TNYA Tenaya Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$0.72
Price · Aug 19, 2026
Fundamentals as of Aug 5, 2026

TNYA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.72
Market Cap
$156M
P/E (TTM)
-1.2
EPS (TTM)
$-0.59
Revenue (TTM)
Div Yield
ROE
-81.2%
Debt/Equity
52W Range
$1 – $2

TNYA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS $-0.59
5-point trend, +85.6%
2021-12-31 2025-12-31
Free Cash Flow $-69M
5-point trend, +19.8%
2021-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
TNYA
Peer Median
P/E (TTM)
5-point trend, +73.9%
-1.2
1.2
P/B
5-point trend, -55.4%
1.3
1.2
Price / FCF
5-point trend, +75.4%
-2.3

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
TNYA
Peer Median
ROA
5-point trend, -115.8%
-67.9%
-58.9%
ROE
5-point trend, -225.1%
-81.2%
-79.0%
ROIC
5-point trend, -189.7%
-75.7%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
TNYA
Peer Median
Current Ratio
5-point trend, -41.7%
6.8
5.4
Quick Ratio
5-point trend, -43.6%
6.5

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
TNYA
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
TNYA
Peer Median
EPS (Diluted)
5-point trend, +85.6%
$-0.59

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
TNYA
Peer Median

TNYA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 13 analysts
  • Strong Buy 4 30.8%
  • Buy 8 61.5%
  • Hold 1 7.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

5 analysts · 2026-08-17
Median target $3.00 +317.0%
Mean target $3.20 +344.8%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.00%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.20 $-0.07 -0.13%
March 31, 2026 $-0.09 $-0.09 -0.00%
Dec. 31, 2025 $-0.12 $-0.12 0.00%
Sept. 30, 2025 $-0.12 $-0.15 0.03%
June 30, 2025 $-0.14 $-0.26 0.12%
March 31, 2025 $-0.24 $-0.19 -0.05%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
TNYA $154M -1.2 -81.2%
NKTX $131M -1.3 -31.1%
OKUR -0.7 -1733.7% -88.6%
CRBU $151M -1.0 11.7% -1327.4% -102.8%
CNTB $159M -2.8 -99.8% -86687.5% -97.9%
CNTN $112M -2.7 -18.0%
HUMA
UNCY $128M -3.5 -29.0% -113.9%
EQ $95M -4.0 13.9% -133.1%
HURA -1.2

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for TNYA
Metric Trend 202520242023202220212020
R&D Expense 6-point trend, +120.6% $69M $87M $98M $95M $54M $31M
SG&A Expense 6-point trend, +216.4% $25M $29M $33M $31M $18M $8M
Operating Expenses 6-point trend, +139.9% $93M $116M $131M $126M $73M $39M
Operating Income 6-point trend, -139.9% $-93M $-116M $-131M $-126M $-73M $-39M
Interest Income 6-point trend, +2982.8% $3M $5M $7M $2M $108.0K $87.0K
Other Non-op 6-point trend, -85.4% $52.0K $82.0K $53.0K $2.0K $-23.0K $355.0K
Pretax Income 6-point trend, -136.0% $-91M $-111M $-124M $-124M $-73M $-38M
Income Tax Flat — no change across 6 periods $0 $0 $0 $0 $0 $0
Net Income 6-point trend, -136.0% $-91M $-111M $-124M $-124M $-73M $-38M
EPS (Basic) 5-point trend, +85.6% $-0.59 $-1.31 $-1.68 $-2.76 $-4.10 ·
EPS (Diluted) 5-point trend, +85.6% $-0.59 $-1.31 $-1.68 $-2.76 $-4.10 ·
Shares (Basic) 5-point trend, +762.6% 152,971,259 84,822,468 73,786,126 44,823,597 17,734,166 ·
Shares (Diluted) 5-point trend, +762.6% 152,971,259 84,822,468 73,786,126 44,823,597 17,734,166 ·
EBITDA 5-point trend, -21.5% $-85M $-107M $-123M $-119M $-70M ·
Balance Sheet 23
Annual Balance Sheet data for TNYA
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, -21.8% $101M $4M $46M $95M $38M $129M
Short-term Investments 4-point trend, -73.2% · $57M $59M $91M $213M ·
Prepaid Expense 6-point trend, +252.6% $5M $6M $7M $7M $4M $1M
Other Current Assets 4-point trend, +9.3% $1M $842.0K $1M $938.0K · ·
Current Assets 6-point trend, -18.8% $106M $67M $112M $194M $255M $130M
PP&E (Net) 6-point trend, +61.0% $28M $36M $43M $51M $43M $17M
PP&E (Gross) 6-point trend, +183.0% $68M $68M $68M $67M $52M $24M
Accum. Depreciation 6-point trend, +495.7% $40M $32M $24M $16M $9M $7M
Other Non-current Assets 6-point trend, +813.1% $4M $5M $6M $5M $4M $465.0K
Total Assets 6-point trend, -0.8% $147M $120M $171M $279M $314M $148M
Accounts Payable 6-point trend, +252.1% $4M $5M $6M $10M $11M $1M
Accrued Liabilities 6-point trend, +179.5% $9M $8M $13M $11M $9M $3M
Current Liabilities 6-point trend, +206.2% $15M $16M $23M $24M $22M $5M
Capital Leases 5-point trend, -43.0% $8M $11M $8M $11M $14M ·
Other Non-current Liabilities 6-point trend, +2057.9% $410.0K $281.0K $253.0K $228.0K $182.0K $19.0K
Total Liabilities 6-point trend, +171.2% $24M $27M $31M $36M $36M $9M
Common Stock 5-point trend, +425.0% $21.0K $8.0K $7.0K $7.0K $4.0K ·
Paid-in Capital 6-point trend, +45875.5% $728M $607M $543M $523M $434M $2M
Retained Earnings 6-point trend, -630.6% $-605M $-514M $-403M $-279M $-156M $-83M
AOCI 5-point trend, +100.0% $0 $28.0K $-106.0K $-378.0K $-141.0K ·
Stockholders' Equity 6-point trend, +251.6% $123M $93M $139M $243M $279M $-81M
Liabilities + Equity 6-point trend, -0.8% $147M $120M $171M $279M $314M $148M
Shares Outstanding 6-point trend, +17809.5% 216,760,283 86,542,340 68,330,342 66,857,113 41,291,374 1,210,306
Cash Flow 13
Annual Cash Flow data for TNYA
Metric Trend 202520242023202220212020
D&A 6-point trend, +239.8% $8M $8M $9M $6M $3M $2M
Stock-based Comp 6-point trend, +1660.6% $13M $17M $15M $11M $3M $741.0K
Other Non-cash 5-point trend, -85.8% $851.0K $-4M $-2M $1M $6M ·
Operating Cash Flow 6-point trend, -92.6% $-68M $-91M $-102M $-104M $-61M $-35M
CapEx 6-point trend, -93.7% $618.0K $1M $1M $21M $25M $10M
Investing Cash Flow 6-point trend, +900.0% $56M $1M $49M $84M $-239M $-7M
Stock Issued · · $4M · · ·
Stock Repurchased 2-point trend, +1200.0% · · · · $13.0K $1.0K
Net Stock Activity 2-point trend, +29853.8% · · $4M · $-13.0K ·
Financing Cash Flow 6-point trend, -26.4% $108M $48M $4M $78M $209M $147M
Net Change in Cash 6-point trend, -8.2% $96M $-42M $-49M $57M $-90M $105M
Taxes Paid $0 · · · · ·
Free Cash Flow 5-point trend, +19.8% $-69M $-92M $-103M $-125M $-86M ·
Profitability 3
Annual Profitability data for TNYA
Metric Trend 202520242023202220212020
ROA 5-point trend, -115.8% -67.9% -76.5% -55.2% -41.7% -31.5% ·
ROE 5-point trend, -225.1% -81.2% -108.2% -81.5% -56.2% -25.0% ·
ROIC 5-point trend, -189.7% -75.7% -124.9% -94.1% -51.6% -26.1% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for TNYA
Metric Trend 202520242023202220212020
Current Ratio 5-point trend, -41.7% 6.8 4.2 4.9 8.0 11.7 ·
Quick Ratio 5-point trend, -43.6% 6.5 3.8 4.6 7.7 11.5 ·
Per Share 4
Annual Per Share data for TNYA
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, -91.6% $0.57 $1.07 $2.04 $3.64 $6.75 ·
Cash Flow / Share 4-point trend, +80.8% $-0.45 $-1.07 $-1.38 $-2.33 · ·
Cash / Share 5-point trend, -49.8% $0.46 $0.05 $0.67 $1.43 $0.92 ·
EPS (TTM) 5-point trend, +85.6% $-0.59 $-1.31 $-1.68 $-2.76 $-4.10 ·
Valuation (TTM) 8
Annual Valuation (TTM) data for TNYA
Metric Trend 202520242023202220212020
Net Income TTM 5-point trend, -24.6% $-91M $-111M $-124M $-124M $-73M ·
Market Cap 5-point trend, -80.3% $154M $124M $221M $134M $782M ·
P/E 5-point trend, +73.9% -1.2 -1.1 -1.9 -0.7 -4.6 ·
P/B 5-point trend, -55.4% 1.3 1.3 1.6 0.6 2.8 ·
P / Tangible Book 5-point trend, -55.4% 1.3 1.3 1.6 0.6 2.8 ·
P / Cash Flow 5-point trend, +82.4% -2.3 -1.4 -2.2 -1.3 -12.9 ·
P / FCF 5-point trend, +75.4% -2.2 -1.4 -2.1 -1.1 -9.1 ·
Earnings Yield 5-point trend, -282.9% -82.9% -91.6% -51.8% -137.3% -21.6% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-91M$-111M$-124M$-124M$-73M
Diluted EPS $-0.59$-1.31$-1.68$-2.76$-4.10
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 6.84.24.98.011.7
Quick Ratio 6.53.84.67.711.5
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-69M$-92M$-103M$-125M$-86M

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Institutional owners (13F) 116 filers · $32.3M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
24 (0 vs prior Q) 19 (+3 vs prior Q) 32 (0 vs prior Q) 17 (-3 vs prior Q) +7.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD CAPITAL MANAGEMENT LLC $5,247,833 7,101,263 16.27% Shares
MILLENNIUM MANAGEMENT LLC $4,752,153 6,429,648 14.73% Shares
RENAISSANCE TECHNOLOGIES LLC $3,164,161 4,281,100 9.81% Shares
CITADEL ADVISORS LLC $3,104,220 4,200,000 9.62% Shares
Empery Asset Management, LP $2,855,228 3,863,115 8.85% Shares
Burkehill Global Management, LP $1,478,200 2,000,000 4.58% Shares
ADAR1 Capital Management, LLC $1,149,670 1,555,500 3.56% Shares
GEODE CAPITAL MANAGEMENT, LLC $1,086,935 1,469,540 3.37% Shares
Raiffeisen Bank International AG $881,880 1,200,000 2.73% Shares
Euclidean Capital LLC $750,708 1,015,705 2.33% Shares
VANGUARD FIDUCIARY TRUST CO $729,766 987,505 2.26% Shares
Mirador Capital Partners LP $668,957 905,097 2.07% Shares
STATE STREET CORP $523,816 708,721 1.62% Shares
VANGUARD GROUP INC $495,619 696,094 1.54% Shares
Squarepoint Ops LLC $487,249 659,247 1.51% Shares
StepStone Group LP $318,892 462,163 0.99% Shares
JANE STREET GROUP, LLC $290,043 392,427 0.90% Shares
TWO SIGMA INVESTMENTS, LP $281,442 380,790 0.87% Shares
TWO SIGMA ADVISERS, LP $280,687 394,500 0.87% Shares
Casdin Capital, LLC $267,531 361,969 0.83% Shares
Invesco Ltd. $262,279 354,862 0.81% Shares
NORTHERN TRUST CORP $256,003 346,371 0.79% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $240,441 325,316 0.75% Shares
XTX Topco Ltd $231,699 313,488 0.72% Shares
DAFNA Capital Management LLC $221,730 300,000 0.69% Shares
UBS Group AG $188,116 254,555 0.58% Shares
Marex Group Ltd $174,058 235,500 0.54% Shares
CITADEL ADVISORS LLC $148,485 200,900 0.46% Call option
BRIDGEWAY CAPITAL MANAGEMENT, LLC $143,977 194,800 0.45% Shares
Almanack Investment Partners, LLC. $124,317 168,200 0.39% Shares
MARSHALL WACE, LLP $107,212 144,881 0.33% Shares
Nuveen Asset Management, LLC $99,674 69,702 0.31% Shares
CITIGROUP INC $68,305 92,417 0.21% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $66,310 76,183 0.21% Shares
GOLDMAN SACHS GROUP INC $66,149 89,500 0.21% Shares
Pathstone Holdings, LLC $55,433 75,000 0.17% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $54,020 73,000 0.17% Call option
Cetera Investment Advisers $42,221 57,125 0.13% Shares
DIMENSIONAL FUND ADVISORS LP $41,670 56,379 0.13% Shares
Vanguard Global Advisers, LLC $37,002 50,070 0.11% Shares
Callan Family Office, LLC $37,000 50,061 0.11% Shares
Integrated Wealth Concepts LLC $35,388 47,880 0.11% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $32,782 44,300 0.10% Put option
JANE STREET GROUP, LLC $31,633 42,800 0.10% Call option
Point72 Asia (Singapore) Pte. Ltd. $28,447 17,560 0.09% Shares
Spark Investment Management LLC $26,238 35,500 0.08% Shares
Vanguard Personalized Indexing Management, LLC $25,773 34,871 0.08% Shares
OSAIC HOLDINGS, INC. $25,576 34,563 0.08% Shares
China Universal Asset Management Co., Ltd. $25,525 34,535 0.08% Shares
H D Vest Advisory Services $23,531 38,500 0.07% Shares
R Squared Ltd $23,284 31,503 0.07% Shares
Integrity Wealth Solutions LLC $23,244 31,449 0.07% Shares
EWA, LLC $21,180 28,656 0.07% Shares
VICTORY CAPITAL MANAGEMENT INC $18,030 24,395 0.06% Shares
ROYAL BANK OF CANADA $18,000 24,115 0.06% Shares
Bank of New York Mellon Corp $17,742 24,005 0.06% Shares
Mariner, LLC $16,260 22,000 0.05% Shares
Quantinno Capital Management LP $15,870 21,472 0.05% Shares
HighPoint Advisor Group LLC $15,743 21,300 0.05% Shares
CITADEL ADVISORS LLC $15,447 20,900 0.05% Put option
BANK OF AMERICA CORP /DE/ $15,311 20,719 0.05% Shares
VSM Wealth Advisory, LLC $14,782 20,000 0.05% Shares
Parkwoods Wealth Partners, LLC $13,673 18,500 0.04% Shares
CITIZENS FINANCIAL GROUP INC/RI $13,304 18,000 0.04% Shares
World Investment Advisors $13,009 18,787 0.04% Shares
Federation des caisses Desjardins du Quebec $12,933 17,500 0.04% Shares
LPL Financial LLC $12,530 16,953 0.04% Shares
Peregrine Asset Advisers, Inc. $12,007 16,245 0.04% Shares
Private Advisor Group, LLC $11,899 16,100 0.04% Shares
SIMPLEX TRADING, LLC $11,849 16,035 0.04% Shares
Qube Research & Technologies Ltd $11,398 15,422 0.04% Shares
COMMERCE BANK $11,086 15,000 0.03% Shares
Northern Lights Advisors, Inc. $11,052 14,953 0.03% Shares
Spectrum Investment Advisors, Inc. $10,383 14,048 0.03% Shares
RIK SAYLOR FINANCIAL, INC. $9,978 13,500 0.03% Shares
CAPTRUST FINANCIAL ADVISORS $9,948 13,459 0.03% Shares
BARCLAYS PLC $9,715 13,145 0.03% Shares
Avior Wealth Management, LLC $9,682 13,100 0.03% Shares
Aptus Capital Advisors, LLC $8,917 12,065 0.03% Shares
ENDEAVOR PRIVATE WEALTH, INC. $8,426 11,400 0.03% Shares
Point72 Asset Management, L.P. $8,386 11,346 0.03% Shares
MML INVESTORS SERVICES, LLC $8,353 11,302 0.03% Shares
Galvin, Gaustad & Stein, LLC $8,130 11,000 0.03% Shares
Sequoia Financial Advisors, LLC $7,927 10,725 0.02% Shares
EP Wealth Advisors, LLC $7,576 10,250 0.02% Shares
PFG Investments, LLC $7,465 10,100 0.02% Shares
Quadcap Wealth Management, LLC $7,391 10,000 0.02% Shares
Mirae Asset Global Investments Co., Ltd. $7,173 9,705 0.02% Shares
Cubist Systematic Strategies, LLC $6,666 4,115 0.02% Shares
BNP PARIBAS FINANCIAL MARKETS $6,154 8,327 0.02% Shares
IFP Advisors, Inc $4,418 5,978 0.01% Shares
Ameritas Advisory Services, LLC $3,696 5,000 0.01% Shares
JPMORGAN CHASE & CO $2,265 3,082 0.01% Shares
GSA CAPITAL PARTNERS LLP $1,973 2,669,033 0.01% Shares
TFC Financial Management, Inc. $1,848 2,500 0.01% Shares
Tower Research Capital LLC (TRC) $1,774 2,400 0.01% Shares
FMR LLC $1,706 2,308 0.01% Shares
NISA INVESTMENT ADVISORS, LLC $1,664 2,252 0.01% Shares
WELLS FARGO & COMPANY/MN $1,478 2,000 0.00% Shares
SBI Securities Co., Ltd. $1,170 1,583 0.00% Shares

Company insiders 18 insiders · 5 officers · 11 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Eric J Hyllengren Chief Financial Officer July 13, 2026 A 0 0 $0
Tomohiro Higa SVP, Finance May 18, 2026 S 118,267 0 5 $-5,211
Chihiro Saito SVP, Accounting and Fin. Ops. Nov. 18, 2024 S 60,983 0 0 $0
Timothy Hoey Chief Scientific Officer March 5, 2024 S 245,346 0 0 $0
Leone D Patterson Chief Fin. and Bus. Officer Feb. 23, 2024 A 95,755 0 0 $0
Amy L. Burroughs Director May 28, 2026 A 0 0 $0
Deepak Srivastava Director May 28, 2026 A 372,435 0 0 $0
Catherine Stehman-Breen Director May 28, 2026 A 0 0 $0
June Lee Director May 28, 2026 A 0 0 $0
Karah Herdman Parschauer Director May 28, 2026 A 0 0 $0
Jeffrey T. Walsh Director May 28, 2026 A 0 0 $0
Sanders R Williams Director May 28, 2026 A 0 0 $0
David V Goeddel Director May 29, 2025 A 49,313,559 0 0 $0
Jin-Long Chen Director June 9, 2023 A 0 0 $0
Eli Casdin Director June 10, 2022 A 361,969 0 0 $0
Jeenjoo Kang Director Aug. 3, 2021 C 25,000 0 0 $0
Whittemore Tingley Aug. 17, 2026 S 214,073 0 9 $-14,865
Faraz Ali Aug. 17, 2026 S 417,782 0 9 $-32,132

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 7 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.41% 128,678 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.01% 1,540,476 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.01% 11,686 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.01% 8,012 NS May 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.01% 221,764 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 1,768,551 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 5,136,220 SH Aug. 8, 2026 Daily