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Performance as of Oct. 2, 2026

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PeriodPrice returnTotal return
1M▼ -9.84%▼ -9.78%
3M▲ +2.77%▲ +2.84%
6M▲ +34.28%▲ +34.37%
YTD▲ +37.63%▲ +37.74%
1Y▲ +73.21%▲ +73.64%
3Y▲ +135.47%▲ +142.03%
5Y▲ +20.16%▲ +23.54%
Maxsince April 9, 2010▲ +1362.31%▲ +1406.10%
Volatility 1Y42.75%
Volatility 3Y41.86%
Max drawdown 3Y -45.99% July 16, 2024 → April 8, 2025
Beta 3Y0.85
Sharpe 1Y*1.50

Total return assumes dividends are reinvested. Returns are not benchmarked against an index. * Sharpe ratio is computed with a 0% risk-free rate.

Fund flows (SEC-reported)

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Last month (May 2026) -$4.8M
Quarter ending May 2026 -$13.9M
Trailing 12 months -$12.0M Jun 2025 – May 2026

Based on the fund's own SEC Form N-PORT monthly flow disclosures (Item C.9 "Flow Information") — sales minus redemptions, reinvested distributions excluded. This is a different, independent metric from the "Net flows" estimate above (which is derived from daily shares-outstanding changes). SEC N-PORT filing lag is up to ~60 days; the most recent month/quarter may not yet be fully reflected.

Full composition 267 holdings

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NameCUSIPValue%Balance Category Country
Legend Biotech Corp. 52490G102 $85K 0.12 3,122 EC KY
Kodiak Sciences, Inc. 50015M109 $83K 0.11 2,255 EC US
BioCryst Pharmaceuticals, Inc. 09058V103 $83K 0.11 9,271 EC US
Kiniksa Pharmaceuticals International plc · $82K 0.11 1,698 EC GB
Aurinia Pharmaceuticals, Inc. 05156V102 $75K 0.10 4,914 EC CA
Ocular Therapeutix, Inc. 67576A100 $73K 0.10 8,049 EC US
Novocure Ltd. · $72K 0.10 4,209 EC JE
Pharvaris NV · $71K 0.10 2,367 EC NL
Sionna Therapeutics, Inc. 829401108 $71K 0.10 1,651 EC US
ADMA Biologics, Inc. 000899104 $70K 0.10 8,805 EC US
Rapport Therapeutics, Inc. 75383L102 $70K 0.09 1,764 EC US
Zymeworks, Inc. 98985Y108 $70K 0.09 2,766 EC US
Recursion Pharmaceuticals, Inc. 75629V104 $69K 0.09 19,297 EC US
Sarepta Therapeutics, Inc. 803607100 $69K 0.09 3,875 EC US
AbCellera Biologics, Inc. 00288U106 $69K 0.09 11,209 EC CA
Harmony Biosciences Holdings, Inc. 413197104 $68K 0.09 2,140 EC US
Nurix Therapeutics, Inc. 67080M103 $68K 0.09 3,802 EC US
Trevi Therapeutics, Inc. 89532M101 $67K 0.09 4,742 EC US
Novavax, Inc. 670002401 $66K 0.09 6,023 EC US
Tyra Biosciences, Inc. 90240B106 $66K 0.09 1,974 EC US
uniQure NV · $66K 0.09 2,305 EC NL
Stoke Therapeutics, Inc. 86150R107 $65K 0.09 2,111 EC US
ANI Pharmaceuticals, Inc. 00182C103 $65K 0.09 830 EC US
Syndax Pharmaceuticals, Inc. 87164F105 $64K 0.09 3,261 EC US
Agios Pharmaceuticals, Inc. 00847X104 $64K 0.09 2,166 EC US
Genmab A/S 372303206 $63K 0.09 2,379 EC DK
Vericel Corp. 92346J108 $62K 0.08 1,875 EC US
Iovance Biotherapeutics, Inc. 462260100 $62K 0.08 15,232 EC US
Intellia Therapeutics, Inc. 45826J105 $61K 0.08 4,369 EC US
AtaiBeckley, Inc. 04650F101 $61K 0.08 13,429 EC US
Taysha Gene Therapies, Inc. 877619106 $59K 0.08 10,128 EC US
Innoviva, Inc. 45781M101 $59K 0.08 2,740 EC US
Amylyx Pharmaceuticals, Inc. 03237H101 $58K 0.08 4,059 EC US
AnaptysBio, Inc. 032724106 $57K 0.08 1,023 EC US
Precigen, Inc. 74017N105 $57K 0.08 13,080 EC US
Inhibrx Biosciences, Inc. 45720N103 $56K 0.08 537 EC US
Monte Rosa Therapeutics, Inc. 61225M102 $56K 0.08 2,818 EC US
Vir Biotechnology, Inc. 92764N102 $55K 0.08 5,810 EC US
GH Research plc · $55K 0.07 2,294 EC IE
Ardelyx, Inc. 039697107 $55K 0.07 9,066 EC US
Fortrea Holdings, Inc. 34965K107 $53K 0.07 3,455 EC US
MBX Biosciences, Inc. 55287L101 $52K 0.07 1,658 EC US
Bicara Therapeutics, Inc. 055477103 $51K 0.07 2,343 EC US
KalVista Pharmaceuticals, Inc. 483497103 $50K 0.07 1,870 EC US
Septerna, Inc. 81734D104 $50K 0.07 1,657 EC US
UroGen Pharma Ltd. · $49K 0.07 1,730 EC IL
Harrow, Inc. 415858109 $48K 0.07 1,370 EC US
Maze Therapeutics, Inc. 578784100 $47K 0.06 1,778 EC US
Immunocore Holdings plc 45258D105 $47K 0.06 1,621 EC GB
ArriVent Biopharma, Inc. 04272N102 $46K 0.06 1,527 EC US

Dividends 13 payments

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0.20%TTM yield
$0.23TTM payout / share
Quarterly (est.)
Ex-dateAmount / share
Sept. 23, 2026$0.0830
March 25, 2026$0.0070
Dec. 24, 2025$0.1350
Sept. 24, 2025$0.1810
June 25, 2025$0.1710
March 26, 2025$0.1310
Dec. 23, 2024$0.3960
Sept. 25, 2024$0.1530
June 26, 2024$0.2650
March 20, 2024$0.0400
Dec. 20, 2023$0.0380
Dec. 22, 2022$0.0200
Sept. 21, 2010$0.0110

Institutional owners (13F) 22 filers

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Institutions that report holding this ETF in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institution Value % of tracked 13F Shares Type As of
SUSQUEHANNA INTERNATIONAL GROUP, LLP $785,973 21.94% 7,802 Shares June 30, 2026
Capital Investment Advisors, LLC $599,013 16.72% 5,946 Shares June 30, 2026
Kaizen Financial Strategies $535,554 14.95% 5,315 Shares June 30, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP $413,034 11.53% 4,100 Call option June 30, 2026
Palumbo Wealth Management LLC $402,960 11.25% 4,000 Shares June 30, 2026
CITADEL ADVISORS LLC $302,220 8.44% 3,000 Call option June 30, 2026
Jump Financial, LLC $257,189 7.18% 2,553 Shares June 30, 2026
TOTH FINANCIAL ADVISORY CORP $102,957 2.87% 1,022 Shares June 30, 2026
FRANKLIN RESOURCES INC $70,115 1.96% 696 Shares June 30, 2026
PNC Financial Services Group, Inc. $50,370 1.41% 500 Shares June 30, 2026
Ashton Thomas Private Wealth, LLC $37,576 1.05% 373 Shares June 30, 2026
Truvestments Capital LLC $12,593 0.35% 125 Shares June 30, 2026
Axiom Investment Management LLC $5,037 0.14% 50 Shares June 30, 2026
Qube Research & Technologies Ltd $4,936 0.14% 49 Shares June 30, 2026
SIMPLEX TRADING, LLC $1,309 0.04% 13 Shares June 30, 2026
CHASE INVESTMENT COUNSEL CORP $241 0.01% 2,400 Shares June 30, 2026
Rockefeller Capital Management L.P. $201 0.01% 2 Shares June 30, 2026
MORGAN STANLEY $131 0.00% 1 Shares June 30, 2026
UBS Group AG $101 0.00% 1 Shares June 30, 2026
WELLS FARGO & COMPANY/MN $65 0.00% 1 Shares June 30, 2026
Harel Insurance Investments & Financial Services Ltd. $20 0.00% 198 Shares June 30, 2026
ROYAL BANK OF CANADA $0 0.00% 1 Shares June 30, 2026

Peer funds

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