| EQT Fund Management S.a r.l. |
$70281680 |
5288313 |
14.12% |
股份
|
| RA CAPITAL MANAGEMENT, L.P. |
$46443739 |
3494638 |
9.33% |
股份
|
| SymBiosis Capital Partners, LLC |
$29445086 |
1280778 |
5.92% |
股份
|
| Pivotal bioVenture Partners Investment Advisor LLC |
$25609072 |
1926943 |
5.15% |
股份
|
| JPMORGAN CHASE & CO |
$23374637 |
1553132 |
4.70% |
股份
|
| JANUS HENDERSON GROUP PLC |
$20615133 |
896700 |
4.14% |
股份
|
| RTW INVESTMENTS, LP |
$19964703 |
1502235 |
4.01% |
股份
|
| Nan Fung Group Holdings Ltd |
$19151315 |
1441032 |
3.85% |
股份
|
| Point72 Asset Management, L.P. |
$19071801 |
1435049 |
3.83% |
股份
|
| ANDERA PARTNERS |
$18499547 |
1391990 |
3.72% |
股份
|
| EVENTIDE ASSET MANAGEMENT, LLC |
$16069325 |
1209129 |
3.23% |
股份
|
| Vestal Point Capital, LP |
$13290000 |
1000000 |
2.67% |
股份
|
| BlackRock, Inc. |
$11782090 |
886538 |
2.37% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$11720385 |
881895 |
2.36% |
股份
|
| BAKER BROS. ADVISORS LP |
$11261813 |
847390 |
2.26% |
股份
|
| Defilade Capital Management, L.P. |
$10540897 |
793145 |
2.12% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$10034211 |
755018 |
2.02% |
股份
|
| Alyeska Investment Group, L.P. |
$9361808 |
704425 |
1.88% |
股份
|
| VANGUARD GROUP INC |
$8604067 |
502574 |
1.73% |
股份
|
| Affinity Asset Advisors, LLC |
$6646329 |
500100 |
1.34% |
卖出期权
|
| Balyasny Asset Management L.P. |
$6073729 |
457015 |
1.22% |
股份
|
| Velan Capital Investment Management LP |
$5930729 |
446255 |
1.19% |
股份
|
| UBS Group AG |
$5496119 |
413553 |
1.10% |
股份
|
| FEDERATED HERMES, INC. |
$4319250 |
325000 |
0.87% |
股份
|
| GREAT POINT PARTNERS LLC |
$4319250 |
325000 |
0.87% |
股份
|
| Freestone Grove Partners LP |
$4071099 |
306328 |
0.82% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$4011321 |
301759 |
0.81% |
股份
|
| STATE STREET CORP |
$3900828 |
293516 |
0.78% |
股份
|
| MORGAN STANLEY |
$3856412 |
290174 |
0.77% |
股份
|
| JANE STREET GROUP, LLC |
$3089128 |
232440 |
0.62% |
股份
|
| GOLDMAN SACHS GROUP INC |
$2564904 |
192995 |
0.52% |
股份
|
| Blue Owl Capital Holdings LP |
$2392200 |
180000 |
0.48% |
股份
|
| BARCLAYS PLC |
$2375322 |
178730 |
0.48% |
股份
|
| Eversept Partners, LP |
$2318573 |
174460 |
0.47% |
股份
|
| Balyasny Asset Management L.P. |
$2259300 |
170000 |
0.45% |
买入期权
|
| Caption Management, LLC |
$2204811 |
165900 |
0.44% |
买入期权
|
| ORBIMED ADVISORS LLC |
$2139690 |
161000 |
0.43% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$1772222 |
133350 |
0.36% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1768527 |
133072 |
0.36% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$1593830 |
119927 |
0.32% |
股份
|
| NEXTBio Capital Management LP |
$1582347 |
119063 |
0.32% |
股份
|
| LMR Partners LLP |
$1574014 |
118436 |
0.32% |
股份
|
| Longaeva Partners L.P. |
$1549760 |
116611 |
0.31% |
股份
|
| Holocene Advisors, LP |
$1476944 |
111132 |
0.30% |
股份
|
| ADAR1 Capital Management, LLC |
$1382625 |
104035 |
0.28% |
股份
|
| NORTHERN TRUST CORP |
$1347659 |
101404 |
0.27% |
股份
|
| SEVEN GRAND MANAGERS, LLC |
$1203649 |
90568 |
0.24% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$1172165 |
88199 |
0.24% |
股份
|
| AMERIPRISE FINANCIAL INC |
$1156469 |
87018 |
0.23% |
股份
|
| Avidity Partners Management LP |
$996750 |
75000 |
0.20% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$956880 |
72000 |
0.19% |
买入期权
|
| Quadrature Capital Ltd |
$921143 |
69311 |
0.19% |
股份
|
| XTX Topco Ltd |
$806623 |
60694 |
0.16% |
股份
|
| TD Asset Management Inc |
$806198 |
60662 |
0.16% |
股份
|
| CANTOR FITZGERALD, L. P. |
$688369 |
51796 |
0.14% |
股份
|
| Burkehill Global Management, LP |
$664500 |
50000 |
0.13% |
股份
|
| Caption Management, LLC |
$637920 |
48000 |
0.13% |
卖出期权
|
| Squarepoint Ops LLC |
$633960 |
47702 |
0.13% |
股份
|
| Verition Fund Management LLC |
$583909 |
43936 |
0.12% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$538245 |
40500 |
0.11% |
卖出期权
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$517087 |
38908 |
0.10% |
股份
|
| CITADEL ADVISORS LLC |
$494388 |
37200 |
0.10% |
卖出期权
|
| ALPS ADVISORS INC |
$485856 |
36558 |
0.10% |
股份
|
| Caption Management, LLC |
$406421 |
30581 |
0.08% |
股份
|
| Jump Financial, LLC |
$401358 |
30200 |
0.08% |
股份
|
| Qube Research & Technologies Ltd |
$400228 |
30115 |
0.08% |
股份
|
| JANE STREET GROUP, LLC |
$388068 |
29200 |
0.08% |
买入期权
|
| Y-Intercept (Hong Kong) Ltd |
$377409 |
28398 |
0.08% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$362322 |
15760 |
0.07% |
股份
|
| Bank of New York Mellon Corp |
$339572 |
25551 |
0.07% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$339241 |
25526 |
0.07% |
股份
|
| J. Safra Sarasin Holding AG |
$321844 |
24217 |
0.06% |
股份
|
| Cinctive Capital Management LP |
$313086 |
23558 |
0.06% |
股份
|
| SPHERA FUNDS MANAGEMENT LTD. |
$300779 |
22632 |
0.06% |
股份
|
| Swiss National Bank |
$288393 |
21700 |
0.06% |
股份
|
| Nuveen, LLC |
$277748 |
20899 |
0.06% |
股份
|
| Virtus Investment Advisers, LLC |
$219285 |
16500 |
0.04% |
股份
|
| ExodusPoint Capital Management, LP |
$202367 |
15227 |
0.04% |
股份
|
| RHUMBLINE ADVISERS |
$192628 |
14495 |
0.04% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$175215 |
13184 |
0.04% |
股份
|
| DEUTSCHE BANK AG\ |
$167600 |
12611 |
0.03% |
股份
|
| WELLS FARGO & COMPANY/MN |
$160357 |
12066 |
0.03% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$154961 |
11660 |
0.03% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$144436 |
10868 |
0.03% |
股份
|
| CITADEL ADVISORS LLC |
$142522 |
10724 |
0.03% |
股份
|
| Legal & General Group Plc |
$113244 |
8521 |
0.02% |
股份
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$106400 |
8006 |
0.02% |
股份
|
| Quantbot Technologies LP |
$101536 |
7640 |
0.02% |
股份
|
| MetLife Investment Management, LLC |
$93336 |
7023 |
0.02% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$88844 |
6685 |
0.02% |
股份
|
| CITIGROUP INC |
$83089 |
6252 |
0.02% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$77587 |
5838 |
0.02% |
股份
|
| NATIXIS |
$69355 |
5044 |
0.01% |
股份
|
| TORONTO DOMINION BANK |
$65121 |
4900 |
0.01% |
买入期权
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$57147 |
4300 |
0.01% |
股份
|
| Russell Investments Group, Ltd. |
$55751 |
4195 |
0.01% |
股份
|
| Vanguard Global Advisers, LLC |
$49970 |
3760 |
0.01% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$39950 |
3006 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$38169 |
2872 |
0.01% |
股份
|
| KLP KAPITALFORVALTNING AS |
$31896 |
2400 |
0.01% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$25796 |
1940939 |
0.01% |
股份
|
| Mitsubishi UFJ Asset Management Co., Ltd. |
$23922 |
1800 |
0.00% |
股份
|
| Ameritas Investment Partners, Inc. |
$11363 |
855 |
0.00% |
股份
|
| State of Wyoming |
$11137 |
838 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$9000 |
692 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$3841 |
289 |
0.00% |
股份
|
| FMR LLC |
$2180 |
164 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$1223 |
92 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$1063 |
80 |
0.00% |
股份
|
| Quarry LP |
$864 |
65 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$598 |
45 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$385 |
29 |
0.00% |
股份
|
| COMERICA BANK |
$330 |
20 |
0.00% |
股份
|
| GAMMA Investing LLC |
$319 |
24 |
0.00% |
股份
|
| FIFTH THIRD BANCORP |
$273 |
21 |
0.00% |
股份
|
| CWM, LLC |
$161 |
7 |
0.00% |
股份
|
| Allworth Financial LP |
$27 |
2 |
0.00% |
股份
|
| Arax Advisory Partners |
$13 |
1 |
0.00% |
股份
|