OKUR OnKure Therapeutics, Inc. - Class A Common Stock
$4.35
价格 · 八月 19, 2026
截至...的财报数据 八月 4, 2026
52周区间
$2–$5
66% of range
分析师评级
BUY
12 analysts
目标价
$16
+256% upside
P/E (TTM)
-0.7
ROE
-88.6%
净利润率
-1733.7%
OKUR 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围
价格
$4.35
市值
—
P/E (TTM)
-0.7
每股收益 (TTM)
$-4.40
营收 (TTM)
$0
股息收益率
—
ROE
-88.6%
负债/权益
—
52周区间
$2 – $5
OKUR 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图
Configure
10年表现 收入、净利润、利润率和每股收益趋势
营收与净利润
$0
2024-12-31
→
2024-12-31
EPS
$-4.40
2020-12-31
→
2025-12-31
自由现金流
$-52M
2021-12-31
→
2025-12-31
利润率
-1733.7%
估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜？
指标
5年趋势
OKUR
同行中位数
P/E (TTM)
-0.7
1.2
盈利能力 毛利率、营业利润率和净利率；股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)
指标
5年趋势
OKUR
同行中位数
Operating Margin (营业利润率)
-1833.7%
—
Net Profit Margin (净利润率)
-1733.7%
-1189.1%
ROA
-67.2%
-58.9%
ROE
-88.6%
-79.0%
财务健康 债务、流动性、偿付能力 — 资产负债表强度
指标
5年趋势
OKUR
同行中位数
Current Ratio (流动比率)
10.3
5.4
Quick Ratio (速动比率)
10.0
—
成长 营收、每股收益 (EPS) 和净利润增长：同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)
指标
5年趋势
OKUR
同行中位数
资本效率 资产周转率、库存周转率、应收账款周转率
指标
5年趋势
OKUR
同行中位数
OKUR 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间
买入
12 位分析师
- 强烈买入 4 33.3%
- 买入 6 50.0%
- 持有 2 16.7%
- 卖出 0 0.0%
- 强烈卖出 0 0.0%
12个月价格目标
4 位分析师 · 2026-08-18
中位数
$15.00
← 低于所有目标
$4.35
最低
$11.00
最高
$21.00
中位数目标
$15.00
+244.8%
平均目标
$15.50
+256.3%
收益历史 每股收益实际值 vs 预估值，惊喜%，达标率，下次财报日期
平均惊喜
0.11%
| 期间 | EPS Actual | EPS 预期 | 惊喜 |
|---|---|---|---|
| 2026年6月30日 | $-0.31 | $-0.55 | 0.24% |
| 2026年3月31日 | $-1.11 | $-0.76 | -0.35% |
| 2025年12月31日 | $-0.99 | $-1.18 | 0.18% |
| 2025年9月30日 | $-1.09 | $-1.22 | 0.13% |
| 2025年6月30日 | $-1.14 | $-1.27 | 0.13% |
| 2025年3月31日 | $-1.19 | $-1.49 | 0.30% |
同行比较（GICS 子行业） 关键指标与行业同行对比
| 股票代码 | 市值 | P/E | 营收同比增长 | 净利润率 | ROE | 毛利率 |
|---|---|---|---|---|---|---|
| OKUR | — | -0.7 | — | -1733.7% | -88.6% | — |
| VYGR | $232M | -1.9 | -49.5% | -296.5% | -54.4% | — |
| NKTX | $131M | -1.3 | — | — | -31.1% | — |
| CRBU | $151M | -1.0 | 11.7% | -1327.4% | -102.8% | — |
| CNTN | $112M | -2.7 | — | — | -18.0% | — |
| TNYA | $154M | -1.2 | — | — | -81.2% | — |
| UNCY | $128M | -3.5 | -29.0% | — | -113.9% | — |
| CNTB | $159M | -2.8 | -99.8% | -86687.5% | -97.9% | — |
| SPRB | $120M | -1.7 | -51.3% | — | -139.9% | — |
| EQ | $95M | -4.0 | 13.9% | — | -133.1% | — |
完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表
损益表 13
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| Revenue | · | $0 | |
| R&D Expense | $48M | $44M | |
| SG&A Expense | $15M | $11M | |
| Operating Expenses | $63M | $54M | |
| Operating Income | $-63M | $-54M | |
| Interest Income | $3M | $2M | |
| Income Tax | $0 | $0 | |
| Net Income | $-60M | $-53M | |
| EPS (Basic) | $-4.40 | $-15.28 | |
| EPS (Diluted) | $-4.40 | $-15.28 | |
| Shares (Basic) | 13,515,915 | 3,447,071 | |
| Shares (Diluted) | 13,515,915 | 3,447,071 | |
| EBITDA | $-63M | $-54M |
资产负债表 19
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| Cash & Equivalents | $59M | $111M | |
| Prepaid Expense | $2M | $2M | |
| Current Assets | $61M | $113M | |
| PP&E (Net) | $618.0K | $1M | |
| PP&E (Gross) | $2M | $2M | |
| Accum. Depreciation | $1M | $1M | |
| Other Non-current Assets | $273.0K | $109.0K | |
| Total Assets | $62M | $115M | |
| Accounts Payable | $1M | $3M | |
| Accrued Liabilities | · | $7M | |
| Current Liabilities | $6M | $11M | |
| Capital Leases | $0 | $549.0K | |
| Other Non-current Liabilities | $12.0K | · | |
| Total Liabilities | $6M | $11M | |
| Paid-in Capital | $270M | $259M | |
| Retained Earnings | $-214M | $-155M | |
| AOCI | $0 | · | |
| Stockholders' Equity | $56M | $104M | |
| Liabilities + Equity | $62M | $115M |
现金流 9
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| D&A | $447.0K | $459.0K | |
| Stock-based Comp | $12M | $5M | |
| Other Non-cash | $-4M | $-3M | |
| Operating Cash Flow | $-52M | $-51M | |
| CapEx | $46.0K | $52.0K | |
| Investing Cash Flow | $-46.0K | $16M | |
| Financing Cash Flow | $163.0K | $116M | |
| Net Change in Cash | $-52M | $81M | |
| Free Cash Flow | $-52M | $-51M |
盈利能力 5
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| Operating Margin | -1833.7% | · | |
| Net Margin | -1733.7% | · | |
| EBITDA Margin | -1820.6% | · | |
| ROA | -67.2% | -69.9% | |
| ROE | -88.6% | 337.4% |
流动性与偿付能力 2
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| Current Ratio | 10.3 | 10.7 | |
| Quick Ratio | 10.0 | 10.5 |
效率 1
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 |
估值 (TTM) 4
| 指标 | 趋势 | 2025 | 2024 |
|---|---|---|---|
| Revenue TTM | · | $0 | |
| Net Income TTM | $-60M | $-53M | |
| P/E | -0.7 | -0.6 | |
| Earnings Yield | -151.7% | -177.7% |
损益表 12
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $13M | $12M | $11M | $12M | $13M | $13M | $14M | $10M | $11M | $9M | $-7M | $14M | $14M | $11M | $10M | $10M | |
| SG&A Expense | $4M | $4M | $3M | $4M | $4M | $4M | $4M | $1M | $4M | $1M | $-14M | $7M | $7M | $5M | $4M | $4M | |
| Operating Expenses | $17M | $16M | $14M | $16M | $16M | $17M | $19M | $12M | $14M | $10M | $-21M | $21M | $21M | $16M | $15M | $14M | |
| Operating Income | $-17M | $-16M | $-14M | $-16M | $-16M | $-17M | $-19M | $-12M | $-14M | $-10M | $21M | $-21M | $-21M | $-16M | $-15M | $-14M | |
| Interest Income | $2M | $458.0K | $628.0K | $804.0K | $934.0K | $1M | $1M | $174.0K | $230.0K | $295.0K | · | · | · | · | · | · | |
| Other Non-op | · | · | · | · | · | · | · | $972.0K | $1M | $1M | · | $2M | $2M | $1M | $962.0K | $833.0K | |
| Net Income | $-15M | $-15M | $-14M | $-15M | $-15M | $-16M | $-17M | $-12M | $-14M | $-10M | $19M | $-19M | $-20M | $-15M | $-14M | $-13M | |
| EPS (Basic) | $-0.31 | $-1.11 | $-0.98 | $-1.09 | $-1.14 | $-1.19 | $96.46 | $-36.55 | $-44.82 | $-30.37 | $-117.48 | $-5.68 | $-0.65 | $-0.60 | $-0.56 | $-0.53 | |
| EPS (Diluted) | $-0.31 | $-1.11 | $-0.98 | $-1.09 | $-1.14 | $-1.19 | $96.46 | $-36.55 | $-44.82 | $-30.37 | $-117.48 | $-5.68 | $-0.65 | $-0.60 | $-0.56 | $-0.53 | |
| Shares (Basic) | 49,869,177 | 13,674,577 | -26,948,392 | 13,530,892 | 13,509,080 | 13,424,335 | 2,501,435 | 316,142 | 315,478 | 314,016 | -58,348,708 | 3,380,794 | 30,215,321 | 25,036,410 | -48,922,002 | 24,496,313 | |
| Shares (Diluted) | 49,869,177 | 13,674,577 | -26,948,392 | 13,530,892 | 13,509,080 | 13,424,335 | 2,501,435 | 316,142 | 315,478 | 314,016 | -58,348,708 | 3,380,794 | 30,215,321 | 25,036,410 | -48,922,002 | 24,496,313 | |
| EBITDA | $-17M | $-16M | · | $-15M | $-16M | $-17M | · | $-5M | $-6M | $-10M | · | $-21M | $-21M | $-16M | · | $-14M |
资产负债表 22
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $167M | $192M | $59M | $70M | $83M | $97M | $111M | $61M | $36M | $20M | $30M | $12M | $9M | $30M | $20M | $62M | |
| Short-term Investments | · | · | · | · | · | · | · | $16M | $41M | $62M | · | $114M | $134M | $63M | $81M | $54M | |
| Prepaid Expense | $1M | $5M | $2M | $1M | $1M | $2M | $2M | $331.0K | $1M | $1M | $4M | $3M | $4M | $3M | $5M | $5M | |
| Current Assets | $178M | $197M | $61M | $72M | $85M | $98M | $113M | $77M | $78M | $84M | $34M | $129M | $146M | $97M | $106M | $121M | |
| PP&E (Net) | $435.0K | $519.0K | $618.0K | $720.0K | $821.0K | $925.0K | $1M | $59.0K | $81.0K | $102.0K | $1M | $529.0K | $554.0K | $581.0K | $453.0K | $241.0K | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | · | $2M | · | · | · | $555.0K | · | |
| Accum. Depreciation | $2M | $2M | $1M | $1M | $1M | $1M | $1M | · | · | · | $665.0K | · | · | · | $102.0K | · | |
| Other Non-current Assets | $401.0K | $405.0K | $273.0K | $104.0K | $116.0K | $109.0K | $109.0K | $147.0K | $153.0K | $64.0K | $58.0K | $81.0K | $79.0K | $81.0K | $84.0K | $79.0K | |
| Total Assets | $179M | $199M | $62M | $73M | $86M | $100M | $115M | $78M | $79M | $85M | $36M | $130M | $148M | $99M | $108M | $123M | |
| Accounts Payable | $2M | $11M | $1M | $1M | $2M | $2M | $3M | $237.0K | $64.0K | $676.0K | $3M | $2M | $2M | $2M | $2M | $2M | |
| Accrued Liabilities | · | · | · | · | $5M | $6M | · | $725.0K | $953.0K | $2M | $4M | $11M | $12M | $8M | $5M | $7M | |
| Current Liabilities | $7M | $14M | $6M | $6M | $8M | $9M | $11M | $3M | $1M | $3M | $7M | $14M | $14M | $10M | $7M | $9M | |
| Capital Leases | $590.0K | $0 | · | $120.0K | $267.0K | $409.0K | $549.0K | $379.0K | $492.0K | $576.0K | $466.0K | $812.0K | $897.0K | $979.0K | $1M | $943.0K | |
| Other Non-current Liabilities | $12.0K | $12.0K | $12.0K | $40.0K | $40.0K | $40.0K | · | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $7M | $14M | $6M | $6M | $8M | $9M | $11M | $4M | $2M | $3M | $8M | $15M | $16M | $12M | $8M | $10M | |
| Common Stock | · | · | · | · | · | · | · | $0 | $3.0K | $3.0K | · | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $417M | $414M | $270M | $267M | $264M | $261M | $259M | $310M | $309M | $308M | $209.0K | $305M | $304M | $239M | $237M | $235M | |
| Retained Earnings | $-245M | $-229M | $-214M | $-201M | $-186M | $-171M | $-155M | $-236M | $-232M | $-227M | $-102M | $-191M | $-171M | $-152M | $-137M | $-123M | |
| AOCI | $-13.0K | · | · | · | · | · | · | $2.0K | $-13.0K | $-12.0K | · | $-21.0K | $-31.0K | $12.0K | $-43.0K | $-26.0K | |
| Stockholders' Equity | $172M | $184M | $56M | $66M | $78M | $91M | $104M | $74M | $77M | $81M | $-102M | $115M | $133M | $87M | $100M | $112M | |
| Liabilities + Equity | $179M | $199M | $62M | $73M | $86M | $100M | $115M | $78M | $79M | $85M | $36M | $130M | $148M | $99M | $108M | $123M | |
| Shares Outstanding | · | · | · | · | · | · | · | 3,343,525 | 33,420,808 | 33,420,808 | · | 33,872,166 | 33,800,788 | 25,107,430 | 24,699,553 | 24,529,646 |
现金流 11
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $87.0K | $104.0K | $104.0K | $108.0K | $117.0K | $118.0K | $116.0K | $114.0K | $115.0K | $114.0K | $291.0K | $43.0K | $42.0K | $41.0K | $25.0K | $22.0K | |
| Stock-based Comp | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $-70.0K | $842.0K | $107.0K | $-4M | $1M | $1M | $1M | $1M | $990.0K | |
| Other Non-cash | · | $-665.0K | · | · | · | $-943.0K | · | · | · | $-14M | · | · | · | $5M | · | · | |
| Operating Cash Flow | $-10M | $-13M | $-12M | $-13M | $-13M | $-14M | $-23M | $58.0K | $4M | $-11M | $9M | $-19M | $-16M | $-9M | $-16M | $-11M | |
| CapEx | $3.0K | $5.0K | $9.0K | $6.0K | $13.0K | $18.0K | $15.0K | $35.0K | $10.0K | $9.0K | $50.0K | $19.0K | $5.0K | $172.0K | $250.0K | $28.0K | |
| Investing Cash Flow | $-10M | $-5.0K | $-9.0K | $-6.0K | $-13.0K | $-18.0K | $16M | $-36M | $-14M | $-9.0K | $29M | $21M | $-69M | $19M | $-27M | $-45M | |
| Stock Issued | · | · | · | · | · | · | · | · | · | · | · | · | · | $1M | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $1M | · | · | |
| Financing Cash Flow | $-5M | $146M | $240.0K | $0 | $0 | $-77.0K | $110M | $6M | $6M | $10.0K | $-12M | $173.0K | $64M | $1M | $325.0K | $97.0K | |
| Net Change in Cash | $-26M | $133M | $-11M | $-13M | $-13M | $-14M | $103M | $-30M | $-4M | $-11M | $27M | $3M | $-21M | $10M | $-42M | $-56M | |
| Free Cash Flow | · | $-13M | · | · | · | $-14M | · | · | · | · | · | · | · | $-9M | · | · |
盈利能力 5
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1088.2% | -3409.4% | · | -1932.8% | -1747.8% | · | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -988.2% | -3309.4% | · | -1832.8% | -1647.8% | · | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -1088.2% | -3386.7% | · | -1919.3% | -1735.2% | · | · | · | · | · | · | · | · | · | · | · | |
| ROA | -11.6% | -10.2% | · | -19.5% | -18.7% | -17.3% | · | -3.5% | -4.7% | -9.2% | · | -15.2% | -13.9% | -12.4% | · | -9.1% | |
| ROE | -12.3% | -11.0% | · | -20.9% | -19.9% | -18.5% | · | -3.9% | -5.1% | -10.0% | · | -16.9% | -15.2% | -13.6% | · | -9.7% |
流动性与偿付能力 2
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 26.7 | 13.8 | · | 11.4 | 11.1 | 11.2 | · | 23.7 | 57.9 | 29.8 | · | 9.5 | 10.7 | 9.3 | · | 12.8 | |
| Quick Ratio | 25.1 | 13.4 | · | 11.3 | 11.0 | 11.0 | · | 23.6 | 56.9 | 29.4 | · | 9.3 | 10.4 | 8.9 | · | 12.3 |
效率 1
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | · | · | · | · | · | · | · | · | · | · | · |
估值 (TTM) 8
| 指标 | 趋势 | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-59M | $-59M | · | $-63M | $-60M | $-59M | · | $-54M | $-62M | $-63M | · | $-67M | $-60M | $-53M | · | $-51M | |
| Market Cap | · | · | · | · | · | · | · | $57M | $505M | $555M | · | $2.58B | $2.22B | $1.50B | · | $822M | |
| P/E | -1.2 | -0.9 | · | -0.1 | -0.0 | -0.0 | · | -0.1 | -0.2 | -0.4 | · | -10.2 | -28.8 | -27.7 | · | -16.1 | |
| P/B | · | · | · | · | · | · | · | 0.8 | 6.6 | 6.8 | · | 22.4 | 16.7 | 17.2 | · | 7.3 | |
| P / Tangible Book | · | · | · | · | · | · | · | 0.8 | 6.6 | 6.8 | · | 22.4 | 16.7 | 17.2 | · | 7.3 | |
| P / Cash Flow | · | · | · | · | · | · | · | · | · | -26.4 | · | · | · | -165.9 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -162.8 | · | · | |
| Earnings Yield | -80.0% | -109.4% | · | -1453.5% | -3502.1% | -2626.3% | · | -690.7% | -539.9% | -224.7% | · | -9.8% | -3.5% | -3.6% | · | -6.2% |
财务报表 损益表、资产负债表、现金流量表 — 年度，近5年
损益表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 收入 | — | $0 | — | — | — |
| 营业利润率 % | -1833.7% | — | — | — | — |
| 净收入 | $-60M | $-53M | $-35M | $-52M | $-40M |
| 稀释后每股收益 (EPS) | $-4.40 | $-15.28 | $-124.41 | $-2.12 | $-2.19 |
资产负债表
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 流动比率 | 10.3 | 10.7 | — | 14.9 | 24.8 |
| 速动比率 | 10.0 | 10.5 | — | 14.2 | 23.8 |
现金流
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| 自由现金流 | $-52M | $-51M | — | $-48M | $-38M |
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机构持有人 (13F) 78 家申报者 · $148.9M 总计 · 截至 2026年6月30日
在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸；单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存，而非方向性判断。
机构活动 — Q2 2026 与上一季度对比
| 新仓位 | 已退出持仓 | 增加 | 减少 | 净股数变动 |
|---|---|---|---|---|
| 34 (+16 与上一季度对比) | 8 (+1 与上一季度对比) | 14 (+1 与上一季度对比) | 13 (+1 与上一季度对比) | +2.7M |
与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天，外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过，优先显示最近一个已完整报告的季度对。
| 机构 | 价值 | 股份 | % 已追踪的13F | 类型 |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $18232398 | 3998333 | 12.25% | 股份 |
| BVF INC/IL | $14755148 | 3235778 | 9.91% | 股份 |
| ACORN CAPITAL ADVISORS, LLC | $12948913 | 2839674 | 8.70% | 股份 |
| StepStone Group LP | $11014934 | 2660612 | 7.40% | 股份 |
| ADAR1 Capital Management, LLC | $10208399 | 2238684 | 6.86% | 股份 |
| Vivo Capital, LLC | $8790358 | 1927710 | 5.91% | 股份 |
| Vestal Point Capital, LP | $8325187 | 1825699 | 5.59% | 股份 |
| Trails Edge Capital Partners, LP | $6559359 | 1438456 | 4.41% | 股份 |
| VANGUARD CAPITAL MANAGEMENT LLC | $6552898 | 1437039 | 4.40% | 股份 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5493975 | 1204819 | 3.69% | 股份 |
| CITADEL ADVISORS LLC | $5412934 | 1187047 | 3.64% | 股份 |
| Sio Capital Management, LLC | $4920080 | 1078965 | 3.31% | 股份 |
| Prosight Management, LP | $4464204 | 978992 | 3.00% | 股份 |
| Logos Global Management LP | $4395179 | 963855 | 2.95% | 股份 |
| GEODE CAPITAL MANAGEMENT, LLC | $2788902 | 611596 | 1.87% | 股份 |
| NEA Management Company, LLC | $2182179 | 478548 | 1.47% | 股份 |
| STATE STREET CORP | $2114299 | 463662 | 1.42% | 股份 |
| Ensign Peak Advisors, Inc | $1968237 | 431631 | 1.32% | 股份 |
| RENAISSANCE TECHNOLOGIES LLC | $1635845 | 358738 | 1.10% | 股份 |
| Sofinnova Investments, Inc. | $1466916 | 321692 | 0.99% | 股份 |
| Carlyle Group Inc. | $1230721 | 269895 | 0.83% | 股份 |
| Seven Fleet Capital Management LP | $1098791 | 240963 | 0.74% | 股份 |
| Affinity Asset Advisors, LLC | $1098791 | 240963 | 0.74% | 股份 |
| DV EQUITIES, LLC | $1098791 | 240963 | 0.74% | 股份 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $810613 | 177766 | 0.54% | 股份 |
| VANGUARD FIDUCIARY TRUST CO | $753207 | 165177 | 0.51% | 股份 |
| Rosalind Advisors, Inc. | $684000 | 150000 | 0.46% | 股份 |
| Stonepine Capital Management, LLC | $595919 | 130684 | 0.40% | 股份 |
| KOTLER KEVIN | $573304 | 197691 | 0.39% | 股份 |
| Longaeva Partners L.P. | $549398 | 120482 | 0.37% | 股份 |
| TWO SIGMA INVESTMENTS, LP | $496447 | 108870 | 0.33% | 股份 |
| BANK OF AMERICA CORP /DE/ | $484819 | 106320 | 0.33% | 股份 |
| CANTOR FITZGERALD, L. P. | $456064 | 100014 | 0.31% | 股份 |
| UBS Group AG | $454194 | 99604 | 0.31% | 股份 |
| Rangeley Capital, LLC | $433200 | 95000 | 0.29% | 股份 |
| Aisling Capital Management LP | $404048 | 88607 | 0.27% | 股份 |
| Walleye Capital LLC | $324230 | 71103 | 0.22% | 股份 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $290198 | 63640 | 0.19% | 股份 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $229336 | 50293 | 0.15% | 股份 |
| Shay Capital LLC | $228000 | 50000 | 0.15% | 股份 |
| DIMENSIONAL FUND ADVISORS LP | $221766 | 48633 | 0.15% | 股份 |
| PRELUDE CAPITAL MANAGEMENT, LLC | $212916 | 46692 | 0.14% | 股份 |
| Aldebaran Capital, LLC | $181803 | 39869 | 0.12% | 股份 |
| Nuveen, LLC | $161433 | 35402 | 0.11% | 股份 |
| Verdad Advisers, LP | $130690 | 28660 | 0.09% | 股份 |
| Bank of New York Mellon Corp | $119705 | 26251 | 0.08% | 股份 |
| DEUTSCHE BANK AG\ | $116572 | 25564 | 0.08% | 股份 |
| AMERICAN CENTURY COMPANIES INC | $105231 | 23077 | 0.07% | 股份 |
| WELLS FARGO & COMPANY/MN | $100097 | 21951 | 0.07% | 股份 |
| RHUMBLINE ADVISERS | $95736 | 20996 | 0.06% | 股份 |
| Jump Financial, LLC | $93024 | 20400 | 0.06% | 股份 |
| BNP PARIBAS FINANCIAL MARKETS | $90694 | 19889 | 0.06% | 股份 |
| MARSHALL WACE, LLP | $83744 | 18365 | 0.06% | 股份 |
| NEW YORK STATE COMMON RETIREMENT FUND | $82536 | 18100 | 0.06% | 股份 |
| XTX Topco Ltd | $77383 | 16970 | 0.05% | 股份 |
| TWO SIGMA ADVISERS, LP | $77163 | 26608 | 0.05% | 股份 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $55035 | 12069 | 0.04% | 股份 |
| Y-Intercept (Hong Kong) Ltd | $51473 | 11288 | 0.03% | 股份 |
| CITIGROUP INC | $48687 | 10677 | 0.03% | 股份 |
| Invesco Ltd. | $47657 | 10451 | 0.03% | 股份 |
| Police & Firemen's Retirement System of New Jersey | $47073 | 10323 | 0.03% | 股份 |
| MORGAN STANLEY | $29900 | 6557 | 0.02% | 股份 |
| BARCLAYS PLC | $20520 | 4500 | 0.01% | 股份 |
| NORTHERN TRUST CORP | $18778 | 4118 | 0.01% | 股份 |
| Legal & General Group Plc | $11651 | 2555 | 0.01% | 股份 |
| Ameritas Investment Partners, Inc. | $10848 | 2379 | 0.01% | 股份 |
| Russell Investments Group, Ltd. | $9557 | 2096 | 0.01% | 股份 |
| Tower Research Capital LLC (TRC) | $7346 | 1611 | 0.00% | 股份 |
| BlackRock, Inc. | $6644 | 1457 | 0.00% | 股份 |
| ROYAL BANK OF CANADA | $4000 | 966 | 0.00% | 股份 |
| Sterling Capital Management LLC | $2408 | 528 | 0.00% | 股份 |
| VANGUARD GROUP INC | $2161 | 745 | 0.00% | 股份 |
| TRUST CO OF TOLEDO NA /OH/ | $620 | 136 | 0.00% | 股份 |
| OSAIC HOLDINGS, INC. | $410 | 90 | 0.00% | 股份 |
| FMR LLC | $406 | 89 | 0.00% | 股份 |
| JPMORGAN CHASE & CO | $203 | 45 | 0.00% | 股份 |
| PRICE T ROWE ASSOCIATES INC /MD/ | $98 | 21481 | 0.00% | 股份 |
| T. Rowe Price Investment Management, Inc. | $70 | 15335 | 0.00% | 股份 |
公司内部人士 28 位内幕人士 · 6 位高管 · 9 位董事
| 内部人士 | 角色 | 上次活动 | 持股数量 | 买入 12个月 | 卖出 12个月 | 净额 12个月 |
|---|---|---|---|---|---|---|
| Gregory J. Flesher | President and CEO | 2022年12月9日 A | 109600 | 0 | 0 | $0 |
| Michael Cruse | Chief Operating Officer | 2022年12月9日 A | 13697 | 0 | 0 | $0 |
| Ashley Hall | Chief Development Officer | 2023年8月28日 M | 39600 | 0 | 0 | $0 |
| Jennifer Lam | VP of Finance & Administration | 2022年12月9日 A | — | 0 | 0 | $0 |
| Alejandro Dorenbaum | Chief Medical Officer | 2022年12月9日 A | 30000 | 0 | 0 | $0 |
| Wendy S. Johnson | Chief Development Officer | 2021年7月14日 S | 0 | 0 | 0 | $0 |
| Roshawn A. Blunt | 董事 | 2023年6月6日 A | — | 0 | 0 | $0 |
| Bali Muralidhar | 董事 | 2023年6月6日 A | 2073957 | 0 | 0 | $0 |
| Niall O'Donnell, Ph.D. | 董事 | 2023年6月6日 A | 2188713 | 0 | 0 | $0 |
| Eric M Dube | 董事 | 2023年6月6日 A | — | 0 | 0 | $0 |
| Stacey Denenberg Seltzer | 董事 | 2023年6月6日 A | — | 0 | 0 | $0 |
| Paul W. Hoelscher | 董事 | 2023年6月6日 A | — | 0 | 0 | $0 |
| Lon Cardon | 董事 | 2021年4月8日 A | — | 0 | 0 | $0 |
| Kenneth Harrison Ph.D. | 董事 | 2021年4月8日 A | — | 0 | 0 | $0 |
| Novo Holdings A/S | 10% 所有者 | 2023年6月23日 S | 3330337 | 0 | 0 | $0 |
| Dylan Hartley | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Andrew John Phillips | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Valerie Malyvanh Jansen | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Samuel Agresta | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Jason A. Leverone | — | 2026年8月7日 A | 18802 | 0 | 1 | $-1333 |
| Michael R Carruthers | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Isaac Manke | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Nicholas A Saccomano | — | 2026年8月7日 A | 11247 | 0 | 1 | $-378 |
| Liam Ratcliffe | — | 2026年8月7日 A | — | 0 | 0 | $0 |
| Edward T. Mathers | — | 2026年8月7日 A | 15310 | 0 | 0 | $0 |
| Michael G Grey | — | 2026年8月7日 A | 0 | 0 | 0 | $0 |
| Leonard Braden Michael | — | 2024年10月7日 J | 102076 | 0 | 0 | $0 |
| Vineet R. Jindal | — | 2021年12月10日 A | 36600 | 0 | 0 | $0 |
来自SEC表格3/4/5申报的内部人士；净额=仅公开市场买卖
激进投资者及 5%+ 股东 10 持仓
提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权，意图影响发行人（激进股东持股、董事会活动、并购）。每一行显示该申报人持仓的最新已知状态。
| 申报人 | 已申报 | 持股 | 状态 | 目的 | 申报 |
|---|---|---|---|---|---|
| AI Biotechnology LLC, Access Industries Holdings LLC, Access Industries Management, LLC, Len Blavatnik | 2026年4月7日 | 19.99% | 初始申报 | 被动投资 | SEC |
| ACORN BIOVENTURES, L.P., ACORN CAPITAL ADVISORS GP, LLC, Anders Hove, ACORN BIOVENTURES 2, L.P., Acorn Capital Advisors GP 2, LLC ×2 申报 | 2025年5月30日 | 22.10% | 修订 | 并购/出售 | SEC |
| RiverVest Venture Fund III, L.P., RiverVest Venture Fund III (Ohio), L.P., RiverVest Venture Partners III (Ohio), LLC, RiverVest Venture Partners III, L.P., RiverVest Venture Partners III, LLC, RiverVest Venture Fund IV, L.P., RiverVest Venture Partners IV, L.P., RiverVest Venture Partners IV, LLC, John P. McKearn, Ph.D., Jay Schmelter, Thomas C. Melzer, Niall O'Donnell, Ph.D. | 2025年1月21日 | 1.55% | 修订 | — | SEC |
| 2024年10月8日 | — | 初始申报 | — | SEC | |
| New Enterprise Associates 15, L.P., NEA Partners 15, L.P., NEA 15 GP, LLC, Forest Baskett, Anthony A. Florence, Jr., Mohamad H. Makhzoumi, Scott D. Sandell ×2 申报 | 2024年5月8日 | — | 初始申报 | — | SEC |
| TANG CAPITAL PARTNERS, LP, TANG CAPITAL MANAGEMENT, LLC, KEVIN TANG, Concentra Biosciences, LLC | 2023年12月26日 | — | 初始申报 | 被动投资 | SEC |
| Novo Holdings A/S ×5 申报 | 2023年12月15日 | — | 初始申报 | — | SEC |
| 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人 | 2023年5月30日 | — | 初始申报 | — | SEC |
| Abingworth LLP, Abingworth Bioventures 8, LP | 2021年4月20日 | — | 初始申报 | 被动投资 | SEC |
| 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人, 未披露的报告人 | 2021年4月19日 | — | 初始申报 | 被动投资 | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF持仓 由 5 只交易所交易基金持有
权重仅反映直接股权持仓（N-PORT）；杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。