GHRS — 机构持有人 (13F)
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| Lynx1 Capital Management LP | $356517181 | 13263288 | 25.76% | 股份 |
| BVF INC/IL | $232516247 | 8650158 | 16.80% | 股份 |
| RA CAPITAL MANAGEMENT, L.P. | $205277533 | 7636813 | 14.83% | 股份 |
| FMR LLC | $160662969 | 5977045 | 11.61% | 股份 |
| RTW INVESTMENTS, LP | $159500947 | 5933815 | 11.52% | 股份 |
| Deep Track Capital, LP | $89600018 | 3333334 | 6.47% | 股份 |
| Avoro Capital Advisors LLC | $48384000 | 1800000 | 3.50% | 股份 |
| Foresite Capital Management VI LLC | $25280452 | 940493 | 1.83% | 股份 |
| Jefferies Financial Group Inc. | $19146624 | 712300 | 1.38% | 股份 |
| BlackRock, Inc. | $12910116 | 480287 | 0.93% | 股份 |
| UBS Group AG | $12832727 | 477408 | 0.93% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $8692965 | 323399 | 0.63% | 股份 |
| BRAIDWELL LP | $5570611 | 207240 | 0.40% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $5432529 | 202103 | 0.39% | 股份 |
| JANE STREET GROUP, LLC | $4568283 | 169951 | 0.33% | 股份 |
| HighVista Strategies LLC | $4267737 | 158770 | 0.31% | 股份 |
| Trexquant Investment LP | $4133257 | 153767 | 0.30% | 股份 |
| GOLDMAN SACHS GROUP INC | $3996330 | 148673 | 0.29% | 股份 |
| XTX Topco Ltd | $2338184 | 86986 | 0.17% | 股份 |
| CITADEL ADVISORS LLC | $2310390 | 85952 | 0.17% | 股份 |
| AdvisorShares Investments LLC | $1915657 | 71267 | 0.14% | 股份 |
| CenterBook Partners LP | $1866440 | 69436 | 0.13% | 股份 |
| MORGAN STANLEY | $1403620 | 52218 | 0.10% | 股份 |
| Point72 Asset Management, L.P. | $1367708 | 50882 | 0.10% | 股份 |
| MARSHALL WACE, LLP | $1255215 | 46697 | 0.09% | 股份 |
| Qube Research & Technologies Ltd | $1181322 | 43948 | 0.09% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $1088183 | 40483 | 0.08% | 股份 |
| TUDOR INVESTMENT CORP ET AL | $921393 | 34278 | 0.07% | 股份 |
| NORTHERN TRUST CORP | $855967 | 31844 | 0.06% | 股份 |
| JANE STREET GROUP, LLC | $787584 | 29300 | 0.06% | 买入期权 |
| D. E. Shaw & Co., Inc. | $681274 | 25345 | 0.05% | 股份 |
| Quadrature Capital Ltd | $567625 | 21117 | 0.04% | 股份 |
| JPMORGAN CHASE & CO | $534985 | 18778 | 0.04% | 股份 |
| CITADEL ADVISORS LLC | $532224 | 19800 | 0.04% | 买入期权 |
| Squarepoint Ops LLC | $495398 | 18430 | 0.04% | 股份 |
| Virtus Investment Advisers, LLC | $416425 | 15492 | 0.03% | 股份 |
| LETKO, BROSSEAU & ASSOCIATES INC | $414624 | 15425 | 0.03% | 股份 |
| China Universal Asset Management Co., Ltd. | $360703 | 13419 | 0.03% | 股份 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $360192 | 13400 | 0.03% | 买入期权 |
| JANE STREET GROUP, LLC | $360192 | 13400 | 0.03% | 卖出期权 |
| HighTower Advisors, LLC | $341376 | 12700 | 0.02% | 股份 |
| Cubist Systematic Strategies, LLC | $325068 | 22732 | 0.02% | 股份 |
| STATE STREET CORP | $300061 | 11163 | 0.02% | 股份 |
| Lion Point Capital, LP | $274176 | 10200 | 0.02% | 股份 |
| Eversept Partners, LP | $233103 | 8672 | 0.02% | 股份 |
| HSBC HOLDINGS PLC | $216420 | 7847 | 0.02% | 股份 |
| BARCLAYS PLC | $160661 | 5977 | 0.01% | 股份 |
| ROYAL BANK OF CANADA | $158000 | 5877 | 0.01% | 股份 |
| OSAIC HOLDINGS, INC. | $155232 | 5775 | 0.01% | 股份 |
| SIMPLEX TRADING, LLC | $127384 | 4739 | 0.01% | 股份 |
| Mirae Asset Global Investments Co., Ltd. | $82468 | 3068 | 0.01% | 股份 |
| North Star Investment Management Corp. | $59136 | 2200 | 0.00% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $45615 | 1697 | 0.00% | 股份 |
| CITIGROUP INC | $43384 | 1614 | 0.00% | 股份 |
| GF FUND MANAGEMENT CO. LTD. | $35347 | 1315 | 0.00% | 股份 |
| WELLS FARGO & COMPANY/MN | $33600 | 1250 | 0.00% | 股份 |
| JONES FINANCIAL COMPANIES LLLP | $21871 | 775 | 0.00% | 股份 |
| HARBOUR INVESTMENTS, INC. | $21504 | 800 | 0.00% | 股份 |
| Tower Research Capital LLC (TRC) | $13843 | 515 | 0.00% | 股份 |
| SBI Securities Co., Ltd. | $11048 | 411 | 0.00% | 股份 |
| HOLLENCREST CAPITAL MANAGEMENT | $6720 | 250 | 0.00% | 股份 |
| Federation des caisses Desjardins du Quebec | $5510 | 205 | 0.00% | 股份 |
| Farther Finance Advisors, LLC | $2688 | 100 | 0.00% | 股份 |
| HRT FINANCIAL LP | $1757 | 65375 | 0.00% | 股份 |
| Cornerstone Financial Management LLC | $860 | 32 | 0.00% | 股份 |
| Caitong International Asset Management Co., Ltd | $511 | 19 | 0.00% | 股份 |