| VANGUARD GROUP INC |
$17031018 |
2677833 |
11.71% |
股份
|
| BlackRock, Inc. |
$15704976 |
3635411 |
10.80% |
股份
|
| Blue Water Life Science Advisors, LP |
$15008553 |
3474202 |
10.32% |
股份
|
| First Eagle Investment Management, LLC |
$11893673 |
2753165 |
8.18% |
股份
|
| Portolan Capital Management, LLC |
$8205011 |
1899308 |
5.64% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$7778782 |
1800644 |
5.35% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$5801782 |
1343005 |
3.99% |
股份
|
| Kent Lake PR LLC |
$5435430 |
1001000 |
3.74% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$4888805 |
1131377 |
3.36% |
股份
|
| AMERIPRISE FINANCIAL INC |
$4265671 |
987424 |
2.93% |
股份
|
| MARSHALL WACE, LLP |
$4207125 |
973872 |
2.89% |
股份
|
| STATE STREET CORP |
$4027566 |
932307 |
2.77% |
股份
|
| Tikvah Management LLC |
$2469118 |
571555 |
1.70% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$2114925 |
489566 |
1.45% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$2106432 |
487600 |
1.45% |
股份
|
| MORGAN STANLEY |
$1934013 |
447688 |
1.33% |
股份
|
| JANE STREET GROUP, LLC |
$1810296 |
419050 |
1.24% |
股份
|
| TUDOR INVESTMENT CORP ET AL |
$1729737 |
400402 |
1.19% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$1719314 |
397833 |
1.18% |
股份
|
| Cubist Systematic Strategies, LLC |
$1707290 |
314418 |
1.17% |
股份
|
| NORTHERN TRUST CORP |
$1456820 |
337227 |
1.00% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1342228 |
310701 |
0.92% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$1245504 |
288311 |
0.86% |
股份
|
| UBS Group AG |
$1218145 |
281978 |
0.84% |
股份
|
| Balyasny Asset Management L.P. |
$1123200 |
260000 |
0.77% |
买入期权
|
| Nuveen, LLC |
$1004798 |
232592 |
0.69% |
股份
|
| CITADEL ADVISORS LLC |
$992460 |
229736 |
0.68% |
股份
|
| XTX Topco Ltd |
$985111 |
228035 |
0.68% |
股份
|
| Point72 Asset Management, L.P. |
$974821 |
225653 |
0.67% |
股份
|
| GOLDMAN SACHS GROUP INC |
$916082 |
212056 |
0.63% |
股份
|
| FMR LLC |
$909940 |
210634 |
0.63% |
股份
|
| IRONWOOD INVESTMENT MANAGEMENT LLC |
$736798 |
170555 |
0.51% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$728439 |
168620 |
0.50% |
股份
|
| Invesco Ltd. |
$695032 |
160887 |
0.48% |
股份
|
| WELLS FARGO & COMPANY/MN |
$644362 |
149158 |
0.44% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$642030 |
148618 |
0.44% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$591304 |
136876 |
0.41% |
股份
|
| Bank of New York Mellon Corp |
$569808 |
131900 |
0.39% |
股份
|
| TWO SIGMA ADVISERS, LP |
$552620 |
86890 |
0.38% |
股份
|
| SCS Capital Management LLC |
$518551 |
120035 |
0.36% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$434000 |
100463 |
0.30% |
股份
|
| JNB Advisors LLC |
$432250 |
65000 |
0.30% |
股份
|
| Clarius Group, LLC |
$404011 |
62060 |
0.28% |
股份
|
| Quadrature Capital Ltd |
$346464 |
80200 |
0.24% |
股份
|
| Cerity Partners LLC |
$337319 |
78083 |
0.23% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$294736 |
68226 |
0.20% |
股份
|
| Clearstead Advisors, LLC |
$268969 |
62261 |
0.18% |
股份
|
| Jain Global LLC |
$247618 |
57319 |
0.17% |
股份
|
| ALGERT GLOBAL LLC |
$238537 |
55217 |
0.16% |
股份
|
| RHUMBLINE ADVISERS |
$231358 |
53557 |
0.16% |
股份
|
| PEDDOCK CAPITAL ADVISORS, LLC |
$225094 |
52105 |
0.15% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$199866 |
56780 |
0.14% |
股份
|
| Nebula Research & Development LLC |
$193814 |
29145 |
0.13% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$175660 |
40662 |
0.12% |
股份
|
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC |
$168312 |
38961 |
0.12% |
股份
|
| CANADA PENSION PLAN INVESTMENT BOARD |
$164592 |
38100 |
0.11% |
股份
|
| Russell Investments Group, Ltd. |
$162958 |
37722 |
0.11% |
股份
|
| DEUTSCHE BANK AG\ |
$158449 |
36678 |
0.11% |
股份
|
| IEQ CAPITAL, LLC |
$153390 |
35507 |
0.11% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$126516 |
29286 |
0.09% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$111158 |
25731 |
0.08% |
股份
|
| AXQ CAPITAL, LP |
$110588 |
25599 |
0.08% |
股份
|
| MetLife Investment Management, LLC |
$107140 |
24801 |
0.07% |
股份
|
| Aigen Investment Management, LP |
$105097 |
24328 |
0.07% |
股份
|
| OSAIC HOLDINGS, INC. |
$104438 |
24176 |
0.07% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$104426 |
26914 |
0.07% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$94176 |
21800 |
0.06% |
买入期权
|
| Dynamic Technology Lab Private Ltd |
$90000 |
20816 |
0.06% |
股份
|
| LPL Financial LLC |
$86828 |
20099 |
0.06% |
股份
|
| JPMORGAN CHASE & CO |
$86483 |
19049 |
0.06% |
股份
|
| CITIGROUP INC |
$85160 |
19713 |
0.06% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$84910 |
19655 |
0.06% |
股份
|
| Creative Planning |
$80084 |
18538 |
0.06% |
股份
|
| Vanguard Global Advisers, LLC |
$80028 |
18525 |
0.06% |
股份
|
| D. E. Shaw & Co., Inc. |
$76343 |
17672 |
0.05% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$74978 |
17356 |
0.05% |
股份
|
| BARCLAYS PLC |
$68278 |
15805 |
0.05% |
股份
|
| HUB Investment Partners, LLC |
$67971 |
15734 |
0.05% |
股份
|
| Mariner, LLC |
$66782 |
15471 |
0.05% |
股份
|
| Engineers Gate Manager LP |
$63966 |
14807 |
0.04% |
股份
|
| Jump Financial, LLC |
$63504 |
14700 |
0.04% |
股份
|
| CAPTRUST FINANCIAL ADVISORS |
$61780 |
14301 |
0.04% |
股份
|
| JANE STREET GROUP, LLC |
$61776 |
14300 |
0.04% |
买入期权
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$59564 |
13788 |
0.04% |
股份
|
| HighTower Advisors, LLC |
$59011 |
13660 |
0.04% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$57192 |
13239 |
0.04% |
股份
|
| PharVision Advisers, LLC |
$56328 |
13039 |
0.04% |
股份
|
| Schonfeld Strategic Advisors LLC |
$54702 |
12663 |
0.04% |
股份
|
| Post Resch Tallon Group Inc. |
$54000 |
12500 |
0.04% |
股份
|
| Qube Research & Technologies Ltd |
$51784 |
11987 |
0.04% |
股份
|
| KESTRA PRIVATE WEALTH SERVICES, LLC |
$48790 |
11294 |
0.03% |
股份
|
| IMC-Chicago, LLC |
$44124 |
10214 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$43468 |
10062 |
0.03% |
股份
|
| Cresset Asset Management, LLC |
$43200 |
10000 |
0.03% |
股份
|
| Arax Advisory Partners |
$32651 |
7558 |
0.02% |
股份
|
| SIMPLEX TRADING, LLC |
$30788 |
7127 |
0.02% |
股份
|
| PNC Financial Services Group, Inc. |
$30771 |
7123 |
0.02% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$28084 |
6501 |
0.02% |
股份
|
| CWM, LLC |
$26844 |
7626 |
0.02% |
股份
|
| Legal & General Group Plc |
$17270 |
3993 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$15012 |
3475 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$13427 |
3108 |
0.01% |
股份
|
| Sachetta, LLC |
$12960 |
3000 |
0.01% |
股份
|
| Allworth Financial LP |
$9258 |
2143 |
0.01% |
股份
|
| GROUP ONE TRADING LLC |
$8351 |
1933 |
0.01% |
股份
|
| Pinnacle Wealth Planning Services, Inc. |
$7772 |
1799 |
0.01% |
股份
|
| ROYAL BANK OF CANADA |
$7000 |
1475 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$6492 |
1503 |
0.00% |
股份
|
| True Wealth Design, LLC |
$4614 |
1068 |
0.00% |
股份
|
| NewEdge Advisors, LLC |
$4320 |
1000 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$3715 |
860 |
0.00% |
股份
|
| Wilmington Savings Fund Society, FSB |
$3456 |
800 |
0.00% |
股份
|
| Essential Partners LLC |
$2765 |
640 |
0.00% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$2714 |
771 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$2592 |
600 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$2527 |
585 |
0.00% |
股份
|
| Pinnacle Bancorp, Inc. |
$2246 |
520 |
0.00% |
股份
|
| AlphaQuest LLC |
$2137 |
336 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$1772 |
410252 |
0.00% |
股份
|
| GAMMA Investing LLC |
$1292 |
299 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$1078 |
249 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$894 |
207 |
0.00% |
股份
|
| US BANCORP \DE\ |
$873 |
202 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$868 |
201 |
0.00% |
股份
|
| Physician Wealth Advisors, Inc. |
$856 |
198 |
0.00% |
股份
|
| Bare Financial Services, Inc |
$795 |
184 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$756 |
175 |
0.00% |
股份
|
| Wealth Enhancement Trust Services, Inc. |
$696 |
161 |
0.00% |
股份
|
| Bogart Wealth, LLC |
$674 |
156 |
0.00% |
股份
|
| Ritter Daniher Financial Advisory LLC / DE |
$648 |
150 |
0.00% |
股份
|
| Point72 (DIFC) Ltd |
$646 |
119 |
0.00% |
股份
|
| Optiver Holding B.V. |
$436 |
101 |
0.00% |
股份
|
| Concord Wealth Partners |
$432 |
100 |
0.00% |
股份
|
| North Star Investment Management Corp. |
$432 |
100 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$414 |
95626 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$315 |
73 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$268 |
62 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$260 |
60 |
0.00% |
股份
|
| Cypress Capital Management LLC (WY) |
$259 |
60 |
0.00% |
股份
|
| HUNTINGTON NATIONAL BANK |
$168 |
39 |
0.00% |
股份
|
| Transamerica Financial Advisors, LLC |
$168 |
39 |
0.00% |
股份
|
| STRS OHIO |
$125 |
29 |
0.00% |
股份
|
| SIT INVESTMENT ASSOCIATES INC |
$1 |
272 |
0.00% |
股份
|
| Avion Wealth |
$0 |
198 |
0.00% |
股份
|