SPRB Spruce Biosciences, Inc. - Common Stock
$53,10
Prix · Aoû 19, 2026
Données fondamentales au Aoû 12, 2026
Fourchette 52 semaines
$7–$240
20% of range
Note des analystes
BUY
14 analysts
Objectif de cours
$148
+178% upside
P/E (TTM)
-1.0
ROE
-139.9%
Marge nette
—
SPRB Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$53.10
Capitalisation Boursière
$73M
P/E (TTM)
-1.0
BPA (TTM)
$-50.83
Revenus (TTM)
$0
Rendement div.
—
ROE
-139.9%
Dette/Capitaux propres
0.0
Fourchette 52 semaines
$7 – $240
SPRB Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
$0
2022-12-31
→
2025-12-31
BPA
$-50.83
2021-12-31
→
2025-12-31
Flux de trésorerie libre
—
2020-12-31
→
2024-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
SPRB
Médiane des pairs
P/E (TTM)
-1.0
—
P/B
1.7
1.2
EV / EBITDA
-0.7
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
SPRB
Médiane des pairs
ROA
-79.3%
-85.8%
ROE
-139.9%
-122.3%
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
SPRB
Médiane des pairs
Debt / Equity (Dette / Capitaux propres)
0.0
—
Current Ratio (Ratio de liquidité)
5.2
4.5
Quick Ratio (Ratio de liquidité réduite)
4.8
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
SPRB
Médiane des pairs
Revenue YoY (Chiffre d'affaires YoY)
-51.3%
—
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
SPRB
Médiane des pairs
SPRB Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
14 analystes
- Achat fort 5 35,7%
- Achat 8 57,1%
- Conserver 1 7,1%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
8 analystes · 2026-08-17
Médiane
$142.00
← En dessous de tous les objectifs
$53.10
Bas
$104.00
Haut
$230.00
Objectif médian
$142.00
+167,4%
Objectif moyen
$147.88
+178,5%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
-3.2%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-6.68 | $-5.92 | -0.76% |
| 31 mars 2026 | $-8.94 | $-8.99 | 0.05% |
| 31 décembre 2025 | $-11.28 | $-8.15 | -3.1% |
| 30 septembre 2025 | $-14.58 | $-14.21 | -0.37% |
| 30 juin 2025 | $-3.50 | $-19.51 | 16.0% |
| 31 mars 2025 | $-24.00 | $-16.42 | -7.6% |
| 31 décembre 2024 | $-42.75 | $-16.07 | -26.7% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| SPRB | $120M | -1.7 | -51.3% | — | -139.9% | — |
| OKUR | — | -0.7 | — | -1733.7% | -88.6% | — |
| CNTN | $112M | -2.7 | — | — | -18.0% | — |
| TNYA | $154M | -1.2 | — | — | -81.2% | — |
| UNCY | $128M | -3.5 | -29.0% | — | -113.9% | — |
| CNTB | $159M | -2.8 | -99.8% | -86687.5% | -97.9% | — |
| EQ | $95M | -4.0 | 13.9% | — | -133.1% | — |
| IMDX | $215M | -4.5 | 115.6% | -1238.5% | 330.8% | 56.7% |
| HURA | — | -1.2 | — | — | — | — |
| INO | $120M | -1.0 | -70.0% | -130000.0% | -322.8% | — |
| OTLK | $57M | -0.6 | — | -4416.2% | 193.1% | 4.0% |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $0 | $5M | $10M | $0 | |
| R&D Expense | $20M | $46M | $49M | $35M | |
| SG&A Expense | $17M | $15M | $13M | $12M | |
| Operating Expenses | $37M | $61M | $62M | $47M | |
| Operating Income | $-37M | $-56M | $-52M | $-47M | |
| Interest Expense | $90.0K | $307.0K | $483.0K | $420.0K | |
| Income Tax | $0 | $0 | $0 | $0 | |
| Net Income | $-39M | $-53M | $-48M | $-46M | |
| EPS (Basic) | $-50.83 | $-96.40 | $-1.24 | $-1.96 | |
| EPS (Diluted) | $-50.83 | $-96.40 | $-1.24 | $-1.96 | |
| Shares (Basic) | 766,598 | 550,146 | 38,510,220 | 23,527,116 | |
| Shares (Diluted) | 766,598 | 550,146 | 38,510,220 | 23,527,116 | |
| EBITDA | $-37M | $-56M | $-52M | $-47M |
Bilan 22
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $49M | $39M | $96M | $24M | |
| Short-term Investments | · | · | $0 | $55M | |
| Receivables | · | · | · | $0 | |
| Prepaid Expense | $353.0K | $3M | $4M | $3M | |
| Other Current Assets | $3M | $2M | $2M | $1M | |
| Current Assets | $52M | $44M | $102M | $84M | |
| Other Non-current Assets | $243.0K | $69.0K | $582.0K | $640.0K | |
| Total Assets | $53M | $45M | $104M | $86M | |
| Accounts Payable | $943.0K | $1M | $3M | $1M | |
| Accrued Liabilities | $9M | $12M | $15M | · | |
| Current Liabilities | $10M | $15M | $24M | $12M | |
| Capital Leases | $419.0K | $736.0K | $1M | $1M | |
| Other Non-current Liabilities | $0 | $282.0K | $236.0K | $161.0K | |
| Total Liabilities | $11M | $16M | $27M | $17M | |
| Long-term Debt | $0 | $2M | $4M | $6M | |
| Total Debt | $0 | $2M | $3M | $5M | |
| Common Stock | $0 | $0 | $4.0K | $3.0K | |
| Retained Earnings | $-289M | $-250M | $-197M | $-149M | |
| AOCI | · | · | $0 | $-558.0K | |
| Stockholders' Equity | $43M | $29M | $77M | $68M | |
| Liabilities + Equity | $53M | $45M | $104M | $86M | |
| Shares Outstanding | 1,372,043 | 563,042 | 547,019 | 23,601,004 |
Flux de trésorerie 9
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| D&A | $21.0K | $46.0K | $70.0K | $74.0K | |
| Stock-based Comp | $3M | $5M | $5M | $4M | |
| Operating Cash Flow | $-33M | $-56M | $-33M | $-42M | |
| CapEx | · | $0 | $7.0K | $8.0K | |
| Investing Cash Flow | · | $0 | $56M | $24M | |
| Debt Issued | · | · | · | $0 | |
| Net Debt Issued | $-2M | $-2M | $-2M | $0 | |
| Financing Cash Flow | $43M | $-2M | $49M | $-241.0K | |
| Free Cash Flow | · | $-56M | $-33M | $-42M |
Rentabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | · | -1143.4% | -515.3% | · | |
| Net Margin | · | -1079.9% | -475.0% | · | |
| EBITDA Margin | · | -1143.4% | -515.3% | · | |
| ROA | -79.3% | -71.1% | -50.5% | -43.5% | |
| ROE | -139.9% | -131.8% | -59.2% | -62.8% |
Liquidité et Solvabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 5.2 | 2.9 | 4.2 | 6.7 | |
| Quick Ratio | 4.8 | 2.5 | 3.9 | 6.4 | |
| Debt / Equity | 0.0 | 0.1 | 0.0 | 0.1 | |
| LT Debt / Equity | 0.0 | 0.0 | 0.0 | 0.0 | |
| Interest Coverage | -405.7 | -182.9 | -107.6 | -112.6 |
Efficacité 1
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | 0.1 | · |
Taux de croissance 1
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | · | -51.3% | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $0 | $5M | $10M | $0 | |
| Net Income TTM | $-39M | $-53M | $-48M | $-46M | |
| Market Cap | $120M | $99.77B | $676.22B | $145.63B | |
| Enterprise Value | $71M | $99.73B | $676.13B | $145.56B | |
| P/E | -1.7 | -24.5 | -13291.3 | -3148.3 | |
| P/S | · | 20315.9 | 67025.8 | · | |
| P/B | 2.8 | 3461.8 | 8838.5 | 2126.5 | |
| P / Tangible Book | 2.8 | 3461.8 | 8838.5 | 2126.5 | |
| P / Cash Flow | -3.6 | -1782.8 | -20322.3 | -3493.8 | |
| P / FCF | · | -1782.8 | -20318.0 | -3493.2 | |
| EV / EBITDA | -1.9 | -1776.2 | -13004.2 | -3078.5 | |
| EV / FCF | · | -1782.1 | -20315.2 | -3491.4 | |
| EV / Revenue | · | 20308.4 | 67016.5 | · | |
| Earnings Yield | -58.4% | -4.1% | -0.01% | -0.03% |
Compte de résultat 13
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | $0 | $697.0K | $602.0K | $2M | $2M | $3M | $3M | $2M | $2M | $0 | $0 | |
| R&D Expense | $12M | $8M | $4M | $5M | $-430.0K | $11M | $21M | $7M | $8M | $10M | $11M | $13M | $13M | $12M | $9M | $9M | |
| SG&A Expense | $4M | $4M | $7M | $3M | $3M | $4M | $3M | $3M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | $3M | |
| Operating Expenses | $17M | $12M | $11M | $8M | $3M | $14M | $25M | $10M | $12M | $15M | $14M | $17M | $16M | $15M | $12M | $12M | |
| Operating Income | $-17M | $-12M | $-11M | $-8M | $-3M | $-14M | $-24M | $-9M | $-10M | $-13M | $-11M | $-14M | $-14M | $-13M | $-12M | $-12M | |
| Interest Expense | $1M | $674.0K | $6.0K | $19.0K | $29.0K | $36.0K | $56.0K | $71.0K | $83.0K | $97.0K | $106.0K | $119.0K | $127.0K | $131.0K | $129.0K | $110.0K | |
| Other Non-op | · | · | · | · | · | · | · | $808.0K | $938.0K | $1M | · | $1M | $1M | $539.0K | · | · | |
| Net Income | $-16M | $-12M | $-15M | $-8M | $-2M | $-14M | $-24M | $-9M | $-9M | $-12M | $-10M | $-12M | $-13M | $-13M | $-11M | $-11M | |
| EPS (Basic) | $-6.68 | $-8.94 | $-32.43 | $-14.58 | $-3.50 | $-23.95 | $-63.64 | $-15.75 | $-16.73 | $-0.28 | $-0.22 | $-0.30 | $-0.32 | $-0.40 | $-0.47 | $-0.48 | |
| EPS (Diluted) | $-6.68 | $-8.94 | $-32.43 | $-14.58 | $-3.50 | $-23.95 | $-63.64 | $-15.75 | $-16.73 | $-0.28 | $-0.22 | $-0.30 | $-0.32 | $-0.40 | $-0.47 | $-0.48 | |
| Shares (Basic) | 2,431,075 | 1,372,084 | -44,332,551 | 563,066 | 591,137 | 586,142 | -41,645,519 | 550,645 | 548,789 | 41,096,231 | -74,648,557 | 40,710,692 | 40,547,925 | 31,900,160 | -47,019,042 | 23,560,250 | |
| Shares (Diluted) | 2,431,075 | 1,372,084 | -44,332,551 | 563,066 | 591,137 | 586,142 | -41,645,519 | 550,645 | 548,789 | 41,096,231 | -74,648,557 | 40,710,692 | 40,547,925 | 31,900,160 | -47,019,042 | 23,560,250 | |
| EBITDA | $-17M | $-12M | · | $-8M | $-3M | $-14M | · | $-9M | $-10M | $-13M | · | $-14M | $-14M | $-13M | · | $-12M |
Bilan 22
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $96M | $54M | $49M | $11M | $16M | $26M | $39M | $60M | $70M | $81M | $96M | $99M | $97M | $74M | $24M | $22M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | $9M | $23M | $45M | $55M | $69M | |
| Receivables | · | · | · | · | · | · | · | · | · | · | · | · | · | $15M | · | · | |
| Prepaid Expense | $5M | $864.0K | $353.0K | $932.0K | $2M | $3M | $3M | $3M | $3M | $3M | $4M | $3M | $3M | $3M | $3M | $3M | |
| Other Current Assets | $234.0K | $88.0K | $3M | $3M | $3M | $2M | $2M | $860.0K | $2M | $2M | $2M | $419.0K | $206.0K | $253.0K | $1M | · | |
| Current Assets | $101M | $55M | $52M | $15M | $21M | $31M | $44M | $64M | $74M | $86M | $102M | $111M | $124M | $137M | $84M | $93M | |
| Other Non-current Assets | $1M | $539.0K | $243.0K | $62.0K | $64.0K | $204.0K | $69.0K | $531.0K | $547.0K | $553.0K | $582.0K | $607.0K | $536.0K | $525.0K | $640.0K | $667.0K | |
| Total Assets | $103M | $56M | $53M | $15M | $22M | $32M | $45M | $65M | $76M | $88M | $104M | $113M | $126M | $139M | $86M | $95M | |
| Accounts Payable | $1M | $3M | $943.0K | $1M | $807.0K | $2M | $1M | $2M | $682.0K | $2M | $3M | $3M | $945.0K | $3M | $1M | $2M | |
| Accrued Liabilities | $7M | $8M | $9M | $8M | $6M | $12M | $12M | $8M | $11M | · | $15M | · | · | · | · | · | |
| Current Liabilities | $11M | $12M | $10M | $9M | $8M | $16M | $15M | $12M | $14M | $18M | $24M | $24M | $23M | $23M | $12M | $12M | |
| Capital Leases | $245.0K | $332.0K | $419.0K | $500.0K | $580.0K | $659.0K | $736.0K | · | · | $950.0K | $1M | · | · | · | $1M | $998.0K | |
| Other Non-current Liabilities | · | · | $0 | $0 | $0 | $0 | $282.0K | $273.0K | $262.0K | $250.0K | $236.0K | $220.0K | $202.0K | $181.0K | $161.0K | $139.0K | |
| Total Liabilities | $19M | $22M | $11M | $10M | $9M | $16M | $16M | $13M | $16M | $21M | $27M | $28M | $29M | $31M | $17M | $17M | |
| Long-term Debt | $20M | $20M | $0 | $549.0K | $972.0K | $1M | $2M | $2M | $3M | $3M | $3M | $4M | $5M | $5M | $5M | $6M | |
| Total Debt | $7M | $6M | · | $539.0K | $943.0K | $1M | · | $2M | $3M | $3M | · | $4M | $4M | $5M | · | $5M | |
| Common Stock | $0 | $0 | $0 | $0 | $0 | $4.0K | $0 | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | |
| Retained Earnings | $-318M | $-302M | $-289M | $-275M | $-266M | $-264M | $-250M | $-227M | $-218M | $-209M | $-197M | $-187M | $-175M | $-162M | $-149M | $-138M | |
| AOCI | · | · | · | · | · | · | · | · | · | · | · | $-3.0K | $-55.0K | $-188.0K | $-558.0K | $-873.0K | |
| Stockholders' Equity | $84M | $35M | $43M | $5M | $13M | $15M | $29M | $52M | $59M | $67M | $77M | $85M | $97M | $108M | $68M | $78M | |
| Liabilities + Equity | $103M | $56M | $53M | $15M | $22M | $32M | $45M | $65M | $76M | $88M | $104M | $113M | $126M | $139M | $86M | $95M | |
| Shares Outstanding | 2,752,810 | 1,372,278 | 1,372,043 | 563,491 | 563,042 | 42,231,285 | 563,042 | 41,302,599 | 41,302,599 | 41,154,799 | 41,029,832 | 40,710,692 | 40,710,692 | 39,746,116 | 23,601,004 | 23,560,250 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $631.0K | $252.0K | $5.0K | $3.0K | $7.0K | $6.0K | $9.0K | $10.0K | $12.0K | $15.0K | $16.0K | $17.0K | $18.0K | $19.0K | $24.0K | $23.0K | |
| Stock-based Comp | $871.0K | $689.0K | $2M | $415.0K | $-77.0K | $544.0K | $961.0K | $1M | $2M | $2M | $1M | $1M | $1M | $1M | $802.0K | $783.0K | |
| Operating Cash Flow | $-22M | $-9M | $-6M | $-5M | $-9M | $-13M | $-21M | $-9M | $-11M | $-15M | $-11M | $-12M | $2M | $-12M | $-12M | $-9M | |
| CapEx | $135.0K | $10.0K | · | · | $0 | $0 | · | · | · | · | $0 | $7.0K | · | · | $0 | $2.0K | |
| Investing Cash Flow | $-135.0K | $-10.0K | · | · | $0 | $0 | · | $0 | $0 | $0 | $9M | $14M | $22M | $10M | $15M | $-17M | |
| Debt Issued | $0 | $14M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Debt Issued | · | $14M | · | · | · | $-405.0K | · | · | · | $-405.0K | · | · | · | $-405.0K | · | · | |
| Financing Cash Flow | $64M | $14M | $45M | $-402.0K | $-400.0K | $-411.0K | $-625.0K | $-405.0K | $-365.0K | $-227.0K | $-552.0K | $-405.0K | $-432.0K | $51M | $36.0K | $-90.0K | |
| Free Cash Flow | · | $-9M | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Rentabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | -1562.8% | -623.4% | -631.0% | · | -444.4% | -645.4% | -672.1% | · | · | |
| Net Margin | · | · | · | · | · | · | · | -1440.4% | -570.2% | -580.7% | · | -402.0% | -592.3% | -651.3% | · | · | |
| EBITDA Margin | · | · | · | · | · | · | · | -1562.8% | -623.4% | -631.0% | · | -444.4% | -645.4% | -672.1% | · | · | |
| ROA | -26.0% | -27.9% | · | -20.4% | -4.2% | -23.6% | · | -9.7% | -9.1% | -10.3% | · | -11.9% | -11.1% | -10.1% | · | -9.9% | |
| ROE | -33.5% | -49.1% | · | -28.8% | -5.7% | -34.3% | · | -12.7% | -11.8% | -13.3% | · | -15.1% | -13.8% | -12.3% | · | -11.5% |
Liquidité et Solvabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.2 | 4.7 | · | 1.5 | 2.6 | 2.0 | · | 5.4 | 5.2 | 4.7 | · | 4.6 | 5.5 | 6.0 | · | 7.8 | |
| Quick Ratio | 8.8 | 4.6 | · | 1.1 | 2.0 | 1.6 | · | 5.1 | 4.9 | 4.4 | · | 4.5 | 5.3 | 5.8 | · | 7.5 | |
| Debt / Equity | 0.1 | 0.2 | · | 0.1 | 0.1 | 0.1 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.1 | |
| LT Debt / Equity | 0.1 | 0.2 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Interest Coverage | -15.1 | -17.8 | · | -433.1 | -92.8 | -402.6 | · | -132.5 | -120.9 | -130.2 | · | -114.8 | -110.0 | -100.8 | · | -105.1 |
Efficacité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | |
| Receivables Turnover | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.3 | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $602.0K | $602.0K | · | $602.0K | $2M | $4M | · | $7M | $9M | $9M | · | $7M | $4M | $2M | · | · | |
| Net Income TTM | $-39M | $-37M | · | $-33M | $-34M | $-44M | · | $-42M | $-46M | $-50M | · | $-49M | $-49M | $-48M | · | $-46M | |
| Market Cap | $149M | $90M | · | $5M | $231M | $68.89B | · | $110.36B | $120.35B | $181.96B | · | $517.53B | $492.34B | $494.09B | · | $181.56B | |
| Enterprise Value | $59M | $42M | · | $-5M | $216M | $68.87B | · | $110.30B | $120.28B | $181.88B | · | $517.43B | $492.23B | $493.98B | · | $181.48B | |
| P/E | -1.6 | -1.3 | · | -0.3 | -11.3 | -49.3 | · | -80.8 | -165.3 | -3401.0 | · | -8475.0 | -7072.4 | -6577.4 | · | -3892.0 | |
| P/S | 246.9 | 149.0 | · | 8.4 | 104.5 | 16347.8 | · | 15144.1 | 13598.4 | 19769.2 | · | 71859.9 | 119240.7 | 251575.3 | · | · | |
| P/B | 1.8 | 2.6 | · | 0.9 | 17.5 | 4495.5 | · | 2137.1 | 2033.9 | 2731.1 | · | 6061.5 | 5098.8 | 4575.1 | · | 2313.6 | |
| P / Tangible Book | 1.8 | 2.6 | · | 0.9 | 17.5 | 4495.5 | · | 2137.1 | 2033.9 | 2731.1 | · | 6061.5 | 5098.8 | 4575.1 | · | 2313.6 | |
| P / Cash Flow | · | -10.3 | · | · | · | -5412.9 | · | · | · | -12164.4 | · | · | · | -41907.9 | · | · | |
| P / FCF | · | -10.3 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EV / EBITDA | -3.6 | -3.5 | · | 0.6 | -80.1 | -4752.0 | · | -11723.8 | -11984.7 | -14397.0 | · | -37884.8 | -35229.6 | -37425.6 | · | -15702.7 | |
| EV / FCF | · | -4.8 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EV / Revenue | 98.8 | 69.9 | · | -8.4 | 97.5 | 16342.1 | · | 15136.2 | 13590.8 | 19760.7 | · | 71845.4 | 119212.5 | 251517.2 | · | · | |
| Earnings Yield | -62.4% | -78.0% | · | -381.6% | -8.8% | -2.0% | · | -1.2% | -0.61% | -0.03% | · | -0.01% | -0.01% | -0.02% | · | -0.03% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $0 | $5M | $10M | $0 | — |
| Marge d'exploitation % | — | -1143.4% | -515.3% | — | — |
| Résultat net | $-39M | $-53M | $-48M | $-46M | $-42M |
| BPA dilué | $-50.83 | $-96.40 | $-1.24 | $-1.96 | $-1.81 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Dette / Capitaux propres | 0.0 | 0.1 | 0.0 | 0.1 | 0.0 |
| Ratio de liquidité | 5.2 | 2.9 | 4.2 | 6.7 | 10.4 |
| Ratio de liquidité réduite | 4.8 | 2.5 | 3.9 | 6.4 | 10.0 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | — | $-56M | $-33M | $-42M | $-36M |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 64 déclarants · $85.1M total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 36 (+24 vs T. préc.) | 4 (-5 vs T. préc.) | 14 (+8 vs T. préc.) | 5 (0 vs T. préc.) | +868K |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $10 800 000 | 200 000 | 12,69% | Actions |
| MILLENNIUM MANAGEMENT LLC | $8 692 974 | 160 981 | 10,22% | Actions |
| Ikarian Capital, LLC | $6 553 224 | 121 356 | 7,70% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $6 443 874 | 119 331 | 7,57% | Actions |
| Alyeska Investment Group, L.P. | $4 410 234 | 81 671 | 5,18% | Actions |
| ADAR1 Capital Management, LLC | $3 656 718 | 67 717 | 4,30% | Actions |
| AIGH Capital Management LLC | $3 302 532 | 61 158 | 3,88% | Actions |
| Cable Car Capital, LP | $3 240 000 | 60 000 | 3,81% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $3 228 503 | 59 780 | 3,79% | Actions |
| STATE STREET CORP | $2 724 300 | 50 450 | 3,20% | Actions |
| CITADEL ADVISORS LLC | $2 535 840 | 46 960 | 2,98% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $2 272 320 | 42 080 | 2,67% | Actions |
| STEMPOINT CAPITAL LP | $2 234 952 | 41 388 | 2,63% | Actions |
| Eversept Partners, LP | $2 160 000 | 40 000 | 2,54% | Actions |
| Carlyle Group Inc. | $2 085 493 | 38 620 | 2,45% | Actions |
| Affinity Asset Advisors, LLC | $1 620 000 | 30 000 | 1,90% | Actions |
| DIADEMA PARTNERS LP | $1 620 000 | 30 000 | 1,90% | Actions |
| Stonepine Capital Management, LLC | $1 554 930 | 28 795 | 1,83% | Actions |
| Point72 Asset Management, L.P. | $1 527 012 | 28 278 | 1,79% | Actions |
| GOLDMAN SACHS GROUP INC | $1 480 086 | 27 409 | 1,74% | Actions |
| Quinn Opportunity Partners LLC | $1 447 740 | 26 810 | 1,70% | Actions |
| UBS Group AG | $1 262 574 | 23 381 | 1,48% | Actions |
| ExodusPoint Capital Management, LP | $1 188 000 | 22 000 | 1,40% | Actions |
| Knott David M Jr | $1 080 000 | 20 000 | 1,27% | Actions |
| Rosalind Advisors, Inc. | $1 080 000 | 20 000 | 1,27% | Actions |
| AMERIPRISE FINANCIAL INC | $1 017 036 | 18 834 | 1,20% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $998 784 | 18 496 | 1,17% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $991 494 | 18 361 | 1,17% | Actions |
| Balyasny Asset Management L.P. | $655 452 | 12 138 | 0,77% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $429 732 | 7 958 | 0,51% | Actions |
| Persistent Asset Partners Ltd | $414 558 | 7 677 | 0,49% | Actions |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $387 828 | 7 182 | 0,46% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $318 384 | 5 896 | 0,37% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $253 800 | 4 700 | 0,30% | Actions |
| Pale Fire Capital SE | $206 172 | 3 818 | 0,24% | Actions |
| RHUMBLINE ADVISERS | $190 026 | 3 519 | 0,22% | Actions |
| DEUTSCHE BANK AG\ | $143 208 | 2 652 | 0,17% | Actions |
| WELLS FARGO & COMPANY/MN | $125 766 | 2 329 | 0,15% | Actions |
| Bank of New York Mellon Corp | $120 798 | 2 237 | 0,14% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $102 600 | 1 900 | 0,12% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $67 608 | 1 252 | 0,08% | Actions |
| JPMORGAN CHASE & CO | $62 977 | 1 127 | 0,07% | Actions |
| CITIGROUP INC | $59 832 | 1 108 | 0,07% | Actions |
| Lion Point Capital, LP | $54 000 | 1 000 | 0,06% | Actions |
| Police & Firemen's Retirement System of New Jersey | $46 656 | 864 | 0,05% | Actions |
| VANGUARD GROUP INC | $39 374 | 452 | 0,05% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $24 462 | 453 | 0,03% | Actions |
| Vanguard Global Advisers, LLC | $24 408 | 452 | 0,03% | Actions |
| NORTHERN TRUST CORP | $22 950 | 425 | 0,03% | Actions |
| BARCLAYS PLC | $20 574 | 381 | 0,02% | Actions |
| FMR LLC | $18 522 | 343 | 0,02% | Actions |
| BlackRock, Inc. | $18 360 | 340 | 0,02% | Actions |
| Legal & General Group Plc | $14 219 | 264 | 0,02% | Actions |
| Ameritas Investment Partners, Inc. | $13 338 | 247 | 0,02% | Actions |
| Tower Research Capital LLC (TRC) | $13 284 | 246 | 0,02% | Actions |
| Russell Investments Group, Ltd. | $11 718 | 217 | 0,01% | Actions |
| SBI Securities Co., Ltd. | $10 854 | 201 | 0,01% | Actions |
| ROYAL BANK OF CANADA | $6 000 | 120 | 0,01% | Actions |
| Sterling Capital Management LLC | $2 322 | 43 | 0,00% | Actions |
| JONES FINANCIAL COMPANIES LLLP | $1 653 | 30 | 0,00% | Actions |
| CALDWELL SUTTER CAPITAL, INC. | $702 | 13 | 0,00% | Actions |
| Friedenthal Financial | $378 | 7 | 0,00% | Actions |
| MORGAN STANLEY | $108 | 2 | 0,00% | Actions |
| Cassaday & Co Wealth Management LLC | $108 | 2 | 0,00% | Actions |
Initiés de la société 19 initiés · 6 dirigeants · 10 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Javier B. Szwarcberg | CHIEF EXECUTIVE OFFICER | 30 juin 2026 A | 19 270 | 0 | 0 | $0 |
| Richard King | Chief Executive Officer | 30 juin 2021 J | 2 230 | 0 | 0 | $0 |
| Samir M. Gharib | President & CFO | 29 décembre 2023 A | 202 776 | 0 | 0 | $0 |
| Adrian W Quartel | Chief Medical Officer | 27 juillet 2026 A | — | 0 | 0 | $0 |
| Ralph William Charlton III | Chief Medical Officer | 29 décembre 2023 A | 55 373 | 0 | 0 | $0 |
| Subaweerage Dias | Chief Medical Officer | 16 décembre 2021 A | — | 0 | 0 | $0 |
| Percival Barretto-Ko | Administrateur | 25 mai 2023 A | — | 0 | 0 | $0 |
| Kirk Ways | Administrateur | 25 mai 2023 A | — | 0 | 0 | $0 |
| Camilla V Simpson | Administrateur | 25 mai 2023 A | 0 | 0 | 0 | $0 |
| Bali Muralidhar | Administrateur | 25 mai 2023 A | 1 792 518 | 0 | 0 | $0 |
| Niall O'Donnell, Ph.D. | Administrateur | 25 mai 2023 A | 1 326 305 | 0 | 0 | $0 |
| Tiba Aynechi | Administrateur | 25 mai 2023 A | — | 0 | 0 | $0 |
| Moghrabi Dina Chaya | Administrateur | 25 mai 2022 A | 2 161 022 | 0 | 0 | $0 |
| Jonas Hansson | Administrateur | 14 octobre 2020 C | 2 033 621 | 0 | 0 | $0 |
| Parkman Healthcare Partners LLC | Détenteur de 10% | 6 octobre 2025 S | 1 050 | 1 | 2 | $-336 |
| Novo Holdings A/S | Détenteur de 10% | 21 mars 2024 S | 2 550 000 | 0 | 0 | $0 |
| Michael G Grey | — | 21 mai 2026 A | — | 0 | 0 | $0 |
| Daniel K Spiegelman | — | 21 mai 2026 A | — | 0 | 0 | $0 |
| HealthCap VIII, L.P. | — | 14 octobre 2020 C | 2 033 621 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 6 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| HealthCap VIII, L.P., HealthCap VIII GP LLC ×4 dépôts | 9 octobre 2025 | 3,40% | Amendement | — | SEC |
| RiverVest Venture Fund III, L.P., RiverVest Venture Fund III (Ohio), L.P., RiverVest Venture Partners III (Ohio), LLC, RiverVest Venture Partners III, L.P., RiverVest Venture Partners III, LLC, RiverVest Venture Fund IV, L.P., RiverVest Venture Partners IV, L.P., RiverVest Venture Partners IV, LLC, John P. McKearn, Ph.D., Jay Schmelter, Thomas C. Melzer, Niall O'Donnell, Ph.D. | 10 janvier 2025 | 4,20% | Amendement | — | SEC |
| Novo Holdings A/S ×9 dépôts | 28 mars 2024 | — | Dépôt initial | — | SEC |
| Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée | 30 mai 2023 | — | Dépôt initial | — | SEC |
| Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée | 23 octobre 2020 | — | Dépôt initial | Investissement passif | SEC |
| Abingworth LLP, Abingworth Bioventures VII, LP | 16 octobre 2020 | — | Dépôt initial | Campagne de conseil d'administration | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 13 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| DFAS · Dimensional ETF Trust | 0,00% | 1 283 NS | 30 avril 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 681 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWV · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| IWN · iShares Trust | — | — | 17 août 2026 | Quotidien |
| IWO · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWM · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWC · iShares Trust | — | — | 18 août 2026 | Quotidien |
| QQQS · Invesco Exchange-Traded Fund Trust … | — | — | 20 juillet 2026 | Quotidien |