QURE uniQure N.V. - Ordinary Shares

NASDAQ · Biotechnology · 在 SEC EDGAR 上查看 ↗
$47.19
价格 · 八月 19, 2026
截至...的财报数据 七月 29, 2026

QURE 股票快照 价格、市值、P/E、EPS、ROE、负债/权益、52周范围

价格
$47.19
市值
$2.97B
P/E (TTM)
-13.8
每股收益 (TTM)
$-3.46
营收 (TTM)
$16M
股息收益率
ROE
-204.2%
负债/权益
0.2
52周区间
$9 – $72

QURE 股价图表 包含技术指标的日 OHLCV — 平移、缩放和自定义您的视图

10年表现 收入、净利润、利润率和每股收益趋势

营收与净利润 $16M
10-point trend, -35.9%
2016-12-31 2025-12-31
EPS $-3.46
7-point trend, -11.3%
2019-12-31 2025-12-31
自由现金流 $-178M
9-point trend, -103.9%
2016-12-31 2025-12-31
利润率 -1236.0%

估值 P/E、P/S、P/B、EV/EBITDA 比率 — 该股票是昂贵还是便宜?

指标
5年趋势
QURE
同行中位数
P/E (TTM)
5-point trend, -334.8%
-13.8
P/S (TTM) (市销率 (TTM))
5-point trend, +4956.7%
184.8
92.4
P/B (市净率)
5-point trend, +365.3%
15.0
5.8
EV / EBITDA (企业价值 / EBITDA)
5-point trend, -585.0%
-15.9
Price / FCF (股价/自由现金流)
5-point trend, -335.6%
-16.7

盈利能力 毛利率、营业利润率和净利率;股本回报率 (ROE)、资产回报率 (ROA)、投入资本回报率 (ROIC)

指标
5年趋势
QURE
同行中位数
Operating Margin (营业利润率)
5-point trend, -2042.3%
-1151.4%
Net Profit Margin (净利润率)
5-point trend, -2065.0%
-1236.0%
-905.7%
ROA
5-point trend, -150.2%
-28.8%
-27.1%
ROE
5-point trend, -467.5%
-204.2%
-58.4%
ROIC
5-point trend, -273.8%
-76.7%

财务健康 债务、流动性、偿付能力 — 资产负债表强度

指标
5年趋势
QURE
同行中位数
Debt / Equity (负债/股东权益比率)
5-point trend, +47.4%
0.2
28.9
Current Ratio (流动比率)
5-point trend, -39.0%
10.4
7.9
Quick Ratio (速动比率)
5-point trend, -91.6%
1.3

成长 营收、每股收益 (EPS) 和净利润增长:同比、3年复合年增长率 (CAGR)、5年复合年增长率 (CAGR)

指标
5年趋势
QURE
同行中位数
Revenue YoY (营收同比增长)
5-point trend, -96.9%
-40.6%
Revenue CAGR 3Y (营收3年复合年增长率)
5-point trend, -96.9%
-46.7%
Revenue CAGR 5Y (营收5年复合年增长率)
5-point trend, -96.9%
-15.6%

每股指标 每股收益 (EPS)、每股净资产、每股现金流、每股股息

指标
5年趋势
QURE
同行中位数
EPS (Diluted) (EPS (稀释))
5-point trend, -149.1%
$-3.46

资本效率 资产周转率、库存周转率、应收账款周转率

指标
5年趋势
QURE
同行中位数

QURE 分析师共识 看涨和看跌分析师观点、12个月价格目标、上涨空间

买入 20 位分析师
  • 强烈买入 7 35.0%
  • 买入 11 55.0%
  • 持有 2 10.0%
  • 卖出 0 0.0%
  • 强烈卖出 0 0.0%

12个月价格目标

11 位分析师 · 2026-08-15
中位数目标 $69.15 +46.5%
平均目标 $69.78 +47.9%

收益历史 每股收益实际值 vs 预估值,惊喜%,达标率,下次财报日期

平均惊喜
-0.01%
期间 EPS Actual EPS 预期 惊喜
2026年6月30日 $-1.22 $-0.84 -0.38%
2026年3月31日 $-0.85 $-0.89 0.04%
2025年12月31日 $-0.64 $-0.97 0.33%
2025年9月30日 $-1.38 $-0.92 -0.46%
2025年6月30日 $-0.69 $-0.91 0.22%
2025年3月31日 $-0.82 $-1.03 0.21%

同行比较(GICS 子行业) 关键指标与行业同行对比

股票代码 市值 P/E 营收同比增长 净利润率 ROE 毛利率
QURE $1.49B -6.9 -40.6% -1236.0% -204.2%
NAMS
PRQR

完整基本面 所有年度指标 — 损益表、资产负债表、现金流量表

损益表 17
QURE 的年度损益表数据
指标 趋势 20252024202320222021202020192018201720162015
Revenue 11-point trend, +52.2% $16M $27M $16M $106M $524M $38M $7M $11M $13M $25M $11M
Cost of Revenue 10-point trend, +25.1% $2M $1M $65.0K $1M $25M $3M $2M $1M $817.0K $1M ·
R&D Expense 11-point trend, +137.9% $141M $144M $215M $198M $144M $122M $95M $75M $72M $73M $59M
SG&A Expense 11-point trend, +179.9% $65M $53M $75M $55M $56M $43M $34M $25M $25M $26M $23M
Operating Expenses 11-point trend, +151.9% $208M $215M $303M $256M $225M $165M $128M $100M $97M $99M $83M
Operating Income 11-point trend, -160.5% $-185M $-184M $-283M $-143M $311M $-125M $-121M $-88M $-71M $-72M $-71M
Interest Expense 9-point trend, +1515.7% · · $42M $12M $7M $4M $4M $2M $2M $2M $3M
Interest Income 11-point trend, +13922.3% $17M $21M $20M $609.0K $162.0K $938.0K $4M $3M $117.0K $70.0K $121.0K
Other Non-op 9-point trend, +252.2% $11M · · $3M $-160.0K $483.0K $-3M $208.0K $-2M $785.0K $-7M
Pretax Income 11-point trend, -132.2% $-193M $-237M $-307M $-128M $333M $-141M $-124M $-83M $-79M $-72M $-83M
Income Tax 10-point trend, +577.6% $6M $2M $2M $-1M $3M $-16M · $231.0K $-199.0K $1M $-1M
Net Income 11-point trend, -142.4% $-199M $-240M $-308M $-127M $330M $-125M $-124M $-83M $-79M $-73M $-82M
EPS (Basic) 7-point trend, -11.3% $-3.46 $-4.92 $-6.47 $-2.71 $7.17 $-2.81 $-3.11 · · · ·
EPS (Diluted) 7-point trend, -11.3% $-3.46 $-4.92 $-6.47 $-2.71 $7.04 $-2.81 $-3.11 · · · ·
Shares (Basic) 7-point trend, +43.8% 57,502,068 48,649,129 47,670,986 46,735,045 45,986,467 44,466,365 39,999,450 · · · ·
Shares (Diluted) 7-point trend, +43.8% 57,502,068 48,649,129 47,670,986 46,735,045 46,840,972 44,466,365 39,999,450 · · · ·
EBITDA 9-point trend, -157.6% $-185M $-184M $-283M $-143M $311M $-125M $-121M · $-71M $-72M ·
资产负债表 29
QURE 的年度资产负债表数据
指标 趋势 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, -63.8% $80M $159M $241M $228M $556M $245M $378M $235M $159M $132M $222M
Receivables 3-point trend, +59.3% $6M · · · · $7M · · · $4M ·
Inventory 3-point trend, +2436.7% · · $12M $7M · · · · · · $474.0K
Prepaid Expense 11-point trend, +2871.9% $21M $9M $15M $12M $11M $4M $5M $1M $1M $996.0K $690.0K
Other Current Assets 6-point trend, +153.3% · · · · · $3M $748.0K $329.0K $687.0K $1M $1M
Current Assets 11-point trend, +187.6% $656M $390M $652M $477M $628M $259M $384M $237M $163M $144M $228M
PP&E (Net) 11-point trend, -46.9% $14M $20M $47M $51M $44M $32M $29M $29M $34M $36M $26M
PP&E (Gross) 11-point trend, +55.7% $58M $52M $102M $95M $80M $68M $57M $52M $51M $48M $37M
Accum. Depreciation 11-point trend, +299.9% $44M $32M $56M $44M $37M $35M $29M $23M $17M $12M $11M
Goodwill 11-point trend, +5171.3% $25M $22M $26M $26M $28M $542.0K $496.0K $506.0K $530.0K $465.0K $481.0K
Intangibles 11-point trend, +968.1% $73M $71M $60M $59M $63M $3M $5M $5M $10M $8M $7M
Other Non-current Assets 9-point trend, +347.4% $6M $1M $3M $6M $6M $3M · · $2M $2M $1M
Total Assets 11-point trend, +214.1% $825M $557M $832M $705M $809M $340M $449M $274M $210M $190M $263M
Accounts Payable 11-point trend, +27.4% $5M $7M $7M $11M $3M $4M $6M $4M $3M $6M $4M
Accrued Liabilities 8-point trend, +401.6% $41M $29M $31M $31M $28M $18M $12M $8M · · ·
Current Liabilities 11-point trend, +133.8% $63M $40M $74M $76M $37M $27M $32M $20M $19M $23M $27M
Capital Leases 7-point trend, -68.4% $10M $11M $28M $32M $29M $30M $31M · · · ·
Deferred Tax 5-point trend, -38.3% $8M $7M $8M $8M $13M · · · · · ·
Other Non-current Liabilities 11-point trend, +532.4% $4M $8M $4M $935.0K $4M $3M $534.0K $435.0K $614.0K $51.0K $578.0K
Total Liabilities 11-point trend, +364.6% $626M $563M $624M $229M $213M $96M $126M $94M $120M $127M $135M
Long-term Debt 11-point trend, +255.9% $72M $66M $148M $144M $136M $42M $47M $48M $24M $20M $20M
Total Debt 9-point trend, +145.6% $50M $51M $102M $103M $101M $36M $36M · $21M $20M ·
Common Stock 11-point trend, +139.2% $4M $3M $3M $3M $3M $3M $3M $2M $2M $2M $2M
Paid-in Capital 11-point trend, +247.1% $1.58B $1.17B $1.15B $1.11B $1.08B $1.02B $987M $720M $567M $465M $456M
Retained Earnings 11-point trend, -311.8% $-1.33B $-1.13B $-890M $-582M $-455M $-785M $-660M $-536M $-475M $-396M $-323M
AOCI 11-point trend, -752.7% $-58M $-53M $-54M $-58M $-29M $-10M $-7M $-7M $-4M $-7M $-7M
Stockholders' Equity 11-point trend, +55.5% $199M $-7M $208M $476M $596M $244M $323M $180M $89M $64M $128M
Liabilities + Equity 11-point trend, +214.1% $825M $557M $832M $705M $809M $340M $449M $274M $210M $190M $263M
Shares Outstanding 11-point trend, +156.2% 62,336,717 48,988,087 47,833,830 46,968,032 46,298,635 44,777,799 43,711,954 37,351,653 31,339,040 25,257,420 24,327,944
现金流 16
QURE 的年度现金流数据
指标 趋势 20252024202320222021202020192018201720162015
D&A 9-point trend, +95.7% $15M $13M $12M $9M $7M $11M $7M $12M $8M · ·
Stock-based Comp 11-point trend, +52.2% $18M $22M $35M $34M $26M $22M $18M $11M $10M $6M $12M
Deferred Tax 10-point trend, +234.7% $2M $2M $2M $-1M $3M $-16M · $209.0K $-209.0K $1M $-1M
Restructuring · · $3M · · · · · · · ·
Operating Cash Flow 11-point trend, -2483.0% $-178M $-183M $-146M $-145M $288M $-135M $-99M $-76M $-64M $-72M $7M
CapEx 11-point trend, -94.2% $439.0K $3M $7M $18M $17M $7M $6M $2M $4M $15M $8M
Investing Cash Flow 11-point trend, -3909.2% $-322M $163M $-206M $-183M $-67M $-9M $-7M $-4M $-6M $-17M $-8M
Debt Issued 2-point trend, +333.6% · · · · $64M · · $15M · · ·
Net Debt Issued 2-point trend, -182.8% · $-53M · · $64M · · · · · ·
Stock Issued 7-point trend, +978.5% · · · · $31M $7M $6M $5M $4M $3M $3M
Net Stock Activity 5-point trend, +7.9% · · · · $3M $7M $6M · $4M $3M ·
Financing Cash Flow 11-point trend, +158.5% $415M $-59M $363M $1M $95M $7M $249M $158M $90M $2M $161M
Net Change in Cash 11-point trend, -150.0% $-79M $-84M $13M $-328M $312M $-133M $143M $75M $28M $-89M $157M
Taxes Paid 3-point trend, +62750.0% $8M $21.0K $12.0K · · · · · · · ·
Free Cash Flow 9-point trend, -103.9% $-178M $-186M $-153M $-163M $271M $-142M $-104M · $-69M $-87M ·
Levered FCF 6-point trend, -117.3% · · $-195M $-174M $263M $-145M · · $-71M $-90M ·
盈利能力 7
QURE 的年度盈利能力数据
指标 趋势 20252024202320222021202020192018201720162015
Operating Margin 9-point trend, -301.7% -1151.4% -679.6% -1785.5% -134.4% 59.3% -334.3% -1663.8% · -544.3% -286.7% ·
Net Margin 8-point trend, -104.4% -1236.0% -883.4% -1947.1% -119.1% 62.9% -333.3% -1705.8% · -604.7% · ·
Pretax Margin 9-point trend, -317.3% -1201.0% -874.4% -1935.0% -120.4% 63.5% -377.0% -1705.8% · -606.2% -287.8% ·
EBITDA Margin 9-point trend, -301.7% -1151.4% -679.6% -1785.5% -134.4% 59.3% -334.3% -1663.8% · -544.3% -286.7% ·
ROA 8-point trend, +27.3% -28.8% -34.5% -40.2% -16.8% 57.3% -31.7% -34.4% · -39.6% · ·
ROE 8-point trend, -97.1% -204.2% -976.4% -129.5% -28.3% 55.6% -53.0% -36.9% · -103.6% · ·
ROIC 8-point trend, +12.0% -76.7% -417.7% -92.0% -24.4% 44.1% -39.7% · · -64.6% -87.2% ·
流动性与偿付能力 5
QURE 的年度流动性与偿付能力数据
指标 趋势 20252024202320222021202020192018201720162015
Current Ratio 9-point trend, +64.6% 10.4 9.7 8.8 6.3 17.1 9.5 12.1 · 8.5 6.3 ·
Quick Ratio 9-point trend, -78.7% 1.3 4.0 3.3 3.0 15.1 9.2 11.9 · 8.3 6.0 ·
Debt / Equity 9-point trend, -21.4% 0.2 -7.6 0.5 0.2 0.2 0.1 0.1 · 0.2 0.3 ·
LT Debt / Equity 9-point trend, -19.0% 0.2 -7.6 0.5 0.2 0.2 0.1 0.1 · 0.2 0.3 ·
Interest Coverage 7-point trend, +79.5% · · -6.8 -12.2 41.6 -32.8 -31.8 · -32.0 -33.1 ·
效率 3
QURE 的年度效率数据
指标 趋势 20252024202320222021202020192018201720162015
Asset Turnover 9-point trend, -79.0% 0.0 0.0 0.0 0.1 0.9 0.1 0.0 · 0.1 0.1 ·
Inventory Turnover 2-point trend, -98.0% · · 0.0 0.3 · · · · · · ·
Receivables Turnover 2-point trend, -46.6% · · · · · 7.3 · · · 13.6 ·
每股 5
QURE 的年度每股数据
指标 趋势 20252024202320222021202020192018201720162015
Book Value / Share 9-point trend, +26.7% $3.19 $-0.14 $4.34 $10.13 $12.87 $5.45 $7.39 · $2.85 $2.52 ·
Revenue / Share 5-point trend, -97.5% $0.28 $0.56 $0.33 $2.28 $11.19 · · · · · ·
Cash Flow / Share 5-point trend, -150.3% $-3.09 $-3.76 $-3.06 $-3.10 $6.15 · · · · · ·
Cash / Share 9-point trend, -75.5% $1.29 $3.24 $5.05 $4.85 $12.01 $5.47 $8.64 · $5.09 $5.25 ·
EPS (TTM) 7-point trend, -11.3% $-3.46 $-4.92 $-6.47 $-2.71 $7.04 $-2.81 $-3.11 · · · ·
增长率 3
QURE 的年度增长率数据
指标 趋势 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, -103.1% -40.6% 71.2% -85.1% -79.7% 1296.8% · · · · · ·
Revenue CAGR 3Y 3-point trend, -87.1% -46.7% -62.7% -25.0% · · · · · · · ·
Revenue CAGR 5Y -15.6% · · · · · · · · · ·
估值 (TTM) 14
QURE 的年度估值 (TTM)数据
指标 趋势 20252024202320222021202020192018201720162015
Revenue TTM 10-point trend, -35.9% $16M $27M $16M $106M $524M $38M $7M $11M $13M $25M ·
Net Income TTM 10-point trend, -171.2% $-199M $-240M $-308M $-127M $330M $-125M $-124M $-83M $-79M $-73M ·
Market Cap 9-point trend, +954.7% $1.49B $865M $324M $1.06B $960M $1.62B $3.13B · $614M $141M ·
Enterprise Value 9-point trend, +4907.2% $1.46B $758M $184M $940M $505M $1.41B $2.79B · $475M $29M ·
P/E 7-point trend, +70.0% -6.9 -3.6 -1.0 -8.4 2.9 -12.9 -23.0 · · · ·
P/S 9-point trend, +1544.3% 92.7 31.9 20.4 10.0 1.8 43.1 430.2 · 46.8 5.6 ·
P/B 9-point trend, +237.4% 7.5 -128.1 1.6 2.2 1.6 6.6 9.7 · 6.9 2.2 ·
P / Tangible Book 5-point trend, +119.6% 14.8 · 2.7 2.7 1.9 6.7 · · · · ·
P / Cash Flow 9-point trend, -327.8% -8.4 -4.7 -2.2 -7.3 3.3 -12.0 -31.7 · -9.6 -2.0 ·
P / FCF 9-point trend, -417.1% -8.4 -4.6 -2.1 -6.5 3.5 -11.4 -30.0 · -8.9 -1.6 ·
EV / EBITDA 9-point trend, -1843.6% -7.9 -4.1 -0.7 -6.6 1.6 -11.2 -23.0 · -6.7 -0.4 ·
EV / FCF 9-point trend, -2355.2% -8.2 -4.1 -1.2 -5.8 1.9 -9.9 -26.7 · -6.9 -0.3 ·
EV / Revenue 9-point trend, +7706.6% 90.8 27.9 11.6 8.8 1.0 37.5 383.3 · 36.3 1.2 ·
Earnings Yield 7-point trend, -233.2% -14.5% -27.9% -95.6% -11.9% 33.9% -7.8% -4.3% · · · ·

财务报表 损益表、资产负债表、现金流量表 — 年度,近5年

损益表
2025-12-312024-12-312023-12-312022-12-312021-12-31
收入 $16M$27M$16M$106M$524M
营业利润率 % -1151.4%-679.6%-1785.5%-134.4%59.3%
净收入 $-199M$-240M$-308M$-127M$330M
稀释后每股收益 (EPS) $-3.46$-4.92$-6.47$-2.71$7.04
资产负债表
2025-12-312024-12-312023-12-312022-12-312021-12-31
负债/股东权益比率 0.2-7.60.50.20.2
流动比率 10.49.78.86.317.1
速动比率 1.34.03.33.015.1
现金流
2025-12-312024-12-312023-12-312022-12-312021-12-31
自由现金流 $-178M$-186M$-153M$-163M$271M

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机构持有人 (13F) 315 家申报者 · $3.1B 总计 · 截至 2026年6月30日

在其季度SEC表格13F中报告持有此股票的机构。仅限多头头寸;单个申报人可能因单独的期权腿而出现两次。 大的抵消性看跌/看涨腿通常反映做市或对冲库存,而非方向性判断。

机构活动 — Q2 2026 与上一季度对比
新仓位 已退出持仓 增加 减少 净股数变动
104 (+42 与上一季度对比) 45 (-3 与上一季度对比) 87 (-1 与上一季度对比) 84 (+17 与上一季度对比) -2.2M

与Q1 2026对比。 SEC 13F表格的提交截止日期是季度末后45天,外加少量延迟提交的缓冲期——在此窗口期内的季度将被跳过,优先显示最近一个已完整报告的季度对。

机构 价值 股份 % 已追踪的13F 类型
Avoro Capital Advisors LLC $309881409 6727777 10.06% 股份
RTW INVESTMENTS, LP $181548806 3941572 5.89% 股份
STATE STREET CORP $133750180 2903825 4.34% 股份
Aberdeen Group plc $131184269 2848117 4.26% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $118728862 2577700 3.85% 买入期权
ORBIMED ADVISORS LLC $83252805 1807486 2.70% 股份
Caption Management, LLC $74967256 1627600 2.43% 买入期权
JENNISON ASSOCIATES LLC $69680259 1512815 2.26% 股份
Boxer Capital Management, LLC $69241998 1503300 2.25% 股份
GOLDMAN SACHS GROUP INC $67574626 1467100 2.19% 股份
TWO SIGMA INVESTMENTS, LP $67340825 1462024 2.19% 股份
Two Seas Capital LP $66391345 1441410 2.16% 股份
JANE STREET GROUP, LLC $58196257 1263488 1.89% 股份
MAK CAPITAL ONE LLC $56748269 1232051 1.84% 股份
MPM BIOIMPACT LLC $56462881 1225855 1.83% 股份
FMR LLC $54494830 1183127 1.77% 股份
CITADEL ADVISORS LLC $46069212 1000200 1.50% 买入期权
Vestal Point Capital, LP $43066100 935000 1.40% 股份
MAVERICK CAPITAL LTD $42623141 925383 1.38% 股份
Integral Health Asset Management, LLC $41454000 900000 1.35% 股份
Longaeva Partners L.P. $37059600 804594 1.20% 股份
Nantahala Capital Management, LLC $36848000 800000 1.20% 买入期权
VANGUARD CAPITAL MANAGEMENT LLC $35916621 779779 1.17% 股份
Fiera Capital Corp $35628515 773524 1.16% 股份
GEODE CAPITAL MANAGEMENT, LLC $32619201 707810 1.06% 股份
CITIGROUP INC $30629900 665000 0.99% 买入期权
First Turn Management, LLC $28047086 608925 0.91% 股份
Point72 Asset Management, L.P. $27922125 606212 0.91% 股份
CITADEL ADVISORS LLC $27484002 596700 0.89% 卖出期权
Balyasny Asset Management L.P. $27017967 586582 0.88% 股份
Kinetic Partners Management, LP $26760860 581000 0.87% 股份
TWO SIGMA ADVISERS, LP $26571872 1110400 0.86% 股份
683 Capital Management, LLC $26484501 575000 0.86% 股份
TUDOR INVESTMENT CORP ET AL $25254698 548300 0.82% 买入期权
JANE STREET GROUP, LLC $25231668 547800 0.82% 买入期权
GILDER GAGNON HOWE & CO LLC $24456893 530979 0.79% 股份
Invesco Ltd. $24439021 530591 0.79% 股份
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. $24028443 521677 0.78% 股份
Assenagon Asset Management S.A. $23653192 513530 0.77% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $22887076 496897 0.74% 股份
Nantahala Capital Management, LLC $20987700 455660 0.68% 股份
Voss Capital, LP $20743628 450361 0.67% 股份
CITADEL ADVISORS LLC $20275658 440201 0.66% 股份
SUSQUEHANNA INTERNATIONAL GROUP, LLP $19349806 420100 0.63% 卖出期权
Rubric Capital Management LP $18819241 408581 0.61% 股份
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $18577748 403338 0.60% 股份
READYSTATE ASSET MANAGEMENT LP $18469553 400989 0.60% 股份
VANGUARD FIDUCIARY TRUST CO $17024098 369607 0.55% 股份
MILLENNIUM MANAGEMENT LLC $15804384 343126 0.51% 股份
Creek Drive Management Group LLC $15522220 337000 0.50% 股份
TUDOR INVESTMENT CORP ET AL $15148627 328889 0.49% 股份
Privium Fund Management B.V. $15122511 328322 0.49% 股份
ADAR1 Capital Management, LLC $14954392 324672 0.49% 股份
683 Capital Management, LLC $14564172 316200 0.47% 买入期权
BRAIDWELL LP $13894091 301652 0.45% 股份
DIADEMA PARTNERS LP $13771940 299000 0.45% 卖出期权
Squarepoint Ops LLC $12910618 280300 0.42% 股份
NEW YORK STATE COMMON RETIREMENT FUND $11249602 244238 0.37% 股份
DIADEMA PARTNERS LP $10842524 235400 0.35% 买入期权
FourWorld Capital Management LLC $10133200 220000 0.33% 买入期权
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $10018000 217500 0.33% 股份
Parkman Healthcare Partners LLC $9588310 208170 0.31% 股份
D. E. Shaw & Co., Inc. $9563392 207629 0.31% 股份
TUDOR INVESTMENT CORP ET AL $9396240 204000 0.31% 卖出期权
BANK OF AMERICA CORP /DE/ $9386844 203796 0.30% 股份
Caption Management, LLC $9262666 201100 0.30% 卖出期权
Affinity Asset Advisors, LLC $9212000 200000 0.30% 买入期权
MILLENNIUM MANAGEMENT LLC $9202788 199800 0.30% 买入期权
Diametric Capital, LP $9084966 197242 0.29% 股份
BARCLAYS PLC $8686916 188600 0.28% 买入期权
PICTON MAHONEY ASSET MANAGEMENT $8346765 181215 0.27% 股份
Affinity Asset Advisors, LLC $8060500 175000 0.26% 股份
Trexquant Investment LP $7883123 171149 0.26% 股份
PERCEPTIVE ADVISORS LLC $7738080 168000 0.25% 股份
VANGUARD GROUP INC $7660137 320106 0.25% 股份
Nantahala Capital Management, LLC $7438690 161500 0.24% 卖出期权
FLAX POND CAPITAL, LLC $7218800 156726 0.23% 股份
AMERIPRISE FINANCIAL INC $7002133 152022 0.23% 股份
Casdin Capital, LLC $6909000 150000 0.22% 股份
LMR Partners LLP $6909000 150000 0.22% 买入期权
MARSHALL WACE, LLP $6615321 143624 0.21% 股份
WOLVERINE TRADING, LLC $6599340 111100 0.21% 买入期权
VANGUARD PORTFOLIO MANAGEMENT LLC $6498744 141093 0.21% 股份
UBS Group AG $6110412 132662 0.20% 股份
CITIGROUP INC $5893101 127944 0.19% 股份
SIG BROKERAGE, LP $5872650 127500 0.19% 买入期权
ENVESTNET ASSET MANAGEMENT INC $5830106 126576 0.19% 股份
Susquehanna Portfolio Strategies, LLC $5613286 121869 0.18% 股份
Hudson Bay Capital Management LP $5527200 120000 0.18% 股份
WOLVERINE TRADING, LLC $5482620 92300 0.18% 卖出期权
NAN FUNG TRINITY (HK) LTD $5319654 115494 0.17% 股份
SIMPLEX TRADING, LLC $5076687 110219 0.16% 股份
SILVERARC CAPITAL MANAGEMENT, LLC $4836300 105000 0.16% 股份
Ghisallo Capital Management LLC $4606000 100000 0.15% 股份
Pekin Hardy Strauss, Inc. $4341155 94250 0.14% 股份
Swiss National Bank $4334246 94100 0.14% 股份
JANE STREET GROUP, LLC $4209884 91400 0.14% 卖出期权
STEMPOINT CAPITAL LP $4058577 88115 0.13% 股份
FourWorld Capital Management LLC $4007220 87000 0.13% 股份
Marex Group Ltd $3753890 81500 0.12% 股份

公司内部人士 28 位内幕人士 · 17 位高管 · 12 位董事

内部人士 角色 上次活动 持股数量 买入 12个月 卖出 12个月 净额 12个月
Matthew C Kapusta CEO, Managing Director 2026年7月2日 M 519227 0 21 $-22247399
Christian Klemt Chief Financial Officer 2026年3月4日 A 226581 0 5 $-1326871
Ricardo Dolmetsch President, R&D 2023年9月18日 S 163404 0 0 $0
Pierre Caloz Chief Operating Officer 2024年6月17日 S 115707 0 0 $0
Scott T. Mcmillan Chief Operating Officer 2019年1月28日 S 20432 0 0 $0
Walid Abi-Saab Chief Medical Officer 2026年6月30日 M 148235 0 7 $-2611134
Jeannette Potts Chief Legal Officer 2026年6月15日 S 133246 0 3 $-261172
Kylie O'Keefe Chief Customer & Strat Officer 2026年6月11日 S 108864 0 1 $-431228
Alexander Edward Kuta III Executive VP, Operations 2023年3月7日 S 90381 0 0 $0
Sander Van Deventer EVP, Research & Product Dev. 2020年2月27日 A 61599 0 0 $0
Steven Zelenkofske Chief Medical Officer 2018年6月6日 S 159458 0 0 $0
Jonathan Garen Chief Business Officer 2018年1月26日 A 93638 0 0 $0
Paul E Firuta Chief Commercial Officer 2018年1月26日 A 93817 0 0 $0
Maria E Cantor SVP, Investor Rel. & Comm. 2018年1月26日 A 92439 0 0 $0
Harald Petry Chief Scientific Officer 2017年6月29日 M 0 0 0 $0
Christian Meyer Chief Medical Officer 2017年1月27日 A 0 0 $0
Maiken Keson-Brookes General Counsel 2017年1月27日 A 0 0 $0
Jack Kaye 董事 2026年6月30日 M 25996 0 9 $-2693581
Madhavan Balachandran 董事 2026年6月17日 M 43254 0 5 $-858916
Rachelle Suzanne Jacques 董事 2026年6月10日 A 33903 0 1 $-53931
Jeremy P. Springhorn 董事 2026年6月10日 A 43251 0 1 $-53931
Robert Gut 董事 2026年6月10日 A 32259 0 9 $-1757850
David D. Meek 董事 2026年6月10日 A 39747 0 1 $-53931
Leonard E Post 董事 2026年6月10日 A 35494 0 1 $-53931
Paula Soteropoulos 董事 2024年6月13日 S 20203 0 0 $0
Philip Astley-Sparke 董事 2021年3月2日 S 9946 0 0 $0
David Schaffer 董事 2020年2月27日 A 46978 0 0 $0
William Lewis 董事 2017年1月27日 A 0 0 $0

来自SEC表格3/4/5申报的内部人士;净额=仅公开市场买卖

激进投资者及 5%+ 股东 1 持仓

提交了 SEC Schedule 13D 的投资者 — 持有超过 5% 的受益所有权,意图影响发行人(激进股东持股、董事会活动、并购)。每一行显示该申报人持仓的最新已知状态。

申报人 已申报 持股 状态 目的 申报
Coller Investment Management Limited, Coller International General Partner V, L.P, Coller International Partners V-A, L.P ×4 申报 2019年4月3日 初始申报 SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF持仓 由 14 只交易所交易基金持有

权重仅反映直接股权持仓(N-PORT);杠杆基金或基于衍生品的基金可能持有未显示的额外掉期敞口。

基金 权重 单位 截至 来源
GNOM · Global X Funds 1.59% 31188 NS 2026年5月31日 N-PORT
LABU · Direxion Shares ETF Trust 0.37% 97163 NS 2026年4月30日 N-PORT
ESIM · Strategy Shares 0.11% 867 NS 2026年4月30日 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 52 NS 2026年5月31日 N-PORT
VXF · VANGUARD INDEX FUNDS 2026年7月15日 每日
ITOT · iShares Trust 2026年8月4日 每日
IBB · iShares Trust 2026年8月18日 每日
PTH · Invesco Exchange-Traded Fund Trust 2026年7月13日 每日
VHT · VANGUARD WORLD FUND 2026年7月20日 每日
ISCB · iShares Trust 2026年8月4日 每日
ISCV · iShares Trust 2026年8月4日 每日
WSML · iShares Trust 2026年8月4日 每日
DWAS · Invesco Exchange-Traded Fund Trus... 2026年7月20日 每日
IBBQ · Invesco Exchange-Traded Fund Trus... 2026年8月17日 每日