PVLA — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| MONTANOVA CAPITAL, LLC | $173 512 745 | 1 135 406 | 7,97% | Actions |
| JENNISON ASSOCIATES LLC | $146 801 795 | 960 619 | 6,75% | Actions |
| BlackRock, Inc. | $140 343 317 | 918 357 | 6,45% | Actions |
| Frazier Life Sciences Management, L.P. | $134 848 368 | 882 400 | 6,20% | Actions |
| First Light Asset Management, LLC | $117 961 911 | 771 901 | 5,42% | Actions |
| BVF INC/IL | $102 815 615 | 672 789 | 4,72% | Actions |
| STATE STREET CORP | $99 817 745 | 653 172 | 4,59% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $78 517 999 | 513 794 | 3,61% | Actions |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $73 175 272 | 478 833 | 3,36% | Actions |
| FEDERATED HERMES, INC. | $66 173 352 | 433 015 | 3,04% | Actions |
| VANGUARD GROUP INC | $58 679 676 | 560 616 | 2,70% | Actions |
| Woodline Partners LP | $48 522 948 | 317 517 | 2,23% | Actions |
| ORBIMED ADVISORS LLC | $44 678 455 | 292 360 | 2,05% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $42 213 033 | 276 164 | 1,94% | Actions |
| Siren, L.L.C. | $39 348 858 | 257 485 | 1,81% | Actions |
| PRIMECAP MANAGEMENT CO/CA/ | $39 149 734 | 256 182 | 1,80% | Actions |
| EVENTIDE ASSET MANAGEMENT, LLC | $35 375 385 | 231 484 | 1,63% | Actions |
| EMERALD ADVISERS, LLC | $35 070 051 | 229 486 | 1,61% | Actions |
| FMR LLC | $32 831 927 | 214 841 | 1,51% | Actions |
| ALLIANCEBERNSTEIN L.P. | $31 557 391 | 253 168 | 1,45% | Actions |
| MPM BIOIMPACT LLC | $31 179 406 | 204 027 | 1,43% | Actions |
| GOLDMAN SACHS GROUP INC | $30 795 370 | 201 514 | 1,42% | Actions |
| MORGAN STANLEY | $27 725 827 | 181 428 | 1,27% | Actions |
| First Turn Management, LLC | $23 908 689 | 156 450 | 1,10% | Actions |
| Bellevue Group AG | $23 687 100 | 155 000 | 1,09% | Actions |
| Caption Management, LLC | $21 394 800 | 140 000 | 0,98% | Option de vente |
| EMERALD MUTUAL FUND ADVISERS TRUST | $19 843 219 | 129 847 | 0,91% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $19 707 973 | 128 962 | 0,91% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $18 430 092 | 120 600 | 0,85% | Option d'achat |
| Aberdeen Group plc | $18 374 771 | 120 238 | 0,84% | Actions |
| NORTHERN TRUST CORP | $14 853 034 | 97 193 | 0,68% | Actions |
| NEXTBio Capital Management LP | $13 739 893 | 89 909 | 0,63% | Actions |
| Clio Asset Management LLC | $13 194 937 | 86 343 | 0,61% | Actions |
| NEUBERGER BERMAN GROUP LLC | $12 700 411 | 83 107 | 0,58% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $11 706 012 | 76 600 | 0,54% | Option de vente |
| VANGUARD FIDUCIARY TRUST CO | $11 307 916 | 73 995 | 0,52% | Actions |
| UBS Group AG | $11 083 424 | 72 526 | 0,51% | Actions |
| Avidity Partners Management LP | $10 697 400 | 70 000 | 0,49% | Actions |
| AWM Investment Company, Inc. | $10 608 153 | 69 416 | 0,49% | Actions |
| SEVEN GRAND MANAGERS, LLC | $9 169 200 | 60 000 | 0,42% | Actions |
| Clearbridge Investments, LLC | $9 068 458 | 59 341 | 0,42% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $8 713 159 | 69 901 | 0,40% | Actions |
| BANK OF AMERICA CORP /DE/ | $8 336 942 | 54 554 | 0,38% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $8 140 721 | 53 270 | 0,37% | Actions |
| MILLENNIUM MANAGEMENT LLC | $7 979 038 | 52 212 | 0,37% | Actions |
| Ensign Peak Advisors, Inc | $7 894 681 | 51 660 | 0,36% | Actions |
| HSBC HOLDINGS PLC | $7 641 156 | 50 001 | 0,35% | Actions |
| Nicholas Investment Partners, LP | $7 597 905 | 49 718 | 0,35% | Actions |
| Balyasny Asset Management L.P. | $6 805 992 | 44 536 | 0,31% | Actions |
| Lisanti Capital Growth, LLC | $6 567 440 | 42 975 | 0,30% | Actions |
| WCM INVESTMENT MANAGEMENT, LLC | $6 215 278 | 40 140 | 0,29% | Actions |
| ROYCE & ASSOCIATES LP | $6 190 585 | 40 509 | 0,28% | Actions |
| ORBIMED ADVISORS LLC | $6 112 800 | 40 000 | 0,28% | Option d'achat |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $6 092 169 | 39 865 | 0,28% | Actions |
| Jump Financial, LLC | $6 023 095 | 39 413 | 0,28% | Actions |
| Apis Capital Advisors, LLC | $5 959 980 | 39 000 | 0,27% | Actions |
| Blue Owl Capital Holdings LP | $5 541 100 | 36 259 | 0,25% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $5 439 475 | 35 594 | 0,25% | Actions |
| FIFTH THIRD BANCORP | $5 438 100 | 35 585 | 0,25% | Actions |
| Invesco Ltd. | $5 142 699 | 33 652 | 0,24% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $4 979 334 | 32 583 | 0,23% | Actions |
| FRED ALGER MANAGEMENT, LLC | $4 802 216 | 31 424 | 0,22% | Actions |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $4 786 017 | 31 318 | 0,22% | Actions |
| Bank of New York Mellon Corp | $4 674 306 | 30 587 | 0,21% | Actions |
| CITADEL ADVISORS LLC | $4 645 728 | 30 400 | 0,21% | Option d'achat |
| Caption Management, LLC | $4 584 600 | 30 000 | 0,21% | Option d'achat |
| JANE STREET GROUP, LLC | $4 095 576 | 26 800 | 0,19% | Option d'achat |
| Nuveen, LLC | $3 855 801 | 25 231 | 0,18% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3 820 500 | 25 000 | 0,18% | Actions |
| NOMURA HOLDINGS INC | $3 662 026 | 23 963 | 0,17% | Actions |
| RAYMOND JAMES FINANCIAL INC | $3 616 180 | 23 663 | 0,17% | Actions |
| Legato Capital Management LLC | $3 589 741 | 23 490 | 0,16% | Actions |
| TD Asset Management Inc | $3 476 044 | 22 746 | 0,16% | Actions |
| ACT CAPITAL MANAGEMENT, LLC | $3 438 450 | 22 500 | 0,16% | Actions |
| Russell Investments Group, Ltd. | $3 414 891 | 22 345 | 0,16% | Actions |
| Swiss National Bank | $2 964 708 | 19 400 | 0,14% | Actions |
| Informed Momentum Co LLC | $2 880 504 | 18 849 | 0,13% | Actions |
| F/m Investments LLC | $2 666 098 | 17 446 | 0,12% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 658 610 | 17 397 | 0,12% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2 375 587 | 15 545 | 0,11% | Actions |
| CITIGROUP INC | $2 367 640 | 15 493 | 0,11% | Actions |
| ALPS ADVISORS INC | $2 193 884 | 14 356 | 0,10% | Actions |
| Capricorn Fund Managers Ltd | $2 152 928 | 14 088 | 0,10% | Actions |
| RHUMBLINE ADVISERS | $2 067 339 | 13 528 | 0,09% | Actions |
| Trexquant Investment LP | $2 062 306 | 13 495 | 0,09% | Actions |
| CITADEL ADVISORS LLC | $2 032 506 | 13 300 | 0,09% | Option de vente |
| WELLS FARGO & COMPANY/MN | $1 987 844 | 13 008 | 0,09% | Actions |
| SEI INVESTMENTS CO | $1 957 202 | 12 807 | 0,09% | Actions |
| TWO SIGMA INVESTMENTS, LP | $1 878 769 | 12 294 | 0,09% | Actions |
| OAK RIDGE INVESTMENTS LLC | $1 839 647 | 12 038 | 0,08% | Actions |
| DEUTSCHE BANK AG\ | $1 809 083 | 11 838 | 0,08% | Actions |
| Cresset Asset Management, LLC | $1 777 144 | 11 629 | 0,08% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $1 762 167 | 11 531 | 0,08% | Actions |
| Rafferty Asset Management, LLC | $1 736 188 | 11 361 | 0,08% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 705 777 | 11 162 | 0,08% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $1 593 913 | 10 430 | 0,07% | Actions |
| Mariner, LLC | $1 583 364 | 10 361 | 0,07% | Actions |
| Knights of Columbus Asset Advisors LLC | $1 532 937 | 10 031 | 0,07% | Actions |
| XTX Topco Ltd | $1 354 138 | 8 861 | 0,06% | Actions |
| JPMORGAN CHASE & CO | $1 303 753 | 8 420 | 0,06% | Actions |
| MARTINGALE ASSET MANAGEMENT L P | $1 284 605 | 8 406 | 0,06% | Actions |
| Legal & General Group Plc | $1 221 642 | 7 994 | 0,06% | Actions |
| TUDOR INVESTMENT CORP ET AL | $1 208 195 | 7 906 | 0,06% | Actions |
| MetLife Investment Management, LLC | $978 812 | 6 405 | 0,04% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $977 895 | 6 399 | 0,04% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $976 825 | 6 392 | 0,04% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $976 436 | 6 372 | 0,04% | Actions |
| Vanguard Global Advisers, LLC | $948 859 | 6 209 | 0,04% | Actions |
| ASPIRIANT, LLC | $894 303 | 5 852 | 0,04% | Actions |
| PROFUND ADVISORS LLC | $879 173 | 5 753 | 0,04% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $873 519 | 5 716 | 0,04% | Actions |
| Penn Capital Management Company, LLC | $841 427 | 5 506 | 0,04% | Actions |
| ExodusPoint Capital Management, LP | $839 593 | 5 494 | 0,04% | Actions |
| Squarepoint Ops LLC | $790 996 | 5 176 | 0,04% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $787 176 | 5 151 | 0,04% | Actions |
| FRANKLIN RESOURCES INC | $739 343 | 4 838 | 0,03% | Actions |
| CAPTRUST FINANCIAL ADVISORS | $722 991 | 4 731 | 0,03% | Actions |
| LPL Financial LLC | $706 792 | 4 625 | 0,03% | Actions |
| BROWN ADVISORY INC | $664 614 | 4 349 | 0,03% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $658 195 | 4 307 | 0,03% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $641 538 | 4 198 | 0,03% | Actions |
| Creative Planning | $630 688 | 4 127 | 0,03% | Actions |
| CITADEL ADVISORS LLC | $537 926 | 3 520 | 0,02% | Actions |
| LETKO, BROSSEAU & ASSOCIATES INC | $534 870 | 3 500 | 0,02% | Actions |
| State of New Jersey Common Pension Fund D | $495 137 | 3 240 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $494 526 | 3 236 | 0,02% | Actions |
| Virtus Investment Advisers, LLC | $459 530 | 3 007 | 0,02% | Actions |
| CERTUITY, LLC | $458 460 | 3 000 | 0,02% | Actions |
| KEYBANK NATIONAL ASSOCIATION/OH | $455 862 | 2 983 | 0,02% | Actions |
| JANUS HENDERSON GROUP PLC | $449 946 | 3 600 | 0,02% | Actions |
| MARSHALL WACE, LLP | $435 842 | 2 852 | 0,02% | Actions |
| BARCLAYS PLC | $426 827 | 2 793 | 0,02% | Actions |
| ARIZONA STATE RETIREMENT SYSTEM | $422 547 | 2 765 | 0,02% | Actions |
| KLP KAPITALFORVALTNING AS | $397 332 | 2 600 | 0,02% | Actions |
| Vanguard Investments Australia, Ltd. | $395 193 | 2 586 | 0,02% | Actions |
| Calamos Advisors LLC | $392 900 | 2 571 | 0,02% | Actions |
| DELTEC ASSET MANAGEMENT LLC | $366 768 | 2 400 | 0,02% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $353 932 | 2 316 | 0,02% | Actions |
| DNB Asset Management AS | $342 928 | 2 244 | 0,02% | Actions |
| Alyeska Investment Group, L.P. | $339 719 | 2 223 | 0,02% | Actions |
| SIMPLEX TRADING, LLC | $338 954 | 2 218 | 0,02% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $335 746 | 2 197 | 0,02% | Actions |
| Brevan Howard Capital Management LP | $333 148 | 2 180 | 0,02% | Actions |
| JANE STREET GROUP, LLC | $320 922 | 2 100 | 0,01% | Option de vente |
| ENVESTNET ASSET MANAGEMENT INC | $308 238 | 2 017 | 0,01% | Actions |
| AlphaQuest LLC | $288 261 | 2 754 | 0,01% | Actions |
| PRUDENTIAL FINANCIAL INC | $268 199 | 1 755 | 0,01% | Actions |
| E Fund Management Co., Ltd. | $244 818 | 1 602 | 0,01% | Actions |
| TWO SIGMA ADVISERS, LP | $240 741 | 2 300 | 0,01% | Actions |
| Quantinno Capital Management LP | $231 828 | 1 517 | 0,01% | Actions |
| ProShare Advisors LLC | $219 143 | 1 434 | 0,01% | Actions |
| China Universal Asset Management Co., Ltd. | $207 377 | 1 357 | 0,01% | Actions |
| Pictet Asset Management Holding SA | $203 403 | 1 331 | 0,01% | Actions |
| Fulcrum Asset Management LLP | $174 350 | 1 126 | 0,01% | Actions |
| Chung Wu Investment Group, LLC | $168 102 | 1 100 | 0,01% | Actions |
| Spire Wealth Management | $152 820 | 1 000 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $152 209 | 996 | 0,01% | Actions |
| State of Wyoming | $134 329 | 879 | 0,01% | Actions |
| ROYAL BANK OF CANADA | $105 000 | 685 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $97 632 | 638 868 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $83 286 | 545 | 0,00% | Actions |
| Quantbot Technologies LP | $70 603 | 462 | 0,00% | Actions |
| Archer Investment Corp | $68 616 | 449 | 0,00% | Actions |
| Kemnay Advisory Services Inc. | $57 155 | 374 | 0,00% | Actions |
| HighMark Wealth Management LLC | $49 181 | 322 | 0,00% | Actions |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $34 996 | 229 | 0,00% | Actions |
| JONES FINANCIAL COMPANIES LLLP | $33 495 | 226 | 0,00% | Actions |
| Bayforest Capital Ltd | $31 787 | 208 | 0,00% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $25 674 | 168 | 0,00% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $16 046 | 105 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $13 906 | 91 | 0,00% | Actions |
| Larson Financial Group LLC | $11 156 | 73 | 0,00% | Actions |
| EASTERN BANK | $7 947 | 52 | 0,00% | Actions |
| PRIVATE TRUST CO NA | $7 641 | 50 | 0,00% | Actions |
| COMERICA BANK | $5 966 | 57 | 0,00% | Actions |
| Sterling Capital Management LLC | $5 960 | 39 | 0,00% | Actions |
| GAMMA Investing LLC | $5 654 | 37 | 0,00% | Actions |
| Global Retirement Partners, LLC | $4 737 | 31 | 0,00% | Actions |
| PNC Financial Services Group, Inc. | $4 737 | 31 | 0,00% | Actions |
| CWM, LLC | $4 363 | 35 | 0,00% | Actions |
| Rossby Financial, LCC | $3 668 | 24 | 0,00% | Actions |
| Quarry LP | $3 515 | 23 | 0,00% | Actions |
| SIGNATUREFD, LLC | $3 209 | 21 | 0,00% | Actions |
| Steward Partners Investment Advisory, LLC | $3 056 | 20 | 0,00% | Actions |
| Arax Advisory Partners | $2 903 | 19 | 0,00% | Actions |
| Stone House Investment Management, LLC | $2 751 | 18 | 0,00% | Actions |
| US BANCORP \DE\ | $2 598 | 17 | 0,00% | Actions |
| Allworth Financial LP | $2 140 | 14 | 0,00% | Actions |
| Truvestments Capital LLC | $2 139 | 14 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $1 987 | 13 | 0,00% | Actions |
| CoreCap Advisors, LLC | $1 681 | 11 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $1 528 | 10 | 0,00% | Actions |
| Keating Financial Advisory Services, Inc. | $1 223 | 8 | 0,00% | Actions |
| WPG Advisers, LLC | $1 223 | 8 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $1 070 | 7 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $917 | 6 | 0,00% | Actions |
| PEAPACK GLADSTONE FINANCIAL CORP | $898 | 5 875 | 0,00% | Actions |
| Mitsubishi UFJ Asset Management (UK) Ltd. | $841 | 5 500 | 0,00% | Actions |
| FINANCIAL CONSULATE, INC | $765 | 5 | 0,00% | Actions |
| Fortitude Family Office, LLC | $764 | 5 | 0,00% | Actions |
| Point72 Europe (London) LLP | $728 | 12 | 0,00% | Actions |
| SG Americas Securities, LLC | $473 | 3 098 | 0,00% | Actions |
| Hughes Financial Services, LLC | $458 | 3 | 0,00% | Actions |
| Smartleaf Asset Management LLC | $155 | 1 | 0,00% | Actions |
| TFC Financial Management, Inc. | $153 | 1 | 0,00% | Actions |
| Essential Partners LLC | $153 | 1 | 0,00% | Actions |
| NFSG Corp | $115 | 1 | 0,00% | Actions |
| KBC Group NV | $34 | 224 | 0,00% | Actions |
| Pacer Advisors, Inc. | $29 | 190 | 0,00% | Actions |
| Covestor Ltd | $1 | 4 | 0,00% | Actions |