OKUR — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $18 232 398 | 3 998 333 | 11,38% | Actions |
| BVF INC/IL | $14 755 148 | 3 235 778 | 9,21% | Actions |
| ACORN CAPITAL ADVISORS, LLC | $12 948 913 | 2 839 674 | 8,08% | Actions |
| StepStone Group LP | $11 014 934 | 2 660 612 | 6,88% | Actions |
| ADAR1 Capital Management, LLC | $10 208 399 | 2 238 684 | 6,37% | Actions |
| Vivo Capital, LLC | $8 790 358 | 1 927 710 | 5,49% | Actions |
| Vestal Point Capital, LP | $8 325 187 | 1 825 699 | 5,20% | Actions |
| BlackRock, Inc. | $6 839 294 | 1 499 845 | 4,27% | Actions |
| Trails Edge Capital Partners, LP | $6 559 359 | 1 438 456 | 4,10% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $6 552 898 | 1 437 039 | 4,09% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5 493 975 | 1 204 819 | 3,43% | Actions |
| CITADEL ADVISORS LLC | $5 412 934 | 1 187 047 | 3,38% | Actions |
| Sio Capital Management, LLC | $4 920 080 | 1 078 965 | 3,07% | Actions |
| Prosight Management, LP | $4 464 204 | 978 992 | 2,79% | Actions |
| Logos Global Management LP | $4 395 179 | 963 855 | 2,74% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $3 303 461 | 724 438 | 2,06% | Actions |
| NEA Management Company, LLC | $2 182 179 | 478 548 | 1,36% | Actions |
| STATE STREET CORP | $2 114 299 | 463 662 | 1,32% | Actions |
| Ensign Peak Advisors, Inc | $1 968 237 | 431 631 | 1,23% | Actions |
| VANGUARD GROUP INC | $1 817 120 | 626 593 | 1,13% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 635 845 | 358 738 | 1,02% | Actions |
| Sofinnova Investments, Inc. | $1 466 916 | 321 692 | 0,92% | Actions |
| Carlyle Group Inc. | $1 230 721 | 269 895 | 0,77% | Actions |
| Seven Fleet Capital Management LP | $1 098 791 | 240 963 | 0,69% | Actions |
| Affinity Asset Advisors, LLC | $1 098 791 | 240 963 | 0,69% | Actions |
| DV EQUITIES, LLC | $1 098 791 | 240 963 | 0,69% | Actions |
| NORTHERN TRUST CORP | $899 127 | 197 177 | 0,56% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $810 613 | 177 766 | 0,51% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $753 207 | 165 177 | 0,47% | Actions |
| MARSHALL WACE, LLP | $729 057 | 159 881 | 0,46% | Actions |
| Rosalind Advisors, Inc. | $684 000 | 150 000 | 0,43% | Actions |
| Stonepine Capital Management, LLC | $595 919 | 130 684 | 0,37% | Actions |
| KOTLER KEVIN | $573 304 | 197 691 | 0,36% | Actions |
| Longaeva Partners L.P. | $549 398 | 120 482 | 0,34% | Actions |
| TWO SIGMA INVESTMENTS, LP | $496 447 | 108 870 | 0,31% | Actions |
| BANK OF AMERICA CORP /DE/ | $484 819 | 106 320 | 0,30% | Actions |
| CANTOR FITZGERALD, L. P. | $456 064 | 100 014 | 0,28% | Actions |
| UBS Group AG | $454 194 | 99 604 | 0,28% | Actions |
| Rangeley Capital, LLC | $433 200 | 95 000 | 0,27% | Actions |
| Aisling Capital Management LP | $404 048 | 88 607 | 0,25% | Actions |
| Bank of New York Mellon Corp | $329 302 | 72 215 | 0,21% | Actions |
| Walleye Capital LLC | $324 230 | 71 103 | 0,20% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $312 453 | 68 563 | 0,20% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $290 198 | 63 640 | 0,18% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $229 336 | 50 293 | 0,14% | Actions |
| Shay Capital LLC | $228 000 | 50 000 | 0,14% | Actions |
| PRELUDE CAPITAL MANAGEMENT, LLC | $212 916 | 46 692 | 0,13% | Actions |
| Aldebaran Capital, LLC | $181 803 | 39 869 | 0,11% | Actions |
| WELLS FARGO & COMPANY/MN | $166 217 | 36 451 | 0,10% | Actions |
| Nuveen, LLC | $161 433 | 35 402 | 0,10% | Actions |
| BARCLAYS PLC | $144 643 | 31 720 | 0,09% | Actions |
| Verdad Advisers, LP | $130 690 | 28 660 | 0,08% | Actions |
| DEUTSCHE BANK AG\ | $116 572 | 25 564 | 0,07% | Actions |
| AMERICAN CENTURY COMPANIES INC | $105 231 | 23 077 | 0,07% | Actions |
| MORGAN STANLEY | $99 673 | 21 858 | 0,06% | Actions |
| RHUMBLINE ADVISERS | $95 736 | 20 996 | 0,06% | Actions |
| Jump Financial, LLC | $93 024 | 20 400 | 0,06% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $90 694 | 19 889 | 0,06% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $82 536 | 18 100 | 0,05% | Actions |
| XTX Topco Ltd | $77 383 | 16 970 | 0,05% | Actions |
| TWO SIGMA ADVISERS, LP | $77 163 | 26 608 | 0,05% | Actions |
| Invesco Ltd. | $62 181 | 13 636 | 0,04% | Actions |
| CITIGROUP INC | $55 586 | 12 190 | 0,03% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $55 035 | 12 069 | 0,03% | Actions |
| Y-Intercept (Hong Kong) Ltd | $51 473 | 11 288 | 0,03% | Actions |
| JPMORGAN CHASE & CO | $49 100 | 10 911 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $47 073 | 10 323 | 0,03% | Actions |
| Legal & General Group Plc | $11 651 | 2 555 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $10 848 | 2 379 | 0,01% | Actions |
| Russell Investments Group, Ltd. | $9 557 | 2 096 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $7 346 | 1 611 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $4 000 | 967 | 0,00% | Actions |
| Sterling Capital Management LLC | $2 408 | 528 | 0,00% | Actions |
| TRUST CO OF TOLEDO NA /OH/ | $620 | 136 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $410 | 90 | 0,00% | Actions |
| FMR LLC | $406 | 89 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $98 | 21 481 | 0,00% | Actions |
| T. Rowe Price Investment Management, Inc. | $70 | 15 335 | 0,00% | Actions |