DSGN — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| SR One Capital Management, LP | $94 438 108 | 6 526 476 | 14,39% | Actions |
| Logos Global Management LP | $43 410 000 | 3 000 000 | 6,62% | Actions |
| BAKER BROS. ADVISORS LP | $38 756 882 | 2 678 430 | 5,91% | Actions |
| Driehaus Capital Management LLC | $38 506 334 | 2 661 115 | 5,87% | Actions |
| BlackRock, Inc. | $38 490 551 | 2 660 024 | 5,87% | Actions |
| Point72 Asset Management, L.P. | $34 242 575 | 2 366 453 | 5,22% | Actions |
| Trails Edge Capital Partners, LP | $28 958 550 | 2 001 282 | 4,41% | Actions |
| Frazier Life Sciences Management, L.P. | $26 188 587 | 1 809 854 | 3,99% | Actions |
| Vivo Capital, LLC | $23 338 706 | 1 612 903 | 3,56% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $22 732 688 | 1 571 022 | 3,46% | Actions |
| Caption Management, LLC | $21 705 000 | 1 500 000 | 3,31% | Option d'achat |
| Caption Management, LLC | $16 178 878 | 1 118 098 | 2,47% | Actions |
| VANGUARD GROUP INC | $15 297 936 | 1 630 910 | 2,33% | Actions |
| Almitas Capital LLC | $14 859 142 | 1 026 893 | 2,26% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $13 871 597 | 958 417 | 2,11% | Actions |
| Sofinnova Investments, Inc. | $12 518 503 | 865 135 | 1,91% | Actions |
| FMR LLC | $11 235 405 | 776 462 | 1,71% | Actions |
| MORGAN STANLEY | $11 075 699 | 765 425 | 1,69% | Actions |
| STATE STREET CORP | $10 653 118 | 736 221 | 1,62% | Actions |
| Woodline Partners LP | $10 134 122 | 700 354 | 1,54% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $10 051 800 | 694 743 | 1,53% | Actions |
| GOLDMAN SACHS GROUP INC | $9 500 771 | 656 584 | 1,45% | Actions |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $8 184 189 | 565 597 | 1,25% | Actions |
| Siren, L.L.C. | $7 570 878 | 523 212 | 1,15% | Actions |
| Qube Research & Technologies Ltd | $6 324 533 | 437 079 | 0,96% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $5 613 101 | 387 913 | 0,86% | Actions |
| KENNEDY CAPITAL MANAGEMENT LLC | $5 557 001 | 384 036 | 0,85% | Actions |
| NORTHERN TRUST CORP | $5 110 762 | 353 197 | 0,78% | Actions |
| ALGERT GLOBAL LLC | $4 284 350 | 296 085 | 0,65% | Actions |
| ACUTA CAPITAL PARTNERS, LLC | $4 088 701 | 282 564 | 0,62% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3 925 190 | 271 264 | 0,60% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3 638 366 | 251 442 | 0,55% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $3 331 023 | 230 202 | 0,51% | Actions |
| PRUDENTIAL FINANCIAL INC | $3 243 740 | 224 170 | 0,49% | Actions |
| D. E. Shaw & Co., Inc. | $2 830 983 | 195 645 | 0,43% | Actions |
| Eversept Partners, LP | $2 749 300 | 190 000 | 0,42% | Actions |
| KVP Capital Advisors, LP | $2 676 950 | 185 000 | 0,41% | Actions |
| J. Goldman & Co LP | $2 557 862 | 176 770 | 0,39% | Actions |
| MILLENNIUM MANAGEMENT LLC | $2 137 422 | 147 714 | 0,33% | Actions |
| RAYMOND JAMES FINANCIAL INC | $2 004 399 | 138 521 | 0,31% | Actions |
| Balyasny Asset Management L.P. | $1 607 660 | 111 103 | 0,25% | Actions |
| Elmind Capital, LP | $1 561 313 | 107 900 | 0,24% | Actions |
| Nuveen, LLC | $1 515 501 | 104 734 | 0,23% | Actions |
| DAFNA Capital Management LLC | $1 484 622 | 102 600 | 0,23% | Actions |
| Bank of New York Mellon Corp | $1 332 238 | 92 069 | 0,20% | Actions |
| China Universal Asset Management Co., Ltd. | $1 301 432 | 89 940 | 0,20% | Actions |
| CITADEL ADVISORS LLC | $1 186 120 | 81 971 | 0,18% | Actions |
| SummitTX Capital, L.P. | $1 167 194 | 80 663 | 0,18% | Actions |
| AMERICAN CENTURY COMPANIES INC | $1 111 658 | 76 825 | 0,17% | Actions |
| Palumbo Wealth Management LLC | $1 038 136 | 71 744 | 0,16% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $1 029 019 | 71 114 | 0,16% | Actions |
| AMERIPRISE FINANCIAL INC | $978 143 | 67 598 | 0,15% | Actions |
| Russell Investments Group, Ltd. | $967 448 | 66 859 | 0,15% | Actions |
| ALPS ADVISORS INC | $917 268 | 63 391 | 0,14% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $857 333 | 59 249 | 0,13% | Actions |
| STRS OHIO | $730 735 | 50 500 | 0,11% | Actions |
| Verdad Advisers, LP | $688 150 | 47 557 | 0,10% | Actions |
| BANK OF AMERICA CORP /DE/ | $632 745 | 43 728 | 0,10% | Actions |
| ExodusPoint Capital Management, LP | $597 408 | 41 286 | 0,09% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $578 800 | 40 000 | 0,09% | Option d'achat |
| RHUMBLINE ADVISERS | $551 760 | 38 132 | 0,08% | Actions |
| Vanguard Global Advisers, LLC | $514 177 | 35 534 | 0,08% | Actions |
| UBS Group AG | $502 992 | 34 761 | 0,08% | Actions |
| Susquehanna Portfolio Strategies, LLC | $482 936 | 33 375 | 0,07% | Actions |
| TWO SIGMA INVESTMENTS, LP | $476 425 | 32 925 | 0,07% | Actions |
| CANADA PENSION PLAN INVESTMENT BOARD | $471 722 | 32 600 | 0,07% | Actions |
| OPPENHEIMER & CO INC | $464 299 | 32 087 | 0,07% | Actions |
| ALLIANCEBERNSTEIN L.P. | $459 967 | 43 230 | 0,07% | Actions |
| DEUTSCHE BANK AG\ | $442 970 | 30 613 | 0,07% | Actions |
| Virtus Investment Advisers, LLC | $431 597 | 29 827 | 0,07% | Actions |
| Squarepoint Ops LLC | $428 746 | 29 630 | 0,07% | Actions |
| Trexquant Investment LP | $407 331 | 28 150 | 0,06% | Actions |
| WELLS FARGO & COMPANY/MN | $406 202 | 28 072 | 0,06% | Actions |
| Corient Private Wealth LP | $393 136 | 27 169 | 0,06% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $390 690 | 27 000 | 0,06% | Actions |
| Quantinno Capital Management LP | $389 257 | 26 901 | 0,06% | Actions |
| SEI INVESTMENTS CO | $329 053 | 22 740 | 0,05% | Actions |
| XTX Topco Ltd | $323 882 | 22 383 | 0,05% | Actions |
| AlphaCentric Advisors LLC | $311 640 | 21 537 | 0,05% | Actions |
| Invesco Ltd. | $310 078 | 21 429 | 0,05% | Actions |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $299 529 | 20 700 | 0,05% | Actions |
| MetLife Investment Management, LLC | $298 212 | 20 609 | 0,05% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $280 718 | 19 400 | 0,04% | Actions |
| JPMORGAN CHASE & CO | $240 713 | 16 904 | 0,04% | Actions |
| TWO SIGMA ADVISERS, LP | $237 314 | 25 300 | 0,04% | Actions |
| CITIGROUP INC | $229 784 | 15 880 | 0,04% | Actions |
| Creative Planning | $229 263 | 15 844 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $226 456 | 15 650 | 0,03% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $214 503 | 14 824 | 0,03% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $205 054 | 14 171 | 0,03% | Actions |
| CITADEL ADVISORS LLC | $201 133 | 13 900 | 0,03% | Option d'achat |
| Y-Intercept (Hong Kong) Ltd | $186 808 | 12 910 | 0,03% | Actions |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $181 642 | 12 553 | 0,03% | Actions |
| ROYAL BANK OF CANADA | $178 000 | 12 254 | 0,03% | Actions |
| BARCLAYS PLC | $169 401 | 11 707 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $156 652 | 10 826 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $142 515 | 9 849 | 0,02% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $83 217 | 5 751 | 0,01% | Actions |
| Clearstead Advisors, LLC | $81 177 | 5 610 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $71 019 | 4 908 | 0,01% | Actions |
| Rockefeller Capital Management L.P. | $53 308 | 3 684 | 0,01% | Actions |
| CAZ INVESTMENTS LP | $50 645 | 3 500 | 0,01% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $43 772 | 3 025 | 0,01% | Actions |
| Legal & General Group Plc | $43 222 | 2 987 | 0,01% | Actions |
| Point72 Asia (Singapore) Pte. Ltd. | $42 940 | 5 702 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $40 415 | 2 793 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $40 415 | 2 793 | 0,01% | Actions |
| State of Wyoming | $37 130 | 2 566 | 0,01% | Actions |
| PNC Financial Services Group, Inc. | $26 277 | 1 816 | 0,00% | Actions |
| GAMMA Investing LLC | $20 982 | 1 450 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $18 218 | 1 259 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $17 494 | 1 209 | 0,00% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $12 162 | 1 143 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $7 774 | 537 479 | 0,00% | Actions |
| Private Wealth Management Group, LLC | $7 713 | 533 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $4 847 | 335 | 0,00% | Actions |
| CWM, LLC | $4 501 | 423 | 0,00% | Actions |
| Physician Wealth Advisors, Inc. | $3 878 | 268 | 0,00% | Actions |
| MassMutual Private Wealth & Trust, FSB | $3 458 | 239 | 0,00% | Actions |
| Stone House Investment Management, LLC | $3 458 | 239 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $3 255 | 225 | 0,00% | Actions |
| Larson Financial Group LLC | $2 619 | 181 | 0,00% | Actions |
| Arax Advisory Partners | $2 606 | 180 | 0,00% | Actions |
| SIMPLEX TRADING, LLC | $2 488 | 172 | 0,00% | Actions |
| Optiver Holding B.V. | $2 315 | 160 | 0,00% | Actions |
| Sterling Capital Management LLC | $1 563 | 108 | 0,00% | Actions |
| Allworth Financial LP | $1 390 | 96 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $1 199 | 83 | 0,00% | Actions |
| Versant Capital Management, Inc | $1 081 | 86 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $839 | 58 | 0,00% | Actions |
| Quarry LP | $449 | 31 | 0,00% | Actions |
| US BANCORP \DE\ | $376 | 26 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $371 | 25 606 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $362 | 25 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $318 | 22 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $289 | 20 | 0,00% | Actions |
| True Wealth Design, LLC | $261 | 18 | 0,00% | Actions |
| GSA CAPITAL PARTNERS LLP | $149 | 10 328 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $145 | 10 | 0,00% | Actions |
| SJS Investment Consulting Inc. | $58 | 4 | 0,00% | Actions |
| Essential Partners LLC | $14 | 1 | 0,00% | Actions |
| Capital Advisors, Ltd. LLC | $0 | 12 | 0,00% | Actions |