SEPN Septerna, Inc. - Common Stock
$44,27
Kurs · Aug 18, 2026
Fundamentaldaten per Aug 10, 2026
52W-Spanne
$11–$51
83% of range
Analystenbewertung
BUY
16 analysts
Kursziel
$53
+20% upside
P/E (TTM)
-40.2
ROE
-12.9%
Nettogewinnmarge
-106.4%
SEPN Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne
Kurs
$44.27
Marktkapitalisierung
$1.98B
P/E (TTM)
-40.2
EPS (TTM)
$-1.10
Umsatz (TTM)
$46M
Dividendenrendite
—
ROE
-12.9%
Verschuldungsgrad
—
52W-Spanne
$11 – $51
SEPN Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen
Configure
10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends
Umsatz & Nettoergebnis
$46M
2023-12-31
→
2025-12-31
EPS
$-1.10
2023-12-31
→
2025-12-31
Freier Cashflow
$110M
2024-12-31
→
2025-12-31
Margen
-106.4%
Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?
Kennzahl
5-Jahres-Trend
SEPN
Peer-Median
P/E (TTM)
-40.2
19.1
P/S (TTM) (K/V (TTM))
43.2
14.2
P/B (K/B)
5.2
3.6
Price / FCF (Kurs / FCF)
18.1
—
Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC
Kennzahl
5-Jahres-Trend
SEPN
Peer-Median
Operating Margin (Betriebsgewinnmarge)
-148.6%
—
Net Profit Margin (Nettogewinnmarge)
-106.4%
-4.3%
ROA
-9.3%
-2.9%
ROE
-12.9%
-6.8%
ROIC
-17.9%
—
Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke
Kennzahl
5-Jahres-Trend
SEPN
Peer-Median
Current Ratio (Liquiditätsgrad)
4.7
4.7
Quick Ratio
4.6
—
Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR
Kennzahl
5-Jahres-Trend
SEPN
Peer-Median
Revenue YoY (Umsatz YoY)
4174.5%
—
Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag
Kennzahl
5-Jahres-Trend
SEPN
Peer-Median
SEPN Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial
KAUF
16 Analysten
- Starker Kauf 5 31,2%
- Kauf 10 62,5%
- Halten 1 6,2%
- Verkauf 0 0,0%
- Starker Verkauf 0 0,0%
12-Monats-Kursziel
9 Analysten · 2026-08-17
Median
$51.00
Mittelwert
$53.11
Jetzt
$44.27
Tief
$38.00
Hoch
$62.00
Median-Ziel
$51.00
+15,2%
Mittelwert-Ziel
$53.11
+20,0%
Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum
Durchschn. Überraschung
-0.33%
| Zeitraum | EPS Actual | EPS est. | Überraschung |
|---|---|---|---|
| 30. Juni 2026 | $-0.29 | $-0.43 | 0.14% |
| 31. März 2026 | $-0.19 | $-0.42 | 0.23% |
| 31. Dezember 2025 | $-0.24 | $-0.26 | 0.02% |
| 30. September 2025 | $-0.09 | $0.81 | -0.90% |
| 30. Juni 2025 | $-0.56 | $0.88 | -1.4% |
| 31. März 2025 | $-0.49 | $-0.46 | -0.03% |
Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen
| Ticker | Marktkapitalisierung | P/E | Umsatz Vj. | Nettomarge | ROE | Bruttogewinnmarge |
|---|---|---|---|---|---|---|
| SEPN | $1.25B | -25.3 | 4174.5% | -106.4% | -12.9% | — |
| RAPP | $1.45B | -10.6 | — | — | -29.8% | — |
| OCUL | $2.62B | -8.5 | -18.5% | -511.9% | -55.4% | — |
| NUVB | $3.03B | -14.9 | 699.0% | -325.3% | -60.3% | — |
| HRMY | $2.16B | 13.8 | 21.5% | 18.3% | 19.3% | 77.2% |
| KARD | — | — | — | — | — | — |
| TRLV | — | — | -0.45% | -10.3% | -10.4% | 60.2% |
| ANIP | $1.78B | 23.8 | 43.8% | 8.9% | 16.6% | — |
| ETON | $457M | — | 104.9% | -5.8% | -18.4% | 53.5% |
| AVLN | — | — | — | — | — | — |
Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow
Gewinn- und Verlustrechnung 15
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $46M | $1M | $151.0K | |
| R&D Expense | $98M | $65M | $36M | |
| SG&A Expense | $29M | $17M | $10M | |
| Operating Expenses | $114M | $82M | $-2M | |
| Operating Income | $-68M | $-81M | $2M | |
| Interest Income | $20M | $9M | $3M | |
| Other Non-op | $-100.0K | $-90.0K | $10.0K | |
| Pretax Income | $-49M | $-72M | $-49M | |
| Income Tax | $12.0K | $-498.0K | $691.0K | |
| Net Income | $-49M | $-72M | $4M | |
| EPS (Basic) | $-1.10 | $-7.26 | $0.29 | |
| EPS (Diluted) | $-1.10 | $-7.26 | $0.29 | |
| Shares (Basic) | 44,258,338 | 9,891,126 | 1,928,586 | |
| Shares (Diluted) | 44,258,338 | 9,891,126 | 2,177,124 | |
| EBITDA | $-67M | $-79M | · |
Bilanz 23
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $121M | $238M | $88M | |
| Short-term Investments | $270M | $113M | $0 | |
| Receivables | $10M | $171.0K | $151.0K | |
| Prepaid Expense | $10M | $6M | $1M | |
| Other Current Assets | $1M | $239.0K | $92.0K | |
| Current Assets | $411M | $357M | $113M | |
| PP&E (Net) | $4M | $5M | $5M | |
| PP&E (Gross) | $9M | $8M | $6M | |
| Accum. Depreciation | $4M | $3M | $2M | |
| Other Non-current Assets | $816.0K | $267.0K | $97.0K | |
| Total Assets | $596M | $457M | $131M | |
| Accounts Payable | $10M | $3M | $3M | |
| Accrued Liabilities | $12M | $8M | $4M | |
| Current Liabilities | $87M | $13M | $7M | |
| Capital Leases | $21M | $24M | $13M | |
| Other Non-current Liabilities | $0 | $33.0K | $546.0K | |
| Total Liabilities | $214M | $37M | $20M | |
| Common Stock | $45.0K | $44.0K | $3.0K | |
| Retained Earnings | $-167M | $-118M | $-47M | |
| AOCI | $617.0K | $56.0K | $0 | |
| Stockholders' Equity | $382M | $420M | $-38M | |
| Liabilities + Equity | $596M | $457M | $131M | |
| Shares Outstanding | 44,806,272 | 44,422,505 | 3,168,134 |
Cashflow 11
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | $2M | $1M | $800.0K | |
| Stock-based Comp | $8M | $3M | $2M | |
| Deferred Tax | $0 | $-491.0K | $491.0K | |
| Other Non-cash | $149M | $267.0K | · | |
| Operating Cash Flow | $110M | $-67M | $-39M | |
| CapEx | $518.0K | $2M | $3M | |
| Investing Cash Flow | $-229M | $-161M | $22M | |
| Financing Cash Flow | $2M | $378M | $75M | |
| Net Change in Cash | $-117M | $150M | $58M | |
| Taxes Paid | $0 | $232.0K | $75.0K | |
| Free Cash Flow | $110M | $-70M | · |
Rentabilität 7
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -148.6% | -7518.4% | · | |
| Net Margin | -106.4% | -6678.9% | · | |
| Pretax Margin | -106.3% | -6725.2% | · | |
| EBITDA Margin | -145.2% | -7388.2% | · | |
| ROA | -9.3% | -24.4% | · | |
| ROE | -12.9% | -43.2% | · | |
| ROIC | -17.9% | -19.1% | · |
Liquidität & Solvenz 2
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 4.7 | 27.8 | · | |
| Quick Ratio | 4.6 | 27.3 | · |
Effizienz 2
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.0 | · | |
| Receivables Turnover | 8.7 | 6.7 | · |
Wachstumsraten 1
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | 4174.5% | 611.9% | · |
Bewertung (TTM) 10
| Kennzahl | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $46M | $1M | · | |
| Net Income TTM | $-49M | $-72M | · | |
| Market Cap | $1.25B | $1.02B | · | |
| P/E | -25.3 | -3.2 | · | |
| P/S | 27.2 | 946.3 | · | |
| P/B | 3.3 | 2.4 | · | |
| P / Tangible Book | 3.3 | 2.4 | · | |
| P / Cash Flow | 11.3 | -15.1 | · | |
| P / FCF | 11.4 | -14.6 | · | |
| Earnings Yield | -4.0% | -31.7% | · |
Gewinn- und Verlustrechnung 15
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $27M | $27M | $24M | $21M | $119.0K | $219.0K | $212.0K | $176.0K | $370.0K | $317.0K | |
| R&D Expense | $35M | $30M | $32M | $24M | $22M | $19M | $19M | $18M | $15M | $13M | |
| SG&A Expense | $8M | $10M | $8M | $7M | $7M | $7M | $6M | $5M | $3M | $3M | |
| Operating Expenses | $44M | $40M | $40M | $19M | $29M | $26M | $25M | $23M | $18M | $16M | |
| Operating Income | $-17M | $-13M | $-16M | $3M | $-29M | $-26M | $-25M | $-23M | $-18M | $-15M | |
| Interest Income | $5M | $5M | $5M | $6M | $4M | $4M | $4M | $2M | $2M | $1M | |
| Other Non-op | $-23.0K | $-31.0K | $-41.0K | $-6.0K | $-25.0K | $-28.0K | $-18.0K | $-9.0K | $-15.0K | $-48.0K | |
| Pretax Income | $-12M | $-8M | $-11M | $8M | $-25M | $-21M | $-21M | $-21M | $-17M | $-14M | |
| Income Tax | $973.0K | $337.0K | $12.0K | $0 | $0 | $0 | $-564.0K | $-136.0K | $109.0K | $93.0K | |
| Net Income | $-13M | $-9M | $-11M | $8M | $-25M | $-21M | $-21M | $-21M | $-17M | $-14M | |
| EPS (Basic) | $-0.29 | $-0.19 | $-0.23 | $0.18 | $-0.56 | $-0.49 | $14.52 | $-8.40 | $-7.03 | $-6.35 | |
| EPS (Diluted) | $-0.29 | $-0.19 | $-0.23 | $0.18 | $-0.56 | $-0.49 | $14.52 | $-8.40 | $-7.03 | $-6.35 | |
| Shares (Basic) | 45,040,075 | 44,758,800 | -88,187,325 | 44,343,085 | 44,165,168 | 43,937,410 | 2,877,617 | 2,443,678 | 2,337,585 | 2,232,246 | |
| Shares (Diluted) | 45,040,075 | 44,758,800 | -89,446,339 | 45,602,099 | 44,165,168 | 43,937,410 | 2,877,617 | 2,443,678 | 2,337,585 | 2,232,246 | |
| EBITDA | $-16M | $-13M | · | $3M | $-29M | $-26M | · | $-22M | · | · |
Bilanz 23
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $85M | $72M | $121M | $320M | $189M | $210M | $238M | $88M | · | · | |
| Short-term Investments | $288M | $276M | $270M | $154M | $137M | $126M | $113M | $42M | · | · | |
| Receivables | $12M | $11M | $10M | $9M | $151.0K | $250.0K | $171.0K | $210.0K | · | · | |
| Prepaid Expense | $12M | $10M | $10M | $9M | $7M | $6M | $6M | $3M | · | · | |
| Other Current Assets | $133.0K | $110.0K | $1M | $387.0K | $0 | $52.0K | $239.0K | $241.0K | · | · | |
| Current Assets | $396M | $368M | $411M | $492M | $334M | $342M | $357M | $133M | · | · | |
| PP&E (Net) | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | · | · | |
| PP&E (Gross) | $9M | $9M | $9M | $8M | $8M | $8M | $8M | $8M | · | · | |
| Accum. Depreciation | $5M | $5M | $4M | $4M | $4M | $3M | $3M | $3M | · | · | |
| Other Non-current Assets | $1M | $773.0K | $816.0K | $501.0K | $300.0K | $277.0K | $267.0K | $3M | · | · | |
| Total Assets | $567M | $570M | $596M | $607M | $415M | $434M | $457M | $174M | · | · | |
| Accounts Payable | $4M | $7M | $10M | $4M | $7M | $4M | $3M | $6M | · | · | |
| Accrued Liabilities | $13M | $9M | $12M | $8M | $7M | $4M | $8M | $6M | · | · | |
| Current Liabilities | $79M | $78M | $87M | $75M | $15M | $11M | $13M | $13M | · | · | |
| Capital Leases | $20M | $21M | $21M | $22M | $23M | $23M | $24M | $24M | · | · | |
| Other Non-current Liabilities | $521.0K | $100.0K | $0 | $0 | $2.0K | $27.0K | $33.0K | $191.0K | · | · | |
| Total Liabilities | $180M | $191M | $214M | $218M | $38M | $34M | $37M | $38M | · | · | |
| Common Stock | $46.0K | $45.0K | $45.0K | $45.0K | $45.0K | $44.0K | $44.0K | $3.0K | · | · | |
| Retained Earnings | $-189M | $-176M | $-167M | $-157M | $-165M | $-140M | $-118M | $-98M | · | · | |
| AOCI | $-1M | $-569.0K | $617.0K | $375.0K | $176.0K | $198.0K | $56.0K | $176.0K | · | · | |
| Stockholders' Equity | $387M | $378M | $382M | $389M | $378M | $400M | $420M | $-87M | · | · | |
| Liabilities + Equity | $567M | $570M | $596M | $607M | $415M | $434M | $457M | $174M | · | · | |
| Shares Outstanding | 45,667,490 | 44,916,572 | 44,806,272 | 44,638,703 | 44,567,891 | 44,448,435 | 44,422,505 | · | · | · |
Cashflow 11
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $400.0K | $400.0K | $400.0K | $400.0K | $400.0K | $400.0K | $400.0K | $400.0K | $300.0K | $300.0K | |
| Stock-based Comp | $5M | $6M | $3M | $3M | $2M | $1M | $1M | $683.0K | $628.0K | $577.0K | |
| Deferred Tax | · | · | · | · | · | · | $-153.0K | $-136.0K | $-109.0K | $-93.0K | |
| Other Non-cash | · | $-23M | · | · | · | $-4M | · | · | · | · | |
| Operating Cash Flow | $-22M | $-26M | $-15M | $169M | $-20M | $-23M | $-21M | $-17M | $-13M | $-17M | |
| CapEx | $0 | $832.0K | $65.0K | $13.0K | $58.0K | $382.0K | $612.0K | $578.0K | $149.0K | $764.0K | |
| Investing Cash Flow | $18M | $-24M | $-185M | $-38M | $-786.0K | $-5M | $-133M | $-25M | $-12M | $10M | |
| Financing Cash Flow | $17M | $333.0K | $1M | $263.0K | $339.0K | $66.0K | $304M | $-1M | · | · | |
| Net Change in Cash | $13M | $-49M | $-199M | $131M | $-21M | $-28M | $150M | $-43M | $50M | $-7M | |
| Taxes Paid | · | · | · | · | · | · | $0 | $75.0K | · | · | |
| Free Cash Flow | · | $-26M | · | · | · | $-24M | · | · | · | · |
Rentabilität 7
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -62.9% | -50.1% | · | 12.2% | -24351.3% | -11831.1% | · | -12812.5% | · | · | |
| Net Margin | -48.7% | -32.6% | · | 38.0% | -20872.3% | -9806.4% | · | -11660.8% | · | · | |
| Pretax Margin | -45.1% | -31.3% | · | 38.0% | -20872.3% | -9806.4% | · | -11738.1% | · | · | |
| EBITDA Margin | -61.5% | -48.6% | · | 14.0% | -24015.1% | -11648.4% | · | -12585.2% | · | · | |
| ROA | -2.6% | -1.7% | · | 2.1% | -12.0% | -9.9% | · | -23.5% | · | · | |
| ROE | -3.4% | -2.2% | · | 5.4% | -13.2% | -10.7% | · | 47.0% | · | · | |
| ROIC | -4.7% | -3.7% | · | 0.67% | -7.7% | -6.5% | · | 25.6% | · | · |
Liquidität & Solvenz 2
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.0 | 4.7 | · | 6.5 | 22.1 | 32.2 | · | 10.1 | · | · | |
| Quick Ratio | 4.8 | 4.6 | · | 6.4 | 21.6 | 31.6 | · | 9.9 | · | · |
Effizienz 2
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.1 | · | 0.1 | 0.0 | 0.0 | · | 0.0 | · | · | |
| Receivables Turnover | 4.3 | 4.8 | · | 4.9 | 1.6 | 1.8 | · | 1.7 | · | · |
Bewertung (TTM) 10
| Kennzahl | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $75M | $48M | · | $22M | $884.0K | $1M | · | $896.0K | · | · | |
| Net Income TTM | $-38M | $-47M | · | $-59M | $-83M | $-73M | · | $-62M | · | · | |
| Market Cap | $1.53B | $1.08B | · | $840M | $471M | $257M | · | · | · | · | |
| P/E | -38.9 | -22.7 | · | -2.0 | -0.6 | -0.3 | · | · | · | · | |
| P/S | 20.4 | 22.3 | · | 38.2 | 532.9 | 237.9 | · | · | · | · | |
| P/B | 4.0 | 2.9 | · | 2.2 | 1.2 | 0.6 | · | · | · | · | |
| P / Tangible Book | 4.0 | 2.9 | · | 2.2 | 1.2 | 0.6 | · | · | · | · | |
| P / Cash Flow | · | -42.1 | · | · | · | -11.0 | · | · | · | · | |
| P / FCF | · | -40.8 | · | · | · | -10.8 | · | · | · | · | |
| Earnings Yield | -2.6% | -4.4% | · | -49.3% | -155.9% | -384.6% | · | · | · | · |
Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre
Gewinn- und Verlustrechnung
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Umsatz | $46M | $1M | $151.0K |
| Betriebsgewinnmarge % | -148.6% | -7518.4% | — |
| Nettoergebnis | $-49M | $-72M | $4M |
| Verwässerte EPS | $-1.10 | $-7.26 | $0.29 |
Bilanz
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Liquiditätsgrad | 4.7 | 27.8 | — |
| Quick Ratio | 4.6 | 27.3 | — |
Cashflow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Freier Cashflow | $110M | $-70M | — |
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Institutionelle Eigentümer (13F) 170 Einreicher · $1.5B gesamt · Stand 30. Juni 2026
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
Institutionelle Aktivität — Q2 2026 vs. Vorquartal
| Neue Positionen | Geschlossene Positionen | Erhöht | Abgenommen | Nettoveränderung der Aktien |
|---|---|---|---|---|
| 62 (+38 vs. Vorquartal) | 15 (-7 vs. Vorquartal) | 43 (+3 vs. Vorquartal) | 33 (+4 vs. Vorquartal) | +2.8M |
Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $234.291.284 | 6.995.858 | 15,96% | Aktien |
| TRV GP V, LLC | $208.160.143 | 6.215.591 | 14,18% | Aktien |
| Driehaus Capital Management LLC | $148.463.112 | 4.433.058 | 10,11% | Aktien |
| TRV GP VI, LLC | $141.048.460 | 4.211.659 | 9,61% | Aktien |
| SAMSARA BIOCAPITAL, LLC | $105.464.297 | 3.149.128 | 7,18% | Aktien |
| Siren, L.L.C. | $63.631.000 | 1.900.000 | 4,33% | Aktien |
| GOLDMAN SACHS GROUP INC | $57.564.688 | 1.718.862 | 3,92% | Aktien |
| Avoro Capital Advisors LLC | $44.792.875 | 1.337.500 | 3,05% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $40.913.829 | 1.221.673 | 2,79% | Aktien |
| PRIMECAP MANAGEMENT CO/CA/ | $39.095.624 | 1.167.382 | 2,66% | Aktien |
| First Light Asset Management, LLC | $32.259.577 | 963.260 | 2,20% | Aktien |
| ADAR1 Capital Management, LLC | $31.505.617 | 940.747 | 2,15% | Aktien |
| STATE STREET CORP | $21.856.579 | 652.630 | 1,49% | Aktien |
| JANUS HENDERSON GROUP PLC | $21.333.558 | 890.754 | 1,45% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $19.943.040 | 595.346 | 1,36% | Aktien |
| Casdin Capital, LLC | $18.528.945 | 553.268 | 1,26% | Aktien |
| Catalio Capital Management, LP | $17.955.730 | 536.152 | 1,22% | Aktien |
| LOOMIS SAYLES & CO L P | $17.416.173 | 520.041 | 1,19% | Aktien |
| Caption Management, LLC | $14.735.600 | 440.000 | 1,00% | Kaufoption |
| ALGERT GLOBAL LLC | $13.311.840 | 397.487 | 0,91% | Aktien |
| Balyasny Asset Management L.P. | $11.736.303 | 350.442 | 0,80% | Aktien |
| Longaeva Partners L.P. | $9.985.747 | 298.171 | 0,68% | Aktien |
| Soleus Capital Management, L.P. | $9.209.750 | 275.000 | 0,63% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $8.774.380 | 262.000 | 0,60% | Kaufoption |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $7.708.862 | 230.184 | 0,52% | Aktien |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $7.458.290 | 222.702 | 0,51% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $7.397.439 | 220.885 | 0,50% | Aktien |
| TUDOR INVESTMENT CORP ET AL | $6.698.000 | 200.000 | 0,46% | Kaufoption |
| Caption Management, LLC | $6.698.000 | 200.000 | 0,46% | Verkaufsoption |
| Kalehua Capital Management LLC | $6.515.279 | 194.544 | 0,44% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $6.264.003 | 187.041 | 0,43% | Aktien |
| Woodline Partners LP | $6.213.567 | 185.535 | 0,42% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $5.547.819 | 165.656 | 0,38% | Aktien |
| VANGUARD GROUP INC | $4.171.991 | 149.641 | 0,28% | Aktien |
| TUDOR INVESTMENT CORP ET AL | $3.349.000 | 100.000 | 0,23% | Verkaufsoption |
| CITADEL ADVISORS LLC | $2.739.482 | 81.800 | 0,19% | Kaufoption |
| UBS Group AG | $2.551.067 | 76.174 | 0,17% | Aktien |
| LAZARD ASSET MANAGEMENT LLC | $2.525.983 | 75.425 | 0,17% | Aktien |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $2.499.995 | 74.649 | 0,17% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $2.284.319 | 68.209 | 0,16% | Aktien |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2.283.348 | 68.180 | 0,16% | Aktien |
| HUSSMAN STRATEGIC ADVISORS, INC. | $2.109.870 | 63.000 | 0,14% | Aktien |
| AMERICAN CENTURY COMPANIES INC | $2.041.986 | 60.973 | 0,14% | Aktien |
| DIADEMA PARTNERS LP | $1.999.353 | 59.700 | 0,14% | Verkaufsoption |
| JANE STREET GROUP, LLC | $1.915.628 | 57.200 | 0,13% | Kaufoption |
| XTX Topco Ltd | $1.824.837 | 54.489 | 0,12% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $1.693.321 | 50.562 | 0,12% | Aktien |
| Elmind Capital, LP | $1.655.880 | 49.444 | 0,11% | Aktien |
| BARCLAYS PLC | $1.647.541 | 49.195 | 0,11% | Aktien |
| Sofinnova Investments, Inc. | $1.590.976 | 47.506 | 0,11% | Aktien |
| D. E. Shaw & Co., Inc. | $1.556.716 | 46.483 | 0,11% | Aktien |
| Voleon Capital Management LP | $1.488.128 | 44.435 | 0,10% | Aktien |
| RENAISSANCE TECHNOLOGIES LLC | $1.387.122 | 41.419 | 0,09% | Aktien |
| Caption Management, LLC | $1.272.821 | 38.006 | 0,09% | Aktien |
| BANK OF AMERICA CORP /DE/ | $1.201.453 | 35.875 | 0,08% | Aktien |
| Alyeska Investment Group, L.P. | $1.172.150 | 35.000 | 0,08% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.135.311 | 33.900 | 0,08% | Verkaufsoption |
| Brevan Howard Capital Management LP | $986.347 | 29.452 | 0,07% | Aktien |
| HighVista Strategies LLC | $982.496 | 29.337 | 0,07% | Aktien |
| TUDOR INVESTMENT CORP ET AL | $970.071 | 28.966 | 0,07% | Aktien |
| RHUMBLINE ADVISERS | $925.521 | 27.636 | 0,06% | Aktien |
| JANE STREET GROUP, LLC | $871.946 | 26.036 | 0,06% | Aktien |
| Trexquant Investment LP | $858.851 | 25.645 | 0,06% | Aktien |
| Logos Global Management LP | $788.623 | 23.548 | 0,05% | Aktien |
| FMR LLC | $778.308 | 23.240 | 0,05% | Aktien |
| FOX RUN MANAGEMENT, L.L.C. | $738.053 | 22.038 | 0,05% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $718.497 | 29.900 | 0,05% | Aktien |
| TWO SIGMA ADVISERS, LP | $716.516 | 25.700 | 0,05% | Aktien |
| Squarepoint Ops LLC | $710.624 | 21.219 | 0,05% | Aktien |
| STRS OHIO | $703.290 | 21.000 | 0,05% | Aktien |
| FRED ALGER MANAGEMENT, LLC | $701.883 | 20.958 | 0,05% | Aktien |
| Jump Financial, LLC | $676.498 | 20.200 | 0,05% | Aktien |
| Swiss National Bank | $663.102 | 19.800 | 0,05% | Aktien |
| WELLS FARGO & COMPANY/MN | $657.677 | 19.638 | 0,04% | Aktien |
| Aquatic Capital Management LLC | $583.630 | 17.427 | 0,04% | Aktien |
| BlackRock, Inc. | $582.626 | 17.397 | 0,04% | Aktien |
| Engineers Gate Manager LP | $581.052 | 17.350 | 0,04% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $567.522 | 16.946 | 0,04% | Aktien |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $555.833 | 16.597 | 0,04% | Aktien |
| CITIGROUP INC | $553.623 | 16.531 | 0,04% | Aktien |
| Nuveen Asset Management, LLC | $548.707 | 23.961 | 0,04% | Aktien |
| State of Wyoming | $548.533 | 16.379 | 0,04% | Aktien |
| Vanguard Global Advisers, LLC | $544.112 | 16.247 | 0,04% | Aktien |
| Bank of New York Mellon Corp | $516.650 | 15.427 | 0,04% | Aktien |
| AQR CAPITAL MANAGEMENT LLC | $510.421 | 15.241 | 0,03% | Aktien |
| Verdad Advisers, LP | $434.365 | 12.970 | 0,03% | Aktien |
| MetLife Investment Management, LLC | $431.351 | 12.880 | 0,03% | Aktien |
| Man Group plc | $384.097 | 11.469 | 0,03% | Aktien |
| FEDERATED HERMES, INC. | $368.055 | 10.990 | 0,03% | Aktien |
| China Universal Asset Management Co., Ltd. | $360.821 | 10.774 | 0,02% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $341.364 | 10.193 | 0,02% | Aktien |
| Gotham Asset Management, LLC | $312.194 | 9.322 | 0,02% | Aktien |
| Virtus Investment Advisers, LLC | $304.826 | 9.102 | 0,02% | Aktien |
| CANADA PENSION PLAN INVESTMENT BOARD | $298.061 | 8.900 | 0,02% | Aktien |
| Invesco Ltd. | $285.737 | 8.532 | 0,02% | Aktien |
| NEW YORK STATE COMMON RETIREMENT FUND | $284.665 | 8.500 | 0,02% | Aktien |
| FIRST TRUST ADVISORS LP | $259.179 | 7.739 | 0,02% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $248.496 | 7.420 | 0,02% | Aktien |
| Quantinno Capital Management LP | $245.482 | 7.330 | 0,02% | Aktien |
| Rangeley Capital, LLC | $241.128 | 7.200 | 0,02% | Aktien |
Unternehmensinsider 15 Insider · 6 Führungskräfte · 8 Direktoren
| Insider | Rolle | Letzte Aktivität | Gehaltene Aktien | Käufe 12m | Verkäufe 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Jeffrey Finer | Chief Executive Officer | 6. Februar 2026 A | 826.907 | 0 | 0 | $0 |
| Gil M Labrucherie | Chief Financial Officer | 6. Februar 2026 A | 40.000 | 0 | 0 | $0 |
| Samira Shaikhly | Chief People Officer | 29. Juni 2026 M | 793 | 0 | 8 | $-2.802.156 |
| Uwe Klein | SVP, Biological Sciences | 6. Februar 2026 A | 23.008 | 0 | 0 | $0 |
| Jae B. Kim | Chief Medical Officer | 6. Februar 2026 A | — | 0 | 0 | $0 |
| Mark Andrew Wilson | Chief Legal Officer | 6. Februar 2026 A | — | 0 | 0 | $0 |
| Abraham Bassan | Direktor | 26. Juni 2026 A | — | 0 | 0 | $0 |
| Jake Simson | Direktor | 26. Juni 2026 A | — | 0 | 0 | $0 |
| Bernard Coulie | Direktor | 26. Juni 2026 A | — | 0 | 0 | $0 |
| Alan Ezekowitz | Direktor | 26. Juni 2026 A | 117.420 | 0 | 0 | $0 |
| Keith Michael Gottesdiener | Direktor | 26. Juni 2026 A | — | 0 | 0 | $0 |
| Jeffrey K Tong | Direktor | 26. Juni 2026 A | — | 0 | 0 | $0 |
| Shalini Sharp | Direktor | 26. Juni 2026 A | — | 0 | 0 | $0 |
| Elizabeth Bhatt | — | 11. August 2026 M | 174.209 | 0 | 7 | $-1.449.169 |
| Daniel D. Long | — | 3. August 2026 M | 96.412 | 0 | 7 | $-825.272 |
Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten
Aktivisten & 5%+-Eigentümer 1 Beteiligung
Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.
| Anmelder | Eingereicht | Beteiligung | Status | Zweck | Einreichung |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×2 Einreichungen | 14. August 2026 | 11,80% | Änderung | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF-Besitz Gehalten von 40 ETFs
Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.
| Fonds | Gewicht | Anteile | Stand | Quelle |
|---|---|---|---|---|
| PILL · Direxion Shares ETF Trust | 0,69% | 3.760 NS | 30. April 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,69% | 10.849 NS | 30. April 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,44% | 7.698 NS | 31. Mai 2026 | N-PORT |
| IHE · iShares Trust | 0,20% | 81.879 SH | 8. August 2026 | Täglich |
| FSCC · Federated Hermes ETF Trust | 0,14% | 12.566 NS | 31. Mai 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,12% | 2.451 SH | 8. August 2026 | Täglich |
| IBB · iShares Trust | 0,08% | 202.051 SH | 8. August 2026 | Täglich |
| VFMO · VANGUARD WELLINGTON FUND | 0,08% | 48.858 SH | 8. August 2026 | Täglich |
| BIB · ProShares Trust | 0,07% | 1.657 NS | 31. Mai 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,06% | 51.545 NS | 31. Mai 2026 | N-PORT |
| JPSE · J.P. Morgan Exchange-Traded Fund Tr… | 0,04% | 10.731 NS | 30. April 2026 | N-PORT |
| IWO · iShares Trust | 0,04% | 135.471 SH | 8. August 2026 | Täglich |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,03% | 15.806 SH | 8. August 2026 | Täglich |
| IWM · iShares Trust | 0,03% | 566.763 SH | 8. August 2026 | Täglich |
| ISCG · iShares Trust | 0,02% | 6.294 SH | 8. August 2026 | Täglich |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 127.487 SH | 8. August 2026 | Täglich |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,02% | 6.423 SH | 8. August 2026 | Täglich |
| IWN · iShares Trust | 0,02% | 68.929 SH | 8. August 2026 | Täglich |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,02% | 1.228 SH | 8. August 2026 | Täglich |
| ITWO · ProShares Trust | 0,02% | 1.006 NS | 31. Mai 2026 | N-PORT |
| RSSL · Global X Funds | 0,02% | 9.265 NS | 30. April 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 108.128 NS | 31. Mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 906 SH | 8. August 2026 | Täglich |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,01% | 8.859 SH | 8. August 2026 | Täglich |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 263.629 SH | 8. August 2026 | Täglich |
| UWM · ProShares Trust | 0,01% | 787 NS | 31. Mai 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 797 NS | 31. Mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 17.360 NS | 31. Mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,00% | 5.127 NS | 30. April 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 20 NS | 31. Mai 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 16.325 NS | 30. April 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 675 NS | 31. Mai 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 6.883 SH | 8. August 2026 | Täglich |
| ITOT · iShares Trust | 0,00% | 29.774 SH | 8. August 2026 | Täglich |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 11.580 NS | 31. Mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 418 NS | 30. April 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 672 NS | 31. Mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 927.665 SH | 8. August 2026 | Täglich |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 1.866 SH | 8. August 2026 | Täglich |
| VHT · VANGUARD WORLD FUND | 0,00% | 29.744 SH | 8. August 2026 | Täglich |