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Performance as of Oct. 2, 2026

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PeriodPrice returnTotal return
1M▼ -9.84%▼ -9.78%
3M▲ +2.77%▲ +2.84%
6M▲ +34.28%▲ +34.37%
YTD▲ +37.63%▲ +37.74%
1Y▲ +73.21%▲ +73.64%
3Y▲ +135.47%▲ +142.03%
5Y▲ +20.16%▲ +23.54%
Maxsince April 9, 2010▲ +1362.31%▲ +1406.10%
Volatility 1Y42.75%
Volatility 3Y41.86%
Max drawdown 3Y -45.99% July 16, 2024 → April 8, 2025
Beta 3Y0.85
Sharpe 1Y*1.50

Total return assumes dividends are reinvested. Returns are not benchmarked against an index. * Sharpe ratio is computed with a 0% risk-free rate.

Fund flows (SEC-reported)

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Last month (May 2026) -$4.8M
Quarter ending May 2026 -$13.9M
Trailing 12 months -$12.0M Jun 2025 – May 2026

Based on the fund's own SEC Form N-PORT monthly flow disclosures (Item C.9 "Flow Information") — sales minus redemptions, reinvested distributions excluded. This is a different, independent metric from the "Net flows" estimate above (which is derived from daily shares-outstanding changes). SEC N-PORT filing lag is up to ~60 days; the most recent month/quarter may not yet be fully reflected.

Full composition 267 holdings

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NameCUSIPValue%Balance Category Country
ImmunityBio, Inc. 45256X103 $286K 0.39 38,008 EC US
Vaxcyte, Inc. 92243G108 $273K 0.37 5,321 EC US
Alkermes plc · $260K 0.35 6,163 EC IE
Immunovant, Inc. 45258J102 $251K 0.34 7,523 EC US
Kymera Therapeutics, Inc. 501575104 $246K 0.33 3,017 EC US
Protagonist Therapeutics, Inc. 74366E102 $235K 0.32 2,361 EC US
Mirum Pharmaceuticals, Inc. 604749101 $226K 0.31 2,231 EC US
PTC Therapeutics, Inc. 69366J200 $226K 0.31 3,062 EC US
Rhythm Pharmaceuticals, Inc. 76243J105 $223K 0.30 2,526 EC US
Spyre Therapeutics, Inc. 00773J202 $214K 0.29 2,905 EC US
Cogent Biosciences, Inc. 19240Q201 $210K 0.28 6,002 EC US
CRISPR Therapeutics AG · $199K 0.27 3,550 EC CH
CG oncology, Inc. 156944100 $195K 0.26 3,123 EC US
Scholar Rock Holding Corp. 80706P103 $186K 0.25 3,773 EC US
Centessa Pharmaceuticals plc 152309100 $176K 0.24 4,423 EC GB
Caris Life Sciences, Inc. 142152107 $174K 0.24 10,431 EC US
Ligand Pharmaceuticals, Inc. 53220K504 $171K 0.23 736 EC US
Xenon Pharmaceuticals, Inc. 98420N105 $168K 0.23 3,074 EC CA
Apogee Therapeutics, Inc. 03770N101 $167K 0.23 2,028 EC US
Indivior Pharmaceuticals, Inc. 45579U109 $167K 0.23 4,624 EC US
Travere Therapeutics, Inc. 89422G107 $161K 0.22 3,409 EC US
Amneal Pharmaceuticals, Inc. 03168L105 $153K 0.21 11,632 EC US
Twist Bioscience Corp. 90184D100 $152K 0.21 2,266 EC US
Erasca, Inc. 29479A108 $147K 0.20 11,444 EC US
Newamsterdam Pharma Co. NV · $143K 0.19 4,252 EC NL
Crinetics Pharmaceuticals, Inc. 22663K107 $138K 0.19 3,872 EC US
ACADIA Pharmaceuticals, Inc. 004225108 $137K 0.19 6,303 EC US
Veracyte, Inc. 92337F107 $136K 0.18 2,938 EC US
Edgewise Therapeutics, Inc. 28036F105 $135K 0.18 3,966 EC US
Beam Therapeutics, Inc. 07373V105 $124K 0.17 3,767 EC US
Denali Therapeutics, Inc. 24823R105 $123K 0.17 5,863 EC US
10X Genomics, Inc. 88025U109 $123K 0.17 4,351 EC US
Dyne Therapeutics, Inc. 26818M108 $118K 0.16 6,087 EC US
Structure Therapeutics, Inc. 86366E106 $113K 0.15 2,880 EC KY
Tango Therapeutics, Inc. 87583X109 $109K 0.15 4,978 EC US
Oruka Therapeutics, Inc. 687604108 $105K 0.14 1,789 EC US
GRAIL, Inc. 384747101 $103K 0.14 1,439 EC US
Alumis, Inc. 022307102 $101K 0.14 4,674 EC US
Arcutis Biotherapeutics, Inc. 03969K108 $98K 0.13 4,587 EC US
Disc Medicine, Inc. 254604101 $98K 0.13 1,411 EC US
Supernus Pharmaceuticals, Inc. 868459108 $98K 0.13 2,120 EC US
Ideaya Biosciences, Inc. 45166A102 $96K 0.13 3,246 EC US
Vera Therapeutics, Inc. 92337R101 $94K 0.13 2,636 EC US
Tarsus Pharmaceuticals, Inc. 87650L103 $93K 0.13 1,573 EC US
Relay Therapeutics, Inc. 75943R102 $93K 0.13 6,606 EC US
Mineralys Therapeutics, Inc. 603170101 $92K 0.13 2,925 EC US
Definium Therapeutics, Inc. 24477V105 $89K 0.12 3,685 EC CA
Enliven Therapeutics, Inc. 29337E102 $87K 0.12 2,196 EC US
Adaptive Biotechnologies Corp. 00650F109 $86K 0.12 5,692 EC US
Ultragenyx Pharmaceutical, Inc. 90400D108 $85K 0.12 3,571 EC US

Dividends 13 payments

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0.20%TTM yield
$0.23TTM payout / share
Quarterly (est.)
Ex-dateAmount / share
Sept. 23, 2026$0.0830
March 25, 2026$0.0070
Dec. 24, 2025$0.1350
Sept. 24, 2025$0.1810
June 25, 2025$0.1710
March 26, 2025$0.1310
Dec. 23, 2024$0.3960
Sept. 25, 2024$0.1530
June 26, 2024$0.2650
March 20, 2024$0.0400
Dec. 20, 2023$0.0380
Dec. 22, 2022$0.0200
Sept. 21, 2010$0.0110

Institutional owners (13F) 22 filers

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Institutions that report holding this ETF in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institution Value % of tracked 13F Shares Type As of
SUSQUEHANNA INTERNATIONAL GROUP, LLP $785,973 21.94% 7,802 Shares June 30, 2026
Capital Investment Advisors, LLC $599,013 16.72% 5,946 Shares June 30, 2026
Kaizen Financial Strategies $535,554 14.95% 5,315 Shares June 30, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP $413,034 11.53% 4,100 Call option June 30, 2026
Palumbo Wealth Management LLC $402,960 11.25% 4,000 Shares June 30, 2026
CITADEL ADVISORS LLC $302,220 8.44% 3,000 Call option June 30, 2026
Jump Financial, LLC $257,189 7.18% 2,553 Shares June 30, 2026
TOTH FINANCIAL ADVISORY CORP $102,957 2.87% 1,022 Shares June 30, 2026
FRANKLIN RESOURCES INC $70,115 1.96% 696 Shares June 30, 2026
PNC Financial Services Group, Inc. $50,370 1.41% 500 Shares June 30, 2026
Ashton Thomas Private Wealth, LLC $37,576 1.05% 373 Shares June 30, 2026
Truvestments Capital LLC $12,593 0.35% 125 Shares June 30, 2026
Axiom Investment Management LLC $5,037 0.14% 50 Shares June 30, 2026
Qube Research & Technologies Ltd $4,936 0.14% 49 Shares June 30, 2026
SIMPLEX TRADING, LLC $1,309 0.04% 13 Shares June 30, 2026
CHASE INVESTMENT COUNSEL CORP $241 0.01% 2,400 Shares June 30, 2026
Rockefeller Capital Management L.P. $201 0.01% 2 Shares June 30, 2026
MORGAN STANLEY $131 0.00% 1 Shares June 30, 2026
UBS Group AG $101 0.00% 1 Shares June 30, 2026
WELLS FARGO & COMPANY/MN $65 0.00% 1 Shares June 30, 2026
Harel Insurance Investments & Financial Services Ltd. $20 0.00% 198 Shares June 30, 2026
ROYAL BANK OF CANADA $0 0.00% 1 Shares June 30, 2026

Peer funds

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