CUE Cue Biopharma, Inc. - Common Stock
$26.95
Price · Aug 18, 2026
Fundamentals as of Aug 14, 2026
52W Range
$0–$46
59% of range
Analyst Rating
BUY
5 analysts
Price Target
$115
+327% upside
P/E (TTM)
-3.2
ROE
-119.3%
Net Profit Margin
-96.9%
CUE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$26.95
Market Cap
$87M
P/E (TTM)
-3.2
EPS (TTM)
$-0.28
Revenue (TTM)
$27M
Div Yield
—
ROE
-119.3%
Debt/Equity
—
52W Range
$0 – $46
CUE Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$27M
2018-12-31
→
2025-12-31
EPS
$-0.28
2021-12-31
→
2025-12-31
Free Cash Flow
$-22M
2020-12-31
→
2025-12-31
Margins
-96.9%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
CUE
Peer Median
P/E (TTM)
-3.2
1.2
P/S (TTM)
3.2
6.3
P/B
3.3
1.6
Price / FCF
-4.0
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
CUE
Peer Median
Operating Margin
-96.7%
—
Net Profit Margin
-96.9%
-312.6%
ROA
-71.5%
-56.8%
ROE
-119.3%
-83.3%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
CUE
Peer Median
Current Ratio
2.7
8.5
Quick Ratio
2.4
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
CUE
Peer Median
Revenue YoY
195.8%
—
Revenue CAGR 3Y
180.5%
—
Revenue CAGR 5Y
54.2%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
CUE
Peer Median
CUE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
5 analysts
- Strong Buy 1 20.0%
- Buy 3 60.0%
- Hold 1 20.0%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
1 analysts · 2026-08-16
Low
$115.00
High
$115.00
Median target
$115.00
+326.7%
Mean target
$115.00
+326.7%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.66%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| Sept. 30, 2025 | $-2.10 | $-2.83 | 0.73% |
| June 30, 2025 | $-2.70 | $-4.24 | 1.5% |
| March 31, 2025 | $-5.10 | $-4.65 | -0.45% |
| Dec. 31, 2024 | $-3.90 | $-4.73 | 0.83% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| CUE | $29M | -1.1 | 195.8% | -96.9% | -119.3% | — |
| KROS | $398M | 8.9 | — | 35.7% | 17.2% | — |
| DTIL | $100M | -1.2 | -50.1% | -133.4% | -72.4% | — |
| CRBP | $143M | -1.4 | — | — | -60.8% | — |
| KRRO | $75M | -0.6 | 181.5% | -1834.5% | -140.8% | — |
| ABOS | $128M | -1.1 | — | — | -129.4% | — |
| VYGR | $232M | -1.9 | -49.5% | -296.5% | -54.4% | — |
| CHRS | $172M | 1.0 | 59.8% | 398.4% | 185.8% | — |
| NKTX | $131M | -1.3 | — | — | -31.1% | — |
| OKUR | — | -0.7 | — | -1733.7% | -88.6% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 15
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | $27M | $9M | $5M | $1M | $15M | $3M | $3M | $1M | |
| R&D Expense | $38M | $36M | $41M | $39M | $41M | $34M | $27M | $29M | |
| SG&A Expense | $16M | $15M | $17M | $16M | $17M | $15M | $13M | $11M | |
| Operating Expenses | $54M | $51M | $58M | $54M | $59M | $48M | $40M | $40M | |
| Operating Income | $-27M | $-42M | $-52M | $-53M | $-44M | $-45M | $-37M | $-39M | |
| Interest Expense | $100.0K | $100.0K | $100.0K | $109.0K | · | · | · | · | |
| Other Non-op | $450.0K | $826.0K | $1M | $215.0K | $45.9K | $463.9K | $482.8K | $165.3K | |
| Pretax Income | · | · | · | $-53M | $-44M | $-45M | $-36M | $-38M | |
| Income Tax | $500.0K | $0 | · | $0 | $495.0K | $206.2K | $412.5K | $825.0K | |
| Net Income | $-27M | $-41M | $-51M | $-53M | $-44M | $-45M | $-37M | $-39M | |
| EPS (Basic) | $-0.28 | $-0.72 | $-1.11 | $-1.49 | $-1.41 | · | · | · | |
| EPS (Diluted) | $-0.28 | $-0.72 | $-1.11 | $-1.49 | $-1.41 | · | · | · | |
| Shares (Basic) | 94,731,768 | 56,328,348 | 45,754,794 | 35,649,134 | 31,285,418 | · | · | · | |
| Shares (Diluted) | 94,731,768 | 56,328,348 | 45,754,794 | 35,649,134 | 31,285,418 | · | · | · | |
| EBITDA | $-27M | $-42M | $-52M | $-53M | $-44M | $-45M | · | · |
Balance Sheet 23
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $27M | $22M | $49M | $52M | $64M | $75M | $44M | $21M | |
| Receivables | $6M | $945.0K | $2M | $57.0K | $3M | $1M | $754.9K | · | |
| Prepaid Expense | $1M | $805.0K | $955.0K | $841.0K | $954.8K | $1M | $860.1K | $1M | |
| Current Assets | $37M | $25M | $51M | $77M | $68M | $88M | $61M | $41M | |
| PP&E (Net) | $241.0K | $471.0K | $795.0K | $1M | $2M | $2M | $2M | $3M | |
| PP&E (Gross) | $4M | $4M | $4M | $6M | $6M | $5M | $4M | $4M | |
| Accum. Depreciation | $4M | $4M | $4M | $4M | $3M | $3M | $2M | $1M | |
| Other Non-current Assets | $94.0K | $105.0K | $117.0K | $128.0K | $140.0K | $401.7K | $673.6K | $808.7K | |
| Total Assets | $42M | $32M | $62M | $91M | $83M | $100M | $72M | $45M | |
| Accounts Payable | $4M | $3M | $4M | $3M | $3M | $2M | $882.7K | $2M | |
| Accrued Liabilities | $2M | $3M | $4M | $4M | $5M | $3M | $2M | $2M | |
| Short-term Debt | · | $37.0K | $37.0K | $74.0K | · | · | · | · | |
| Current Liabilities | $13M | $14M | $17M | $12M | $13M | $16M | $12M | $6M | |
| Capital Leases | $2M | $1M | $3M | $6M | $5M | $2M | $1M | · | |
| Total Liabilities | $16M | $15M | $24M | $26M | $18M | $21M | $17M | $11M | |
| Long-term Debt | · | · | $4M | $8M | · | · | · | · | |
| Total Debt | · | $37.0K | $8M | $10M | · | · | · | · | |
| Common Stock | $3.0K | $62.0K | $47.0K | $43.0K | $32.2K | $30.4K | $26.6K | $20.7K | |
| Retained Earnings | $-368M | $-342M | $-301M | $-250M | $-197M | $-153M | $-109M | $-72M | |
| AOCI | · | $0 | $0 | $-96.0K | $0 | $7.1K | $-10.3K | $-11.0K | |
| Stockholders' Equity | $26M | $17M | $37M | $66M | $65M | $79M | $55M | $34M | |
| Liabilities + Equity | $42M | $32M | $62M | $91M | $83M | $100M | $72M | $45M | |
| Shares Outstanding | 3,220,707 | 61,819,101 | 47,215,116 | 47,215,116 | 32,202,496 | 30,351,366 | 26,562,178 | 20,697,453 |
Cash Flow 13
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| D&A | $958.0K | $397.0K | $556.0K | $922.0K | $1M | $1M | $810.8K | $760.0K | |
| Stock-based Comp | $5M | $7M | $8M | $9M | $12M | $10M | $7M | $7M | |
| Amort. of Intangibles | · | · | · | · | · | $11.7K | $11.7K | · | |
| Operating Cash Flow | $-22M | $-36M | $-40M | $-42M | $-39M | $-32M | $-31M | $-26M | |
| CapEx | $177.0K | $66.0K | $0 | $171.0K | $913.0K | $595.3K | $46.4K | $2M | |
| Investing Cash Flow | $75.0K | $32.0K | $25M | $-25M | $9M | $4M | $3M | $-20M | |
| Stock Issued | $28M | $11M | $0 | $23M | $0 | $57M | $49M | · | |
| Stock Repurchased | · | · | $0 | $200.0K | $750.1K | $271.1K | $91.0K | · | |
| Net Stock Activity | $28M | $11M | $0 | $23M | $17M | $56M | · | · | |
| Financing Cash Flow | $26M | $10M | $12M | $54M | $19M | $59M | $51M | $4M | |
| Net Change in Cash | $5M | $-26M | $-3M | $-13M | $-10M | $31M | $23M | $-43M | |
| Taxes Paid | $500.0K | $0 | · | · | · | · | · | · | |
| Free Cash Flow | $-22M | $-36M | $-40M | $-42M | $-40M | $-33M | · | · |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -96.7% | -446.9% | -949.9% | -4274.3% | -292.6% | -1428.0% | · | · | |
| Net Margin | -96.9% | -438.0% | -924.1% | -4257.1% | -295.6% | -1419.8% | · | · | |
| Pretax Margin | · | · | · | -4257.1% | -292.2% | -1413.3% | · | · | |
| EBITDA Margin | -96.7% | -446.9% | -949.9% | -4274.3% | -292.6% | -1428.0% | · | · | |
| ROA | -71.5% | -86.8% | -66.4% | -60.7% | -48.3% | -52.3% | · | · | |
| ROE | -119.3% | -189.8% | -127.2% | -91.0% | -68.5% | -53.8% | · | · | |
| ROIC | · | · | · | -70.2% | -67.5% | -57.3% | · | · |
Liquidity & Solvency 5
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.7 | 1.8 | 3.0 | 6.7 | 5.4 | 5.4 | · | · | |
| Quick Ratio | 2.4 | 1.7 | 2.9 | 4.5 | 5.3 | 4.7 | · | · | |
| Debt / Equity | · | 0.0 | 0.2 | 0.2 | · | · | · | · | |
| LT Debt / Equity | · | 0.0 | 0.1 | 0.1 | · | · | · | · | |
| Interest Coverage | -265.5 | -415.0 | -401.1 | · | · | · | · | · |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.7 | 0.2 | 0.1 | 0.0 | 0.2 | 0.0 | · | · | |
| Receivables Turnover | 8.5 | 7.0 | 6.3 | 0.8 | 6.6 | 2.9 | · | · |
Growth Rates 3
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 195.8% | 69.2% | 341.0% | -91.7% | 373.7% | · | · | · | |
| Revenue CAGR 3Y | 180.5% | -14.7% | 20.3% | · | · | · | · | · | |
| Revenue CAGR 5Y | 54.2% | · | · | · | · | · | · | · |
Valuation (TTM) 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $27M | $9M | $5M | $1M | $15M | $3M | $3M | $1M | |
| Net Income TTM | $-27M | $-41M | $-51M | $-53M | $-44M | $-45M | $-37M | $-39M | |
| Market Cap | $29M | $67M | $114M | $123M | $364M | $380M | · | · | |
| Enterprise Value | · | $45M | $73M | $81M | · | · | · | · | |
| P/E | -1.1 | -1.5 | -2.4 | -1.9 | -8.0 | · | · | · | |
| P/S | 1.1 | 7.3 | 20.7 | 98.5 | 24.4 | 120.4 | · | · | |
| P/B | 1.1 | 3.9 | 3.1 | 1.9 | 5.6 | 4.8 | · | · | |
| P / Tangible Book | 1.1 | 3.9 | 3.1 | 1.9 | 5.6 | 4.8 | · | · | |
| P / Cash Flow | -1.4 | -1.9 | -2.8 | -2.9 | -9.4 | -11.7 | · | · | |
| P / FCF | -1.3 | -1.9 | -2.8 | -2.9 | -9.2 | -11.5 | · | · | |
| EV / EBITDA | · | -1.1 | -1.4 | -1.5 | · | · | · | · | |
| EV / FCF | · | -1.2 | -1.8 | -1.9 | · | · | · | · | |
| EV / Revenue | · | 4.8 | 13.4 | 65.2 | · | · | · | · | |
| Earnings Yield | -91.8% | -66.1% | -42.0% | -52.3% | -12.5% | · | · | · |
Income Statement 13
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $8M | $6M | $22M | $2M | $3M | $421.0K | $2M | $3M | $3M | $2M | $2M | $2M | $1M | $187.0K | $151.0K | $68.0K | |
| R&D Expense | $49M | $7M | $17M | $5M | $8M | $9M | $7M | $9M | $10M | $10M | $11M | $10M | $11M | $9M | $11M | $8M | |
| SG&A Expense | $47M | $4M | $3M | $5M | $4M | $4M | $4M | $3M | $4M | $4M | $5M | $4M | $4M | $4M | $4M | $4M | |
| Operating Expenses | $96M | $11M | $20M | $10M | $12M | $13M | $11M | $12M | $13M | $14M | $16M | $14M | $15M | $14M | $15M | $11M | |
| Operating Income | $-88M | $-5M | $2M | $-8M | $-9M | $-12M | $-10M | $-9M | $-10M | $-13M | $-14M | $-11M | $-14M | $-13M | $-15M | $-11M | |
| Interest Expense | · | · | · | · | $33.0K | $100.0K | · | · | · | $33.0K | $-537.0K | $254.0K | $350.0K | $33.0K | $18.0K | $33.0K | |
| Other Non-op | $-65M | $175.0K | $108.0K | $147.0K | $153.0K | $42.0K | $138.0K | $155.0K | $212.0K | $321.0K | $399.0K | $414.0K | $332.0K | $271.0K | $274.0K | $76.0K | |
| Net Income | $-153M | $-5M | $2M | $-7M | $-8M | $-12M | $-9M | $-9M | $-10M | $-12M | $-13M | $-11M | $-13M | $-13M | $-15M | $-11M | |
| EPS (Basic) | $-24.14 | $-1.08 | $0.05 | $-0.07 | $-2.67 | $-4.95 | $-0.10 | $-0.17 | $-0.20 | $-0.25 | $-0.29 | $-0.24 | $-0.29 | $-0.29 | $-0.37 | $-0.31 | |
| EPS (Diluted) | $-24.14 | $-1.08 | $0.05 | $-0.07 | $-2.67 | $-4.95 | $-0.10 | $-0.17 | $-0.20 | $-0.25 | $-0.29 | $-0.24 | $-0.29 | $-0.29 | $-0.37 | $-0.31 | |
| Shares (Basic) | 6,340,844 | 4,807,494 | -175,851,682 | 100,869,349 | 3,181,980 | 2,475,156 | -94,542,820 | 51,229,701 | 50,174,756 | 49,466,711 | -90,054,874 | 46,358,555 | 44,798,760 | 44,652,353 | -67,728,022 | 35,383,430 | |
| Shares (Diluted) | 6,340,844 | 4,807,494 | -175,851,682 | 100,869,349 | 3,181,980 | 2,475,156 | -94,542,820 | 51,229,701 | 50,174,756 | 49,466,711 | -90,054,874 | 46,358,555 | 44,798,760 | 44,652,353 | -67,728,022 | 35,383,430 | |
| EBITDA | $-88M | $-5M | · | $-8M | $-9M | $-12M | · | $-9M | $-10M | $-13M | · | $-11M | $-14M | $-13M | · | $-11M |
Balance Sheet 23
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $17M | $16M | $27M | $12M | $27M | $13M | $22M | $32M | $30M | $41M | $49M | $55M | $53M | $56M | $52M | $30M | |
| Receivables | $5M | $5M | $6M | $387.0K | $532.0K | $0 | $945.0K | $3M | $2M | $1M | $2M | $2M | $1M | $196.0K | $57.0K | $796.0K | |
| Prepaid Expense | $2M | $2M | $1M | $3M | $2M | $2M | $805.0K | $2M | $2M | $2M | $955.0K | $1M | $2M | $2M | $841.0K | $2M | |
| Current Assets | $27M | $26M | $37M | $26M | $31M | $16M | $25M | $37M | $34M | $45M | $51M | $58M | $61M | $69M | $77M | $62M | |
| PP&E (Net) | $255.0K | $288.0K | $241.0K | $307.0K | $454.0K | $523.0K | $471.0K | $570.0K | $667.0K | $754.0K | $795.0K | $1M | $1M | $1M | $1M | $2M | |
| PP&E (Gross) | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $6M | $6M | $6M | $6M | $6M | |
| Accum. Depreciation | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $5M | $4M | $4M | $4M | |
| Other Non-current Assets | $88.0K | $90.0K | $94.0K | $96.0K | $283.0K | $102.0K | $105.0K | $108.0K | $111.0K | $114.0K | $117.0K | $120.0K | $123.0K | $125.0K | $128.0K | $131.0K | |
| Total Assets | $31M | $31M | $42M | $32M | $41M | $22M | $32M | $45M | $42M | $54M | $62M | $69M | $73M | $82M | $91M | $76M | |
| Accounts Payable | $4M | $3M | $4M | $2M | $4M | $4M | $3M | $6M | $4M | $4M | $4M | $2M | $2M | $2M | $3M | $2M | |
| Accrued Liabilities | $15M | $1M | $2M | $2M | $2M | $4M | $3M | $3M | $5M | $5M | $4M | $5M | $4M | $3M | $4M | $4M | |
| Short-term Debt | · | · | · | · | · | $100.0K | · | · | · | $37.0K | · | · | · | · | · | $37.0K | |
| Current Liabilities | $21M | $7M | $13M | $16M | $19M | $15M | $14M | $17M | $16M | $18M | $17M | $17M | $16M | $14M | $12M | $10M | |
| Capital Leases | $1M | $2M | $2M | $3M | $3M | $176.0K | $1M | $1M | $2M | $3M | $3M | $4M | $5M | $5M | $6M | $6M | |
| Total Liabilities | $28M | $9M | $16M | $18M | $23M | $16M | $15M | $19M | $21M | $24M | $24M | $26M | $27M | $27M | $26M | $26M | |
| Long-term Debt | · | · | · | · | · | · | · | $1M | $2M | $3M | · | $5M | $6M | $7M | · | $9M | |
| Total Debt | · | · | · | · | · | $100.0K | · | $5M | $6M | $7M | · | $9M | $10M | $10M | · | $10M | |
| Common Stock | $5.0K | $3.0K | $97.0K | $78.0K | $76.0K | $62.0K | $62.0K | $60.0K | $48.0K | $48.0K | $47.0K | $45.0K | $44.0K | $43.0K | $43.0K | $35.0K | |
| Retained Earnings | $-527M | $-374M | $-368M | $-370M | $-363M | $-354M | $-342M | $-332M | $-324M | $-314M | $-301M | $-288M | $-277M | $-264M | $-250M | $-236M | |
| AOCI | · | · | · | $1.0K | · | · | · | · | · | · | · | $0 | $-5.0K | $-39.0K | $-96.0K | $-92.0K | |
| Stockholders' Equity | $2M | $22M | $26M | $13M | $18M | $7M | $17M | $25M | $22M | $30M | $37M | $43M | $46M | $55M | $66M | $51M | |
| Liabilities + Equity | $31M | $31M | $42M | $32M | $41M | $22M | $32M | $45M | $42M | $54M | $62M | $69M | $73M | $82M | $91M | $76M | |
| Shares Outstanding | 5,229,392 | 3,255,359 | 96,621,218 | 77,781,743 | 76,446,884 | 61,819,101 | 61,819,101 | 60,207,717 | 48,643,316 | 48,643,316 | 47,215,116 | 45,123,281 | 43,744,414 | 43,178,150 | 47,215,116 | 35,385,582 |
Cash Flow 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $36.0K | $566.0K | $678.0K | $80.0K | $99.0K | $101.0K | $98.0K | $101.0K | $99.0K | $99.0K | $113.0K | $130.0K | $136.0K | $177.0K | $203.0K | $201.0K | |
| Stock-based Comp | $24M | $48.0K | $610.0K | $2M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Operating Cash Flow | $-29M | $-11M | $-1M | $-9M | $-3M | $-8M | $-9M | $-8M | $-10M | $-10M | $-11M | $-8M | $-10M | $-11M | $-11M | $-7M | |
| CapEx | $0 | $121.0K | $0 | $0 | $27.0K | $150.0K | $2.0K | $-1.0K | $10.0K | $55.0K | $0 | $0 | $0 | $0 | $1.0K | $78.0K | |
| Investing Cash Flow | $0 | $-121.0K | $7M | $-7M | $-27.0K | $-150.0K | $-1.0K | $98.0K | $-10.0K | $-55.0K | $0 | $5M | $5M | $15M | $5M | $-30M | |
| Stock Issued | · | · | $10M | $0 | · | · | $-8.0K | $11M | · | · | · | · | · | · | · | · | |
| Stock Repurchased | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $9.0K | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | · | · | |
| Financing Cash Flow | $30M | $306.0K | $9M | $1.0K | $18M | $-1M | $-932.0K | $10M | $-1M | $2M | $5M | $5M | $2M | $388.0K | $27M | $-9.0K | |
| Net Change in Cash | $1M | $-11M | $15M | $-16M | $14M | $-9M | $-10M | $2M | $-11M | $-7M | $-6M | $2M | $-3M | $5M | $22M | $-36M | |
| Free Cash Flow | · | $-11M | · | · | · | $-8M | · | · | · | $-10M | · | · | · | $-11M | · | · |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1113.3% | -94.1% | · | -353.4% | -292.3% | -2921.4% | · | -264.2% | -390.6% | -737.8% | · | -543.8% | -978.1% | -7155.1% | · | -16222.1% | |
| Net Margin | -1943.2% | -91.1% | · | -346.6% | -287.1% | -2911.4% | · | -259.6% | -382.7% | -719.1% | · | -524.0% | -954.0% | -7010.2% | · | -16110.3% | |
| EBITDA Margin | -1113.3% | -94.1% | · | -353.4% | -292.3% | -2921.4% | · | -264.2% | -390.6% | -737.8% | · | -543.8% | -978.1% | -7155.1% | · | -16222.1% | |
| ROA | -428.7% | -19.5% | · | -19.5% | -20.4% | -32.2% | · | -15.2% | -17.6% | -18.2% | · | -15.2% | -16.7% | -15.2% | · | -14.1% | |
| ROE | -1495.6% | -36.7% | · | -38.6% | -42.6% | -67.0% | · | -25.5% | -30.1% | -29.0% | · | -23.6% | -24.9% | -21.9% | · | -19.2% |
Liquidity & Solvency 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.3 | 3.6 | · | 1.7 | 1.6 | 1.0 | · | 2.2 | 2.1 | 2.5 | · | 3.3 | 3.7 | 5.0 | · | 6.0 | |
| Quick Ratio | 1.1 | 2.9 | · | 0.8 | 1.5 | 0.8 | · | 2.1 | 1.9 | 2.3 | · | 3.3 | 3.3 | 4.1 | · | 3.0 | |
| Debt / Equity | · | · | · | · | · | 0.0 | · | 0.2 | 0.3 | 0.2 | · | 0.2 | 0.2 | 0.2 | · | 0.2 | |
| LT Debt / Equity | · | · | · | · | · | · | · | 0.1 | 0.1 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.2 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -383.9 | · | -45.0 | -38.6 | -40.5 | · | -89.0 |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.2 | · | 0.1 | 0.1 | 0.0 | · | 0.1 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | 2.7 | 2.1 | · | 1.2 | 2.5 | 0.6 | · | 1.4 | 1.8 | 2.2 | · | 1.7 | 1.5 | 0.3 | · | 0.1 |
Valuation (TTM) 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $19M | $11M | · | $9M | $9M | $8M | · | $10M | $8M | $5M | · | $4M | $2M | $1M | · | $3M | |
| Net Income TTM | $-174M | $-33M | · | $-37M | $-40M | $-43M | · | $-42M | $-47M | $-50M | · | $-48M | $-50M | $-52M | · | $-51M | |
| Market Cap | $165M | $748.7K | · | $56M | $52M | $56M | · | $46M | $60M | $92M | · | $104M | $160M | $154M | · | $79M | |
| Enterprise Value | · | · | · | · | · | $43M | · | $18M | $37M | $58M | · | $58M | $117M | $108M | · | $59M | |
| P/E | -1.1 | -0.0 | · | -1.4 | -1.1 | -1.2 | · | -0.9 | -1.3 | -1.8 | · | -2.0 | -2.9 | -2.5 | · | -1.5 | |
| P/S | 8.8 | 0.1 | · | 6.3 | 5.6 | 6.9 | · | 4.6 | 7.7 | 17.1 | · | 27.8 | 96.0 | 120.3 | · | 22.6 | |
| P/B | 71.4 | 0.0 | · | 4.2 | 2.9 | 8.6 | · | 1.8 | 2.8 | 3.1 | · | 2.4 | 3.5 | 2.8 | · | 1.6 | |
| P / Tangible Book | 71.4 | 0.0 | · | 4.2 | 2.9 | 8.6 | · | 1.8 | 2.8 | 3.1 | · | 2.4 | 3.5 | 2.8 | · | 1.6 | |
| P / Cash Flow | · | -0.1 | · | · | · | -6.9 | · | · | · | -9.4 | · | · | · | -14.2 | · | · | |
| P / FCF | · | -0.1 | · | · | · | -6.8 | · | · | · | -9.3 | · | · | · | -14.2 | · | · | |
| EV / EBITDA | · | · | · | · | · | -3.5 | · | -2.1 | -3.5 | -4.6 | · | -5.1 | -8.6 | -8.1 | · | -5.4 | |
| EV / FCF | · | · | · | · | · | -5.2 | · | · | · | -5.9 | · | · | · | -10.0 | · | · | |
| EV / Revenue | · | · | · | · | · | 5.3 | · | 1.9 | 4.7 | 10.8 | · | 15.6 | 70.3 | 84.2 | · | 17.0 | |
| Earnings Yield | -88.6% | -2691.3% | · | -69.5% | -92.4% | -86.7% | · | -113.6% | -79.0% | -56.6% | · | -49.1% | -34.5% | -39.5% | · | -68.6% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $27M | $9M | $5M | $1M | $15M |
| Operating Margin % | -96.7% | -446.9% | -949.9% | -4274.3% | -292.6% |
| Net Income | $-27M | $-41M | $-51M | $-53M | $-44M |
| Diluted EPS | $-0.28 | $-0.72 | $-1.11 | $-1.49 | $-1.41 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debt / Equity | — | 0.0 | 0.2 | 0.2 | — |
| Current Ratio | 2.7 | 1.8 | 3.0 | 6.7 | 5.4 |
| Quick Ratio | 2.4 | 1.7 | 2.9 | 4.5 | 5.3 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-22M | $-36M | $-40M | $-42M | $-40M |
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Institutional owners (13F) 4 filers · $754K total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 0 | 50 | 0 | 0 | — |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair. Change vs prior quarter not shown: filer coverage differs too much between these two quarters for a reliable comparison.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD GROUP INC | $749,523 | 2,457,452 | 99.45% | Shares |
| Beacon Pointe Advisors, LLC | $2,299 | 10,000 | 0.31% | Shares |
| New Millennium Group LLC | $1,756 | 5,750 | 0.23% | Shares |
| IFP Advisors, Inc | $55 | 100 | 0.01% | Shares |
Company insiders 35 insiders · 15 officers · 18 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Usman Azam | CHIEF EXECUTIVE OFFICER | Sept. 29, 2025 A | — | 0 | 0 | $0 |
| Daniel R Passeri | CHIEF EXECUTIVE OFFICER | March 21, 2025 A | 164,578 | 0 | 0 | $0 |
| James M Ahlers | Chief Financial Officer | July 30, 2026 A | 25,500 | 0 | 0 | $0 |
| Kerri-Ann Millar | CHIEF FINANCIAL OFFICER | March 21, 2025 A | 14,311 | 0 | 0 | $0 |
| Anish Suri | PRESIDENT AND CSO | June 5, 2024 A | 135,638 | 0 | 0 | $0 |
| Dominique Christian Borie | Chief Medical Officer | July 13, 2026 A | 31,500 | 0 | 0 | $0 |
| Daniel G. Baker | CHIEF DEVELOPMENT OFFICER | April 9, 2026 A | — | 0 | 0 | $0 |
| Lucinda Warren | CHIEF BUSINESS OFFICER | April 9, 2026 A | — | 0 | 0 | $0 |
| Colin Sandercock | SVP, GENERAL COUNSEL | April 9, 2026 A | 17,125 | 0 | 0 | $0 |
| Matteo Levisetti | Chief Medical Officer | March 21, 2025 A | — | 0 | 0 | $0 |
| Patricia Nasshorn | Chief Business Officer | Feb. 16, 2023 A | — | 0 | 0 | $0 |
| Kenneth Pienta | Chief Medical Officer | March 25, 2022 A | 2,000 | 0 | 0 | $0 |
| Bethany Mancilla | SVP and Chief Business Officer | March 6, 2019 A | — | 0 | 0 | $0 |
| Ronald D. Seidel III | EVP, Head of R&D | July 23, 2018 A | — | 0 | 0 | $0 |
| Rodolfo Chaparro | EVP, Head of Immunology | July 23, 2018 A | — | 0 | 0 | $0 |
| Viola Mong Meehan | Director | July 9, 2026 A | 21,800 | 0 | 0 | $0 |
| Pasha Sarraf | Director | July 9, 2026 A | 32,595 | 5 | 0 | $99,719 |
| Pamela Garzone | Director | July 9, 2026 A | 21,800 | 0 | 0 | $0 |
| Daniel A. Camardo | Director | July 9, 2026 A | 21,800 | 0 | 0 | $0 |
| Patrick Verheyen | Director | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| Frank Morich | Director | Jan. 2, 2026 A | 28,000 | 0 | 0 | $0 |
| Peter A Kiener | Director | Jan. 2, 2026 A | 357 | 0 | 0 | $0 |
| Jill Marie Broadfoot | Director | Jan. 2, 2026 A | — | 0 | 0 | $0 |
| Frederick W Driscoll | Director | Jan. 2, 2025 A | — | 0 | 0 | $0 |
| Michael J Fox | Director | June 5, 2024 A | — | 0 | 0 | $0 |
| Fletcher Aaron G.L. | Director | Jan. 3, 2023 A | 940,000 | 0 | 0 | $0 |
| Tamar D Howson | Director | Jan. 3, 2023 A | — | 0 | 0 | $0 |
| Cameron Gray | Director | June 14, 2022 X | 687,049 | 0 | 0 | $0 |
| Steven L Mcknight | Director | Jan. 2, 2020 A | — | 0 | 0 | $0 |
| Christopher A Marlett | Director | Jan. 2, 2020 A | 0 | 0 | 0 | $0 |
| Anthony DiGiandomenico | Director | Dec. 24, 2018 P | 30,000 | 0 | 0 | $0 |
| Michael Vincent Meluzio | — | Aug. 13, 2026 M | 48,961 | 0 | 3 | $-169,323 |
| Sumita Ray | — | Aug. 13, 2026 M | 118,545 | 0 | 3 | $-265,629 |
| Shao-Lee Lin | — | Aug. 12, 2026 M | 705,995 | 0 | 5 | $-1,606,562 |
| Barry J. Simon | — | Jan. 4, 2021 A | — | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Christopher A. Marlett 2) ×2 filings | April 21, 2020 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 3 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.