| Lynx1 Capital Management LP |
$20274741 |
1538296 |
9.51% |
股份
|
| Qiming U.S. Ventures Management, LLC |
$17627591 |
368085 |
8.27% |
股份
|
| NEA Management Company, LLC |
$17106230 |
1297893 |
8.02% |
股份
|
| Venrock Adviser, LLC |
$13305210 |
1009500 |
6.24% |
股份
|
| Atlas Venture Life Science Advisors, LLC |
$12690811 |
962884 |
5.95% |
股份
|
| Balyasny Asset Management L.P. |
$12544500 |
951783 |
5.88% |
股份
|
| BlackRock, Inc. |
$10776245 |
817621 |
5.05% |
股份
|
| Affinity Asset Advisors, LLC |
$9316995 |
706904 |
4.37% |
股份
|
| Nantahala Capital Management, LLC |
$8699274 |
660036 |
4.08% |
股份
|
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
$7129958 |
540968 |
3.34% |
股份
|
| ADAR1 Capital Management, LLC |
$7117912 |
540054 |
3.34% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$5993974 |
454778 |
2.81% |
股份
|
| Driehaus Capital Management LLC |
$5931593 |
450045 |
2.78% |
股份
|
| TCG Crossover Management, LLC |
$5486847 |
416301 |
2.57% |
股份
|
| Kalehua Capital Management LLC |
$5338427 |
405040 |
2.50% |
股份
|
| Siren, L.L.C. |
$4582923 |
347718 |
2.15% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$3940478 |
298974 |
1.85% |
股份
|
| VANGUARD GROUP INC |
$3922009 |
489639 |
1.84% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$3913148 |
296870 |
1.84% |
股份
|
| 72 Investment Holdings, LLC |
$3648633 |
276831 |
1.71% |
股份
|
| STATE STREET CORP |
$3065497 |
232587 |
1.44% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$2946402 |
223551 |
1.38% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$2346976 |
178071 |
1.10% |
股份
|
| JPMORGAN CHASE & CO |
$1645760 |
124726 |
0.77% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$1560960 |
118434 |
0.73% |
股份
|
| GOLDMAN SACHS GROUP INC |
$1541836 |
116983 |
0.72% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$1456706 |
110524 |
0.68% |
股份
|
| UBS Group AG |
$1389871 |
105453 |
0.65% |
股份
|
| NORTHERN TRUST CORP |
$1161013 |
88089 |
0.54% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$987195 |
74901 |
0.46% |
股份
|
| CITADEL ADVISORS LLC |
$935780 |
71000 |
0.44% |
买入期权
|
| F/m Investments LLC |
$837747 |
63562 |
0.39% |
股份
|
| EMERALD MUTUAL FUND ADVISERS TRUST |
$837747 |
63562 |
0.39% |
股份
|
| Walleye Capital LLC |
$715529 |
54289 |
0.34% |
股份
|
| Quantinno Capital Management LP |
$694850 |
52720 |
0.33% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$681498 |
51707 |
0.32% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$644765 |
48920 |
0.30% |
股份
|
| XTX Topco Ltd |
$630254 |
47819 |
0.30% |
股份
|
| CITADEL ADVISORS LLC |
$532340 |
40390 |
0.25% |
股份
|
| FMR LLC |
$513691 |
38975 |
0.24% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$472543 |
35853 |
0.22% |
股份
|
| D. E. Shaw & Co., Inc. |
$450927 |
34213 |
0.21% |
股份
|
| Jump Financial, LLC |
$446881 |
33906 |
0.21% |
股份
|
| Bank of New York Mellon Corp |
$418196 |
31730 |
0.20% |
股份
|
| AIHC Capital Management Ltd |
$398893 |
30265 |
0.19% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$383538 |
29100 |
0.18% |
买入期权
|
| Mariner, LLC |
$367824 |
27908 |
0.17% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$346028 |
26254 |
0.16% |
股份
|
| PANAGORA ASSET MANAGEMENT INC |
$337039 |
25572 |
0.16% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$317770 |
24110 |
0.15% |
股份
|
| MORGAN STANLEY |
$296563 |
22501 |
0.14% |
股份
|
| IEQ CAPITAL, LLC |
$280022 |
21246 |
0.13% |
股份
|
| MARSHALL WACE, LLP |
$251211 |
19060 |
0.12% |
股份
|
| GUGGENHEIM CAPITAL LLC |
$242512 |
18400 |
0.11% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$239876 |
18200 |
0.11% |
卖出期权
|
| HSBC HOLDINGS PLC |
$232803 |
17812 |
0.11% |
股份
|
| DEUTSCHE BANK AG\ |
$210194 |
15948 |
0.10% |
股份
|
| Nuveen, LLC |
$209048 |
15861 |
0.10% |
股份
|
| ALGERT GLOBAL LLC |
$187314 |
14212 |
0.09% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$177930 |
13500 |
0.08% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$169864 |
12888 |
0.08% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$167556 |
11508 |
0.08% |
股份
|
| RHUMBLINE ADVISERS |
$163435 |
12401 |
0.08% |
股份
|
| CITADEL ADVISORS LLC |
$163432 |
12400 |
0.08% |
卖出期权
|
| Trexquant Investment LP |
$151333 |
11482 |
0.07% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$150331 |
11406 |
0.07% |
股份
|
| Cerity Partners LLC |
$142264 |
10794 |
0.07% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$137878 |
12180 |
0.06% |
股份
|
| Engineers Gate Manager LP |
$134660 |
10217 |
0.06% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$133817 |
10153 |
0.06% |
股份
|
| WELLS FARGO & COMPANY/MN |
$126053 |
9564 |
0.06% |
股份
|
| CWM, LLC |
$110619 |
9772 |
0.05% |
股份
|
| TWO SIGMA ADVISERS, LP |
$90008 |
11237 |
0.04% |
股份
|
| Arax Advisory Partners |
$73742 |
5595 |
0.03% |
股份
|
| CITIGROUP INC |
$68128 |
5169 |
0.03% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$67613 |
5130 |
0.03% |
股份
|
| Russell Investments Group, Ltd. |
$65095 |
4939 |
0.03% |
股份
|
| AlphaQuest LLC |
$61701 |
7703 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$60984 |
4627 |
0.03% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$39540 |
3000 |
0.02% |
股份
|
| SIMPLEX TRADING, LLC |
$26030 |
1975 |
0.01% |
股份
|
| Vanguard Global Advisers, LLC |
$25424 |
1929 |
0.01% |
股份
|
| North Star Investment Management Corp. |
$23724 |
1800 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$20917 |
1587 |
0.01% |
股份
|
| Legal & General Group Plc |
$14261 |
1082 |
0.01% |
股份
|
| GAMMA Investing LLC |
$11348 |
861 |
0.01% |
股份
|
| TD Waterhouse Canada Inc. |
$11045 |
808 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$7882 |
598 |
0.00% |
股份
|
| Allworth Financial LP |
$7091 |
538 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$6564 |
498 |
0.00% |
股份
|
| DUNCKER STREETT & CO INC |
$5760 |
437 |
0.00% |
股份
|
| IFP Advisors, Inc |
$5509 |
418 |
0.00% |
股份
|
| Versant Capital Management, Inc |
$4826 |
487 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$4000 |
352 |
0.00% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$2547 |
225 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$2544 |
193 |
0.00% |
股份
|
| True Wealth Design, LLC |
$2531 |
192 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$2517 |
191 |
0.00% |
股份
|
| Essential Partners LLC |
$2372 |
180 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$1766 |
134 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$1621 |
123 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$1516 |
115 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$1226 |
93 |
0.00% |
股份
|
| Optiver Holding B.V. |
$791 |
60 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$461 |
35 |
0.00% |
股份
|
| Wealth Enhancement Trust Services, Inc. |
$435 |
33 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$383 |
29 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$264 |
20 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$252 |
19 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$233 |
17634 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$192 |
17 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$189 |
14480 |
0.00% |
股份
|
| JPL Wealth Management, LLC |
$40 |
3 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$13 |
1 |
0.00% |
股份
|