ANVS Annovis Bio, Inc. Common Stock
$2.26
Price · May 22, 2026
Fundamentals as of May 15, 2026
52W Range
$2–$6
18% of range
Analyst Rating
BUY
10 analysts
Price Target
$12
+453% upside
P/E (TTM)
-2.5
ROE
-164.0%
Net Profit Margin
—
ANVS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$2.26
Market Cap
$94M
P/E (TTM)
-2.5
EPS (TTM)
$-1.40
Revenue (TTM)
$0
Div Yield
—
ROE
-164.0%
Debt/Equity
—
52W Range
$2 – $6
ANVS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$0
2019-12-31
→
2025-12-31
EPS
$-1.40
2020-12-31
→
2025-12-31
Free Cash Flow
—
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
ANVS
Peer Median
P/E (TTM)
-2.5
25.0
P/B
5.6
1.5
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
ANVS
Peer Median
ROA
-164.8%
-33.6%
ROE
-164.0%
-49.1%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
ANVS
Peer Median
Quick Ratio
5.4
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
ANVS
Peer Median
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
ANVS
Peer Median
ANVS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
10 analysts
- Strong Buy 2 20.0%
- Buy 7 70.0%
- Hold 1 10.0%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
2 analysts · 2026-05-18
Median
$12.50
← Below all targets
$2.26
Low
$8.00
High
$17.00
Median target
$12.50
+453.1%
Mean target
$12.50
+453.1%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.04%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.63 | $-0.40 | -0.23% |
| Dec. 31, 2025 | $-0.39 | $-0.35 | -0.04% |
| Sept. 30, 2025 | $-0.37 | $-0.31 | -0.06% |
| June 30, 2025 | $-0.32 | $-0.41 | 0.09% |
| March 31, 2025 | $-0.32 | $-0.36 | 0.04% |
Peer Comparison Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| ANVS | $94M | -2.5 | — | — | -164.0% | — |
| ATRA | $132M | 7.0 | -6.3% | 27.1% | -88.9% | — |
| CLNN | $64M | — | -41.5% | -13086.5% | 200.2% | — |
| LNAI | $513M | -2.7 | — | — | -586.4% | — |
| EXOZ | $92M | -10.0 | — | — | -172.3% | — |
| RLYB | $4M | -0.4 | 34.9% | -1046.4% | -17.3% | — |
| SERA | — | -4.4 | 5.2% | -39417.3% | -39.0% | — |
| CTOR | $170M | -6.0 | — | — | -61.5% | — |
| ACET | $81M | -0.5 | — | — | -79.8% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 15
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| R&D Expense | $25M | $20M | $39M | $17M | $8M | $3M | $776.3K | |
| SG&A Expense | $4M | $7M | $6M | $9M | $6M | $4M | $829.4K | |
| Operating Expenses | $30M | $27M | $45M | $26M | $15M | $7M | $2M | |
| Operating Income | $-30M | $-27M | $-45M | $-26M | $-15M | $-7M | $-2M | |
| Interest Income | $699.1K | $331.8K | $667.9K | · | · | · | · | |
| Other Non-op | $841.1K | $2M | $-11M | $182.7K | $50.1K | $1M | $614.6K | |
| Pretax Income | · | · | $-56M | $-25M | $-14M | $-5M | $-991.0K | |
| Income Tax | $0 | · | · | · | · | · | $0 | |
| Net Income | $-29M | $-25M | $-56M | $-25M | $-14M | $-5M | $-991.0K | |
| EPS (Basic) | $-1.40 | $-2.02 | $-6.23 | $-3.10 | $-1.90 | $-0.87 | · | |
| EPS (Diluted) | $-1.40 | $-2.31 | $-6.23 | $-3.10 | $-1.90 | $-0.87 | · | |
| Shares (Basic) | 20,551,997 | 12,182,475 | 9,023,138 | 8,162,326 | 7,626,278 | 6,308,961 | · | |
| Shares (Diluted) | 20,551,997 | 12,235,444 | 9,023,138 | 8,162,326 | 7,626,278 | 6,308,961 | · | |
| EBITDA | $-30M | $-27M | $-45M | $-26M | $-15M | $-7M | · |
Balance Sheet 12
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $20M | $11M | $6M | $28M | $46M | $8M | $1.9K | |
| Current Assets | · | · | $10M | $36M | $46M | $8M | $747.5K | |
| Total Assets | $21M | $14M | $10M | $36M | $46M | $8M | $1M | |
| Accounts Payable | $3M | $2M | $1M | $4M | $688.1K | $341.9K | $1M | |
| Current Liabilities | $4M | $4M | $4M | $8M | $2M | $578.4K | $2M | |
| Total Liabilities | $4M | $5M | $18M | $8M | $2M | $578.4K | $3M | |
| Common Stock | $2.7K | $1.4K | $1.1K | $816 | $810 | $689 | $28 | |
| Paid-in Capital | $181M | $144M | $103M | $82M | $73M | $22M | $200.6K | |
| Retained Earnings | $-164M | $-135M | $-110M | $-54M | $-29M | $-14M | $-9M | |
| Stockholders' Equity | $17M | $9M | $-8M | $28M | $44M | $8M | $-9M | |
| Liabilities + Equity | $21M | $14M | $10M | $36M | $46M | $8M | $1M | |
| Shares Outstanding | 27,199,139 | 14,141,521 | 10,519,933 | 8,163,923 | 8,100,570 | 6,891,608 | 282,614 |
Cash Flow 6
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $2M | $4M | $5M | $9M | $5M | $2M | $8.5K | |
| Operating Cash Flow | $-26M | $-22M | $-40M | $-17M | $-9M | $-4M | $-476.5K | |
| Stock Issued | · | $19M | $17M | · | $47M | $12M | · | |
| Net Stock Activity | · | $19M | $17M | · | $47M | $12M | · | |
| Financing Cash Flow | $35M | $27M | $17M | $4.6K | $47M | $12M | $443.1K | |
| Net Change in Cash | $9M | $5M | $-23M | $-17M | $38M | $8M | $-33.5K |
Profitability 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -164.8% | -203.8% | -243.2% | -69.3% | -53.5% | -118.3% | · | |
| ROE | -164.0% | -300.4% | 10287.8% | -80.5% | -31.8% | -65.6% | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | · | 2.4 | 4.7 | 30.5 | 14.0 | · | |
| Quick Ratio | 5.4 | 2.7 | 1.3 | 3.7 | 30.3 | 14.0 | · |
Efficiency 1
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | · |
Valuation (TTM) 8
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income TTM | $-29M | $-25M | $-56M | $-25M | $-14M | $-5M | $-991.0K | |
| Market Cap | $94M | $71M | $197M | $110M | $142M | $52M | · | |
| P/E | -2.5 | -2.2 | -3.0 | -4.3 | -9.3 | -8.7 | · | |
| P/B | 5.6 | 7.6 | -25.4 | 3.9 | 3.2 | 6.9 | · | |
| P / Tangible Book | 5.6 | 7.6 | · | 3.9 | 3.2 | 6.9 | · | |
| P / Cash Flow | -3.7 | -3.2 | -4.9 | -6.3 | -15.6 | -13.1 | · | |
| Earnings Yield | -40.5% | -45.9% | -33.3% | -23.1% | -10.8% | -11.5% | · |
Income Statement 15
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $0 | |
| R&D Expense | $17M | $9M | $6M | $5M | $5M | $5M | $3M | $6M | $7M | $9M | $14M | $8M | $8M | $6M | $4M | $4M | |
| SG&A Expense | $1M | $955.2K | $1M | $1M | $1M | $2M | $2M | $2M | $1M | $2M | $1M | $1M | $2M | $2M | $2M | $2M | |
| Operating Expenses | $18M | $10M | $7M | $6M | $6M | $7M | $4M | $8M | $8M | $10M | $15M | $10M | $10M | $8M | $6M | $6M | |
| Operating Income | $-18M | $-10M | $-7M | $-6M | $-6M | $-7M | $-4M | $-8M | $-8M | $-10M | $-15M | $-10M | $-10M | $-8M | $-6M | $-6M | |
| Interest Income | $137.8K | $167.7K | $152.3K | $191.4K | $187.6K | $126.3K | $135.4K | $26.0K | $44.2K | $66.1K | $146.7K | · | · | · | · | · | |
| Other Non-op | $405.8K | $-128.3K | $172.3K | $51.4K | $745.6K | $870.2K | $-8M | $3M | $7M | $-12M | $146.7K | $222.6K | $232.5K | $74.2K | $52.9K | $36.0K | |
| Pretax Income | · | · | · | · | · | · | $-13M | $-5M | $-1M | · | $-15M | $-10M | $-10M | $-8M | $-6M | $-6M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $0 | |
| Net Income | $-18M | $-10M | $-7M | $-6M | $-6M | $-6M | $-13M | $-5M | $-1M | $-22M | $-15M | $-10M | $-10M | $-8M | $-6M | $-6M | |
| EPS (Basic) | $-0.63 | $-0.39 | $-0.37 | $-0.32 | $-0.32 | $-0.51 | $-0.97 | $-0.44 | $-0.10 | $-2.34 | $-1.63 | $-1.07 | $-1.19 | $-0.94 | $-0.79 | $-0.73 | |
| EPS (Diluted) | $-0.63 | $-0.39 | $-0.37 | $-0.32 | $-0.32 | $-0.18 | $-0.97 | $-0.44 | $-0.72 | $-2.46 | $-1.63 | $-1.07 | $-1.07 | $-0.94 | $-0.79 | $-0.73 | |
| Shares (Basic) | 27,847,884 | -36,050,539 | 19,685,071 | 19,486,231 | 17,431,234 | -22,726,157 | 12,975,808 | 11,307,759 | 10,625,065 | -17,135,434 | 9,012,273 | 8,951,309 | 8,194,990 | -16,322,965 | 8,163,923 | 8,163,923 | |
| Shares (Diluted) | 27,847,884 | -36,050,539 | 19,685,071 | 19,486,231 | 17,431,234 | -22,872,894 | 12,975,808 | 11,307,759 | 10,824,771 | -17,891,753 | 9,012,273 | 8,951,309 | 8,951,309 | -16,322,965 | 8,163,923 | 8,163,923 | |
| EBITDA | $-18M | · | $-7M | $-6M | $-6M | · | $-4M | $-8M | $-8M | · | $-15M | $-10M | $-10M | · | $-8M | $-9M |
Balance Sheet 12
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $14M | $20M | $15M | $17M | $22M | $11M | $13M | $4M | $3M | $6M | $6M | $16M | $17M | $28M | $32M | $36M | |
| Current Assets | · | · | · | · | · | · | · | · | $8M | · | $10M | $23M | $26M | $36M | $32M | $37M | |
| Total Assets | $16M | $21M | $17M | $21M | $27M | $14M | $14M | $5M | $8M | $10M | $10M | $23M | $26M | $36M | $32M | $37M | |
| Accounts Payable | $5M | $3M | $2M | $974.3K | $1M | $2M | $4M | $3M | $4M | $1M | $2M | $1M | $4M | $4M | $2M | $901.8K | |
| Current Liabilities | $13M | $4M | $4M | $3M | $3M | $4M | $5M | $4M | $5M | $4M | $4M | $2M | $5M | $8M | $3M | $1M | |
| Total Liabilities | $13M | $4M | $4M | $3M | $3M | $5M | $7M | $7M | $11M | $18M | $4M | $2M | $5M | $8M | $3M | $1M | |
| Common Stock | $2.9K | $2.7K | $2.0K | $1.9K | $1.9K | $1.4K | $1.3K | $1.2K | $1.1K | $1.1K | $902 | $902 | $822 | $816 | $816 | $816 | |
| Paid-in Capital | $184M | $181M | $167M | $165M | $164M | $144M | $136M | $115M | $108M | $103M | $95M | $94M | $84M | $82M | $81M | $79M | |
| Retained Earnings | $-181M | $-164M | $-154M | $-147M | $-140M | $-135M | $-129M | $-116M | $-111M | $-110M | $-88M | $-73M | $-64M | $-54M | $-51M | $-43M | |
| Stockholders' Equity | $3M | $17M | $13M | $18M | $24M | $9M | $7M | $-2M | $-3M | $-8M | $7M | $21M | $20M | $28M | $30M | $35M | |
| Liabilities + Equity | $16M | $21M | $17M | $21M | $27M | $14M | $14M | $5M | $8M | $10M | $10M | $23M | $26M | $36M | $32M | $37M | |
| Shares Outstanding | 28,537,302 | 27,199,139 | 20,187,904 | 19,486,231 | 19,486,231 | 14,141,521 | 13,283,667 | 11,721,480 | 11,011,299 | 10,519,933 | 9,012,273 | 9,012,273 | 8,216,678 | 8,163,923 | 8,163,923 | 8,163,923 |
Cash Flow 6
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $182.8K | $356.5K | $444.6K | $496.6K | $499.9K | $1M | $393.1K | $2M | $364.8K | $882.4K | $632.2K | $2M | $2M | $1M | $2M | $2M | |
| Operating Cash Flow | $-9M | $-9M | $-3M | $-5M | $-8M | $-8M | $-3M | $-3M | $-7M | $-9M | $-9M | $-10M | $-12M | $-4M | $-4M | $-7M | |
| Stock Issued | · | · | · | · | · | · | $4M | $4M | $4M | $8M | $0 | · | · | · | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | $4M | · | · | · | · | · | · | · | |
| Financing Cash Flow | $4M | $13M | $2M | $0 | $20M | $6M | $12M | $4M | $4M | $9M | $0 | $9M | $7.4K | $0 | $0 | $0 | |
| Net Change in Cash | $-5M | $4M | $-2M | $-5M | $12M | $-2M | $9M | $860.8K | $-3M | $-600.2K | $-9M | $-1M | $-12M | $-4M | $-4M | $-7M |
Profitability 3
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -81.9% | · | -46.0% | -46.9% | -32.0% | · | -102.8% | -36.0% | -6.4% | · | -68.9% | -32.1% | -28.3% | · | -19.0% | -20.3% | |
| ROE | -129.6% | · | -71.8% | -75.0% | -53.5% | · | -184.2% | -52.9% | -12.7% | · | -80.4% | -34.1% | -31.3% | · | -19.9% | -20.8% | |
| ROIC | · | · | · | · | · | · | -62.1% | 443.4% | 232.8% | · | -223.2% | -47.0% | -49.5% | · | · | -24.9% |
Liquidity & Solvency 2
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | · | · | · | · | · | · | · | 1.6 | · | 2.9 | 11.0 | 4.7 | · | 12.9 | 28.1 | |
| Quick Ratio | 1.1 | · | 4.1 | 6.1 | 8.9 | · | 2.3 | 1.0 | 0.6 | · | 1.8 | 7.6 | 3.1 | · | 12.7 | 27.7 |
Efficiency 1
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | · | 0.0 | · | · | · | 0.0 | · | · | · | 0.0 | · | · | · |
Valuation (TTM) 7
| Metric | Trend | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-37M | · | $-32M | $-29M | $-24M | · | $-33M | $-30M | $-35M | · | $-40M | $-32M | $-27M | · | $-20M | $-17M | |
| Market Cap | $64M | · | $42M | $42M | $29M | · | $107M | $68M | $131M | · | $86M | $129M | $127M | · | $112M | $93M | |
| P/E | -1.4 | · | -1.0 | -1.1 | -0.6 | · | -2.1 | -1.5 | -2.7 | · | -2.1 | -3.9 | -4.8 | · | -5.5 | -5.5 | |
| P/B | 20.4 | · | 3.2 | 2.3 | 1.2 | · | 15.2 | -38.6 | -39.1 | · | 12.8 | 6.2 | 6.3 | · | 3.7 | 2.6 | |
| P / Tangible Book | 20.4 | · | 3.2 | 2.3 | 1.2 | · | 15.2 | · | · | · | 12.8 | 6.2 | 6.3 | · | 3.7 | 2.6 | |
| P / Cash Flow | -7.1 | · | · | · | -3.6 | · | · | · | -18.6 | · | · | · | -10.9 | · | · | · | |
| Earnings Yield | -73.5% | · | -95.7% | -94.5% | -163.3% | · | -46.7% | -67.0% | -37.7% | · | -48.0% | -25.6% | -21.0% | · | -18.3% | -18.2% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2022-09-30 | |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | — |
| Net Income | $-29M | $-25M | $-56M | $-25M | — |
| Diluted EPS | $-1.40 | $-2.31 | $-6.23 | $-3.10 | — |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2022-09-30 | |
|---|---|---|---|---|---|
| Current Ratio | — | — | 2.4 | 4.7 | — |
| Quick Ratio | 5.4 | 2.7 | 1.3 | 3.7 | — |
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