GLUE — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| NEA Management Company, LLC | $186 153 612 | 7 692 298 | 9,04% | Actions |
| BlackRock, Inc. | $165 602 706 | 6 843 087 | 8,05% | Actions |
| TCG Crossover Management, LLC | $111 856 054 | 4 622 151 | 5,43% | Actions |
| Vestal Point Capital, LP | $111 320 000 | 4 600 000 | 5,41% | Actions |
| BVF INC/IL | $107 953 441 | 4 460 886 | 5,25% | Actions |
| BAKER BROS. ADVISORS LP | $105 166 811 | 4 345 736 | 5,11% | Actions |
| STATE STREET CORP | $90 300 267 | 3 731 416 | 4,39% | Actions |
| MONTANOVA CAPITAL, LLC | $85 898 844 | 3 549 539 | 4,17% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $82 592 833 | 3 412 927 | 4,01% | Actions |
| Versant Venture Management, LLC | $76 974 876 | 3 180 780 | 3,74% | Actions |
| BRAIDWELL LP | $59 327 800 | 2 451 562 | 2,88% | Actions |
| VANGUARD GROUP INC | $50 905 120 | 3 246 500 | 2,47% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $45 121 645 | 1 864 113 | 2,19% | Actions |
| AMERICAN CENTURY COMPANIES INC | $39 272 873 | 1 622 846 | 1,91% | Actions |
| MARSHALL WACE, LLP | $38 565 119 | 1 593 600 | 1,87% | Actions |
| Aisling Capital Management LP | $37 647 069 | 1 555 664 | 1,83% | Actions |
| Bellevue Group AG | $28 798 000 | 1 190 000 | 1,40% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $28 493 337 | 1 177 488 | 1,38% | Actions |
| MPM BIOIMPACT LLC | $28 098 160 | 1 161 081 | 1,37% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $26 820 739 | 1 108 295 | 1,30% | Actions |
| Frazier Life Sciences Management, L.P. | $24 200 000 | 1 000 000 | 1,18% | Actions |
| GOLDMAN SACHS GROUP INC | $24 157 723 | 998 253 | 1,17% | Actions |
| Woodline Partners LP | $23 301 793 | 962 884 | 1,13% | Actions |
| FMR LLC | $22 612 829 | 934 414 | 1,10% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $19 164 754 | 791 932 | 0,93% | Actions |
| MORGAN STANLEY | $19 106 990 | 789 545 | 0,93% | Actions |
| Nextech Invest Ltd. | $18 419 903 | 761 153 | 0,90% | Actions |
| Opaleye Management Inc. | $18 029 000 | 745 000 | 0,88% | Actions |
| NORTHERN TRUST CORP | $15 780 505 | 652 087 | 0,77% | Actions |
| Nantahala Capital Management, LLC | $15 778 231 | 651 993 | 0,77% | Actions |
| FIRST TRUST ADVISORS LP | $15 676 663 | 647 796 | 0,76% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14 914 702 | 616 310 | 0,72% | Actions |
| BOONE CAPITAL MANAGEMENT LLC | $14 889 945 | 615 287 | 0,72% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $13 372 097 | 552 566 | 0,65% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $12 599 682 | 520 648 | 0,61% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $12 233 100 | 505 500 | 0,59% | Actions |
| JANUS HENDERSON GROUP PLC | $11 293 772 | 685 926 | 0,55% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $10 890 000 | 450 000 | 0,53% | Actions |
| KENNEDY CAPITAL MANAGEMENT LLC | $9 813 802 | 405 529 | 0,48% | Actions |
| AMERIPRISE FINANCIAL INC | $9 276 708 | 383 335 | 0,45% | Actions |
| Alphabet Inc. | $9 013 871 | 372 474 | 0,44% | Actions |
| Fisher Asset Management, LLC | $8 797 182 | 363 520 | 0,43% | Actions |
| Allspring Global Investments Holdings, LLC | $8 539 139 | 352 857 | 0,41% | Actions |
| Empowered Funds, LLC | $7 968 237 | 329 266 | 0,39% | Actions |
| Caption Management, LLC | $7 260 000 | 300 000 | 0,35% | Option d'achat |
| TD Asset Management Inc | $6 919 651 | 285 936 | 0,34% | Actions |
| BANK OF AMERICA CORP /DE/ | $6 160 376 | 254 561 | 0,30% | Actions |
| Bank of New York Mellon Corp | $5 385 007 | 222 521 | 0,26% | Actions |
| Longaeva Partners L.P. | $5 246 366 | 216 792 | 0,25% | Actions |
| ADAR1 Capital Management, LLC | $5 245 398 | 216 752 | 0,25% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $5 019 734 | 207 427 | 0,24% | Actions |
| UBS Group AG | $4 860 159 | 200 833 | 0,24% | Actions |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $4 840 000 | 200 000 | 0,24% | Actions |
| Balyasny Asset Management L.P. | $4 813 259 | 198 895 | 0,23% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $4 643 423 | 191 877 | 0,23% | Actions |
| FRANKLIN RESOURCES INC | $4 569 759 | 188 833 | 0,22% | Actions |
| Casdin Capital, LLC | $4 501 539 | 186 014 | 0,22% | Actions |
| D. E. Shaw & Co., Inc. | $4 163 683 | 172 053 | 0,20% | Actions |
| DIADEMA PARTNERS LP | $4 116 420 | 170 100 | 0,20% | Option d'achat |
| VICTORY CAPITAL MANAGEMENT INC | $4 077 990 | 168 512 | 0,20% | Actions |
| Nuveen, LLC | $4 035 544 | 166 758 | 0,20% | Actions |
| CITADEL ADVISORS LLC | $3 958 418 | 163 571 | 0,19% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $3 790 518 | 156 633 | 0,18% | Actions |
| STEMPOINT CAPITAL LP | $3 715 765 | 153 544 | 0,18% | Actions |
| TWO SIGMA INVESTMENTS, LP | $3 410 337 | 140 923 | 0,17% | Actions |
| Exome Asset Management LLC | $3 318 183 | 137 115 | 0,16% | Actions |
| CITIGROUP INC | $3 133 102 | 129 467 | 0,15% | Actions |
| ExodusPoint Capital Management, LP | $2 931 128 | 121 121 | 0,14% | Actions |
| Trexquant Investment LP | $2 791 785 | 115 363 | 0,14% | Actions |
| Caption Management, LLC | $2 718 192 | 112 322 | 0,13% | Actions |
| Atom Investors LP | $2 686 490 | 111 012 | 0,13% | Actions |
| Jain Global LLC | $2 677 657 | 110 647 | 0,13% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $2 480 500 | 102 500 | 0,12% | Actions |
| Invesco Ltd. | $2 347 714 | 97 013 | 0,11% | Actions |
| Swiss National Bank | $2 330 460 | 96 300 | 0,11% | Actions |
| RHUMBLINE ADVISERS | $2 289 140 | 94 593 | 0,11% | Actions |
| Squarepoint Ops LLC | $2 007 463 | 82 953 | 0,10% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1 914 752 | 79 122 | 0,09% | Actions |
| DIADEMA PARTNERS LP | $1 897 062 | 78 391 | 0,09% | Actions |
| JPMORGAN CHASE & CO | $1 835 998 | 76 820 | 0,09% | Actions |
| DEUTSCHE BANK AG\ | $1 816 477 | 75 061 | 0,09% | Actions |
| WELLS FARGO & COMPANY/MN | $1 661 330 | 68 650 | 0,08% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 614 285 | 66 706 | 0,08% | Actions |
| ALLIANCEBERNSTEIN L.P. | $1 438 059 | 87 420 | 0,07% | Actions |
| Rafferty Asset Management, LLC | $1 421 871 | 58 755 | 0,07% | Actions |
| Tetragon Partners GP Ltd | $1 356 458 | 56 052 | 0,07% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $1 314 738 | 54 328 | 0,06% | Actions |
| Quantinno Capital Management LP | $1 311 616 | 54 199 | 0,06% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 311 543 | 54 196 | 0,06% | Actions |
| SEI INVESTMENTS CO | $1 210 681 | 50 028 | 0,06% | Actions |
| PRINCIPAL FINANCIAL GROUP INC | $1 185 824 | 49 001 | 0,06% | Actions |
| SEVEN GRAND MANAGERS, LLC | $1 089 000 | 45 000 | 0,05% | Actions |
| MetLife Investment Management, LLC | $1 053 402 | 43 529 | 0,05% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 043 020 | 43 100 | 0,05% | Option de vente |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $988 290 | 40 923 | 0,05% | Actions |
| Legal & General Group Plc | $977 099 | 40 376 | 0,05% | Actions |
| XTX Topco Ltd | $964 975 | 39 875 | 0,05% | Actions |
| Russell Investments Group, Ltd. | $938 336 | 38 774 | 0,05% | Actions |
| Vanguard Global Advisers, LLC | $934 967 | 38 635 | 0,05% | Actions |
| Round Rock Advisors LLC | $900 942 | 37 229 | 0,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $885 720 | 36 600 | 0,04% | Option d'achat |
| ACT CAPITAL MANAGEMENT, LLC | $847 000 | 35 000 | 0,04% | Actions |
| Jump Financial, LLC | $844 580 | 34 900 | 0,04% | Actions |
| BARCLAYS PLC | $834 102 | 34 467 | 0,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $829 600 | 34 281 | 0,04% | Actions |
| Persistent Asset Partners Ltd | $824 808 | 34 083 | 0,04% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $816 314 | 33 732 | 0,04% | Actions |
| Arax Advisory Partners | $773 311 | 31 955 | 0,04% | Actions |
| ADVISORY RESEARCH INC | $759 783 | 31 396 | 0,04% | Actions |
| Aquatic Capital Management LLC | $739 310 | 30 550 | 0,04% | Actions |
| Informed Momentum Co LLC | $736 067 | 30 416 | 0,04% | Actions |
| PROFUND ADVISORS LLC | $728 686 | 30 111 | 0,04% | Actions |
| Campbell & CO Investment Adviser LLC | $686 675 | 28 375 | 0,03% | Actions |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $663 104 | 27 401 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $628 571 | 25 974 | 0,03% | Actions |
| Harvest Investment Services, LLC | $613 543 | 25 353 | 0,03% | Actions |
| Y-Intercept (Hong Kong) Ltd | $608 606 | 25 149 | 0,03% | Actions |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $597 220 | 25 921 | 0,03% | Actions |
| PSP Research LLC | $556 600 | 23 000 | 0,03% | Actions |
| Creative Planning | $549 969 | 22 726 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $528 528 | 21 840 | 0,03% | Actions |
| Verition Fund Management LLC | $496 100 | 20 500 | 0,02% | Actions |
| CWM, LLC | $488 351 | 29 687 | 0,02% | Actions |
| DLD Asset Management, LP | $484 200 | 20 000 | 0,02% | Option d'achat |
| Corient Private Wealth LP | $462 704 | 19 120 | 0,02% | Actions |
| IEQ CAPITAL, LLC | $458 808 | 18 959 | 0,02% | Actions |
| AlphaQuest LLC | $444 089 | 28 322 | 0,02% | Actions |
| Virtus Investment Advisers, LLC | $434 245 | 17 944 | 0,02% | Actions |
| Seven Fleet Capital Management LP | $406 560 | 16 800 | 0,02% | Actions |
| TEMA ETFS LLC | $388 347 | 24 767 | 0,02% | Actions |
| State of New Jersey Common Pension Fund D | $375 657 | 15 523 | 0,02% | Actions |
| HighTower Advisors, LLC | $370 526 | 15 311 | 0,02% | Actions |
| J. Goldman & Co LP | $365 880 | 15 119 | 0,02% | Actions |
| China Universal Asset Management Co., Ltd. | $364 089 | 15 045 | 0,02% | Actions |
| FOX RUN MANAGEMENT, L.L.C. | $360 169 | 14 883 | 0,02% | Actions |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. | $354 796 | 14 661 | 0,02% | Actions |
| State of Wyoming | $344 003 | 14 215 | 0,02% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $335 969 | 13 883 | 0,02% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $328 346 | 13 568 | 0,02% | Actions |
| ARIZONA STATE RETIREMENT SYSTEM | $320 577 | 13 247 | 0,02% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $317 140 | 19 279 | 0,02% | Actions |
| AlphaCentric Advisors LLC | $306 009 | 12 645 | 0,01% | Actions |
| MANGROVE PARTNERS IM, LLC | $302 911 | 12 517 | 0,01% | Actions |
| ProShare Advisors LLC | $301 581 | 12 462 | 0,01% | Actions |
| AXQ CAPITAL, LP | $296 934 | 12 270 | 0,01% | Actions |
| PRUDENTIAL FINANCIAL INC | $289 795 | 11 975 | 0,01% | Actions |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $273 460 | 11 300 | 0,01% | Actions |
| KLP KAPITALFORVALTNING AS | $263 780 | 10 900 | 0,01% | Actions |
| Persistent Asset Partners Ltd | $258 066 | 434 | 0,01% | Option d'achat |
| MERCER GLOBAL ADVISORS INC /ADV | $257 270 | 10 631 | 0,01% | Actions |
| WEALTH EFFECTS LLC | $244 396 | 10 099 | 0,01% | Actions |
| Mayflower Financial Advisors, LLC | $242 000 | 10 000 | 0,01% | Actions |
| BRIGHTON JONES LLC | $235 854 | 9 746 | 0,01% | Actions |
| JANE STREET GROUP, LLC | $225 060 | 9 300 | 0,01% | Option de vente |
| Pallas Capital Advisors LLC | $221 140 | 9 138 | 0,01% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $214 442 | 8 861 171 | 0,01% | Actions |
| Vanguard Investments Australia, Ltd. | $214 194 | 8 851 | 0,01% | Actions |
| CITADEL ADVISORS LLC | $212 960 | 8 800 | 0,01% | Option d'achat |
| E Fund Management Co., Ltd. | $200 497 | 8 285 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $162 624 | 6 720 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $148 588 | 6 140 | 0,01% | Actions |
| Rockefeller Capital Management L.P. | $128 139 | 5 295 | 0,01% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $118 846 | 4 911 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $91 428 | 3 778 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $76 303 | 3 153 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $76 000 | 3 164 | 0,00% | Actions |
| STRS OHIO | $70 180 | 2 900 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $64 153 | 2 651 | 0,00% | Actions |
| GAMMA Investing LLC | $51 159 | 2 114 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $39 107 | 1 616 | 0,00% | Actions |
| Allworth Financial LP | $29 912 | 1 236 | 0,00% | Actions |
| IFP Advisors, Inc | $28 508 | 1 178 | 0,00% | Actions |
| Essential Partners LLC | $19 868 | 821 | 0,00% | Actions |
| Kemnay Advisory Services Inc. | $17 303 | 715 | 0,00% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $15 415 | 637 | 0,00% | Actions |
| FIFTH THIRD BANCORP | $14 423 | 596 | 0,00% | Actions |
| Parkwood LLC | $12 221 | 505 000 | 0,00% | Actions |
| PNC Financial Services Group, Inc. | $11 059 | 457 | 0,00% | Actions |
| COMERICA BANK | $9 345 | 596 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $7 614 | 315 | 0,00% | Actions |
| Duquesne Family Office LLC | $7 202 | 297 600 | 0,00% | Actions |
| Fortitude Family Office, LLC | $6 365 | 263 | 0,00% | Actions |
| Sterling Capital Management LLC | $6 292 | 260 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $5 397 | 223 | 0,00% | Actions |
| Optiver Holding B.V. | $4 840 | 200 | 0,00% | Actions |
| Larson Financial Group LLC | $4 380 | 181 | 0,00% | Actions |
| Point72 Europe (London) LLP | $4 379 | 591 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $2 807 | 116 | 0,00% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $2 589 | 107 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $2 541 | 105 | 0,00% | Actions |
| True Wealth Design, LLC | $2 033 | 84 | 0,00% | Actions |
| Quarry LP | $1 621 | 67 | 0,00% | Actions |
| Dogwood Wealth Management LLC | $1 307 | 54 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $968 | 40 | 0,00% | Actions |
| Valued Wealth Advisors LLC | $944 | 39 | 0,00% | Actions |
| Smartleaf Asset Management LLC | $884 | 37 | 0,00% | Actions |
| SG Americas Securities, LLC | $704 | 29 083 | 0,00% | Actions |
| US BANCORP \DE\ | $702 | 29 | 0,00% | Actions |
| SJS Investment Consulting Inc. | $630 | 26 | 0,00% | Actions |
| Ameritas Advisory Services, LLC | $557 | 23 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $266 | 11 | 0,00% | Actions |
| Vestcor Inc | $102 | 4 234 | 0,00% | Actions |
| Covestor Ltd | $79 | 3 268 | 0,00% | Actions |
| Pacer Advisors, Inc. | $24 | 981 | 0,00% | Actions |
| Sunbelt Securities, Inc. | $16 | 1 | 0,00% | Actions |