BIOA — Pemilik institusional (13F)
Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.
| Institusi | Nilai | Saham | % dari 13F yang dilacak | Tipe |
|---|---|---|---|---|
| a16z Capital Management, L.L.C. | $79.244.997 | 3.233.170 | 8,37% | Saham |
| BlackRock, Inc. | $69.830.877 | 2.849.077 | 7,38% | Saham |
| Cormorant Asset Management, LP | $58.593.729 | 2.390.605 | 6,19% | Saham |
| Sofinnova Investments, Inc. | $56.220.744 | 2.293.788 | 5,94% | Saham |
| Octagon Capital Advisors LP | $42.843.480 | 1.748.000 | 4,53% | Saham |
| RA CAPITAL MANAGEMENT, L.P. | $40.972.092 | 1.671.648 | 4,33% | Saham |
| MPM BIOIMPACT LLC | $40.874.371 | 1.667.661 | 4,32% | Saham |
| VANGUARD CAPITAL MANAGEMENT LLC | $37.848.685 | 1.544.214 | 4,00% | Saham |
| JANUS HENDERSON GROUP PLC | $36.597.368 | 2.094.270 | 3,87% | Saham |
| Polar Capital Holdings Plc | $26.283.151 | 1.072.344 | 2,78% | Saham |
| BRAIDWELL LP | $25.321.992 | 1.033.129 | 2,67% | Saham |
| STATE STREET CORP | $25.036.083 | 1.021.464 | 2,64% | Saham |
| GEODE CAPITAL MANAGEMENT, LLC | $24.619.235 | 1.004.264 | 2,60% | Saham |
| Sands Capital Alternatives, LLC | $19.273.512 | 786.353 | 2,04% | Saham |
| VANGUARD GROUP INC | $18.717.407 | 1.414.770 | 1,98% | Saham |
| ORBIMED ADVISORS LLC | $18.435.270 | 752.153 | 1,95% | Saham |
| D. E. Shaw & Co., Inc. | $18.205.072 | 742.761 | 1,92% | Saham |
| Balyasny Asset Management L.P. | $17.227.050 | 702.858 | 1,82% | Saham |
| Pivotal bioVenture Partners Investment Advisor LLC | $16.014.197 | 653.374 | 1,69% | Saham |
| COSMIC MANAGEMENT, LLC | $12.299.927 | 501.833 | 1,30% | Saham |
| STEMPOINT CAPITAL LP | $11.376.831 | 464.171 | 1,20% | Saham |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $10.053.144 | 410.165 | 1,06% | Saham |
| DIMENSIONAL FUND ADVISORS LP | $9.661.958 | 394.138 | 1,02% | Saham |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $9.242.353 | 377.085 | 0,98% | Saham |
| Walleye Capital LLC | $8.686.221 | 354.395 | 0,92% | Saham |
| Nuveen, LLC | $8.557.471 | 349.142 | 0,90% | Saham |
| NORTHERN TRUST CORP | $8.410.999 | 343.166 | 0,89% | Saham |
| Integral Health Asset Management, LLC | $7.353.000 | 300.000 | 0,78% | Saham |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $7.353.000 | 300.000 | 0,78% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $7.267.215 | 296.500 | 0,77% | Opsi beli |
| MORGAN STANLEY | $6.921.282 | 282.386 | 0,73% | Saham |
| FRANKLIN RESOURCES INC | $6.911.011 | 281.967 | 0,73% | Saham |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $6.700.323 | 273.371 | 0,71% | Saham |
| Comprehensive Financial Management LLC | $6.662.847 | 271.842 | 0,70% | Saham |
| GOLDMAN SACHS GROUP INC | $6.636.548 | 270.769 | 0,70% | Saham |
| BANK OF AMERICA CORP /DE/ | $6.320.026 | 257.855 | 0,67% | Saham |
| Squadron Capital Management LLC | $6.127.500 | 250.000 | 0,65% | Opsi beli |
| JPMORGAN CHASE & CO | $5.837.776 | 233.979 | 0,62% | Saham |
| MILLENNIUM MANAGEMENT LLC | $5.456.441 | 222.621 | 0,58% | Saham |
| VANGUARD FIDUCIARY TRUST CO | $5.382.396 | 219.600 | 0,57% | Saham |
| SPHERA FUNDS MANAGEMENT LTD. | $5.237.076 | 213.671 | 0,55% | Saham |
| DIADEMA PARTNERS LP | $4.904.451 | 200.100 | 0,52% | Opsi beli |
| Ikarian Capital, LLC | $4.901.999 | 200.000 | 0,52% | Saham |
| FMR LLC | $4.499.129 | 183.563 | 0,48% | Saham |
| Yiheng Capital Management, L.P. | $4.179.739 | 170.532 | 0,44% | Saham |
| RENAISSANCE TECHNOLOGIES LLC | $4.061.307 | 165.700 | 0,43% | Saham |
| Squadron Capital Management LLC | $3.799.050 | 155.000 | 0,40% | Saham |
| DIADEMA PARTNERS LP | $3.586.646 | 146.334 | 0,38% | Saham |
| Ensign Peak Advisors, Inc | $3.473.018 | 141.698 | 0,37% | Saham |
| Invesco Ltd. | $3.123.064 | 127.420 | 0,33% | Saham |
| Bank of New York Mellon Corp | $2.630.698 | 107.332 | 0,28% | Saham |
| UBS Group AG | $2.522.716 | 102.926 | 0,27% | Saham |
| NEXTBio Capital Management LP | $2.468.941 | 100.732 | 0,26% | Saham |
| Burkehill Global Management, LP | $2.451.000 | 100.000 | 0,26% | Saham |
| WELLINGTON MANAGEMENT GROUP LLP | $2.320.018 | 94.656 | 0,25% | Saham |
| Alessandra Capital Management, LLC | $2.288.459 | 93.368 | 0,24% | Saham |
| Russell Investments Group, Ltd. | $1.941.112 | 79.196 | 0,21% | Saham |
| CITADEL ADVISORS LLC | $1.920.726 | 78.365 | 0,20% | Saham |
| Caption Management, LLC | $1.838.250 | 75.000 | 0,19% | Opsi beli |
| BNP PARIBAS FINANCIAL MARKETS | $1.752.146 | 71.487 | 0,19% | Saham |
| Birchview Capital, LP | $1.691.190 | 69.000 | 0,18% | Saham |
| Squarepoint Ops LLC | $1.677.366 | 68.436 | 0,18% | Saham |
| TWO SIGMA INVESTMENTS, LP | $1.504.767 | 61.394 | 0,16% | Saham |
| BOOTHBAY FUND MANAGEMENT, LLC | $1.504.424 | 61.380 | 0,16% | Saham |
| AMERIPRISE FINANCIAL INC | $1.450.943 | 59.198 | 0,15% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.431.384 | 58.400 | 0,15% | Opsi jual |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.422.193 | 58.025 | 0,15% | Saham |
| AMERICAN CENTURY COMPANIES INC | $1.342.658 | 54.780 | 0,14% | Saham |
| AQR CAPITAL MANAGEMENT LLC | $1.254.618 | 51.188 | 0,13% | Saham |
| Quantinno Capital Management LP | $1.254.618 | 51.188 | 0,13% | Saham |
| SEVEN GRAND MANAGERS, LLC | $1.225.500 | 50.000 | 0,13% | Saham |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $1.214.348 | 49.545 | 0,13% | Saham |
| Moody Aldrich Partners LLC | $1.164.004 | 47.491 | 0,12% | Saham |
| SIMPLEX TRADING, LLC | $1.158.832 | 47.280 | 0,12% | Saham |
| RHUMBLINE ADVISERS | $1.076.080 | 43.904 | 0,11% | Saham |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1.029.420 | 42.000 | 0,11% | Saham |
| Corient Private Wealth LP | $986.724 | 40.258 | 0,10% | Saham |
| Persistent Asset Partners Ltd | $913.071 | 37.253 | 0,10% | Saham |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $866.183 | 35.340 | 0,09% | Saham |
| DEUTSCHE BANK AG\ | $840.644 | 34.298 | 0,09% | Saham |
| ALLIANCEBERNSTEIN L.P. | $799.293 | 45.700 | 0,08% | Saham |
| CITADEL ADVISORS LLC | $794.124 | 32.400 | 0,08% | Opsi jual |
| Militia Capital Management LLC | $791.330 | 32.286 | 0,08% | Saham |
| Vanguard Global Advisers, LLC | $781.011 | 31.865 | 0,08% | Saham |
| MARSHALL WACE, LLP | $778.021 | 31.743 | 0,08% | Saham |
| CITIGROUP INC | $746.869 | 30.472 | 0,08% | Saham |
| WELLS FARGO & COMPANY/MN | $727.800 | 29.694 | 0,08% | Saham |
| STATE OF WISCONSIN INVESTMENT BOARD | $689.883 | 28.147 | 0,07% | Saham |
| CITADEL ADVISORS LLC | $681.378 | 27.800 | 0,07% | Opsi beli |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $681.084 | 27.788 | 0,07% | Saham |
| XTX Topco Ltd | $656.696 | 26.793 | 0,07% | Saham |
| WEXFORD CAPITAL LP | $631.500 | 25.765 | 0,07% | Saham |
| BARCLAYS PLC | $627.947 | 25.620 | 0,07% | Saham |
| MILLENNIUM MANAGEMENT LLC | $612.750 | 25.000 | 0,06% | Opsi beli |
| JANE STREET GROUP, LLC | $590.421 | 24.089 | 0,06% | Saham |
| Caption Management, LLC | $569.612 | 23.240 | 0,06% | Saham |
| STRS OHIO | $539.220 | 22.000 | 0,06% | Saham |
| Militia Capital Partners, LP | $533.169 | 40.300 | 0,06% | Saham |
| MetLife Investment Management, LLC | $511.989 | 20.889 | 0,05% | Saham |
| Stonepine Capital Management, LLC | $490.200 | 20.000 | 0,05% | Saham |
| BANK OF NOVA SCOTIA | $490.200 | 20.000 | 0,05% | Saham |
| Creative Planning | $454.292 | 18.535 | 0,05% | Saham |
| Man Group plc | $444.783 | 18.147 | 0,05% | Saham |
| Virtus Investment Advisers, LLC | $444.538 | 18.137 | 0,05% | Saham |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $443.386 | 18.090 | 0,05% | Saham |
| Verdad Advisers, LP | $426.327 | 17.394 | 0,05% | Saham |
| JANE STREET GROUP, LLC | $409.317 | 16.700 | 0,04% | Opsi jual |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $396.743 | 16.187 | 0,04% | Saham |
| GREAT LAKES ADVISORS, LLC | $390.493 | 15.932 | 0,04% | Saham |
| Y-Intercept (Hong Kong) Ltd | $373.532 | 15.240 | 0,04% | Saham |
| Engineers Gate Manager LP | $343.508 | 14.015 | 0,04% | Saham |
| Persistent Asset Partners Ltd | $342.710 | 510 | 0,04% | Opsi beli |
| JANE STREET GROUP, LLC | $335.787 | 13.700 | 0,04% | Opsi beli |
| Valor Management LLC | $321.204 | 13.105 | 0,03% | Saham |
| NEW YORK STATE COMMON RETIREMENT FUND | $303.924 | 12.400 | 0,03% | Saham |
| NISA INVESTMENT ADVISORS, LLC | $293.556 | 11.977 | 0,03% | Saham |
| GLENMEDE TRUST CO NA | $268.629 | 10.960 | 0,03% | Saham |
| PROFUND ADVISORS LLC | $266.669 | 10.880 | 0,03% | Saham |
| TWO SIGMA ADVISERS, LP | $257.985 | 19.500 | 0,03% | Saham |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $256.669 | 10.472 | 0,03% | Saham |
| Police & Firemen's Retirement System of New Jersey | $254.095 | 10.367 | 0,03% | Saham |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $233.556 | 9.529 | 0,02% | Saham |
| Quadrature Capital Ltd | $232.355 | 9.480 | 0,02% | Saham |
| RWA WEALTH PARTNERS, LLC | $222.820 | 9.091 | 0,02% | Saham |
| China Universal Asset Management Co., Ltd. | $173.408 | 7.075 | 0,02% | Saham |
| State of Wyoming | $153.776 | 6.274 | 0,02% | Saham |
| Legal & General Group Plc | $83.653 | 3.413 | 0,01% | Saham |
| Tower Research Capital LLC (TRC) | $78.530 | 3.204 | 0,01% | Saham |
| Ameritas Investment Partners, Inc. | $78.187 | 3.190 | 0,01% | Saham |
| CWM, LLC | $64.328 | 3.678 | 0,01% | Saham |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $51.397 | 2.097 | 0,01% | Saham |
| Mirae Asset Global Investments Co., Ltd. | $48.726 | 1.988 | 0,01% | Saham |
| PNC Financial Services Group, Inc. | $48.382 | 1.974 | 0,01% | Saham |
| US BANCORP \DE\ | $32.132 | 1.311 | 0,00% | Saham |
| ROYAL BANK OF CANADA | $26.000 | 1.070 | 0,00% | Saham |
| SIGNATUREFD, LLC | $24.682 | 1.007 | 0,00% | Saham |
| GF FUND MANAGEMENT CO. LTD. | $22.574 | 921 | 0,00% | Saham |
| Parallel Advisors, LLC | $21.250 | 867 | 0,00% | Saham |
| Sterling Capital Management LLC | $15.956 | 651 | 0,00% | Saham |
| Arax Advisory Partners | $13.284 | 542 | 0,00% | Saham |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $10.368 | 423 | 0,00% | Saham |
| TD Waterhouse Canada Inc. | $6.212 | 256 | 0,00% | Saham |
| ACADIAN ASSET MANAGEMENT LLC | $5.499 | 224.453 | 0,00% | Saham |
| OSAIC HOLDINGS, INC. | $4.484 | 183 | 0,00% | Saham |
| Torren Management, LLC | $3.725 | 213 | 0,00% | Saham |
| EverSource Wealth Advisors, LLC | $3.555 | 145 | 0,00% | Saham |
| Farther Finance Advisors, LLC | $3.304 | 133 | 0,00% | Saham |
| Steward Partners Investment Advisory, LLC | $3.137 | 128 | 0,00% | Saham |
| NATIONAL BANK OF CANADA /FI/ | $3.064 | 125 | 0,00% | Saham |
| Truvestments Capital LLC | $2.917 | 119 | 0,00% | Saham |
| Cornerstone Financial Management LLC | $2.696 | 110 | 0,00% | Saham |
| Essential Partners LLC | $2.353 | 96 | 0,00% | Saham |
| GROUP ONE TRADING LLC | $2.353 | 96 | 0,00% | Saham |
| MassMutual Private Wealth & Trust, FSB | $2.328 | 95 | 0,00% | Saham |
| Cornerstone Planning Group LLC | $2.238 | 102 | 0,00% | Saham |
| ROTHSCHILD INVESTMENT LLC | $2.132 | 87 | 0,00% | Saham |
| True Wealth Design, LLC | $1.961 | 80 | 0,00% | Saham |
| PRICE T ROWE ASSOCIATES INC /MD/ | $717 | 29.247 | 0,00% | Saham |
| Silver Grove Financial Group, Inc. | $368 | 15 | 0,00% | Saham |
| FIFTH THIRD BANCORP | $270 | 11 | 0,00% | Saham |
| GAMMA Investing LLC | $221 | 9 | 0,00% | Saham |
| IFP Advisors, Inc | $221 | 9 | 0,00% | Saham |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $122 | 7 | 0,00% | Saham |
| Allworth Financial LP | $99 | 4 | 0,00% | Saham |
| SBI Securities Co., Ltd. | $98 | 4 | 0,00% | Saham |
| Sunbelt Securities, Inc. | $52 | 3 | 0,00% | Saham |