,000 | 249,591,000 | -491,730,000 | 248,320,000 | |
| EBITDA | $-47M | $-42M | · | $-37M | $-47M | $-54M | · | $-51M | $-52M | $-51M | · | $-59M | $-66M | $-58M | · | $-66M |
Bilan 21
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $73M | $91M | $60M | $124M | $99M | $120M | $106M | $100M | $133M | $126M | $146M | $286M | $224M | $109M | $124M | $116M | |
| Short-term Investments | $131M | $163M | $187M | $196M | $178M | $181M | $265M | $340M | $358M | $401M | · | $289M | $371M | $503M | · | $532M | |
| Prepaid Expense | $9M | $13M | $14M | $9M | $5M | $8M | $9M | $9M | $9M | $8M | · | $11M | $11M | $12M | · | $12M | |
| Current Assets | $214M | $267M | $261M | $328M | $282M | $309M | $380M | $450M | $500M | $534M | · | $587M | $606M | $624M | · | $660M | |
| PP&E (Net) | $31M | $33M | $35M | $37M | $39M | $44M | $48M | $88M | $93M | $98M | · | $108M | $114M | $119M | · | $126M | |
| PP&E (Gross) | · | · | $109M | · | · | · | $119M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $74M | · | · | · | $71M | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $6M | $5M | $5M | $3M | $3M | $3M | $5M | $5M | $4M | $4M | · | $4M | $5M | $5M | · | $3M | |
| Total Assets | $311M | $351M | $340M | $408M | $385M | $430M | $491M | $619M | $654M | $694M | · | $795M | $835M | $880M | · | $977M | |
| Accounts Payable | $4M | $5M | $3M | $3M | $3M | $4M | $5M | $4M | $4M | $5M | · | $4M | $6M | $6M | · | $5M | |
| Current Liabilities | $40M | $37M | $49M | $32M | $37M | $41M | $54M | $34M | $31M | $32M | · | $35M | $34M | $31M | · | $51M | |
| Capital Leases | $37M | $39M | $42M | $44M | $47M | $49M | $51M | $51M | $53M | $55M | · | $59M | $60M | $62M | · | $65M | |
| Other Non-current Liabilities | $537.0K | $527.0K | $517.0K | $3M | $3M | $3M | $3M | $4M | $3M | $4M | · | $4M | $4M | $4M | · | $4M | |
| Total Liabilities | $77M | $77M | $92M | $79M | $87M | $93M | $108M | $89M | $88M | $91M | · | $97M | $98M | $97M | · | $157M | |
| Common Stock | $2.0K | $2.0K | $2.0K | $2.0K | $1.0K | $30.0K | $1.0K | $26.0K | $26.0K | $25.0K | · | $25.0K | $25.0K | $25.0K | · | $25.0K | |
| Paid-in Capital | $1.92B | $1.92B | $1.87B | $1.81B | $1.74B | $1.73B | $1.73B | $1.68B | $1.68B | $1.67B | · | $1.65B | $1.64B | $1.62B | · | $1.59B | |
| Retained Earnings | $-1.69B | $-1.64B | $-1.62B | $-1.48B | $-1.44B | $-1.40B | $-1.35B | $-1.15B | $-1.11B | $-1.06B | · | $-949M | $-898M | $-834M | · | $-759M | |
| AOCI | $-158.0K | $-9.0K | $242.0K | $201.0K | $57.0K | $158.0K | $291.0K | $760.0K | $-397.0K | $-404.0K | · | $-1M | $-2M | $-4M | · | $-10M | |
| Stockholders' Equity | $234M | $274M | $248M | $329M | $299M | $337M | $383M | $531M | $567M | $603M | $655M | $698M | $737M | $784M | $833M | $820M | |
| Liabilities + Equity | $311M | $351M | $340M | $408M | $385M | $430M | $491M | $619M | $654M | $694M | · | $795M | $835M | $880M | · | $977M | |
| Shares Outstanding | 23,397,000 | 23,328,000 | 21,251,000 | 19,294,000 | 14,831,000 | 295,284,000 | 14,744,000 | 256,564,000 | 255,948,000 | 254,927,000 | 12,698,000 | 251,869,000 | 251,027,000 | 249,609,000 | 249,567,000 | 249,240,000 |
Flux de trésorerie 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $3M | $3M | $3M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | $5M | |
| Stock-based Comp | $5M | $4M | $26M | $5M | $5M | $6M | $8M | $8M | $8M | $9M | $8M | $11M | $14M | $14M | $18M | $19M | |
| Other Non-cash | · | $-21M | · | · | · | $-12M | · | · | · | $4M | · | · | · | $2M | · | · | |
| Operating Cash Flow | $-34M | $-39M | $-32M | $-29M | $-34M | $-55M | $-47M | $-35M | $-38M | $-42M | $-41M | $-38M | $-39M | $-46M | $-40M | $-37M | |
| CapEx | $256.0K | $89.0K | $304.0K | $62.0K | $168.0K | $246.0K | $44.0K | $59.0K | $331.0K | $30.0K | $25.0K | $195.0K | $933.0K | $2M | $5M | $3M | |
| Investing Cash Flow | $16M | $17M | $-31M | $3M | $13M | $69M | $54M | $2M | $45M | $22M | $-101M | $100M | $153M | $32M | $47M | $-57M | |
| Stock Issued | · | · | $0 | · | · | · | $0 | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $522.0K | $52M | $222.0K | $50M | $183.0K | $1.0K | $437.0K | $0 | $862.0K | $27.0K | $759.0K | $-143.0K | $1M | $-69.0K | $863.0K | $5M | |
| Net Change in Cash | $-18M | $31M | $-63M | $25M | $-22M | $15M | $7M | $-33M | $8M | $-20M | $-141M | $62M | $115M | $-14M | $7M | $-89M | |
| Free Cash Flow | · | $-39M | · | · | · | $-55M | · | · | · | $-42M | · | · | · | $-48M | · | · |
Rentabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1183425.0% | -2213050.0% | · | -248353.3% | -589250.0% | -819528.6% | · | -148544.1% | -396369.2% | -1852500.0% | · | -236156.0% | -244092.6% | -96240.0% | · | -2214566.7% | |
| Net Margin | -1118875.0% | -1207650.0% | · | -258973.3% | -533550.0% | -745642.9% | · | -131126.5% | -352376.9% | -2022233.3% | · | -203412.0% | -236629.6% | -103013.9% | · | -2341800.0% | |
| EBITDA Margin | -1183425.0% | -2096450.0% | · | -248353.3% | -589250.0% | -770371.4% | · | -148544.1% | -396369.2% | -1685033.3% | · | -236156.0% | -244092.6% | -88506.2% | · | -2214566.7% | |
| ROA | -12.8% | -6.2% | · | -7.6% | -8.2% | -9.3% | · | -6.3% | -6.2% | -7.7% | · | -5.7% | -6.9% | -6.9% | · | -6.5% | |
| ROE | -16.8% | -7.9% | · | -9.0% | -9.9% | -11.1% | · | -7.3% | -7.0% | -8.8% | · | -6.7% | -8.0% | -8.0% | · | -7.8% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.4 | 7.2 | · | 10.3 | 7.6 | 7.5 | · | 13.4 | 16.2 | 16.5 | · | 16.7 | 17.6 | 20.3 | · | 12.9 | |
| Quick Ratio | 5.1 | 6.9 | · | 10.0 | 7.5 | 7.3 | · | 13.1 | 15.9 | 16.3 | · | 16.4 | 17.3 | 19.9 | · | 12.7 |
Efficacité 1
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $29.0K | $32.0K | · | $64.0K | $62.0K | $57.0K | · | $75.0K | $68.0K | $120.0K | · | $120.0K | $36M | $36M | · | $39M | |
| Net Income TTM | $-150M | $-158M | · | $-178M | $-185M | $-203M | · | $-202M | $-221M | $-242M | · | $-252M | $-237M | $-242M | · | $-224M | |
| Market Cap | $329M | $468M | · | $313M | $131M | $3.18B | · | $7.08B | $7.42B | $11.37B | · | $7.40B | $15.97B | $11.78B | · | $36.54B | |
| P/E | -1.7 | -2.1 | · | -1.9 | -0.9 | -1.4 | · | -3.7 | -6.8 | -46.0 | · | -29.1 | -66.2 | -48.2 | · | -161.1 | |
| P/S | 11335.4 | 14623.7 | · | 4895.9 | 2114.6 | 55741.3 | · | 94415.6 | 109154.3 | 94747.9 | · | 61707.9 | 445.5 | 324.0 | · | 935.6 | |
| P/B | 1.4 | 1.7 | · | 1.0 | 0.4 | 9.4 | · | 13.3 | 13.1 | 18.9 | · | 10.6 | 21.7 | 15.0 | · | 44.6 | |
| P / Tangible Book | 1.4 | 1.7 | · | 1.0 | 0.4 | 9.4 | · | 13.3 | 13.1 | 18.9 | · | 10.6 | 21.7 | 15.0 | · | 44.6 | |
| P / Cash Flow | · | -12.2 | · | · | · | -58.0 | · | · | · | -270.6 | · | · | · | -254.9 | · | · | |
| P / FCF | · | -12.1 | · | · | · | -57.8 | · | · | · | -270.4 | · | · | · | -246.8 | · | · | |
| Earnings Yield | -57.2% | -48.2% | · | -53.4% | -114.7% | -69.6% | · | -27.2% | -14.8% | -2.2% | · | -3.4% | -1.5% | -2.1% | · | -0.62% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $36.0K | $61.0K | $130.0K | $85M | $11M |
| Marge d'exploitation % | -748344.4% | -588123.0% | -190006.1% | -220.9% | -2016.7% |
| Résultat net | $-274M | $-343M | $-235M | $-183M | $-250M |
| BPA dilué | $-16.06 | $-26.23 | $-18.70 | $-0.74 | $-1.84 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 5.3 | 7.1 | 16.1 | 17.6 | 13.4 |
| Ratio de liquidité réduite | 5.0 | 6.9 | 15.8 | 17.3 | 13.2 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-151M | $-163M | $-166M | $-194M | $-192M |
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Détenteurs institutionnels (13F) 94 déclarants · $203.2M total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 30 (+14 vs T. préc.) | 9 (+3 vs T. préc.) | 25 (+1 vs T. préc.) | 19 (+11 vs T. préc.) | +295K |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| ARCH Venture Management, LLC | $45 525 211 | 3 247 162 | 22,41% | Actions |
| MWG Caph Ltd | $31 029 810 | 1 008 116 | 15,27% | Actions |
| GSK plc | $21 252 859 | 1 512 659 | 10,46% | Actions |
| MWG Management Ltd. | $16 371 804 | 1 008 116 | 8,06% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $11 054 175 | 786 774 | 5,44% | Actions |
| Orland Properties Ltd | $10 603 507 | 754 698 | 5,22% | Actions |
| Almitas Capital LLC | $8 168 768 | 581 407 | 4,02% | Actions |
| Foresite Capital Management V, LLC | $6 693 223 | 476 386 | 3,29% | Actions |
| MILLENNIUM MANAGEMENT LLC | $5 162 996 | 367 473 | 2,54% | Actions |
| Opaleye Management Inc. | $4 833 551 | 344 025 | 2,38% | Actions |
| venBio Partners LLC | $4 744 643 | 337 697 | 2,34% | Actions |
| Alphabet Inc. | $4 120 247 | 293 256 | 2,03% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $3 712 787 | 264 152 | 1,83% | Actions |
| VANGUARD GROUP INC | $2 675 552 | 86 925 | 1,32% | Actions |
| STATE STREET CORP | $2 603 774 | 185 322 | 1,28% | Actions |
| HSG Holding Ltd | $2 139 801 | 152 299 | 1,05% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 829 169 | 130 190 | 0,90% | Actions |
| Qube Research & Technologies Ltd | $1 552 961 | 110 531 | 0,76% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 511 359 | 107 570 | 0,74% | Actions |
| Velan Capital Investment Management LP | $1 475 250 | 105 000 | 0,73% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $1 307 985 | 93 095 | 0,64% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 291 069 | 91 891 | 0,64% | Actions |
| MIC Capital Management UK LLP | $1 222 743 | 87 028 | 0,60% | Actions |
| GOLDMAN SACHS GROUP INC | $1 219 245 | 86 779 | 0,60% | Actions |
| MARSHALL WACE, LLP | $1 188 350 | 84 580 | 0,58% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $779 269 | 55 464 | 0,38% | Actions |
| TWO SIGMA INVESTMENTS, LP | $743 624 | 52 927 | 0,37% | Actions |
| Squarepoint Ops LLC | $594 624 | 42 322 | 0,29% | Actions |
| Ikarian Capital, LLC | $577 188 | 41 081 | 0,28% | Actions |
| JANE STREET GROUP, LLC | $476 309 | 33 901 | 0,23% | Actions |
| CANADA PENSION PLAN INVESTMENT BOARD | $413 225 | 29 411 | 0,20% | Actions |
| Point72 Asset Management, L.P. | $366 424 | 26 080 | 0,18% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $363 895 | 25 900 | 0,18% | Option d'achat |
| AMERICAN CENTURY COMPANIES INC | $344 787 | 24 540 | 0,17% | Actions |
| Jump Financial, LLC | $308 482 | 21 956 | 0,15% | Actions |
| Clearstead Advisors, LLC | $280 410 | 19 958 | 0,14% | Actions |
| EntryPoint Capital, LLC | $272 710 | 19 410 | 0,13% | Actions |
| CITADEL ADVISORS LLC | $262 665 | 18 695 | 0,13% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $252 900 | 18 000 | 0,12% | Actions |
| CITADEL ADVISORS LLC | $251 495 | 17 900 | 0,12% | Option de vente |
| Susquehanna Portfolio Strategies, LLC | $251 144 | 17 875 | 0,12% | Actions |
| MORGAN STANLEY | $239 257 | 17 029 | 0,12% | Actions |
| CITADEL ADVISORS LLC | $238 850 | 17 000 | 0,12% | Option d'achat |
| Allspring Global Investments Holdings, LLC | $226 837 | 16 145 | 0,11% | Actions |
| RHUMBLINE ADVISERS | $217 234 | 15 462 | 0,11% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $199 510 | 14 200 | 0,10% | Option de vente |
| Nuveen, LLC | $176 960 | 12 595 | 0,09% | Actions |
| Graham Capital Management, L.P. | $163 008 | 11 602 | 0,08% | Actions |
| Brevan Howard Capital Management LP | $162 376 | 11 557 | 0,08% | Actions |
| BANK OF AMERICA CORP /DE/ | $152 737 | 10 871 | 0,08% | Actions |
| Walleye Capital LLC | $146 837 | 10 451 | 0,07% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $133 545 | 9 505 | 0,07% | Actions |
| DEUTSCHE BANK AG\ | $129 091 | 9 188 | 0,06% | Actions |
| Bank of New York Mellon Corp | $127 799 | 9 096 | 0,06% | Actions |
| BlackRock, Inc. | $111 051 | 7 904 | 0,05% | Actions |
| WELLS FARGO & COMPANY/MN | $110 714 | 7 880 | 0,05% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $110 222 | 7 845 | 0,05% | Actions |
| Vanguard Global Advisers, LLC | $72 568 | 5 165 | 0,04% | Actions |
| CITIGROUP INC | $62 972 | 4 482 | 0,03% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $60 879 | 4 333 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $57 605 | 4 100 | 0,03% | Actions |
| Invesco Ltd. | $52 716 | 3 752 | 0,03% | Actions |
| China Universal Asset Management Co., Ltd. | $52 182 | 3 714 | 0,03% | Actions |
| JPMORGAN CHASE & CO | $49 738 | 3 901 | 0,02% | Actions |
| BARCLAYS PLC | $49 147 | 3 498 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $48 416 | 3 446 | 0,02% | Actions |
| FMR LLC | $30 222 | 2 151 | 0,01% | Actions |
| NORTHERN TRUST CORP | $20 583 | 1 465 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $19 164 | 1 364 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $14 668 | 1 044 | 0,01% | Actions |
| Legal & General Group Plc | $12 884 | 917 | 0,01% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $12 715 | 905 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $11 999 | 854 | 0,01% | Actions |
| JONES FINANCIAL COMPANIES LLLP | $11 900 | 1 025 | 0,01% | Actions |
| Russell Investments Group, Ltd. | $10 565 | 752 | 0,01% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $6 351 | 452 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $6 000 | 418 | 0,00% | Actions |
| Truvestments Capital LLC | $4 215 | 300 | 0,00% | Actions |
| UBS Group AG | $3 513 | 250 | 0,00% | Actions |
| SIMPLEX TRADING, LLC | $3 175 | 226 | 0,00% | Actions |
| Sterling Capital Management LLC | $2 670 | 190 | 0,00% | Actions |
| Quarry LP | $2 515 | 179 | 0,00% | Actions |
| GROUP ONE TRADING LLC | $1 236 | 88 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $955 | 68 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $836 | 59 748 | 0,00% | Actions |
| US BANCORP \DE\ | $815 | 58 | 0,00% | Actions |
| Cornerstone Financial Management LLC | $646 | 46 | 0,00% | Actions |
| HRT FINANCIAL LP | $513 | 36 575 | 0,00% | Actions |
| GAMMA Investing LLC | $492 | 35 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $431 | 30 657 | 0,00% | Actions |
| GSA CAPITAL PARTNERS LLP | $368 | 26 225 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $351 | 25 | 0,00% | Actions |
| Optiver Holding B.V. | $281 | 20 | 0,00% | Actions |
| CWM, LLC | $40 | 2 | 0,00% | Actions |
Initiés de la société 21 initiés · 7 dirigeants · 10 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Elizabeth Homans | Chief Executive Officer | 16 mars 2022 A | — | 0 | 0 | $0 |
| Charles W. Newton | Chief Financial Officer | 9 février 2024 A | 48 729 | 0 | 0 | $0 |
| David Shook | Chief Medical Officer | 10 juin 2026 S | 20 923 | 0 | 1 | $-24 989 |
| Matthew Lang | Chief Business Officer | 9 février 2024 A | 50 000 | 0 | 0 | $0 |
| Tina M. Albertson | Chief Medical Officer | 24 février 2023 A | — | 0 | 0 | $0 |
| Rahsaan Thompson | Chief Legal Officer | 24 février 2023 A | — | 0 | 0 | $0 |
| Heather D Turner | Chief General Counsel | 16 mars 2022 A | — | 0 | 0 | $0 |
| Mark Bachleda | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Elizabeth G Nabel | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Richard Klausner | Administrateur | 10 juin 2026 A | 930 880 | 0 | 0 | $0 |
| Sumant Ramachandra | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Cathy Friedman | Administrateur | 10 juin 2026 A | 236 370 | 0 | 0 | $0 |
| Otis W Brawley | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| William Jl Rieflin | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Hans Edgar Bishop | Administrateur | 8 septembre 2023 A | 4 685 614 | 0 | 0 | $0 |
| Robert Nelsen | Administrateur | 8 septembre 2023 A | 18 206 358 | 0 | 0 | $0 |
| Innovative Cellular Therapeutics Holdings Ltd | Détenteur de 10% | 27 juillet 2026 J | 2 818 980 | 0 | 2 | $-274 |
| Veronica Sanchez Bulis | — | 10 août 2026 S | 14 799 | 0 | 2 | $-13 008 |
| Gary K. Lee | — | 10 août 2026 S | 17 677 | 0 | 2 | $-4 339 |
| Stephen J. Hill | — | 10 août 2026 S | 17 805 | 0 | 2 | $-2 960 |
| Lynn Seely | — | 10 août 2026 S | 73 488 | 0 | 5 | $-204 066 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Détention d'ETF Détenu par 21 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| IWC · iShares Trust | 0,03% | 31 581 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,02% | 1 253 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,02% | 787 NS | 31 mai 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 23 005 NS | 31 mai 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 8 183 SH | 8 août 2026 | Quotidien |
| IWN · iShares Trust | 0,01% | 88 790 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,01% | 55 895 SH | 8 août 2026 | Quotidien |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 67 448 NS | 31 mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,00% | 9 023 SH | 8 août 2026 | Quotidien |
| IWM · iShares Trust | 0,00% | 222 372 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,00% | 12 766 NS | 30 avril 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 339 NS | 30 avril 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 9 101 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 1 396 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 163 755 SH | 8 août 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 604 461 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,00% | 54 398 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 1 151 SH | 8 août 2026 | Quotidien |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 346 NS | 31 mai 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 409 NS | 30 avril 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0,00% | 28 159 SH | 8 août 2026 | Quotidien |