TRDA Entrada Therapeutics, Inc. - Common Stock
TRDA Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
TRDA Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
TRDA Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 5 35,7%
- Achat 7 50,0%
- Conserver 2 14,3%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
4 analystes · 2026-08-15Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-1.01 | $-1.07 | 0.06% |
| 31 mars 2026 | $-0.95 | $-1.06 | 0.11% |
| 31 décembre 2025 | $-0.94 | $-1.17 | 0.23% |
| 30 septembre 2025 | $-1.06 | $-0.96 | -0.10% |
| 30 juin 2025 | $-1.04 | $-0.86 | -0.18% |
| 31 mars 2025 | $-0.42 | $-0.80 | 0.38% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| TRDA | $394M | -3.0 | -87.9% | -565.5% | -41.9% | — |
| RCEL | $105M | -2.0 | 11.5% | -67.8% | 328.9% | 82.1% |
| RNAC | $188M | -1.4 | -92.8% | -4658.6% | 202.4% | — |
| AVXL | $771M | -16.5 | -36.1% | -991.4% | -47.7% | — |
| VNDA | $521M | -2.4 | 8.7% | -102.0% | -54.2% | — |
| CAMP | $318M | -2.3 | 436.5% | -2298.5% | -183.4% | — |
| MYGN | $575M | -1.6 | -1.6% | -44.4% | -96.8% | 69.9% |
| ANIK | $133M | -12.6 | -5.9% | -9.6% | -7.5% | 56.6% |
| ELDN | $114M | -2.9 | — | — | -69.4% | — |
| ALXO | $61M | -0.6 | — | — | -225.0% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 13
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $25M | $211M | $129M | |
| R&D Expense | $142M | $125M | $100M | |
| SG&A Expense | $41M | $38M | $32M | |
| Operating Expenses | $183M | $164M | $132M | |
| Operating Income | $-158M | $47M | $-3M | |
| Other Non-op | $15M | $19M | $15M | |
| Income Tax | $924.0K | $859.0K | $19M | |
| Net Income | $-144M | $66M | $-7M | |
| EPS (Basic) | $-3.47 | $1.76 | $-0.20 | |
| EPS (Diluted) | $-3.47 | $1.68 | $-0.20 | |
| Shares (Basic) | 41,371,486 | 37,306,363 | 33,050,319 | |
| Shares (Diluted) | 41,371,486 | 39,003,169 | 33,050,319 | |
| EBITDA | $-158M | $47M | $-3M |
Bilan 20
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $90M | $101M | $68M | |
| Prepaid Expense | $9M | $16M | $12M | |
| Current Assets | $306M | $440M | $370M | |
| PP&E (Net) | $7M | $11M | $11M | |
| PP&E (Gross) | $17M | $20M | $17M | |
| Accum. Depreciation | $10M | $9M | $6M | |
| Other Non-current Assets | $70.0K | $284.0K | $3M | |
| Total Assets | $377M | $526M | $469M | |
| Accounts Payable | $2M | $4M | $3M | |
| Accrued Liabilities | $18M | $13M | $11M | |
| Current Liabilities | $24M | $39M | $159M | |
| Capital Leases | $47M | $52M | $60M | |
| Total Liabilities | $71M | $98M | $227M | |
| Common Stock | $4.0K | $4.0K | $3.0K | |
| Paid-in Capital | $579M | $558M | $437M | |
| Retained Earnings | $-273M | $-129M | $-195M | |
| AOCI | $652.0K | $-43.0K | $195.0K | |
| Stockholders' Equity | $306M | $429M | $242M | |
| Liabilities + Equity | $377M | $526M | $469M | |
| Shares Outstanding | 38,284,221 | 37,574,538 | 33,437,296 |
Flux de trésorerie 9
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $20M | $18M | $13M | |
| Deferred Tax | $0 | $0 | $0 | |
| Operating Cash Flow | $-129M | $-42M | $140M | |
| CapEx | $1M | $3M | $6M | |
| Investing Cash Flow | $117M | $-28M | $-138M | |
| Financing Cash Flow | $887.0K | $103M | $21M | |
| Net Change in Cash | $-11M | $34M | $22M | |
| Taxes Paid | $2M | $5M | $15M | |
| Free Cash Flow | $-130M | $-45M | $134M |
Rentabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -621.1% | 22.3% | -2.5% | |
| Net Margin | -565.5% | 31.1% | -5.2% | |
| EBITDA Margin | -621.1% | 22.3% | -2.5% | |
| ROA | -31.8% | 13.2% | -1.8% | |
| ROE | -41.9% | 15.4% | -2.7% |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 12.5 | 11.1 | 2.3 | |
| Quick Ratio | 3.7 | 2.6 | 0.4 |
Efficacité 1
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.4 | 0.4 |
Taux de croissance 1
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | -87.9% | 63.4% | · |
Valorisation (TTM) 10
| Métrique | Tendance | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $25M | $211M | $129M | |
| Net Income TTM | $-144M | $66M | $-7M | |
| Market Cap | $394M | $650M | $505M | |
| P/E | -3.0 | 10.3 | -75.5 | |
| P/S | 15.5 | 3.1 | 3.9 | |
| P/B | 1.3 | 1.5 | 2.1 | |
| P / Tangible Book | 1.3 | 1.5 | 2.1 | |
| P / Cash Flow | -3.1 | -15.6 | 3.6 | |
| P / FCF | -3.0 | -14.5 | 3.8 | |
| Earnings Yield | -33.8% | 9.7% | -1.3% |
Compte de résultat 13
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $898.0K | $875.0K | $1M | $2M | $2M | $21M | $37M | $20M | $95M | $59M | $42M | $44M | $18M | $25M | · | $0 | |
| R&D Expense | $35M | $33M | $34M | $38M | $38M | $32M | $33M | $31M | $32M | $29M | $28M | $22M | $26M | $23M | $16M | $19M | |
| SG&A Expense | $10M | $10M | $10M | $10M | $11M | $10M | $10M | $10M | $9M | $9M | $9M | $8M | $8M | $8M | $10M | $7M | |
| Operating Expenses | $46M | $43M | $44M | $49M | $49M | $42M | $43M | $41M | $41M | $38M | $37M | $30M | $34M | $31M | $26M | $26M | |
| Operating Income | $-45M | $-42M | $-42M | $-47M | $-47M | $-22M | $-6M | $-22M | $53M | $21M | $5M | $14M | $-16M | $-6M | $-26M | $-26M | |
| Other Non-op | $2M | $3M | $3M | $4M | $4M | $4M | $5M | $6M | $4M | $4M | $4M | $4M | $4M | $3M | $950.0K | $799.0K | |
| Income Tax | $35.0K | $38.0K | $92.0K | $654.0K | $178.0K | $0 | $-2M | $-2M | $3M | $2M | $19M | $-17M | $14M | $4M | $0 | $0 | |
| Net Income | $-43M | $-40M | $-39M | $-44M | $-43M | $-17M | $1M | $-14M | $55M | $23M | $-10M | $35M | $-26M | $-7M | $-25M | $-25M | |
| EPS (Basic) | $-1.01 | $-0.95 | $-0.95 | $-1.06 | $-1.04 | $-0.42 | $-0.20 | $-0.35 | $1.61 | $0.70 | $-0.28 | $1.07 | $-0.78 | $-0.21 | $-0.79 | $-0.80 | |
| EPS (Diluted) | $-1.01 | $-0.95 | $-0.95 | $-1.06 | $-1.04 | $-0.42 | $-0.20 | $-0.35 | $1.55 | $0.68 | $-0.23 | $1.02 | $-0.78 | $-0.21 | $-0.79 | $-0.80 | |
| Shares (Basic) | 42,221,665 | 41,836,275 | -82,503,565 | 41,462,567 | 41,338,752 | 41,073,732 | -71,000,860 | 40,629,602 | 34,180,549 | 33,497,072 | -65,768,587 | 33,281,287 | 33,163,320 | 32,374,299 | -62,526,962 | 31,298,052 | |
| Shares (Diluted) | 42,221,665 | 41,836,275 | -82,503,565 | 41,462,567 | 41,338,752 | 41,073,732 | -71,924,387 | 40,629,602 | 35,507,029 | 34,790,925 | -67,262,751 | 34,775,451 | 33,163,320 | 32,374,299 | -62,526,962 | 31,298,052 | |
| EBITDA | $-45M | $-42M | · | $-47M | $-47M | $-22M | · | $-22M | $53M | $21M | · | $14M | $-16M | · | · | $-26M |
Bilan 21
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $99M | $76M | $90M | $93M | $72M | $68M | $101M | $78M | $185M | $68M | $68M | $52M | $80M | $228M | $45M | $53M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $162M | |
| Prepaid Expense | $9M | $11M | $9M | $10M | $14M | $19M | $16M | $13M | $12M | $9M | $12M | $24M | $10M | $16M | $21M | $19M | |
| Current Assets | $233M | $267M | $306M | $338M | $369M | $403M | $440M | $465M | $490M | $414M | $370M | $383M | $390M | $434M | $210M | $235M | |
| PP&E (Net) | $6M | $7M | $7M | $8M | $10M | $11M | $11M | $11M | $11M | $11M | $11M | $11M | $11M | $9M | $8M | $7M | |
| PP&E (Gross) | $16M | $17M | $17M | $19M | $21M | $21M | $20M | $19M | $19M | $18M | $17M | $16M | $15M | $13M | $11M | $10M | |
| Accum. Depreciation | $11M | $10M | $10M | $10M | $11M | $10M | $9M | $8M | $8M | $7M | $6M | $5M | $4M | $4M | $3M | $3M | |
| Other Non-current Assets | $118.0K | $90.0K | $70.0K | $163.0K | $199.0K | $239.0K | $284.0K | $746.0K | $747.0K | $3M | $3M | $3M | $538.0K | $14M | $5M | $954.0K | |
| Total Assets | $299M | $336M | $377M | $413M | $449M | $486M | $526M | $555M | $582M | $511M | $469M | $485M | $494M | $476M | $252M | $274M | |
| Accounts Payable | $4M | $3M | $2M | $3M | $2M | $2M | $4M | $1M | $2M | $3M | $3M | $752.0K | $2M | $6M | $6M | $1M | |
| Accrued Liabilities | $13M | $12M | $18M | $16M | $12M | $8M | $13M | $13M | $11M | $9M | $11M | $10M | $7M | $12M | $8M | $12M | |
| Current Liabilities | $21M | $19M | $24M | $24M | $20M | $18M | $39M | $71M | $86M | $174M | $159M | $165M | $126M | $148M | $22M | $22M | |
| Capital Leases | $44M | $45M | $47M | $48M | $49M | $50M | $52M | $54M | $56M | $58M | $60M | $62M | $66M | $9M | $18M | $20M | |
| Total Liabilities | $65M | $65M | $71M | $72M | $69M | $69M | $98M | $132M | $152M | $241M | $227M | $238M | $287M | $246M | $40M | $41M | |
| Common Stock | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $589M | $583M | $579M | $574M | $569M | $564M | $558M | $552M | $547M | $441M | $437M | $433M | $429M | $425M | $403M | $400M | |
| Retained Earnings | $-356M | $-313M | $-273M | $-234M | $-190M | $-147M | $-129M | $-130M | $-116M | $-171M | $-195M | $-185M | $-221M | $-195M | $-188M | $-164M | |
| AOCI | $66.0K | $246.0K | $652.0K | $621.0K | $400.0K | $437.0K | $-43.0K | $972.0K | $-329.0K | $-246.0K | $195.0K | $-496.0K | $-1M | $-642.0K | $-2M | $-3M | |
| Stockholders' Equity | $233M | $271M | $306M | $341M | $380M | $417M | $429M | $422M | $430M | $269M | $242M | $247M | $207M | $230M | $213M | $233M | |
| Liabilities + Equity | $299M | $336M | $377M | $413M | $449M | $486M | $526M | $555M | $582M | $511M | $469M | $485M | $494M | $476M | $252M | $274M | |
| Shares Outstanding | 38,936,669 | 38,820,616 | 38,284,221 | 38,219,232 | 38,033,970 | 37,942,283 | 37,574,538 | 37,400,499 | 37,172,496 | 33,604,053 | 33,437,296 | 33,340,216 | 33,205,693 | 33,133,736 | 31,394,767 | 31,325,373 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $5M | $5M | $4M | $5M | $5M | $5M | $5M | $5M | $5M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | |
| Operating Cash Flow | $-32M | $-42M | $-32M | $-28M | $-29M | $-39M | $-32M | $-24M | $40M | $-26M | $-4M | $-24M | $-35M | $203M | $-27M | $-27M | |
| CapEx | $11.0K | $44.0K | $-207.0K | $-171.0K | $275.0K | $1M | $635.0K | $639.0K | $1M | $838.0K | $976.0K | $1M | $2M | $2M | $708.0K | $810.0K | |
| Investing Cash Flow | $55M | $27M | $29M | $49M | $34M | $5M | $53M | $-83M | $-24M | $26M | $19M | $-4M | $-113M | $-40M | $19M | $-10M | |
| Stock Issued | · | · | · | $0 | · | · | · | $-392.0K | $100M | $0 | · | $0 | $0 | $19M | · | $0 | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $0 | · | · | · | · | · | · | |
| Financing Cash Flow | $350.0K | $100.0K | $192.0K | $8.0K | $337.0K | $350.0K | $1M | $-11.0K | $101M | $206.0K | $690.0K | $368.0K | $443.0K | $20M | $358.0K | $60.0K | |
| Net Change in Cash | $23M | $-15M | $-3M | $21M | $5M | $-33M | $23M | $-107M | $117M | $834.0K | $16M | $-28M | $-148M | $182M | $-8M | $-38M | |
| Free Cash Flow | · | $-42M | · | · | · | $-40M | · | · | · | $-26M | · | · | · | · | · | · |
Rentabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -5007.0% | -4834.6% | · | -2915.2% | -2402.5% | -106.0% | · | -110.7% | 56.4% | 35.7% | · | 32.0% | -89.7% | · | · | · | |
| Net Margin | -4762.0% | -4539.1% | · | -2734.4% | -2210.4% | -84.4% | · | -71.7% | 58.1% | 39.7% | · | 81.1% | -142.7% | · | · | · | |
| EBITDA Margin | -5007.0% | -4834.6% | · | -2915.2% | -2402.5% | -106.0% | · | -110.7% | 56.4% | 35.7% | · | 32.0% | -89.7% | · | · | · | |
| ROA | -11.4% | -9.7% | · | -9.1% | -8.4% | -3.5% | · | -2.7% | 10.2% | 4.8% | · | 9.3% | -6.6% | · | · | -12.4% | |
| ROE | -14.0% | -11.5% | · | -11.6% | -10.7% | -5.1% | · | -4.2% | 17.3% | 9.4% | · | 14.8% | -11.2% | · | · | -31.3% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 10.9 | 13.9 | · | 14.1 | 18.6 | 21.9 | · | 6.6 | 5.7 | 2.4 | · | 2.3 | 3.1 | · | · | 10.9 | |
| Quick Ratio | 4.6 | 4.0 | · | 3.9 | 3.7 | 3.7 | · | 1.1 | 2.2 | 0.4 | · | 0.3 | 0.6 | · | · | 10.0 |
Efficacité 1
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.2 | 0.1 | · | 0.1 | 0.0 | · | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $5M | $25M | · | $44M | $137M | $194M | · | $217M | $216M | $146M | · | $87M | $43M | $25M | · | · | |
| Net Income TTM | $-170M | $-144M | · | $-119M | $-19M | $47M | · | $100M | $88M | $26M | · | $-22M | $-81M | $-77M | · | $-84M | |
| Market Cap | $287M | $490M | · | $222M | $256M | $343M | · | $598M | $530M | $476M | · | $527M | $503M | · | · | $494M | |
| P/E | -1.8 | -3.6 | · | -2.0 | -25.8 | 6.2 | · | 5.5 | 5.8 | 20.0 | · | -20.5 | -6.0 | -5.9 | · | -1.3 | |
| P/S | 53.7 | 19.6 | · | 5.1 | 1.9 | 1.8 | · | 2.8 | 2.5 | 3.3 | · | 6.0 | 11.6 | · | · | · | |
| P/B | 1.2 | 1.8 | · | 0.7 | 0.7 | 0.8 | · | 1.4 | 1.2 | 1.8 | · | 2.1 | 2.4 | · | · | 2.1 | |
| P / Tangible Book | 1.2 | 1.8 | · | 0.7 | 0.7 | 0.8 | · | 1.4 | 1.2 | 1.8 | · | 2.1 | 2.4 | 2.1 | · | 2.1 | |
| P / Cash Flow | · | -11.8 | · | · | · | -8.9 | · | · | · | -18.7 | · | · | · | · | · | · | |
| P / FCF | · | -11.7 | · | · | · | -8.7 | · | · | · | -18.1 | · | · | · | · | · | · | |
| Earnings Yield | -55.2% | -27.5% | · | -49.5% | -3.9% | 16.2% | · | 18.1% | 17.3% | 5.0% | · | -4.9% | -16.7% | -16.8% | · | -76.2% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $25M | $211M | $129M | — | — |
| Marge d'exploitation % | -621.1% | 22.3% | -2.5% | — | — |
| Résultat net | $-144M | $66M | $-7M | $-95M | $-51M |
| BPA dilué | $-3.47 | $1.68 | $-0.20 | $-3.02 | $-8.16 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 12.5 | 11.1 | 2.3 | — | 44.5 |
| Ratio de liquidité réduite | 3.7 | 2.6 | 0.4 | — | 43.3 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-130M | $-45M | $134M | — | $-55M |
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Détenteurs institutionnels (13F) 137 déclarants · $224.4M total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 34 (+12 vs T. préc.) | 16 (+4 vs T. préc.) | 47 (+2 vs T. préc.) | 30 (0 vs T. préc.) | +2.9M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $37 335 293 | 5 072 730 | 16,63% | Actions |
| 5AM Venture Management, LLC | $29 854 949 | 4 056 379 | 13,30% | Actions |
| MPM ASSET MANAGEMENT LLC | $25 410 160 | 4 381 062 | 11,32% | Actions |
| VANGUARD GROUP INC | $15 056 160 | 1 464 607 | 6,71% | Actions |
| Merck & Co., Inc. | $12 804 692 | 1 739 768 | 5,71% | Actions |
| StepStone Group LP | $9 607 316 | 761 277 | 4,28% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $9 344 506 | 1 269 634 | 4,16% | Actions |
| MPM BIOIMPACT LLC | $9 222 470 | 1 253 053 | 4,11% | Actions |
| TCG Crossover Management, LLC | $7 803 293 | 1 060 230 | 3,48% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $7 024 524 | 954 419 | 3,13% | Actions |
| MILLENNIUM MANAGEMENT LLC | $5 622 738 | 763 959 | 2,51% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $5 114 103 | 694 851 | 2,28% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $4 548 555 | 617 863 | 2,03% | Actions |
| STATE STREET CORP | $4 391 543 | 596 677 | 1,96% | Actions |
| JPMORGAN CHASE & CO | $3 170 992 | 411 283 | 1,41% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $2 523 148 | 342 819 | 1,12% | Actions |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2 233 458 | 303 459 | 1,00% | Actions |
| Nantahala Capital Management, LLC | $2 212 232 | 300 575 | 0,99% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 870 397 | 254 130 | 0,83% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 450 921 | 197 136 | 0,65% | Actions |
| Longaeva Partners L.P. | $1 436 944 | 195 237 | 0,64% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 405 760 | 191 000 | 0,63% | Actions |
| Quantinno Capital Management LP | $1 389 855 | 188 839 | 0,62% | Actions |
| Lynx1 Capital Management LP | $1 314 540 | 178 606 | 0,59% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $1 233 875 | 167 646 | 0,55% | Actions |
| BlackRock, Inc. | $1 216 689 | 165 311 | 0,54% | Actions |
| Woodline Partners LP | $1 071 616 | 145 600 | 0,48% | Actions |
| Trexquant Investment LP | $1 031 452 | 140 143 | 0,46% | Actions |
| GOLDMAN SACHS GROUP INC | $1 022 262 | 138 894 | 0,46% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $772 800 | 105 000 | 0,34% | Actions |
| Cubist Systematic Strategies, LLC | $711 521 | 122 676 | 0,32% | Actions |
| XTX Topco Ltd | $701 680 | 95 337 | 0,31% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $699 524 | 95 044 | 0,31% | Actions |
| Allspring Global Investments Holdings, LLC | $688 440 | 93 538 | 0,31% | Actions |
| ROYCE & ASSOCIATES LP | $610 159 | 82 902 | 0,27% | Actions |
| AMERICAN CENTURY COMPANIES INC | $586 599 | 79 701 | 0,26% | Actions |
| CITADEL ADVISORS LLC | $551 058 | 74 872 | 0,25% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $533 747 | 72 520 | 0,24% | Actions |
| AMERIPRISE FINANCIAL INC | $518 107 | 70 395 | 0,23% | Actions |
| Qube Research & Technologies Ltd | $448 018 | 60 872 | 0,20% | Actions |
| CANTOR FITZGERALD, L. P. | $441 600 | 60 000 | 0,20% | Actions |
| ALLIANCEBERNSTEIN L.P. | $399 297 | 31 640 | 0,18% | Actions |
| Susquehanna Portfolio Strategies, LLC | $398 272 | 54 113 | 0,18% | Actions |
| TD Asset Management Inc | $394 408 | 53 588 | 0,18% | Actions |
| ExodusPoint Capital Management, LP | $388 365 | 52 767 | 0,17% | Actions |
| Nan Fung Group Holdings Ltd | $361 244 | 49 082 | 0,16% | Actions |
| TWO SIGMA INVESTMENTS, LP | $341 519 | 46 402 | 0,15% | Actions |
| BANK OF AMERICA CORP /DE/ | $314 265 | 42 699 | 0,14% | Actions |
| MARTINGALE ASSET MANAGEMENT L P | $281 616 | 38 263 | 0,13% | Actions |
| HSBC HOLDINGS PLC | $278 266 | 36 470 | 0,12% | Actions |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $276 015 | 37 502 | 0,12% | Actions |
| RHUMBLINE ADVISERS | $270 421 | 36 743 | 0,12% | Actions |
| Y-Intercept (Hong Kong) Ltd | $255 296 | 34 687 | 0,11% | Actions |
| Brevan Howard Capital Management LP | $250 012 | 33 969 | 0,11% | Actions |
| Graham Capital Management, L.P. | $246 244 | 33 457 | 0,11% | Actions |
| D. E. Shaw & Co., Inc. | $238 442 | 32 397 | 0,11% | Actions |
| Odyssean, LLC | $230 405 | 31 305 | 0,10% | Actions |
| Corton Capital Inc. | $225 324 | 38 849 | 0,10% | Actions |
| IEQ CAPITAL, LLC | $218 437 | 29 679 | 0,10% | Actions |
| Point72 Asset Management, L.P. | $209 760 | 28 500 | 0,09% | Actions |
| China Universal Asset Management Co., Ltd. | $204 446 | 27 778 | 0,09% | Actions |
| BARCLAYS PLC | $204 298 | 27 758 | 0,09% | Actions |
| Verdad Advisers, LP | $202 400 | 27 500 | 0,09% | Actions |
| Bank of New York Mellon Corp | $198 661 | 26 992 | 0,09% | Actions |
| DEUTSCHE BANK AG\ | $195 452 | 26 556 | 0,09% | Actions |
| Voleon Capital Management LP | $186 385 | 25 324 | 0,08% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $184 000 | 25 000 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $181 395 | 24 646 | 0,08% | Actions |
| Inscription Capital, LLC | $176 206 | 23 941 | 0,08% | Actions |
| AlphaQuest LLC | $160 666 | 15 629 | 0,07% | Actions |
| Mariner, LLC | $159 779 | 21 707 | 0,07% | Actions |
| MERCER GLOBAL ADVISORS INC /ADV | $152 006 | 20 653 | 0,07% | Actions |
| MetLife Investment Management, LLC | $129 941 | 17 655 | 0,06% | Actions |
| ADAR1 Capital Management, LLC | $114 080 | 15 500 | 0,05% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $114 028 | 15 493 | 0,05% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $99 735 | 13 551 | 0,04% | Actions |
| Quadrature Capital Ltd | $97 572 | 13 257 | 0,04% | Actions |
| CITIGROUP INC | $96 357 | 13 092 | 0,04% | Actions |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $88 364 | 12 769 | 0,04% | Actions |
| CWM, LLC | $85 665 | 6 788 | 0,04% | Actions |
| Invesco Ltd. | $85 656 | 11 638 | 0,04% | Actions |
| Cerity Partners LLC | $72 091 | 9 795 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $69 707 | 9 471 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $65 335 | 8 877 | 0,03% | Actions |
| Vanguard Global Advisers, LLC | $64 856 | 8 812 | 0,03% | Actions |
| MORGAN STANLEY | $39 494 | 5 366 | 0,02% | Actions |
| State of Wyoming | $36 903 | 5 014 | 0,02% | Actions |
| NORTHERN TRUST CORP | $34 489 | 4 686 | 0,02% | Actions |
| Arax Advisory Partners | $32 958 | 4 478 | 0,01% | Actions |
| Versant Capital Management, Inc | $31 067 | 4 221 | 0,01% | Actions |
| Nuveen Asset Management, LLC | $26 454 | 1 530 | 0,01% | Actions |
| STRS OHIO | $23 552 | 3 200 | 0,01% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $21 874 | 2 972 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $21 462 | 2 916 | 0,01% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $19 784 | 2 688 | 0,01% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $19 435 | 1 540 | 0,01% | Actions |
| Legal & General Group Plc | $18 807 | 2 557 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $17 789 | 2 417 | 0,01% | Actions |
| FMR LLC | $15 692 | 2 132 | 0,01% | Actions |
| FEDERATED HERMES, INC. | $14 484 | 1 968 | 0,01% | Actions |
Initiés de la société 14 initiés · 5 dirigeants · 9 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Dipal Doshi | President and CEO | 1 septembre 2022 A | 221 835 | 0 | 0 | $0 |
| Kory James Wentworth | Chief Financial Officer | 1 septembre 2022 A | 16 489 | 0 | 0 | $0 |
| Nathan J Dowden | Chief Operating Officer | 1 septembre 2022 A | 70 525 | 0 | 0 | $0 |
| Natarajan Sethuraman | Chief Scientific Officer | 1 septembre 2022 A | 162 144 | 0 | 0 | $0 |
| Nerissa Kreher | Chief Medical Officer | 1 septembre 2022 A | 20 716 | 0 | 0 | $0 |
| Maha Radhakrishnan | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Gina Chapman | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Bernhardt G Zeiher | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Mary Thistle | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| Peter S Kim | Administrateur | 10 juin 2026 A | — | 0 | 0 | $0 |
| John F Crowley | Administrateur | 8 juin 2023 A | 5 000 | 0 | 0 | $0 |
| Carole Nuechterlein | Administrateur | 2 juin 2022 A | — | 0 | 0 | $0 |
| Todd Foley | Administrateur | 2 juin 2022 A | 4 425 784 | 0 | 0 | $0 |
| Kush Parmar | — | 10 août 2026 S | 2 691 337 | 0 | 5 | $-1 885 964 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 4 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| 5AM Ventures V, L.P., 5AM Partners V, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Andrew J. Schwab, Kush Parmar, Scott M. Rocklage | 18 novembre 2025 | 10,80% | Amendement | — | SEC |
| Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Felix J. Baker, Julian C. Baker ×2 dépôts | 26 juin 2024 | — | Dépôt initial | Investissement passif | SEC |
| MPM BioVentures 2014, L.P., MPM BioVentures 2014 (B), L.P., MPM Asset Management Investors BV2014 LLC, MPM BioVentures 2018, L.P., MPM BioVentures 2018 (B), L.P., MPM Asset Management Investors BV2018 LLC, MPM BioVentures 2014 GP LLC, MPM BioVentures 2014 LLC, MPM BioVentures 2018 GP LLC, MPM BioVentures 2018 LLC, Ansbert Gadicke, Luke Evnin, Todd Foley, Edward Hurwitz | 12 novembre 2021 | — | Dépôt initial | Investissement passif | SEC |
| 5AM Partners V, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Andrew J. Schwab, Dr. Kush Parmar, Dr. Scott M. Rocklage | 12 novembre 2021 | — | Dépôt initial | Investissement passif | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 34 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| HAPS · Harbor ETF Trust | 0,16% | 18 286 NS | 30 avril 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 33 055 NS | 31 mai 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 69 412 NS | 31 mai 2026 | N-PORT |
| BIB · ProShares Trust | 0,01% | 1 416 NS | 31 mai 2026 | N-PORT |
| RSSL · Global X Funds | 0,01% | 12 375 NS | 30 avril 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,01% | 100 802 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 1 340 NS | 31 mai 2026 | N-PORT |
| DFSV · Dimensional ETF Trust | 0,00% | 27 316 NS | 30 avril 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,00% | 113 479 NS | 31 mai 2026 | N-PORT |
| UWM · ProShares Trust | 0,00% | 1 047 NS | 31 mai 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 800 NS | 30 avril 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 1 057 NS | 31 mai 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 742 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 27 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 7 570 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 888 NS | 31 mai 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 6 979 NS | 31 mai 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 17 261 NS | 31 mai 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 1 647 NS | 30 avril 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 2 069 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWV · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| IWV · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWN · iShares Trust | — | — | 17 août 2026 | Quotidien |
| IWM · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IBB · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWC · iShares Trust | — | — | 18 août 2026 | Quotidien |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | 13 juillet 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | — | — | 20 juillet 2026 | Quotidien |
| IBRN · iShares Trust | — | — | 6 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | 20 juillet 2026 | Quotidien |