| GILEAD SCIENCES, INC. |
$136770406 |
4977089 |
25.58% |
股份
|
| FARALLON CAPITAL MANAGEMENT, L.L.C. |
$44094133 |
1604590 |
8.25% |
股份
|
| Paradigm Biocapital Advisors LP |
$42696995 |
1553748 |
7.99% |
股份
|
| Commodore Capital LP |
$38884200 |
1415000 |
7.27% |
股份
|
| RA CAPITAL MANAGEMENT, L.P. |
$28040867 |
1020410 |
5.24% |
股份
|
| JANUS HENDERSON GROUP PLC |
$23479147 |
849309 |
4.39% |
股份
|
| BlackRock, Inc. |
$21072187 |
766819 |
3.94% |
股份
|
| Parkman Healthcare Partners LLC |
$19818054 |
721181 |
3.71% |
股份
|
| VANGUARD GROUP INC |
$19484260 |
572898 |
3.64% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$15359726 |
558942 |
2.87% |
股份
|
| Point72 Asset Management, L.P. |
$12657096 |
460593 |
2.37% |
股份
|
| Seven Fleet Capital Management LP |
$11902879 |
433147 |
2.23% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$8211216 |
298807 |
1.54% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$7707832 |
280424 |
1.44% |
股份
|
| Schonfeld Strategic Advisors LLC |
$6654363 |
242153 |
1.24% |
股份
|
| AMERIPRISE FINANCIAL INC |
$6320400 |
230000 |
1.18% |
股份
|
| DV EQUITIES, LLC |
$6221884 |
226415 |
1.16% |
股份
|
| Aberdeen Group plc |
$5689652 |
207047 |
1.06% |
股份
|
| Affinity Asset Advisors, LLC |
$5221200 |
190000 |
0.98% |
股份
|
| B Group, Inc. |
$4828401 |
175706 |
0.90% |
股份
|
| STATE STREET CORP |
$4724664 |
171931 |
0.88% |
股份
|
| STEMPOINT CAPITAL LP |
$4681987 |
170378 |
0.88% |
股份
|
| Squadron Capital Management LLC |
$4396800 |
160000 |
0.82% |
股份
|
| Woodline Partners LP |
$4143434 |
150780 |
0.77% |
股份
|
| Driehaus Capital Management LLC |
$4122000 |
150000 |
0.77% |
股份
|
| Ally Bridge Group (NY) LLC |
$3847200 |
140000 |
0.72% |
股份
|
| GOLDMAN SACHS GROUP INC |
$3787651 |
137833 |
0.71% |
股份
|
| NORTHERN TRUST CORP |
$3380837 |
123029 |
0.63% |
股份
|
| FRANKLIN RESOURCES INC |
$3110736 |
113200 |
0.58% |
股份
|
| CITADEL ADVISORS LLC |
$2635524 |
95907 |
0.49% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$2504884 |
91153 |
0.47% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$2032696 |
73970 |
0.38% |
股份
|
| HighVista Strategies LLC |
$2017170 |
73405 |
0.38% |
股份
|
| Qube Research & Technologies Ltd |
$1414890 |
51488 |
0.26% |
股份
|
| MONIMUS CAPITAL MANAGEMENT, LP |
$1307498 |
47580 |
0.24% |
股份
|
| Trexquant Investment LP |
$1254764 |
45661 |
0.23% |
股份
|
| JPMORGAN CHASE & CO |
$1250540 |
46385 |
0.23% |
股份
|
| MORGAN STANLEY |
$1242618 |
45219 |
0.23% |
股份
|
| XTX Topco Ltd |
$1179387 |
42918 |
0.22% |
股份
|
| UBS Group AG |
$1148829 |
41806 |
0.21% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$1083839 |
39441 |
0.20% |
股份
|
| Squarepoint Ops LLC |
$940201 |
34214 |
0.18% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$800437 |
29128 |
0.15% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$665098 |
24203 |
0.12% |
股份
|
| Bank of New York Mellon Corp |
$659933 |
24015 |
0.12% |
股份
|
| Connor, Clark & Lunn Investment Management Ltd. |
$653062 |
23765 |
0.12% |
股份
|
| Caption Management, LLC |
$627341 |
22829 |
0.12% |
股份
|
| ADAR1 Capital Management, LLC |
$561884 |
20447 |
0.11% |
股份
|
| Palumbo Wealth Management LLC |
$545891 |
19865 |
0.10% |
股份
|
| CITADEL ADVISORS LLC |
$508380 |
18500 |
0.10% |
买入期权
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$502884 |
18300 |
0.09% |
卖出期权
|
| TWO SIGMA INVESTMENTS, LP |
$490738 |
17858 |
0.09% |
股份
|
| Engineers Gate Manager LP |
$488210 |
17766 |
0.09% |
股份
|
| MARSHALL WACE, LLP |
$487357 |
17735 |
0.09% |
股份
|
| Nuveen, LLC |
$463725 |
16875 |
0.09% |
股份
|
| Eversept Partners, LP |
$453695 |
16510 |
0.08% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$415745 |
15129 |
0.08% |
股份
|
| Cubist Systematic Strategies, LLC |
$413716 |
16161 |
0.08% |
股份
|
| Virtus Investment Advisers, LLC |
$391617 |
14251 |
0.07% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$363808 |
13239 |
0.07% |
股份
|
| Invesco Ltd. |
$326023 |
11864 |
0.06% |
股份
|
| RHUMBLINE ADVISERS |
$318486 |
11590 |
0.06% |
股份
|
| Integrated Quantitative Investments LLC |
$276943 |
10078 |
0.05% |
股份
|
| DEUTSCHE BANK AG\ |
$264220 |
9615 |
0.05% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$262901 |
9567 |
0.05% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$239076 |
8700 |
0.04% |
买入期权
|
| CANADA PENSION PLAN INVESTMENT BOARD |
$233580 |
8500 |
0.04% |
股份
|
| EntryPoint Capital, LLC |
$227672 |
8285 |
0.04% |
股份
|
| WELLS FARGO & COMPANY/MN |
$226792 |
8253 |
0.04% |
股份
|
| Brevan Howard Capital Management LP |
$213382 |
7765 |
0.04% |
股份
|
| Persistent Asset Partners Ltd |
$190766 |
6942 |
0.04% |
股份
|
| BARCLAYS PLC |
$168536 |
6133 |
0.03% |
股份
|
| MetLife Investment Management, LLC |
$161720 |
5885 |
0.03% |
股份
|
| Vanguard Global Advisers, LLC |
$126820 |
4615 |
0.02% |
股份
|
| CITIGROUP INC |
$125144 |
4554 |
0.02% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$124182 |
4519 |
0.02% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$115416 |
4200 |
0.02% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$79884 |
2907 |
0.01% |
股份
|
| Legal & General Group Plc |
$26326 |
958 |
0.00% |
股份
|
| Ameritas Investment Partners, Inc. |
$24595 |
895 |
0.00% |
股份
|
| Russell Investments Group, Ltd. |
$21654 |
788 |
0.00% |
股份
|
| HSBC HOLDINGS PLC |
$17104 |
16935 |
0.00% |
股份
|
| Tower Research Capital LLC (TRC) |
$14564 |
530 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$12000 |
440 |
0.00% |
股份
|
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO |
$7145 |
260 |
0.00% |
股份
|
| Accent Capital Management, LLC |
$5826 |
212 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$5469 |
199 |
0.00% |
股份
|
| Truvestments Capital LLC |
$5304 |
193 |
0.00% |
股份
|
| FMR LLC |
$4891 |
178 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$3737 |
136 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$2748 |
100 |
0.00% |
股份
|
| Quarry LP |
$2061 |
75 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$2061 |
75 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$1511 |
55 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$1180 |
42931 |
0.00% |
股份
|
| Point72 Europe (London) LLP |
$332 |
13 |
0.00% |
股份
|
| Allworth Financial LP |
$275 |
10 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$226 |
8203 |
0.00% |
股份
|