TSHA — الملاك المؤسسيون (13F)
المؤسسات التي تبلغ عن حيازتها لهذا السهم في نموذج SEC 13F ربع السنوي الخاص بها. المراكز الطويلة فقط؛ قد يظهر مقدم واحد مرتين لأرجل خيارات منفصلة. الأرجل الكبيرة المتعاكسة من خيارات البيع/الشراء تعكس عادةً صناعة السوق أو المخزون المتحوط، وليس القناعة الاتجاهية.
| مؤسسة | القيمة | الأسهم | % من 13F المتتبعة | النوع |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $162683327 | 23888888 | 7,59% | الأسهم |
| RA CAPITAL MANAGEMENT, L.P. | $160413963 | 23555648 | 7,48% | الأسهم |
| GOLDMAN SACHS GROUP INC | $154676334 | 22713118 | 7,21% | الأسهم |
| BlackRock, Inc. | $140912023 | 20691927 | 6,57% | الأسهم |
| Vestal Point Capital, LP | $132216150 | 19415000 | 6,17% | الأسهم |
| MORGAN STANLEY | $112279731 | 16487479 | 5,24% | الأسهم |
| RTW INVESTMENTS, LP | $92345357 | 13560258 | 4,31% | الأسهم |
| FMR LLC | $90820969 | 13336413 | 4,24% | الأسهم |
| VANGUARD CAPITAL MANAGEMENT LLC | $84979232 | 12478595 | 3,96% | الأسهم |
| STATE STREET CORP | $77783275 | 11421920 | 3,63% | الأسهم |
| VANGUARD GROUP INC | $72972929 | 13267805 | 3,40% | الأسهم |
| Siren, L.L.C. | $67055203 | 9846579 | 3,13% | الأسهم |
| Octagon Capital Advisors LP | $66010992 | 9693244 | 3,08% | الأسهم |
| GEODE CAPITAL MANAGEMENT, LLC | $44685322 | 6560394 | 2,08% | الأسهم |
| Polar Capital Holdings Plc | $34847676 | 5117133 | 1,63% | الأسهم |
| MPM BIOIMPACT LLC | $30645000 | 4500000 | 1,43% | الأسهم |
| D. E. Shaw & Co., Inc. | $29954821 | 4398652 | 1,40% | الأسهم |
| BAKER BROS. ADVISORS LP | $27272388 | 4004756 | 1,27% | الأسهم |
| WELLINGTON MANAGEMENT GROUP LLP | $27073870 | 3975605 | 1,26% | الأسهم |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $26460262 | 3885501 | 1,23% | الأسهم |
| GordonMD Global Investments LP | $24501508 | 723185 | 1,14% | الأسهم |
| Casdin Capital, LLC | $22132500 | 3250000 | 1,03% | الأسهم |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $21383461 | 3140009 | 1,00% | الأسهم |
| ADAR1 Capital Management, LLC | $20705573 | 3040466 | 0,97% | الأسهم |
| Pictet Asset Management Holding SA | $18868474 | 2770701 | 0,88% | الأسهم |
| Aberdeen Group plc | $15847905 | 2327152 | 0,74% | الأسهم |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | $15322500 | 2250000 | 0,71% | الأسهم |
| NORGES BANK | $15210816 | 2233600 | 0,71% | الأسهم |
| NORTHERN TRUST CORP | $15160491 | 2226210 | 0,71% | الأسهم |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14986733 | 2200695 | 0,70% | الأسهم |
| MILLENNIUM MANAGEMENT LLC | $14483767 | 2126838 | 0,68% | الأسهم |
| ORBIMED ADVISORS LLC | $13620000 | 2000000 | 0,64% | الأسهم |
| RICE HALL JAMES & ASSOCIATES, LLC | $13567079 | 1992229 | 0,63% | الأسهم |
| VANGUARD FIDUCIARY TRUST CO | $12914988 | 1896474 | 0,60% | الأسهم |
| B Group, Inc. | $12261786 | 1800556 | 0,57% | الأسهم |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | $12099000 | 3700000 | 0,56% | الأسهم |
| Affinity Asset Advisors, LLC | $11917500 | 1750000 | 0,56% | الأسهم |
| BARCLAYS PLC | $11104787 | 1630659 | 0,52% | الأسهم |
| CITADEL ADVISORS LLC | $10455305 | 1535287 | 0,49% | الأسهم |
| HEIGHTS CAPITAL MANAGEMENT, INC | $10215000 | 1500000 | 0,48% | الأسهم |
| Seven Fleet Capital Management LP | $9940323 | 1504400 | 0,46% | الأسهم |
| Palo Alto Investors LP | $9475311 | 1391382 | 0,44% | الأسهم |
| BANK OF AMERICA CORP /DE/ | $9349074 | 1372845 | 0,44% | الأسهم |
| Granahan Investment Management, LLC | $8888255 | 1305177 | 0,41% | الأسهم |
| Quantum Private Wealth, LLC | $5529903 | 812027 | 0,26% | الأسهم |
| FIRST TRUST ADVISORS LP | $5387860 | 791169 | 0,25% | الأسهم |
| JPMORGAN CHASE & CO | $5157078 | 766282 | 0,24% | الأسهم |
| Sands Capital Alternatives, LLC | $4936385 | 724873 | 0,23% | الأسهم |
| Bank of New York Mellon Corp | $4753180 | 697971 | 0,22% | الأسهم |
| BNP PARIBAS FINANCIAL MARKETS | $4358638 | 640035 | 0,20% | الأسهم |
| PANAGORA ASSET MANAGEMENT INC | $4020535 | 590387 | 0,19% | الأسهم |
| UBS Group AG | $4007188 | 588427 | 0,19% | الأسهم |
| AFFINITY WEALTH MANAGEMENT LLC | $3928062 | 576808 | 0,18% | الأسهم |
| Squarepoint Ops LLC | $3876722 | 569269 | 0,18% | الأسهم |
| ACUTA CAPITAL PARTNERS, LLC | $3825912 | 561808 | 0,18% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3799980 | 558000 | 0,18% | عقد خيار الشراء |
| Nuveen, LLC | $3784270 | 555693 | 0,18% | الأسهم |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3765930 | 553000 | 0,18% | الأسهم |
| DIADEMA PARTNERS LP | $3559035 | 522619 | 0,17% | الأسهم |
| Woodline Partners LP | $3499169 | 513828 | 0,16% | الأسهم |
| Holocene Advisors, LP | $3473100 | 510000 | 0,16% | الأسهم |
| Ghisallo Capital Management LLC | $3439050 | 505000 | 0,16% | الأسهم |
| Burkehill Global Management, LP | $3405000 | 500000 | 0,16% | الأسهم |
| POLEN CAPITAL MANAGEMENT LLC | $3331581 | 489219 | 0,16% | الأسهم |
| DIMENSIONAL FUND ADVISORS LP | $3162863 | 464771 | 0,15% | الأسهم |
| VOYA INVESTMENT MANAGEMENT LLC | $2896723 | 425363 | 0,14% | الأسهم |
| Trexquant Investment LP | $2584919 | 379577 | 0,12% | الأسهم |
| Swiss National Bank | $2512890 | 369000 | 0,12% | الأسهم |
| MOORE CAPITAL MANAGEMENT, LP | $2440527 | 358374 | 0,11% | الأسهم |
| WELLS FARGO & COMPANY/MN | $2269869 | 333314 | 0,11% | الأسهم |
| Jefferies Financial Group Inc. | $2239128 | 328800 | 0,10% | الأسهم |
| CITIGROUP INC | $2090037 | 306907 | 0,10% | الأسهم |
| RHUMBLINE ADVISERS | $2042820 | 299975 | 0,10% | الأسهم |
| ALPS ADVISORS INC | $1978598 | 290543 | 0,09% | الأسهم |
| Invesco Ltd. | $1800421 | 264379 | 0,08% | الأسهم |
| Ensign Peak Advisors, Inc | $1790322 | 262896 | 0,08% | الأسهم |
| Qube Research & Technologies Ltd | $1767910 | 259605 | 0,08% | الأسهم |
| SPHERA FUNDS MANAGEMENT LTD. | $1702500 | 250000 | 0,08% | الأسهم |
| DEUTSCHE BANK AG\ | $1657411 | 243379 | 0,08% | الأسهم |
| TWO SIGMA INVESTMENTS, LP | $1598416 | 234716 | 0,07% | الأسهم |
| JANE STREET GROUP, LLC | $1555098 | 228355 | 0,07% | الأسهم |
| ORACLE INVESTMENT MANAGEMENT INC | $1457500 | 265000 | 0,07% | الأسهم |
| Monashee Investment Management LLC | $1362000 | 200000 | 0,06% | الأسهم |
| Privium Fund Management B.V. | $1354509 | 198900 | 0,06% | الأسهم |
| VICTORY CAPITAL MANAGEMENT INC | $1345506 | 197578 | 0,06% | الأسهم |
| Chicago Partners Investment Group LLC | $1296283 | 222347 | 0,06% | الأسهم |
| Balyasny Asset Management L.P. | $1289351 | 189332 | 0,06% | الأسهم |
| STATE OF WISCONSIN INVESTMENT BOARD | $1205976 | 177089 | 0,06% | الأسهم |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1188104 | 265795 | 0,06% | الأسهم |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1153437 | 169374 | 0,05% | الأسهم |
| RAYMOND JAMES FINANCIAL INC | $1130746 | 166042 | 0,05% | الأسهم |
| ALLIANCEBERNSTEIN L.P. | $1107130 | 247680 | 0,05% | الأسهم |
| WEXFORD CAPITAL LP | $1094054 | 160654 | 0,05% | الأسهم |
| Rafferty Asset Management, LLC | $1053548 | 154706 | 0,05% | الأسهم |
| Palumbo Wealth Management LLC | $1015869 | 149173 | 0,05% | الأسهم |
| MetLife Investment Management, LLC | $959161 | 140846 | 0,04% | الأسهم |
| Vanguard Global Advisers, LLC | $911321 | 133821 | 0,04% | الأسهم |
| Persistent Asset Partners Ltd | $908529 | 133411 | 0,04% | الأسهم |
| VANGUARD ASSET MANAGEMENT, Ltd | $903101 | 132614 | 0,04% | الأسهم |
| AQR CAPITAL MANAGEMENT LLC | $876883 | 128764 | 0,04% | الأسهم |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $869664 | 127915 | 0,04% | الأسهم |
| Mariner, LLC | $793923 | 116582 | 0,04% | الأسهم |
| CITADEL ADVISORS LLC | $783150 | 115000 | 0,04% | عقد خيار الشراء |
| TWO SIGMA ADVISERS, LP | $767696 | 139581 | 0,04% | الأسهم |
| Aquatic Capital Management LLC | $736896 | 108208 | 0,03% | الأسهم |
| Legal & General Group Plc | $736890 | 108207 | 0,03% | الأسهم |
| FRANKLIN RESOURCES INC | $723835 | 106290 | 0,03% | الأسهم |
| Engineers Gate Manager LP | $709139 | 104132 | 0,03% | الأسهم |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $708887 | 104095 | 0,03% | الأسهم |
| XTX Topco Ltd | $689138 | 101195 | 0,03% | الأسهم |
| PRELUDE CAPITAL MANAGEMENT, LLC | $669736 | 98346 | 0,03% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $663294 | 97400 | 0,03% | عقد خيار البيع |
| PROFUND ADVISORS LLC | $546162 | 80200 | 0,03% | الأسهم |
| Police & Firemen's Retirement System of New Jersey | $481596 | 70719 | 0,02% | الأسهم |
| NEW YORK STATE COMMON RETIREMENT FUND | $471933 | 69300 | 0,02% | الأسهم |
| J. Goldman & Co LP | $458647 | 67349 | 0,02% | الأسهم |
| RED REEF ADVISORS LLC | $449120 | 65950 | 0,02% | الأسهم |
| China Universal Asset Management Co., Ltd. | $447649 | 65734 | 0,02% | الأسهم |
| Creative Planning | $434349 | 63781 | 0,02% | الأسهم |
| CITADEL ADVISORS LLC | $428349 | 62900 | 0,02% | عقد خيار البيع |
| COMMONWEALTH EQUITY SERVICES, LLC | $420678 | 61773 | 0,02% | الأسهم |
| Russell Investments Group, Ltd. | $420210 | 61705 | 0,02% | الأسهم |
| OMERS ADMINISTRATION Corp | $402471 | 59100 | 0,02% | الأسهم |
| Virtus Investment Advisers, LLC | $390233 | 57303 | 0,02% | الأسهم |
| LANARK FINANCIAL, INC. | $374699 | 55022 | 0,02% | الأسهم |
| INTECH INVESTMENT MANAGEMENT LLC | $358329 | 52618 | 0,02% | الأسهم |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $335141 | 49213 | 0,02% | الأسهم |
| KLP KAPITALFORVALTNING AS | $325518 | 47800 | 0,02% | الأسهم |
| Militia Capital Management LLC | $316665 | 46500 | 0,01% | الأسهم |
| State of New Jersey Common Pension Fund D | $316277 | 46443 | 0,01% | الأسهم |
| JANUS HENDERSON GROUP PLC | $308085 | 69000 | 0,01% | الأسهم |
| Williams & Novak, LLC | $306450 | 45000 | 0,01% | الأسهم |
| Almanack Investment Partners, LLC. | $306110 | 44950 | 0,01% | الأسهم |
| FIRST MANHATTAN CO. LLC. | $296235 | 43500 | 0,01% | الأسهم |
| Mitsubishi UFJ Asset Management Co., Ltd. | $294131 | 43191 | 0,01% | الأسهم |
| Allianz Asset Management GmbH | $288744 | 42400 | 0,01% | الأسهم |
| ProShare Advisors LLC | $277965 | 40817 | 0,01% | الأسهم |
| ARIZONA STATE RETIREMENT SYSTEM | $269901 | 39633 | 0,01% | الأسهم |
| PRUDENTIAL FINANCIAL INC | $265862 | 39040 | 0,01% | الأسهم |
| JANE STREET GROUP, LLC | $260142 | 38200 | 0,01% | عقد خيار الشراء |
| Militia Capital Partners, LP | $255750 | 46500 | 0,01% | الأسهم |
| ENVESTNET ASSET MANAGEMENT INC | $254108 | 37314 | 0,01% | الأسهم |
| Vanguard Investments Australia, Ltd. | $244390 | 35887 | 0,01% | الأسهم |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $218935 | 32149 | 0,01% | الأسهم |
| Cetera Investment Advisers | $215244 | 31607 | 0,01% | الأسهم |
| GUGGENHEIM CAPITAL LLC | $202401 | 29721 | 0,01% | الأسهم |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $184987 | 27164 | 0,01% | الأسهم |
| Quadrature Capital Ltd | $175378 | 25753 | 0,01% | الأسهم |
| nVerses Capital, LLC | $171285 | 25152 | 0,01% | الأسهم |
| State of Wyoming | $166041 | 24382 | 0,01% | الأسهم |
| XPONANCE LLC | $155820 | 22881 | 0,01% | الأسهم |
| E Fund Management Co., Ltd. | $148553 | 21814 | 0,01% | الأسهم |
| Ameritas Investment Partners, Inc. | $148192 | 21761 | 0,01% | الأسهم |
| Lee Financial Co | $136200 | 20000 | 0,01% | الأسهم |
| ALLSTATE CORP | $132434 | 19447 | 0,01% | الأسهم |
| Weiss Asset Management LP | $130371 | 19144 | 0,01% | الأسهم |
| Aster Capital Management (DIFC) Ltd | $126346 | 18553 | 0,01% | الأسهم |
| PRINCIPAL FINANCIAL GROUP INC | $124855 | 18334 | 0,01% | الأسهم |
| Vanguard Personalized Indexing Management, LLC | $122437 | 17979 | 0,01% | الأسهم |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $113972 | 16736 | 0,01% | الأسهم |
| ST GERMAIN D J CO INC | $96246 | 14133 | 0,00% | الأسهم |
| SEI INVESTMENTS CO | $95004 | 13952 | 0,00% | الأسهم |
| BANK OF MONTREAL /CAN/ | $93079 | 13668 | 0,00% | الأسهم |
| CAPTRUST FINANCIAL ADVISORS | $91629 | 13455 | 0,00% | الأسهم |
| SIMPLEX TRADING, LLC | $91056 | 13371 | 0,00% | الأسهم |
| CIBC Bancorp USA Inc. | $90315 | 13262 | 0,00% | الأسهم |
| Mirae Asset Global Investments Co., Ltd. | $87522 | 12852 | 0,00% | الأسهم |
| Ethic Inc. | $85207 | 12512 | 0,00% | الأسهم |
| CIBC WORLD MARKETS CORP | $80366 | 14612 | 0,00% | الأسهم |
| Tower Research Capital LLC (TRC) | $78519 | 11530 | 0,00% | الأسهم |
| Magnetar Financial LLC | $78145 | 11475 | 0,00% | الأسهم |
| NEUBERGER BERMAN GROUP LLC | $76068 | 11170 | 0,00% | الأسهم |
| Summit Financial, LLC | $74147 | 10888 | 0,00% | الأسهم |
| CHOREO, LLC | $72309 | 10618 | 0,00% | الأسهم |
| Capital Investment Advisors, LLC | $68100 | 10000 | 0,00% | الأسهم |
| OSAIC HOLDINGS, INC. | $60191 | 8838 | 0,00% | الأسهم |
| CWM, LLC | $58472 | 13081 | 0,00% | الأسهم |
| ROYAL BANK OF CANADA | $51000 | 7386 | 0,00% | الأسهم |
| Allworth Financial LP | $47521 | 6978 | 0,00% | الأسهم |
| GF FUND MANAGEMENT CO. LTD. | $39478 | 5797 | 0,00% | الأسهم |
| NISA INVESTMENT ADVISORS, LLC | $39362 | 5780 | 0,00% | الأسهم |
| Rockefeller Capital Management L.P. | $34050 | 5000 | 0,00% | الأسهم |
| Bordeaux Wealth Advisors LLC | $23234 | 10058 | 0,00% | الأسهم |
| SBI Securities Co., Ltd. | $20873 | 3065 | 0,00% | الأسهم |
| Steward Partners Investment Advisory, LLC | $20430 | 3000 | 0,00% | الأسهم |
| Kemnay Advisory Services Inc. | $17583 | 2582 | 0,00% | الأسهم |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $14294 | 2099 | 0,00% | الأسهم |
| Chung Wu Investment Group, LLC | $13620 | 2000 | 0,00% | الأسهم |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | $13300 | 2000 | 0,00% | الأسهم |
| GROUP ONE TRADING LLC | $13205 | 1939 | 0,00% | الأسهم |
| Caitong International Asset Management Co., Ltd | $12633 | 1855 | 0,00% | الأسهم |
| JONES FINANCIAL COMPANIES LLLP | $9263 | 1461 | 0,00% | الأسهم |
| US BANCORP \DE\ | $7845 | 1152 | 0,00% | الأسهم |
| PNC Financial Services Group, Inc. | $7171 | 1053 | 0,00% | الأسهم |
| Sterling Capital Management LLC | $5734 | 842 | 0,00% | الأسهم |
| Federation des caisses Desjardins du Quebec | $3405 | 500 | 0,00% | الأسهم |
| Quarry LP | $3269 | 480 | 0,00% | الأسهم |
| Larson Financial Group LLC | $3194 | 469 | 0,00% | الأسهم |
| Optiver Holding B.V. | $3017 | 443 | 0,00% | الأسهم |
| Arax Advisory Partners | $2451 | 360 | 0,00% | الأسهم |
| Essential Partners LLC | $2227 | 327 | 0,00% | الأسهم |
| Parallel Advisors, LLC | $1907 | 280 | 0,00% | الأسهم |
| SIGNATUREFD, LLC | $1811 | 266 | 0,00% | الأسهم |
| GAMMA Investing LLC | $1580 | 232 | 0,00% | الأسهم |
| SG Americas Securities, LLC | $1377 | 202260 | 0,00% | الأسهم |
| PRICE T ROWE ASSOCIATES INC /MD/ | $1359 | 199494 | 0,00% | الأسهم |
| ROTHSCHILD INVESTMENT LLC | $1158 | 170 | 0,00% | الأسهم |
| EverSource Wealth Advisors, LLC | $960 | 141 | 0,00% | الأسهم |
| Lindbrook Capital, LLC | $605 | 435 | 0,00% | الأسهم |
| NATIONAL BANK OF CANADA /FI/ | $578 | 85 | 0,00% | الأسهم |
| GSA CAPITAL PARTNERS LLP | $494 | 72573 | 0,00% | الأسهم |
| Farther Finance Advisors, LLC | $375 | 55 | 0,00% | الأسهم |
| True Wealth Design, LLC | $205 | 30 | 0,00% | الأسهم |
| Keating Financial Advisory Services, Inc. | $177 | 26 | 0,00% | الأسهم |
| Cambridge Investment Research Advisors, Inc. | $103 | 15075 | 0,00% | الأسهم |
| Thrivent Financial for Lutherans | $98 | 14520 | 0,00% | الأسهم |
| IFP Advisors, Inc | $95 | 14 | 0,00% | الأسهم |
| Hughes Financial Services, LLC | $41 | 6 | 0,00% | الأسهم |
| Pacer Advisors, Inc. | $18 | 2584 | 0,00% | الأسهم |
| Covestor Ltd | $1 | 94 | 0,00% | الأسهم |
| Capital Advisors, Ltd. LLC | $1 | 79 | 0,00% | الأسهم |