ALEC Alector, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$2.16
Price · Aug 18, 2026
Fundamentals as of Aug 6, 2026

About Alector, Inc. - Common Stock Company overview from Wikipedia

ALEC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$2.15
Market Cap
$239M
P/E (TTM)
-1.6
EPS (TTM)
$-1.39
Revenue (TTM)
$21M
Div Yield
ROE
-280.7%
Debt/Equity
0.3
52W Range
$1 – $3

ALEC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $21M
9-point trend, +463.5%
2017-12-31 2025-12-31
EPS $-1.39
6-point trend, +43.3%
2020-12-31 2025-12-31
Free Cash Flow $-184M
6-point trend, -60.7%
2019-12-31 2025-12-31
Margins -679.2%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ALEC
Peer Median
P/E (TTM)
5-point trend, +97.6%
-1.6
P/S (TTM)
5-point trend, +3.4%
11.4
10.0
P/B
5-point trend, +3.1%
7.8
4.7
EV / EBITDA
2-point trend, -68.2%
0.0
Price / FCF
5-point trend, -116.9%
-1.3

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ALEC
Peer Median
Operating Margin
5-point trend, -4009.2%
-741.3%
Net Profit Margin
5-point trend, -3772.1%
-679.2%
-287.1%
ROA
5-point trend, -572.8%
-37.5%
-74.0%
ROE
5-point trend, -2360.5%
-280.7%
-120.4%
ROIC
2-point trend, -263.3%
-387.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ALEC
Peer Median
Debt / Equity
2-point trend, +327.2%
0.3
Current Ratio
5-point trend, -28.6%
3.8
6.6
Quick Ratio
5-point trend, -30.1%
3.7

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ALEC
Peer Median
Revenue YoY
5-point trend, -89.8%
-79.1%
Revenue CAGR 3Y
5-point trend, -89.8%
-46.0%
Revenue CAGR 5Y
5-point trend, -89.8%
-0.05%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ALEC
Peer Median
EPS (Diluted)
5-point trend, -208.9%
$-1.39

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ALEC
Peer Median

ALEC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 14 analysts
  • Strong Buy 3 21.4%
  • Buy 5 35.7%
  • Hold 4 28.6%
  • Sell 2 14.3%
  • Strong Sell 0 0.0%

12-Month Price Target

5 analysts · 2026-08-14
Median target $2.00 -7.2%
Mean target $3.10 +43.9%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.09%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.21 $-0.23 0.02%
March 31, 2026 $-0.21 $-0.35 0.14%
Dec. 31, 2025 $-0.34 $-0.39 0.05%
Sept. 30, 2025 $-0.34 $-0.42 0.08%
June 30, 2025 $-0.30 $-0.47 0.17%
March 31, 2025 $-0.41 $-0.49 0.08%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ALEC $172M -1.1 -79.1% -679.2% -280.7%
GLSI $300M -14.7 -2159.7%
PYXS $72M -0.9 -14.2% -574.5% -112.9%
RCEL $105M -2.0 11.5% -67.8% 328.9% 82.1%
TARA $286M -4.0 -33.7%
AKBA $427M -80.5 47.5% -2.3% -17.3%
EBS $644M 13.3 -28.8% 7.1% 9.9%
ARCT $174M -2.6 -46.1% -80.2% -29.6%
NBP
IMUX -0.9
ORGO $658M 34.5 17.0% 6.6% 13.9%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for ALEC
Metric Trend 20252024202320222021202020192018
Revenue 8-point trend, -24.0% $21M $101M $97M $134M $207M $21M $21M $28M
R&D Expense 8-point trend, +68.5% $123M $186M $192M $210M $189M $157M $101M $73M
SG&A Expense 8-point trend, +352.4% $54M $60M $57M $61M $55M $59M $35M $12M
Operating Expenses 8-point trend, +108.4% $177M $246M $249M $271M $244M $216M $136M $85M
Operating Income 8-point trend, -172.3% $-156M $-145M $-152M $-138M $-37M $-195M $-114M $-57M
Other Non-op 8-point trend, +162.8% $13M $26M $27M $8M $1M $5M $9M $5M
Pretax Income 4-point trend, -9.7% $-143M $-119M $-125M $-130M · · · ·
Income Tax 7-point trend, +168000.00 $168.0K $128.0K $5M $3M $0 $0 $0 ·
Net Income 8-point trend, -173.6% $-143M $-119M $-130M $-133M $-36M $-190M $-105M $-52M
EPS (Basic) 6-point trend, +43.3% $-1.39 $-1.23 $-1.56 $-1.62 $-0.45 $-2.45 · ·
EPS (Diluted) 6-point trend, +43.3% $-1.39 $-1.23 $-1.56 $-1.62 $-0.45 $-2.45 · ·
Shares (Basic) 6-point trend, +32.5% 102,998,978 96,588,177 83,733,730 82,467,587 80,416,936 77,758,806 · ·
Shares (Diluted) 6-point trend, +32.5% 102,998,978 96,588,177 83,733,730 82,467,587 80,416,936 77,758,806 · ·
EBITDA 6-point trend, -36.4% $-156M $-145M $-152M $-138M $-37M · $-114M ·
Balance Sheet 25
Annual Balance Sheet data for ALEC
Metric Trend 20252024202320222021202020192018
Cash & Equivalents 8-point trend, +0.5% $66M $33M $75M $154M $329M $50M $90M $65M
Short-term Investments 8-point trend, -15.4% $190M $380M $474M $559M $406M $363M $263M $225M
Prepaid Expense 8-point trend, +276.7% $10M $11M $17M $11M $7M $8M $4M $3M
Current Assets 8-point trend, -9.1% $266M $425M $566M $726M $750M $422M $357M $293M
PP&E (Net) 8-point trend, -0.9% $11M $17M $22M $26M $27M $30M $34M $11M
PP&E (Gross) 8-point trend, +276.5% $48M $50M $50M $48M $45M $41M $39M $13M
Accum. Depreciation 8-point trend, +1872.3% $37M $33M $28M $23M $17M $11M $5M $2M
Other Non-current Assets 8-point trend, -86.1% $386.0K $5M $7M $6M $6M $3M $676.0K $3M
Total Assets 8-point trend, -4.9% $293M $468M $622M $788M $815M $488M $422M $308M
Accounts Payable 8-point trend, +1242.1% $2M $2M $4M $4M $5M $3M $278.0K $126.0K
Accrued Liabilities 8-point trend, +128.7% $19M $29M $30M $28M $27M $23M $18M $8M
Short-term Debt 2-point trend, +366000.00 $366.0K $0 · · · · · ·
Current Liabilities 8-point trend, +45.0% $70M $125M $178M $94M $140M $68M $62M $48M
Capital Leases 7-point trend, -57.8% $17M $24M $30M $35M $40M $44M $41M ·
Other Non-current Liabilities 8-point trend, +1709.4% $2M $1M $1M $759.0K $158.0K $472.0K $493.0K $96.0K
Total Liabilities 8-point trend, +34.5% $263M $342M $488M $573M $514M $221M $227M $195M
Long-term Debt Flat — no change across 2 periods $10M $10M · · · · · ·
Total Debt 2-point trend, +3.2% $10M $9M · · · · · ·
Common Stock 8-point trend, +1000.0% $11.0K $9.0K $8.0K $8.0K $8.0K $8.0K $7.0K $1.0K
Paid-in Capital 8-point trend, +5770.3% $1.00B $956M $844M $799M $748M $677M $414M $17M
Retained Earnings 8-point trend, -749.4% $-972M $-829M $-710M $-580M $-446M $-410M $-220M $-114M
AOCI 8-point trend, +495.2% $166.0K $261.0K $184.0K $-5M $-943.0K $614.0K $142.0K $-42.0K
Stockholders' Equity 8-point trend, +131.5% $31M $127M $134M $214M $301M $268M $195M $-97M
Liabilities + Equity 8-point trend, -4.9% $293M $468M $622M $788M $815M $488M $422M $308M
Shares Outstanding 8-point trend, +701.8% 110,362,581 99,085,888 84,879,693 82,895,718 81,986,192 79,316,261 69,052,873 13,764,829
Cash Flow 12
Annual Cash Flow data for ALEC
Metric Trend 20252024202320222021202020192018
D&A 8-point trend, +461.1% $6M $5M $6M $6M $6M $6M $4M $1M
Stock-based Comp 8-point trend, +285.0% $27M $39M $43M $46M $41M $31M $16M $7M
Restructuring 3-point trend, +35.3% $2M $4M $2M · · · · ·
Operating Cash Flow 8-point trend, -244.4% $-184M $-230M $-184M $-20M $299M $-167M $-99M $127M
CapEx 8-point trend, -97.8% $41.0K $1M $2M $4M $3M $5M $15M $2M
Investing Cash Flow 8-point trend, +187.7% $197M $107M $102M $-159M $-50M $-105M $-49M $-224M
Stock Issued 2-point trend, -71.9% $20M $71M · · · · · ·
Net Stock Activity $20M · · · · · · ·
Financing Cash Flow 8-point trend, -84.6% $20M $82M $3M $5M $30M $232M $172M $131M
Net Change in Cash 8-point trend, -5.0% $33M $-41M $-80M $-175M $279M $-40M $24M $34M
Taxes Paid 2-point trend, -780.0% $-880.0K $-100.0K · · · · · ·
Free Cash Flow 6-point trend, -60.7% $-184M $-231M $-187M $-24M $295M · $-115M ·
Profitability 7
Annual Profitability data for ALEC
Metric Trend 20252024202320222021202020192018
Operating Margin 6-point trend, -37.5% -741.3% -144.1% -156.3% -103.2% -18.0% · -539.2% ·
Net Margin 6-point trend, -36.7% -679.2% -118.3% -134.3% -99.8% -17.5% · -496.6% ·
Pretax Margin 2-point trend, -474.0% -678.4% -118.2% · · · · · ·
EBITDA Margin 6-point trend, -37.5% -741.3% -144.1% -156.3% -103.2% -18.0% · -539.2% ·
ROA 6-point trend, -30.1% -37.5% -21.8% -18.5% -16.6% -5.6% · -28.9% ·
ROE 6-point trend, -450.6% -280.7% -96.9% -87.9% -57.0% -11.4% · -51.0% ·
ROIC 2-point trend, -263.3% -387.2% -106.6% · · · · · ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for ALEC
Metric Trend 20252024202320222021202020192018
Current Ratio 6-point trend, -33.5% 3.8 3.4 3.2 7.7 5.4 · 5.8 ·
Quick Ratio 6-point trend, -35.3% 3.7 3.3 3.1 7.6 5.3 · 5.7 ·
Debt / Equity 2-point trend, +327.2% 0.3 0.1 · · · · · ·
LT Debt / Equity 2-point trend, +311.1% 0.3 0.1 · · · · · ·
Efficiency 1
Annual Efficiency data for ALEC
Metric Trend 20252024202320222021202020192018
Asset Turnover 6-point trend, -4.8% 0.1 0.2 0.1 0.2 0.3 · 0.1 ·
Per Share 5
Annual Per Share data for ALEC
Metric Trend 20252024202320222021202020192018
Book Value / Share 6-point trend, -90.2% $0.28 $1.28 $1.58 $2.62 $3.79 · $2.82 ·
Revenue / Share 4-point trend, -87.4% $0.20 $1.04 $1.16 $1.62 · · · ·
Cash Flow / Share 4-point trend, -624.8% $-1.79 $-2.38 $-2.20 $-0.25 · · · ·
Cash / Share 6-point trend, -54.1% $0.60 $0.33 $0.88 $1.88 $4.15 · $1.30 ·
EPS (TTM) 6-point trend, +43.3% $-1.39 $-1.23 $-1.56 $-1.62 $-0.45 $-2.45 · ·
Growth Rates 3
Annual Growth Rates data for ALEC
Metric Trend 20252024202320222021202020192018
Revenue YoY 5-point trend, -109.0% -79.1% 3.6% -27.3% -35.5% 881.5% · · ·
Revenue CAGR 3Y 3-point trend, -169.3% -46.0% -21.4% 66.3% · · · · ·
Revenue CAGR 5Y -0.05% · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for ALEC
Metric Trend 20252024202320222021202020192018
Revenue TTM 8-point trend, -24.0% $21M $101M $97M $134M $207M $21M $21M $28M
Net Income TTM 8-point trend, -173.6% $-143M $-119M $-130M $-133M $-36M $-190M $-105M $-52M
Market Cap 6-point trend, -85.5% $172M $187M $677M $757M $1.64B · $1.19B ·
Enterprise Value 2-point trend, +65.8% $-74M $-217M · · · · · ·
P/E 6-point trend, +81.8% -1.1 -1.5 -5.1 -5.7 -45.9 -6.2 · ·
P/S 6-point trend, -85.4% 8.2 1.9 7.0 5.7 7.9 · 56.1 ·
P/B 6-point trend, -8.1% 5.6 1.5 5.0 3.5 5.4 · 6.1 ·
P / Tangible Book 6-point trend, +25.2% 5.6 1.5 5.0 3.5 5.4 4.5 · ·
P / Cash Flow 6-point trend, +92.2% -0.9 -0.8 -3.7 -37.2 5.5 · -12.0 ·
P / FCF 6-point trend, +91.0% -0.9 -0.8 -3.6 -31.0 5.5 · -10.4 ·
EV / EBITDA 2-point trend, -68.2% 0.5 1.5 · · · · · ·
EV / FCF 2-point trend, -57.0% 0.4 0.9 · · · · · ·
EV / Revenue 2-point trend, -63.5% -3.5 -2.2 · · · · · ·
Earnings Yield 6-point trend, -450.3% -89.1% -65.1% -19.6% -17.5% -2.2% -16.2% · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $21M$101M$97M$134M$207M
Operating Margin % -741.3%-144.1%-156.3%-103.2%-18.0%
Net Income $-143M$-119M$-130M$-133M$-36M
Diluted EPS $-1.39$-1.23$-1.56$-1.62$-0.45
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.30.1
Current Ratio 3.83.43.27.75.4
Quick Ratio 3.73.33.17.65.3
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-184M$-231M$-187M$-24M$295M

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Institutional owners (13F) 156 filers · $158.2M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
24 (-1 vs prior Q) 8 (-10 vs prior Q) 55 (+15 vs prior Q) 33 (-5 vs prior Q) +10.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
TCG Crossover Management, LLC $20,100,000 10,000,000 12.70% Shares
VANGUARD GROUP INC $9,832,137 6,302,652 6.21% Shares
Nantahala Capital Management, LLC $8,679,399 4,318,109 5.49% Shares
VANGUARD CAPITAL MANAGEMENT LLC $8,058,773 4,009,340 5.09% Shares
Kynam Capital Management, LP $7,655,073 3,808,494 4.84% Shares
Merck & Co., Inc. $7,126,896 3,545,719 4.50% Shares
Balyasny Asset Management L.P. $6,527,326 3,247,426 4.13% Shares
683 Capital Management, LLC $6,432,000 3,200,000 4.07% Shares
ADAR1 Capital Management, LLC $5,796,002 2,883,583 3.66% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $5,669,191 2,820,493 3.58% Shares
GEODE CAPITAL MANAGEMENT, LLC $4,223,305 2,100,653 2.67% Shares
Spruce Street Capital LP $4,223,147 2,101,068 2.67% Shares
MILLENNIUM MANAGEMENT LLC $3,997,558 1,988,835 2.53% Shares
Ikarian Capital, LLC $3,985,038 1,982,606 2.52% Shares
STATE STREET CORP $3,778,328 1,879,765 2.39% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $3,549,517 1,765,929 2.24% Shares
MEDICI CAPITAL LLC $3,321,565 1,652,520 2.10% Shares
Affinity Asset Advisors, LLC $3,035,100 1,510,000 1.92% Shares
Eversept Partners, LP $2,861,985 1,423,873 1.81% Shares
FMR LLC $2,806,016 1,396,028 1.77% Shares
Euclidean Capital LLC $2,628,795 1,307,858 1.66% Shares
MACKENZIE FINANCIAL CORP $2,230,638 1,109,770 1.41% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $2,120,936 1,055,192 1.34% Shares
TWO SIGMA INVESTMENTS, LP $2,101,206 1,045,376 1.33% Shares
RENAISSANCE TECHNOLOGIES LLC $1,879,684 935,166 1.19% Shares
DAFNA Capital Management LLC $1,825,786 908,351 1.15% Shares
Elmind Capital, LP $1,809,000 900,000 1.14% Shares
PANAGORA ASSET MANAGEMENT INC $1,700,458 845,999 1.07% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,645,850 818,831 1.04% Shares
VANGUARD FIDUCIARY TRUST CO $1,333,820 663,592 0.84% Shares
BOOTHBAY FUND MANAGEMENT, LLC $1,071,029 532,850 0.68% Shares
TWO SIGMA ADVISERS, LP $1,016,808 651,800 0.64% Shares
D. E. Shaw & Co., Inc. $1,015,669 505,308 0.64% Shares
Balyasny Asset Management L.P. $1,012,839 503,900 0.64% Call option
New Leaf Venture Partners, L.L.C. $1,005,124 339,569 0.64% Shares
BlackRock, Inc. $942,989 469,149 0.60% Shares
XTX Topco Ltd $803,359 399,681 0.51% Shares
CITADEL ADVISORS LLC $643,051 319,926 0.41% Shares
CANTOR FITZGERALD, L. P. $593,939 295,492 0.38% Shares
GOLDMAN SACHS GROUP INC $551,379 274,318 0.35% Shares
UBS Group AG $550,298 273,780 0.35% Shares
AMERIPRISE FINANCIAL INC $451,305 224,530 0.29% Shares
NANO CAP NEW MILLENNIUM GROWTH FUND L P $402,000 200,000 0.25% Shares
LMR Partners LLP $402,000 200,000 0.25% Shares
Utah Retirement Systems $310,123 154,290 0.20% Shares
Cubist Systematic Strategies, LLC $296,197 100,067 0.19% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $286,425 142,500 0.18% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $273,159 135,900 0.17% Call option
CANADA PENSION PLAN INVESTMENT BOARD $263,913 131,300 0.17% Shares
JANE STREET GROUP, LLC $241,401 120,100 0.15% Call option
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO $240,736 119,769 0.15% Shares
ALLIANCEBERNSTEIN L.P. $234,221 108,940 0.15% Shares
RHUMBLINE ADVISERS $220,149 109,532 0.14% Shares
CITADEL ADVISORS LLC $218,889 108,900 0.14% Put option
STRS OHIO $204,216 101,600 0.13% Shares
BANK OF AMERICA CORP /DE/ $185,720 92,398 0.12% Shares
WELLS FARGO & COMPANY/MN $178,317 88,715 0.11% Shares
SIMPLEX TRADING, LLC $171,830 85,488 0.11% Shares
Bank of New York Mellon Corp $163,160 81,174 0.10% Shares
Blackstone Inc. $155,061 77,145 0.10% Shares
Jasper Ridge Partners, L.P. $147,797 73,531 0.09% Shares
SEI INVESTMENTS CO $143,014 71,151 0.09% Shares
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main $140,028 69,666 0.09% Shares
IEQ CAPITAL, LLC $121,746 60,570 0.08% Shares
Verdad Advisers, LP $121,623 60,509 0.08% Shares
MetLife Investment Management, LLC $117,979 58,696 0.07% Shares
Mariner, LLC $105,955 52,709 0.07% Shares
Vanguard Personalized Indexing Management, LLC $99,384 49,445 0.06% Shares
HSBC HOLDINGS PLC $98,016 48,523 0.06% Shares
Graham Capital Management, L.P. $93,457 46,496 0.06% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $90,832 45,190 0.06% Shares
MARSHALL WACE, LLP $86,820 43,194 0.05% Shares
DIVERSIFIED TRUST CO $85,125 42,351 0.05% Shares
JPMORGAN CHASE & CO $84,656 40,700 0.05% Shares
BARCLAYS PLC $83,047 41,317 0.05% Shares
CITIGROUP INC $80,884 40,241 0.05% Shares
Invesco Ltd. $77,960 38,786 0.05% Shares
Vanguard Global Advisers, LLC $62,917 31,302 0.04% Shares
CWM, LLC $62,318 28,985 0.04% Shares
Cannell & Spears LLC $60,987 30,342 0.04% Shares
Vontobel Holding Ltd. $60,300 30,000 0.04% Shares
Cerity Partners LLC $55,650 27,687 0.04% Shares
Point72 Asset Management, L.P. $53,665 26,699 0.03% Shares
MERCER GLOBAL ADVISORS INC /ADV $51,263 25,504 0.03% Shares
GROUP ONE TRADING LLC $50,668 25,208 0.03% Shares
INTECH INVESTMENT MANAGEMENT LLC $49,305 24,530 0.03% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $48,704 30,251 0.03% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $48,487 24,123 0.03% Shares
Police & Firemen's Retirement System of New Jersey $47,086 23,426 0.03% Shares
VOYA INVESTMENT MANAGEMENT LLC $44,015 21,898 0.03% Shares
BNP PARIBAS FINANCIAL MARKETS $42,612 21,200 0.03% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $38,988 19,397 0.02% Shares
DIMENSIONAL FUND ADVISORS LP $37,422 18,618 0.02% Shares
Qube Research & Technologies Ltd $33,304 16,569 0.02% Shares
CAPTRUST FINANCIAL ADVISORS $32,234 16,037 0.02% Shares
PRUDENTIAL FINANCIAL INC $32,190 16,015 0.02% Shares
NORTHERN TRUST CORP $30,813 15,330 0.02% Shares
Creative Planning $30,180 15,015 0.02% Shares
Tower Research Capital LLC (TRC) $29,044 14,450 0.02% Shares
Point72 (DIFC) Ltd $29,030 9,807 0.02% Shares

Company insiders 22 insiders · 11 officers · 12 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Arnon Rosenthal Chief Executive Officer June 2, 2026 S 2,367,206 0 1 $-171,816
Neil Lindsay Berkley CFO & Chief Business Officer June 2, 2026 S 379,900 0 1 $-38,139
Marc Grasso Chief Financial Officer March 3, 2025 S 312,560 0 0 $0
Sara Kenkare-Mitra President and Head of R&D July 1, 2025 A 566,977 0 0 $0
Shehnaaz Suliman President and COO Dec. 13, 2021 M 102,598 0 0 $0
Grace Wong-Sarad Principal Accounting Officer July 9, 2026 A 115,461 0 5 $-35,451
Gary Romano Chief Medical Officer March 3, 2025 S 332,977 0 0 $0
Robert King Chief Development Officer Oct. 1, 2022 A 550,871 0 0 $0
Robert Paul Chief Medical Officer Aug. 9, 2021 M 234,319 0 0 $0
Calvin Yu Vice President, Finance July 6, 2021 M 76,686 0 0 $0
Sabah Oney Chief Business Officer Oct. 1, 2020 A 573,918 0 0 $0
Elizabeth A. Garofalo Director June 17, 2026 A 118,650 0 0 $0
Paula Hammond Director June 17, 2026 A 103,609 0 0 $0
Kristine Yaffe Director June 17, 2026 A 124,109 0 0 $0
Mark Altmeyer Director June 17, 2026 A 98,650 0 0 $0
Richard H Scheller Director June 17, 2026 A 134,899 0 0 $0
Louis J Lavigne JR Director June 17, 2026 A 128,109 0 0 $0
Errol B Desouza Director June 17, 2026 A 98,650 0 0 $0
David M. Wehner Director June 12, 2024 A 115,330 0 0 $0
Terrance McGuire Director Sept. 11, 2023 S 10,853,817 0 0 $0
Tillman U. Gerngross Director June 14, 2023 A 2,644,319 0 0 $0
GORDON CARL L Director May 10, 2019 A 203,200 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
OrbiMed Advisors LLC, OrbiMed Capital GP IV LLC ×10 filings July 16, 2020 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 26 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
UAE · iShares Trust 0.45% 3,639,585 SH Aug. 8, 2026 Daily
QQQS · Invesco Exchange-Traded Fund Trust … 0.41% 51,769 SH Aug. 8, 2026 Daily
IBRN · iShares Trust 0.15% 6,349 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.04% 330,159 SH Aug. 8, 2026 Daily
EEMS · iShares, Inc. 0.02% 207,850 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 563,396 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 94,277 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.01% 801,009 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.01% 154,865 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.01% 2,496,592 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.00% 4,283 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.00% 441,696 NS May 31, 2026 N-PORT
UWM · ProShares Trust 0.00% 3,348 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 3,385 NS May 31, 2026 N-PORT
IWN · iShares Trust 0.00% 159,667 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 59,910 NS April 30, 2026 N-PORT
HDG · ProShares Trust 0.00% 85 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 2,341 NS May 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.00% 3,867 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 87,957 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 16,436 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 1,071,545 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,837,922 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 9,493 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 5,223 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.00% 230,061 SH Aug. 8, 2026 Daily