RNA Avidity Biosciences, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$12.90
Price · Aug 18, 2026
Fundamentals as of Feb 23, 2026

RNA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$12.90
Market Cap
$1.95B
P/E (TTM)
-2.6
EPS (TTM)
$-4.97
Revenue (TTM)
$19M
Div Yield
ROE
-47.5%
Debt/Equity
52W Range
$11 – $73

RNA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $19M
8-point trend, +4848.5%
2018-12-31 2025-12-31
EPS $-4.97
6-point trend, -142.4%
2020-12-31 2025-12-31
Free Cash Flow $-664M
6-point trend, -1637.2%
2020-12-31 2025-12-31
Margins -3650.4%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
RNA
Peer Median
P/E (TTM)
5-point trend, -74.0%
-2.6
P/S (TTM)
5-point trend, +377.8%
104.0
9.5
P/B
5-point trend, +117.0%
1.2
1.1
Price / FCF
5-point trend, -42.7%
-2.9

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
RNA
Peer Median
Operating Margin
5-point trend, -214.2%
-3977.3%
Net Profit Margin
5-point trend, -188.5%
-3650.4%
-348.2%
ROA
5-point trend, -25.5%
-38.9%
-40.7%
ROE
5-point trend, -56.3%
-47.5%
-49.8%
ROIC
-44.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
RNA
Peer Median
Current Ratio
5-point trend, -33.6%
9.2
12.1
Quick Ratio
5-point trend, -85.7%
2.0

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
RNA
Peer Median
Revenue YoY
5-point trend, +101.1%
72.1%
Revenue CAGR 3Y
5-point trend, +101.1%
26.7%
Revenue CAGR 5Y
5-point trend, +101.1%
22.5%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
RNA
Peer Median
EPS (Diluted)
5-point trend, -74.4%
$-4.97

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
RNA
Peer Median

RNA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 7 analysts
  • Strong Buy 2 28.6%
  • Buy 4 57.1%
  • Hold 1 14.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

4 analysts · 2026-08-19
Median target $25.00 +93.8%
Mean target $25.00 +93.8%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.09%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.97 $-1.06 0.09%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
RNA $10.91B -14.5 72.1% -3650.4% -47.5%
EBS $644M 13.3 -28.8% 7.1% 9.9%
ARCT $174M -2.6 -46.1% -80.2% -29.6%
NBP
IMUX -0.9
ORGO $658M 34.5 17.0% 6.6% 13.9%
NERV $174M -0.1 339.5%
IVVD $697M -8.2 110.5% -98.2% -36.9%
TNXP $200M -1.1 29.8% -946.2% -60.0%
WHWK $114M -7.3 -72.5% -288.3% -13.4%
PEPG $448M -3.1 -82.0%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for RNA
Metric Trend 2025202420232022202120202019
Revenue 7-point trend, +708.8% $19M $11M $10M $9M $9M $7M $2M
R&D Expense 7-point trend, +3745.9% $559M $304M $191M $150M $101M $38M $15M
SG&A Expense 7-point trend, +3920.7% $206M $86M $54M $38M $26M $13M $5M
Operating Expenses 7-point trend, +3791.4% $765M $390M $245M $188M $127M $51M $20M
Operating Income 7-point trend, -4203.8% $-746M $-379M $-236M $-179M $-118M $-44M $-17M
Interest Expense 4-point trend, -100.0% · · · $0 $0 $209.0K $7M
Other Non-op 7-point trend, -1943000.00 $-2M $-248.0K $-594.0K $-57.0K $-62.0K $-75.0K $0
Pretax Income 3-point trend, -222.6% $-685M $-322M $-212M · · · ·
Income Tax Flat — no change across 7 periods $0 $0 $0 $0 $0 $0 $0
Net Income 7-point trend, -2668.0% $-685M $-322M $-212M $-174M $-118M $-44M $-25M
EPS (Basic) 6-point trend, -142.4% $-4.97 $-2.89 $-2.91 $-3.34 $-2.85 $-2.05 ·
EPS (Diluted) 6-point trend, -142.4% $-4.97 $-2.89 $-2.91 $-3.34 $-2.85 $-2.05 ·
Shares (Basic) 6-point trend, +535.7% 137,710,000 111,582,000 73,012,000 52,162,000 41,428,000 21,663,000 ·
Shares (Diluted) 6-point trend, +535.7% 137,710,000 111,582,000 73,012,000 52,162,000 41,428,000 21,663,000 ·
EBITDA 6-point trend, -1584.7% $-746M $-379M $-236M $-179M $-118M $-44M ·
Balance Sheet 24
Annual Balance Sheet data for RNA
Metric Trend 2025202420232022202120202019
Cash & Equivalents 7-point trend, +304.4% $383M $220M $185M $340M $320M $321M $95M
Short-term Investments 2-point trend, +1174.1% · · · · $85M $7M ·
Receivables 3-point trend, -100.0% · $0 $1M $2M · · ·
Prepaid Expense 5-point trend, +1714.9% $102M $41M $16M $12M $6M · ·
Other Current Assets 3-point trend, +3388.0% $53M $19M · $2M · · ·
Current Assets 7-point trend, +1779.7% $1.80B $1.54B $611M $623M $411M $332M $96M
PP&E (Net) 7-point trend, +3597.8% $23M $13M $8M $6M $5M $1M $631.0K
PP&E (Gross) 7-point trend, +1444.2% $35M $21M $14M $9M $7M $3M $2M
Accum. Depreciation 7-point trend, +617.0% $12M $8M $5M $3M $2M $2M $2M
Other Non-current Assets 7-point trend, +13595.8% $82M $521.0K $301.0K $598.0K $599.0K $47.0K $600.0K
Total Assets 7-point trend, +1920.5% $1.96B $1.56B $629M $639M $428M $334M $97M
Accounts Payable 7-point trend, +437.4% $12M $8M $9M $5M $3M $8M $2M
Current Liabilities 7-point trend, +1809.4% $195M $98M $81M $52M $30M $15M $10M
Capital Leases 7-point trend, +11430.0% $45M $3M $6M $8M $10M $938.0K $393.0K
Other Non-current Liabilities · · · · · · $45.0K
Total Liabilities 7-point trend, +878.3% $269M $139M $128M $61M $46M $28M $28M
Long-term Debt · · · · · · $5M
Common Stock 7-point trend, +15000.00 $15.0K $12.0K $8.0K $7.0K $5.0K $4.0K $0
Paid-in Capital 4-point trend, +2275.7% · · · $939M $566M $373M $-43M
Retained Earnings 7-point trend, -7011.5% $-1.58B $-893M $-571M $-359M $-185M $-67M $-22M
AOCI 6-point trend, +51340.0% $3M $3M $125.0K $-3M $-187.0K $-5.0K ·
Stockholders' Equity 7-point trend, +2683.7% $1.69B $1.42B $501M $578M $381M $306M $-65M
Liabilities + Equity 7-point trend, +1920.5% $1.96B $1.56B $629M $639M $428M $334M $97M
Shares Outstanding 7-point trend, +4958.7% 151,205,000 119,893,000 79,275,000 69,768,000 47,754,000 37,569,000 2,989,000
Cash Flow 10
Annual Cash Flow data for RNA
Metric Trend 2025202420232022202120202019
Stock-based Comp 7-point trend, +23998.0% $98M $51M $38M $27M $17M $4M $406.0K
Operating Cash Flow 7-point trend, -26222.1% $-650M $-301M $-119M $-136M $-95M $-37M $2M
CapEx 7-point trend, +5567.7% $13M $7M $4M $3M $4M $1M $235.0K
Investing Cash Flow 7-point trend, -16085.1% $-38M $-854M $-130M $-190M $-83M $-8M $-235.0K
Net Debt Issued 3-point trend, +100.0% · · · $0 $0 $-5M ·
Stock Issued 6-point trend, +205.4% $837M $762M $61M $345M $175M $274M ·
Net Stock Activity 5-point trend, +4169.8% $837M $762M $61M $345M $20M · ·
Financing Cash Flow 7-point trend, +853.7% $851M $1.19B $94M $346M $176M $272M $89M
Net Change in Cash 7-point trend, +77.8% $163M $37M $-155M $20M $-1M $227M $91M
Free Cash Flow 6-point trend, -1637.2% $-664M $-308M $-123M $-139M $-99M $-38M ·
Profitability 7
Annual Profitability data for RNA
Metric Trend 2025202420232022202120202019
Operating Margin 6-point trend, -509.7% -3977.3% -3477.4% -2464.4% -1939.6% -1265.8% -652.4% ·
Net Margin 6-point trend, -458.6% -3650.4% -2957.7% -2219.9% -1886.3% -1265.4% -653.5% ·
Pretax Margin -3650.4% · · · · · ·
EBITDA Margin 6-point trend, -509.7% -3977.3% -3477.4% -2464.4% -1939.6% -1265.8% -652.4% ·
ROA 6-point trend, -88.8% -38.9% -29.4% -33.5% -32.6% -31.0% -20.6% ·
ROE 6-point trend, -235.6% -47.5% -22.0% -41.7% -36.4% -30.4% -14.2% ·
ROIC -44.2% · · · · · ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for RNA
Metric Trend 2025202420232022202120202019
Current Ratio 6-point trend, -59.5% 9.2 15.7 7.6 12.0 13.9 22.7 ·
Quick Ratio 6-point trend, -91.3% 2.0 2.2 2.3 6.6 13.7 22.5 ·
Interest Coverage · · · · · -211.9 ·
Efficiency 2
Annual Efficiency data for RNA
Metric Trend 2025202420232022202120202019
Asset Turnover 6-point trend, -66.0% 0.0 0.0 0.0 0.0 0.0 0.0 ·
Receivables Turnover 2-point trend, +257.8% · 19.7 5.5 · · · ·
Per Share 5
Annual Per Share data for RNA
Metric Trend 2025202420232022202120202019
Book Value / Share 6-point trend, +37.0% $11.17 $11.89 $6.32 $8.29 $7.99 $8.15 ·
Revenue / Share 4-point trend, -23.0% $0.14 $0.10 $0.13 $0.18 · · ·
Cash Flow / Share 4-point trend, -80.8% $-4.72 $-2.70 $-1.63 $-2.61 · · ·
Cash / Share 6-point trend, -70.4% $2.53 $1.83 $2.33 $4.88 $6.71 $8.56 ·
EPS (TTM) 6-point trend, -142.4% $-4.97 $-2.89 $-2.91 $-3.34 $-2.85 $-2.05 ·
Growth Rates 3
Annual Growth Rates data for RNA
Metric Trend 2025202420232022202120202019
Revenue YoY 5-point trend, +92.8% 72.1% 14.0% 3.6% -1.1% 37.4% · ·
Revenue CAGR 3Y 3-point trend, +120.6% 26.7% 5.3% 12.1% · · · ·
Revenue CAGR 5Y 22.5% · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for RNA
Metric Trend 2025202420232022202120202019
Revenue TTM 6-point trend, +176.3% $19M $11M $10M $9M $9M $7M ·
Net Income TTM 6-point trend, -1443.5% $-685M $-322M $-212M $-174M $-118M $-44M ·
Market Cap 6-point trend, +1037.6% $10.91B $3.49B $717M $1.55B $1.14B $959M ·
P/E 6-point trend, -16.6% -14.5 -10.1 -3.1 -6.6 -8.3 -12.4 ·
P/S 6-point trend, +311.7% 581.5 319.9 75.0 167.8 121.7 141.3 ·
P/B 6-point trend, +106.3% 6.5 2.4 1.4 2.7 3.0 3.1 ·
P / Tangible Book 6-point trend, +106.3% 6.5 2.4 1.4 2.7 3.0 3.1 ·
P / Cash Flow 6-point trend, +35.1% -16.8 -11.6 -6.0 -11.4 -12.0 -25.8 ·
P / FCF 6-point trend, +34.5% -16.4 -11.3 -5.8 -11.1 -11.5 -25.1 ·
Earnings Yield 6-point trend, +14.2% -6.9% -9.9% -32.1% -15.0% -12.0% -8.0% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $19M$11M$10M$9M$9M
Operating Margin % -3977.3%-3477.4%-2464.4%-1939.6%-1265.8%
Net Income $-685M$-322M$-212M$-174M$-118M
Diluted EPS $-4.97$-2.89$-2.91$-3.34$-2.85
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 9.215.77.612.013.9
Quick Ratio 2.02.22.36.613.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-664M$-308M$-123M$-139M$-99M

Latest News Recent headlines mentioning this company

My Metrics Your personal watchlist — selected rows from Full Fundamentals

📊

Pick the metrics that matter to you — click the ➕ next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.

Institutional owners (13F) 20 filers · $102.7M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
0 (0 vs prior Q) 1 (-322 vs prior Q) 0 (0 vs prior Q) 1 (0 vs prior Q) -8K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
KRYGER CAPITAL Ltd $75,398,932 1,045,320 73.42% Shares
VANGUARD GROUP INC $6,863,530 95,155 6.68% Shares
EFG Asset Management (North America) Corp. $6,499,913 149,149 6.33% Shares
AXA Investment Managers S.A. $4,429,239 101,658 4.31% Shares
ANGELO GORDON & CO., L.P. $3,245,850 45,000 3.16% Shares
Toroso Investments, LLC $2,628,417 36,440 2.56% Shares
WOLVERINE TRADING, LLC $1,023,120 24,000 1.00% Call option
Orion Portfolio Solutions, LLC $675,595 22,886 0.66% Shares
CIBC WORLD MARKETS CORP $552,372 7,658 0.54% Shares
WOLVERINE TRADING, LLC $456,141 10,700 0.44% Put option
Eisler Capital Management Ltd. $322,088 7,600 0.31% Call option
WOLVERINE TRADING, LLC $285,493 6,697 0.28% Shares
Nuveen Asset Management, LLC $167,268 5,752 0.16% Shares
AlphaQuest LLC $104,589 1,450 0.10% Shares
OLIVER LAGORE VANVALIN INVESTMENT GROUP $19,572 663 0.02% Shares
Lindbrook Capital, LLC $16,708 566 0.02% Shares
COMERICA BANK $10,956 152 0.01% Shares
Byrne Asset Management LLC $1,372 102 0.00% Shares
FTB Advisors, Inc. $511 18 0.00% Shares
Hemington Wealth Management $0 7 0.00% Shares

Company insiders 20 insiders · 11 officers · 9 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Sarah Boyce President and CEO Feb. 27, 2026 D 0 0 0 $0
Michael F Maclean Chief Financial Officer Feb. 27, 2026 D 0 0 0 $0
Joseph Baroldi Chief Operating Officer Feb. 2, 2021 A 0 0 $0
Charles Calderaro III Chief Technical Officer Feb. 27, 2026 D 0 0 0 $0
Kathleen P. Gallagher Chief Program Officer Feb. 27, 2026 D 0 0 0 $0
Teresa Mccarthy Chief Human Resources Officer Feb. 27, 2026 D 0 0 0 $0
Michael W. Flanagan Chief Scientific Officer Feb. 27, 2026 D 0 0 0 $0
Steven George Hughes Chief Medical Officer Feb. 27, 2026 D 0 0 0 $0
Eric Mosbrooker Chief Commercial Officer Feb. 27, 2026 D 0 0 0 $0
John B Moriarty Chief Legal Officer Feb. 27, 2026 D 0 0 0 $0
Jae B. Kim Chief Medical Officer Feb. 2, 2021 A 0 0 $0
Simona Skerjanec Director Feb. 27, 2026 D 0 0 0 $0
Jean Jinsun Kim Director Feb. 27, 2026 D 0 0 0 $0
Tamar Thompson Director Feb. 27, 2026 D 0 0 0 $0
Noreen Henig Director Feb. 27, 2026 D 0 0 0 $0
Troy Edward Wilson Director Feb. 27, 2026 D 0 0 0 $0
Edward M. Kaye MD Director Feb. 27, 2026 D 0 0 0 $0
Carsten Boess Director Feb. 27, 2026 D 0 0 0 $0
LEVIN ARTHUR A Director Feb. 27, 2026 D 0 0 0 $0
Roderick Wong, M.D. June 16, 2021 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
RTW Investments, LP, Roderick Wong ×6 filings Oct. 29, 2025 3.10% Amendment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 15 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWC · iShares Trust 0.04% 48,184 SH Aug. 8, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… 0.02% 4,415 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 82,327 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 10,724 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.01% 85,960 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.01% 369,738 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.00% 40,687 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.00% 2,952 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 3,267 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 188,626 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 518,416 SH Aug. 8, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.00% 8,760 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 3,882 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 933 SH Aug. 8, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.00% 3,329 SH Aug. 8, 2026 Daily