WVE Wave Life Sciences Ltd. - Ordinary Shares
À propos de Wave Life Sciences Ltd. - Ordinary Shares Présentation de l'entreprise depuis Wikipedia
WVE Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
WVE Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
WVE Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 6 30,0%
- Achat 13 65,0%
- Conserver 1 5,0%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
16 analystes · 2026-08-17Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.34 | $-0.31 | -0.03% |
| 31 mars 2026 | $-0.13 | $-0.33 | 0.20% |
| 31 décembre 2025 | $-0.30 | $-0.27 | -0.03% |
| 30 septembre 2025 | $-0.32 | $-0.30 | -0.02% |
| 30 juin 2025 | $-0.31 | $-0.29 | -0.02% |
| 31 mars 2025 | $-0.29 | $-0.26 | -0.03% |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $43M | $108M | $113M | $4M | $41M | $20M | $16M | $14M | $4M | $1M | $152.0K | |
| R&D Expense | $183M | $160M | $130M | $116M | $122M | $131M | $175M | $134M | $79M | $41M | $9M | |
| SG&A Expense | $75M | $59M | $51M | $51M | $46M | $43M | $49M | $40M | $27M | $16M | $10M | |
| Operating Expenses | $258M | $219M | $181M | $166M | $168M | $173M | $224M | $174M | $106M | $57M | $19M | |
| Operating Income | $-215M | $-110M | $-68M | $-163M | $-127M | $-153M | $-208M | $-160M | $-102M | $-56M | $-19M | |
| Other Non-op | $527.0K | $3M | $2M | $7.0K | $5M | $2M | $10M | $10M | $-331.0K | $-50.0K | $56.0K | |
| Pretax Income | $-204M | $-97M | $-58M | $-161M | $-122M | $-151M | $-194M | $-147M | $-101M | $-55M | $-19M | |
| Income Tax | $0 | $0 | $-677.0K | $681.0K | $-204.0K | $-841.0K | $0 | $69.0K | $842.0K | $482.0K | $44.0K | |
| Net Income | $-204M | $-97M | $-58M | $-162M | $-122M | $-150M | $-194M | $-147M | $-102M | $-56M | $-19M | |
| EPS (Basic) | $-1.21 | $-0.70 | $-0.54 | $-2.05 | $-2.36 | · | · | · | · | · | · | |
| EPS (Diluted) | $-1.21 | $-0.70 | $-0.54 | $-2.05 | $-2.36 | · | · | · | · | · | · | |
| Shares (Basic) | 168,649,795 | 138,277,468 | 106,097,268 | 78,855,810 | 51,825,566 | · | · | · | · | · | · | |
| Shares (Diluted) | 168,649,795 | 138,277,468 | 106,097,268 | 78,855,810 | 51,825,566 | · | · | · | · | · | · |
Bilan 23
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $602M | $302M | $200M | $88M | $151M | $184M | $147M | $175M | $143M | $150M | $161M | |
| Receivables | $1M | $1M | $21M | · | · | $30M | $20M | $10M | $1M | · | · | |
| Prepaid Expense | $8M | $10M | $10M | $8M | $7M | $10M | $10M | $7M | $7M | $1M | $146.0K | |
| Other Current Assets | $3M | $7M | $4M | $2M | $5M | $5M | $9M | $11M | · | · | · | |
| Current Assets | $615M | $320M | $235M | $99M | $163M | $230M | $185M | $202M | $150M | $152M | $161M | |
| PP&E (Net) | $7M | $10M | $13M | $17M | $22M | $29M | $36M | $40M | $27M | $9M | $3M | |
| PP&E (Gross) | $57M | $56M | $56M | $55M | $54M | $54M | $53M | $49M | $32M | $11M | $4M | |
| Accum. Depreciation | $50M | $46M | $43M | $38M | $32M | $25M | $17M | $10M | $4M | $2M | $2M | |
| Other Non-current Assets | $16.0K | $55.0K | $156.0K | · | · | · | · | · | · | · | · | |
| Total Assets | $638M | $352M | $275M | $146M | $207M | $279M | $284M | $296M | $182M | $165M | $165M | |
| Accounts Payable | $16M | $16M | $13M | $17M | $7M | $14M | $9M | $13M | $8M | $5M | $3M | |
| Accrued Liabilities | $7M | $5M | $2M | $4M | $4M | $2M | $5M | $6M | $3M | · | · | |
| Current Liabilities | $95M | $111M | $186M | $72M | $64M | $121M | $118M | $130M | $18M | $12M | $4M | |
| Capital Leases | $9M | $18M | $25M | $32M | $25M | $26M | $29M | · | · | $16.0K | $78.0K | |
| Other Non-current Liabilities | · | · | · | $190.0K | · | $474.0K | $2M | $2M | $2M | $796.0K | $163.0K | |
| Total Liabilities | $112M | $135M | $227M | $184M | $167M | $189M | $213M | $215M | $34M | $22M | $4M | |
| Common Stock | $1.62B | $1.18B | $935M | $803M | $750M | $694M | $540M | $375M | $310M | $216M | $185M | |
| Paid-in Capital | $228M | $156M | $129M | $119M | $88M | $72M | $57M | $38M | $22M | $10M | $3M | |
| Retained Earnings | $-1.33B | $-1.12B | $-1.02B | $-967M | $-806M | $-683M | $-533M | $-340M | $-193M | $-90M | $-35M | |
| AOCI | $-250.0K | $-262.0K | $-124.0K | $-29.0K | $181.0K | $389.0K | $267.0K | $153.0K | $116.0K | $-291.0K | $41.0K | |
| Stockholders' Equity | $518M | $210M | $40M | $-45M | $32M | $83M | $64M | $73M | $140M | $135M | $153M | |
| Liabilities + Equity | $638M | $352M | $275M | $146M | $207M | $279M | $284M | $296M | $182M | $165M | $165M | |
| Shares Outstanding | 187,660,263 | 153,037,286 | 119,162,234 | 86,924,643 | 59,841,116 | 48,778,678 | 34,340,690 | 29,472,197 | 27,829,079 | 23,502,169 | 21,551,423 |
Flux de trésorerie 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | · | · | $2M | $784.0K | $594.0K | |
| Stock-based Comp | · | · | · | · | · | · | · | · | · | · | $4M | |
| Deferred Tax | $0 | $0 | $0 | · | · | · | · | · | $908.0K | $-698.0K | $36.0K | |
| Operating Cash Flow | $-187M | $-151M | $-19M | $-128M | $-89M | $-116M | $-188M | $-23M | $-84M | $-32M | $-13M | |
| CapEx | $718.0K | $938.0K | $1M | $1M | $560.0K | $1M | $4M | $10M | $19M | $6M | $2M | |
| Investing Cash Flow | $-718.0K | $-938.0K | $-1M | $-1M | $-560.0K | $-1M | $-4M | $-10M | $-19M | $-6M | · | |
| Stock Issued | · | · | $94M | $51M | · | $94M | $162M | $60M | $94M | $30M | $12M | |
| Financing Cash Flow | $488M | $254M | $133M | $67M | $56M | $155M | $164M | $65M | $94M | $29M | · | |
| Net Change in Cash | $300M | $102M | $112M | $-62M | $-34M | $37M | $-28M | $32M | $-8M | $-8M | $160M | |
| Taxes Paid | · | · | · | · | · | · | · | · | $-11.0K | $554.0K | · |
Taux de croissance 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -60.6% | -4.4% | 3005.1% | -91.1% | 104.0% | · | · | · | · | · | · | |
| Revenue CAGR 3Y | 127.1% | 38.3% | 78.0% | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 16.3% | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $43M | $108M | $113M | $4M | $41M | $20M | $16M | $14M | $4M | $1M | $152.0K | |
| Net Income TTM | $-204M | $-97M | $-58M | $-162M | $-122M | $-150M | $-194M | $-147M | $-102M | $-56M | $-19M | |
| P/E | -14.0 | -17.7 | -9.4 | -3.4 | -1.3 | · | · | · | · | · | · | |
| P / Tangible Book | 6.2 | 9.0 | 15.2 | · | 5.8 | 4.6 | · | · | · | · | · | |
| Earnings Yield | -7.1% | -5.7% | -10.7% | -29.3% | -75.2% | · | · | · | · | · | · |
Compte de résultat 15
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $2M | $38M | · | · | $9M | $9M | · | · | $20M | $13M | $49M | $22M | $13M | $285.0K | $375.0K | $2M | |
| R&D Expense | $51M | $47M | $53M | $46M | $43M | $41M | $45M | $41M | $40M | $33M | $32M | $33M | $31M | $28M | $30M | $27M | |
| SG&A Expense | $25M | $22M | $21M | $18M | $18M | $18M | $16M | $15M | $14M | $14M | $13M | $12M | $12M | $12M | $13M | $12M | |
| Operating Expenses | $76M | $70M | $74M | $64M | $61M | $59M | $61M | $56M | $55M | $47M | $45M | $46M | $43M | $39M | $43M | $40M | |
| Operating Income | $-74M | $-31M | $-56M | $-56M | $-53M | $-50M | $23M | $-64M | $-35M | $-34M | $4M | $-23M | $-30M | $-39M | $-42M | $-38M | |
| Interest Income | $5M | $5M | · | $2M | $2M | $3M | · | $2M | $2M | $3M | · | · | · | · | · | · | |
| Other Non-op | $-275.0K | $-80.0K | $234.0K | $324.0K | $-82.0K | $51.0K | $3M | $337.0K | $-18.0K | $365.0K | $171.0K | $118.0K | $1M | $-701.0K | $744.0K | $254.0K | |
| Pretax Income | $-69M | $-26M | $-53M | $-54M | $-50M | $-47M | $29M | $-62M | $-33M | $-32M | $7M | $-21M | $-27M | $-39M | $-41M | $-38M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $-677.0K | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-69M | $-26M | $-53M | $-54M | $-50M | $-47M | $29M | $-62M | $-33M | $-32M | $7M | $-21M | $-27M | $-39M | $-41M | $-38M | |
| EPS (Basic) | $-0.34 | $-0.13 | $-0.29 | $-0.32 | $-0.31 | $-0.29 | $0.26 | $-0.47 | $-0.25 | $-0.24 | $0.07 | $-0.20 | $-0.27 | $-0.42 | $-0.62 | $-0.62 | |
| EPS (Diluted) | $-0.34 | $-0.13 | $-0.29 | $-0.32 | $-0.31 | $-0.29 | $0.26 | $-0.47 | $-0.25 | $-0.24 | $0.07 | $-0.20 | $-0.27 | $-0.42 | $-0.62 | $-0.62 | |
| Shares (Basic) | 204,008,712 | 200,167,869 | -325,604,079 | 167,739,208 | 163,987,640 | 162,572,026 | -253,084,680 | 132,563,467 | 129,527,003 | 129,271,678 | 106,025,063 | 105,462,414 | 102,056,712 | 93,900,484 | 66,479,293 | 60,516,616 | |
| Shares (Diluted) | 204,008,712 | 200,167,869 | -325,604,079 | 167,739,208 | 163,987,640 | 162,572,026 | -253,084,680 | 132,563,467 | 129,527,003 | 129,271,678 | 106,975,231 | 105,462,414 | 102,056,712 | 93,900,484 | 66,479,293 | 60,516,616 | |
| EBITDA | $-74M | $-31M | · | $-56M | $-53M | $-50M | · | $-64M | $-35M | $-34M | $4M | $-23M | $-30M | $-39M | $-42M | $-38M |
Bilan 24
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $368M | $545M | $602M | $196M | $208M | $243M | $302M | $311M | $154M | $181M | $140M | $173M | $208M | $97M | $123M | $62M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | · | · | $25M | $25M | $50M | |
| Receivables | $888.0K | $0 | $1M | $10M | $2M | · | $1M | $0 | $1M | $0 | $7M | · | · | · | · | · | |
| Prepaid Expense | $12M | $13M | $8M | $7M | $7M | $8M | $10M | $11M | $12M | $11M | $8M | $9M | $9M | $7M | $5M | $7M | |
| Other Current Assets | $4M | $3M | $3M | $3M | $7M | $7M | $7M | $3M | $5M | $5M | $4M | $3M | $3M | $2M | $7M | $6M | |
| Current Assets | $508M | $561M | $615M | $215M | $224M | $258M | $320M | $325M | $172M | $197M | $159M | $185M | $220M | $131M | $160M | $124M | |
| PP&E (Net) | $7M | $7M | $7M | $8M | $9M | $10M | $10M | $11M | $12M | $12M | $14M | $15M | $16M | $19M | $20M | $21M | |
| PP&E (Gross) | · | · | $57M | · | · | · | $56M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | $51M | $50M | $50M | $49M | $48M | $47M | $46M | $45M | $44M | $44M | $42M | $40M | $39M | · | · | · | |
| Other Non-current Assets | $667.0K | $386.0K | $16.0K | $22.0K | $728.0K | $448.0K | $55.0K | · | · | · | · | · | · | · | · | · | |
| Total Assets | $558M | $584M | $638M | $241M | $252M | $288M | $352M | $359M | $209M | $235M | $200M | $230M | $267M | $182M | $213M | $167M | |
| Accounts Payable | $20M | $19M | $16M | $14M | $15M | $14M | $16M | $13M | $18M | $12M | $13M | $12M | $12M | $16M | $11M | $10M | |
| Accrued Liabilities | $5M | $5M | $7M | $5M | $3M | $2M | $5M | $3M | $2M | $2M | $3M | $3M | $2M | $2M | $3M | $3M | |
| Current Liabilities | $51M | $50M | $95M | $86M | $87M | $87M | $111M | $171M | $173M | $166M | $100M | $140M | $133M | $64M | $64M | $58M | |
| Capital Leases | $40M | $7M | $9M | $11M | $14M | $16M | $18M | $20M | $22M | $24M | $27M | $29M | $31M | $34M | $35M | $24M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | $190.0K | $190.0K | · | · | $868.0K | |
| Total Liabilities | $105M | $72M | $112M | $109M | $105M | $109M | $135M | $209M | $204M | $202M | $233M | $274M | $294M | $178M | $174M | $160M | |
| Common Stock | $1.63B | $1.63B | $1.62B | $1.22B | $1.19B | $1.18B | $1.18B | $1.14B | $951M | $950M | $841M | $840M | $838M | $803M | $802M | $751M | |
| Paid-in Capital | $248M | $237M | $228M | $174M | $168M | $161M | $156M | $153M | $136M | $132M | $127M | $125M | $122M | $117M | $113M | $92M | |
| Retained Earnings | $-1.42B | $-1.35B | $-1.33B | $-1.27B | $-1.22B | $-1.17B | $-1.12B | $-1.15B | $-1.09B | $-1.06B | $-1.01B | $-1.02B | $-995M | $-924M | $-885M | $-843M | |
| AOCI | $-172.0K | $-254.0K | $-250.0K | $-190.0K | $-161.0K | $-204.0K | $-262.0K | $-159.0K | $-279.0K | $-198.0K | $-182.0K | $-150.0K | $-50.0K | $-123.0K | $-47.0K | $95.0K | |
| Stockholders' Equity | $454M | $512M | $518M | $125M | $139M | $172M | $210M | $142M | $-3M | $25M | $-40M | $-52M | $-35M | $-5M | $31M | $-53.0K | |
| Liabilities + Equity | $558M | $584M | $638M | $241M | $252M | $288M | $352M | $359M | $209M | $235M | $200M | $230M | $267M | $182M | $213M | $167M | |
| Shares Outstanding | 193,277,622 | 192,337,566 | 187,660,263 | 160,288,481 | 155,673,292 | 154,093,313 | 153,037,286 | 148,392,939 | 122,479,289 | 122,321,384 | 99,011,901 | 98,566,816 | 98,104,844 | 86,841,523 | 86,724,658 | 60,859,968 |
Flux de trésorerie 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | $-54M | $-60M | $-34M | $-45M | $-46M | $-63M | $-44M | $-46M | $-27M | $-33M | $-34M | $-37M | $86M | $-26M | $-29M | $-40M | |
| CapEx | $884.0K | $438.0K | $-1.0K | $248.0K | $306.0K | $165.0K | $86.0K | $383.0K | $52.0K | $417.0K | $198.0K | $72.0K | $489.0K | $457.0K | $492.0K | $208.0K | |
| Investing Cash Flow | $-123M | $-438.0K | $1.0K | $-248.0K | $-306.0K | $-165.0K | $-86.0K | $-383.0K | $-52.0K | $-417.0K | $-198.0K | $-72.0K | $-489.0K | $-501.0K | $25M | $-50M | |
| Stock Issued | · | · | · | · | · | · | · | $174M | $0 | $14M | $-35M | $-35M | $0 | $-229.0K | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $14M | · | · | $35M | · | · | · | |
| Financing Cash Flow | $330.0K | $3M | $440M | $33M | $12M | $4M | $35M | $204M | $653.0K | $15M | $2M | $2M | $35M | $17.0K | $66M | $1M | |
| Net Change in Cash | $-177M | $-57M | $406M | $-12M | $-35M | $-59M | $-9M | $157M | $-27M | $-19M | $-33M | $-36M | $120M | $-26M | $61M | $-89M | |
| Free Cash Flow | · | $-60M | · | · | · | $-63M | · | · | · | $-34M | · | · | $85M | · | · | $-40M |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -3248.3% | -81.8% | · | · | -606.5% | -542.8% | · | · | -177.7% | -274.8% | 9.0% | -106.2% | -234.2% | -13648.8% | -11243.7% | -2176.8% | |
| Net Margin | -3052.6% | -68.2% | · | · | -580.2% | -510.9% | · | · | -167.2% | -251.7% | 14.7% | -95.5% | -212.0% | -13685.6% | -11012.3% | -2160.8% | |
| Pretax Margin | -3052.6% | -68.2% | · | · | -580.2% | -510.9% | · | · | -167.2% | -251.7% | 13.4% | -95.5% | -212.0% | -13685.6% | -11012.3% | -2160.8% | |
| EBITDA Margin | -3248.3% | -81.8% | · | · | -606.5% | -542.8% | · | · | -177.7% | -274.8% | 9.0% | -106.2% | -234.2% | -13648.8% | -11243.7% | -2176.8% | |
| ROA | -17.1% | -6.0% | · | -17.9% | -21.9% | -17.9% | · | -22.1% | -15.0% | -12.6% | 3.8% | -9.5% | -12.6% | -20.4% | -19.7% | -18.4% | |
| ROE | -23.4% | -7.6% | · | -40.5% | -74.3% | -47.5% | · | -122.2% | 119.3% | 676.9% | -32.2% | 203.2% | 157.7% | -307.3% | -156.5% | -143.3% | |
| ROIC | -16.3% | -6.1% | · | -45.2% | -37.9% | -29.0% | · | -45.1% | 1006.5% | -135.7% | -12.1% | 45.4% | 87.2% | 860.8% | -136.2% | 71875.5% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 10.0 | 11.3 | · | 2.5 | 2.6 | 3.0 | · | 1.9 | 1.0 | 1.2 | 1.6 | 1.3 | 1.7 | 2.0 | 2.5 | 2.1 | |
| Quick Ratio | 7.3 | 10.9 | · | 2.4 | 2.4 | 2.8 | · | 1.8 | 0.9 | 1.1 | 1.5 | 1.2 | 1.6 | 1.9 | 2.3 | 1.9 |
Efficacité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.1 | · | · | 0.0 | 0.0 | · | · | 0.1 | 0.0 | 0.3 | 0.1 | 0.1 | 0.0 | 0.0 | 0.0 | |
| Receivables Turnover | 1.8 | · | · | · | 6.0 | · | · | · | 30.5 | 0.8 | 3.3 | · | · | · | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | · | · | $104M | $104M | $97M | $85M | $36M | $15M | $39M | $41M | · | |
| Net Income TTM | $-200M | $-177M | · | $-213M | $-192M | $-173M | · | $-119M | $-78M | $-73M | $-80M | $-129M | $-146M | $-124M | $-124M | $-125M | |
| Market Cap | $1.12B | $1.39B | · | $1.17B | $1.01B | $1.25B | · | $1.22B | $611M | $755M | $569M | $359M | $425M | $313M | $282M | $122M | |
| P/E | -5.3 | -6.9 | · | -5.3 | -4.9 | -6.5 | · | -9.2 | -8.0 | -9.6 | -7.0 | -2.4 | -2.2 | -2.0 | -1.5 | · | |
| P/S | · | · | · | · | · | · | · | 11.8 | 5.9 | 7.8 | 6.7 | 10.1 | 27.7 | 8.1 | 6.8 | · | |
| P/B | 2.5 | 2.7 | · | 9.4 | 7.3 | 7.2 | · | 8.6 | -175.8 | 29.7 | -14.1 | -6.9 | -12.2 | -69.4 | 9.1 | -2296.6 | |
| P / Tangible Book | 2.5 | 2.7 | · | 9.4 | 7.3 | 7.2 | · | 8.6 | · | 29.7 | · | · | · | · | 9.1 | · | |
| P / Cash Flow | · | -23.4 | · | · | · | -19.8 | · | · | · | -22.6 | · | · | 5.0 | · | · | -3.1 | |
| P / FCF | · | -23.2 | · | · | · | -19.7 | · | · | · | -22.3 | · | · | 5.0 | · | · | -3.0 | |
| Earnings Yield | -18.9% | -14.5% | · | -19.0% | -20.3% | -15.5% | · | -10.8% | -12.4% | -10.4% | -14.3% | -41.5% | -44.6% | -49.3% | -65.8% | · |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $43M | $108M | $113M | $4M | $41M |
| Résultat net | $-204M | $-97M | $-58M | $-162M | $-122M |
| BPA dilué | $-1.21 | $-0.70 | $-0.54 | $-2.05 | $-2.36 |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 264 déclarants · $892.5M total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 56 (+5 vs T. préc.) | 37 (+1 vs T. préc.) | 93 (-18 vs T. préc.) | 59 (+4 vs T. préc.) | +16.8M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $156 727 684 | 26 975 505 | 17,56% | Actions |
| GSK plc | $106 007 465 | 18 245 691 | 11,88% | Actions |
| MAVERICK CAPITAL LTD | $59 715 848 | 10 278 115 | 6,69% | Actions |
| Driehaus Capital Management LLC | $31 624 661 | 5 443 143 | 3,54% | Actions |
| PRIMECAP MANAGEMENT CO/CA/ | $31 110 354 | 5 354 622 | 3,49% | Actions |
| 683 Capital Management, LLC | $28 759 500 | 4 950 000 | 3,22% | Actions |
| STATE STREET CORP | $28 116 432 | 4 839 317 | 3,15% | Actions |
| READYSTATE ASSET MANAGEMENT LP | $27 464 678 | 4 727 139 | 3,08% | Actions |
| M28 Capital Management LP | $26 657 930 | 4 588 284 | 2,99% | Actions |
| TWO SIGMA INVESTMENTS, LP | $21 541 656 | 3 707 686 | 2,41% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $19 277 729 | 3 317 246 | 2,16% | Actions |
| FMR LLC | $17 099 004 | 2 943 030 | 1,92% | Actions |
| ALGERT GLOBAL LLC | $16 370 343 | 2 817 615 | 1,83% | Actions |
| Qube Research & Technologies Ltd | $16 128 560 | 2 776 000 | 1,81% | Actions |
| Squarepoint Ops LLC | $14 765 778 | 2 541 442 | 1,65% | Actions |
| VANGUARD GROUP INC | $14 386 233 | 846 249 | 1,61% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12 263 463 | 2 110 751 | 1,37% | Actions |
| MORGAN STANLEY | $12 000 799 | 2 065 542 | 1,34% | Actions |
| Pfizer Inc | $10 931 250 | 1 875 000 | 1,22% | Actions |
| MILLENNIUM MANAGEMENT LLC | $10 523 548 | 1 811 282 | 1,18% | Actions |
| D. E. Shaw & Co., Inc. | $10 296 645 | 1 772 228 | 1,15% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $10 175 651 | 1 751 403 | 1,14% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $9 920 932 | 1 746 643 | 1,11% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $9 903 261 | 1 704 520 | 1,11% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $9 201 210 | 1 583 685 | 1,03% | Actions |
| GOLDMAN SACHS GROUP INC | $8 877 262 | 1 527 928 | 0,99% | Actions |
| Point72 Asset Management, L.P. | $8 627 786 | 1 484 989 | 0,97% | Actions |
| RTW INVESTMENTS, LP | $7 843 500 | 1 350 000 | 0,88% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7 114 025 | 1 224 445 | 0,80% | Actions |
| EMERALD ADVISERS, LLC | $7 111 237 | 1 223 965 | 0,80% | Actions |
| BlackRock, Inc. | $5 539 777 | 953 490 | 0,62% | Actions |
| SymBiosis Capital Partners, LLC | $5 437 500 | 750 000 | 0,61% | Actions |
| Pictet Asset Management Holding SA | $5 330 146 | 917 409 | 0,60% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $5 157 403 | 887 677 | 0,58% | Actions |
| Aberdeen Group plc | $5 092 221 | 876 458 | 0,57% | Actions |
| EMERALD MUTUAL FUND ADVISERS TRUST | $4 926 874 | 847 999 | 0,55% | Actions |
| BAKER BROS. ADVISORS LP | $4 779 527 | 822 638 | 0,54% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $4 712 241 | 811 057 | 0,53% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $4 268 874 | 734 746 | 0,48% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $3 708 360 | 638 272 | 0,42% | Actions |
| Y-Intercept (Hong Kong) Ltd | $3 544 646 | 610 094 | 0,40% | Actions |
| Susquehanna Portfolio Strategies, LLC | $3 533 607 | 608 194 | 0,40% | Actions |
| TANG CAPITAL MANAGEMENT LLC | $3 486 000 | 600 000 | 0,39% | Actions |
| Walleye Capital LLC | $3 401 482 | 585 453 | 0,38% | Actions |
| CITADEL ADVISORS LLC | $2 789 695 | 480 154 | 0,31% | Actions |
| BANK OF AMERICA CORP /DE/ | $2 569 042 | 442 176 | 0,29% | Actions |
| XTX Topco Ltd | $2 556 011 | 439 933 | 0,29% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2 375 674 | 408 894 | 0,27% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $2 319 398 | 399 208 | 0,26% | Actions |
| Trexquant Investment LP | $2 208 782 | 380 169 | 0,25% | Actions |
| HSBC HOLDINGS PLC | $2 172 683 | 370 449 | 0,24% | Actions |
| Woodline Partners LP | $2 036 585 | 350 531 | 0,23% | Actions |
| Ishara Investments LP | $1 905 680 | 328 000 | 0,21% | Actions |
| BARCLAYS PLC | $1 766 839 | 304 103 | 0,20% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 739 514 | 299 400 | 0,19% | Actions |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1 599 313 | 275 269 | 0,18% | Actions |
| JPMORGAN CHASE & CO | $1 543 989 | 265 614 | 0,17% | Actions |
| Swiss National Bank | $1 514 086 | 260 600 | 0,17% | Actions |
| ExodusPoint Capital Management, LP | $1 458 728 | 251 072 | 0,16% | Actions |
| Privium Fund Management B.V. | $1 400 268 | 241 010 | 0,16% | Actions |
| F/m Investments LLC | $1 365 844 | 235 085 | 0,15% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1 339 112 | 230 484 | 0,15% | Actions |
| Newtyn Management, LLC | $1 249 150 | 215 000 | 0,14% | Actions |
| TD Asset Management Inc | $1 127 291 | 194 026 | 0,13% | Actions |
| ALPS ADVISORS INC | $1 125 780 | 193 766 | 0,13% | Actions |
| RHUMBLINE ADVISERS | $1 125 195 | 193 667 | 0,13% | Actions |
| Sofinnova Investments, Inc. | $1 099 560 | 189 253 | 0,12% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 052 744 | 145 206 | 0,12% | Actions |
| Elmind Capital, LP | $1 033 285 | 177 846 | 0,12% | Actions |
| ADAR1 Capital Management, LLC | $929 600 | 160 000 | 0,10% | Actions |
| Bank of New York Mellon Corp | $911 560 | 156 895 | 0,10% | Actions |
| ALLIANCEBERNSTEIN L.P. | $904 293 | 124 730 | 0,10% | Actions |
| Burkehill Global Management, LP | $871 500 | 150 000 | 0,10% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $842 450 | 145 000 | 0,09% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $836 692 | 144 009 | 0,09% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $830 981 | 143 026 | 0,09% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $801 995 | 138 037 | 0,09% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $775 635 | 133 500 | 0,09% | Option d'achat |
| CITIGROUP INC | $680 287 | 117 089 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $675 395 | 116 247 | 0,08% | Actions |
| James J. Burns & Company, LLC | $666 988 | 114 800 | 0,07% | Actions |
| IEQ CAPITAL, LLC | $618 451 | 106 446 | 0,07% | Actions |
| Cetera Investment Advisers | $609 341 | 104 878 | 0,07% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $608 336 | 104 705 | 0,07% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $604 211 | 103 995 | 0,07% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $593 782 | 102 200 | 0,07% | Option de vente |
| Mariner, LLC | $593 759 | 102 195 | 0,07% | Actions |
| Bridgefront Capital, LLC | $589 448 | 101 454 | 0,07% | Actions |
| UBS Group AG | $531 034 | 91 400 | 0,06% | Option d'achat |
| MetLife Investment Management, LLC | $513 587 | 88 397 | 0,06% | Actions |
| Ikarian Capital, LLC | $495 507 | 85 285 | 0,06% | Actions |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $476 000 | 81 955 | 0,05% | Actions |
| Entropy Technologies, LP | $467 409 | 80 449 | 0,05% | Actions |
| EXCHANGE TRADED CONCEPTS, LLC | $467 310 | 80 432 | 0,05% | Actions |
| Quadrature Capital Ltd | $459 368 | 79 065 | 0,05% | Actions |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $451 007 | 77 626 | 0,05% | Actions |
| a16z Perennial Management, L.P. | $450 966 | 77 619 | 0,05% | Actions |
| MARSHALL WACE, LLP | $443 645 | 76 359 | 0,05% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $432 450 | 74 432 | 0,05% | Actions |
| FEDERATED HERMES, INC. | $408 304 | 70 276 | 0,05% | Actions |
Initiés de la société 21 initiés · 8 dirigeants · 9 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Paul Bolno | President and CEO | 5 février 2026 A | 275 520 | 0 | 2 | $-2 336 201 |
| Kyle Moran | Chief Financial Officer | 5 février 2026 A | 134 385 | 0 | 7 | $-4 151 988 |
| David G Gaiero | Interim CFO | 3 mars 2020 A | 6 392 | 0 | 0 | $0 |
| Keith Regnante | Chief Financial Officer | 7 mars 2019 A | 29 186 | 0 | 0 | $0 |
| Chris Francis | SVP, Corporate Development, Head of Emerging Areas | 26 février 2026 M | 61 867 | 0 | 14 | $-7 103 233 |
| Chandra Vargeese | Chief Technology Officer, Head of Platform Discovery Sciences | 5 février 2026 A | 408 246 | 0 | 1 | $-43 417 |
| Michael A. Panzara | Chief Medical Officer, Head of Therapeutics Discovery and Development | 25 juillet 2022 A | 109 103 | 0 | 0 | $0 |
| Mark Baldry | Chief Commerical Officer | 5 août 2019 A | 39 000 | 0 | 0 | $0 |
| Gregory L. Verdine | Administrateur | 8 décembre 2025 S | 275 217 | 0 | 3 | $-369 461 |
| Christian O Henry | Administrateur | 8 décembre 2025 M | 12 700 | 0 | 4 | $-1 369 324 |
| Mark Corrigan | Administrateur | 8 décembre 2025 S | 28 815 | 0 | 2 | $-217 265 |
| Amy Pott | Administrateur | 18 août 2020 A | — | 0 | 0 | $0 |
| Peter Kolchinsky | Administrateur | 18 août 2020 A | — | 0 | 0 | $0 |
| Koji Miura | Administrateur | 15 août 2019 A | — | 0 | 0 | $0 |
| Masaharu Tanaka | Administrateur | 10 novembre 2016 A | — | 0 | 0 | $0 |
| Takeshi Wada | Administrateur | 10 novembre 2016 A | — | 0 | 0 | $0 |
| Adrian Rawcliffe | — | 12 août 2026 S | 0 | 0 | 3 | $-806 604 |
| Tan Aik Na | — | 11 août 2026 S | 24 968 | 0 | 10 | $-2 020 004 |
| Ken Takanashi | — | 11 août 2026 S | 20 079 | 0 | 1 | $-23 223 |
| Heidi L Wagner | — | 11 août 2026 M | 44 930 | 0 | 3 | $-231 070 |
| Roberto Guerciolini | — | 7 décembre 2016 M | 4 000 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 4 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×9 dépôts | 11 août 2026 | 16,80% | Amendement | — | SEC |
| Shin Nippon Biomedical Laboratories, Ltd., SNBL USA, Ltd., Ken Takanashi ×6 dépôts | 12 août 2022 | — | Dépôt initial | — | SEC |
| Kagoshima Shinsangyo Sousei Investment Limited Partnership, Kagoshima Development Co. Ltd. ×5 dépôts | 20 juillet 2022 | — | Dépôt initial | — | SEC |
| RA Capital Management, LLC, Peter Kolchinsky ×3 dépôts | 28 janvier 2019 | — | Dépôt initial | Investissement passif | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 28 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| GNOM · Global X Funds | 1,03% | 87 259 NS | 31 mai 2026 | N-PORT |
| PILL · Direxion Shares ETF Trust | 0,67% | 12 254 NS | 30 avril 2026 | N-PORT |
| IHE · iShares Trust | 0,20% | 541 635 SH | 8 août 2026 | Quotidien |
| IWC · iShares Trust | 0,19% | 463 783 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,07% | 1 158 886 SH | 8 août 2026 | Quotidien |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,05% | 111 824 SH | 8 août 2026 | Quotidien |
| IWN · iShares Trust | 0,05% | 1 196 960 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,03% | 60 562 NS | 30 avril 2026 | N-PORT |
| IWM · iShares Trust | 0,03% | 3 525 539 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 793 588 SH | 8 août 2026 | Quotidien |
| ISCV · iShares Trust | 0,02% | 18 901 SH | 8 août 2026 | Quotidien |
| ISCB · iShares Trust | 0,01% | 6 085 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,01% | 250 409 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 1 751 403 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,01% | 390 910 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,01% | 14 793 SH | 8 août 2026 | Quotidien |
| WSML · iShares Trust | 0,01% | 7 226 SH | 8 août 2026 | Quotidien |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 4 467 NS | 31 mai 2026 | N-PORT |
| IWO · iShares Trust | 0,00% | 86 005 SH | 8 août 2026 | Quotidien |
| DFAU · Dimensional ETF Trust | 0,00% | 43 085 NS | 30 avril 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 1 463 NS | 30 avril 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 10 250 NS | 30 avril 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 63 707 SH | 8 août 2026 | Quotidien |
| ITOT · iShares Trust | 0,00% | 248 385 SH | 8 août 2026 | Quotidien |
| DFAC · Dimensional ETF Trust | 0,00% | 74 011 NS | 30 avril 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 18 648 NS | 30 avril 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,00% | 10 069 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 11 431 SH | 8 août 2026 | Quotidien |