AMRN Amarin Corporation plc - American Depositary Shares

NASDAQ · Biotechnology · 在 SEC EDGAR 上查看 ↗
$14.37
价格 · 八月 19, 2026
截至...的财报数据 七月 29, 2026

关于 Amarin Corporation plc - American Depositary Shares 公司概况(来自维基百科)

Amarin Corporation is an Irish-American biopharmaceutical company founded in 1993 and headquartered in Dublin, Ireland and Bridgewater, New Jersey. The company develops and markets medicines for the treatment of cardiovascular disease. It has developed the drug Vascepa (AMR-101), a prescription grade omega-3 fatty acid.

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Amarin Corporation is an Irish-American biopharmaceutical company founded in 1993 and headquartered in Dublin, Ireland and Bridgewater, New Jersey. The company develops and markets medicines for the treatment of cardiovascular disease. It has developed the drug Vascepa (AMR-101), a prescription grade omega-3 fatty acid.

In July 2012, their lead-candidate drug named Vascepa (AMR-101) received FDA-approval, competing against GlaxoSmithKline's Lovaza.

History

Amarin Corporation plc (formerly Ethical Holdings plc) was originally incorporated in England as a private limited company on March 1, 1989, and later re-registered as a public company on March 19, 1993. In 2002, the company suffered losses worth $37 million; 2003 losses exceeded $19 million. As of 2005, it was developing neurology drugs. It developed Miraxion to treat serious hereditary neurodegenerative disease.

In December 2007, Amarin acquired Ester Neurosciences Limited for US$8.1 million. In 2011, CEO Joe Zakrzewski said that the company would like to first work on building its infrastructure out to commercialize the drug in the United States.

Products and development

Vascepa (USA) / Vazkepa (EU)

Amarin´s sole product VASCEPA® came on the market in 2013 for triglyceride levels >=500 milligrams per deciliter. In December 2019, the FDA approved "...the use of Vascepa (icosapent ethyl) as an adjunctive (secondary) therapy to reduce the risk of cardiovascular events among adults with elevated triglyceride levels (a type of fat in the blood) of 150 milligrams per deciliter or higher. Patients must also have either established cardiovascular disease or diabetes and two or more additional risk factors for cardiovascular disease....Vascepa is the first FDA approved drug to reduce cardiovascular risk among patients with elevated triglyceride levels as an add-on to maximally tolerated statin therapy.

Furthermore, VASCEPA® is in use in clinical trials by 3rd parties to see, if it has an effect on Alzheimer, Colon Cancer, Nonalcoholic Steatohepatitis (NASH), and other diseases.

HLS Therapeutics, Amarin´s license partner in Canada, presented results of their COVID-19 clinical trial for Vascepa at National Lipid Association Scientific Sessions 2020, December 12. The results demonstrated a 25% reduction of hs-CRP, a biomarker for inflammation. Most people with COVID-19 die, because of a cytokine storm, which causes an uncontrolled and excessive release of pro-inflammatory signaling molecules called cytokines. Two more COVID-19 studies are actually running with Vascepa to validate and proof further benefits.

On January 28, the Committee for Medicinal Products for Human Use gave a positive recommendation for Vazcepa (its name in the EU), which the European Commission finally approved on March 30.

Patent disputes

On March 30, 2020, the designated patent judge in the U.S. District Court for the District of Nevada, Miranda Du, ruled for generic-drug makers Hikma Pharmaceuticals and Dr. Reddy's Laboratories in a lawsuit with Amarin over patents on Amarin's drug, Vascepa. Soon after, on April 2, 2020, Amarin filed an appeal of the ruling. The appeal was lost and an en-banc was also not granted, afterwards. On November 30, three weeks after Hikma Pharmaceuticals started the distribution of their generic version of Vascepa, Amarin filed a complaint of patent infringement against Hikma. On February 11, 2021, Amarin filed a petition for certiorari with the US Supreme Court. On June 21, 2021, the petition was denied.

== Finance ==

来源:维基百科 (英语), CC BY-SA 4.0 · 在维基百科上查看 ↗

Wikidata ↗

AMRN 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围

价格
$14.37
市值
$5.98B
P/E (TTM)
-159.7
每股收益 (TTM)
$-0.09
营收 (TTM)
$214M
股息收益率
ROE
-8.4%
负债/权益
52周区间
$13 – $21

AMRN 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图

10年表现 收入、净利润、利润率和每股收益趋势

营收与净利润 $214M
10-point trend, +64.2%
2016-12-31 2025-12-31
EPS $-0.09
10-point trend, +78.0%
2016-12-31 2025-12-31
自由现金流
4-point trend, +69.4%
2016-12-31 2020-12-31
利润率 -18.2%
7-point trend, -23.1%
2016-12-31 2025-12-31

估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜?

指标
5年趋势
AMRN
同行中位数
P/E (TTM)
5-point trend, -104.6%
-159.7
55.9
P/S (TTM) (市销率 (TTM))
5-point trend, -93.0%
28.0
5.5
P/B (市净率)
5-point trend, -97.8%
13.0
1.8

盈利能力 毛利率、营业利润率和净利率;股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)

指标
5年趋势
AMRN
同行中位数
Gross Margin (毛利率)
5-point trend, -25.8%
56.6%
63.8%
Operating Margin (营业利润率)
5-point trend, +50.3%
-23.5%
Net Profit Margin (净利润率)
5-point trend, +64.3%
-18.2%
-14.2%
ROA
5-point trend, +86.6%
-5.7%
-4.2%
ROE
5-point trend, +96.4%
-8.4%
-6.0%
ROIC
5-point trend, +74.7%
-11.8%

财务健康 债务、流动性、偿付能力 — 资产负债表强度

指标
5年趋势
AMRN
同行中位数
Current Ratio (流动比率)
5-point trend, +39.0%
3.3
3.7
Quick Ratio (速动比率)
5-point trend, +10.0%
2.2

成长 营收、每股收益 (EPS) 和净利润增长:同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)

指标
5年趋势
AMRN
同行中位数
Revenue YoY (营收同比增长)
5-point trend, -63.4%
-6.6%
Revenue CAGR 3Y (营收3年复合年增长率)
5-point trend, -63.4%
-16.7%
Revenue CAGR 5Y (营收5年复合年增长率)
5-point trend, -63.4%
-19.0%

每股指标 每股收益 (EPS)、每股净资产、每股现金流、每股股息

指标
5年趋势
AMRN
同行中位数
EPS (Diluted) (EPS (稀释))
5-point trend, -550.0%
$-0.09

资本效率 资产周转率、库存周转率、应收账款周转率

指标
5年趋势
AMRN
同行中位数

AMRN 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间

卖出 6 位分析师
  • 强烈买入 0 0.0%
  • 买入 0 0.0%
  • 持有 2 33.3%
  • 卖出 2 33.3%
  • 强烈卖出 2 33.3%

12个月价格目标

1 位分析师 · 2026-08-15
中位数目标 $12.00 -16.5%
平均目标 $12.00 -16.5%

收益历史 每股收益实际值 vs 预估值,惊喜%,达标率,下次财报日期

平均惊喜
0.20%
期间 EPS Actual EPS 预期 惊喜
2026年6月30日 $0.04 $-0.01 0.05%
2026年3月31日 $-0.09 $0.09 -0.18%
2025年12月31日 $0.01 $0.00 0.01%
2025年9月30日 $0.08 $-0.58 0.66%
2025年6月30日 $0.66 $-0.18 0.84%
2025年3月31日 $-0.76 $-0.58 -0.18%

同行比较(GICS 子行业) 关键指标与行业同行对比

股票代码 市值 P/E 营收同比增长 净利润率 ROE 毛利率
AMRN $5.81B -155.1 -6.6% -18.2% -8.4% 56.6%
ALKS $4.63B 19.6 -5.2% 16.4% 14.0%
PRTA $514M -2.1 -92.8% -2520.6% -63.6%

完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表

损益表 18
AMRN 的年度损益表数据
指标 趋势 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +294.2% $214M $229M $307M $369M $583M $614M $430M $229M $181M $130M $82M $54M
Cost of Revenue 8-point trend, +492.3% · · · · $121M $131M $96M $55M $45M $34M $28M $20M
Gross Profit 12-point trend, +258.5% $121M $81M $166M $242M $462M $483M $334M $175M $136M $96M $54M $34M
R&D Expense 12-point trend, -60.6% $20M $21M $22M $30M $29M $39M $34M $56M $47M $50M $51M $50M
SG&A Expense 12-point trend, +44.9% $115M $152M $200M $304M $408M $463M $324M $227M $135M $111M $101M $79M
Operating Expenses 12-point trend, +31.9% $171M $173M $233M $348M $451M $502M $358M $283M $182M $161M $152M $130M
Operating Income 12-point trend, +47.7% $-50M $-92M $-68M $-106M $11M $-20M $-24M $-108M $-46M $-66M $-98M $-96M
Interest Expense 12-point trend, -100.0% $7.0K $7.0K $8.0K $15.0K $129.0K $3M $7M $9M $10M $19M $20M $19M
Interest Income 12-point trend, +11205.2% $11M $13M $12M $3M $1M $5M $8M $1M $429.0K $234.0K $132.0K $96.0K
Other Non-op 12-point trend, -12.1% $3M $1M $2M $-740.0K $-302.0K $104.0K $-75.0K $-326.0K $74.0K $-482.0K $-228.0K $4M
Pretax Income 12-point trend, +39.1% $-36M $-77M $-54M $-104M $11M $-17M $-22M $-116M $-55M $-76M $-118M $-59M
Income Tax 12-point trend, +196.9% $3M $5M $5M $2M $4M $745.0K $164.0K $96.0K $13M $10M $-3M $-3M
Net Income 12-point trend, +31.2% $-39M $-82M $-59M $-106M $8M $-18M $-23M $-116M $-68M $-86M $-115M $-56M
EPS (Basic) 12-point trend, +71.9% $-0.09 $-0.20 $-0.15 $-0.26 $0.02 $-0.05 $-0.07 $-0.39 $-0.25 $-0.41 $-0.83 $-0.32
EPS (Diluted) 12-point trend, +75.0% $-0.09 $-0.20 $-0.15 $-0.26 $0.02 $-0.05 $-0.07 $-0.39 $-0.25 $-0.41 $-0.83 $-0.36
Shares (Basic) 12-point trend, +138.9% 414,984,000 410,937,000 407,655,000 401,155,000 395,992,000 381,759,000 342,538,000 297,237,000 270,652,000 211,874,000 180,654,000 173,719,000
Shares (Diluted) 12-point trend, +138.7% 414,984,000 410,937,000 407,655,000 401,155,000 402,480,000 381,759,000 342,538,000 297,237,000 270,652,000 211,874,000 180,654,000 173,824,000
EBITDA 9-point trend, +47.7% $-50M $-92M $-68M · · $-20M · $-108M $-46M $-66M $-98M $-96M
资产负债表 27
AMRN 的年度资产负债表数据
指标 趋势 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +12.6% $135M $121M $199M $218M $219M $187M $645M $249M $74M $98M $107M $120M
Short-term Investments 6-point trend, -46.5% $168M $173M $121M $92M $235M $314M · · · · · ·
Receivables 12-point trend, +1517.3% $127M $122M $134M $131M $164M $155M $116M $67M $45M $20M $14M $8M
Inventory 12-point trend, +1326.6% $196M $166M $259M $229M $235M $189M $77M $58M $30M $21M $19M $14M
Prepaid Expense 12-point trend, +824.8% $24M $13M $12M $19M $22M $31M $13M $3M $3M $7M $3M $3M
Other Current Assets · · · · · · · · · · · $3M
Current Assets 12-point trend, +347.3% $650M $595M $725M $689M $879M $879M $855M $378M $153M $146M $144M $145M
PP&E (Net) 12-point trend, -96.9% $12.0K $16.0K $114.0K $874.0K $1M $2M $2M $63.0K $28.0K $78.0K $243.0K $381.0K
PP&E (Gross) 12-point trend, +53.4% $1M $1M $1M $3M $3M $4M $3M $902.0K $844.0K $821.0K $997.0K $969.0K
Accum. Depreciation 12-point trend, +150.7% $1M $1M $1M $2M $2M $2M $1M $839.0K $816.0K $755.0K $754.0K $588.0K
Intangibles 12-point trend, +32.8% $13M $16M $19M $22M $24M $14M $15M $7M $8M $9M $9M $10M
Other Non-current Assets 12-point trend, -62.2% $1M $1M $1M $458.0K $456.0K $432.0K $1M $174.0K $174.0K $741.0K $174.0K $3M
Total Assets 12-point trend, +292.0% $671M $685M $832M $886M $1.07B $966M $882M $386M $162M $167M $173M $171M
Accounts Payable 12-point trend, +432.0% $45M $40M $53M $65M $115M $106M $50M $38M $25M $6M $11M $9M
Current Liabilities 12-point trend, +382.5% $194M $180M $259M $259M $371M $307M $242M $157M $109M $76M $51M $40M
Capital Leases 7-point trend, -35.6% $6M $8M $9M $10M $9M $9M $9M · · · · ·
Other Non-current Liabilities 12-point trend, +2738.1% $11M $12M $9M $8M $8M $6M $4M $11M $1M $710.0K $335.0K $386.0K
Total Liabilities 12-point trend, -18.5% $211M $199M $280M $291M $401M $339M $274M $233M $227M $176M $301M $260M
Long-term Debt 6-point trend, -52.7% · · · · · · $50M $80M $92M $94M $92M $105M
Total Debt 6-point trend, -100.0% · · · · · $0 · $80M $93M $101M $106M $105M
Common Stock 12-point trend, +116.7% $310M $305M $303M $299M $294M $290M $269M $247M $209M $207M $150M $143M
Paid-in Capital 9-point trend, +96.7% $1.92B $1.91B $1.90B $1.89B $1.86B $1.82B $1.76B $1.28B $978M · · ·
Retained Earnings 12-point trend, -76.0% $-1.71B $-1.67B $-1.59B $-1.53B $-1.42B $-1.43B $-1.41B $-1.39B $-1.27B $-1.20B $-1.12B $-970M
Treasury Stock 12-point trend, +30941.5% $67M $65M $64M $62M $61M $51M $36M $10M $4M $1M $411.0K $217.0K
Stockholders' Equity 12-point trend, +619.3% $459M $486M $552M $595M $667M $628M $608M $152M $-65M $-9M $-129M $-88M
Liabilities + Equity 12-point trend, +292.0% $671M $685M $832M $886M $1.07B $966M $882M $386M $162M $167M $173M $171M
Shares Outstanding 12-point trend, +138.4% 416,214,102 411,584,851 408,824,093 408,824,093 396,598,008 392,538,081 360,103,901 325,850,013 271,022,011 269,363,696 183,403,263 174,590,372
现金流 17
AMRN 的年度现金流数据
指标 趋势 202520242023202220212020201920182017201620152014
D&A 5-point trend, -88.4% · · · · · · · $23.0K $62.0K $138.0K $166.0K $198.0K
Stock-based Comp 12-point trend, +54.5% $14M $18M $16M $26M $37M $46M $31M $19M $14M $14M $14M $9M
Deferred Tax 4-point trend, +406.6% · · · · · · · · $11M $9M $-4M $-4M
Amort. of Intangibles 12-point trend, +368.1% $3M $3M $3M $3M $2M $1M $679.0K $646.0K $646.0K $645.0K $646.0K $646.0K
Restructuring 5-point trend, +164.1% $36M $0 $11M $14M $14M · · · · · · ·
Operating Cash Flow 12-point trend, +109.0% $7M $-31M $7M $-180M $-67M $-22M $-9M $-95M $-33M $-72M $-84M $-75M
CapEx 6-point trend, +800.0% · · · · · $252.0K $2M $58.0K $12.0K $21.0K $28.0K ·
Investing Cash Flow 10-point trend, +42142.9% $9M $-46M $-26M $175M $104M $-377M $-2M $-58.0K $-12.0K $-21.0K · ·
Net Debt Issued 3-point trend, -1415.2% · · · · · $-50M · $-15M $-3M · · ·
Stock Issued 3-point trend, +581.1% · · · · · · $440M $265M · $65M · ·
Stock Repurchased · · · · · · · · · · $194.0K ·
Net Stock Activity 3-point trend, +136615.5% · · · · · · · $265M · $65M $-194.0K ·
Financing Cash Flow 10-point trend, -103.2% $-2M $-1M $230.0K $-379.0K $-5M $-59M $410M $271M $8M $63M · ·
Net Change in Cash 12-point trend, +118.8% $14M $-78M $-18M $-5M $32M $-458M $398M $176M $-25M $-9M $-13M $-72M
Taxes Paid 7-point trend, +1592.5% $1M $4M $2M $-2M $4M $-207.0K $-67.0K · · · · ·
Free Cash Flow 5-point trend, +74.1% · · · · · $-22M · $-95M $-33M $-72M $-85M ·
Levered FCF 5-point trend, +76.3% · · · · · $-25M · $-104M $-45M $-93M $-104M ·
盈利能力 8
AMRN 的年度盈利能力数据
指标 趋势 202520242023202220212020201920182017201620152014
Gross Margin 9-point trend, -9.1% 56.6% 35.6% 53.9% · · 78.6% · 76.2% 75.2% 73.6% 65.9% 62.2%
Operating Margin 9-point trend, +86.7% -23.5% -40.2% -22.0% · · -3.2% · -47.2% -25.1% -50.4% -120.1% -177.0%
Net Margin 9-point trend, +82.5% -18.2% -35.9% -19.3% · · -2.9% · -50.8% -37.5% -66.4% -140.9% -104.0%
Pretax Margin 9-point trend, +84.6% -16.9% -33.8% -17.5% · · -2.8% · -50.8% -30.3% -58.7% -144.7% -109.2%
EBITDA Margin 9-point trend, +86.7% -23.5% -40.2% -22.0% · · -3.2% · -47.2% -25.1% -50.4% -120.1% -177.0%
ROA 9-point trend, +78.5% -5.7% -10.8% -6.9% · · -1.9% · -42.5% -41.3% -50.8% -66.9% -26.6%
ROE 9-point trend, -109.1% -8.4% -16.2% -10.7% · · -2.9% · -234.1% 183.0% 124.9% 105.9% 92.2%
ROIC 9-point trend, +97.9% -11.8% -20.1% -13.5% · · -3.3% · -46.6% -200.8% -80.6% 417.0% -551.6%
流动性与偿付能力 5
AMRN 的年度流动性与偿付能力数据
指标 趋势 202520242023202220212020201920182017201620152014
Current Ratio 9-point trend, -7.3% 3.3 3.3 2.8 · · 2.9 · 2.4 1.4 1.9 2.8 3.6
Quick Ratio 9-point trend, -30.1% 2.2 2.3 1.8 · · 2.1 · 2.0 1.1 1.6 2.4 3.2
Debt / Equity 6-point trend, +100.0% · · · · · 0.0 · 0.5 -1.4 -11.2 -0.8 -1.2
LT Debt / Equity 5-point trend, +129.9% · · · · · · · 0.3 -1.1 -9.4 -0.7 -1.0
Interest Coverage 9-point trend, -138642.2% -7167.1 -13113.9 -8448.5 · · -7.5 · -12.2 -4.7 -3.5 -4.9 -5.2
效率 3
AMRN 的年度效率数据
指标 趋势 202520242023202220212020201920182017201620152014
Asset Turnover 9-point trend, +23.1% 0.3 0.3 0.4 · · 0.7 · 0.8 1.1 0.8 0.5 0.3
Inventory Turnover 6-point trend, -15.6% · · · · · 1.0 · 1.2 1.8 1.7 1.7 1.2
Receivables Turnover 9-point trend, -81.8% 1.7 1.8 2.3 · · 4.5 · 4.1 5.5 7.7 7.5 9.4
每股 5
AMRN 的年度每股数据
指标 趋势 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, +317.8% $1.10 $1.18 $1.35 · · $1.60 · $0.47 $-0.24 $-0.03 $-0.70 $-0.51
Revenue / Share 9-point trend, +65.1% $0.51 $0.56 $0.75 · · $1.61 · $0.77 $0.67 $0.61 $0.45 $0.31
Cash Flow / Share 9-point trend, +103.9% $0.02 $-0.08 $0.02 · · $-0.06 · $-0.32 $-0.12 $-0.34 $-0.47 $-0.42
Cash / Share 9-point trend, -52.8% $0.32 $0.29 $0.49 · · $0.48 · $0.76 $0.27 $0.36 $0.58 $0.68
EPS (TTM) 12-point trend, +75.0% $-0.09 $-0.20 $-0.15 $-0.26 $0.02 $-0.05 $-0.07 $-0.39 $-0.25 $-0.41 $-0.83 $-0.36
增长率 3
AMRN 的年度增长率数据
指标 趋势 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -30.2% -6.6% -25.5% -16.9% -36.7% -5.0% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +19.2% -16.7% -26.8% -20.6% · · · · · · · · ·
Revenue CAGR 5Y -19.0% · · · · · · · · · · ·
估值 (TTM) 14
AMRN 的年度估值 (TTM)数据
指标 趋势 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +294.2% $214M $229M $307M $369M $583M $614M $430M $229M $181M $130M $82M $54M
Net Income TTM 12-point trend, +31.2% $-39M $-82M $-59M $-106M $8M $-18M $-23M $-116M $-68M $-86M $-115M $-56M
Market Cap 9-point trend, +69.8% $5.81B $4.03B $7.11B · · $38.39B · $88.70B $21.74B $16.59B $6.93B $3.42B
Enterprise Value 6-point trend, +1012.0% · · · · · $37.89B · $88.53B $21.76B $16.60B $6.93B $3.41B
P/E 12-point trend, -184.9% -155.1 -49.0 -116.0 -93.1 3370.0 -1956.0 -6125.7 -697.9 -320.8 -150.2 -45.5 -54.4
P/S 9-point trend, -56.9% 27.2 17.6 23.2 · · 62.5 · 387.0 120.0 127.6 84.8 63.1
P/B 9-point trend, +132.7% 12.7 8.3 12.9 · · 61.2 · 582.3 -333.9 -1831.8 -53.7 -38.7
P / Tangible Book 6-point trend, -79.2% 13.0 8.6 13.4 17.1 41.5 62.6 · · · · · ·
P / Cash Flow 9-point trend, +1924.9% 863.6 -130.0 1033.9 · · -1765.4 · -936.6 -661.9 -231.0 -81.8 -47.3
P / FCF 5-point trend, -2034.1% · · · · · -1745.2 · -936.0 -661.7 -231.0 -81.8 ·
EV / EBITDA 6-point trend, -5328.5% · · · · · -1927.7 · -818.0 -477.6 -252.9 -70.6 -35.5
EV / FCF 5-point trend, -2006.5% · · · · · -1722.4 · -934.2 -662.3 -231.0 -81.8 ·
EV / Revenue 6-point trend, -1.8% · · · · · 61.7 · 386.2 120.1 127.6 84.8 62.9
Earnings Yield 12-point trend, +65.2% -0.64% -2.0% -0.86% -1.1% 0.03% -0.05% -0.02% -0.14% -0.31% -0.67% -2.2% -1.8%

财务报表 损益表、资产负债表、现金流量表 — 年度,近5年

损益表
2025-12-312024-12-312023-12-312022-12-312021-12-31
收入 $214M$229M$307M$369M$583M
毛利率 % 56.6%35.6%53.9%
营业利润率 % -23.5%-40.2%-22.0%
净收入 $-39M$-82M$-59M$-106M$8M
稀释后每股收益 (EPS) $-0.09$-0.20$-0.15$-0.26$0.02
资产负债表
2025-12-312024-12-312023-12-312022-12-312021-12-31
流动比率 3.33.32.8
速动比率 2.22.31.8

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机构持有人 (13F) 90 家申报者 · $59.1M 总计 · 截至 2026年6月30日

在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸;单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存,而非方向性判断。

机构活动 — Q2 2026 与上一季度对比
新仓位 已退出持仓 增加 减少 净股数变动
23 (+15 与上一季度对比) 7 (-12 与上一季度对比) 19 (+1 与上一季度对比) 10 (-3 与上一季度对比) +89K

与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天,外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过,优先显示最近一个已完整报告的季度对。

机构 价值 股份 % 已追踪的13F 类型
Sarissa Capital Management LP $26673916 1673395 45.11% 股份
Kynam Capital Management, LP $8495733 532982 14.37% 股份
Waterfront Wealth Inc. $3183561 213949 5.38% 股份
Brooklands Fund Management Ltd $2741449 177325 4.64% 股份
Eversept Partners, LP $2316018 145296 3.92% 股份
MILLENNIUM MANAGEMENT LLC $1845980 115808 3.12% 股份
TWO SIGMA INVESTMENTS, LP $1602145 100511 2.71% 股份
BNP PARIBAS FINANCIAL MARKETS $1144699 71813 1.94% 股份
CITADEL ADVISORS LLC $971671 60958 1.64% 股份
LCM Capital Management Inc $818710 51362 1.38% 股份
RENAISSANCE TECHNOLOGIES LLC $771002 48369 1.30% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $765120 48000 1.29% 买入期权
George Kaiser Family Foundation $593080 37207 1.00% 股份
JANE STREET GROUP, LLC $523294 32829 0.89% 股份
TWO SIGMA ADVISERS, LP $516265 36995 0.87% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $462276 29001 0.78% 股份
STATE STREET CORP $398755 25016 0.67% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $385748 24200 0.65% 卖出期权
Bleakley Financial Group, LLC $374670 23505 0.63% 股份
State of New Jersey Common Pension Fund D $300931 18879 0.51% 股份
CITADEL ADVISORS LLC $299672 18800 0.51% 卖出期权
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS $292818 18370 0.50% 股份
R Squared Ltd $269992 16938 0.46% 股份
State of Tennessee, Department of Treasury $239164 15004 0.40% 股份
MORGAN STANLEY $237618 14907 0.40% 股份
Quadrature Capital Ltd $236581 14842 0.40% 股份
Quinn Opportunity Partners LLC $228022 14305 0.39% 股份
Cubist Systematic Strategies, LLC $224390 13699 0.38% 股份
EntryPoint Capital, LLC $194882 12226 0.33% 股份
Jump Financial, LLC $191407 12008 0.32% 股份
GEODE CAPITAL MANAGEMENT, LLC $187629 11771 0.32% 股份
WELLS FARGO & COMPANY/MN $179564 11265 0.30% 股份
NJ State Employees Deferred Compensation Plan $178542 10900 0.30% 股份
Verdad Advisers, LP $166270 10431 0.28% 股份
CITADEL ADVISORS LLC $164182 10300 0.28% 买入期权
Steward Partners Investment Advisory, LLC $142025 8910 0.24% 股份
NEW YORK STATE COMMON RETIREMENT FUND $121224 7605 0.21% 股份
OSAIC HOLDINGS, INC. $104537 6559 0.18% 股份
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $92038 5774 0.16% 股份
MERCER GLOBAL ADVISORS INC /ADV $80099 5025 0.14% 股份
UBS Group AG $67171 4214 0.11% 股份
RHUMBLINE ADVISERS $59498 3733 0.10% 股份
NATIONAL BANK OF CANADA /FI/ $40137 2518 0.07% 股份
AMERIPRISE FINANCIAL INC $30318 1902 0.05% 股份
ROYAL BANK OF CANADA $28000 1787 0.05% 股份
GAMMA Investing LLC $25121 1576 0.04% 股份
RAYMOND JAMES FINANCIAL INC $22332 1401 0.04% 股份
NewEdge Advisors, LLC $21471 1347 0.04% 股份
Farther Finance Advisors, LLC $15271 958 0.03% 股份
BlackRock, Inc. $13677 858 0.02% 股份
IFP Advisors, Inc $12975 814 0.02% 股份
Beaird Harris Wealth Management, LLC $11955 750 0.02% 股份
ACADIAN ASSET MANAGEMENT LLC $11467 720984 0.02% 股份
CoreCap Advisors, LLC $8528 535 0.01% 股份
Integrated Wealth Concepts LLC $8449 530 0.01% 股份
JONES FINANCIAL COMPANIES LLLP $7844 493 0.01% 股份
BARCLAYS PLC $4862 305 0.01% 股份
JPMORGAN CHASE & CO $3853 242 0.01% 股份
CWM, LLC $3644 252 0.01% 股份
Westside Investment Management, Inc. $3268 205 0.01% 股份
Global Retirement Partners, LLC $2646 166 0.00% 股份
GROUP ONE TRADING LLC $2072 130 0.00% 股份
HARBOUR INVESTMENTS, INC. $1562 98 0.00% 股份
Federation des caisses Desjardins du Quebec $1435 90 0.00% 股份
Activest Wealth Management $797 50 0.00% 股份
HighMark Wealth Management LLC $797 50 0.00% 股份
Arax Advisory Partners $685 43 0.00% 股份
Darwin Wealth Management, LLC $398 25 0.00% 股份
Continuum Advisory, LLC $303 19 0.00% 股份
Caitong International Asset Management Co., Ltd $271 17 0.00% 股份
SEI INVESTMENTS CO $260 16 0.00% 股份
Hayek Kallen Investment Management $204 12809 0.00% 股份
Atlantic Union Bankshares Corp $192 12 0.00% 股份
Truvestments Capital LLC $191 12 0.00% 股份
Parallel Advisors, LLC $159 10 0.00% 股份
Creative Capital Management Investments LLC $143 9 0.00% 股份
Key Financial Inc $128 8 0.00% 股份
CITIGROUP INC $128 8 0.00% 股份
MCGUIRE CAPITAL ADVISORS INC $112 7 0.00% 股份
EASTERN BANK $112 7 0.00% 股份
Lindbrook Capital, LLC $90 200 0.00% 股份
Oakmont Advisory Group, LLC $80 5 0.00% 股份
Allworth Financial LP $80 5 0.00% 股份
Crewe Advisors LLC $80 5 0.00% 股份
BFSG, LLC $80 5 0.00% 股份
SBI Securities Co., Ltd. $80 5 0.00% 股份
WHITTIER TRUST CO $63 4 0.00% 股份
Caitlin John, LLC $32 2 0.00% 股份
WHITTIER TRUST CO OF NEVADA INC $15 1 0.00% 股份
JFS WEALTH ADVISORS, LLC $15 1 0.00% 股份

公司内部人士 37 位内幕人士 · 17 位高管 · 22 位董事

内部人士 角色 上次活动 持股数量 买入 12个月 卖出 12个月 净额 12个月
Aaron Berg President and CEO 2026年6月26日 M 85648 0 0 $0
Patrick Holt President and CEO 2024年1月22日 P 314426 0 0 $0
Karim Mikhail President and CEO 2023年2月21日 A 283507 0 0 $0
John F Thero President and CEO 2019年11月19日 S 2342285 0 0 $0
Peter L. Fishman SVP, CFO 2026年8月1日 A 7619 0 0 $0
Thomas Charles Reilly EVP and CFO 2024年7月1日 M 94305 0 0 $0
Michael Wayne Kalb SVP and CFO 2019年12月16日 M 21552 0 0 $0
David Paul Keenan EVP, Chief Operating Officer 2026年7月1日 A 13470 0 0 $0
Jonathan Provoost EVP, Chief Legal Officer 2026年7月1日 A 4624 0 0 $0
Steven B Ketchum EVP, Chief Scientific Officer 2026年7月1日 A 42680 0 0 $0
Joseph T Kennedy General Counsel 2019年10月7日 F 125723 0 0 $0
Mark Salyer Chief Commercial Officer 2018年2月1日 A 0 0 $0
Michael James Farrell VP, Finance 2016年2月1日 A 30190 0 0 $0
Paul Huff Chief Commercial Officer 2012年7月26日 A 0 0 0 $0
Stuart D Sedlack Senior Vice President 2012年7月26日 A 0 0 0 $0
Paresh Soni SVP and Head of Development 2012年2月1日 A 0 0 0 $0
Frederick W Ahlholm Vice President Finance 2012年2月1日 A 0 0 0 $0
Oliver O'Connor 董事 2026年4月18日 M 801 0 0 $0
Paul Cohen 董事 2026年4月18日 M 836 0 0 $0
Diane E. Sullivan 董事 2026年4月18日 M 836 0 0 $0
Louis Sterling III 董事 2026年4月18日 M 4049 0 0 $0
Patrice Eadon Bonfiglio 董事 2026年4月18日 M 836 0 0 $0
Keith Horn 董事 2026年4月18日 M 836 0 0 $0
Odysseas D Kostas 董事 2026年4月18日 M 836 0 0 $0
Mark Dipaolo 董事 2025年4月18日 M 401 0 0 $0
Olsen Per Wold 董事 2023年1月10日 M 171027 0 0 $0
David M Stack 董事 2021年6月4日 P 40000 0 0 $0
Joseph S Zakrzewski 董事 2020年1月3日 M 84547 0 0 $0
Lars Ekman 董事 2019年11月12日 M 0 0 0 $0
Kristine Peterson 董事 2019年5月20日 A 0 0 0 $0
Patrick J O'Sullivan 董事 2019年5月20日 A 0 0 $0
VAN HEEK G JAN 董事 2019年5月20日 A 14168 0 0 $0
Dr. James I. Healy 董事 2016年7月11日 A 90000 0 0 $0
GORDON CARL L 董事 2012年9月4日 S 5700 0 0 $0
Joseph Anderson 董事 2012年7月10日 A 11683 0 0 $0
David W Feigal Jr 董事 2011年7月12日 A 0 0 $0
Abingworth LLP 10% 所有者 2012年4月19日 S 1599168 0 0 $0

来自SEC表格3/4/5申报的内部人士;净额=仅公开市场买卖

激进投资者及 5%+ 股东 34 持仓

提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权,意图影响发行人(激进股东持股、董事会活动、并购)。每一行显示该申报人持仓的最新已知状态。

申报人 已申报 持股 状态 目的 申报
Sarissa Capital Management LP, Alexander J Denner ×3 申报 2025年3月25日 8.08% 修订 董事会活动 SEC
2023年2月28日 初始申报 SEC
2023年2月27日 初始申报 SEC
2023年2月21日 初始申报 SEC
OR ×6 申报 2023年2月15日 初始申报 SEC
2023年2月14日 初始申报 SEC
2023年2月10日 初始申报 SEC
2023年1月19日 初始申报 SEC
2022年6月16日 初始申报 SEC
Sofinnova Venture Partners VII, L.P. (“SVP VII”), Sofinnova Management VII, L.L.C. (“SM VII”), Dr. Michael F. Powell (“Powell”), Dr. James I. Healy (“Healy”), Eric P. Buatois (“Buatois”) ×4 申报 2013年8月23日 初始申报 被动投资 SEC
Abingworth LLP 98-051-8585, Abingworth Bioventures V Co-Invest Growth Equity Fund LP 98-057-9772, Abingworth Bioventures V L.P. 98-051-8587, Abingworth Bioequities Master Fund Limited 66-066-0960 ×10 申报 2013年7月22日 初始申报 董事会活动 SEC
Boxer Capital, LLC, Boxer Asset Management Inc., Joseph Lewis ×4 申报 2011年8月24日 初始申报 SEC
OrbiMed Advisors LLC, OrbiMed Capital GP III LLC, Samuel D. Isaly ×14 申报 2011年4月28日 初始申报 SEC
Fountain Healthcare Partners Fund 1, L.P. (“ Fountain ”), Fountain Healthcare Partners Ltd., Manus Rogan, Aidan King, Ena Prosser, Justin Lynch ×2 申报 2010年12月10日 初始申报 SEC
Longitude Capital Partners, LLC (2), Longitude Venture Partners, L.P. (2), Longitude Capital Associates, L.P. (2), Patrick G. Enright (2), Juliet Tammenoms Bakker (2) 2010年10月26日 初始申报 SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.