PRTA Prothena Corporation plc - Ordinary Shares
$9,19
Prix · Aoû 19, 2026
Données fondamentales au Aoû 6, 2026
Fourchette 52 semaines
$8–$12
36% of range
Note des analystes
BUY
12 analysts
Objectif de cours
$21
+133% upside
P/E (TTM)
-2.0
ROE
-63.6%
Marge nette
-2520.6%
PRTA Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$9.19
Capitalisation Boursière
$495M
P/E (TTM)
-2.0
BPA (TTM)
$-4.53
Revenus (TTM)
$10M
Rendement div.
—
ROE
-63.6%
Dette/Capitaux propres
—
Fourchette 52 semaines
$8 – $12
PRTA Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
$10M
2016-12-31
→
2025-12-31
BPA
$-4.53
2019-12-31
→
2025-12-31
Flux de trésorerie libre
—
Marges
-2520.6%
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
PRTA
Médiane des pairs
P/E (TTM)
-2.0
55.9
P/S (TTM)
51.1
5.5
P/B
1.8
1.8
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
PRTA
Médiane des pairs
Operating Margin (Marge d'exploitation)
-2216.4%
—
Net Profit Margin (Marge nette)
-2520.6%
-14.2%
ROA
-55.9%
-4.2%
ROE
-63.6%
-6.0%
ROIC
-93.0%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
PRTA
Médiane des pairs
Current Ratio (Ratio de liquidité)
7.7
3.7
Quick Ratio (Ratio de liquidité réduite)
7.5
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
PRTA
Médiane des pairs
Revenue YoY (Chiffre d'affaires YoY)
-92.8%
—
Revenue CAGR 3Y (CAGR du chiffre d'affaires 3 ans)
-43.6%
—
Revenue CAGR 5Y (CAGR du chiffre d'affaires 5 ans)
62.6%
—
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
PRTA
Médiane des pairs
PRTA Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
12 analystes
- Achat fort 2 16,7%
- Achat 6 50,0%
- Conserver 3 25,0%
- Vente 1 8,3%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
5 analystes · 2026-08-15
Médiane
$20.00
Maintenant
$9.19
Bas
$8.00
Haut
$36.00
Objectif médian
$20.00
+117,6%
Objectif moyen
$21.40
+132,9%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
0.11%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.36 | $-0.40 | 0.04% |
| 31 mars 2026 | $0.61 | $-0.36 | 0.97% |
| 31 décembre 2025 | $-0.40 | $-0.57 | 0.17% |
| 30 septembre 2025 | $-0.68 | $-0.70 | 0.02% |
| 30 juin 2025 | $-1.73 | $-1.34 | -0.39% |
| 31 mars 2025 | $-1.12 | $-0.99 | -0.13% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| PRTA | $514M | -2.1 | -92.8% | -2520.6% | -63.6% | — |
| ALKS | $4.63B | 19.6 | -5.2% | 16.4% | 14.0% | — |
| AMRN | $5.81B | -155.1 | -6.6% | -18.2% | -8.4% | 56.6% |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $10M | $135M | $91M | $54M | $201M | $853.0K | $814.0K | $955.0K | $28M | $1M | $2M | $51M | |
| R&D Expense | $135M | $223M | $221M | $136M | $82M | $75M | $51M | $101M | $135M | $120M | $58M | $38M | |
| SG&A Expense | $59M | $67M | $62M | $50M | $46M | $39M | $36M | $42M | $48M | $41M | $23M | $19M | |
| Operating Expenses | $224M | $290M | $282M | $185M | $129M | $114M | $87M | $160M | $183M | $161M | $82M | $58M | |
| Operating Income | $-215M | $-155M | $-191M | $-132M | $72M | $-113M | $-86M | $-159M | $-155M | $-160M | $-80M | $-7M | |
| Other Non-op | $-328.0K | $-185.0K | $-458.0K | $-397.0K | $-96.0K | $-62.0K | $196.0K | $48.0K | $-2M | $15.0K | $-170.0K | $231.0K | |
| Pretax Income | $-201M | $-129M | $-160M | $-126M | $72M | $-111M | $-77M | $-156M | $-158M | $-159M | $-80M | $-6M | |
| Income Tax | $43M | $-7M | $-13M | $-9M | $5M | $-283.0K | $379.0K | $-470.0K | $-4M | $1M | $701.0K | $811.0K | |
| Net Income | $-244M | $-122M | $-147M | $-117M | $67M | $-111M | $-78M | $-156M | $-153M | $-160M | $-81M | $-7M | |
| EPS (Basic) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.51 | $-2.78 | $-1.95 | · | · | · | · | · | |
| EPS (Diluted) | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 | $-2.78 | $-1.95 | · | · | · | · | · | |
| Shares (Basic) | 53,829,000 | 53,772,000 | 53,216,000 | 47,369,000 | 44,228,000 | 39,915,000 | 39,882,000 | · | · | · | · | · | |
| Shares (Diluted) | 53,829,000 | 53,772,000 | 53,216,000 | 47,369,000 | 48,464,000 | 39,915,000 | 39,882,000 | · | · | · | · | · | |
| EBITDA | $-214M | $-154M | $-190M | $-131M | $73M | $-111M | $-84M | $-156M | $-152M | $-157M | $-79M | $-6M |
Bilan 21
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $308M | $471M | $619M | $710M | $579M | $295M | $376M | $428M | $418M | $387M | $371M | $294M | |
| Receivables | · | $0 | $5M | $0 | $0 | $15.0K | $68.0K | $2.0K | $240.0K | $178.0K | $509.0K | $2M | |
| Prepaid Expense | $8M | $14M | $14M | $9M | $6M | $3M | $3M | $4M | $8M | $4M | $6M | $4M | |
| Other Current Assets | · | · | · | · | · | · | $3M | $4M | · | · | · | · | |
| Current Assets | $315M | $485M | $639M | $719M | $585M | $299M | $378M | $431M | $426M | $391M | $377M | $299M | |
| PP&E (Net) | $2M | $3M | $4M | $2M | $2M | $3M | $4M | $53M | $55M | $56M | $4M | $3M | |
| PP&E (Gross) | $9M | $11M | $11M | $13M | $12M | $12M | $12M | $63M | $63M | $64M | $9M | $8M | |
| Accum. Depreciation | $7M | $8M | $7M | $11M | $10M | $9M | $8M | $11M | $8M | $8M | $5M | $5M | |
| Other Non-current Assets | $482.0K | $4M | $6M | $11M | $2M | $333.0K | $1M | $813.0K | $3M | $2M | $1M | $0 | |
| Total Assets | $327M | $547M | $696M | $758M | $609M | $333M | $419M | $499M | $496M | $460M | $385M | $304M | |
| Accounts Payable | $6M | $8M | $25M | $9M | $4M | $4M | $1M | $1M | $14M | $13M | $5M | $5M | |
| Current Liabilities | $41M | $49M | $57M | $50M | $33M | $26M | $18M | $15M | $37M | $41M | $22M | $12M | |
| Capital Leases | $5M | $8M | $11M | $0 | $6M | $12M | $18M | $0 | · | · | · | · | |
| Other Non-current Liabilities | · | · | $0 | $553.0K | $553.0K | $553.0K | $553.0K | $553.0K | $0 | $0 | $126.0K | $0 | |
| Total Liabilities | $46M | $60M | $135M | $136M | $143M | $149M | $146M | $176M | $89M | $95M | $25M | $14M | |
| Common Stock | $538.0K | $538.0K | $537.0K | $521.0K | $466.0K | $399.0K | $399.0K | $399.0K | $385.0K | $348.0K | $317.0K | $274.0K | |
| Paid-in Capital | $1.63B | $1.59B | $1.54B | $1.45B | $1.18B | $967M | $944M | $921M | $849M | $654M | $489M | $338M | |
| Retained Earnings | $-1.35B | $-1.10B | $-980M | $-833M | $-716M | $-783M | $-672M | $-598M | $-442M | $-289M | $-129M | $-48M | |
| Stockholders' Equity | $280M | $487M | $561M | $622M | $466M | $184M | $273M | $323M | $407M | $365M | $361M | $290M | |
| Liabilities + Equity | $327M | $547M | $696M | $758M | $609M | $333M | $419M | $499M | $496M | $460M | $385M | $304M | |
| Shares Outstanding | 53,832,982 | 53,826,982 | 53,682,117 | 52,103,608 | 46,660,294 | 39,921,413 | 39,898,561 | 39,863,711 | 38,482,764 | 34,752,116 | 31,744,102 | 27,388,005 |
Flux de trésorerie 12
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $895.0K | $893.0K | $928.0K | $744.0K | $1M | $2M | $2M | $3M | $3M | $2M | $806.0K | $743.0K | |
| Stock-based Comp | $38M | $46M | $41M | $31M | $25M | $22M | $24M | $27M | $27M | $25M | $10M | $6M | |
| Deferred Tax | $43M | $-9M | $-16M | $-11M | $5M | $-2M | $-1M | $-2M | $-2M | $-3M | $-963.0K | $-1M | |
| Restructuring | · | · | · | · | · | · | $-61.0K | $15M | · | · | · | · | |
| Other Non-cash | $-1M | $-65M | $-13M | $-13M | $-5M | $9M | $808.0K | $99M | $-6M | $19M | $8M | $1M | |
| Operating Cash Flow | $-164M | $-150M | $-134M | $-109M | $93M | $-80M | $-53M | $-28M | $-131M | $-116M | $-59M | $-683.0K | |
| Investing Cash Flow | $-138.0K | $-298.0K | $-3M | $-464.0K | $-575.0K | $-196.0K | $-547.0K | $-2M | $-4M | $-17M | $-1M | $-499.0K | |
| Stock Issued | · | · | · | · | $78M | $0 | $0 | $0 | $150M | $129M | $131M | $117M | |
| Net Stock Activity | · | · | · | · | $78M | · | $0 | $0 | $150M | $129M | $131M | $117M | |
| Financing Cash Flow | $-139.0K | $2M | $45M | $241M | $190M | $215.0K | $228.0K | $40M | $165M | $153M | $137M | $118M | |
| Net Change in Cash | · | · | · | · | · | · | · | · | · | · | $77M | $117M | |
| Taxes Paid | $931.0K | $3M | $2M | $3M | $580.0K | $1M | $2M | $-995.0K | $294.0K | · | · | · |
Rentabilité 7
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2216.4% | -114.4% | -209.1% | -244.1% | 35.9% | -13216.2% | -10527.9% | -16634.0% | -564.2% | -15121.8% | -4974.3% | -13.1% | |
| Net Margin | -2520.6% | -90.5% | -160.9% | -217.0% | 33.4% | -13029.8% | -9542.6% | -16297.9% | -556.8% | -15176.1% | -5016.3% | -14.1% | |
| Pretax Margin | -2073.8% | -95.4% | -175.6% | -233.0% | 35.9% | -13063.0% | -9496.1% | -16347.1% | -572.7% | -15067.7% | -4972.7% | -12.5% | |
| EBITDA Margin | -2207.2% | -113.7% | -208.1% | -242.7% | 36.4% | -13038.7% | -10335.8% | -16297.3% | -553.0% | -14891.7% | -4924.1% | -11.6% | |
| ROA | -55.9% | -19.7% | -20.2% | -17.1% | 14.2% | -29.5% | -16.9% | -31.3% | -32.0% | -37.9% | -23.4% | -2.9% | |
| ROE | -63.6% | -23.3% | -24.9% | -21.5% | 20.6% | -48.6% | -26.1% | -42.6% | -39.7% | -44.1% | -24.8% | -3.1% | |
| ROIC | -93.0% | -30.1% | -31.2% | -19.7% | 14.4% | -61.1% | -31.6% | -49.0% | -37.1% | -44.0% | -22.4% | -2.6% |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.7 | 10.0 | 11.2 | 14.3 | 17.5 | 11.6 | 21.4 | 28.9 | 11.4 | 9.5 | 17.0 | 24.9 | |
| Quick Ratio | 7.5 | 9.7 | 11.0 | 14.2 | 17.3 | 11.4 | 21.2 | 28.7 | 11.2 | 9.4 | 16.7 | 24.5 |
Efficacité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | 0.1 | 0.1 | 0.4 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | 0.2 | |
| Receivables Turnover | · | 52.4 | 35.4 | · | 26743.6 | 20.6 | 23.3 | 7.9 | 131.7 | 3.1 | 1.4 | 58.8 |
Taux de croissance 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -92.8% | 47.9% | 69.5% | -73.1% | 23414.3% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -43.6% | -12.3% | 374.9% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 62.6% | · | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 9
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $10M | $135M | $91M | $54M | $201M | $853.0K | $814.0K | $955.0K | $28M | $1M | $2M | $51M | |
| Net Income TTM | $-244M | $-122M | $-147M | $-117M | $67M | $-111M | $-78M | $-156M | $-153M | $-160M | $-81M | $-7M | |
| Market Cap | $514M | $746M | $1.95B | $3.14B | $2.31B | $479M | $632M | $411M | $1.44B | $1.71B | $2.16B | $569M | |
| P/E | -2.1 | -6.1 | -13.2 | -24.4 | 35.8 | -4.3 | -8.1 | -2.6 | -9.2 | -10.6 | -25.9 | -173.0 | |
| P/S | 53.1 | 5.5 | 21.4 | 58.2 | 11.5 | 562.1 | 775.9 | 429.9 | 52.4 | 1620.3 | 1345.4 | 11.2 | |
| P/B | 1.8 | 1.5 | 3.5 | 5.0 | 4.9 | 2.6 | 2.3 | 1.3 | 3.5 | 4.7 | 6.0 | 2.0 | |
| P / Tangible Book | 1.8 | 1.5 | 3.5 | 5.0 | 4.9 | 2.6 | · | · | · | · | · | · | |
| P / Cash Flow | -3.1 | -5.0 | -14.6 | -28.8 | 24.9 | -6.0 | -11.9 | -14.5 | -11.0 | -14.6 | -34.6 | -832.5 | |
| Earnings Yield | -47.4% | -16.4% | -7.6% | -4.1% | 2.8% | -23.2% | -12.3% | -38.2% | -10.8% | -9.5% | -3.9% | -0.58% |
Compte de résultat 14
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1M | $51M | $21.0K | $2M | $4M | $3M | $2M | $970.0K | $132M | $50.0K | $316.0K | $85M | $4M | $2M | $50M | $2M | |
| R&D Expense | $9M | $13M | $15M | $29M | $41M | $51M | $50M | $51M | $58M | $64M | $62M | $58M | $56M | $45M | $37M | $40M | |
| SG&A Expense | $11M | $13M | $13M | $13M | $16M | $18M | $17M | $17M | $16M | $17M | $17M | $17M | $15M | $14M | $13M | $12M | |
| Operating Expenses | $22M | $21M | $24M | $43M | $89M | $68M | $67M | $67M | $74M | $82M | $79M | $75M | $71M | $58M | $50M | $52M | |
| Operating Income | $-21M | $30M | $-24M | $-40M | $-85M | $-66M | $-65M | $-67M | $58M | $-82M | $-79M | $10M | $-67M | $-56M | $-72.0K | $-50M | |
| Other Non-op | $-33.0K | $271.0K | $-22.0K | $-23.0K | $-143.0K | $-140.0K | $9.0K | $-66.0K | $-51.0K | $-77.0K | $-205.0K | $-15.0K | $-97.0K | $-141.0K | $-327.0K | $2.0K | |
| Pretax Income | $-19M | $33M | $-22M | $-37M | $-81M | $-61M | $-60M | $-60M | $65M | $-74M | $-71M | $19M | $-59M | $-50M | $3M | $-48M | |
| Income Tax | $2.0K | $1.0K | $10.0K | $-371.0K | $45M | $-1M | $-2M | $-835.0K | $-2M | $-2M | $-3M | $-3M | $-4M | $-3M | $-3M | $-3M | |
| Net Income | $-19M | $33M | $-22M | $-37M | $-126M | $-60M | $-58M | $-59M | $67M | $-72M | $-67M | $22M | $-55M | $-47M | $6M | $-46M | |
| EPS (Basic) | $-0.36 | $0.61 | $-0.39 | $-0.68 | $-2.34 | $-1.12 | $-1.07 | $-1.10 | $1.24 | $-1.34 | $-1.25 | $0.41 | $-1.03 | $-0.89 | $0.16 | $-0.97 | |
| EPS (Diluted) | $-0.36 | $0.60 | $-0.39 | $-0.68 | $-2.34 | $-1.12 | $-1.05 | $-1.10 | $1.22 | $-1.34 | $-1.22 | $0.38 | $-1.03 | $-0.89 | $0.16 | $-0.97 | |
| Shares (Basic) | 52,145,000 | 53,708,000 | -107,655,000 | 53,830,000 | 53,827,000 | 53,827,000 | -107,499,000 | 53,790,000 | 53,767,000 | 53,714,000 | -105,965,000 | 53,559,000 | 53,121,000 | 52,501,000 | -93,126,000 | 46,986,000 | |
| Shares (Diluted) | 52,145,000 | 54,109,000 | -107,655,000 | 53,830,000 | 53,827,000 | 53,827,000 | -108,775,000 | 53,790,000 | 55,043,000 | 53,714,000 | -110,410,000 | 58,004,000 | 53,121,000 | 52,501,000 | -93,126,000 | 46,986,000 | |
| EBITDA | $-21M | $30M | · | $-40M | $-85M | $-65M | · | $-67M | $58M | $-81M | · | $10M | $-67M | $-56M | · | $-50M |
Bilan 20
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $288M | $329M | $308M | $331M | $371M | $418M | $471M | $519M | $564M | $547M | $619M | $671M | $659M | $686M | $710M | $496M | |
| Receivables | · | · | · | · | · | · | · | $0 | $0 | $0 | · | $5M | $524.0K | · | · | · | |
| Prepaid Expense | $4M | $10M | $8M | $9M | $14M | $18M | $14M | $16M | $22M | $18M | · | $13M | $16M | $14M | · | $29M | |
| Current Assets | $292M | $339M | $315M | $340M | $385M | $436M | $485M | $535M | $586M | $566M | · | $691M | $677M | $700M | · | $525M | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $4M | · | $2M | $2M | $2M | · | $2M | |
| PP&E (Gross) | $9M | $9M | $9M | $9M | $10M | $11M | $11M | $11M | $11M | $11M | · | $14M | $14M | $13M | · | $13M | |
| Accum. Depreciation | $7M | $7M | $7M | $7M | $7M | $8M | $8M | $8M | $8M | $8M | · | $12M | $12M | $11M | · | $11M | |
| Other Non-current Assets | $482.0K | $482.0K | $482.0K | $482.0K | $478.0K | $494.0K | $4M | $4M | $4M | $4M | · | $10M | $11M | $11M | · | $4M | |
| Total Assets | $303M | $350M | $327M | $353M | $399M | $495M | $547M | $595M | $646M | $623M | · | $747M | $721M | $742M | · | $554M | |
| Accounts Payable | $2M | $4M | $6M | $11M | $12M | $16M | $8M | $10M | $9M | $14M | · | $19M | $14M | $13M | · | $10M | |
| Current Liabilities | $12M | $33M | $41M | $51M | $68M | $48M | $49M | $46M | $47M | $43M | · | $53M | $72M | $49M | · | $51M | |
| Capital Leases | $4M | $5M | $5M | $6M | $7M | $8M | $8M | $9M | $10M | $10M | · | $9M | · | · | · | $2M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | · | $553.0K | |
| Total Liabilities | $16M | $37M | $46M | $58M | $75M | $58M | $60M | $61M | $64M | $121M | · | $130M | $139M | $134M | · | $150M | |
| Common Stock | $517.0K | $530.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $538.0K | $537.0K | · | $536.0K | $535.0K | $527.0K | · | $479.0K | |
| Paid-in Capital | $1.62B | $1.63B | $1.63B | $1.62B | $1.61B | $1.60B | $1.59B | $1.58B | $1.57B | $1.55B | · | $1.53B | $1.52B | $1.49B | · | $1.24B | |
| Retained Earnings | $-1.33B | $-1.31B | $-1.35B | $-1.32B | $-1.29B | $-1.16B | $-1.10B | $-1.04B | $-985M | $-1.05B | · | $-913M | $-934M | $-880M | · | $-839M | |
| Stockholders' Equity | $287M | $313M | $280M | $295M | $324M | $438M | $487M | $534M | $582M | $502M | · | $617M | $582M | $607M | · | $405M | |
| Liabilities + Equity | $303M | $350M | $327M | $353M | $399M | $495M | $547M | $595M | $646M | $623M | · | $747M | $721M | $742M | · | $554M | |
| Shares Outstanding | 51,744,327 | 53,077,225 | 53,832,982 | 53,829,982 | 53,826,982 | 53,826,982 | 53,826,982 | 53,808,732 | 53,771,845 | 53,720,455 | · | 53,638,615 | 53,493,467 | 52,678,178 | · | 47,885,755 |
Flux de trésorerie 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $197.0K | $184.0K | $218.0K | $229.0K | $225.0K | $223.0K | $221.0K | $226.0K | $231.0K | $215.0K | $276.0K | $229.0K | $222.0K | $201.0K | $196.0K | $182.0K | |
| Stock-based Comp | $8M | $7M | $7M | $7M | $12M | $11M | $11M | $11M | $12M | $12M | $11M | $11M | $10M | $9M | $7M | $8M | |
| Restructuring | · | $-4M | · | $500.0K | $33M | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-cash | · | $-11M | · | · | · | $-4M | · | · | · | $-13M | · | · | · | $-10M | · | · | |
| Operating Cash Flow | $-25M | $29M | $-23M | $-41M | $-46M | $-53M | $-48M | $-45M | $16M | $-73M | $-51M | $10M | $-45M | $-47M | $-5M | $-31M | |
| Investing Cash Flow | $-652.0K | $0 | $0 | $-10.0K | $-86.0K | $-42.0K | $-43.0K | $-9.0K | $-143.0K | $-103.0K | $-2M | $-442.0K | $-771.0K | $-48.0K | $-151.0K | $-130.0K | |
| Financing Cash Flow | $-16M | $-7M | $0 | $-17.0K | $-74.0K | $-48.0K | $-59.0K | $333.0K | $444.0K | $836.0K | $483.0K | $3M | $19M | $23M | $221M | $18M | |
| Taxes Paid | $-616.0K | $0 | $-10.0K | $2.0K | $939.0K | $0 | $760.0K | $836.0K | $2M | $20.0K | $1M | $50.0K | $334.0K | $0 | $285.0K | $751.0K |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -2089.2% | 58.8% | · | -1666.3% | -1914.4% | -2319.0% | · | -6857.0% | 44.2% | -163056.0% | · | 12.2% | -1654.7% | -2596.8% | · | -3317.9% | |
| Net Margin | -1839.9% | 64.0% | · | -1513.1% | -2845.4% | -2128.5% | · | -6082.6% | 50.7% | -144478.0% | · | 25.8% | -1358.4% | -2160.6% | · | -3016.7% | |
| Pretax Margin | -1839.7% | 64.1% | · | -1528.5% | -1831.8% | -2170.2% | · | -6168.7% | 49.1% | -148880.0% | · | 22.2% | -1465.6% | -2294.9% | · | -3191.6% | |
| EBITDA Margin | -2089.2% | 59.2% | · | -1666.3% | -1914.4% | -2311.1% | · | -6857.0% | 44.2% | -162626.0% | · | 12.2% | -1654.7% | -2587.5% | · | -3317.9% | |
| ROA | -5.3% | 7.7% | · | -7.7% | -24.1% | -10.8% | · | -8.8% | 9.8% | -10.6% | · | 3.4% | -8.6% | -7.1% | · | -7.7% | |
| ROE | -6.1% | 8.7% | · | -8.8% | -27.8% | -12.8% | · | -10.2% | 11.5% | -13.0% | · | 4.3% | -11.0% | -9.0% | · | -10.2% | |
| ROIC | -7.4% | 9.6% | · | -13.5% | -40.5% | -14.7% | · | -12.3% | 10.3% | -15.8% | · | 1.9% | -10.6% | -8.7% | · | -11.8% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 25.0 | 10.4 | · | 6.6 | 5.7 | 9.0 | · | 11.5 | 12.5 | 13.1 | · | 12.9 | 9.5 | 14.3 | · | 10.4 | |
| Quick Ratio | 24.7 | 10.1 | · | 6.4 | 5.5 | 8.6 | · | 11.2 | 12.1 | 12.6 | · | 12.7 | 9.2 | 14.0 | · | 9.8 |
Efficacité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.2 | 0.0 | · | 0.1 | 0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | 0.4 | 503.9 | 100.0 | · | 32.4 | 15.3 | · | · | · |
Valorisation (TTM) 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $59M | $61M | · | $11M | $140M | $136M | · | $218M | $221M | $91M | · | $93M | $9M | $6M | · | $143M | |
| Net Income TTM | $-148M | $-190M | · | $-282M | $-178M | $-125M | · | $-42M | $-38M | $-152M | · | $-125M | $-188M | $-170M | · | $-14M | |
| Market Cap | $507M | $516M | · | $525M | $327M | $666M | · | $900M | $1.11B | $1.33B | · | $2.59B | $3.65B | $2.55B | · | $2.90B | |
| P/E | -3.5 | -2.7 | · | -1.9 | -1.8 | -5.3 | · | -19.9 | -26.8 | -8.6 | · | -19.2 | -18.1 | -13.8 | · | -121.3 | |
| P/S | 8.6 | 8.5 | · | 49.4 | 2.3 | 4.9 | · | 4.1 | 5.0 | 14.6 | · | 28.0 | 405.1 | 415.1 | · | 20.3 | |
| P/B | 1.8 | 1.7 | · | 1.8 | 1.0 | 1.5 | · | 1.7 | 1.9 | 2.6 | · | 4.2 | 6.3 | 4.2 | · | 7.2 | |
| P / Tangible Book | 1.8 | 1.7 | · | 1.8 | 1.0 | 1.5 | · | 1.7 | 1.9 | 2.6 | · | 4.2 | 6.3 | 4.2 | · | 7.2 | |
| P / Cash Flow | · | 17.9 | · | · | · | -12.5 | · | · | · | -18.2 | · | · | · | -53.8 | · | · | |
| Earnings Yield | -28.4% | -36.4% | · | -53.7% | -55.0% | -18.9% | · | -5.0% | -3.7% | -11.6% | · | -5.2% | -5.5% | -7.3% | · | -0.82% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $10M | $135M | $91M | $54M | $201M |
| Marge d'exploitation % | -2216.4% | -114.4% | -209.1% | -244.1% | 35.9% |
| Résultat net | $-244M | $-122M | $-147M | $-117M | $67M |
| BPA dilué | $-4.53 | $-2.27 | $-2.76 | $-2.47 | $1.38 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 7.7 | 10.0 | 11.2 | 14.3 | 17.5 |
| Ratio de liquidité réduite | 7.5 | 9.7 | 11.0 | 14.2 | 17.3 |
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Détenteurs institutionnels (13F) 210 déclarants · $338.3M total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 35 (+8 vs T. préc.) | 21 (-1 vs T. préc.) | 53 (-11 vs T. préc.) | 57 (+4 vs T. préc.) | +4.9M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Rubric Capital Management LP | $48 950 000 | 5 000 000 | 14,47% | Actions |
| FMR LLC | $37 822 108 | 3 863 341 | 11,18% | Actions |
| STATE STREET CORP | $23 431 621 | 2 393 424 | 6,93% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $16 166 158 | 1 651 293 | 4,78% | Actions |
| D. E. Shaw & Co., Inc. | $15 776 164 | 1 611 457 | 4,66% | Actions |
| ADAR1 Capital Management, LLC | $15 218 898 | 1 554 535 | 4,50% | Actions |
| TWO SIGMA INVESTMENTS, LP | $12 384 223 | 1 264 987 | 3,66% | Actions |
| Palo Alto Investors LP | $11 191 487 | 1 143 155 | 3,31% | Actions |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $9 457 023 | 965 988 | 2,80% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $9 448 487 | 964 846 | 2,79% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $8 269 574 | 844 696 | 2,44% | Actions |
| GOLDMAN SACHS GROUP INC | $7 812 254 | 797 983 | 2,31% | Actions |
| Qube Research & Technologies Ltd | $7 745 545 | 791 169 | 2,29% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $6 829 651 | 697 615 | 2,02% | Actions |
| Man Group plc | $6 638 756 | 678 116 | 1,96% | Actions |
| Mariner, LLC | $6 119 684 | 625 095 | 1,81% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $4 698 662 | 479 945 | 1,39% | Actions |
| Birchview Capital, LP | $4 395 896 | 449 019 | 1,30% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4 120 611 | 420 900 | 1,22% | Option d'achat |
| Rangeley Capital, LLC | $4 085 073 | 417 270 | 1,21% | Actions |
| TWO SIGMA ADVISERS, LP | $4 081 670 | 427 400 | 1,21% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3 484 222 | 355 896 | 1,03% | Actions |
| CITADEL ADVISORS LLC | $3 316 950 | 338 810 | 0,98% | Actions |
| MONIMUS CAPITAL MANAGEMENT, LP | $3 221 419 | 329 052 | 0,95% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $3 091 711 | 315 803 | 0,91% | Actions |
| BlackRock, Inc. | $2 701 923 | 275 988 | 0,80% | Actions |
| Penbrook Management LLC | $2 660 138 | 271 720 | 0,79% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $2 536 237 | 259 064 | 0,75% | Actions |
| MACKENZIE FINANCIAL CORP | $2 348 611 | 239 899 | 0,69% | Actions |
| Coppell Advisory Solutions LLC | $2 329 573 | 6 | 0,69% | Actions |
| VANGUARD GROUP INC | $2 300 834 | 240 925 | 0,68% | Actions |
| Squarepoint Ops LLC | $2 192 676 | 223 971 | 0,65% | Actions |
| Focused Wealth Management, Inc | $2 030 887 | 207 445 | 0,60% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $1 871 319 | 191 146 | 0,55% | Actions |
| Cubist Systematic Strategies, LLC | $1 863 662 | 190 949 | 0,55% | Actions |
| BANK OF AMERICA CORP /DE/ | $1 734 445 | 177 165 | 0,51% | Actions |
| Quantinno Capital Management LP | $1 550 060 | 158 331 | 0,46% | Actions |
| MILLENNIUM MANAGEMENT LLC | $1 467 521 | 149 900 | 0,43% | Option d'achat |
| DIADEMA PARTNERS LP | $1 463 429 | 149 482 | 0,43% | Actions |
| CITADEL ADVISORS LLC | $1 393 117 | 142 300 | 0,41% | Option de vente |
| FEDERATED HERMES, INC. | $1 384 766 | 141 447 | 0,41% | Actions |
| CITADEL ADVISORS LLC | $1 144 451 | 116 900 | 0,34% | Option d'achat |
| JANE STREET GROUP, LLC | $1 014 244 | 103 600 | 0,30% | Option d'achat |
| AMERICAN CENTURY COMPANIES INC | $887 405 | 90 644 | 0,26% | Actions |
| AMERIPRISE FINANCIAL INC | $844 779 | 86 290 | 0,25% | Actions |
| XTX Topco Ltd | $839 169 | 85 717 | 0,25% | Actions |
| Susquehanna Portfolio Strategies, LLC | $809 731 | 82 710 | 0,24% | Actions |
| ExodusPoint Capital Management, LP | $803 005 | 82 023 | 0,24% | Actions |
| MARTINGALE ASSET MANAGEMENT L P | $771 452 | 78 800 | 0,23% | Actions |
| Trexquant Investment LP | $751 196 | 76 731 | 0,22% | Actions |
| DCF Advisers, LLC | $717 088 | 73 247 | 0,21% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $688 492 | 70 326 | 0,20% | Actions |
| Duncan Williams Asset Management, LLC | $688 051 | 70 281 | 0,20% | Actions |
| ALLIANCEBERNSTEIN L.P. | $672 789 | 69 217 | 0,20% | Actions |
| Campbell & CO Investment Adviser LLC | $669 098 | 68 345 | 0,20% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $646 140 | 66 000 | 0,19% | Option de vente |
| Assenagon Asset Management S.A. | $614 665 | 62 785 | 0,18% | Actions |
| PINNACLE ASSOCIATES LTD | $567 017 | 57 918 | 0,17% | Actions |
| RHUMBLINE ADVISERS | $547 206 | 55 896 | 0,16% | Actions |
| Schonfeld Strategic Advisors LLC | $492 925 | 50 350 | 0,15% | Actions |
| HSBC HOLDINGS PLC | $492 220 | 49 569 | 0,15% | Actions |
| EDGEWOOD MANAGEMENT LLC | $489 500 | 50 000 | 0,14% | Actions |
| Quinn Opportunity Partners LLC | $489 500 | 50 000 | 0,14% | Actions |
| JANE STREET GROUP, LLC | $465 025 | 47 500 | 0,14% | Option de vente |
| Seven Fleet Capital Management LP | $423 907 | 43 300 | 0,13% | Actions |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $412 727 | 42 158 | 0,12% | Actions |
| Engineers Gate Manager LP | $404 033 | 41 270 | 0,12% | Actions |
| Rafferty Asset Management, LLC | $395 487 | 40 397 | 0,12% | Actions |
| Virtus Investment Advisers, LLC | $388 271 | 39 660 | 0,11% | Actions |
| SHELTON CAPITAL MANAGEMENT | $386 431 | 39 472 | 0,11% | Actions |
| WELLS FARGO & COMPANY/MN | $384 306 | 39 255 | 0,11% | Actions |
| Persistent Asset Partners Ltd | $372 999 | 38 100 | 0,11% | Actions |
| BARCLAYS PLC | $359 195 | 36 690 | 0,11% | Actions |
| WINTON GROUP Ltd | $298 595 | 30 500 | 0,09% | Actions |
| RBF Capital, LLC | $285 868 | 29 200 | 0,08% | Actions |
| GREAT LAKES ADVISORS, LLC | $281 296 | 28 733 | 0,08% | Actions |
| PNC Financial Services Group, Inc. | $276 920 | 28 286 | 0,08% | Actions |
| MetLife Investment Management, LLC | $253 463 | 25 890 | 0,07% | Actions |
| Aquatic Capital Management LLC | $248 852 | 25 419 | 0,07% | Actions |
| Purkiss Capital Advisors LLC | $245 592 | 25 086 | 0,07% | Actions |
| TUDOR INVESTMENT CORP ET AL | $239 317 | 24 445 | 0,07% | Actions |
| CANADA PENSION PLAN INVESTMENT BOARD | $234 960 | 24 000 | 0,07% | Actions |
| ENVESTNET ASSET MANAGEMENT INC | $224 269 | 22 908 | 0,07% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $210 407 | 21 492 | 0,06% | Actions |
| MOGY JOEL R INVESTMENT COUNSEL INC | $203 142 | 20 750 | 0,06% | Actions |
| PROFUND ADVISORS LLC | $201 380 | 20 570 | 0,06% | Actions |
| MORGAN STANLEY | $197 259 | 20 149 | 0,06% | Actions |
| JONES FINANCIAL COMPANIES LLLP | $194 689 | 19 430 | 0,06% | Actions |
| Savant Capital, LLC | $190 192 | 19 503 | 0,06% | Actions |
| Foundation Wealth Management, LLC | $188 322 | 19 236 | 0,06% | Actions |
| Graham Capital Management, L.P. | $181 076 | 18 496 | 0,05% | Actions |
| Vanguard Global Advisers, LLC | $178 658 | 18 249 | 0,05% | Actions |
| STRS OHIO | $175 241 | 17 900 | 0,05% | Actions |
| Invesco Ltd. | $172 980 | 17 669 | 0,05% | Actions |
| Ballentine Partners, LLC | $164 403 | 16 793 | 0,05% | Actions |
| Russell Investments Group, Ltd. | $157 276 | 16 065 | 0,05% | Actions |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $150 629 | 15 386 | 0,04% | Actions |
| Headlands Technologies LLC | $147 604 | 15 077 | 0,04% | Actions |
| CHICAGO TRUST Co NA | $147 408 | 15 057 | 0,04% | Actions |
| Skopos Labs, Inc. | $145 732 | 14 993 | 0,04% | Actions |
Initiés de la société 33 initiés · 20 dirigeants · 12 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Gene G. Kinney | President and CEO | 28 juillet 2026 M | 68 793 | 0 | 0 | $0 |
| Dale B. Schenk | President and CEO | 24 février 2016 A | 14 877 | 0 | 0 | $0 |
| Tran Nguyen | Chief Strategy Officer and CFO | 28 juillet 2026 M | 40 205 | 0 | 0 | $0 |
| Brandon S. Smith | Chief Operating Officer | 28 juillet 2026 M | 52 000 | 0 | 0 | $0 |
| Anne Evans Kingston | Chief Strategy Officer | 29 juillet 2026 S | 55 782 | 0 | 1 | $-64 897 |
| Michael John Isaacs | General Counsel & Company Sec. | 29 juillet 2026 S | 35 745 | 0 | 1 | $-71 029 |
| Chad J. Swanson | Chief Development Officer | 28 juillet 2026 M | 40 733 | 0 | 0 | $0 |
| Wagner M. Zago | Chief Scientific Officer | 28 juillet 2026 M | 34 000 | 0 | 0 | $0 |
| Karin L Walker | Chief Accounting Officer | 28 juillet 2026 M | 10 000 | 0 | 0 | $0 |
| Michael J Malecek | Chief Legal Officer | 3 mars 2026 A | 80 000 | 0 | 0 | $0 |
| David A Ford | Chief People Officer | 5 mars 2025 A | — | 0 | 0 | $0 |
| Carol D. Karp | Chief Regulatory Officer | 5 mars 2025 A | 0 | 0 | 0 | $0 |
| Hideki Garren | Chief Medical Officer | 27 février 2024 A | 0 | 0 | 0 | $0 |
| Radhika Tripuraneni | Chief Development Officer | 23 février 2022 A | — | 0 | 0 | $0 |
| Arthur W Homan | Chief Legal Officer | 21 juin 2018 A | 0 | 0 | 0 | $0 |
| Tara Nickerson | Chief Business Officer | 21 février 2018 A | 2 000 | 0 | 0 | $0 |
| Sarah B. Noonberg | Chief Medical Officer | 16 mai 2017 A | — | 0 | 0 | $0 |
| David B. Mcninch | Chief Commercial Officer | 24 février 2016 A | — | 0 | 0 | $0 |
| Martin Koller | Chief Medical Officer | 24 février 2016 A | 0 | 0 | 0 | $0 |
| John Randall Fawcett | Controller | 29 janvier 2013 A | — | 0 | 0 | $0 |
| William H. Dunn Jr. | Administrateur | 15 mai 2026 A | — | 0 | 0 | $0 |
| Dennis J. Selkoe | Administrateur | 15 mai 2026 A | 2 845 | 0 | 0 | $0 |
| Shane Cooke | Administrateur | 15 mai 2026 A | 0 | 0 | 0 | $0 |
| Lars Ekman | Administrateur | 15 mai 2026 A | 243 | 0 | 0 | $0 |
| Daniel G Welch | Administrateur | 15 mai 2026 A | — | 0 | 0 | $0 |
| COLLIER RICHARD T | Administrateur | 15 mai 2026 A | 1 219 | 0 | 0 | $0 |
| Paula K Cobb | Administrateur | 14 mai 2025 A | — | 0 | 0 | $0 |
| Helen Kim | Administrateur | 14 mai 2025 A | — | 0 | 0 | $0 |
| Karl Anders Olof Harfstrand | Administrateur | 17 mai 2023 A | — | 0 | 0 | $0 |
| Sanjiv Patel | Administrateur | 18 mai 2022 A | — | 0 | 0 | $0 |
| William P Scully | Détenteur de 10% | 18 août 2026 G | 750 000 | 7 | 0 | $3 420 500 |
| EcoR1 Capital, LLC | Détenteur de 10% | 6 mai 2025 S | 5 304 596 | 0 | 0 | $0 |
| Christopher S Henney | — | 12 juillet 2021 M | 0 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 3 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| EcoR1 Capital, LLC, Oleg Nodelman, EcoR1 Capital Fund Qualified, L.P. ×7 dépôts | 29 mai 2025 | 0,00% | Amendement | Investissement passif | SEC |
| Woodford Investment Management LLP, Neil Woodford | 9 octobre 2015 | — | Dépôt initial | Investissement passif | SEC |
| Elan Corporation, plc (2), Elan Science One Limited (2) | 28 décembre 2012 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 26 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0,43% | 10 983 SH | 8 août 2026 | Quotidien |
| IBRN · iShares Trust | 0,41% | 3 678 SH | 8 août 2026 | Quotidien |
| LABU · Direxion Shares ETF Trust | 0,12% | 57 328 NS | 30 avril 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,03% | 2 821 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,03% | 340 612 SH | 8 août 2026 | Quotidien |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,03% | 82 462 NS | 31 mai 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,02% | 28 906 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,02% | 19 314 NS | 30 avril 2026 | N-PORT |
| IWO · iShares Trust | 0,01% | 245 578 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,01% | 177 323 NS | 30 avril 2026 | N-PORT |
| IWM · iShares Trust | 0,01% | 1 140 824 SH | 8 août 2026 | Quotidien |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,01% | 34 579 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,01% | 255 810 SH | 8 août 2026 | Quotidien |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 15 431 SH | 8 août 2026 | Quotidien |
| IWN · iShares Trust | 0,01% | 169 023 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,01% | 129 902 SH | 8 août 2026 | Quotidien |
| DXUV · Dimensional ETF Trust | 0,00% | 1 214 NS | 30 avril 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 5 606 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 1 421 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 18 613 NS | 30 avril 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 53 549 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,00% | 10 944 SH | 8 août 2026 | Quotidien |
| DFUS · Dimensional ETF Trust | 0,00% | 6 950 NS | 30 avril 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 13 125 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 479 945 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3 260 SH | 8 août 2026 | Quotidien |