TYRA Tyra Biosciences, Inc. - Common Stock
$26,42
Prezzo · Ago 18, 2026
Fondamentali al Ago 4, 2026
Intervallo 52 sett.
$10–$41
54% of range
Rating Analisti
BUY
22 analysts
Prezzo Obiettivo
$51
+92% upside
P/E (TTM)
-13.1
ROE
-42.7%
Margine di Profitto Netto
—
TYRA Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane
Prezzo
$26.42
Capitalizzazione di Mercato
$1.42B
P/E (TTM)
-13.1
EPS (TTM)
$-2.01
Ricavi (TTM)
—
Rendimento div.
—
ROE
-42.7%
D/E Debito/Patrimonio
—
Intervallo 52 sett.
$10 – $41
TYRA Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione
Configure
Performance decennale Andamento di ricavi, utile netto, margini e EPS
Ricavi e Utile Netto
—
EPS
$-2.01
2021-12-31
→
2025-12-31
Flusso di cassa libero
$-95M
2021-12-31
→
2025-12-31
Margini
—
Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?
Metrica
Tendenza 5 anni
TYRA
Mediana dei peer
P/E (TTM)
-13.1
—
P/B
5.5
2.7
Price / FCF (Prezzo / FCF)
-14.9
—
Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC
Metrica
Tendenza 5 anni
TYRA
Mediana dei peer
ROA
-37.1%
-43.1%
ROE
-42.7%
-49.0%
Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio
Metrica
Tendenza 5 anni
TYRA
Mediana dei peer
Current Ratio (Rapporto corrente)
14.7
9.0
Quick Ratio
4.3
—
Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y
Metrica
Tendenza 5 anni
TYRA
Mediana dei peer
Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti
Metrica
Tendenza 5 anni
TYRA
Mediana dei peer
TYRA Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo
COMPRA
22 analisti
- Acquisto forte 9 40,9%
- Compra 11 50,0%
- Mantieni 2 9,1%
- Vendi 0 0,0%
- Vendita forte 0 0,0%
Target Price a 12 Mesi
11 analisti · 2026-08-16
Mediana
$53.00
Media
$50.82
← Sotto tutti i target
$26.42
Basso
$39.00
Alto
$59.00
Target mediano
$53.00
+100,6%
Target medio
$50.82
+92,3%
Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili
Sorpresa media
0.00%
| Periodo | EPS Actual | EPS Stimato | Sorpresa |
|---|---|---|---|
| 30 Giugno 2026 | $-0.69 | $-0.66 | -0.03% |
| 31 Marzo 2026 | $-0.64 | $-0.60 | -0.04% |
| 31 Dicembre 2025 | $-0.57 | $-0.54 | -0.03% |
| 30 Settembre 2025 | $-0.50 | $-0.51 | 0.01% |
| 30 Giugno 2025 | $-0.47 | $-0.54 | 0.07% |
| 31 Marzo 2025 | $-0.47 | $-0.50 | 0.03% |
Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore
| Ticker | Capitalizzazione di Mercato | P/E | Rev YoY | Margine Netto | ROE | Margine lordo |
|---|---|---|---|---|---|---|
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| RXRX | $2.16B | -2.8 | 26.9% | -863.4% | -62.9% | — |
| FBRX | $353M | -5.8 | 106.6% | -2555.2% | -86.9% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| BCAX | $953M | -6.7 | — | — | -33.0% | — |
| XNCR | $1.10B | -12.3 | 13.7% | -73.2% | -14.0% | — |
| JBIO | $761M | -4.8 | — | — | -47.7% | — |
| TRAX | — | — | — | — | — | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario
Conto Economico 12
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $103M | $80M | $63M | $43M | $21M | $7M | |
| SG&A Expense | $30M | $24M | $17M | $16M | $6M | $2M | |
| Operating Expenses | $133M | $104M | $80M | $59M | $26M | $9M | |
| Operating Income | $-133M | $-104M | $-80M | $-59M | $-26M | $-9M | |
| Other Non-op | $13M | $18M | $11M | $4M | $-6.0K | $-39.0K | |
| Income Tax | $0 | $0 | $0 | $2.0K | $1.0K | $1.0K | |
| Net Income | $-120M | $-86M | $-69M | $-55M | $-26M | $-9M | |
| EPS (Basic) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| EPS (Diluted) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| Shares (Basic) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| Shares (Diluted) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| EBITDA | $-132M | $-104M | $-80M | $-59M | $-26M | · |
Stato Patrimoniale 19
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $77M | $92M | $58M | $251M | $302M | $15M | |
| Prepaid Expense | $9M | $6M | $8M | $6M | $2M | $57.0K | |
| Current Assets | $265M | $347M | $212M | $257M | $304M | $15M | |
| PP&E (Net) | $1M | $2M | $2M | $1M | $1M | $297.0K | |
| PP&E (Gross) | · | $3M | $2M | $2M | $1M | $340.0K | |
| Accum. Depreciation | · | $1M | $807.0K | $461.0K | $169.0K | $43.0K | |
| Other Non-current Assets | $9M | $7M | $5M | $4M | $312.0K | $21.0K | |
| Total Assets | $283M | $364M | $226M | $266M | $307M | $16M | |
| Accounts Payable | $1M | $590.0K | $5M | $1M | $599.0K | $664.0K | |
| Current Liabilities | $18M | $15M | $15M | $6M | $4M | $2M | |
| Capital Leases | $5M | $6M | $6M | $2M | $981.0K | $0 | |
| Other Non-current Liabilities | $0 | $3.0K | $46.0K | $169.0K | $367.0K | $140.0K | |
| Total Liabilities | $23M | $20M | $22M | $8M | $5M | $2M | |
| Common Stock | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $0 | |
| Retained Earnings | $-371M | $-251M | $-165M | $-96M | $-40M | $-14M | |
| AOCI | $393.0K | $770.0K | $381.0K | $0 | · | · | |
| Stockholders' Equity | $259M | $343M | $204M | $258M | $302M | $-14M | |
| Liabilities + Equity | $283M | $364M | $226M | $266M | $307M | $16M | |
| Shares Outstanding | 53,706,357 | 50,749,945 | 43,024,634 | 42,353,550 | 41,441,135 | 1,829,377 |
Flusso di cassa 9
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $546.0K | $519.0K | $357.0K | $296.0K | $140.0K | $47.0K | |
| Stock-based Comp | $28M | $23M | $14M | $11M | $3M | $439.0K | |
| Other Non-cash | $-4M | $-7M | $5M | $-6M | $-478.0K | · | |
| Operating Cash Flow | $-95M | $-70M | $-50M | $-50M | $-24M | $-8M | |
| CapEx | $141.0K | $664.0K | $770.0K | $559.0K | $661.0K | $312.0K | |
| Investing Cash Flow | $72M | $-98M | $-145M | $-559.0K | $-645.0K | $-312.0K | |
| Financing Cash Flow | $8M | $202M | $2M | $632.0K | $311M | $23M | |
| Net Change in Cash | $-15M | $34M | $-193M | $-50M | $287M | $15M | |
| Free Cash Flow | $-95M | $-70M | $-51M | $-51M | $-24M | · |
Redditività 2
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -37.1% | -29.3% | -28.1% | -19.3% | -16.3% | · | |
| ROE | -42.7% | -24.5% | -32.4% | -21.1% | -8.6% | · |
Liquidità e Solvibilità 2
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 | · | |
| Quick Ratio | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 | · |
Valutazione (TTM) 8
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-120M | $-86M | $-69M | $-55M | $-26M | · | |
| Market Cap | $1.41B | $705M | $596M | $322M | $583M | · | |
| P/E | -13.1 | -9.2 | -8.5 | -5.8 | -7.4 | · | |
| P/B | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Tangible Book | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Cash Flow | -14.8 | -10.1 | -11.9 | -6.4 | -24.6 | · | |
| P / FCF | -14.8 | -10.0 | -11.7 | -6.3 | -23.9 | · | |
| Earnings Yield | -7.6% | -10.9% | -11.7% | -17.4% | -13.6% | · |
Conto Economico 11
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $39M | $33M | $28M | $25M | $24M | $25M | $22M | $23M | $18M | $17M | $21M | $19M | $12M | $10M | $10M | $11M | |
| SG&A Expense | $10M | $9M | $8M | $7M | $7M | $7M | $8M | $6M | $6M | $5M | $5M | $5M | $4M | $4M | $10M | $173.0K | |
| Operating Expenses | $49M | $42M | $37M | $33M | $31M | $32M | $30M | $29M | $24M | $22M | $26M | $24M | $16M | $14M | $15M | $14M | |
| Operating Income | $-49M | $-42M | $-37M | $-33M | $-31M | $-32M | $-30M | $-29M | $-24M | $-22M | $-26M | $-24M | $-16M | $-14M | $-15M | $-14M | |
| Other Non-op | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $5M | $5M | $4M | $3M | $3M | $3M | $2M | $3M | $5.0K | |
| Net Income | $-46M | $-39M | $-34M | $-30M | $-28M | $-28M | $-26M | $-24M | $-19M | $-18M | $-23M | $-21M | $-13M | $-12M | $-13M | $-13M | |
| EPS (Basic) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| EPS (Diluted) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| Shares (Basic) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| Shares (Diluted) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| EBITDA | $-49M | $-42M | · | $-33M | $-31M | $-32M | · | $-29M | $-24M | $-22M | · | $-24M | $-16M | $-14M | · | $-14M |
Stato Patrimoniale 19
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $74M | $85M | $77M | $62M | $98M | $101M | $92M | $104M | $99M | $254M | $58M | $216M | $232M | $242M | $251M | $263M | |
| Prepaid Expense | $13M | $11M | $9M | $6M | $6M | $6M | $6M | $5M | $5M | $8M | $8M | $9M | $8M | $5M | $6M | $4M | |
| Current Assets | $367M | $395M | $265M | $281M | $302M | $325M | $347M | $366M | $379M | $391M | $212M | $225M | $241M | $247M | $257M | $267M | |
| PP&E (Net) | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | |
| PP&E (Gross) | · | · | · | · | · | $3M | · | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | · | · | · | · | · | $1M | · | $1M | $1M | $926.0K | $807.0K | $706.0K | $629.0K | $544.0K | $461.0K | $379.0K | |
| Other Non-current Assets | $9M | $10M | $9M | $13M | $11M | $10M | $7M | $6M | $5M | $5M | $5M | $5M | $866.0K | $4M | $4M | $4M | |
| Total Assets | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Accounts Payable | $2M | $4M | $1M | $2M | $2M | $2M | $590.0K | $1M | $2M | $3M | $5M | $2M | $1M | $1M | $1M | $3M | |
| Current Liabilities | $25M | $19M | $18M | $16M | $14M | $14M | $15M | $12M | $10M | $9M | $15M | $10M | $5M | $4M | $6M | $5M | |
| Capital Leases | $5M | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $2M | $2M | $3M | |
| Other Non-current Liabilities | · | · | $0 | $0 | $0 | $0 | $3.0K | $11.0K | $20.0K | $29.0K | $46.0K | $77.0K | $108.0K | $139.0K | $169.0K | $226.0K | |
| Total Liabilities | $30M | $24M | $23M | $21M | $19M | $20M | $20M | $18M | $16M | $15M | $22M | $16M | $11M | $6M | $8M | $8M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Retained Earnings | $-456M | $-411M | $-371M | $-337M | $-308M | $-279M | $-251M | $-226M | $-202M | $-183M | $-165M | $-142M | $-121M | $-108M | $-96M | $-83M | |
| AOCI | $-580.0K | $107.0K | $393.0K | $442.0K | $436.0K | $688.0K | $770.0K | $2M | $-184.0K | $-6.0K | $381.0K | · | · | · | $0 | · | |
| Stockholders' Equity | $354M | $388M | $259M | $281M | $302M | $324M | $343M | $362M | $376M | $390M | $204M | $222M | $239M | $249M | $258M | $268M | |
| Liabilities + Equity | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Shares Outstanding | 59,662,877 | 59,469,687 | 53,706,357 | 53,318,198 | 53,233,494 | 53,089,957 | 50,749,945 | 52,871,825 | 52,736,458 | 52,474,533 | 43,024,634 | 42,928,884 | 42,817,233 | 42,535,374 | 42,353,550 | 42,136,971 |
Flusso di cassa 11
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $138.0K | $138.0K | $132.0K | $131.0K | $140.0K | $143.0K | $144.0K | $127.0K | $126.0K | $122.0K | $102.0K | $86.0K | $89.0K | $83.0K | $82.0K | $82.0K | |
| Stock-based Comp | $10M | $8M | $8M | $8M | $6M | $6M | $7M | $8M | $4M | $4M | $4M | $4M | $3M | $2M | $3M | $1M | |
| Other Non-cash | · | $-1M | · | · | · | $-4M | · | · | · | $-8M | · | · | · | $-483.0K | · | · | |
| Operating Cash Flow | $-31M | $-33M | $-24M | $-22M | $-24M | $-25M | $-20M | $-18M | $-10M | $-22M | $-14M | $-17M | $-10M | $-10M | $-12M | $-12M | |
| CapEx | $66.0K | $88.0K | $57.0K | $39.0K | $31.0K | $14.0K | $6.0K | $52.0K | $470.0K | $136.0K | $603.0K | $83.0K | $43.0K | $41.0K | $21.0K | $48.0K | |
| Investing Cash Flow | $18M | $-120M | $34M | $-15M | $21M | $32M | $7M | $22M | $-145M | $18M | $-144M | $-83.0K | $-43.0K | $-41.0K | $-21.0K | $-48.0K | |
| Stock Issued | $0 | $148M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $148M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $160M | $5M | $647.0K | $583.0K | $2M | $706.0K | $743.0K | $373.0K | $200M | $324.0K | $467.0K | $370.0K | $376.0K | $3.0K | $364.0K | |
| Net Change in Cash | $-11M | $8M | $15M | $-37M | $-2M | $9M | $-12M | $4M | $-155M | $196M | $-158M | $-17M | $-9M | $-10M | $-12M | $-12M | |
| Free Cash Flow | · | $-33M | · | · | · | $-25M | · | · | · | $-22M | · | · | · | $-10M | · | · |
Redditività 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -12.9% | -10.4% | · | -8.8% | -7.9% | -7.5% | · | -7.8% | -5.8% | -5.5% | · | -8.2% | -4.9% | -4.3% | · | -4.2% | |
| ROE | -13.9% | -11.1% | · | -9.3% | -8.3% | -7.9% | · | -8.2% | -6.1% | -5.7% | · | -8.6% | -5.1% | -4.4% | · | -4.3% |
Liquidità e Solvibilità 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 20.5 | · | 17.7 | 21.9 | 22.8 | · | 29.5 | 36.5 | 44.8 | · | 22.1 | 44.5 | 67.0 | · | 48.7 | |
| Quick Ratio | 3.0 | 4.4 | · | 3.9 | 7.2 | 7.1 | · | 8.4 | 9.6 | 29.2 | · | 21.3 | 43.0 | 65.6 | · | 48.0 |
Valutazione (TTM) 8
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-143M | $-125M | · | $-110M | $-99M | $-89M | · | $-82M | $-71M | $-64M | · | $-59M | $-53M | $-54M | · | $-49M | |
| Market Cap | $1.91B | $2.28B | · | $746M | $509M | $494M | · | $1.24B | $843M | $861M | · | $591M | $729M | $684M | · | $370M | |
| P/E | -13.9 | -18.4 | · | -7.6 | -5.7 | -6.0 | · | -15.0 | -10.9 | -11.5 | · | -10.0 | -13.6 | -12.4 | · | -5.1 | |
| P/B | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Tangible Book | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Cash Flow | · | -69.9 | · | · | · | -19.4 | · | · | · | -39.1 | · | · | · | -69.4 | · | · | |
| P / FCF | · | -69.7 | · | · | · | -19.4 | · | · | · | -38.8 | · | · | · | -69.1 | · | · | |
| Earnings Yield | -7.2% | -5.4% | · | -13.2% | -17.4% | -16.7% | · | -6.7% | -9.2% | -8.7% | · | -10.0% | -7.3% | -8.1% | · | -19.8% |
Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni
Conto Economico
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Utile netto | $-120M | $-86M | $-69M | $-55M | $-26M |
| EPS Diluito | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 |
Stato Patrimoniale
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Rapporto corrente | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 |
| Quick Ratio | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 |
Flusso di cassa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flusso di cassa libero | $-95M | $-70M | $-51M | $-51M | $-24M |
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Proprietari istituzionali (13F) 182 filer · $1.9B totale · Aggiornato al 30 Giugno 2026
Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.
Attività istituzionale — Q2 2026 vs trimestre precedente
| Nuove posizioni | Posizioni chiuse | Aumentato | Diminuito | Variazione netta delle azioni |
|---|---|---|---|---|
| 41 (-9 vs trimestre precedente) | 22 (+9 vs trimestre precedente) | 60 (+8 vs trimestre precedente) | 49 (+12 vs trimestre precedente) | +7.7M |
Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.
| Istituzione | Valore | Azioni | % di 13F tracciati | Tipo |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $389.624.083 | 12.198.625 | 20,33% | Azioni |
| FMR LLC | $259.465.452 | 8.123.527 | 13,54% | Azioni |
| Alta Partners Management Company, L.P. | $122.120.195 | 3.823.425 | 6,37% | Azioni |
| Nextech Invest Ltd. | $113.501.505 | 3.553.585 | 5,92% | Azioni |
| TCG Crossover Management, LLC | $103.772.421 | 3.248.980 | 5,42% | Azioni |
| STATE STREET CORP | $68.363.354 | 2.140.368 | 3,57% | Azioni |
| Commodore Capital LP | $59.887.500 | 1.875.000 | 3,13% | Azioni |
| Paradigm Biocapital Advisors LP | $58.405.708 | 1.828.607 | 3,05% | Azioni |
| Nextech Invest Ltd. | $56.376.468 | 4.055.861 | 2,94% | Azioni |
| VANGUARD CAPITAL MANAGEMENT LLC | $48.179.797 | 1.508.447 | 2,51% | Azioni |
| BVF INC/IL | $47.149.700 | 1.476.196 | 2,46% | Azioni |
| VANGUARD GROUP INC | $36.938.081 | 1.405.024 | 1,93% | Azioni |
| 5AM Venture Management, LLC | $32.875.778 | 1.029.298 | 1,72% | Azioni |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $32.482.980 | 1.017.000 | 1,70% | Azioni |
| Hood River Capital Management LLC | $32.475.794 | 1.016.775 | 1,69% | Azioni |
| GEODE CAPITAL MANAGEMENT, LLC | $27.157.539 | 850.108 | 1,42% | Azioni |
| Caligan Partners LP | $25.775.133 | 806.986 | 1,34% | Azioni |
| Canaan Partners XI LLC | $23.955.000 | 750.000 | 1,25% | Azioni |
| Siren, L.L.C. | $23.156.500 | 725.000 | 1,21% | Azioni |
| Sio Capital Management, LLC | $22.208.361 | 695.315 | 1,16% | Azioni |
| STEMPOINT CAPITAL LP | $20.210.163 | 632.754 | 1,05% | Azioni |
| MARSHALL WACE, LLP | $18.625.268 | 583.133 | 0,97% | Azioni |
| JENNISON ASSOCIATES LLC | $14.403.791 | 450.964 | 0,75% | Azioni |
| TWO SIGMA INVESTMENTS, LP | $14.366.868 | 449.808 | 0,75% | Azioni |
| GOLDMAN SACHS GROUP INC | $13.394.997 | 419.380 | 0,70% | Azioni |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12.872.427 | 403.019 | 0,67% | Azioni |
| Defilade Capital Management, L.P. | $12.037.228 | 376.870 | 0,63% | Azioni |
| Walleye Capital LLC | $11.111.862 | 347.898 | 0,58% | Azioni |
| Woodline Partners LP | $10.222.078 | 320.040 | 0,53% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9.086.930 | 284.500 | 0,47% | Opzione Call |
| BANK OF AMERICA CORP /DE/ | $8.955.529 | 280.386 | 0,47% | Azioni |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $8.550.306 | 267.699 | 0,45% | Azioni |
| Qube Research & Technologies Ltd | $8.525.872 | 266.934 | 0,44% | Azioni |
| BNP PARIBAS FINANCIAL MARKETS | $7.672.850 | 240.227 | 0,40% | Azioni |
| ALGERT GLOBAL LLC | $7.637.493 | 239.120 | 0,40% | Azioni |
| VANGUARD FIDUCIARY TRUST CO | $7.180.272 | 224.805 | 0,37% | Azioni |
| DIMENSIONAL FUND ADVISORS LP | $6.691.686 | 209.508 | 0,35% | Azioni |
| Affinity Asset Advisors, LLC | $6.388.383 | 200.012 | 0,33% | Azioni |
| FRANKLIN RESOURCES INC | $6.143.340 | 192.340 | 0,32% | Azioni |
| HighVista Strategies LLC | $5.901.681 | 184.774 | 0,31% | Azioni |
| MILLENNIUM MANAGEMENT LLC | $5.674.844 | 177.672 | 0,30% | Azioni |
| CITADEL ADVISORS LLC | $5.581.036 | 174.735 | 0,29% | Azioni |
| BOOTHBAY FUND MANAGEMENT, LLC | $5.543.474 | 173.559 | 0,29% | Azioni |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5.174.280 | 162.000 | 0,27% | Azioni |
| Jump Financial, LLC | $5.014.580 | 157.000 | 0,26% | Azioni |
| VICTORY CAPITAL MANAGEMENT INC | $4.873.565 | 152.585 | 0,25% | Azioni |
| Ensign Peak Advisors, Inc | $4.680.392 | 146.537 | 0,24% | Azioni |
| Trexquant Investment LP | $4.239.716 | 132.740 | 0,22% | Azioni |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3.931.495 | 123.090 | 0,21% | Azioni |
| BARCLAYS PLC | $3.631.578 | 113.700 | 0,19% | Opzione Call |
| ORBIMED ADVISORS LLC | $3.257.880 | 102.000 | 0,17% | Azioni |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2.849.208 | 89.205 | 0,15% | Azioni |
| JANUS HENDERSON GROUP PLC | $2.711.816 | 70.814 | 0,14% | Azioni |
| OPPENHEIMER & CO INC | $2.676.029 | 83.783 | 0,14% | Azioni |
| XTX Topco Ltd | $2.597.361 | 81.320 | 0,14% | Azioni |
| Kalehua Capital Management LLC | $2.378.412 | 74.465 | 0,12% | Azioni |
| RAYMOND JAMES FINANCIAL INC | $2.177.094 | 68.162 | 0,11% | Azioni |
| SEI INVESTMENTS CO | $2.127.428 | 66.607 | 0,11% | Azioni |
| Squarepoint Ops LLC | $2.037.932 | 63.805 | 0,11% | Azioni |
| Fisher Asset Management, LLC | $1.923.745 | 60.230 | 0,10% | Azioni |
| ALPS ADVISORS INC | $1.921.478 | 60.159 | 0,10% | Azioni |
| CITIGROUP INC | $1.921.383 | 60.156 | 0,10% | Azioni |
| ALLIANCEBERNSTEIN L.P. | $1.854.486 | 48.420 | 0,10% | Azioni |
| AXA Investment Managers S.A. | $1.801.758 | 128.789 | 0,09% | Azioni |
| RHUMBLINE ADVISERS | $1.662.114 | 52.039 | 0,09% | Azioni |
| TD Asset Management Inc | $1.597.000 | 50.000 | 0,08% | Azioni |
| Arkadios Wealth Advisors | $1.575.792 | 49.336 | 0,08% | Azioni |
| TWO SIGMA ADVISERS, LP | $1.548.481 | 58.900 | 0,08% | Azioni |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.491.502 | 46.697 | 0,08% | Azioni |
| JANE STREET GROUP, LLC | $1.437.300 | 45.000 | 0,08% | Opzione Put |
| Susquehanna Portfolio Strategies, LLC | $1.433.403 | 44.878 | 0,07% | Azioni |
| Swiss National Bank | $1.427.718 | 44.700 | 0,07% | Azioni |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.415.804 | 44.327 | 0,07% | Azioni |
| ExodusPoint Capital Management, LP | $1.310.370 | 41.026 | 0,07% | Azioni |
| Rafferty Asset Management, LLC | $1.236.142 | 38.702 | 0,06% | Azioni |
| Bank of New York Mellon Corp | $1.224.612 | 38.341 | 0,06% | Azioni |
| Verdad Advisers, LP | $1.149.936 | 36.003 | 0,06% | Azioni |
| WELLS FARGO & COMPANY/MN | $1.071.938 | 33.561 | 0,06% | Azioni |
| Sofinnova Investments, Inc. | $1.030.608 | 32.267 | 0,05% | Azioni |
| Engineers Gate Manager LP | $1.020.739 | 31.958 | 0,05% | Azioni |
| BlackRock, Inc. | $841.236 | 26.338 | 0,04% | Azioni |
| PDT Partners, LLC | $820.347 | 25.684 | 0,04% | Azioni |
| MILLENNIUM MANAGEMENT LLC | $798.500 | 25.000 | 0,04% | Opzione Call |
| STRS OHIO | $705.874 | 22.100 | 0,04% | Azioni |
| MetLife Investment Management, LLC | $693.833 | 21.723 | 0,04% | Azioni |
| LMR Partners LLP | $675.563 | 21.151 | 0,04% | Azioni |
| Auour Investments LLC | $671.379 | 21.020 | 0,04% | Azioni |
| Vanguard Global Advisers, LLC | $643.719 | 20.154 | 0,03% | Azioni |
| Elmind Capital, LP | $638.800 | 20.000 | 0,03% | Azioni |
| PROFUND ADVISORS LLC | $625.641 | 19.588 | 0,03% | Azioni |
| WELLINGTON MANAGEMENT GROUP LLP | $594.467 | 18.612 | 0,03% | Azioni |
| Cubist Systematic Strategies, LLC | $549.946 | 39.310 | 0,03% | Azioni |
| AMERIPRISE FINANCIAL INC | $540.425 | 16.920 | 0,03% | Azioni |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $538.764 | 16.868 | 0,03% | Azioni |
| WINTON GROUP Ltd | $536.592 | 16.800 | 0,03% | Azioni |
| VANGUARD ASSET MANAGEMENT, Ltd | $494.399 | 15.479 | 0,03% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $479.100 | 15.000 | 0,03% | Opzione Put |
| Invesco Ltd. | $463.897 | 14.524 | 0,02% | Azioni |
| FOX RUN MANAGEMENT, L.L.C. | $461.533 | 14.450 | 0,02% | Azioni |
| NEW YORK STATE COMMON RETIREMENT FUND | $412.761 | 12.923 | 0,02% | Azioni |
Insider aziendali 24 insider · 12 dirigenti · 12 direttori
| Insider | Ruolo | Ultima attività | Azioni possedute | Acquisti 12m | Vendite 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Todd Harris | President and CEO | 05 Maggio 2026 A | 1.437.631 | 0 | 0 | $0 |
| Alan Fuhrman | Chief Financial Officer | 05 Maggio 2026 A | 36.164 | 0 | 0 | $0 |
| Esther Van Den Boom | Chief Financial Officer | 15 Settembre 2022 A | 121.897 | 0 | 0 | $0 |
| Bhavesh Ashar | Chief Operating Officer | 05 Maggio 2026 A | 15.013 | 0 | 0 | $0 |
| Yuliya Rueb | Vice President, Finance (PAO) | 05 Maggio 2026 A | 43.354 | 0 | 0 | $0 |
| Douglas J Warner | Chief Medical Officer | 05 Maggio 2026 A | 25.000 | 0 | 0 | $0 |
| Daniel Bensen | Chief Discovery Officer | 12 Febbraio 2026 S | 146.981 | 0 | 11 | $-4.811.405 |
| Hiroomi Tada | Chief Medical Officer | 15 Marzo 2024 A | 86.435 | 0 | 0 | $0 |
| Patel Piyush R. | Chief Development Officer | 21 Febbraio 2023 G | 73.794 | 0 | 0 | $0 |
| Robert L. Hudkins | Chief Technology Officer | 15 Settembre 2022 A | 273.576 | 0 | 0 | $0 |
| Ronald V. Swanson | Chief Scientific Officer | 06 Settembre 2022 A | 273.254 | 0 | 0 | $0 |
| Ali D. Fawaz | General Counsel and Secretary | 16 Maggio 2022 A | — | 0 | 0 | $0 |
| Habib J Dable | Direttore | 16 Aprile 2026 A | — | 0 | 0 | $0 |
| Gilla Kaplan | Direttore | 26 Marzo 2026 M | 28.231 | 0 | 1 | $-528.486 |
| Robert J More | Direttore | 19 Dicembre 2025 S | 3.823.425 | 0 | 2 | $-5.249.138 |
| Stephen Michael Rothenberg | Direttore | 29 Maggio 2025 A | — | 0 | 0 | $0 |
| Rehan Verjee | Direttore | 29 Maggio 2025 A | — | 0 | 0 | $0 |
| Susan Moran | Direttore | 29 Maggio 2025 A | — | 0 | 0 | $0 |
| Nina S Kjellson | Direttore | 05 Febbraio 2025 S | 443.885 | 0 | 0 | $0 |
| Adele M. Gulfo | Direttore | 29 Gennaio 2025 A | — | 0 | 0 | $0 |
| Siddarth Subramony | Direttore | 29 Maggio 2024 A | — | 0 | 0 | $0 |
| Jake Simson | Direttore | 29 Maggio 2024 A | — | 0 | 0 | $0 |
| Isan Chen | Direttore | 31 Maggio 2023 A | 192.783 | 0 | 0 | $0 |
| Boxer Capital Management, LLC | — | 18 Ottobre 2024 A | 4.448.359 | 0 | 0 | $0 |
Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato
Attivisti e proprietari del 5%+ 5 partecipazioni
Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.
| Depositante | Depositato | Partecipazione | Stato | Scopo | Deposito |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×7 depositi | 06 Marzo 2026 | 21,20% | Modifica | — | SEC |
| MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC ×3 depositi | 06 Dicembre 2024 | — | Deposito iniziale | — | SEC |
| Boxer Asset Management Inc, Joe Lewis | 15 Ottobre 2024 | — | Deposito iniziale | — | SEC |
| Boxer Capital, LLC, MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC, Siddarth Subramony ×4 depositi | 15 Ottobre 2024 | — | Deposito iniziale | — | SEC |
| Alta Partners NextGen Fund II, L.P., Alta Partners NextGen Fund II Management, LLC, Peter Hudson, Daniel Janney, Robert More | 27 Settembre 2021 | — | Deposito iniziale | Investimento passivo | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Proprietà ETF Posseduti da 42 ETF
Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.
| Fondo | Peso | Unità | Aggiornato al | Fonte |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,15% | 55.509 NS | 31 Maggio 2026 | N-PORT |
| BBC · ETFis Series Trust I | 1,14% | 12.196 NS | 30 Aprile 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,30% | 15.780 NS | 31 Maggio 2026 | N-PORT |
| ESSC · Strategy Shares | 0,25% | 1.876 NS | 30 Aprile 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,25% | 37.514 NS | 30 Aprile 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 81.594 SH | 08 Agosto 2026 | Giornaliero |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,11% | 3.239 SH | 08 Agosto 2026 | Giornaliero |
| IBB · iShares Trust | 0,09% | 325.051 SH | 08 Agosto 2026 | Giornaliero |
| BIB · ProShares Trust | 0,09% | 1.974 NS | 31 Maggio 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,09% | 33.120 NS | 30 Aprile 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,07% | 39.429 SH | 08 Agosto 2026 | Giornaliero |
| IWO · iShares Trust | 0,06% | 331.311 SH | 08 Agosto 2026 | Giornaliero |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,04% | 211.804 SH | 08 Agosto 2026 | Giornaliero |
| SMMV · iShares Trust | 0,04% | 4.107 SH | 08 Agosto 2026 | Giornaliero |
| IWM · iShares Trust | 0,03% | 933.036 SH | 08 Agosto 2026 | Giornaliero |
| RSSL · Global X Funds | 0,03% | 11.184 NS | 30 Aprile 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 7.291 NS | 31 Maggio 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 1.219 NS | 31 Maggio 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,02% | 114.471 NS | 31 Maggio 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,02% | 1.805 SH | 08 Agosto 2026 | Giornaliero |
| UWM · ProShares Trust | 0,01% | 954 NS | 31 Maggio 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 340.900 SH | 08 Agosto 2026 | Giornaliero |
| VHT · VANGUARD WORLD FUND | 0,01% | 67.148 SH | 08 Agosto 2026 | Giornaliero |
| URTY · ProShares Trust | 0,01% | 967 NS | 31 Maggio 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 6.122 NS | 30 Aprile 2026 | N-PORT |
| ISCV · iShares Trust | 0,01% | 1.827 SH | 08 Agosto 2026 | Giornaliero |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 18.052 NS | 31 Maggio 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 583 SH | 08 Agosto 2026 | Giornaliero |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 1.002 NS | 31 Maggio 2026 | N-PORT |
| ISCG · iShares Trust | 0,00% | 1.509 SH | 08 Agosto 2026 | Giornaliero |
| WSML · iShares Trust | 0,00% | 955 SH | 08 Agosto 2026 | Giornaliero |
| HDG · ProShares Trust | 0,00% | 24 NS | 31 Maggio 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 12.741 NS | 30 Aprile 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 46.810 SH | 08 Agosto 2026 | Giornaliero |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 13.115 NS | 31 Maggio 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 6.606 SH | 08 Agosto 2026 | Giornaliero |
| DCOR · Dimensional ETF Trust | 0,00% | 548 NS | 30 Aprile 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 1.440 NS | 30 Aprile 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 682 NS | 30 Aprile 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 10 NS | 31 Maggio 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1.135.472 SH | 08 Agosto 2026 | Giornaliero |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3.044 SH | 08 Agosto 2026 | Giornaliero |