TYRA Tyra Biosciences, Inc. - Common Stock
$26,42
Harga · Agu 18, 2026
Fundamental per Agu 4, 2026
Rentang 52M
$10–$41
54% of range
Peringkat Analis
BUY
22 analysts
Target Harga
$51
+92% upside
P/E (TTM)
-13.1
ROE
-42.7%
Margin Laba Bersih
—
TYRA Cuplikan Saham Harga, kapitalisasi pasar, P/E, EPS, ROE, utang/ekuitas, kisaran 52 minggu
Harga
$26.42
Kapitalisasi Pasar
$1.42B
P/E (TTM)
-13.1
EPS (TTM)
$-2.01
Pendapatan (TTM)
—
Imbal Hasil Dividen
—
ROE
-42.7%
D/E Utang/Ekuitas
—
Rentang 52M
$10 – $41
TYRA Grafik Harga Saham OHLCV harian dengan indikator teknis — geser, perbesar, dan sesuaikan tampilan Anda
Configure
Kinerja 10 Tahun Tren Pendapatan, laba bersih, margin, dan EPS
Pendapatan & Laba Bersih
—
EPS
$-2.01
2021-12-31
→
2025-12-31
Arus Kas Bebas
$-95M
2021-12-31
→
2025-12-31
Margin
—
Valuasi Rasio P/E, P/S, P/B, EV/EBITDA — apakah sahamnya mahal atau murah?
Metrik
Tren 5 Tahun
TYRA
Median Rekan
P/E (TTM)
-13.1
—
P/B
5.5
2.7
Price / FCF (Harga / FCF)
-14.9
—
Profitabilitas Margin kotor, operasional, dan bersih; ROE, ROA, ROIC
Metrik
Tren 5 Tahun
TYRA
Median Rekan
ROA
-37.1%
-43.1%
ROE
-42.7%
-49.0%
Kesehatan Keuangan Utang, likuiditas, solvabilitas — kekuatan neraca
Metrik
Tren 5 Tahun
TYRA
Median Rekan
Current Ratio (Rasio Lancar)
14.7
9.0
Quick Ratio (Rasio Cepat)
4.3
—
Pertumbuhan Pertumbuhan Pendapatan, EPS, dan Laba Bersih: YoY, CAGR 3T, CAGR 5T
Metrik
Tren 5 Tahun
TYRA
Median Rekan
Efisiensi Modal Perputaran aset, perputaran persediaan, perputaran piutang
Metrik
Tren 5 Tahun
TYRA
Median Rekan
TYRA Konsensus Analis Opini analis bullish dan bearish, target harga 12 bulan, potensi kenaikan
BELI
22 analis
- Beli Kuat 9 40,9%
- Beli 11 50,0%
- Tahan 2 9,1%
- Jual 0 0,0%
- Jual Kuat 0 0,0%
Target Harga 12 Bulan
11 analis · 2026-08-16
Median
$53.00
Rata-rata
$50.82
← Di bawah semua target
$26.42
Rendah
$39.00
Tinggi
$59.00
Target median
$53.00
+100,6%
Target rata-rata
$50.82
+92,3%
Riwayat Pendapatan EPS aktual vs perkiraan, kejutan %, tingkat keberhasilan, tanggal pendapatan berikutnya
Kejutan Rata-rata
0.00%
| Periode | EPS Aktual | EPS Estimasi | Kejutan |
|---|---|---|---|
| 30 Juni 2026 | $-0.69 | $-0.66 | -0.03% |
| 31 Maret 2026 | $-0.64 | $-0.60 | -0.04% |
| 31 Des. 2025 | $-0.57 | $-0.54 | -0.03% |
| 30 Sep. 2025 | $-0.50 | $-0.51 | 0.01% |
| 30 Juni 2025 | $-0.47 | $-0.54 | 0.07% |
| 31 Maret 2025 | $-0.47 | $-0.50 | 0.03% |
Perbandingan rekan (sub-industri GICS) Metrik utama vs rekan sektor
| Ticker | Kapitalisasi Pasar | P/E | Pendapatan YoY | Margin Bersih | ROE | Margin Kotor |
|---|---|---|---|---|---|---|
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| RXRX | $2.16B | -2.8 | 26.9% | -863.4% | -62.9% | — |
| FBRX | $353M | -5.8 | 106.6% | -2555.2% | -86.9% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| BCAX | $953M | -6.7 | — | — | -33.0% | — |
| XNCR | $1.10B | -12.3 | 13.7% | -73.2% | -14.0% | — |
| JBIO | $761M | -4.8 | — | — | -47.7% | — |
| TRAX | — | — | — | — | — | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
Fundamental Lengkap Semua metrik per tahun — laporan laba rugi, neraca, arus kas
Laporan Laba Rugi 12
| Metrik | Tren | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $103M | $80M | $63M | $43M | $21M | $7M | |
| SG&A Expense | $30M | $24M | $17M | $16M | $6M | $2M | |
| Operating Expenses | $133M | $104M | $80M | $59M | $26M | $9M | |
| Operating Income | $-133M | $-104M | $-80M | $-59M | $-26M | $-9M | |
| Other Non-op | $13M | $18M | $11M | $4M | $-6.0K | $-39.0K | |
| Income Tax | $0 | $0 | $0 | $2.0K | $1.0K | $1.0K | |
| Net Income | $-120M | $-86M | $-69M | $-55M | $-26M | $-9M | |
| EPS (Basic) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| EPS (Diluted) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| Shares (Basic) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| Shares (Diluted) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| EBITDA | $-132M | $-104M | $-80M | $-59M | $-26M | · |
Neraca 19
| Metrik | Tren | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $77M | $92M | $58M | $251M | $302M | $15M | |
| Prepaid Expense | $9M | $6M | $8M | $6M | $2M | $57.0K | |
| Current Assets | $265M | $347M | $212M | $257M | $304M | $15M | |
| PP&E (Net) | $1M | $2M | $2M | $1M | $1M | $297.0K | |
| PP&E (Gross) | · | $3M | $2M | $2M | $1M | $340.0K | |
| Accum. Depreciation | · | $1M | $807.0K | $461.0K | $169.0K | $43.0K | |
| Other Non-current Assets | $9M | $7M | $5M | $4M | $312.0K | $21.0K | |
| Total Assets | $283M | $364M | $226M | $266M | $307M | $16M | |
| Accounts Payable | $1M | $590.0K | $5M | $1M | $599.0K | $664.0K | |
| Current Liabilities | $18M | $15M | $15M | $6M | $4M | $2M | |
| Capital Leases | $5M | $6M | $6M | $2M | $981.0K | $0 | |
| Other Non-current Liabilities | $0 | $3.0K | $46.0K | $169.0K | $367.0K | $140.0K | |
| Total Liabilities | $23M | $20M | $22M | $8M | $5M | $2M | |
| Common Stock | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $0 | |
| Retained Earnings | $-371M | $-251M | $-165M | $-96M | $-40M | $-14M | |
| AOCI | $393.0K | $770.0K | $381.0K | $0 | · | · | |
| Stockholders' Equity | $259M | $343M | $204M | $258M | $302M | $-14M | |
| Liabilities + Equity | $283M | $364M | $226M | $266M | $307M | $16M | |
| Shares Outstanding | 53,706,357 | 50,749,945 | 43,024,634 | 42,353,550 | 41,441,135 | 1,829,377 |
Arus Kas 9
| Metrik | Tren | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $546.0K | $519.0K | $357.0K | $296.0K | $140.0K | $47.0K | |
| Stock-based Comp | $28M | $23M | $14M | $11M | $3M | $439.0K | |
| Other Non-cash | $-4M | $-7M | $5M | $-6M | $-478.0K | · | |
| Operating Cash Flow | $-95M | $-70M | $-50M | $-50M | $-24M | $-8M | |
| CapEx | $141.0K | $664.0K | $770.0K | $559.0K | $661.0K | $312.0K | |
| Investing Cash Flow | $72M | $-98M | $-145M | $-559.0K | $-645.0K | $-312.0K | |
| Financing Cash Flow | $8M | $202M | $2M | $632.0K | $311M | $23M | |
| Net Change in Cash | $-15M | $34M | $-193M | $-50M | $287M | $15M | |
| Free Cash Flow | $-95M | $-70M | $-51M | $-51M | $-24M | · |
Profitabilitas 2
| Metrik | Tren | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -37.1% | -29.3% | -28.1% | -19.3% | -16.3% | · | |
| ROE | -42.7% | -24.5% | -32.4% | -21.1% | -8.6% | · |
Likuiditas & Solvabilitas 2
| Metrik | Tren | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 | · | |
| Quick Ratio | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 | · |
Valuasi (TTM) 8
| Metrik | Tren | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-120M | $-86M | $-69M | $-55M | $-26M | · | |
| Market Cap | $1.41B | $705M | $596M | $322M | $583M | · | |
| P/E | -13.1 | -9.2 | -8.5 | -5.8 | -7.4 | · | |
| P/B | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Tangible Book | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Cash Flow | -14.8 | -10.1 | -11.9 | -6.4 | -24.6 | · | |
| P / FCF | -14.8 | -10.0 | -11.7 | -6.3 | -23.9 | · | |
| Earnings Yield | -7.6% | -10.9% | -11.7% | -17.4% | -13.6% | · |
Laporan Laba Rugi 11
| Metrik | Tren | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $39M | $33M | $28M | $25M | $24M | $25M | $22M | $23M | $18M | $17M | $21M | $19M | $12M | $10M | $10M | $11M | |
| SG&A Expense | $10M | $9M | $8M | $7M | $7M | $7M | $8M | $6M | $6M | $5M | $5M | $5M | $4M | $4M | $10M | $173.0K | |
| Operating Expenses | $49M | $42M | $37M | $33M | $31M | $32M | $30M | $29M | $24M | $22M | $26M | $24M | $16M | $14M | $15M | $14M | |
| Operating Income | $-49M | $-42M | $-37M | $-33M | $-31M | $-32M | $-30M | $-29M | $-24M | $-22M | $-26M | $-24M | $-16M | $-14M | $-15M | $-14M | |
| Other Non-op | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $5M | $5M | $4M | $3M | $3M | $3M | $2M | $3M | $5.0K | |
| Net Income | $-46M | $-39M | $-34M | $-30M | $-28M | $-28M | $-26M | $-24M | $-19M | $-18M | $-23M | $-21M | $-13M | $-12M | $-13M | $-13M | |
| EPS (Basic) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| EPS (Diluted) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| Shares (Basic) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| Shares (Diluted) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| EBITDA | $-49M | $-42M | · | $-33M | $-31M | $-32M | · | $-29M | $-24M | $-22M | · | $-24M | $-16M | $-14M | · | $-14M |
Neraca 19
| Metrik | Tren | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $74M | $85M | $77M | $62M | $98M | $101M | $92M | $104M | $99M | $254M | $58M | $216M | $232M | $242M | $251M | $263M | |
| Prepaid Expense | $13M | $11M | $9M | $6M | $6M | $6M | $6M | $5M | $5M | $8M | $8M | $9M | $8M | $5M | $6M | $4M | |
| Current Assets | $367M | $395M | $265M | $281M | $302M | $325M | $347M | $366M | $379M | $391M | $212M | $225M | $241M | $247M | $257M | $267M | |
| PP&E (Net) | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | |
| PP&E (Gross) | · | · | · | · | · | $3M | · | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | · | · | · | · | · | $1M | · | $1M | $1M | $926.0K | $807.0K | $706.0K | $629.0K | $544.0K | $461.0K | $379.0K | |
| Other Non-current Assets | $9M | $10M | $9M | $13M | $11M | $10M | $7M | $6M | $5M | $5M | $5M | $5M | $866.0K | $4M | $4M | $4M | |
| Total Assets | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Accounts Payable | $2M | $4M | $1M | $2M | $2M | $2M | $590.0K | $1M | $2M | $3M | $5M | $2M | $1M | $1M | $1M | $3M | |
| Current Liabilities | $25M | $19M | $18M | $16M | $14M | $14M | $15M | $12M | $10M | $9M | $15M | $10M | $5M | $4M | $6M | $5M | |
| Capital Leases | $5M | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $2M | $2M | $3M | |
| Other Non-current Liabilities | · | · | $0 | $0 | $0 | $0 | $3.0K | $11.0K | $20.0K | $29.0K | $46.0K | $77.0K | $108.0K | $139.0K | $169.0K | $226.0K | |
| Total Liabilities | $30M | $24M | $23M | $21M | $19M | $20M | $20M | $18M | $16M | $15M | $22M | $16M | $11M | $6M | $8M | $8M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Retained Earnings | $-456M | $-411M | $-371M | $-337M | $-308M | $-279M | $-251M | $-226M | $-202M | $-183M | $-165M | $-142M | $-121M | $-108M | $-96M | $-83M | |
| AOCI | $-580.0K | $107.0K | $393.0K | $442.0K | $436.0K | $688.0K | $770.0K | $2M | $-184.0K | $-6.0K | $381.0K | · | · | · | $0 | · | |
| Stockholders' Equity | $354M | $388M | $259M | $281M | $302M | $324M | $343M | $362M | $376M | $390M | $204M | $222M | $239M | $249M | $258M | $268M | |
| Liabilities + Equity | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Shares Outstanding | 59,662,877 | 59,469,687 | 53,706,357 | 53,318,198 | 53,233,494 | 53,089,957 | 50,749,945 | 52,871,825 | 52,736,458 | 52,474,533 | 43,024,634 | 42,928,884 | 42,817,233 | 42,535,374 | 42,353,550 | 42,136,971 |
Arus Kas 11
| Metrik | Tren | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $138.0K | $138.0K | $132.0K | $131.0K | $140.0K | $143.0K | $144.0K | $127.0K | $126.0K | $122.0K | $102.0K | $86.0K | $89.0K | $83.0K | $82.0K | $82.0K | |
| Stock-based Comp | $10M | $8M | $8M | $8M | $6M | $6M | $7M | $8M | $4M | $4M | $4M | $4M | $3M | $2M | $3M | $1M | |
| Other Non-cash | · | $-1M | · | · | · | $-4M | · | · | · | $-8M | · | · | · | $-483.0K | · | · | |
| Operating Cash Flow | $-31M | $-33M | $-24M | $-22M | $-24M | $-25M | $-20M | $-18M | $-10M | $-22M | $-14M | $-17M | $-10M | $-10M | $-12M | $-12M | |
| CapEx | $66.0K | $88.0K | $57.0K | $39.0K | $31.0K | $14.0K | $6.0K | $52.0K | $470.0K | $136.0K | $603.0K | $83.0K | $43.0K | $41.0K | $21.0K | $48.0K | |
| Investing Cash Flow | $18M | $-120M | $34M | $-15M | $21M | $32M | $7M | $22M | $-145M | $18M | $-144M | $-83.0K | $-43.0K | $-41.0K | $-21.0K | $-48.0K | |
| Stock Issued | $0 | $148M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $148M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $160M | $5M | $647.0K | $583.0K | $2M | $706.0K | $743.0K | $373.0K | $200M | $324.0K | $467.0K | $370.0K | $376.0K | $3.0K | $364.0K | |
| Net Change in Cash | $-11M | $8M | $15M | $-37M | $-2M | $9M | $-12M | $4M | $-155M | $196M | $-158M | $-17M | $-9M | $-10M | $-12M | $-12M | |
| Free Cash Flow | · | $-33M | · | · | · | $-25M | · | · | · | $-22M | · | · | · | $-10M | · | · |
Profitabilitas 2
| Metrik | Tren | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -12.9% | -10.4% | · | -8.8% | -7.9% | -7.5% | · | -7.8% | -5.8% | -5.5% | · | -8.2% | -4.9% | -4.3% | · | -4.2% | |
| ROE | -13.9% | -11.1% | · | -9.3% | -8.3% | -7.9% | · | -8.2% | -6.1% | -5.7% | · | -8.6% | -5.1% | -4.4% | · | -4.3% |
Likuiditas & Solvabilitas 2
| Metrik | Tren | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 20.5 | · | 17.7 | 21.9 | 22.8 | · | 29.5 | 36.5 | 44.8 | · | 22.1 | 44.5 | 67.0 | · | 48.7 | |
| Quick Ratio | 3.0 | 4.4 | · | 3.9 | 7.2 | 7.1 | · | 8.4 | 9.6 | 29.2 | · | 21.3 | 43.0 | 65.6 | · | 48.0 |
Valuasi (TTM) 8
| Metrik | Tren | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-143M | $-125M | · | $-110M | $-99M | $-89M | · | $-82M | $-71M | $-64M | · | $-59M | $-53M | $-54M | · | $-49M | |
| Market Cap | $1.91B | $2.28B | · | $746M | $509M | $494M | · | $1.24B | $843M | $861M | · | $591M | $729M | $684M | · | $370M | |
| P/E | -13.9 | -18.4 | · | -7.6 | -5.7 | -6.0 | · | -15.0 | -10.9 | -11.5 | · | -10.0 | -13.6 | -12.4 | · | -5.1 | |
| P/B | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Tangible Book | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Cash Flow | · | -69.9 | · | · | · | -19.4 | · | · | · | -39.1 | · | · | · | -69.4 | · | · | |
| P / FCF | · | -69.7 | · | · | · | -19.4 | · | · | · | -38.8 | · | · | · | -69.1 | · | · | |
| Earnings Yield | -7.2% | -5.4% | · | -13.2% | -17.4% | -16.7% | · | -6.7% | -9.2% | -8.7% | · | -10.0% | -7.3% | -8.1% | · | -19.8% |
Laporan Keuangan Laporan laba rugi, neraca, arus kas — tahunan, 5 tahun terakhir
Laporan Laba Rugi
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Laba Bersih | $-120M | $-86M | $-69M | $-55M | $-26M |
| EPS Dilusian | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 |
Neraca
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Rasio Lancar | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 |
| Rasio Cepat | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 |
Arus Kas
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Arus Kas Bebas | $-95M | $-70M | $-51M | $-51M | $-24M |
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Pemilik institusional (13F) 182 pengaju · $1.9B total · Per tanggal 30 Juni 2026
Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.
Aktivitas institusional — Q2 2026 vs kuartal sebelumnya
| Posisi baru | Posisi yang keluar | Meningkat | Menurun | Perubahan bersih saham |
|---|---|---|---|---|
| 41 (-9 vs Kuartal sebelumnya) | 22 (+9 vs Kuartal sebelumnya) | 60 (+8 vs Kuartal sebelumnya) | 49 (+12 vs Kuartal sebelumnya) | +7.7M |
Dibandingkan dengan Q1 2026. Pengajuan Formulir 13F SEC jatuh tempo dalam waktu 45 hari setelah akhir kuartal ditambah kelonggaran singkat untuk pengaju terlambat — kuartal yang masih dalam jangka waktu tersebut dilewati demi pasangan terakhir yang dilaporkan sepenuhnya.
| Institusi | Nilai | Saham | % dari 13F yang dilacak | Tipe |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $389.624.083 | 12.198.625 | 20,33% | Saham |
| FMR LLC | $259.465.452 | 8.123.527 | 13,54% | Saham |
| Alta Partners Management Company, L.P. | $122.120.195 | 3.823.425 | 6,37% | Saham |
| Nextech Invest Ltd. | $113.501.505 | 3.553.585 | 5,92% | Saham |
| TCG Crossover Management, LLC | $103.772.421 | 3.248.980 | 5,42% | Saham |
| STATE STREET CORP | $68.363.354 | 2.140.368 | 3,57% | Saham |
| Commodore Capital LP | $59.887.500 | 1.875.000 | 3,13% | Saham |
| Paradigm Biocapital Advisors LP | $58.405.708 | 1.828.607 | 3,05% | Saham |
| Nextech Invest Ltd. | $56.376.468 | 4.055.861 | 2,94% | Saham |
| VANGUARD CAPITAL MANAGEMENT LLC | $48.179.797 | 1.508.447 | 2,51% | Saham |
| BVF INC/IL | $47.149.700 | 1.476.196 | 2,46% | Saham |
| VANGUARD GROUP INC | $36.938.081 | 1.405.024 | 1,93% | Saham |
| 5AM Venture Management, LLC | $32.875.778 | 1.029.298 | 1,72% | Saham |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $32.482.980 | 1.017.000 | 1,70% | Saham |
| Hood River Capital Management LLC | $32.475.794 | 1.016.775 | 1,69% | Saham |
| GEODE CAPITAL MANAGEMENT, LLC | $27.157.539 | 850.108 | 1,42% | Saham |
| Caligan Partners LP | $25.775.133 | 806.986 | 1,34% | Saham |
| Canaan Partners XI LLC | $23.955.000 | 750.000 | 1,25% | Saham |
| Siren, L.L.C. | $23.156.500 | 725.000 | 1,21% | Saham |
| Sio Capital Management, LLC | $22.208.361 | 695.315 | 1,16% | Saham |
| STEMPOINT CAPITAL LP | $20.210.163 | 632.754 | 1,05% | Saham |
| MARSHALL WACE, LLP | $18.625.268 | 583.133 | 0,97% | Saham |
| JENNISON ASSOCIATES LLC | $14.403.791 | 450.964 | 0,75% | Saham |
| TWO SIGMA INVESTMENTS, LP | $14.366.868 | 449.808 | 0,75% | Saham |
| GOLDMAN SACHS GROUP INC | $13.394.997 | 419.380 | 0,70% | Saham |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12.872.427 | 403.019 | 0,67% | Saham |
| Defilade Capital Management, L.P. | $12.037.228 | 376.870 | 0,63% | Saham |
| Walleye Capital LLC | $11.111.862 | 347.898 | 0,58% | Saham |
| Woodline Partners LP | $10.222.078 | 320.040 | 0,53% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9.086.930 | 284.500 | 0,47% | Opsi beli |
| BANK OF AMERICA CORP /DE/ | $8.955.529 | 280.386 | 0,47% | Saham |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $8.550.306 | 267.699 | 0,45% | Saham |
| Qube Research & Technologies Ltd | $8.525.872 | 266.934 | 0,44% | Saham |
| BNP PARIBAS FINANCIAL MARKETS | $7.672.850 | 240.227 | 0,40% | Saham |
| ALGERT GLOBAL LLC | $7.637.493 | 239.120 | 0,40% | Saham |
| VANGUARD FIDUCIARY TRUST CO | $7.180.272 | 224.805 | 0,37% | Saham |
| DIMENSIONAL FUND ADVISORS LP | $6.691.686 | 209.508 | 0,35% | Saham |
| Affinity Asset Advisors, LLC | $6.388.383 | 200.012 | 0,33% | Saham |
| FRANKLIN RESOURCES INC | $6.143.340 | 192.340 | 0,32% | Saham |
| HighVista Strategies LLC | $5.901.681 | 184.774 | 0,31% | Saham |
| MILLENNIUM MANAGEMENT LLC | $5.674.844 | 177.672 | 0,30% | Saham |
| CITADEL ADVISORS LLC | $5.581.036 | 174.735 | 0,29% | Saham |
| BOOTHBAY FUND MANAGEMENT, LLC | $5.543.474 | 173.559 | 0,29% | Saham |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5.174.280 | 162.000 | 0,27% | Saham |
| Jump Financial, LLC | $5.014.580 | 157.000 | 0,26% | Saham |
| VICTORY CAPITAL MANAGEMENT INC | $4.873.565 | 152.585 | 0,25% | Saham |
| Ensign Peak Advisors, Inc | $4.680.392 | 146.537 | 0,24% | Saham |
| Trexquant Investment LP | $4.239.716 | 132.740 | 0,22% | Saham |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3.931.495 | 123.090 | 0,21% | Saham |
| BARCLAYS PLC | $3.631.578 | 113.700 | 0,19% | Opsi beli |
| ORBIMED ADVISORS LLC | $3.257.880 | 102.000 | 0,17% | Saham |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2.849.208 | 89.205 | 0,15% | Saham |
| JANUS HENDERSON GROUP PLC | $2.711.816 | 70.814 | 0,14% | Saham |
| OPPENHEIMER & CO INC | $2.676.029 | 83.783 | 0,14% | Saham |
| XTX Topco Ltd | $2.597.361 | 81.320 | 0,14% | Saham |
| Kalehua Capital Management LLC | $2.378.412 | 74.465 | 0,12% | Saham |
| RAYMOND JAMES FINANCIAL INC | $2.177.094 | 68.162 | 0,11% | Saham |
| SEI INVESTMENTS CO | $2.127.428 | 66.607 | 0,11% | Saham |
| Squarepoint Ops LLC | $2.037.932 | 63.805 | 0,11% | Saham |
| Fisher Asset Management, LLC | $1.923.745 | 60.230 | 0,10% | Saham |
| ALPS ADVISORS INC | $1.921.478 | 60.159 | 0,10% | Saham |
| CITIGROUP INC | $1.921.383 | 60.156 | 0,10% | Saham |
| ALLIANCEBERNSTEIN L.P. | $1.854.486 | 48.420 | 0,10% | Saham |
| AXA Investment Managers S.A. | $1.801.758 | 128.789 | 0,09% | Saham |
| RHUMBLINE ADVISERS | $1.662.114 | 52.039 | 0,09% | Saham |
| TD Asset Management Inc | $1.597.000 | 50.000 | 0,08% | Saham |
| Arkadios Wealth Advisors | $1.575.792 | 49.336 | 0,08% | Saham |
| TWO SIGMA ADVISERS, LP | $1.548.481 | 58.900 | 0,08% | Saham |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.491.502 | 46.697 | 0,08% | Saham |
| JANE STREET GROUP, LLC | $1.437.300 | 45.000 | 0,08% | Opsi jual |
| Susquehanna Portfolio Strategies, LLC | $1.433.403 | 44.878 | 0,07% | Saham |
| Swiss National Bank | $1.427.718 | 44.700 | 0,07% | Saham |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.415.804 | 44.327 | 0,07% | Saham |
| ExodusPoint Capital Management, LP | $1.310.370 | 41.026 | 0,07% | Saham |
| Rafferty Asset Management, LLC | $1.236.142 | 38.702 | 0,06% | Saham |
| Bank of New York Mellon Corp | $1.224.612 | 38.341 | 0,06% | Saham |
| Verdad Advisers, LP | $1.149.936 | 36.003 | 0,06% | Saham |
| WELLS FARGO & COMPANY/MN | $1.071.938 | 33.561 | 0,06% | Saham |
| Sofinnova Investments, Inc. | $1.030.608 | 32.267 | 0,05% | Saham |
| Engineers Gate Manager LP | $1.020.739 | 31.958 | 0,05% | Saham |
| BlackRock, Inc. | $841.236 | 26.338 | 0,04% | Saham |
| PDT Partners, LLC | $820.347 | 25.684 | 0,04% | Saham |
| MILLENNIUM MANAGEMENT LLC | $798.500 | 25.000 | 0,04% | Opsi beli |
| STRS OHIO | $705.874 | 22.100 | 0,04% | Saham |
| MetLife Investment Management, LLC | $693.833 | 21.723 | 0,04% | Saham |
| LMR Partners LLP | $675.563 | 21.151 | 0,04% | Saham |
| Auour Investments LLC | $671.379 | 21.020 | 0,04% | Saham |
| Vanguard Global Advisers, LLC | $643.719 | 20.154 | 0,03% | Saham |
| Elmind Capital, LP | $638.800 | 20.000 | 0,03% | Saham |
| PROFUND ADVISORS LLC | $625.641 | 19.588 | 0,03% | Saham |
| WELLINGTON MANAGEMENT GROUP LLP | $594.467 | 18.612 | 0,03% | Saham |
| Cubist Systematic Strategies, LLC | $549.946 | 39.310 | 0,03% | Saham |
| AMERIPRISE FINANCIAL INC | $540.425 | 16.920 | 0,03% | Saham |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $538.764 | 16.868 | 0,03% | Saham |
| WINTON GROUP Ltd | $536.592 | 16.800 | 0,03% | Saham |
| VANGUARD ASSET MANAGEMENT, Ltd | $494.399 | 15.479 | 0,03% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $479.100 | 15.000 | 0,03% | Opsi jual |
| Invesco Ltd. | $463.897 | 14.524 | 0,02% | Saham |
| FOX RUN MANAGEMENT, L.L.C. | $461.533 | 14.450 | 0,02% | Saham |
| NEW YORK STATE COMMON RETIREMENT FUND | $412.761 | 12.923 | 0,02% | Saham |
Orang dalam perusahaan 24 orang dalam · 12 pejabat · 12 direktur
| Orang Dalam | Peran | Aktivitas terakhir | Saham dimiliki | Beli 12m | Jual 12m | Bersih 12m |
|---|---|---|---|---|---|---|
| Todd Harris | President and CEO | 5 Mei 2026 A | 1.437.631 | 0 | 0 | $0 |
| Alan Fuhrman | Chief Financial Officer | 5 Mei 2026 A | 36.164 | 0 | 0 | $0 |
| Esther Van Den Boom | Chief Financial Officer | 15 Sep. 2022 A | 121.897 | 0 | 0 | $0 |
| Bhavesh Ashar | Chief Operating Officer | 5 Mei 2026 A | 15.013 | 0 | 0 | $0 |
| Yuliya Rueb | Vice President, Finance (PAO) | 5 Mei 2026 A | 43.354 | 0 | 0 | $0 |
| Douglas J Warner | Chief Medical Officer | 5 Mei 2026 A | 25.000 | 0 | 0 | $0 |
| Daniel Bensen | Chief Discovery Officer | 12 Feb. 2026 S | 146.981 | 0 | 11 | $-4.811.405 |
| Hiroomi Tada | Chief Medical Officer | 15 Maret 2024 A | 86.435 | 0 | 0 | $0 |
| Patel Piyush R. | Chief Development Officer | 21 Feb. 2023 G | 73.794 | 0 | 0 | $0 |
| Robert L. Hudkins | Chief Technology Officer | 15 Sep. 2022 A | 273.576 | 0 | 0 | $0 |
| Ronald V. Swanson | Chief Scientific Officer | 6 Sep. 2022 A | 273.254 | 0 | 0 | $0 |
| Ali D. Fawaz | General Counsel and Secretary | 16 Mei 2022 A | — | 0 | 0 | $0 |
| Habib J Dable | Direktur | 16 April 2026 A | — | 0 | 0 | $0 |
| Gilla Kaplan | Direktur | 26 Maret 2026 M | 28.231 | 0 | 1 | $-528.486 |
| Robert J More | Direktur | 19 Des. 2025 S | 3.823.425 | 0 | 2 | $-5.249.138 |
| Stephen Michael Rothenberg | Direktur | 29 Mei 2025 A | — | 0 | 0 | $0 |
| Rehan Verjee | Direktur | 29 Mei 2025 A | — | 0 | 0 | $0 |
| Susan Moran | Direktur | 29 Mei 2025 A | — | 0 | 0 | $0 |
| Nina S Kjellson | Direktur | 5 Feb. 2025 S | 443.885 | 0 | 0 | $0 |
| Adele M. Gulfo | Direktur | 29 Jan. 2025 A | — | 0 | 0 | $0 |
| Siddarth Subramony | Direktur | 29 Mei 2024 A | — | 0 | 0 | $0 |
| Jake Simson | Direktur | 29 Mei 2024 A | — | 0 | 0 | $0 |
| Isan Chen | Direktur | 31 Mei 2023 A | 192.783 | 0 | 0 | $0 |
| Boxer Capital Management, LLC | — | 18 Okt. 2024 A | 4.448.359 | 0 | 0 | $0 |
Orang dalam dari pengajuan SEC Form 3/4/5; bersih = hanya P/S pasar terbuka
Aktivis & pemilik 5%+ 5 saham
Investor yang mengajukan Jadwal 13D SEC — kepemilikan manfaat di atas 5% dengan niat untuk memengaruhi penerbit (kepemilikan aktivis, kampanye dewan, M&A). Setiap baris menunjukkan status terbaru yang diketahui dari posisi pengaju tersebut.
| Pengaju | Diajukan | Kepemilikan | Status | Tujuan | Pengajuan |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×7 pengajuan | 6 Maret 2026 | 21,20% | Amandemen | — | SEC |
| MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC ×3 pengajuan | 6 Des. 2024 | — | Pengajuan awal | — | SEC |
| Boxer Asset Management Inc, Joe Lewis | 15 Okt. 2024 | — | Pengajuan awal | — | SEC |
| Boxer Capital, LLC, MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC, Siddarth Subramony ×4 pengajuan | 15 Okt. 2024 | — | Pengajuan awal | — | SEC |
| Alta Partners NextGen Fund II, L.P., Alta Partners NextGen Fund II Management, LLC, Peter Hudson, Daniel Janney, Robert More | 27 Sep. 2021 | — | Pengajuan awal | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Kepemilikan ETF Dimiliki oleh 42 ETF
Bobot mencerminkan kepemilikan ekuitas langsung (N-PORT) saja; dana berbasis leverage atau derivatif mungkin memiliki eksposur swap tambahan yang tidak ditampilkan.
| Dana | Bobot | Unit | Per tanggal | Sumber |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,15% | 55.509 NS | 31 Mei 2026 | N-PORT |
| BBC · ETFis Series Trust I | 1,14% | 12.196 NS | 30 April 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,30% | 15.780 NS | 31 Mei 2026 | N-PORT |
| ESSC · Strategy Shares | 0,25% | 1.876 NS | 30 April 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,25% | 37.514 NS | 30 April 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 81.594 SH | 8 Agu 2026 | Harian |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,11% | 3.239 SH | 8 Agu 2026 | Harian |
| IBB · iShares Trust | 0,09% | 325.051 SH | 8 Agu 2026 | Harian |
| BIB · ProShares Trust | 0,09% | 1.974 NS | 31 Mei 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,09% | 33.120 NS | 30 April 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,07% | 39.429 SH | 8 Agu 2026 | Harian |
| IWO · iShares Trust | 0,06% | 331.311 SH | 8 Agu 2026 | Harian |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,04% | 211.804 SH | 8 Agu 2026 | Harian |
| SMMV · iShares Trust | 0,04% | 4.107 SH | 8 Agu 2026 | Harian |
| IWM · iShares Trust | 0,03% | 933.036 SH | 8 Agu 2026 | Harian |
| RSSL · Global X Funds | 0,03% | 11.184 NS | 30 April 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 7.291 NS | 31 Mei 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 1.219 NS | 31 Mei 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,02% | 114.471 NS | 31 Mei 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,02% | 1.805 SH | 8 Agu 2026 | Harian |
| UWM · ProShares Trust | 0,01% | 954 NS | 31 Mei 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 340.900 SH | 8 Agu 2026 | Harian |
| VHT · VANGUARD WORLD FUND | 0,01% | 67.148 SH | 8 Agu 2026 | Harian |
| URTY · ProShares Trust | 0,01% | 967 NS | 31 Mei 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 6.122 NS | 30 April 2026 | N-PORT |
| ISCV · iShares Trust | 0,01% | 1.827 SH | 8 Agu 2026 | Harian |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 18.052 NS | 31 Mei 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 583 SH | 8 Agu 2026 | Harian |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 1.002 NS | 31 Mei 2026 | N-PORT |
| ISCG · iShares Trust | 0,00% | 1.509 SH | 8 Agu 2026 | Harian |
| WSML · iShares Trust | 0,00% | 955 SH | 8 Agu 2026 | Harian |
| HDG · ProShares Trust | 0,00% | 24 NS | 31 Mei 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 12.741 NS | 30 April 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 46.810 SH | 8 Agu 2026 | Harian |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 13.115 NS | 31 Mei 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 6.606 SH | 8 Agu 2026 | Harian |
| DCOR · Dimensional ETF Trust | 0,00% | 548 NS | 30 April 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 1.440 NS | 30 April 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 682 NS | 30 April 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 10 NS | 31 Mei 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1.135.472 SH | 8 Agu 2026 | Harian |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3.044 SH | 8 Agu 2026 | Harian |