| Flagship Pioneering, LLC |
$61,849,706 |
12,674,120 |
26.98% |
주식
|
| BVF INC/IL |
$28,508,960 |
5,842,000 |
12.44% |
주식
|
| FMR LLC |
$27,845,075 |
5,705,958 |
12.15% |
주식
|
| DEERFIELD MANAGEMENT COMPANY, L.P. |
$21,444,511 |
4,394,367 |
9.35% |
주식
|
| BlackRock, Inc. |
$12,818,939 |
2,626,832 |
5.59% |
주식
|
| RAYMOND JAMES FINANCIAL INC |
$12,151,093 |
2,489,978 |
5.30% |
주식
|
| VANGUARD GROUP INC |
$10,416,557 |
1,928,992 |
4.54% |
주식
|
| Euclidean Capital LLC |
$7,679,954 |
1,573,761 |
3.35% |
주식
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$7,293,702 |
1,494,611 |
3.18% |
주식
|
| GEODE CAPITAL MANAGEMENT, LLC |
$4,446,091 |
910,866 |
1.94% |
주식
|
| Siren, L.L.C. |
$3,517,114 |
720,720 |
1.53% |
주식
|
| STATE STREET CORP |
$3,403,649 |
697,469 |
1.48% |
주식
|
| AMERIPRISE FINANCIAL INC |
$2,726,383 |
558,685 |
1.19% |
주식
|
| RENAISSANCE TECHNOLOGIES LLC |
$1,844,328 |
377,936 |
0.80% |
주식
|
| Candriam S.C.A. |
$1,529,700 |
313,765 |
0.67% |
주식
|
| NORTHERN TRUST CORP |
$1,511,703 |
309,775 |
0.66% |
주식
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$1,490,518 |
305,434 |
0.65% |
주식
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$1,485,628 |
304,432 |
0.65% |
주식
|
| Birchview Capital, LP |
$1,375,853 |
281,937 |
0.60% |
주식
|
| VANGUARD FIDUCIARY TRUST CO |
$1,290,379 |
264,422 |
0.56% |
주식
|
| Qube Research & Technologies Ltd |
$992,084 |
203,296 |
0.43% |
주식
|
| Woodline Partners LP |
$986,468 |
202,145 |
0.43% |
주식
|
| B Group, Inc. |
$976,000 |
200,000 |
0.43% |
주식
|
| PANAGORA ASSET MANAGEMENT INC |
$855,981 |
175,406 |
0.37% |
주식
|
| GOLDMAN SACHS GROUP INC |
$801,569 |
164,256 |
0.35% |
주식
|
| CITADEL ADVISORS LLC |
$775,051 |
158,822 |
0.34% |
주식
|
| Squarepoint Ops LLC |
$636,088 |
130,346 |
0.28% |
주식
|
| DAFNA Capital Management LLC |
$545,872 |
111,859 |
0.24% |
주식
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$535,731 |
109,781 |
0.23% |
주식
|
| SCS Capital Management LLC |
$522,062 |
106,980 |
0.23% |
주식
|
| MORGAN STANLEY |
$449,429 |
92,096 |
0.20% |
주식
|
| Palumbo Wealth Management LLC |
$447,687 |
91,739 |
0.20% |
주식
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$437,248 |
89,600 |
0.19% |
주식
|
| Bank of New York Mellon Corp |
$387,253 |
79,355 |
0.17% |
주식
|
| Invesco Ltd. |
$381,298 |
78,135 |
0.17% |
주식
|
| DIADEMA PARTNERS LP |
$326,511 |
66,908 |
0.14% |
주식
|
| AQR CAPITAL MANAGEMENT LLC |
$323,247 |
66,239 |
0.14% |
주식
|
| Nuveen, LLC |
$317,390 |
65,039 |
0.14% |
주식
|
| Lynx1 Capital Management LP |
$300,549 |
61,588 |
0.13% |
주식
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$283,499 |
58,094 |
0.12% |
주식
|
| MILLENNIUM MANAGEMENT LLC |
$261,124 |
53,509 |
0.11% |
주식
|
| Verdad Advisers, LP |
$259,767 |
53,231 |
0.11% |
주식
|
| Persistent Asset Partners Ltd |
$228,735 |
46,872 |
0.10% |
주식
|
| SILVERARC CAPITAL MANAGEMENT, LLC |
$224,358 |
45,975 |
0.10% |
주식
|
| RHUMBLINE ADVISERS |
$193,152 |
39,582 |
0.08% |
주식
|
| DEUTSCHE BANK AG\ |
$178,301 |
36,537 |
0.08% |
주식
|
| Jump Financial, LLC |
$177,549 |
36,383 |
0.08% |
주식
|
| WELLS FARGO & COMPANY/MN |
$172,268 |
35,301 |
0.08% |
주식
|
| ALLIANCEBERNSTEIN L.P. |
$142,253 |
29,760 |
0.06% |
주식
|
| BANK OF AMERICA CORP /DE/ |
$127,383 |
26,103 |
0.06% |
주식
|
| CANADA PENSION PLAN INVESTMENT BOARD |
$122,488 |
25,100 |
0.05% |
주식
|
| JPMORGAN CHASE & CO |
$99,304 |
20,433 |
0.04% |
주식
|
| BARCLAYS PLC |
$93,642 |
19,189 |
0.04% |
주식
|
| CITIGROUP INC |
$90,494 |
18,544 |
0.04% |
주식
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$82,091 |
16,822 |
0.04% |
주식
|
| EntryPoint Capital, LLC |
$75,557 |
15,483 |
0.03% |
주식
|
| DIVERSIFIED TRUST CO |
$72,370 |
14,830 |
0.03% |
주식
|
| Russell Investments Group, Ltd. |
$70,413 |
14,429 |
0.03% |
주식
|
| Vanguard Global Advisers, LLC |
$62,625 |
12,833 |
0.03% |
주식
|
| TWO SIGMA INVESTMENTS, LP |
$60,732 |
12,445 |
0.03% |
주식
|
| TWO SIGMA ADVISERS, LP |
$56,160 |
10,400 |
0.02% |
주식
|
| Police & Firemen's Retirement System of New Jersey |
$55,271 |
11,326 |
0.02% |
주식
|
| UBS Group AG |
$54,808 |
11,231 |
0.02% |
주식
|
| Fiduciary Trust Co |
$53,090 |
10,879 |
0.02% |
주식
|
| BNP PARIBAS FINANCIAL MARKETS |
$51,025 |
10,456 |
0.02% |
주식
|
| China Universal Asset Management Co., Ltd. |
$45,599 |
9,344 |
0.02% |
주식
|
| STRS OHIO |
$41,968 |
8,600 |
0.02% |
주식
|
| Evelyn Partners Asset Management Ltd |
$33,938 |
7,100 |
0.01% |
주식
|
| Ameritas Investment Partners, Inc. |
$16,314 |
3,343 |
0.01% |
주식
|
| Tower Research Capital LLC (TRC) |
$16,016 |
3,282 |
0.01% |
주식
|
| CWM, LLC |
$15,989 |
3,345 |
0.01% |
주식
|
| Legal & General Group Plc |
$14,567 |
2,985 |
0.01% |
주식
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$13,747 |
2,876 |
0.01% |
주식
|
| Mirae Asset Global Investments Co., Ltd. |
$12,815 |
2,626 |
0.01% |
주식
|
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
$10,985 |
2,251 |
0.00% |
주식
|
| SIMPLEX TRADING, LLC |
$9,232 |
1,892 |
0.00% |
주식
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$9,130 |
1,871 |
0.00% |
주식
|
| GF FUND MANAGEMENT CO. LTD. |
$6,056 |
1,241 |
0.00% |
주식
|
| Arax Advisory Partners |
$5,544 |
1,136 |
0.00% |
주식
|
| TD Waterhouse Canada Inc. |
$5,010 |
1,000 |
0.00% |
주식
|
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC |
$5,010 |
1,000 |
0.00% |
주식
|
| ROYAL BANK OF CANADA |
$5,000 |
1,097 |
0.00% |
주식
|
| Sunbelt Securities, Inc. |
$4,780 |
1,000 |
0.00% |
주식
|
| GAMMA Investing LLC |
$3,099 |
635 |
0.00% |
주식
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$2,362 |
484 |
0.00% |
주식
|
| Bare Financial Services, Inc |
$1,205 |
247 |
0.00% |
주식
|
| Allworth Financial LP |
$1,172 |
240 |
0.00% |
주식
|
| NATIONAL BANK OF CANADA /FI/ |
$974 |
200 |
0.00% |
주식
|
| EverSource Wealth Advisors, LLC |
$883 |
181 |
0.00% |
주식
|
| PNC Financial Services Group, Inc. |
$625 |
128 |
0.00% |
주식
|
| Sterling Capital Management LLC |
$625 |
128 |
0.00% |
주식
|
| TFC Financial Management, Inc. |
$601 |
123 |
0.00% |
주식
|
| SBI Securities Co., Ltd. |
$488 |
100 |
0.00% |
주식
|
| NISA INVESTMENT ADVISORS, LLC |
$381 |
78 |
0.00% |
주식
|
| Farther Finance Advisors, LLC |
$317 |
65 |
0.00% |
주식
|
| ACADIAN ASSET MANAGEMENT LLC |
$187 |
38,784 |
0.00% |
주식
|
| Essential Partners LLC |
$171 |
35 |
0.00% |
주식
|
| ROTHSCHILD INVESTMENT LLC |
$161 |
33 |
0.00% |
주식
|
| GSA CAPITAL PARTNERS LLP |
$144 |
29,506 |
0.00% |
주식
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$120 |
24,478 |
0.00% |
주식
|
| Caitong International Asset Management Co., Ltd |
$83 |
17 |
0.00% |
주식
|
| True Wealth Design, LLC |
$69 |
14 |
0.00% |
주식
|
| Clearstead Advisors, LLC |
$44 |
9 |
0.00% |
주식
|
| SJS Investment Consulting Inc. |
$44 |
9 |
0.00% |
주식
|
| Optiver Holding B.V. |
$29 |
6 |
0.00% |
주식
|
| OSAIC HOLDINGS, INC. |
$24 |
5 |
0.00% |
주식
|