SION — Pemilik institusional (13F)
Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.
| Institusi | Nilai | Saham | % dari 13F yang dilacak | Tipe |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $435.722.930 | 9.905.045 | 20,30% | Saham |
| TPG GP A, LLC | $285.713.378 | 6.494.962 | 13,31% | Saham |
| VIKING GLOBAL INVESTORS LP | $140.556.012 | 3.195.181 | 6,55% | Saham |
| Atlas Venture Life Science Advisors, LLC | $131.776.532 | 2.995.602 | 6,14% | Saham |
| ORBIMED ADVISORS LLC | $112.433.029 | 2.555.877 | 5,24% | Saham |
| ENAVATE SCIENCES GP, LLC | $109.008.540 | 2.478.030 | 5,08% | Saham |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $70.384.000 | 1.600.000 | 3,28% | Saham |
| BlackRock, Inc. | $64.875.089 | 1.474.769 | 3,02% | Saham |
| JPMORGAN CHASE & CO | $64.085.673 | 1.490.508 | 2,99% | Saham |
| JENNISON ASSOCIATES LLC | $51.562.131 | 1.172.133 | 2,40% | Saham |
| CITADEL ADVISORS LLC | $50.484.507 | 1.147.636 | 2,35% | Saham |
| VANGUARD CAPITAL MANAGEMENT LLC | $49.796.724 | 1.132.001 | 2,32% | Saham |
| VANGUARD GROUP INC | $48.748.883 | 1.184.951 | 2,27% | Saham |
| STATE STREET CORP | $44.937.281 | 1.021.534 | 2,09% | Saham |
| PERCEPTIVE ADVISORS LLC | $39.810.950 | 905.000 | 1,85% | Saham |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $29.953.495 | 680.916 | 1,40% | Saham |
| Siren, L.L.C. | $26.856.555 | 610.515 | 1,25% | Saham |
| EVENTIDE ASSET MANAGEMENT, LLC | $20.894.402 | 474.981 | 0,97% | Saham |
| GEODE CAPITAL MANAGEMENT, LLC | $20.113.984 | 457.145 | 0,94% | Saham |
| Casdin Capital, LLC | $17.596.000 | 400.000 | 0,82% | Saham |
| BAKER BROS. ADVISORS LP | $17.596.000 | 400.000 | 0,82% | Saham |
| GOLDMAN SACHS GROUP INC | $17.103.752 | 388.810 | 0,80% | Saham |
| Driehaus Capital Management LLC | $16.955.814 | 385.447 | 0,79% | Saham |
| FRANKLIN RESOURCES INC | $12.762.071 | 290.113 | 0,59% | Saham |
| Aberdeen Group plc | $12.499.231 | 284.138 | 0,58% | Saham |
| FMR LLC | $12.242.065 | 278.292 | 0,57% | Saham |
| MILLENNIUM MANAGEMENT LLC | $12.173.485 | 276.733 | 0,57% | Saham |
| Candriam S.C.A. | $10.248.950 | 233.208 | 0,48% | Saham |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $9.807.527 | 222.949 | 0,46% | Saham |
| Kalehua Capital Management LLC | $8.669.197 | 197.072 | 0,40% | Saham |
| Longaeva Partners L.P. | $8.637.524 | 196.352 | 0,40% | Saham |
| Artisan Partners Limited Partnership | $8.336.017 | 189.498 | 0,39% | Saham |
| Ensign Peak Advisors, Inc | $8.117.563 | 184.532 | 0,38% | Saham |
| Soleus Capital Management, L.P. | $7.816.451 | 177.687 | 0,36% | Saham |
| NORTHERN TRUST CORP | $6.795.399 | 154.476 | 0,32% | Saham |
| MORGAN STANLEY | $6.644.558 | 151.047 | 0,31% | Saham |
| Sofinnova Investments, Inc. | $6.353.564 | 144.432 | 0,30% | Saham |
| Qube Research & Technologies Ltd | $6.172.193 | 140.309 | 0,29% | Saham |
| Alyeska Investment Group, L.P. | $5.992.406 | 136.222 | 0,28% | Saham |
| GordonMD Global Investments LP | $5.982.640 | 136.000 | 0,28% | Saham |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $5.707.834 | 129.753 | 0,27% | Saham |
| Sio Capital Management, LLC | $5.622.274 | 127.808 | 0,26% | Saham |
| VANGUARD FIDUCIARY TRUST CO | $5.342.234 | 121.442 | 0,25% | Saham |
| Artia Global Partners LP | $5.267.407 | 119.741 | 0,25% | Saham |
| UBS Group AG | $5.111.902 | 116.206 | 0,24% | Saham |
| First Turn Management, LLC | $4.860.587 | 110.493 | 0,23% | Saham |
| CITIGROUP INC | $4.846.070 | 110.163 | 0,23% | Saham |
| Ikarian Capital, LLC | $4.728.925 | 107.500 | 0,22% | Opsi jual |
| D. E. Shaw & Co., Inc. | $4.471.320 | 101.644 | 0,21% | Saham |
| Rock Springs Capital Management LP | $4.373.882 | 99.429 | 0,20% | Saham |
| Walleye Capital LLC | $4.282.295 | 97.347 | 0,20% | Saham |
| Rhenman & Partners Asset Management AB | $4.271.429 | 97.100 | 0,20% | Saham |
| BANK OF AMERICA CORP /DE/ | $3.911.063 | 88.908 | 0,18% | Saham |
| AMERIPRISE FINANCIAL INC | $3.617.386 | 82.232 | 0,17% | Saham |
| Integral Health Asset Management, LLC | $3.299.250 | 75.000 | 0,15% | Saham |
| SUPERSTRING CAPITAL MANAGEMENT LP | $2.778.232 | 63.156 | 0,13% | Saham |
| STEMPOINT CAPITAL LP | $2.614.150 | 59.426 | 0,12% | Saham |
| DEUTSCHE BANK AG\ | $2.346.998 | 53.353 | 0,11% | Saham |
| SEVEN GRAND MANAGERS, LLC | $2.199.500 | 50.000 | 0,10% | Saham |
| Point72 Asset Management, L.P. | $2.169.939 | 49.328 | 0,10% | Saham |
| TD Asset Management Inc | $2.084.950 | 47.396 | 0,10% | Saham |
| ALPS ADVISORS INC | $2.002.645 | 45.525 | 0,09% | Saham |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1.868.607 | 42.478 | 0,09% | Saham |
| Russell Investments Group, Ltd. | $1.858.960 | 42.258 | 0,09% | Saham |
| Bank of New York Mellon Corp | $1.829.361 | 41.586 | 0,09% | Saham |
| Nuveen, LLC | $1.814.984 | 41.259 | 0,08% | Saham |
| XTX Topco Ltd | $1.675.843 | 38.096 | 0,08% | Saham |
| WELLINGTON MANAGEMENT GROUP LLP | $1.643.686 | 37.365 | 0,08% | Saham |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $1.582.232 | 35.968 | 0,07% | Saham |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.558.126 | 35.420 | 0,07% | Saham |
| BOOTHBAY FUND MANAGEMENT, LLC | $1.429.675 | 32.500 | 0,07% | Opsi jual |
| BNP PARIBAS FINANCIAL MARKETS | $1.399.014 | 31.803 | 0,07% | Saham |
| Ishara Investments LP | $1.350.540 | 123.000 | 0,06% | Saham |
| MILLENNIUM MANAGEMENT LLC | $1.258.114 | 28.600 | 0,06% | Opsi jual |
| Swiss National Bank | $1.187.730 | 27.000 | 0,06% | Saham |
| Quadrature Capital Ltd | $1.144.752 | 26.023 | 0,05% | Saham |
| Trexquant Investment LP | $1.047.402 | 23.810 | 0,05% | Saham |
| NEW YORK STATE COMMON RETIREMENT FUND | $1.037.548 | 23.586 | 0,05% | Saham |
| ALLIANCEBERNSTEIN L.P. | $1.020.291 | 25.450 | 0,05% | Saham |
| TUDOR INVESTMENT CORP ET AL | $993.074 | 22.575 | 0,05% | Saham |
| RHUMBLINE ADVISERS | $981.362 | 22.309 | 0,05% | Saham |
| MILLENNIUM MANAGEMENT LLC | $879.800 | 20.000 | 0,04% | Opsi beli |
| Maven Securities LTD | $879.800 | 20.000 | 0,04% | Saham |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $820.193 | 18.645 | 0,04% | Saham |
| Susquehanna Portfolio Strategies, LLC | $793.316 | 18.034 | 0,04% | Saham |
| Rafferty Asset Management, LLC | $791.996 | 18.004 | 0,04% | Saham |
| Shay Capital LLC | $791.820 | 18.000 | 0,04% | Saham |
| WELLS FARGO & COMPANY/MN | $739.955 | 16.821 | 0,03% | Saham |
| Engineers Gate Manager LP | $686.376 | 15.603 | 0,03% | Saham |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $653.339 | 14.852 | 0,03% | Saham |
| KENNEDY CAPITAL MANAGEMENT LLC | $555.198 | 12.621 | 0,03% | Saham |
| MARSHALL WACE, LLP | $554.230 | 12.599 | 0,03% | Saham |
| Invesco Ltd. | $546.267 | 12.418 | 0,03% | Saham |
| MetLife Investment Management, LLC | $482.658 | 10.972 | 0,02% | Saham |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $463.369 | 10.582 | 0,02% | Saham |
| Jump Financial, LLC | $460.708 | 10.473 | 0,02% | Saham |
| VANGUARD ASSET MANAGEMENT, Ltd | $419.445 | 9.535 | 0,02% | Saham |
| PROFUND ADVISORS LLC | $402.069 | 9.140 | 0,02% | Saham |
| Virtus Investment Advisers, LLC | $400.705 | 9.109 | 0,02% | Saham |
| Legal & General Group Plc | $397.846 | 9.044 | 0,02% | Saham |
| CITADEL ADVISORS LLC | $369.516 | 8.400 | 0,02% | Opsi jual |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $356.319 | 8.100 | 0,02% | Opsi beli |
| Vanguard Global Advisers, LLC | $345.409 | 7.852 | 0,02% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $338.723 | 7.700 | 0,02% | Opsi jual |
| China Universal Asset Management Co., Ltd. | $316.112 | 7.186 | 0,01% | Saham |
| Quarry LP | $296.933 | 6.750 | 0,01% | Saham |
| BARCLAYS PLC | $285.715 | 6.495 | 0,01% | Saham |
| VARCOV Co. | $282.328 | 6.418 | 0,01% | Saham |
| Police & Firemen's Retirement System of New Jersey | $239.218 | 5.438 | 0,01% | Saham |
| Squarepoint Ops LLC | $238.206 | 5.415 | 0,01% | Saham |
| INTECH INVESTMENT MANAGEMENT LLC | $229.540 | 5.218 | 0,01% | Saham |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $229.408 | 5.215 | 0,01% | Saham |
| SEI INVESTMENTS CO | $226.900 | 5.158 | 0,01% | Saham |
| Verition Fund Management LLC | $219.950 | 5.000 | 0,01% | Opsi beli |
| AlphaCentric Advisors LLC | $213.923 | 4.863 | 0,01% | Saham |
| Jain Global LLC | $210.272 | 4.780 | 0,01% | Saham |
| AXQ CAPITAL, LP | $202.222 | 4.597 | 0,01% | Saham |
| STRS OHIO | $153.965 | 3.500 | 0,01% | Saham |
| Vanguard Investments Australia, Ltd. | $153.525 | 3.490 | 0,01% | Saham |
| KLP KAPITALFORVALTNING AS | $136.369 | 3.100 | 0,01% | Saham |
| Mirae Asset Global Investments Co., Ltd. | $88.816 | 2.019 | 0,00% | Saham |
| Quantbot Technologies LP | $80.062 | 1.820 | 0,00% | Saham |
| Ameritas Investment Partners, Inc. | $73.595 | 1.673 | 0,00% | Saham |
| Tower Research Capital LLC (TRC) | $56.263 | 1.279 | 0,00% | Saham |
| Mitsubishi UFJ Asset Management Co., Ltd. | $43.990 | 1.000 | 0,00% | Saham |
| GF FUND MANAGEMENT CO. LTD. | $41.615 | 946 | 0,00% | Saham |
| State of Wyoming | $35.368 | 804 | 0,00% | Saham |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $31.189 | 709 | 0,00% | Saham |
| ROYAL BANK OF CANADA | $25.000 | 568 | 0,00% | Saham |
| PRICE T ROWE ASSOCIATES INC /MD/ | $21.029 | 478.016 | 0,00% | Saham |
| NISA INVESTMENT ADVISORS, LLC | $16.936 | 385 | 0,00% | Saham |
| GAMMA Investing LLC | $10.734 | 244 | 0,00% | Saham |
| Federation des caisses Desjardins du Quebec | $9.238 | 210 | 0,00% | Saham |
| Farther Finance Advisors, LLC | $8.622 | 196 | 0,00% | Saham |
| Rockefeller Capital Management L.P. | $5.015 | 114 | 0,00% | Saham |
| Hurley Capital, LLC | $4.971 | 113 | 0,00% | Saham |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $4.650 | 116 | 0,00% | Saham |
| US BANCORP \DE\ | $4.575 | 104 | 0,00% | Saham |
| Sterling Capital Management LLC | $2.859 | 65 | 0,00% | Saham |
| CWM, LLC | $2.686 | 67 | 0,00% | Saham |
| Arax Advisory Partners | $1.804 | 41 | 0,00% | Saham |
| Bare Financial Services, Inc | $1.628 | 37 | 0,00% | Saham |
| Caitong International Asset Management Co., Ltd | $1.364 | 31 | 0,00% | Saham |
| Hughes Financial Services, LLC | $1.100 | 25 | 0,00% | Saham |
| EverSource Wealth Advisors, LLC | $880 | 20 | 0,00% | Saham |
| Fortitude Family Office, LLC | $660 | 15 | 0,00% | Saham |
| SJS Investment Consulting Inc. | $396 | 9 | 0,00% | Saham |
| CONTRAVISORY INVESTMENT MANAGEMENT, INC. | $264 | 6 | 0,00% | Saham |
| PNC Financial Services Group, Inc. | $220 | 5 | 0,00% | Saham |
| Steward Partners Investment Advisory, LLC | $176 | 4 | 0,00% | Saham |
| NATIONAL BANK OF CANADA /FI/ | $88 | 2 | 0,00% | Saham |
| ROTHSCHILD INVESTMENT LLC | $44 | 1 | 0,00% | Saham |
| Allworth Financial LP | $44 | 1 | 0,00% | Saham |
| Pacer Advisors, Inc. | $13 | 301 | 0,00% | Saham |
| Covestor Ltd | $1 | 12 | 0,00% | Saham |