PLYX Polaryx Therapeutics, Inc. - Common Stock

NASDAQ · · View on SEC EDGAR ↗
$2.03
Price · Aug 19, 2026
Fundamentals as of Aug 13, 2026
52W Range
$2–$49
0% of range
Analyst Rating
BUY
9 analysts
Price Target
$8
+269% upside
P/E (TTM)
—
ROE
-193.7%
Net Profit Margin
—

PLYX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$2.03
Market Cap
—
P/E (TTM)
—
EPS (TTM)
$-0.20
Revenue (TTM)
—
Div Yield
—
ROE
-193.7%
Debt/Equity
—
52W Range
$2 – $49

PLYX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income —
EPS $-0.20
2-point trend, +77.5%
2024-12-31 → 2025-12-31
Free Cash Flow —
Margins —

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
PLYX
Peer Median

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
PLYX
Peer Median
ROA
-176.7%
—
ROE
-193.7%
—

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
PLYX
Peer Median
Current Ratio
8.5
—
Quick Ratio
8.5
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
PLYX
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
PLYX
Peer Median
EPS (Diluted)
2-point trend, +77.5%
$-0.20
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
PLYX
Peer Median

PLYX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 9 analysts
  • Strong Buy 2 22.2%
  • Buy 6 66.7%
  • Hold 1 11.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

4 analysts · 2026-08-14
Median target $7.00 +244.8%
Mean target $7.50 +269.5%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PLYX — — — — -193.7% —
NTHI — -2.6 -51.8% — — —
CPIX $60M -20.9 17.6% -6.4% -11.9% —
RANI — -3.0 58.9% -1817.1% -169.6% —
RFL — -1.6 44.0% -3328.2% -34.6% —
CGTX $120M -4.2 — — -113.7% —
VRCA $143M -4.9 370.2% -50.3% -492.8% —
LONA $71M -0.3 — — -353.4% —
LLY — 46.8 44.7% 31.7% 101.2% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 11
Annual Income Statement data for PLYX
Metric Trend 20252024
R&D Expense 2-point trend, +122.9% $6M $3M
SG&A Expense 2-point trend, +0.9% $2M $2M
Operating Expenses 2-point trend, +79.7% $8M $4M
Operating Income 2-point trend, -79.7% $-8M $-4M
Pretax Income 2-point trend, +70.4% $-9M $-30M
Net Income 2-point trend, +70.4% $-9M $-30M
EPS (Basic) 2-point trend, +77.5% $-0.20 $-0.89
EPS (Diluted) 2-point trend, +77.5% $-0.20 $-0.89
Shares (Basic) 2-point trend, +32.8% 45,422,581 34,200,660
Shares (Diluted) 2-point trend, +32.8% 45,422,581 34,200,660
EBITDA $-8M ·
Balance Sheet 15
Annual Balance Sheet data for PLYX
Metric Trend 20252024
Cash & Equivalents 2-point trend, +11.3% $5M $5M
Prepaid Expense · $380.0K
Other Current Assets $27.0K ·
Current Assets 2-point trend, +3.4% $5M $5M
Total Assets 2-point trend, +3.4% $5M $5M
Accounts Payable 2-point trend, +552.8% $470.0K $72.0K
Accrued Liabilities $23.0K ·
Current Liabilities 2-point trend, +109.3% $605.0K $289.0K
Total Liabilities 2-point trend, +109.3% $605.0K $289.0K
Common Stock 2-point trend, +25.0% $5.0K $4.0K
Paid-in Capital 2-point trend, +9.3% $104M $95M
Retained Earnings 2-point trend, -9.9% $-100M $-91M
Stockholders' Equity 2-point trend, -3.1% $5M $5M
Liabilities + Equity 2-point trend, +3.4% $5M $5M
Shares Outstanding 2-point trend, +15.0% 47,343,297 41,151,571
Cash Flow 5
Annual Cash Flow data for PLYX
Metric Trend 20252024
Stock-based Comp 2-point trend, +96.9% $5M $2M
Operating Cash Flow 2-point trend, -53.3% $-4M $-3M
Stock Issued 2-point trend, -38.6% $4M $7M
Net Stock Activity $4M ·
Financing Cash Flow 2-point trend, -37.9% $4M $7M
Profitability 2
Annual Profitability data for PLYX
Metric Trend 20252024
ROA -176.7% ·
ROE -193.7% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for PLYX
Metric Trend 20252024
Current Ratio 8.5 ·
Quick Ratio 8.5 ·
Per Share 4
Annual Per Share data for PLYX
Metric Trend 20252024
Book Value / Share $0.10 ·
Cash Flow / Share $-0.09 ·
Cash / Share $0.11 ·
EPS (TTM) $-0.20 ·
Valuation (TTM) 1
Annual Valuation (TTM) data for PLYX
Metric Trend 20252024
Net Income TTM $-9M ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-31
Net Income $-9M$-30M
Diluted EPS $-0.20$-0.89
Balance Sheet
2025-12-312024-12-31
Current Ratio 8.5—
Quick Ratio 8.5—

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Institutional owners (13F) 13 filers · $5.5M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
7 5 1 2 —

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair. Change vs prior quarter not shown: filer coverage differs too much between these two quarters for a reliable comparison.

Institution Value Shares % of tracked 13F Type
VANGUARD CAPITAL MANAGEMENT LLC $4,409,940 1,657,872 80.47% Shares
GEODE CAPITAL MANAGEMENT, LLC $377,655 141,890 6.89% Shares
VANGUARD FIDUCIARY TRUST CO $279,492 105,072 5.10% Shares
STATE STREET CORP $154,557 58,104 2.82% Shares
BlackRock, Inc. $109,092 41,012 1.99% Shares
NORTHERN TRUST CORP $74,445 27,987 1.36% Shares
JANE STREET GROUP, LLC $25,331 9,523 0.46% Shares
Allworth Financial LP $20,554 7,727 0.38% Shares
Vanguard Global Advisers, LLC $16,806 6,318 0.31% Shares
Tower Research Capital LLC (TRC) $7,985 3,002 0.15% Shares
UBS Group AG $3,413 1,283 0.06% Shares
Fortitude Family Office, LLC $503 189 0.01% Shares
HRT FINANCIAL LP $218 82,094 0.00% Shares

Company insiders 1 insider · 1 officers · 1 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Michael G. Landis Chief Financial Officer Feb. 18, 2026 P 228,225 1 0 $7,999

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Mstone Partners Healthcare Limited, MBstone Biotech Flagship Limited, Mstone Pediaorphan Singapore I Pte. Limited, Alex Keun Mo Yang Feb. 5, 2026 48.00% Initial filing — SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 2 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
VXF · VANGUARD INDEX FUNDS 0.00% 142,033 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 1,468,014 SH Aug. 8, 2026 Daily