Earnings History
EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.04%
Period
EPS Actual
EPS Est
Surprise
March 31, 2026
$-0.63
$-0.40
-0.23%
Dec. 31, 2025
$-0.39
$-0.35
-0.04%
Sept. 30, 2025
$-0.37
$-0.31
-0.06%
June 30, 2025
$-0.32
$-0.41
0.09%
March 31, 2025
$-0.32
$-0.36
0.04%
Peer comparison (GICS sub-industry)
Key metrics vs sector peers
Ticker
Market Cap
P/E
Rev YoY
Net Margin
ROE
Gross Margin
ANVS
$94M
-2.5
—
—
-164.0%
—
DWTX
$124M
-0.6
123.6%
—
-83.8%
—
ELTX
—
-3.1
—
—
—
—
GOSS
$724M
-4.1
-57.7%
-351.5%
201.8%
—
FRMM
—
—
—
-6881.3%
-368.1%
—
SPRO
$131M
15.5
39.2%
12.8%
18.7%
—
IBIO
$15M
-0.4
77.8%
-4594.2%
-101.5%
—
CRDF
$192M
-4.1
-13.2%
-7732.0%
-88.2%
—
RNTX
—
-0.6
—
—
—
—
NMAD
—
—
—
—
—
—
Full Fundamentals
All metrics by year — income statement, balance sheet, cash flow
Income Statement15
Annual Income Statement data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Revenue
$0
$0
$0
$0
$0
$0
$0
R&D Expense
$25M
$20M
$39M
$17M
$8M
$3M
$776.3K
SG&A Expense
$4M
$7M
$6M
$9M
$6M
$4M
$829.4K
Operating Expenses
$30M
$27M
$45M
$26M
$15M
$7M
$2M
Operating Income
$-30M
$-27M
$-45M
$-26M
$-15M
$-7M
$-2M
Interest Income
$699.1K
$331.8K
$667.9K
·
·
·
·
Other Non-op
$841.1K
$2M
$-11M
$182.7K
$50.1K
$1M
$614.6K
Pretax Income
·
·
$-56M
$-25M
$-14M
$-5M
$-991.0K
Income Tax
$0
·
·
·
·
·
$0
Net Income
$-29M
$-25M
$-56M
$-25M
$-14M
$-5M
$-991.0K
EPS (Basic)
$-1.40
$-2.02
$-6.23
$-3.10
$-1.90
$-0.87
·
EPS (Diluted)
$-1.40
$-2.31
$-6.23
$-3.10
$-1.90
$-0.87
·
Shares (Basic)
20,551,997
12,182,475
9,023,138
8,162,326
7,626,278
6,308,961
·
Shares (Diluted)
20,551,997
12,235,444
9,023,138
8,162,326
7,626,278
6,308,961
·
EBITDA
$-30M
$-27M
$-45M
$-26M
$-15M
$-7M
·
Balance Sheet12
Annual Balance Sheet data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Cash & Equivalents
$20M
$11M
$6M
$28M
$46M
$8M
$1.9K
Current Assets
·
·
$10M
$36M
$46M
$8M
$747.5K
Total Assets
$21M
$14M
$10M
$36M
$46M
$8M
$1M
Accounts Payable
$3M
$2M
$1M
$4M
$688.1K
$341.9K
$1M
Current Liabilities
$4M
$4M
$4M
$8M
$2M
$578.4K
$2M
Total Liabilities
$4M
$5M
$18M
$8M
$2M
$578.4K
$3M
Common Stock
$2.7K
$1.4K
$1.1K
$816
$810
$689
$28
Paid-in Capital
$181M
$144M
$103M
$82M
$73M
$22M
$200.6K
Retained Earnings
$-164M
$-135M
$-110M
$-54M
$-29M
$-14M
$-9M
Stockholders' Equity
$17M
$9M
$-8M
$28M
$44M
$8M
$-9M
Liabilities + Equity
$21M
$14M
$10M
$36M
$46M
$8M
$1M
Shares Outstanding
27,199,139
14,141,521
10,519,933
8,163,923
8,100,570
6,891,608
282,614
Cash Flow6
Annual Cash Flow data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Stock-based Comp
$2M
$4M
$5M
$9M
$5M
$2M
$8.5K
Operating Cash Flow
$-26M
$-22M
$-40M
$-17M
$-9M
$-4M
$-476.5K
Stock Issued
·
$19M
$17M
·
$47M
$12M
·
Net Stock Activity
·
$19M
$17M
·
$47M
$12M
·
Financing Cash Flow
$35M
$27M
$17M
$4.6K
$47M
$12M
$443.1K
Net Change in Cash
$9M
$5M
$-23M
$-17M
$38M
$8M
$-33.5K
Profitability2
Annual Profitability data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
ROA
-164.8%
-203.8%
-243.2%
-69.3%
-53.5%
-118.3%
·
ROE
-164.0%
-300.4%
10287.8%
-80.5%
-31.8%
-65.6%
·
Liquidity & Solvency2
Annual Liquidity & Solvency data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Current Ratio
·
·
2.4
4.7
30.5
14.0
·
Quick Ratio
5.4
2.7
1.3
3.7
30.3
14.0
·
Efficiency1
Annual Efficiency data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Asset Turnover
0.0
0.0
0.0
0.0
0.0
0.0
·
Per Share5
Annual Per Share data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Book Value / Share
$0.62
$0.66
$-0.74
$3.47
$5.49
$1.09
·
Revenue / Share
$0.00
$0.00
$0.00
$0.00
$0.00
·
·
Cash Flow / Share
$-1.25
$-1.79
$-4.43
$-2.12
$-1.20
·
·
Cash / Share
$0.72
$0.75
$0.55
$3.48
$5.64
$1.17
·
EPS (TTM)
$-1.40
$-2.31
$-6.23
$-3.10
$-1.90
$-0.87
·
Valuation (TTM)8
Annual Valuation (TTM) data for ANVS
Metric
Trend
2025
2024
2023
2022
2021
2020
2019
Revenue TTM
$0
$0
$0
$0
$0
$0
$0
Net Income TTM
$-29M
$-25M
$-56M
$-25M
$-14M
$-5M
$-991.0K
Market Cap
$94M
$71M
$197M
$110M
$142M
$52M
·
P/E
-2.5
-2.2
-3.0
-4.3
-9.3
-8.7
·
P/B
5.6
7.6
-25.4
3.9
3.2
6.9
·
P / Tangible Book
5.6
7.6
·
3.9
3.2
6.9
·
P / Cash Flow
-3.7
-3.2
-4.9
-6.3
-15.6
-13.1
·
Earnings Yield
-40.5%
-45.9%
-33.3%
-23.1%
-10.8%
-11.5%
·
Income Statement15
Quarterly Income Statement data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Revenue
$0
$0
$0
$0
$0
$0
·
$0
$0
$0
·
$0
$0
$0
·
$0
R&D Expense
$12M
$17M
$9M
$6M
$5M
$5M
$5M
$3M
$6M
$7M
$9M
$14M
$8M
$8M
$6M
$4M
SG&A Expense
$2M
$1M
$955.2K
$1M
$1M
$1M
$2M
$2M
$2M
$1M
$2M
$1M
$1M
$2M
$2M
$2M
Operating Expenses
$14M
$18M
$10M
$7M
$6M
$6M
$7M
$4M
$8M
$8M
$10M
$15M
$10M
$10M
$8M
$6M
Operating Income
$-14M
$-18M
$-10M
$-7M
$-6M
$-6M
$-7M
$-4M
$-8M
$-8M
$-10M
$-15M
$-10M
$-10M
$-8M
$-6M
Interest Income
$160.2K
$137.8K
$167.7K
$152.3K
$191.4K
$187.6K
$126.3K
$135.4K
$26.0K
$44.2K
$66.1K
$146.7K
·
·
·
·
Other Non-op
$-443.1K
$405.8K
$-128.3K
$172.3K
$51.4K
$745.6K
$870.2K
$-8M
$3M
$7M
$-12M
$146.7K
$222.6K
$232.5K
$74.2K
$52.9K
Pretax Income
·
·
·
·
·
·
·
$-13M
$-5M
$-1M
·
$-15M
$-10M
$-10M
$-8M
$-6M
Income Tax
$0
$0
$0
$0
$0
$0
·
$0
$0
$0
·
$0
$0
$0
·
$0
Net Income
$-15M
$-18M
$-10M
$-7M
$-6M
$-6M
$-6M
$-13M
$-5M
$-1M
$-22M
$-15M
$-10M
$-10M
$-8M
$-6M
EPS (Basic)
$-0.40
$-0.63
$-0.39
$-0.37
$-0.32
$-0.32
$-0.51
$-0.97
$-0.44
$-0.10
$-2.34
$-1.63
$-1.07
$-1.19
$-0.94
$-0.79
EPS (Diluted)
$-0.40
$-0.63
$-0.39
$-0.37
$-0.32
$-0.32
$-0.18
$-0.97
$-0.44
$-0.72
$-2.46
$-1.63
$-1.07
$-1.07
$-0.94
$-0.79
Shares (Basic)
37,518,778
27,847,884
-36,050,539
19,685,071
19,486,231
17,431,234
-22,726,157
12,975,808
11,307,759
10,625,065
-17,135,434
9,012,273
8,951,309
8,194,990
-16,322,965
8,163,923
Shares (Diluted)
37,518,778
27,847,884
-36,050,539
19,685,071
19,486,231
17,431,234
-22,872,894
12,975,808
11,307,759
10,824,771
-17,891,753
9,012,273
8,951,309
8,951,309
-16,322,965
8,163,923
EBITDA
$-14M
$-18M
·
$-7M
·
$-6M
·
$-4M
$-8M
$-8M
·
$-15M
$-10M
$-10M
·
$-8M
Balance Sheet12
Quarterly Balance Sheet data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Cash & Equivalents
$19M
$14M
$20M
$15M
$17M
$22M
$11M
$13M
$4M
$3M
$6M
$6M
$16M
$17M
$28M
$32M
Current Assets
·
·
·
·
·
·
·
·
·
$8M
·
$10M
$23M
$26M
$36M
$32M
Total Assets
$22M
$16M
$21M
$17M
$21M
$27M
$14M
$14M
$5M
$8M
$10M
$10M
$23M
$26M
$36M
$32M
Accounts Payable
$3M
$5M
$3M
$2M
$974.3K
$1M
$2M
$4M
$3M
$4M
$1M
$2M
$1M
$4M
$4M
$2M
Current Liabilities
$6M
$13M
$4M
$4M
$3M
$3M
$4M
$5M
$4M
$5M
$4M
$4M
$2M
$5M
$8M
$3M
Total Liabilities
$26M
$13M
$4M
$4M
$3M
$3M
$5M
$7M
$7M
$11M
$18M
$4M
$2M
$5M
$8M
$3M
Common Stock
$4.3K
$2.9K
$2.7K
$2.0K
$1.9K
$1.9K
$1.4K
$1.3K
$1.2K
$1.1K
$1.1K
$902
$902
$822
$816
$816
Paid-in Capital
$192M
$184M
$181M
$167M
$165M
$164M
$144M
$136M
$115M
$108M
$103M
$95M
$94M
$84M
$82M
$81M
Retained Earnings
$-196M
$-181M
$-164M
$-154M
$-147M
$-140M
$-135M
$-129M
$-116M
$-111M
$-110M
$-88M
$-73M
$-64M
$-54M
$-51M
Stockholders' Equity
$-4M
$3M
$17M
$13M
$18M
$24M
$9M
$7M
$-2M
$-3M
$-8M
$7M
$21M
$20M
$28M
$30M
Liabilities + Equity
$22M
$16M
$21M
$17M
$21M
$27M
$14M
$14M
$5M
$8M
$10M
$10M
$23M
$26M
$36M
$32M
Shares Outstanding
42,606,152
28,537,302
27,199,139
20,187,904
19,486,231
19,486,231
14,141,521
13,283,667
11,721,480
11,011,299
10,519,933
9,012,273
9,012,273
8,216,678
8,163,923
8,163,923
Cash Flow6
Quarterly Cash Flow data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Stock-based Comp
$2M
$182.8K
$356.5K
$444.6K
$496.6K
$499.9K
$1M
$393.1K
$2M
$364.8K
$882.4K
$632.2K
$2M
$2M
$1M
$2M
Operating Cash Flow
$-22M
$-9M
$-9M
$-3M
$-5M
$-8M
$-8M
$-3M
$-3M
$-7M
$-9M
$-9M
$-10M
$-12M
$-4M
$-4M
Stock Issued
·
·
·
·
·
·
·
$4M
$4M
$4M
$8M
$0
·
·
·
·
Net Stock Activity
·
·
·
·
·
·
·
·
·
$4M
·
·
·
·
·
·
Financing Cash Flow
$26M
$4M
$13M
$2M
$0
$20M
$6M
$12M
$4M
$4M
$9M
$0
$9M
$7.4K
$0
$0
Net Change in Cash
$5M
$-5M
$4M
$-2M
$-5M
$12M
$-2M
$9M
$860.8K
$-3M
$-600.2K
$-9M
$-1M
$-12M
$-4M
$-4M
Profitability3
Quarterly Profitability data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
ROA
-68.2%
-81.9%
·
-46.0%
·
-32.0%
·
-102.8%
-36.0%
-6.4%
·
-68.9%
-32.1%
-28.3%
·
-19.0%
ROE
-210.6%
-129.6%
·
-71.8%
·
-53.5%
·
-184.2%
-52.9%
-12.7%
·
-80.4%
-34.1%
-31.3%
·
-19.9%
ROIC
·
·
·
·
·
·
·
-62.1%
443.4%
232.8%
·
-223.2%
-47.0%
-49.5%
·
·
Liquidity & Solvency2
Quarterly Liquidity & Solvency data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Current Ratio
·
·
·
·
·
·
·
·
·
1.6
·
2.9
11.0
4.7
·
12.9
Quick Ratio
2.9
1.1
·
4.1
·
8.9
·
2.3
1.0
0.6
·
1.8
7.6
3.1
·
12.7
Efficiency1
Quarterly Efficiency data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Asset Turnover
·
0.0
·
·
·
0.0
·
·
·
0.0
·
·
·
0.0
·
·
Per Share5
Quarterly Per Share data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Book Value / Share
$-0.10
$0.11
·
$0.65
·
$1.23
·
$0.53
$-0.15
$-0.30
·
$0.74
$2.30
$2.45
·
$3.67
Revenue / Share
·
$0.00
·
·
·
$0.00
·
·
·
$0.00
·
·
·
$0.00
·
·
Cash Flow / Share
·
$-0.32
·
·
·
$-0.46
·
·
·
$-0.65
·
·
·
$-1.42
·
·
Cash / Share
$0.44
$0.50
·
$0.76
·
$1.14
·
$0.95
$0.34
$0.28
·
$0.71
$1.74
$2.04
·
$3.92
EPS (TTM)
$-1.72
$-1.64
·
$-1.98
$-2.05
$-2.45
·
$-3.76
$-3.86
$-4.49
·
$-4.56
$-3.66
$-3.23
·
$-2.51
Valuation (TTM)7
Quarterly Valuation (TTM) data for ANVS
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Q4 2023
Q3 2023
Q2 2023
Q1 2023
Q4 2022
Q3 2022
Net Income TTM
$-46M
$-37M
·
$-32M
$-29M
$-24M
·
$-33M
$-30M
$-35M
·
$-40M
$-32M
$-27M
·
$-20M
Market Cap
$79M
$64M
·
$42M
·
$29M
·
$107M
$68M
$131M
·
$86M
$129M
$127M
·
$112M
P/E
-1.1
-1.4
·
-1.0
-1.1
-0.6
·
-2.1
-1.5
-2.7
·
-2.1
-3.9
-4.8
·
-5.5
P/B
-18.6
20.4
·
3.2
·
1.2
·
15.2
-38.6
-39.1
·
12.8
6.2
6.3
·
3.7
P / Tangible Book
·
20.4
·
3.2
2.3
1.2
·
15.2
·
·
·
12.8
6.2
6.3
·
3.7
P / Cash Flow
·
-7.1
·
·
·
-3.6
·
·
·
-18.6
·
·
·
-10.9
·
·
Earnings Yield
-92.5%
-73.5%
·
-95.7%
-94.5%
-163.3%
·
-46.7%
-67.0%
-37.7%
·
-48.0%
-25.6%
-21.0%
·
-18.3%
Financial Statements
Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
2025-12-31
2024-12-31
2023-12-31
2022-12-31
2022-09-30
Revenue
$0
$0
$0
$0
—
Net Income
$-29M
$-25M
$-56M
$-25M
—
Diluted EPS
$-1.40
$-2.31
$-6.23
$-3.10
—
Balance Sheet
2025-12-31
2024-12-31
2023-12-31
2022-12-31
2022-09-30
Current Ratio
—
—
2.4
4.7
—
Quick Ratio
5.4
2.7
1.3
3.7
—
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Institutional owners (13F)
73 filers · $18.8M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
New positions
Exited positions
Increased
Decreased
Net shares change
16
(+2 vs prior Q)
11
(+4 vs prior Q)
21
(+6 vs prior Q)
7
(-3 vs prior Q)
+5.8M
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners
1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership
Held by 4 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.