| MORGAN STANLEY |
$41410468 |
8867338 |
7.60% |
股份
|
| RA CAPITAL MANAGEMENT, L.P. |
$37360000 |
8000000 |
6.86% |
股份
|
| BlackRock, Inc. |
$36877672 |
7896718 |
6.77% |
股份
|
| Lynx1 Capital Management LP |
$34215647 |
7326691 |
6.28% |
股份
|
| Squadron Capital Management LLC |
$33624000 |
7200000 |
6.17% |
股份
|
| Bain Capital Life Sciences Investors, LLC |
$33492820 |
7171910 |
6.15% |
股份
|
| JPMORGAN CHASE & CO |
$20651295 |
4747424 |
3.79% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$20630804 |
4417731 |
3.79% |
股份
|
| CITADEL ADVISORS LLC |
$19555999 |
4187580 |
3.59% |
股份
|
| GOLDMAN SACHS GROUP INC |
$16489728 |
3530991 |
3.03% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$16203532 |
3469707 |
2.97% |
股份
|
| Soleus Capital Management, L.P. |
$15775171 |
3377981 |
2.90% |
股份
|
| SILVERARC CAPITAL MANAGEMENT, LLC |
$14159720 |
3032060 |
2.60% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$12405197 |
2656359 |
2.28% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$11780697 |
2522163 |
2.16% |
股份
|
| Ikarian Capital, LLC |
$11362110 |
2433000 |
2.09% |
股份
|
| STATE STREET CORP |
$9879950 |
2115621 |
1.81% |
股份
|
| Candriam S.C.A. |
$8383622 |
1796937 |
1.54% |
股份
|
| VANGUARD GROUP INC |
$8365446 |
4379815 |
1.54% |
股份
|
| D. E. Shaw & Co., Inc. |
$8130419 |
1740989 |
1.49% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$8089421 |
1732210 |
1.49% |
股份
|
| WASATCH ADVISORS LP |
$7789431 |
2961761 |
1.43% |
股份
|
| Patient Square Capital LP |
$7513166 |
1608815 |
1.38% |
股份
|
| HighVista Strategies LLC |
$6295800 |
1348136 |
1.16% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$5556497 |
1189828 |
1.02% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$5546166 |
1188507 |
1.02% |
股份
|
| NORTHERN TRUST CORP |
$5419754 |
1160547 |
0.99% |
股份
|
| CONGRESS ASSET MANAGEMENT CO |
$4686051 |
1003437 |
0.86% |
股份
|
| FMR LLC |
$4175231 |
894054 |
0.77% |
股份
|
| UBS Group AG |
$3871289 |
828970 |
0.71% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$3647550 |
781060 |
0.67% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$3438666 |
736331 |
0.63% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$3176039 |
680094 |
0.58% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$2844712 |
609146 |
0.52% |
股份
|
| ExodusPoint Capital Management, LP |
$2709511 |
580195 |
0.50% |
股份
|
| Velan Capital Investment Management LP |
$2661900 |
570000 |
0.49% |
股份
|
| STEMPOINT CAPITAL LP |
$2445436 |
523648 |
0.45% |
股份
|
| Rockefeller Capital Management L.P. |
$2315465 |
495817 |
0.43% |
股份
|
| Nuveen, LLC |
$2260326 |
484010 |
0.41% |
股份
|
| WELLS FARGO & COMPANY/MN |
$2114113 |
452701 |
0.39% |
股份
|
| TWO SIGMA ADVISERS, LP |
$2040262 |
1068200 |
0.37% |
股份
|
| Man Group plc |
$1908386 |
408648 |
0.35% |
股份
|
| Squadron Capital Management LLC |
$1868000 |
400000 |
0.34% |
买入期权
|
| PLATINUM INVESTMENT MANAGEMENT LTD |
$1796857 |
384766 |
0.33% |
股份
|
| Seven Fleet Capital Management LP |
$1780059 |
381169 |
0.33% |
股份
|
| Qube Research & Technologies Ltd |
$1730487 |
370554 |
0.32% |
股份
|
| Atom Investors LP |
$1701519 |
364351 |
0.31% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$1564819 |
335079 |
0.29% |
股份
|
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
$1517750 |
325000 |
0.28% |
股份
|
| JANE STREET GROUP, LLC |
$1413843 |
302750 |
0.26% |
股份
|
| Connor, Clark & Lunn Investment Management Ltd. |
$1404428 |
300734 |
0.26% |
股份
|
| ADAR1 Capital Management, LLC |
$1363439 |
291957 |
0.25% |
股份
|
| Invesco Ltd. |
$1355356 |
290226 |
0.25% |
股份
|
| PANAGORA ASSET MANAGEMENT INC |
$1237302 |
264947 |
0.23% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$1210931 |
259300 |
0.22% |
买入期权
|
| LPL Financial LLC |
$1182281 |
253165 |
0.22% |
股份
|
| Bank of New York Mellon Corp |
$1165245 |
249517 |
0.21% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$1063676 |
227768 |
0.20% |
股份
|
| MARSHALL WACE, LLP |
$1060104 |
227003 |
0.19% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$1005853 |
215386 |
0.18% |
股份
|
| Jump Financial, LLC |
$853209 |
182700 |
0.16% |
股份
|
| Caption Management, LLC |
$825656 |
176800 |
0.15% |
买入期权
|
| Point72 Asset Management, L.P. |
$812417 |
173965 |
0.15% |
股份
|
| Squarepoint Ops LLC |
$797795 |
170834 |
0.15% |
股份
|
| Headlands Technologies LLC |
$719049 |
153972 |
0.13% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$703680 |
150681 |
0.13% |
股份
|
| XTX Topco Ltd |
$632495 |
135438 |
0.12% |
股份
|
| Palumbo Wealth Management LLC |
$618388 |
132417 |
0.11% |
股份
|
| RHUMBLINE ADVISERS |
$615859 |
131877 |
0.11% |
股份
|
| BRIDGEWAY CAPITAL MANAGEMENT, LLC |
$612237 |
131100 |
0.11% |
股份
|
| Walleye Capital LLC |
$537634 |
115125 |
0.10% |
股份
|
| ALPS ADVISORS INC |
$524039 |
112214 |
0.10% |
股份
|
| CANADA PENSION PLAN INVESTMENT BOARD |
$474005 |
101500 |
0.09% |
股份
|
| DEUTSCHE BANK AG\ |
$461737 |
98873 |
0.08% |
股份
|
| Verition Fund Management LLC |
$443650 |
95000 |
0.08% |
股份
|
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group |
$396950 |
85000 |
0.07% |
股份
|
| BARCLAYS PLC |
$347989 |
74516 |
0.06% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$347322 |
74373 |
0.06% |
股份
|
| CITADEL ADVISORS LLC |
$336707 |
72100 |
0.06% |
卖出期权
|
| Crestwood Advisors Group, LLC |
$310723 |
66536 |
0.06% |
股份
|
| Cubist Systematic Strategies, LLC |
$307819 |
138657 |
0.06% |
股份
|
| CV Advisors LLC |
$303550 |
65000 |
0.06% |
股份
|
| INTREPID FAMILY OFFICE LLC |
$303550 |
65000 |
0.06% |
股份
|
| MetLife Investment Management, LLC |
$286705 |
61393 |
0.05% |
股份
|
| Jain Global LLC |
$268815 |
57562 |
0.05% |
股份
|
| JANE STREET GROUP, LLC |
$234901 |
50300 |
0.04% |
买入期权
|
| CITIGROUP INC |
$230647 |
49389 |
0.04% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$217034 |
46474 |
0.04% |
股份
|
| SEI INVESTMENTS CO |
$197896 |
42376 |
0.04% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$178861 |
38300 |
0.03% |
卖出期权
|
| Quadrature Capital Ltd |
$171510 |
36726 |
0.03% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$170371 |
64780 |
0.03% |
股份
|
| Caption Management, LLC |
$163450 |
35000 |
0.03% |
股份
|
| Vanguard Global Advisers, LLC |
$157995 |
33832 |
0.03% |
股份
|
| Dynamic Technology Lab Private Ltd |
$153000 |
32828 |
0.03% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$145867 |
31235 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$139600 |
29893 |
0.03% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$128486 |
27513 |
0.02% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$117268 |
25111 |
0.02% |
股份
|
| Cresset Asset Management, LLC |
$116750 |
25000 |
0.02% |
股份
|
| CITADEL ADVISORS LLC |
$114882 |
24600 |
0.02% |
买入期权
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$112547 |
24100 |
0.02% |
股份
|
| StoneX Group Inc. |
$102297 |
22420 |
0.02% |
股份
|
| GROUP ONE TRADING LLC |
$101680 |
21773 |
0.02% |
股份
|
| Scientech Research LLC |
$99284 |
21260 |
0.02% |
股份
|
| Quantbot Technologies LP |
$97262 |
20827 |
0.02% |
股份
|
| PRELUDE CAPITAL MANAGEMENT, LLC |
$91999 |
19700 |
0.02% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$91541 |
19602 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$90561 |
19392 |
0.02% |
股份
|
| Callan Family Office, LLC |
$89412 |
19146 |
0.02% |
股份
|
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC |
$87796 |
18800 |
0.02% |
股份
|
| LANARK FINANCIAL, INC. |
$84060 |
18000 |
0.02% |
股份
|
| China Universal Asset Management Co., Ltd. |
$82178 |
17597 |
0.02% |
股份
|
| ProShare Advisors LLC |
$78900 |
16895 |
0.01% |
股份
|
| State of Wyoming |
$75154 |
16093 |
0.01% |
股份
|
| ALGERT GLOBAL LLC |
$74907 |
16040 |
0.01% |
股份
|
| HSBC HOLDINGS PLC |
$70257 |
13629 |
0.01% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$67365 |
14425 |
0.01% |
股份
|
| EWA, LLC |
$65982 |
14129 |
0.01% |
股份
|
| Northern Lights Advisors, Inc. |
$60383 |
12930 |
0.01% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$55386 |
11860 |
0.01% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$54088 |
11582 |
0.01% |
股份
|
| WINTON GROUP Ltd |
$51837 |
11100 |
0.01% |
股份
|
| AXQ CAPITAL, LP |
$50179 |
10745 |
0.01% |
股份
|
| Bronte Capital Management Pty Ltd. |
$48330 |
10349 |
0.01% |
股份
|
| Point72 Asia (Singapore) Pte. Ltd. |
$48192 |
21708 |
0.01% |
股份
|
| Abel Hall, LLC |
$47788 |
10233 |
0.01% |
股份
|
| Simplicity Wealth,LLC |
$46910 |
10045 |
0.01% |
股份
|
| Corient Private Wealth LP |
$46733 |
10007 |
0.01% |
股份
|
| PFG Investments, LLC |
$46700 |
10000 |
0.01% |
股份
|
| Legal & General Group Plc |
$45925 |
9834 |
0.01% |
股份
|
| OSAIC HOLDINGS, INC. |
$45161 |
9672 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$42955 |
9198 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$38616 |
8269 |
0.01% |
股份
|
| Russell Investments Group, Ltd. |
$37850 |
8105 |
0.01% |
股份
|
| WOLVERINE TRADING, LLC |
$28990 |
13000 |
0.01% |
买入期权
|
| WOLVERINE TRADING, LLC |
$28343 |
12710 |
0.01% |
股份
|
| Federation des caisses Desjardins du Quebec |
$27086 |
5800 |
0.00% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$23093 |
4945 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$17270 |
3698 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$17000 |
3634 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$11617 |
2727 |
0.00% |
股份
|
| Owl Creek Wealth Partners LLC |
$9994 |
2140 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$9541 |
2043 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$9396 |
2012 |
0.00% |
股份
|
| FEDERATED HERMES, INC. |
$8770 |
1878 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$8429 |
1806199 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$6519 |
1396 |
0.00% |
股份
|
| HUNTINGTON NATIONAL BANK |
$4918 |
107 |
0.00% |
股份
|
| CDC Financial, Inc. |
$4670 |
1000 |
0.00% |
股份
|
| SUMMIT SECURITIES GROUP LLC |
$3871 |
829 |
0.00% |
股份
|
| TORONTO DOMINION BANK |
$2989 |
640 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$2031 |
435 |
0.00% |
股份
|
| Optiver Holding B.V. |
$1672 |
358 |
0.00% |
股份
|
| Walleye Capital LLC |
$1401 |
300 |
0.00% |
买入期权
|
| NISA INVESTMENT ADVISORS, LLC |
$729 |
156 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$728 |
155881 |
0.00% |
股份
|
| Point72 (DIFC) Ltd |
$519 |
234 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$476 |
102 |
0.00% |
股份
|
| Virtu Financial LLC |
$458 |
98094 |
0.00% |
股份
|
| Thrivent Financial for Lutherans |
$247 |
52763 |
0.00% |
股份
|
| Arax Advisory Partners |
$89 |
19 |
0.00% |
股份
|