TRDA — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $37 335 293 | 5 072 730 | 14,70% | Actions |
| 5AM Venture Management, LLC | $29 854 949 | 4 056 379 | 11,76% | Actions |
| MPM ASSET MANAGEMENT LLC | $25 410 160 | 4 381 062 | 10,01% | Actions |
| BlackRock, Inc. | $19 013 332 | 2 583 333 | 7,49% | Actions |
| VANGUARD GROUP INC | $16 781 689 | 1 632 460 | 6,61% | Actions |
| Merck & Co., Inc. | $12 804 692 | 1 739 768 | 5,04% | Actions |
| StepStone Group LP | $9 607 316 | 761 277 | 3,78% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $9 344 506 | 1 269 634 | 3,68% | Actions |
| MPM BIOIMPACT LLC | $9 222 470 | 1 253 053 | 3,63% | Actions |
| TCG Crossover Management, LLC | $7 803 293 | 1 060 230 | 3,07% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $7 024 524 | 954 419 | 2,77% | Actions |
| MILLENNIUM MANAGEMENT LLC | $5 622 738 | 763 959 | 2,21% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $5 281 368 | 717 430 | 2,08% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $5 148 591 | 699 537 | 2,03% | Actions |
| STATE STREET CORP | $4 391 543 | 596 677 | 1,73% | Actions |
| JPMORGAN CHASE & CO | $3 827 683 | 496 457 | 1,51% | Actions |
| CITADEL ADVISORS LLC | $2 902 217 | 394 323 | 1,14% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $2 769 577 | 376 136 | 1,09% | Actions |
| NORTHERN TRUST CORP | $2 281 173 | 309 942 | 0,90% | Actions |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2 233 458 | 303 459 | 0,88% | Actions |
| Nantahala Capital Management, LLC | $2 212 232 | 300 575 | 0,87% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 870 397 | 254 130 | 0,74% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 450 921 | 197 136 | 0,57% | Actions |
| Longaeva Partners L.P. | $1 436 944 | 195 237 | 0,57% | Actions |
| MORGAN STANLEY | $1 410 544 | 191 650 | 0,56% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 405 760 | 191 000 | 0,55% | Actions |
| Quantinno Capital Management LP | $1 389 855 | 188 839 | 0,55% | Actions |
| Lynx1 Capital Management LP | $1 314 540 | 178 606 | 0,52% | Actions |
| GOLDMAN SACHS GROUP INC | $1 305 247 | 177 343 | 0,51% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $1 233 875 | 167 646 | 0,49% | Actions |
| Woodline Partners LP | $1 071 616 | 145 600 | 0,42% | Actions |
| Trexquant Investment LP | $1 031 452 | 140 143 | 0,41% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $772 800 | 105 000 | 0,30% | Actions |
| Cubist Systematic Strategies, LLC | $711 521 | 122 676 | 0,28% | Actions |
| XTX Topco Ltd | $701 680 | 95 337 | 0,28% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $699 524 | 95 044 | 0,28% | Actions |
| Allspring Global Investments Holdings, LLC | $688 440 | 93 538 | 0,27% | Actions |
| ROYCE & ASSOCIATES LP | $610 159 | 82 902 | 0,24% | Actions |
| AMERICAN CENTURY COMPANIES INC | $586 599 | 79 701 | 0,23% | Actions |
| Bank of New York Mellon Corp | $581 955 | 79 070 | 0,23% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $533 747 | 72 520 | 0,21% | Actions |
| AMERIPRISE FINANCIAL INC | $518 107 | 70 395 | 0,20% | Actions |
| Qube Research & Technologies Ltd | $448 018 | 60 872 | 0,18% | Actions |
| CANTOR FITZGERALD, L. P. | $441 600 | 60 000 | 0,17% | Actions |
| BANK OF AMERICA CORP /DE/ | $426 343 | 57 927 | 0,17% | Actions |
| Nuveen, LLC | $417 879 | 56 777 | 0,16% | Actions |
| ALLIANCEBERNSTEIN L.P. | $399 297 | 31 640 | 0,16% | Actions |
| Susquehanna Portfolio Strategies, LLC | $398 272 | 54 113 | 0,16% | Actions |
| TD Asset Management Inc | $394 408 | 53 588 | 0,16% | Actions |
| ExodusPoint Capital Management, LP | $388 365 | 52 767 | 0,15% | Actions |
| Nan Fung Group Holdings Ltd | $361 244 | 49 082 | 0,14% | Actions |
| TWO SIGMA INVESTMENTS, LP | $341 519 | 46 402 | 0,13% | Actions |
| Invesco Ltd. | $326 372 | 44 344 | 0,13% | Actions |
| UBS Group AG | $305 911 | 41 564 | 0,12% | Actions |
| GREAT LAKES ADVISORS, LLC | $283 441 | 38 511 | 0,11% | Actions |
| MARTINGALE ASSET MANAGEMENT L P | $281 616 | 38 263 | 0,11% | Actions |
| HSBC HOLDINGS PLC | $278 266 | 36 470 | 0,11% | Actions |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $276 015 | 37 502 | 0,11% | Actions |
| RHUMBLINE ADVISERS | $270 421 | 36 743 | 0,11% | Actions |
| Y-Intercept (Hong Kong) Ltd | $255 296 | 34 687 | 0,10% | Actions |
| Brevan Howard Capital Management LP | $250 012 | 33 969 | 0,10% | Actions |
| Graham Capital Management, L.P. | $246 244 | 33 457 | 0,10% | Actions |
| D. E. Shaw & Co., Inc. | $238 442 | 32 397 | 0,09% | Actions |
| Odyssean, LLC | $230 405 | 31 305 | 0,09% | Actions |
| Corton Capital Inc. | $225 324 | 38 849 | 0,09% | Actions |
| IEQ CAPITAL, LLC | $218 437 | 29 679 | 0,09% | Actions |
| BARCLAYS PLC | $210 495 | 28 600 | 0,08% | Actions |
| Point72 Asset Management, L.P. | $209 760 | 28 500 | 0,08% | Actions |
| China Universal Asset Management Co., Ltd. | $204 446 | 27 778 | 0,08% | Actions |
| Verdad Advisers, LP | $202 400 | 27 500 | 0,08% | Actions |
| DEUTSCHE BANK AG\ | $195 452 | 26 556 | 0,08% | Actions |
| Voleon Capital Management LP | $186 385 | 25 324 | 0,07% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $184 000 | 25 000 | 0,07% | Actions |
| WELLS FARGO & COMPANY/MN | $183 279 | 24 902 | 0,07% | Actions |
| Jump Financial, LLC | $177 170 | 24 072 | 0,07% | Actions |
| Inscription Capital, LLC | $176 206 | 23 941 | 0,07% | Actions |
| Russell Investments Group, Ltd. | $172 591 | 23 450 | 0,07% | Actions |
| AlphaQuest LLC | $160 666 | 15 629 | 0,06% | Actions |
| Mariner, LLC | $159 779 | 21 707 | 0,06% | Actions |
| MERCER GLOBAL ADVISORS INC /ADV | $152 006 | 20 653 | 0,06% | Actions |
| MetLife Investment Management, LLC | $129 941 | 17 655 | 0,05% | Actions |
| ADAR1 Capital Management, LLC | $114 080 | 15 500 | 0,04% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $114 028 | 15 493 | 0,04% | Actions |
| CITIGROUP INC | $108 854 | 14 790 | 0,04% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $99 735 | 13 551 | 0,04% | Actions |
| Cerity Partners LLC | $99 442 | 13 511 | 0,04% | Actions |
| Quadrature Capital Ltd | $97 572 | 13 257 | 0,04% | Actions |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $88 364 | 12 769 | 0,03% | Actions |
| CWM, LLC | $85 665 | 6 788 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $69 707 | 9 471 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $65 335 | 8 877 | 0,03% | Actions |
| Vanguard Global Advisers, LLC | $64 856 | 8 812 | 0,03% | Actions |
| State of Wyoming | $36 903 | 5 014 | 0,01% | Actions |
| Arax Advisory Partners | $32 958 | 4 478 | 0,01% | Actions |
| Versant Capital Management, Inc | $26 702 | 4 205 | 0,01% | Actions |
| STRS OHIO | $23 552 | 3 200 | 0,01% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $21 874 | 2 972 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $21 462 | 2 916 | 0,01% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $19 784 | 2 688 | 0,01% | Actions |
| Legal & General Group Plc | $18 807 | 2 557 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $17 789 | 2 417 | 0,01% | Actions |
| FMR LLC | $15 962 | 2 169 | 0,01% | Actions |
| FEDERATED HERMES, INC. | $14 484 | 1 968 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $12 777 | 1 736 | 0,01% | Actions |
| PNC Financial Services Group, Inc. | $8 354 | 1 135 | 0,00% | Actions |
| Point72 (DIFC) Ltd | $7 876 | 1 358 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $6 000 | 882 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $5 976 | 812 | 0,00% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $5 490 | 435 | 0,00% | Actions |
| Allworth Financial LP | $4 762 | 647 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $4 724 | 642 | 0,00% | Actions |
| Essential Partners LLC | $4 394 | 597 | 0,00% | Actions |
| Sterling Capital Management LLC | $4 364 | 593 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $3 992 | 542 316 | 0,00% | Actions |
| GAMMA Investing LLC | $3 864 | 525 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $2 945 | 400 862 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2 937 | 399 | 0,00% | Actions |
| True Wealth Design, LLC | $2 260 | 307 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $2 009 | 273 | 0,00% | Actions |
| Optiver Holding B.V. | $1 722 | 234 | 0,00% | Actions |
| Private Wealth Management Group, LLC | $1 561 | 212 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $1 435 | 195 | 0,00% | Actions |
| MassMutual Private Wealth & Trust, FSB | $1 369 | 186 | 0,00% | Actions |
| IFP Advisors, Inc | $1 259 | 171 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $1 054 | 143 | 0,00% | Actions |
| Clearstead Advisors, LLC | $1 038 | 141 | 0,00% | Actions |
| Cornerstone Financial Management LLC | $670 | 91 | 0,00% | Actions |
| GSA CAPITAL PARTNERS LLP | $648 | 88 005 | 0,00% | Actions |
| ZIONS BANCORPORATION, NATIONAL ASSOCIATION /UT/ | $640 | 87 | 0,00% | Actions |
| SJS Investment Consulting Inc. | $523 | 71 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $339 | 46 | 0,00% | Actions |
| Wealth Enhancement Trust Services, Inc. | $316 | 43 | 0,00% | Actions |
| HARBOR CAPITAL ADVISORS, INC. | $245 | 33 351 | 0,00% | Actions |
| Quarry LP | $184 | 25 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $15 | 2 | 0,00% | Actions |