| JANUS HENDERSON GROUP PLC |
$76892206 |
11063862 |
11.06% |
股份
|
| BlackRock, Inc. |
$51393319 |
7426780 |
7.39% |
股份
|
| Squadron Capital Management LLC |
$50862000 |
7350000 |
7.31% |
股份
|
| Venrock Adviser, LLC |
$47362591 |
6844305 |
6.81% |
股份
|
| Spruce Street Capital LP |
$44227990 |
6391328 |
6.36% |
股份
|
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
$32961053 |
4763158 |
4.74% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$30864653 |
4460210 |
4.44% |
股份
|
| Jones Hill Capital LP |
$25293119 |
3655075 |
3.64% |
股份
|
| ORBIMED ADVISORS LLC |
$25127869 |
3631195 |
3.61% |
股份
|
| STATE STREET CORP |
$17421446 |
2517550 |
2.51% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$17253429 |
2492573 |
2.48% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$16343843 |
2361827 |
2.35% |
股份
|
| MARSHALL WACE, LLP |
$15548126 |
2246839 |
2.24% |
股份
|
| Ikarian Capital, LLC |
$14866644 |
2148359 |
2.14% |
股份
|
| Driehaus Capital Management LLC |
$14753807 |
2132053 |
2.12% |
股份
|
| AMERIPRISE FINANCIAL INC |
$13410767 |
1937972 |
1.93% |
股份
|
| EVENTIDE ASSET MANAGEMENT, LLC |
$12860239 |
1858416 |
1.85% |
股份
|
| Balyasny Asset Management L.P. |
$10523161 |
1520688 |
1.51% |
股份
|
| STEMPOINT CAPITAL LP |
$10103844 |
1460093 |
1.45% |
股份
|
| Commodore Capital LP |
$9861000 |
1425000 |
1.42% |
股份
|
| Polar Capital Holdings Plc |
$9275762 |
1340428 |
1.33% |
股份
|
| CITADEL ADVISORS LLC |
$7346722 |
1061665 |
1.06% |
股份
|
| Sio Capital Management, LLC |
$6944649 |
1003562 |
1.00% |
股份
|
| Opaleye Management Inc. |
$6470200 |
935000 |
0.93% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$6215530 |
898198 |
0.89% |
股份
|
| Boxer Capital Management, LLC |
$5827374 |
842106 |
0.84% |
股份
|
| Soleus Capital Management, L.P. |
$5827374 |
842106 |
0.84% |
股份
|
| GREAT POINT PARTNERS LLC |
$5827374 |
842106 |
0.84% |
股份
|
| VANGUARD GROUP INC |
$5811973 |
1203307 |
0.84% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$5619449 |
812059 |
0.81% |
股份
|
| NORTHERN TRUST CORP |
$5440898 |
786257 |
0.78% |
股份
|
| GOLDMAN SACHS GROUP INC |
$5311958 |
767624 |
0.76% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$5080602 |
734191 |
0.73% |
股份
|
| Qube Research & Technologies Ltd |
$4785491 |
691545 |
0.69% |
股份
|
| Walleye Capital LLC |
$4264367 |
616238 |
0.61% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$3908132 |
564759 |
0.56% |
股份
|
| Integral Health Asset Management, LLC |
$3460000 |
500000 |
0.50% |
股份
|
| ADAR1 Capital Management, LLC |
$3127273 |
451918 |
0.45% |
股份
|
| Knott David M Jr |
$3120920 |
451000 |
0.45% |
股份
|
| HighVista Strategies LLC |
$3084929 |
445799 |
0.44% |
股份
|
| AdvisorShares Investments LLC |
$3037195 |
438901 |
0.44% |
股份
|
| Birchview Capital, LP |
$2824052 |
408100 |
0.41% |
股份
|
| DIADEMA PARTNERS LP |
$2500660 |
361367 |
0.36% |
股份
|
| PARSONS CAPITAL MANAGEMENT INC/RI |
$2450158 |
354069 |
0.35% |
股份
|
| Seven Fleet Capital Management LP |
$2409994 |
348265 |
0.35% |
股份
|
| Harvest Investment Services, LLC |
$2358959 |
340890 |
0.34% |
股份
|
| Woodline Partners LP |
$2272673 |
328421 |
0.33% |
股份
|
| DEUTSCHE BANK AG\ |
$2206802 |
318902 |
0.32% |
股份
|
| SEVEN GRAND MANAGERS, LLC |
$2185253 |
315788 |
0.31% |
股份
|
| Bank of New York Mellon Corp |
$2045711 |
295623 |
0.29% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$1956402 |
282717 |
0.28% |
股份
|
| Nuveen, LLC |
$1557464 |
225067 |
0.22% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$1487212 |
214915 |
0.21% |
股份
|
| UBS Group AG |
$1093589 |
158033 |
0.16% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$1077533 |
155713 |
0.15% |
股份
|
| RHUMBLINE ADVISERS |
$817298 |
118108 |
0.12% |
股份
|
| TWO SIGMA ADVISERS, LP |
$783426 |
162200 |
0.11% |
股份
|
| D. E. Shaw & Co., Inc. |
$757560 |
109474 |
0.11% |
股份
|
| CITADEL ADVISORS LLC |
$754280 |
109000 |
0.11% |
买入期权
|
| ALPS ADVISORS INC |
$736676 |
106456 |
0.11% |
股份
|
| MGO ONE SEVEN LLC |
$692000 |
100000 |
0.10% |
股份
|
| Eversept Partners, LP |
$644889 |
93192 |
0.09% |
股份
|
| Invesco Ltd. |
$620523 |
89671 |
0.09% |
股份
|
| Informed Momentum Co LLC |
$612053 |
88447 |
0.09% |
股份
|
| Verdad Advisers, LP |
$601998 |
86994 |
0.09% |
股份
|
| Persistent Asset Partners Ltd |
$598186 |
86443 |
0.09% |
股份
|
| WELLS FARGO & COMPANY/MN |
$596940 |
86263 |
0.09% |
股份
|
| MORGAN STANLEY |
$573135 |
82823 |
0.08% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$526612 |
76100 |
0.08% |
买入期权
|
| CITIGROUP INC |
$496530 |
71753 |
0.07% |
股份
|
| MANGROVE PARTNERS IM, LLC |
$496199 |
71705 |
0.07% |
股份
|
| SEI INVESTMENTS CO |
$480075 |
69375 |
0.07% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$466048 |
67348 |
0.07% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$441496 |
63800 |
0.06% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$399976 |
57800 |
0.06% |
股份
|
| LMR Partners LLP |
$384752 |
55600 |
0.06% |
股份
|
| MetLife Investment Management, LLC |
$384489 |
55562 |
0.06% |
股份
|
| BARCLAYS PLC |
$354538 |
51234 |
0.05% |
股份
|
| Virtus Investment Advisers, LLC |
$340478 |
49202 |
0.05% |
股份
|
| LPL Financial LLC |
$336111 |
48571 |
0.05% |
股份
|
| apricus wealth, LLC |
$328437 |
47462 |
0.05% |
股份
|
| Vanguard Global Advisers, LLC |
$305608 |
44163 |
0.04% |
股份
|
| Trexquant Investment LP |
$302722 |
43746 |
0.04% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$300051 |
43360 |
0.04% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$275616 |
39600 |
0.04% |
股份
|
| JPMORGAN CHASE & CO |
$273637 |
39203 |
0.04% |
股份
|
| AlTi Global, Inc. |
$221267 |
31975 |
0.03% |
股份
|
| Pale Fire Capital SE |
$219018 |
31650 |
0.03% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$208347 |
30108 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$192999 |
27890 |
0.03% |
股份
|
| PROFUND ADVISORS LLC |
$189096 |
27326 |
0.03% |
股份
|
| Belvedere Trading LLC |
$187532 |
27100 |
0.03% |
买入期权
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$179920 |
26000 |
0.03% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$173187 |
25027 |
0.02% |
股份
|
| Robertson Stephens Wealth Management, LLC |
$173000 |
25000 |
0.02% |
股份
|
| State of Wyoming |
$142455 |
20586 |
0.02% |
股份
|
| Rafferty Asset Management, LLC |
$137729 |
19903 |
0.02% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$136462 |
19720 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$124145 |
17940 |
0.02% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$110858 |
16020 |
0.02% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$99849 |
14429 |
0.01% |
股份
|
| Pandora Wealth, Inc. |
$96600 |
20000 |
0.01% |
股份
|
| Lido Advisors, LLC |
$96223 |
13905 |
0.01% |
股份
|
| Keebeck Wealth Management |
$89960 |
13000 |
0.01% |
股份
|
| ProShare Advisors LLC |
$85676 |
12381 |
0.01% |
股份
|
| AXQ CAPITAL, LP |
$83684 |
12093 |
0.01% |
股份
|
| Scientech Research LLC |
$81836 |
11826 |
0.01% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$73608 |
10637 |
0.01% |
股份
|
| World Investment Advisors |
$72691 |
10444 |
0.01% |
股份
|
| Bedel Financial Consulting, Inc. |
$69200 |
10000 |
0.01% |
股份
|
| Legal & General Group Plc |
$63533 |
9181 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$59387 |
8582 |
0.01% |
股份
|
| Russell Investments Group, Ltd. |
$52329 |
7562 |
0.01% |
股份
|
| EverSource Wealth Advisors, LLC |
$47167 |
6816 |
0.01% |
股份
|
| Tower Research Capital LLC (TRC) |
$42807 |
6186 |
0.01% |
股份
|
| Caitong International Asset Management Co., Ltd |
$22490 |
3250 |
0.00% |
股份
|
| ROYAL BANK OF CANADA |
$21000 |
3066 |
0.00% |
股份
|
| ANTIPODES PARTNERS Ltd |
$16705 |
2414 |
0.00% |
股份
|
| Allworth Financial LP |
$13840 |
2000 |
0.00% |
股份
|
| American Capital Advisory, LLC |
$13522 |
1954 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$9010 |
1302 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$3759 |
543394 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$3633 |
525 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$2297 |
332 |
0.00% |
股份
|
| FMR LLC |
$1107 |
160 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$979 |
141443 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$538 |
77668 |
0.00% |
股份
|
| GAMMA Investing LLC |
$284 |
41 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$35 |
5 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$34 |
5 |
0.00% |
股份
|
| Front Row Advisors LLC |
$9 |
2 |
0.00% |
股份
|