CGTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

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Price $0.93
Market Cap (MRQ) $88M
P/E -2.9
EPS $-0.32
ROE -113.7%
52W Range $1–$2

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10-Year Performance Revenue, net income, margins and EPS trends

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EPS$-0.32
2020-12-31 → 2025-12-31
Free Cash Flow·
2021-12-31 → 2024-12-31
Net margin·
2021-12-31 → 2023-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend CGTX 5Y avg Peer Median Verdict
P/E -2.95Y avg ≈-2.3 ≈-2.3 · ·
P/S -2937.35Y avg ≈-2064.1 ≈-2064.1 · ·
P/B (MRQ) 2.75Y avg ≈2.5 ≈2.5 3.6 Fair value
Price / Cash Flow -3.35Y avg ≈-10.4 ≈-10.4 · ·
Price / Tangible Book 2.45Y avg ≈2.5 ≈2.5 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise 15.3%
Next Report Nov 04, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 11, 2026 $-0.04 $-0.06 38.1%
March 31, 2026 May 13, 2026 $-0.05 $-0.07 27.4%
Dec. 31, 2025 $-0.05 $-0.09 43.5%
Sept. 30, 2025 $-0.06 $-0.10 41.2%
June 30, 2025 $-0.11 $-0.11 -1.1%
March 31, 2025 $-0.14 $-0.11 -24.4%
Dec. 31, 2024 $-0.17 $-0.14 -17.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 12
Metric Trend 202520242023202220212020
R&D Expense $37M$42M$37M$30M$19M$13M
SG&A Expense $11M$12M$14M$13M$10M$5M
Operating Expenses $48M$54M$51M$44M$29M$17M
Operating Income $-48M$-54M$-51M$-44M$-29M$-17M
Other Non-op $24M$20M$25M$22M$17M$10M
Income Tax $0$0$0$0$0·
Net Income $-23M$-34M$-26M$-21M$-12M$-8M
EPS (Basic) $-0.32$-0.86$-0.86$-0.91$-3.13$-23.76
EPS (Diluted) $-0.32$-0.86$-0.86$-0.91$-3.13$-23.76
Shares (Basic) 72,766,98339,730,14830,029,08723,640,1995,190,883508,112
Shares (Diluted) 72,766,98339,730,14830,029,08723,640,1995,190,883508,112
EBITDA $-48M$-54M$-51M$-43M$-29M·
Balance Sheet 22
Metric Trend 202520242023202220212020
Cash & Equivalents $37M$25M$30M$42M$55M$5M
Prepaid Expense $1M$2M$3M$2M$2M$544.0K
Other Current Assets ····$11.0K$23.0K
Current Assets $48M$30M$34M$48M$59M$7M
PP&E (Net) $93.0K$181.0K$284.0K$233.0K$145.0K$211.0K
PP&E (Gross) $280.0K$1M$1M$1M$1M$988.0K
Accum. Depreciation $187.0K$1M$1M$953.0K$870.0K$777.0K
Total Assets $48M$30M$35M$50M$59M$7M
Accounts Payable $1M$2M$4M$3M$4M$2M
Accrued Liabilities $12M$8M$4M$2M$2M$994.0K
Current Liabilities $14M$11M$10M$8M$8M$3M
Capital Leases $195.0K$342.0K$520.0K$695.0K··
Deferred Tax $67.0K$110.0K$147.0K$178.0K$13.0K$22.0K
Other Non-current Liabilities ··$0$2M$0·
Total Liabilities $14M$11M$11M$10M$8M$20M
Common Stock $90.0K$60.0K$32.0K$29.0K$22.0K$1.0K
Paid-in Capital $233M$194M$166M$156M$145M$222.0K
Retained Earnings $-199M$-175M$-141M$-115M$-94M$-68M
AOCI ··$-195.0K$-199.0K$-198.0K$-187.0K
Stockholders' Equity $34M$19M$24M$40M$51M$-68M
Liabilities + Equity $48M$30M$35M$50M$59M$7M
Shares Outstanding 88,904,16159,854,87732,165,47828,991,54822,230,032538,793
Cash Flow 10
Metric Trend 202520242023202220212020
D&A $36.0K$107.0K$96.0K$83.0K$93.0K$98.0K
Stock-based Comp $2M$4M$4M$4M$5M$475.0K
Deferred Tax ·$0$0$0··
Other Non-cash $-3M$2M$5M$-791.0K$3M·
Operating Cash Flow $-25M$-28M$-16M$-19M$-4M$-3M
CapEx ·$4.0K$147.0K$171.0K$27.0K$10.0K
Investing Cash Flow $9.0K$-4.0K$-147.0K$-171.0K$-27.0K$-10.0K
Financing Cash Flow $37M$24M$5M$6M$53M$6M
Net Change in Cash $12M$-5M$-12M$-13M$50M$2M
Free Cash Flow ·$-28M$-16M$-19M$-4M·
Profitability 5
Metric Trend 202520242023202220212020
Operating Margin ··187866.7%155539.3%3202.5%·
Net Margin ··95511.1%76417.9%1312.0%·
EBITDA Margin ··187511.1%155242.9%3192.1%·
ROA -59.8%-103.9%-60.3%-39.1%-35.4%·
ROE -113.7%-204.5%-96.6%-53.8%66.1%·
Liquidity & Solvency 2
Metric Trend 202520242023202220212020
Current Ratio 3.42.73.46.17.5·
Quick Ratio 2.62.22.95.37.0·
Efficiency 1
Metric Trend 202520242023202220212020
Asset Turnover ··-0.0-0.0-0.0·
Per Share 5
Metric Trend 202520242023202220212020
Book Value / Share $0.39$0.31$0.76$1.39$2.31·
Revenue / Share ··$-0.00$-0.00$-0.17·
Cash Flow / Share $-0.34$-0.72$-0.53$-0.78$-0.70·
Cash / Share $0.41$0.42$0.93$1.43$2.46·
EPS (TTM) $-0.32$-0.86$-0.86$-0.91$-3.13·
Valuation (TTM) 10
Metric Trend 202520242023202220212020
Revenue TTM $-28.0K$-28.0K$-27.0K$-28.0K$-893.0K·
Net Income TTM $-23M$-34M$-26M$-21M$-12M·
Market Cap $120M$42M$60M$61M$140M·
P/E -4.2-0.8-2.2-2.3-2.0·
P/S -4286.5-1498.5-2203.9-2174.4-157.3·
P/B 3.52.22.41.52.7·
P / Tangible Book 3.52.22.41.52.7·
P / Cash Flow -4.9-1.5-3.7-3.3-38.7·
P / FCF ·-1.5-3.7-3.3-38.4·
Earnings Yield -23.7%-122.7%-46.5%-43.3%-49.5%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Operating Margin % · · 187866.7% 155539.3% 3202.5%
Net Income $-23M $-34M $-26M $-21M $-12M
Diluted EPS $-0.32 $-0.86 $-0.86 $-0.91 $-3.13

Institutional owners (13F) 69 filers · $30.4M total · As of Sept. 30, 2026

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Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 69
Value held $30.4M
New positions 3
Exited positions 13
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
3 (-11 vs prior Q) 13 (+1 vs prior Q) 23 (+6 vs prior Q) 10 (-3 vs prior Q) +1.2M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BIOS Capital Management, LP $6,900,001 6,000,000 22.71% Shares
DAVENPORT & Co LLC $4,898,438 4,259,511 16.12% Shares
VANGUARD GROUP INC $4,478,658 3,317,525 14.74% Shares
VANGUARD CAPITAL MANAGEMENT LLC $3,954,591 3,438,775 13.02% Shares
BlackRock, Inc. $1,451,292 1,261,993 4.78% Shares
Chescapmanager LLC $1,146,583 997,029 3.77% Shares
GEODE CAPITAL MANAGEMENT, LLC $1,047,051 910,006 3.45% Shares
RENAISSANCE TECHNOLOGIES LLC $797,281 693,288 2.62% Shares
Hilton Capital Management, LLC $631,293 548,950 2.08% Shares
VANGUARD FIDUCIARY TRUST CO $584,453 508,220 1.92% Shares
CM Management, LLC $517,500 450,000 1.70% Shares
Dauntless Investment Group, LLC $427,456 371,701 1.41% Shares
Sigma Planning Corp $416,605 362,265 1.37% Shares
STATE STREET CORP $401,330 348,983 1.32% Shares
TOCQUEVILLE ASSET MANAGEMENT L.P. $368,575 320,500 1.21% Shares
UBS Group AG $251,316 218,536 0.83% Shares
AMERICAN FINANCIAL GROUP INC $235,750 205,000 0.78% Shares
NORTHERN TRUST CORP $204,932 178,202 0.67% Shares
Voss Capital, LP $201,250 175,000 0.66% Shares
Texas Capital Bank Wealth Management Services Inc $164,790 143,296 0.54% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $97,681 84,940 0.32% Shares
XTX Topco Ltd $90,242 78,471 0.30% Shares
Corient Private Wealth LP $89,960 78,226 0.30% Shares
McAdam, LLC $74,236 64,553 0.24% Shares
FCA CORP /TX $60,416 52,536 0.20% Shares
RAYMOND JAMES FINANCIAL INC $58,478 50,850 0.19% Shares
Circle Wealth Management, LLC $56,168 48,842 0.18% Shares
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management $55,200 48,000 0.18% Shares
Bangor Savings Bank $46,597 40,519 0.15% Shares
Essex Financial Services, Inc. $46,000 40,000 0.15% Shares
JONES FINANCIAL COMPANIES LLLP $45,521 40,644 0.15% Shares
GABELLI FUNDS LLC $34,500 30,000 0.11% Shares
Bryn Mawr Trust Advisors, LLC $33,408 29,050 0.11% Shares
MORGAN STANLEY $32,054 27,873 0.11% Shares
HighTower Advisors, LLC $30,475 26,500 0.10% Shares
PRIVATE MANAGEMENT GROUP INC $27,600 24,000 0.09% Shares
Vanguard Global Advisers, LLC $27,187 23,641 0.09% Shares
CWA Asset Management Group, LLC $26,450 23,000 0.09% Shares
Creative Planning $25,530 22,200 0.08% Shares
Qube Research & Technologies Ltd $25,070 21,800 0.08% Shares
GAMCO INVESTORS, INC. ET AL $23,000 20,000 0.08% Shares
Cetera Investment Advisers $22,828 19,850 0.08% Shares
Rockefeller Capital Management L.P. $22,116 19,231 0.07% Shares
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $20,087 17,467 0.07% Shares
Focus Partners Wealth $19,838 17,250 0.07% Shares
Northeast Financial Consultants Inc $19,627 63,351 0.06% Shares
MERCER GLOBAL ADVISORS INC /ADV $18,344 15,951 0.06% Shares
CITIZENS FINANCIAL GROUP INC/RI $15,731 13,679 0.05% Shares
Bank of New York Mellon Corp $15,481 13,462 0.05% Shares
BRADLEY FOSTER & SARGENT INC/CT $13,480 11,722 0.04% Shares

Show all 69 institutional owners →

Activists & 5%+ owners 1 position

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Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 13 insiders · 4 officers · 7 directors

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Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Lisa Ricciardi CEO & President April 16, 2026 P 1,715,851 1 0 $10,092
John Brendan Doyle Chief Financial Officer May 1, 2026 F 618,942 1 0 $11,300
James Michael O'Brien Chief Financial Officer March 23, 2022 A 5,000 0 0 $0
Anthony Caggiano Chief Medical Officer April 16, 2026 P 874,906 1 0 $11,100
Peggy Wallace Director June 17, 2026 A 111,461 0 0 $0
Jack A. Khattar Director June 17, 2026 A 73,500 0 0 $0
Brett P Monia Director June 17, 2026 A 73,500 0 0 $0
Ellen B Richstone Director June 17, 2026 A 83,500 0 0 $0
Fletcher Aaron G.L. Director Sept. 19, 2025 M 56,229 0 0 $0
Mark H. Breedlove Director Oct. 13, 2021 X 404,439 0 0 $0
Golden Seeds Cognition Therapeutics LLC 10% owner Sept. 27, 2022 J 0 0 0 $0
Ogden CAP Associates, LLC 10% owner Oct. 13, 2021 X 2,210,377 0 0 $0
BIOS MEMORY SPV I, LP 10% owner Oct. 13, 2021 C 60,065 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 4 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IBRN · iShares Trust 0.08% 6,057 SH Sept. 11, 2026 Daily
IWC · iShares Trust 0.02% 273,424 SH Sept. 10, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 923,898 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,444,295 SH Aug. 19, 2026 Daily

CGTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

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rating · 9 analysts BUY
Median target $3.00 +224.3%
2 22.2% Strong Buy
6 66.7% Buy
1 11.1% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

3 analysts · 2026-10-03

Mean target $3.33 +260.3%

← Below all targets Current price $0.93
Low$3.00 Mean$3.33 High$4.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

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FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CGTX $120M -4.2 · · -113.7% ·
PLYX · · · · -193.7% ·
NMRA $312M -1.2 · · -165.2% ·
NTRB · · · · · ·
NTHI · -2.6 -51.8% · · ·
VRCA $143M -4.9 370.2% -50.3% -492.8% ·
TELO $46M -4.0 · · -325.7% ·
RFL · -1.6 44.0% -3328.2% -34.6% ·
CING · · · · · ·
PLRX $75M -0.5 -83.7% · -74.4% ·
ELOX · · · · 30.1% ·

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Source: SEC 10-Q filed Aug 7, 2026