PHVS — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $227 027 106 | 6 565 272 | 10,21% | Actions |
| GENERAL ATLANTIC, L.P. | $226 525 177 | 6 550 757 | 10,18% | Actions |
| Foresite Capital Management IV, LLC | $165 243 331 | 4 778 581 | 7,43% | Actions |
| venBio Partners LLC | $160 569 809 | 4 643 430 | 7,22% | Actions |
| VIKING GLOBAL INVESTORS LP | $126 331 460 | 3 653 310 | 5,68% | Actions |
| EQT Fund Management S.a r.l. | $118 422 979 | 3 424 609 | 5,32% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $116 743 532 | 3 376 042 | 5,25% | Actions |
| Bain Capital Life Sciences Investors, LLC | $92 519 101 | 2 675 509 | 4,16% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $82 747 658 | 2 392 934 | 3,72% | Actions |
| Polar Capital Holdings Plc | $80 446 532 | 2 326 389 | 3,62% | Actions |
| Point72 Asset Management, L.P. | $56 752 696 | 1 641 200 | 2,55% | Actions |
| Commodore Capital LP | $49 276 500 | 1 425 000 | 2,22% | Actions |
| NOVO HOLDINGS A/S | $48 412 000 | 1 400 000 | 2,18% | Actions |
| Saturn V Capital Management LP | $45 442 339 | 1 314 122 | 2,04% | Actions |
| TCG Crossover Management, LLC | $34 864 559 | 1 008 229 | 1,57% | Actions |
| Sofinnova Investments, Inc. | $30 475 319 | 881 299 | 1,37% | Actions |
| 5AM Venture Management, LLC | $27 581 008 | 797 600 | 1,24% | Actions |
| Seven Fleet Capital Management LP | $26 782 245 | 774 501 | 1,20% | Actions |
| BlackRock, Inc. | $26 676 879 | 771 454 | 1,20% | Actions |
| Cormorant Asset Management, LP | $25 935 000 | 750 000 | 1,17% | Actions |
| Soleus Capital Management, L.P. | $25 274 764 | 730 907 | 1,14% | Actions |
| Jones Hill Capital LP | $23 441 056 | 677 879 | 1,05% | Actions |
| Patient Square Capital LP | $23 210 407 | 671 209 | 1,04% | Actions |
| Foresite Capital Management V, LLC | $22 966 030 | 664 142 | 1,03% | Actions |
| Kynam Capital Management, LP | $22 884 871 | 661 795 | 1,03% | Actions |
| Rock Springs Capital Management LP | $22 419 355 | 648 333 | 1,01% | Actions |
| Elmind Capital, LP | $18 180 435 | 525 750 | 0,82% | Actions |
| Balyasny Asset Management L.P. | $18 130 363 | 524 302 | 0,81% | Actions |
| DV EQUITIES, LLC | $16 685 680 | 482 524 | 0,75% | Actions |
| D. E. Shaw & Co., Inc. | $16 301 081 | 471 402 | 0,73% | Actions |
| Octagon Capital Advisors LP | $15 793 412 | 456 721 | 0,71% | Actions |
| MILLENNIUM MANAGEMENT LLC | $14 779 596 | 427 403 | 0,66% | Actions |
| Alyeska Investment Group, L.P. | $14 068 147 | 406 829 | 0,63% | Actions |
| Eversept Partners, LP | $13 361 124 | 386 383 | 0,60% | Actions |
| Ikarian Capital, LLC | $10 680 241 | 308 856 | 0,48% | Actions |
| Tetragon Partners GP Ltd | $10 222 782 | 295 627 | 0,46% | Actions |
| UBS Group AG | $8 810 638 | 254 790 | 0,40% | Actions |
| CITADEL ADVISORS LLC | $8 360 925 | 241 785 | 0,38% | Actions |
| EcoR1 Capital, LLC | $8 126 300 | 235 000 | 0,37% | Actions |
| TWO SIGMA INVESTMENTS, LP | $7 491 411 | 216 640 | 0,34% | Actions |
| ORBIMED ADVISORS LLC | $7 102 732 | 205 400 | 0,32% | Actions |
| Walleye Capital LLC | $6 930 489 | 200 419 | 0,31% | Actions |
| Kalehua Capital Management LLC | $6 873 536 | 198 772 | 0,31% | Actions |
| JANE STREET GROUP, LLC | $6 226 579 | 180 063 | 0,28% | Actions |
| STATE STREET CORP | $5 831 260 | 168 631 | 0,26% | Actions |
| Cinctive Capital Management LP | $5 571 288 | 161 113 | 0,25% | Actions |
| HighVista Strategies LLC | $5 549 882 | 160 494 | 0,25% | Actions |
| GOLDMAN SACHS GROUP INC | $5 186 240 | 149 978 | 0,23% | Actions |
| Qube Research & Technologies Ltd | $4 836 013 | 139 850 | 0,22% | Actions |
| BANK OF AMERICA CORP /DE/ | $4 800 050 | 138 810 | 0,22% | Actions |
| Trexquant Investment LP | $4 713 427 | 136 305 | 0,21% | Actions |
| XTX Topco Ltd | $3 795 501 | 109 760 | 0,17% | Actions |
| NEXTBio Capital Management LP | $3 736 542 | 108 055 | 0,17% | Actions |
| ADAR1 Capital Management, LLC | $3 649 158 | 105 528 | 0,16% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $3 554 582 | 102 793 | 0,16% | Actions |
| MORGAN STANLEY | $3 365 879 | 97 336 | 0,15% | Actions |
| LAZARD ASSET MANAGEMENT LLC | $3 212 102 | 92 889 | 0,14% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $3 108 722 | 89 912 | 0,14% | Actions |
| NORTHERN TRUST CORP | $2 862 602 | 82 782 | 0,13% | Actions |
| STEMPOINT CAPITAL LP | $2 797 764 | 80 907 | 0,13% | Actions |
| TWO SIGMA ADVISERS, LP | $2 486 400 | 89 600 | 0,11% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $2 193 500 | 77 646 | 0,10% | Actions |
| DEUTSCHE BANK AG\ | $1 848 958 | 53 469 | 0,08% | Actions |
| Amundi | $1 727 064 | 49 944 | 0,08% | Actions |
| Squarepoint Ops LLC | $1 543 271 | 44 629 | 0,07% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $1 521 555 | 44 001 | 0,07% | Actions |
| Y-Intercept (Hong Kong) Ltd | $1 380 918 | 39 934 | 0,06% | Actions |
| Atom Investors LP | $1 365 288 | 39 482 | 0,06% | Actions |
| Swiss National Bank | $1 360 965 | 39 357 | 0,06% | Actions |
| TD Asset Management Inc | $1 329 878 | 38 458 | 0,06% | Actions |
| JANE STREET GROUP, LLC | $1 310 582 | 37 900 | 0,06% | Option de vente |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 186 094 | 34 300 | 0,05% | Option de vente |
| VOYA INVESTMENT MANAGEMENT LLC | $1 166 556 | 33 735 | 0,05% | Actions |
| SummitTX Capital, L.P. | $1 153 381 | 33 354 | 0,05% | Actions |
| Engineers Gate Manager LP | $1 143 180 | 33 059 | 0,05% | Actions |
| Aquatic Capital Management LLC | $1 045 111 | 30 223 | 0,05% | Actions |
| Birchview Capital, LP | $1 032 109 | 29 847 | 0,05% | Actions |
| DIADEMA PARTNERS LP | $1 013 920 | 29 321 | 0,05% | Actions |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $1 013 644 | 29 313 | 0,05% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $817 679 | 23 646 | 0,04% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $799 490 | 23 120 | 0,04% | Actions |
| Palumbo Wealth Management LLC | $726 319 | 21 004 | 0,03% | Actions |
| BARCLAYS PLC | $715 875 | 20 702 | 0,03% | Actions |
| Legal & General Group Plc | $712 763 | 20 612 | 0,03% | Actions |
| JPMORGAN CHASE & CO | $693 055 | 19 967 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $629 425 | 18 202 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $594 776 | 17 200 | 0,03% | Option d'achat |
| VANGUARD GROUP INC | $535 853 | 19 310 | 0,02% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $520 775 | 15 060 | 0,02% | Actions |
| PSP Research LLC | $518 700 | 15 000 | 0,02% | Actions |
| China Universal Asset Management Co., Ltd. | $508 983 | 14 719 | 0,02% | Actions |
| ExodusPoint Capital Management, LP | $496 880 | 14 369 | 0,02% | Actions |
| OpenArc Corporate Advisory, LLC | $470 115 | 13 595 | 0,02% | Actions |
| TUDOR INVESTMENT CORP ET AL | $454 623 | 13 147 | 0,02% | Actions |
| Nuveen, LLC | $437 575 | 12 654 | 0,02% | Actions |
| OCCUDO QUANTITATIVE STRATEGIES LP | $393 002 | 11 365 | 0,02% | Actions |
| Virtus Investment Advisers, LLC | $368 312 | 10 651 | 0,02% | Actions |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $311 220 | 9 000 | 0,01% | Actions |
| CITADEL ADVISORS LLC | $297 388 | 8 600 | 0,01% | Option de vente |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $291 025 | 8 416 | 0,01% | Actions |
| Cubist Systematic Strategies, LLC | $290 392 | 11 639 | 0,01% | Actions |
| Police & Firemen's Retirement System of New Jersey | $284 905 | 8 239 | 0,01% | Actions |
| Persistent Asset Partners Ltd | $273 320 | 7 904 | 0,01% | Actions |
| ALLIANCEBERNSTEIN L.P. | $253 685 | 8 980 | 0,01% | Actions |
| ALGERT GLOBAL LLC | $237 910 | 6 880 | 0,01% | Actions |
| Vanguard Investments Australia, Ltd. | $210 558 | 6 089 | 0,01% | Actions |
| KLP KAPITALFORVALTNING AS | $200 564 | 5 800 | 0,01% | Actions |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $196 034 | 5 669 | 0,01% | Actions |
| BARCLAYS PLC | $172 900 | 5 000 | 0,01% | Option d'achat |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $157 719 | 4 561 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $108 063 | 3 125 | 0,00% | Actions |
| CoreCap Advisors, LLC | $93 366 | 2 700 | 0,00% | Actions |
| CITIGROUP INC | $79 672 | 2 304 | 0,00% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $59 754 | 1 728 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $46 960 | 1 358 | 0,00% | Actions |
| Quantbot Technologies LP | $41 081 | 1 188 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $23 376 | 676 | 0,00% | Actions |
| SIMPLEX TRADING, LLC | $21 577 | 624 | 0,00% | Actions |
| 1620 INVESTMENT ADVISORS, INC. | $17 982 | 520 | 0,00% | Actions |
| WELLS FARGO & COMPANY/MN | $15 561 | 450 | 0,00% | Actions |
| State of Wyoming | $12 829 | 371 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $12 389 | 358 270 | 0,00% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $11 377 | 329 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $7 000 | 214 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $5 706 | 165 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $4 011 | 116 | 0,00% | Actions |
| HRT FINANCIAL LP | $2 122 | 61 389 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $1 902 | 55 | 0,00% | Actions |
| GSA CAPITAL PARTNERS LLP | $558 | 16 148 | 0,00% | Actions |
| Bare Financial Services, Inc | $484 | 14 | 0,00% | Actions |
| Quarry LP | $242 | 7 | 0,00% | Actions |
| Larson Financial Group LLC | $207 | 6 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $35 | 1 | 0,00% | Actions |
| Point72 Asia (Singapore) Pte. Ltd. | $25 | 1 | 0,00% | Actions |
| Centerpoint Advisors, LLC | $3 | 100 | 0,00% | Actions |