PTGX
NASDAQ
US
Protagonist Therapeutics, Inc. - Common Stock
$103.78
▲ +$0.11
(+0.11%)
Vol 602K
9
Quality Score
ok
Deep Check
1/5
fail
Rev ✓
NI ✗
>IPO ✗
Mkt Cap
$5.5B
P/E
118.9
ROE
6.9%
Margin
21.9%
D/E
0.00
Beta
2.25
52W
$34–$97
Wall Street Consensus
19 analysts · Apr 20266
Strong Buy
11
Buy
2
Hold
0
Sell
0
Strong Sell
89.5%
Buy Rating
Price Chart
Similar Stocks
Earnings
Beat rate: 75.0%| Quarter | EPS Est | EPS Act | Surprise |
|---|---|---|---|
| Dec 2025 | $-0.50 | $-0.69 | $-0.19 |
| Sep 2025 | $-0.65 | $-0.62 | +$0.03 |
| Jun 2025 | $-0.59 | $-0.55 | +$0.04 |
| Mar 2025 | $-0.24 | $-0.19 | +$0.05 |
Fundamentals Trend
| Metric | 2025-06-30 | 2025-09-02 | 2025-10-02 | 2025-11-03 | 2025-12-03 | 2026-01-02 |
|---|---|---|---|---|---|---|
| ROE (TTM) | 8.1% | 8.1% | 8.1% | 8.1% | 6.9% | 6.9% |
| P/E (TTM) | 65.83 | 67.07 | 77.61 | 93.99 | 115.90 | 118.93 |
| Net Margin | -627.0% | 24.9% | 24.9% | 24.9% | 21.9% | 21.9% |
| Gross Margin | — | — | — | — | — | — |
| D/E Ratio | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Current Ratio | 16.97 | 16.97 | 16.97 | 16.97 | 13.05 | 13.05 |
Key Ratios
ROA (TTM)
6.3%
P/S (TTM)
26.10
P/B
3.4
EPS (TTM)
$0.63
CF/Share
$-2.59
Rev Growth 3Y
+151.3%
52W High
$96.54
52W Low
$33.70
$33.70
52-Week Range
$96.54
How does PTGX compare to Biotechnology peers?
Peer group: Micro-cap Biotechnology (All) · 528 companies
PTGX valuation vs Biotechnology peers
P/E ratio
118.9
▲
533%
above
peers
(18.8)
vs Peers
vs Industry
Undervalued
P/S ratio
26.1
▲
103%
above
peers
(12.9)
vs Peers
vs Industry
Pricier
P/B ratio
3.4
▲
37%
above
peers
(2.5)
vs Peers
vs Industry
Pricier
Div yield
—
▼
0%
below
peers
(0.0%)
vs Peers
vs Industry
Low yield
PTGX profitability vs Biotechnology peers
ROE
6.9%
▲
110%
above
peers
(-67.3%)
vs Peers
vs Industry
Top tier
Net margin
21.9%
▲
108%
above
peers
(-286.8%)
vs Peers
vs Industry
Below avg
Gross margin
—
▼
0%
below
peers
(78.6%)
vs Peers
vs Industry
In line
ROA
6.3%
▲
114%
above
peers
(-46.7%)
vs Peers
vs Industry
Top tier
PTGX financial health vs Biotechnology peers
D/E ratio
0.0
▼
0%
below
peers
(0.0)
vs Peers
vs Industry
Low debt
Current ratio
13.1
▲
194%
above
peers
(4.4)
vs Peers
vs Industry
Strong liquidity
Beta
2.3
▲
132%
above
peers
(1.0)
vs Peers
vs Industry
More volatile
PTGX fundamentals radar
PTGX
Peer median
Industry
PTGX profitability vs leverage
Bubble size = market cap · X = net margin · Y = D/E ratio