TNYA Tenaya Therapeutics, Inc. - Common Stock
TNYA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
TNYA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
10-Year Performance Revenue, net income, margins and EPS trends
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Financial Health Debt, liquidity, solvency — balance sheet strength
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
TNYA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
- Strong Buy 4 30.8%
- Buy 8 61.5%
- Hold 1 7.7%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
5 analysts · 2026-08-17Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-0.20 | $-0.07 | -0.13% |
| March 31, 2026 | $-0.09 | $-0.09 | -0.00% |
| Dec. 31, 2025 | $-0.12 | $-0.12 | 0.00% |
| Sept. 30, 2025 | $-0.12 | $-0.15 | 0.03% |
| June 30, 2025 | $-0.14 | $-0.26 | 0.12% |
| March 31, 2025 | $-0.24 | $-0.19 | -0.05% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| TNYA | $154M | -1.2 | — | — | -81.2% | — |
| NKTX | $131M | -1.3 | — | — | -31.1% | — |
| OKUR | — | -0.7 | — | -1733.7% | -88.6% | — |
| CRBU | $151M | -1.0 | 11.7% | -1327.4% | -102.8% | — |
| CNTB | $159M | -2.8 | -99.8% | -86687.5% | -97.9% | — |
| CNTN | $112M | -2.7 | — | — | -18.0% | — |
| HUMA | — | — | — | — | — | — |
| UNCY | $128M | -3.5 | -29.0% | — | -113.9% | — |
| EQ | $95M | -4.0 | 13.9% | — | -133.1% | — |
| HURA | — | -1.2 | — | — | — | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $69M | $87M | $98M | $95M | $54M | $31M | |
| SG&A Expense | $25M | $29M | $33M | $31M | $18M | $8M | |
| Operating Expenses | $93M | $116M | $131M | $126M | $73M | $39M | |
| Operating Income | $-93M | $-116M | $-131M | $-126M | $-73M | $-39M | |
| Interest Income | $3M | $5M | $7M | $2M | $108.0K | $87.0K | |
| Other Non-op | $52.0K | $82.0K | $53.0K | $2.0K | $-23.0K | $355.0K | |
| Pretax Income | $-91M | $-111M | $-124M | $-124M | $-73M | $-38M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-91M | $-111M | $-124M | $-124M | $-73M | $-38M | |
| EPS (Basic) | $-0.59 | $-1.31 | $-1.68 | $-2.76 | $-4.10 | · | |
| EPS (Diluted) | $-0.59 | $-1.31 | $-1.68 | $-2.76 | $-4.10 | · | |
| Shares (Basic) | 152,971,259 | 84,822,468 | 73,786,126 | 44,823,597 | 17,734,166 | · | |
| Shares (Diluted) | 152,971,259 | 84,822,468 | 73,786,126 | 44,823,597 | 17,734,166 | · | |
| EBITDA | $-85M | $-107M | $-123M | $-119M | $-70M | · |
Balance Sheet 23
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $101M | $4M | $46M | $95M | $38M | $129M | |
| Short-term Investments | · | $57M | $59M | $91M | $213M | · | |
| Prepaid Expense | $5M | $6M | $7M | $7M | $4M | $1M | |
| Other Current Assets | $1M | $842.0K | $1M | $938.0K | · | · | |
| Current Assets | $106M | $67M | $112M | $194M | $255M | $130M | |
| PP&E (Net) | $28M | $36M | $43M | $51M | $43M | $17M | |
| PP&E (Gross) | $68M | $68M | $68M | $67M | $52M | $24M | |
| Accum. Depreciation | $40M | $32M | $24M | $16M | $9M | $7M | |
| Other Non-current Assets | $4M | $5M | $6M | $5M | $4M | $465.0K | |
| Total Assets | $147M | $120M | $171M | $279M | $314M | $148M | |
| Accounts Payable | $4M | $5M | $6M | $10M | $11M | $1M | |
| Accrued Liabilities | $9M | $8M | $13M | $11M | $9M | $3M | |
| Current Liabilities | $15M | $16M | $23M | $24M | $22M | $5M | |
| Capital Leases | $8M | $11M | $8M | $11M | $14M | · | |
| Other Non-current Liabilities | $410.0K | $281.0K | $253.0K | $228.0K | $182.0K | $19.0K | |
| Total Liabilities | $24M | $27M | $31M | $36M | $36M | $9M | |
| Common Stock | $21.0K | $8.0K | $7.0K | $7.0K | $4.0K | · | |
| Paid-in Capital | $728M | $607M | $543M | $523M | $434M | $2M | |
| Retained Earnings | $-605M | $-514M | $-403M | $-279M | $-156M | $-83M | |
| AOCI | $0 | $28.0K | $-106.0K | $-378.0K | $-141.0K | · | |
| Stockholders' Equity | $123M | $93M | $139M | $243M | $279M | $-81M | |
| Liabilities + Equity | $147M | $120M | $171M | $279M | $314M | $148M | |
| Shares Outstanding | 216,760,283 | 86,542,340 | 68,330,342 | 66,857,113 | 41,291,374 | 1,210,306 |
Cash Flow 13
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $8M | $8M | $9M | $6M | $3M | $2M | |
| Stock-based Comp | $13M | $17M | $15M | $11M | $3M | $741.0K | |
| Other Non-cash | $851.0K | $-4M | $-2M | $1M | $6M | · | |
| Operating Cash Flow | $-68M | $-91M | $-102M | $-104M | $-61M | $-35M | |
| CapEx | $618.0K | $1M | $1M | $21M | $25M | $10M | |
| Investing Cash Flow | $56M | $1M | $49M | $84M | $-239M | $-7M | |
| Stock Issued | · | · | $4M | · | · | · | |
| Stock Repurchased | · | · | · | · | $13.0K | $1.0K | |
| Net Stock Activity | · | · | $4M | · | $-13.0K | · | |
| Financing Cash Flow | $108M | $48M | $4M | $78M | $209M | $147M | |
| Net Change in Cash | $96M | $-42M | $-49M | $57M | $-90M | $105M | |
| Taxes Paid | $0 | · | · | · | · | · | |
| Free Cash Flow | $-69M | $-92M | $-103M | $-125M | $-86M | · |
Profitability 3
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -67.9% | -76.5% | -55.2% | -41.7% | -31.5% | · | |
| ROE | -81.2% | -108.2% | -81.5% | -56.2% | -25.0% | · | |
| ROIC | -75.7% | -124.9% | -94.1% | -51.6% | -26.1% | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 6.8 | 4.2 | 4.9 | 8.0 | 11.7 | · | |
| Quick Ratio | 6.5 | 3.8 | 4.6 | 7.7 | 11.5 | · |
Valuation (TTM) 8
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-91M | $-111M | $-124M | $-124M | $-73M | · | |
| Market Cap | $154M | $124M | $221M | $134M | $782M | · | |
| P/E | -1.2 | -1.1 | -1.9 | -0.7 | -4.6 | · | |
| P/B | 1.3 | 1.3 | 1.6 | 0.6 | 2.8 | · | |
| P / Tangible Book | 1.3 | 1.3 | 1.6 | 0.6 | 2.8 | · | |
| P / Cash Flow | -2.3 | -1.4 | -2.2 | -1.3 | -12.9 | · | |
| P / FCF | -2.2 | -1.4 | -2.1 | -1.1 | -9.1 | · | |
| Earnings Yield | -82.9% | -91.6% | -51.8% | -137.3% | -21.6% | · |
Income Statement 15
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Revenue | $1M | $225.0K | · | · | $0 | $0 | |
| R&D Expense | $17M | $15M | $15M | $15M | $17M | $21M | |
| SG&A Expense | $5M | $5M | $6M | $6M | $7M | $6M | |
| Operating Expenses | $45M | $20M | $21M | $21M | $24M | $28M | |
| Operating Income | $-44M | $-20M | $-21M | $-21M | $-24M | $-28M | |
| Interest Income | $697.0K | $793.0K | $574.0K | $658.0K | $815.0K | $635.0K | |
| Other Non-op | $-2.0K | · | $26.0K | $3.0K | $-16.0K | $39.0K | |
| Pretax Income | $-43M | $-19M | $-20M | $-20M | $-23M | $-27M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-43M | $-19M | $-20M | $-20M | $-23M | $-27M | |
| EPS (Basic) | $-0.20 | $-0.09 | $-0.09 | $-0.12 | $-0.14 | $-0.24 | |
| EPS (Diluted) | $-0.20 | $-0.09 | $-0.09 | $-0.12 | $-0.14 | $-0.24 | |
| Shares (Basic) | 217,574,637 | 216,883,164 | -283,035,570 | 163,345,972 | 162,791,579 | 109,869,278 | |
| Shares (Diluted) | 217,574,637 | 216,883,164 | -283,035,570 | 163,345,972 | 162,791,579 | 109,869,278 | |
| EBITDA | $-44M | $-18M | · | $-21M | $-24M | $-25M |
Balance Sheet 24
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $78M | $81M | $101M | $56M | $63M | $54M | |
| Short-term Investments | · | · | · | · | $9M | $34M | |
| Receivables | $371.0K | $11M | · | · | · | · | |
| Prepaid Expense | $8M | $5M | $5M | $5M | $4M | $6M | |
| Other Current Assets | $4M | $25.0K | $1M | $990.0K | $218.0K | $1M | |
| Current Assets | $86M | $97M | $106M | $61M | $76M | $94M | |
| PP&E (Net) | $2M | $26M | $28M | $29M | $31M | $33M | |
| PP&E (Gross) | $27M | $68M | $68M | $68M | $68M | $68M | |
| Accum. Depreciation | $25M | $42M | $40M | $39M | $37M | $35M | |
| Other Non-current Assets | $2M | $4M | $4M | $4M | $4M | $5M | |
| Total Assets | $94M | $135M | $147M | $105M | $122M | $144M | |
| Accounts Payable | $3M | $2M | $4M | $3M | $3M | $5M | |
| Accrued Liabilities | $8M | $6M | $9M | $7M | $7M | $6M | |
| Current Liabilities | $19M | $17M | $15M | $13M | $13M | $14M | |
| Capital Leases | $1M | $7M | $8M | $9M | $9M | $10M | |
| Other Non-current Liabilities | $103.0K | $418.0K | $410.0K | $301.0K | $293.0K | $287.0K | |
| Total Liabilities | $24M | $29M | $24M | $22M | $22M | $25M | |
| Common Stock | $22.0K | $21.0K | $21.0K | $16.0K | $16.0K | $16.0K | |
| Paid-in Capital | $737M | $730M | $728M | $668M | $664M | $661M | |
| Retained Earnings | $-668M | $-624M | $-605M | $-585M | $-565M | $-541M | |
| AOCI | · | · | $0 | · | $-1.0K | $-10.0K | |
| Stockholders' Equity | $69M | $106M | $123M | $83M | $100M | $119M | |
| Liabilities + Equity | $94M | $135M | $147M | $105M | $122M | $144M | |
| Shares Outstanding | 224,230,012 | 216,998,876 | 216,760,283 | · | · | · |
Cash Flow 9
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $2M | $3M | |
| Stock-based Comp | $2M | $2M | $3M | $3M | $4M | $4M | |
| Other Non-cash | · | $-4M | · | · | · | $-3M | |
| Operating Cash Flow | $-4M | $-19M | $-14M | $-16M | $-16M | $-23M | |
| CapEx | $159.0K | $11.0K | $67.0K | $26.0K | $142.0K | $383.0K | |
| Investing Cash Flow | $-159.0K | $-11.0K | $-67.0K | $9M | $25M | $22M | |
| Financing Cash Flow | $909.0K | $-415.0K | $58M | $380.0K | $-476.0K | $50M | |
| Net Change in Cash | $-3M | $-20M | $44M | $-6M | $9M | $49M | |
| Free Cash Flow | · | $-19M | · | · | · | $-23M |
Profitability 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Operating Margin | -3971.9% | -8917.8% | · | · | · | · | |
| Net Margin | -3909.3% | -8565.3% | · | · | · | · | |
| Pretax Margin | -3909.3% | -8565.3% | · | · | · | · | |
| EBITDA Margin | -3971.9% | -8134.2% | · | · | · | · | |
| ROA | -40.2% | -13.8% | · | -16.5% | -16.3% | -16.3% | |
| ROE | -51.3% | -17.1% | · | -20.7% | -19.9% | -19.4% | |
| ROIC | -63.5% | -18.9% | · | · | · | -23.1% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 4.5 | 5.8 | · | 4.6 | 6.0 | 6.7 | |
| Quick Ratio | 4.1 | 5.5 | · | 4.3 | 5.7 | 6.2 |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | · | · | · | |
| Receivables Turnover | 6.0 | 0.0 | · | · | · | · |
Valuation (TTM) 8
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-106M | $-90M | · | $-96M | $-105M | $-114M | |
| Market Cap | $166M | $150M | · | · | · | · | |
| P/E | -1.3 | -1.2 | · | -2.0 | -0.6 | -0.4 | |
| P/B | 2.4 | 1.4 | · | · | · | · | |
| P / Tangible Book | 2.4 | 1.4 | · | · | · | · | |
| P / Cash Flow | · | -7.8 | · | · | · | · | |
| P / FCF | · | -7.8 | · | · | · | · | |
| Earnings Yield | -74.4% | -85.3% | · | -49.4% | -166.9% | -224.6% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Net Income | $-91M | $-111M | $-124M | $-124M | $-73M |
| Diluted EPS | $-0.59 | $-1.31 | $-1.68 | $-2.76 | $-4.10 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 6.8 | 4.2 | 4.9 | 8.0 | 11.7 |
| Quick Ratio | 6.5 | 3.8 | 4.6 | 7.7 | 11.5 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-69M | $-92M | $-103M | $-125M | $-86M |
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Institutional owners (13F) 116 filers · $32.3M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 24 (0 vs prior Q) | 19 (+3 vs prior Q) | 32 (0 vs prior Q) | 17 (-3 vs prior Q) | +7.0M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD CAPITAL MANAGEMENT LLC | $5,247,833 | 7,101,263 | 16.27% | Shares |
| MILLENNIUM MANAGEMENT LLC | $4,752,153 | 6,429,648 | 14.73% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $3,164,161 | 4,281,100 | 9.81% | Shares |
| CITADEL ADVISORS LLC | $3,104,220 | 4,200,000 | 9.62% | Shares |
| Empery Asset Management, LP | $2,855,228 | 3,863,115 | 8.85% | Shares |
| Burkehill Global Management, LP | $1,478,200 | 2,000,000 | 4.58% | Shares |
| ADAR1 Capital Management, LLC | $1,149,670 | 1,555,500 | 3.56% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $1,086,935 | 1,469,540 | 3.37% | Shares |
| Raiffeisen Bank International AG | $881,880 | 1,200,000 | 2.73% | Shares |
| Euclidean Capital LLC | $750,708 | 1,015,705 | 2.33% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $729,766 | 987,505 | 2.26% | Shares |
| Mirador Capital Partners LP | $668,957 | 905,097 | 2.07% | Shares |
| STATE STREET CORP | $523,816 | 708,721 | 1.62% | Shares |
| VANGUARD GROUP INC | $495,619 | 696,094 | 1.54% | Shares |
| Squarepoint Ops LLC | $487,249 | 659,247 | 1.51% | Shares |
| StepStone Group LP | $318,892 | 462,163 | 0.99% | Shares |
| JANE STREET GROUP, LLC | $290,043 | 392,427 | 0.90% | Shares |
| TWO SIGMA INVESTMENTS, LP | $281,442 | 380,790 | 0.87% | Shares |
| TWO SIGMA ADVISERS, LP | $280,687 | 394,500 | 0.87% | Shares |
| Casdin Capital, LLC | $267,531 | 361,969 | 0.83% | Shares |
| Invesco Ltd. | $262,279 | 354,862 | 0.81% | Shares |
| NORTHERN TRUST CORP | $256,003 | 346,371 | 0.79% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $240,441 | 325,316 | 0.75% | Shares |
| XTX Topco Ltd | $231,699 | 313,488 | 0.72% | Shares |
| DAFNA Capital Management LLC | $221,730 | 300,000 | 0.69% | Shares |
| UBS Group AG | $188,116 | 254,555 | 0.58% | Shares |
| Marex Group Ltd | $174,058 | 235,500 | 0.54% | Shares |
| CITADEL ADVISORS LLC | $148,485 | 200,900 | 0.46% | Call option |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $143,977 | 194,800 | 0.45% | Shares |
| Almanack Investment Partners, LLC. | $124,317 | 168,200 | 0.39% | Shares |
| MARSHALL WACE, LLP | $107,212 | 144,881 | 0.33% | Shares |
| Nuveen Asset Management, LLC | $99,674 | 69,702 | 0.31% | Shares |
| CITIGROUP INC | $68,305 | 92,417 | 0.21% | Shares |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $66,310 | 76,183 | 0.21% | Shares |
| GOLDMAN SACHS GROUP INC | $66,149 | 89,500 | 0.21% | Shares |
| Pathstone Holdings, LLC | $55,433 | 75,000 | 0.17% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $54,020 | 73,000 | 0.17% | Call option |
| Cetera Investment Advisers | $42,221 | 57,125 | 0.13% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $41,670 | 56,379 | 0.13% | Shares |
| Vanguard Global Advisers, LLC | $37,002 | 50,070 | 0.11% | Shares |
| Callan Family Office, LLC | $37,000 | 50,061 | 0.11% | Shares |
| Integrated Wealth Concepts LLC | $35,388 | 47,880 | 0.11% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $32,782 | 44,300 | 0.10% | Put option |
| JANE STREET GROUP, LLC | $31,633 | 42,800 | 0.10% | Call option |
| Point72 Asia (Singapore) Pte. Ltd. | $28,447 | 17,560 | 0.09% | Shares |
| Spark Investment Management LLC | $26,238 | 35,500 | 0.08% | Shares |
| Vanguard Personalized Indexing Management, LLC | $25,773 | 34,871 | 0.08% | Shares |
| OSAIC HOLDINGS, INC. | $25,576 | 34,563 | 0.08% | Shares |
| China Universal Asset Management Co., Ltd. | $25,525 | 34,535 | 0.08% | Shares |
| H D Vest Advisory Services | $23,531 | 38,500 | 0.07% | Shares |
| R Squared Ltd | $23,284 | 31,503 | 0.07% | Shares |
| Integrity Wealth Solutions LLC | $23,244 | 31,449 | 0.07% | Shares |
| EWA, LLC | $21,180 | 28,656 | 0.07% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $18,030 | 24,395 | 0.06% | Shares |
| ROYAL BANK OF CANADA | $18,000 | 24,115 | 0.06% | Shares |
| Bank of New York Mellon Corp | $17,742 | 24,005 | 0.06% | Shares |
| Mariner, LLC | $16,260 | 22,000 | 0.05% | Shares |
| Quantinno Capital Management LP | $15,870 | 21,472 | 0.05% | Shares |
| HighPoint Advisor Group LLC | $15,743 | 21,300 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $15,447 | 20,900 | 0.05% | Put option |
| BANK OF AMERICA CORP /DE/ | $15,311 | 20,719 | 0.05% | Shares |
| VSM Wealth Advisory, LLC | $14,782 | 20,000 | 0.05% | Shares |
| Parkwoods Wealth Partners, LLC | $13,673 | 18,500 | 0.04% | Shares |
| CITIZENS FINANCIAL GROUP INC/RI | $13,304 | 18,000 | 0.04% | Shares |
| World Investment Advisors | $13,009 | 18,787 | 0.04% | Shares |
| Federation des caisses Desjardins du Quebec | $12,933 | 17,500 | 0.04% | Shares |
| LPL Financial LLC | $12,530 | 16,953 | 0.04% | Shares |
| Peregrine Asset Advisers, Inc. | $12,007 | 16,245 | 0.04% | Shares |
| Private Advisor Group, LLC | $11,899 | 16,100 | 0.04% | Shares |
| SIMPLEX TRADING, LLC | $11,849 | 16,035 | 0.04% | Shares |
| Qube Research & Technologies Ltd | $11,398 | 15,422 | 0.04% | Shares |
| COMMERCE BANK | $11,086 | 15,000 | 0.03% | Shares |
| Northern Lights Advisors, Inc. | $11,052 | 14,953 | 0.03% | Shares |
| Spectrum Investment Advisors, Inc. | $10,383 | 14,048 | 0.03% | Shares |
| RIK SAYLOR FINANCIAL, INC. | $9,978 | 13,500 | 0.03% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $9,948 | 13,459 | 0.03% | Shares |
| BARCLAYS PLC | $9,715 | 13,145 | 0.03% | Shares |
| Avior Wealth Management, LLC | $9,682 | 13,100 | 0.03% | Shares |
| Aptus Capital Advisors, LLC | $8,917 | 12,065 | 0.03% | Shares |
| ENDEAVOR PRIVATE WEALTH, INC. | $8,426 | 11,400 | 0.03% | Shares |
| Point72 Asset Management, L.P. | $8,386 | 11,346 | 0.03% | Shares |
| MML INVESTORS SERVICES, LLC | $8,353 | 11,302 | 0.03% | Shares |
| Galvin, Gaustad & Stein, LLC | $8,130 | 11,000 | 0.03% | Shares |
| Sequoia Financial Advisors, LLC | $7,927 | 10,725 | 0.02% | Shares |
| EP Wealth Advisors, LLC | $7,576 | 10,250 | 0.02% | Shares |
| PFG Investments, LLC | $7,465 | 10,100 | 0.02% | Shares |
| Quadcap Wealth Management, LLC | $7,391 | 10,000 | 0.02% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $7,173 | 9,705 | 0.02% | Shares |
| Cubist Systematic Strategies, LLC | $6,666 | 4,115 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $6,154 | 8,327 | 0.02% | Shares |
| IFP Advisors, Inc | $4,418 | 5,978 | 0.01% | Shares |
| Ameritas Advisory Services, LLC | $3,696 | 5,000 | 0.01% | Shares |
| JPMORGAN CHASE & CO | $2,265 | 3,082 | 0.01% | Shares |
| GSA CAPITAL PARTNERS LLP | $1,973 | 2,669,033 | 0.01% | Shares |
| TFC Financial Management, Inc. | $1,848 | 2,500 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $1,774 | 2,400 | 0.01% | Shares |
| FMR LLC | $1,706 | 2,308 | 0.01% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $1,664 | 2,252 | 0.01% | Shares |
| WELLS FARGO & COMPANY/MN | $1,478 | 2,000 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $1,170 | 1,583 | 0.00% | Shares |
Company insiders 18 insiders · 5 officers · 11 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Eric J Hyllengren | Chief Financial Officer | July 13, 2026 A | — | 0 | 0 | $0 |
| Tomohiro Higa | SVP, Finance | May 18, 2026 S | 118,267 | 0 | 5 | $-5,211 |
| Chihiro Saito | SVP, Accounting and Fin. Ops. | Nov. 18, 2024 S | 60,983 | 0 | 0 | $0 |
| Timothy Hoey | Chief Scientific Officer | March 5, 2024 S | 245,346 | 0 | 0 | $0 |
| Leone D Patterson | Chief Fin. and Bus. Officer | Feb. 23, 2024 A | 95,755 | 0 | 0 | $0 |
| Amy L. Burroughs | Director | May 28, 2026 A | — | 0 | 0 | $0 |
| Deepak Srivastava | Director | May 28, 2026 A | 372,435 | 0 | 0 | $0 |
| Catherine Stehman-Breen | Director | May 28, 2026 A | — | 0 | 0 | $0 |
| June Lee | Director | May 28, 2026 A | — | 0 | 0 | $0 |
| Karah Herdman Parschauer | Director | May 28, 2026 A | — | 0 | 0 | $0 |
| Jeffrey T. Walsh | Director | May 28, 2026 A | — | 0 | 0 | $0 |
| Sanders R Williams | Director | May 28, 2026 A | — | 0 | 0 | $0 |
| David V Goeddel | Director | May 29, 2025 A | 49,313,559 | 0 | 0 | $0 |
| Jin-Long Chen | Director | June 9, 2023 A | — | 0 | 0 | $0 |
| Eli Casdin | Director | June 10, 2022 A | 361,969 | 0 | 0 | $0 |
| Jeenjoo Kang | Director | Aug. 3, 2021 C | 25,000 | 0 | 0 | $0 |
| Whittemore Tingley | — | Aug. 17, 2026 S | 214,073 | 0 | 9 | $-14,865 |
| Faraz Ali | — | Aug. 17, 2026 S | 417,782 | 0 | 9 | $-32,132 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| The Column Group III, LP, The Column Group III-A, LP, The Column Group III GP, LP, The Column Group Opportunity III, LP, The Column Group Opportunity III GP, LP, TCG Opportunity III GP, LLC, Tim Kutzkey, Peter Svennilson ×8 filings | Feb. 26, 2026 | 23.10% | Amendment | — | SEC |
| Casdin Capital, LLC, Casdin Partners Master Fund, L.P., Casdin Partners GP, LLC, Eli Casdin ×4 filings | March 7, 2025 | 4.30% | Amendment | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 7 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| QQQS · Invesco Exchange-Traded Fund Trust … | 0.41% | 128,678 SH | Aug. 8, 2026 | Daily |
| IBB · iShares Trust | 0.01% | 1,540,476 SH | Aug. 8, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.01% | 11,686 SH | Aug. 8, 2026 | Daily |
| BIB · ProShares Trust | 0.01% | 8,012 NS | May 31, 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.01% | 221,764 SH | Aug. 8, 2026 | Daily |
| VXF · VANGUARD INDEX FUNDS | 0.00% | 1,768,551 SH | Aug. 8, 2026 | Daily |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 5,136,220 SH | Aug. 8, 2026 | Daily |