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CRBU NASDAQ US

Caribou Biosciences, Inc. - Common Stock

Healthcare · Biotechnology Website · IPO Jul 2021
$1.94
▼ $-0.05 (-2.51%)
Vol 1.1M
4
Quality Score
fail
Mkt Cap
$148.6M
ROE
-80.8%
Margin
-1690.5%
D/E
0.00
Beta
2.68
52W
$1–$4

Wall Street Consensus

15 analysts · Apr 2026
5
Strong Buy
9
Buy
1
Hold
0
Sell
0
Strong Sell
93.3%
Buy Rating

Price Chart

Earnings

Beat rate: 75.0%
Quarter EPS Est EPS Act Surprise
Dec 2025 $-0.32 $-0.28 +$0.04
Sep 2025 $-0.37 $-0.30 +$0.07
Jun 2025 $-0.40 $-0.58 $-0.18
Mar 2025 $-0.45 $-0.43 +$0.02

Quarterly Revenue & Earnings

Quarter 2024-0… 2024-1… 2025-0… 2025-0… 2025-0… 2025-1…
Revenue $2.1M $2.4M $2.7M $2.2M $3.9M
Net Income -$35.5M -$40.0M -$54.1M -$27.5M -$26.5M

Fundamentals Trend

Metric 2025-06-30 2025-09-02 2025-10-02 2025-11-03 2025-12-03 2026-01-02
ROE (TTM) -71.6% -71.6% -71.6% -71.6% -80.8% -80.8%
P/E (TTM)
Net Margin -2028.4% -1800.9% -1800.9% -1800.9% -1690.5% -1690.5%
Gross Margin
D/E Ratio 0.00 0.00 0.00 0.00 0.00 0.00
Current Ratio 6.66 6.66 6.66 6.66 5.54 5.54

Key Ratios

ROA (TTM)
-62.7%
P/S (TTM)
15.99
P/B
0.6
EPS (TTM)
$-1.70
CF/Share
$-1.36
Rev Growth 3Y
+1.4%
52W High
$3.54
52W Low
$0.66
$0.66 52-Week Range $3.54

Financial Health

Free Cash Flow
-$20.6M
Net Debt
$14.9M
Cash
$12.4M
Total Debt
$27.2M
As of Dec 31, 2025

How does CRBU compare to Biotechnology peers?

Peer group: Micro-cap Biotechnology (All) · 528 companies

CRBU AAPG ABEO ABOS ABP

CRBU valuation vs Biotechnology peers

P/E ratio
0% below peers (18.8)
vs Peers
vs Industry
Undervalued
P/S ratio
16.0
24% above peers (12.9)
vs Peers
vs Industry
Pricier
P/B ratio
0.6
77% below peers (2.5)
vs Peers
vs Industry
Undervalued
Div yield
0% below peers (0.0%)
vs Peers
vs Industry
Low yield

CRBU profitability vs Biotechnology peers

ROE
-80.8%
20% below peers (-67.3%)
vs Peers
vs Industry
Below avg
Net margin
-1690.5%
490% below peers (-286.8%)
vs Peers
vs Industry
Weak
Gross margin
0% below peers (78.6%)
vs Peers
vs Industry
In line
ROA
-62.7%
34% below peers (-46.7%)
vs Peers
vs Industry
Weak

CRBU financial health vs Biotechnology peers

D/E ratio
0.0
0% below peers (0.0)
vs Peers
vs Industry
Low debt
Current ratio
5.5
25% above peers (4.4)
vs Peers
vs Industry
Below avg
Beta
2.7
177% above peers (1.0)
vs Peers
vs Industry
More volatile

CRBU fundamentals radar

CRBU Peer median Industry

CRBU profitability vs leverage

Bubble size = market cap · X = net margin · Y = D/E ratio

CRBU vs peers: key metrics

Insider Activity

Neutral
Buys
0
Sells
0
KELLY TIMOTHY P
Chief Technology Officer · Feb 25
6228 shs
MCCLUNG BARBARA G
Officer · Feb 24
6938 shs
KELLY TIMOTHY P
Chief Technology Officer · Feb 24
3147 shs
KHAN RUHI AHMAD
Officer · Feb 24
6938 shs
ALBERTSON TINA M.
Officer · Feb 24
1066 shs
MCCLUNG BARBARA G
Officer · Feb 20
45000 shs
HAURWITZ RACHEL E. PH.D.
Chief Executive Officer · Feb 20
151700 shs
KELLY TIMOTHY P
Chief Technology Officer · Feb 20
45000 shs
RYALI SRIRAM
Chief Financial Officer · Feb 20
55000 shs
KHAN RUHI AHMAD
Officer · Feb 20
45000 shs
Last 90 days

Top Holders

Top 5: 15.81%
Pfizer Inc
4.85%
$8.3M
Vanguard Group Inc
4.45%
$7.7M
Kynam Capital Management, LP
2.59%
$4.5M
Blackrock Inc.
2.22%
$3.8M
Renaissance Technologies, L…
1.70%
$2.9M
As of Dec 31, 2025

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