AVTX — 机构持有人 (13F)
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| FMR LLC | $94251992 | 5100216 | 7.16% | 股份 |
| BlackRock, Inc. | $80675418 | 4365553 | 6.13% | 股份 |
| Deep Track Capital, LP | $66712800 | 3610000 | 5.07% | 股份 |
| Caligan Partners LP | $58468244 | 3163866 | 4.44% | 股份 |
| TCG Crossover Management, LLC | $55756378 | 3017120 | 4.24% | 股份 |
| Affinity Asset Advisors, LLC | $53592000 | 2900000 | 4.07% | 股份 |
| STATE STREET CORP | $53394024 | 2889287 | 4.06% | 股份 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $46163040 | 2498000 | 3.51% | 股份 |
| Point72 Asset Management, L.P. | $44112240 | 2387026 | 3.35% | 股份 |
| Avoro Capital Advisors LLC | $43119994 | 2333333 | 3.28% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $41843266 | 2264246 | 3.18% | 股份 |
| BVF INC/IL | $38356072 | 2075545 | 2.92% | 股份 |
| BANK OF AMERICA CORP /DE/ | $35367561 | 1913829 | 2.69% | 股份 |
| Nantahala Capital Management, LLC | $34414380 | 1862250 | 2.62% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $31951920 | 1729000 | 2.43% | 股份 |
| Soleus Capital Management, L.P. | $30583993 | 1654978 | 2.32% | 股份 |
| BRAIDWELL LP | $30107283 | 1629182 | 2.29% | 股份 |
| ALLIANCEBERNSTEIN L.P. | $23297533 | 1260689 | 1.77% | 股份 |
| UBS Group AG | $22343410 | 1209059 | 1.70% | 股份 |
| Logos Global Management LP | $21252000 | 1150000 | 1.62% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $20428430 | 1105118 | 1.55% | 股份 |
| Commodore Capital LP | $18818535 | 1018319 | 1.43% | 股份 |
| RA CAPITAL MANAGEMENT, L.P. | $18480000 | 1000000 | 1.40% | 股份 |
| GOLDMAN SACHS GROUP INC | $17487993 | 946320 | 1.33% | 股份 |
| Trails Edge Capital Partners, LP | $16481961 | 891881 | 1.25% | 股份 |
| AMERIPRISE FINANCIAL INC | $16473165 | 891405 | 1.25% | 股份 |
| Balyasny Asset Management L.P. | $15924419 | 861711 | 1.21% | 股份 |
| VANGUARD GROUP INC | $14602165 | 804084 | 1.11% | 股份 |
| Vestal Point Capital, LP | $14322000 | 775000 | 1.09% | 股份 |
| Seven Fleet Capital Management LP | $14243737 | 770765 | 1.08% | 股份 |
| Parkman Healthcare Partners LLC | $14161039 | 766290 | 1.08% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $12973902 | 702051 | 0.99% | 股份 |
| Squarepoint Ops LLC | $10889248 | 589245 | 0.83% | 股份 |
| BAKER BROS. ADVISORS LP | $10164000 | 550000 | 0.77% | 股份 |
| SILVERARC CAPITAL MANAGEMENT, LLC | $9247429 | 500402 | 0.70% | 股份 |
| Davern Capital Partners, LP | $8660948 | 468666 | 0.66% | 股份 |
| Pivotal bioVenture Partners Investment Advisor LLC | $8020930 | 434033 | 0.61% | 股份 |
| FRANKLIN RESOURCES INC | $7469450 | 404191 | 0.57% | 股份 |
| Boxer Capital Management, LLC | $6930000 | 375000 | 0.53% | 股份 |
| RENAISSANCE TECHNOLOGIES LLC | $6601056 | 357200 | 0.50% | 股份 |
| Caption Management, LLC | $6371904 | 344800 | 0.48% | 卖出期权 |
| NORTHERN TRUST CORP | $6366748 | 344521 | 0.48% | 股份 |
| DV EQUITIES, LLC | $6139296 | 332213 | 0.47% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $6002452 | 324808 | 0.46% | 股份 |
| Velan Capital Investment Management LP | $5995873 | 324452 | 0.46% | 股份 |
| CITADEL ADVISORS LLC | $5984434 | 323833 | 0.45% | 股份 |
| Schonfeld Strategic Advisors LLC | $5728947 | 310008 | 0.44% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $5261293 | 284702 | 0.40% | 股份 |
| Vivo Capital, LLC | $5082000 | 275000 | 0.39% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4470312 | 241900 | 0.34% | 买入期权 |
| Eagle Health Investments LP | $4344519 | 235093 | 0.33% | 股份 |
| SPHERA FUNDS MANAGEMENT LTD. | $4292793 | 232294 | 0.33% | 股份 |
| PERCEPTIVE ADVISORS LLC | $4062144 | 219813 | 0.31% | 股份 |
| Caption Management, LLC | $3880800 | 210000 | 0.29% | 股份 |
| Jump Financial, LLC | $3731149 | 201902 | 0.28% | 股份 |
| NAN FUNG TRINITY (HK) LTD | $3492720 | 189000 | 0.27% | 股份 |
| ACUTA CAPITAL PARTNERS, LLC | $3442972 | 186308 | 0.26% | 股份 |
| Walleye Capital LLC | $3430128 | 185613 | 0.26% | 股份 |
| RTW INVESTMENTS, LP | $3234000 | 175000 | 0.25% | 股份 |
| Ally Bridge Group (NY) LLC | $2772000 | 150000 | 0.21% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2540538 | 137475 | 0.19% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $2477928 | 134087 | 0.19% | 股份 |
| CenterBook Partners LP | $2455419 | 132869 | 0.19% | 股份 |
| MORGAN STANLEY | $2366826 | 128075 | 0.18% | 股份 |
| Moody Aldrich Partners LLC | $2320755 | 125582 | 0.18% | 股份 |
| HighVista Strategies LLC | $2265832 | 122610 | 0.17% | 股份 |
| Aberdeen Group plc | $2257683 | 122169 | 0.17% | 股份 |
| SECTORAL ASSET MANAGEMENT INC | $2216177 | 119923 | 0.17% | 股份 |
| CITADEL ADVISORS LLC | $2080848 | 112600 | 0.16% | 买入期权 |
| WELLINGTON MANAGEMENT GROUP LLP | $1945224 | 105261 | 0.15% | 股份 |
| Bank of New York Mellon Corp | $1897023 | 102653 | 0.14% | 股份 |
| Nuveen, LLC | $1859698 | 100633 | 0.14% | 股份 |
| LMR Partners LLP | $1738968 | 94100 | 0.13% | 买入期权 |
| Ikarian Capital, LLC | $1666581 | 90183 | 0.13% | 股份 |
| TD Asset Management Inc | $1431720 | 77474 | 0.11% | 股份 |
| CITIGROUP INC | $1275378 | 69014 | 0.10% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $1239897 | 67094 | 0.09% | 股份 |
| JANE STREET GROUP, LLC | $1068144 | 57800 | 0.08% | 买入期权 |
| Rafferty Asset Management, LLC | $1042475 | 56411 | 0.08% | 股份 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $994206 | 53799 | 0.08% | 股份 |
| RHUMBLINE ADVISERS | $984789 | 53290 | 0.07% | 股份 |
| XTX Topco Ltd | $971734 | 52583 | 0.07% | 股份 |
| TWO SIGMA ADVISERS, LP | $897104 | 49400 | 0.07% | 股份 |
| DEUTSCHE BANK AG\ | $760747 | 41166 | 0.06% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $706919 | 38158 | 0.05% | 股份 |
| Verition Fund Management LLC | $706675 | 38240 | 0.05% | 股份 |
| Man Group plc | $681468 | 36876 | 0.05% | 股份 |
| WELLS FARGO & COMPANY/MN | $675924 | 36576 | 0.05% | 股份 |
| Verdad Advisers, LP | $606643 | 32827 | 0.05% | 股份 |
| LMR Partners LLP | $554400 | 30000 | 0.04% | 卖出期权 |
| PROFUND ADVISORS LLC | $523150 | 28309 | 0.04% | 股份 |
| GLENMEDE TRUST CO NA | $522614 | 28280 | 0.04% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $503155 | 27227 | 0.04% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $480465 | 25712 | 0.04% | 股份 |
| Persistent Asset Partners Ltd | $453573 | 24544 | 0.03% | 股份 |
| MetLife Investment Management, LLC | $452742 | 24499 | 0.03% | 股份 |
| ENVESTNET ASSET MANAGEMENT INC | $416521 | 22539 | 0.03% | 股份 |
| Invesco Ltd. | $410736 | 22226 | 0.03% | 股份 |
| Virtus Investment Advisers, LLC | $409665 | 22168 | 0.03% | 股份 |
| Vanguard Global Advisers, LLC | $369785 | 20010 | 0.03% | 股份 |
| JPMORGAN CHASE & CO | $350018 | 18145 | 0.03% | 股份 |
| SEI INVESTMENTS CO | $331365 | 17931 | 0.03% | 股份 |
| BARCLAYS PLC | $329147 | 17811 | 0.03% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $304920 | 16500 | 0.02% | 卖出期权 |
| ExodusPoint Capital Management, LP | $304828 | 16495 | 0.02% | 股份 |
| Quadrature Capital Ltd | $284684 | 15405 | 0.02% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $271656 | 14700 | 0.02% | 股份 |
| CITADEL ADVISORS LLC | $255024 | 13800 | 0.02% | 卖出期权 |
| Jain Global LLC | $234437 | 12686 | 0.02% | 股份 |
| Woodline Partners LP | $231813 | 12544 | 0.02% | 股份 |
| Police & Firemen's Retirement System of New Jersey | $227748 | 12324 | 0.02% | 股份 |
| FOX RUN MANAGEMENT, L.L.C. | $196609 | 10639 | 0.01% | 股份 |
| Lynx1 Capital Management LP | $186648 | 10100 | 0.01% | 股份 |
| Eversept Partners, LP | $184800 | 10000 | 0.01% | 股份 |
| US BANCORP \DE\ | $105040 | 5684 | 0.01% | 股份 |
| Byrne Asset Management LLC | $88667 | 4798 | 0.01% | 股份 |
| Legal & General Group Plc | $74896 | 4055 | 0.01% | 股份 |
| Ameritas Investment Partners, Inc. | $70076 | 3792 | 0.01% | 股份 |
| Russell Investments Group, Ltd. | $61741 | 3341 | 0.00% | 股份 |
| Allostery Investments LP | $44910 | 9000 | 0.00% | 股份 |
| PFS Partners, LLC | $36960 | 2000 | 0.00% | 股份 |
| Tower Research Capital LLC (TRC) | $28496 | 1542 | 0.00% | 股份 |
| ROYAL BANK OF CANADA | $26000 | 1365 | 0.00% | 股份 |
| PRICE T ROWE ASSOCIATES INC /MD/ | $24241 | 1311715 | 0.00% | 股份 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $10626 | 575 | 0.00% | 股份 |
| Sterling Capital Management LLC | $9055 | 490 | 0.00% | 股份 |
| Versant Capital Management, Inc | $782 | 51 | 0.00% | 股份 |
| ROTHSCHILD INVESTMENT LLC | $647 | 35 | 0.00% | 股份 |
| EverSource Wealth Advisors, LLC | $647 | 35 | 0.00% | 股份 |
| Fortitude Family Office, LLC | $554 | 30 | 0.00% | 股份 |
| FIFTH THIRD BANCORP | $536 | 29 | 0.00% | 股份 |
| ASSETMARK, INC | $407 | 22 | 0.00% | 股份 |
| OSAIC HOLDINGS, INC. | $18 | 1 | 0.00% | 股份 |
| Activest Wealth Management | $18 | 1 | 0.00% | 股份 |
| Parallel Advisors, LLC | $18 | 1 | 0.00% | 股份 |
| Key Financial Inc | $18 | 1 | 0.00% | 股份 |
| Silver Grove Financial Group, Inc. | $18 | 1 | 0.00% | 股份 |
| Pacer Advisors, Inc. | $17 | 942 | 0.00% | 股份 |