IVA — 机构持有人 (13F)
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| Caligan Partners LP | $30856862 | 8163191 | 9.39% | 股份 |
| SAMSARA BIOCAPITAL, LLC | $23869963 | 6314805 | 7.26% | 股份 |
| Paradigm Biocapital Advisors LP | $15120000 | 4000000 | 4.60% | 股份 |
| ANDERA PARTNERS | $13733424 | 3633181 | 4.18% | 股份 |
| ADAR1 Capital Management, LLC | $13633160 | 3606656 | 4.15% | 股份 |
| MILLENNIUM MANAGEMENT LLC | $13276018 | 3512174 | 4.04% | 股份 |
| SymBiosis Capital Partners, LLC | $13064700 | 2354000 | 3.98% | 股份 |
| Nantahala Capital Management, LLC | $10154566 | 2686393 | 3.09% | 股份 |
| Trails Edge Capital Partners, LP | $10047228 | 2657997 | 3.06% | 股份 |
| FRANKLIN RESOURCES INC | $9989070 | 2642611 | 3.04% | 股份 |
| Squadron Capital Management LLC | $9204300 | 2435000 | 2.80% | 股份 |
| Woodline Partners LP | $8781503 | 2323149 | 2.67% | 股份 |
| Aberdeen Group plc | $8723382 | 2307773 | 2.65% | 股份 |
| UBS Group AG | $8713626 | 2305192 | 2.65% | 股份 |
| BOOTHBAY FUND MANAGEMENT, LLC | $7574296 | 2003782 | 2.30% | 股份 |
| Patient Square Capital LP | $7435906 | 1967171 | 2.26% | 股份 |
| NEXTBio Capital Management LP | $6758580 | 1787984 | 2.06% | 股份 |
| CITADEL ADVISORS LLC | $6745659 | 1784566 | 2.05% | 股份 |
| AMERIPRISE FINANCIAL INC | $6415219 | 1697148 | 1.95% | 股份 |
| Point72 Asset Management, L.P. | $6361785 | 1683012 | 1.94% | 股份 |
| Integral Health Asset Management, LLC | $5745600 | 1520000 | 1.75% | 股份 |
| Yu Fan | $5670000 | 1500000 | 1.73% | 股份 |
| NEA Management Company, LLC | $5528575 | 1462586 | 1.68% | 股份 |
| STEMPOINT CAPITAL LP | $5391490 | 1426320 | 1.64% | 股份 |
| Propel Bio Management, LLC | $4842981 | 1281212 | 1.47% | 股份 |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $4800600 | 1270000 | 1.46% | 股份 |
| JPMORGAN CHASE & CO | $4647305 | 1309100 | 1.41% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4233600 | 1120000 | 1.29% | 股份 |
| Ikarian Capital, LLC | $4152521 | 1129101 | 1.26% | 股份 |
| Polar Capital Holdings Plc | $4060529 | 1074214 | 1.24% | 股份 |
| MARSHALL WACE, LLP | $3651131 | 965907 | 1.11% | 股份 |
| Alyeska Investment Group, L.P. | $3436020 | 909000 | 1.05% | 股份 |
| MORGAN STANLEY | $3408199 | 901640 | 1.04% | 股份 |
| JANE STREET GROUP, LLC | $3407175 | 901369 | 1.04% | 股份 |
| HighVista Strategies LLC | $3142851 | 831442 | 0.96% | 股份 |
| Deep Track Capital, LP | $3024000 | 800000 | 0.92% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $2752260 | 728111 | 0.84% | 股份 |
| DIADEMA PARTNERS LP | $2725718 | 740786 | 0.83% | 股份 |
| BVF INC/IL | $2593231 | 686040 | 0.79% | 股份 |
| FMR LLC | $2590812 | 685400 | 0.79% | 股份 |
| Ally Bridge Group (NY) LLC | $2399544 | 634800 | 0.73% | 股份 |
| Qube Research & Technologies Ltd | $1502769 | 397558 | 0.46% | 股份 |
| J. Goldman & Co LP | $1275750 | 337500 | 0.39% | 股份 |
| Simplify Asset Management Inc. | $1184966 | 313483 | 0.36% | 股份 |
| Artisan Partners Limited Partnership | $996174 | 263538 | 0.30% | 股份 |
| Ghisallo Capital Management LLC | $945000 | 250000 | 0.29% | 股份 |
| Burkehill Global Management, LP | $850500 | 225000 | 0.26% | 股份 |
| SEVEN GRAND MANAGERS, LLC | $850500 | 225000 | 0.26% | 股份 |
| GOLDMAN SACHS GROUP INC | $848606 | 224499 | 0.26% | 股份 |
| XTX Topco Ltd | $809986 | 214282 | 0.25% | 股份 |
| Persistent Asset Partners Ltd | $790708 | 209182 | 0.24% | 股份 |
| Quadrature Capital Ltd | $783148 | 207182 | 0.24% | 股份 |
| Seven Fleet Capital Management LP | $756533 | 200141 | 0.23% | 股份 |
| BANK OF AMERICA CORP /DE/ | $574247 | 151917 | 0.17% | 股份 |
| Balyasny Asset Management L.P. | $545004 | 144181 | 0.17% | 股份 |
| Walleye Capital LLC | $512749 | 135648 | 0.16% | 股份 |
| Hudson Bay Capital Management LP | $434700 | 115000 | 0.13% | 股份 |
| Rathbones Group PLC | $378000 | 100000 | 0.12% | 股份 |
| COMMONWEALTH EQUITY SERVICES, LLC | $317500 | 83996 | 0.10% | 股份 |
| Engineers Gate Manager LP | $268818 | 71116 | 0.08% | 股份 |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $157922 | 36726 | 0.05% | 股份 |
| Jefferies Financial Group Inc. | $151200 | 40000 | 0.05% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $129861 | 34355 | 0.04% | 股份 |
| R Squared Ltd | $113090 | 29918 | 0.03% | 股份 |
| Quaker Wealth Management, LLC | $94349 | 24960 | 0.03% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $92485 | 24467 | 0.03% | 股份 |
| Shay Capital LLC | $82672 | 21871 | 0.03% | 股份 |
| China Universal Asset Management Co., Ltd. | $81648 | 21600 | 0.02% | 股份 |
| NewEdge Advisors, LLC | $75895 | 20078 | 0.02% | 股份 |
| Cerity Partners LLC | $75600 | 20000 | 0.02% | 股份 |
| ROYAL BANK OF CANADA | $60000 | 15741 | 0.02% | 股份 |
| Ground Swell Capital, LLC | $48395 | 12803 | 0.01% | 股份 |
| BLAIR WILLIAM & CO/IL | $37800 | 10000 | 0.01% | 股份 |
| Frec Markets, Inc. | $37800 | 10000 | 0.01% | 股份 |
| CITIGROUP INC | $24993 | 6612 | 0.01% | 股份 |
| GAMMA Investing LLC | $18976 | 5020 | 0.01% | 股份 |
| RHUMBLINE ADVISERS | $17656 | 4672 | 0.01% | 股份 |
| Tower Research Capital LLC (TRC) | $6804 | 1800 | 0.00% | 股份 |
| BARCLAYS PLC | $6732 | 1781 | 0.00% | 股份 |
| Stone House Investment Management, LLC | $5530 | 1463 | 0.00% | 股份 |
| SYQUANT CAPITAL SAS | $3452 | 913135 | 0.00% | 股份 |
| OSAIC HOLDINGS, INC. | $1164 | 308 | 0.00% | 股份 |
| Atlantic Union Bankshares Corp | $1134 | 300 | 0.00% | 股份 |
| Larson Financial Group LLC | $851 | 225 | 0.00% | 股份 |
| Caitong International Asset Management Co., Ltd | $586 | 155 | 0.00% | 股份 |
| HRT FINANCIAL LP | $468 | 123953 | 0.00% | 股份 |
| Bell Investment Advisors, Inc | $288 | 76 | 0.00% | 股份 |
| Arax Advisory Partners | $193 | 51 | 0.00% | 股份 |
| Covestor Ltd | $2 | 402 | 0.00% | 股份 |