ELDN Eledon Pharmaceuticals, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$3.65
Price · Aug 19, 2026
Fundamentals as of Aug 13, 2026
52W Range
$1–$5
71% of range
Analyst Rating
BUY
12 analysts
Price Target
$9
+147% upside
P/E (TTM)
-7.0
ROE
-69.4%
Net Profit Margin
—

ELDN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$3.65
Market Cap
$275M
P/E (TTM)
-7.0
EPS (TTM)
$-0.52
Revenue (TTM)
—
Div Yield
—
ROE
-69.4%
Debt/Equity
—
52W Range
$1 – $5

ELDN Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income —
2016-12-31 → 2016-12-31
EPS $-0.52
5-point trend, +77.7%
2021-12-31 → 2025-12-31
Free Cash Flow —
Margins —

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ELDN
Peer Median
P/E (TTM)
5-point trend, -53.4%
-7.0
—
P/B
5-point trend, -90.2%
3.4
1.0

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ELDN
Peer Median
ROA
5-point trend, +77.0%
-26.3%
-40.4%
ROE
5-point trend, +50.5%
-69.4%
-43.7%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ELDN
Peer Median
Current Ratio
5-point trend, -1.9%
7.4
7.3
Quick Ratio
5-point trend, +9.3%
7.3
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ELDN
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ELDN
Peer Median
EPS (Diluted)
5-point trend, +77.7%
$-0.52
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ELDN
Peer Median

ELDN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 12 analysts
  • Strong Buy 4 33.3%
  • Buy 7 58.3%
  • Hold 1 8.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

5 analysts · 2026-08-19
Median target $8.00 +119.2%
Mean target $9.00 +146.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.22%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.33 $-0.19 -0.14%
Dec. 31, 2025 $-0.10 $-0.21 0.11%
Sept. 30, 2025 $-0.21 $-0.26 0.04%
June 30, 2025 $-0.13 $-0.23 0.10%
March 31, 2025 $-0.08 $-0.31 0.23%
Dec. 31, 2024 $0.67 $-0.32 0.99%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ELDN $114M -2.9 — — -69.4% —
VNDA $521M -2.4 8.7% -102.0% -54.2% —
CAMP $318M -2.3 436.5% -2298.5% -183.4% —
IRD $140M -2.5 29.1% -349.3% -302.2% —
AVXL $771M -16.5 -36.1% -991.4% -47.7% —
MYGN $575M -1.6 -1.6% -44.4% -96.8% 69.9%
ANIK $133M -12.6 -5.9% -9.6% -7.5% 56.6%
TRDA $394M -3.0 -87.9% -565.5% -41.9% —
RNAC $188M -1.4 -92.8% -4658.6% 202.4% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
Revenue Flat — no change across 3 periods · · · · · · · · · $0 $0 $0
R&D Expense 12-point trend, +354.6% $66M $52M $30M $27M $24M $6M $8M $7M $2M $3M $33M $15M
SG&A Expense 12-point trend, +91.2% $17M $19M $13M $13M $13M $10M $6M $7M $11M $2M $13M $9M
Operating Expenses 12-point trend, +254.8% $83M $71M $43M $88M $37M $18M $16M $14M $13M $5M $45M $23M
Operating Income 10-point trend, -83.3% · · $-43M $-88M $-37M $-18M $-16M $-14M $-13M $-5M $-45M $-23M
Other Non-op 11-point trend, +2442.2% $4M $4M $3M $462.0K $7.0K $79.0K $40.0K $-5.0K $5.0K $-527.0K · $166.0K
Pretax Income 10-point trend, -706.0% $-46M $-36M $-117M $-88M $-37M $-23M $-16M $-14M $-13M $-6M · ·
Income Tax 9-point trend, +35000.00 $35.0K $431.0K $0 $0 $-2M $-404.0K · · · $0 $0 $0
Net Income 12-point trend, -95.8% $-46M $-36M $-117M $-88M $-35M $-23M $-16M $-14M $-13M $-6M $-45M $-23M
EPS (Basic) 5-point trend, +77.7% $-0.52 $-0.66 $-4.73 $-6.16 $-2.33 · · · · · · ·
EPS (Diluted) 5-point trend, +77.7% $-0.52 $-0.66 $-4.73 $-6.16 $-2.33 · · · · · · ·
Shares (Basic) 5-point trend, +452.2% 81,836,246 48,543,787 24,619,197 14,285,254 14,819,582 · · · · · · ·
Shares (Diluted) 5-point trend, +452.2% 81,836,246 48,543,787 24,619,197 14,285,254 14,819,582 · · · · · · ·
EBITDA 7-point trend, -276.9% · · · $-88M $-37M $-18M $-16M · $-13M · $-45M $-23M
Balance Sheet 25
Annual Balance Sheet data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, -78.3% $23M $21M $5M $56M $85M $114M $9M $13M $17M $1M $24M $105M
Short-term Investments 4-point trend, +110528000.00 $111M $120M $46M $0 · · · · · · · ·
Prepaid Expense 12-point trend, +4.3% $2M $4M $5M $3M $4M $1M $1M $1M $2M $33.0K $3M $2M
Other Current Assets 10-point trend, -66.7% $11.0K $104.0K $90.0K $28.0K $34.0K $38.0K $54.0K $36.0K $18.0K $33.0K · ·
Current Assets 12-point trend, +26.2% $136M $144M $56M $60M $88M $116M $10M $14M $19M $1M $67M $108M
PP&E (Net) 6-point trend, -84.8% · · · · · · $5.0K $14.0K $25.0K $31.0K $489.0K $33.0K
PP&E (Gross) 3-point trend, +150.5% · · · · · · · · · $228.0K $654.0K $91.0K
Accum. Depreciation 3-point trend, +124.1% · · · · · · · · · $130.0K $165.0K $58.0K
Goodwill 6-point trend, -100.0% · · $0 $0 $49M $49M · $2M $2M · · ·
Other Non-current Assets 10-point trend, +615.6% $322.0K $363.0K $186.0K $150.0K $400.0K $383.0K $639.0K $869.0K · $15.0K $45.0K ·
Total Assets 12-point trend, +56.9% $169M $177M $89M $93M $171M $197M $11M $17M $21M $1M $68M $108M
Accounts Payable 12-point trend, +374.1% $4M $6M $967.0K $2M $2M $1M $329.0K $689.0K $418.0K $338.0K $1M $765.0K
Accrued Liabilities 3-point trend, -96.8% · · · · · · · · · $113.0K $5M $3M
Current Liabilities 11-point trend, +332.3% $18M $12M $4M $6M $4M $2M $1M $3M · $4M $6M $4M
Capital Leases 6-point trend, +96.5% $283.0K $640.0K $0 $383.0K $400.0K · $144.0K · · · · ·
Deferred Tax 6-point trend, -46.7% $2M $2M $2M $2M $2M $4M · · · · · ·
Other Non-current Liabilities · · · · · · · · · · $88.0K ·
Total Liabilities 12-point trend, +659.6% $32M $59M $82M $9M $7M $7M $1M $3M $1M $4M $6M $4M
Common Stock 12-point trend, +240.9% $75.0K $60.0K $24.0K $14.0K $14.0K $15.0K $1.0K $9.0K $7.0K $1.0K $23.0K $22.0K
Paid-in Capital · · · · · · · · · · · $190M
Retained Earnings 12-point trend, -364.6% $-401M $-356M $-319M $-203M $-115M $-80M $-58M $-42M $-28M $-14M $-131M $-86M
AOCI 4-point trend, +143.6% $24.0K $26.0K · · · · · · · $-1.0K $-55.0K ·
Stockholders' Equity 12-point trend, -21.7% $81M $62M $-48M $24M $164M $191M $9M $14M $19M $-3M $3M $104M
Liabilities + Equity 12-point trend, +56.9% $169M $177M $89M $93M $171M $197M $11M $17M $21M $1M $68M $108M
Shares Outstanding 12-point trend, +237.0% 75,430,033 59,789,275 24,213,130 13,776,788 14,306,788 15,160,397 720,408 9,422,143 7,110,414 394,306 22,597,144 22,382,340
Cash Flow 13
Annual Cash Flow data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
D&A 5-point trend, -85.7% · · · · · $5.0K $9.0K $11.0K $22.0K $35.0K · ·
Stock-based Comp · · · · · · · · · · · $2M
Deferred Tax 4-point trend, +101.2% $5.0K $431.0K · · $-2M $-404.0K · · · · · ·
Restructuring 2-point trend, +0.8% · · · · $2M $2M · · · · · ·
Operating Cash Flow 12-point trend, -195.2% $-62M $-47M $-40M $-28M $-29M $-15M $-14M $-12M $-15M $-5M $-41M $-21M
CapEx 3-point trend, -64.0% · · · · · · · · · $9.0K $565.0K $25.0K
Investing Cash Flow 5-point trend, -53.6% $11M $-70M $-45M · · $11M · · $23M · · ·
Stock Issued 4-point trend, +89.5% · · · · · $9M $10M $7M $5M · · ·
Net Stock Activity 3-point trend, +89.5% · · · · · $9M $10M · $5M · · ·
Financing Cash Flow 8-point trend, +583.8% $54M $134M $33M · $-449.0K $110M $10M $8M $8M · · ·
Net Change in Cash 12-point trend, -96.9% $2M $16M $-52M $-28M $-29M $105M $-4M $-4M $16M $-2M $-81M $74M
Taxes Paid $28.0K · · · · · · · · · · ·
Free Cash Flow 2-point trend, -97.7% · · · · · · · · · · $-42M $-21M
Profitability 3
Annual Profitability data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
ROA 8-point trend, +20.8% -26.3% · · -66.8% -18.8% -21.9% -114.5% · -118.8% · -51.3% -33.3%
ROE 8-point trend, +28.1% -69.4% · · -78.1% -20.6% -21.5% -140.3% · -156.6% · -54.6% -96.6%
ROIC 3-point trend, -1003.4% · · · -105.0% -21.0% -9.5% · · · · · ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 7-point trend, -70.8% 7.4 · · 9.2 20.1 46.6 7.5 · · · 10.9 25.3
Quick Ratio 7-point trend, -70.7% 7.3 · · 8.7 19.3 46.0 6.6 · · · 3.9 24.8
Efficiency 1
Annual Efficiency data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover Flat — no change across 2 periods · · · · · · · · · · 0.0 0.0
Per Share 4
Annual Per Share data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 8-point trend, -76.8% $1.07 · · $6.11 $11.46 $12.57 $0.73 · $2.74 · $2.73 $4.62
Cash Flow / Share 3-point trend, +61.7% $-0.76 · $-1.61 $-1.99 · · · · · · · ·
Cash / Share 8-point trend, -93.6% $0.30 · · $4.09 $5.93 $7.53 $0.68 · $2.42 · $1.06 $4.70
EPS (TTM) 5-point trend, +77.7% $-0.52 $-0.66 $-4.73 $-6.16 $-2.33 · · · · · · ·
Valuation (TTM) 9
Annual Valuation (TTM) data for ELDN
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM Flat — no change across 12 periods $0 $0 $0 $0 $0 $0 $0 $0 $0 $0 $0 $0
Net Income TTM 12-point trend, -95.8% $-46M $-36M $-117M $-88M $-35M $-23M $-16M $-14M $-13M $-6M $-45M $-23M
Market Cap 8-point trend, -99.8% $114M · · $31M $63M $233M $135M · $520M · $31.92B $53.45B
P/E 5-point trend, -53.4% -2.9 -6.2 -0.4 -0.4 -1.9 · · · · · · ·
P/B 8-point trend, -99.7% 1.4 · · 0.4 0.4 1.2 14.3 · 26.7 · 517.2 516.4
P / Tangible Book 5-point trend, -14.6% 1.4 3.9 · 1.3 0.5 1.6 · · · · · ·
P / Cash Flow 8-point trend, +99.9% -1.8 · · -1.1 -2.2 -15.3 -9.8 · -34.8 · -774.1 -2530.5
P / FCF 2-point trend, +69.8% · · · · · · · · · · -763.7 -2527.5
Earnings Yield 5-point trend, +34.8% -34.4% -16.0% -262.8% -270.2% -52.8% · · · · · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-46M$-36M$-117M$-88M$-35M
Diluted EPS $-0.52$-0.66$-4.73$-6.16$-2.33
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 7.4——9.220.1
Quick Ratio 7.3——8.719.3

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Institutional owners (13F) 171 filers · $146.2M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
57 (+18 vs prior Q) 9 (-5 vs prior Q) 54 (+21 vs prior Q) 26 (+5 vs prior Q) +5.9M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BVF INC/IL $24,795,531 6,293,282 16.97% Shares
Defilade Capital Management, L.P. $13,889,832 3,525,338 9.50% Shares
VANGUARD CAPITAL MANAGEMENT LLC $13,463,859 3,417,223 9.21% Shares
Ensign Peak Advisors, Inc $8,278,823 2,101,224 5.66% Shares
Catalio Capital Management, LP $6,678,580 1,695,071 4.57% Shares
GEODE CAPITAL MANAGEMENT, LLC $6,603,582 1,675,564 4.52% Shares
STATE STREET CORP $6,390,558 1,621,969 4.37% Shares
Zimmer Partners, LP $6,290,600 1,596,599 4.30% Shares
SPHERA FUNDS MANAGEMENT LTD. $4,693,277 1,191,187 3.21% Shares
AWM Investment Company, Inc. $4,334,000 1,100,000 2.97% Shares
KINGDON CAPITAL MANAGEMENT, L.L.C. $4,094,744 1,039,275 2.80% Shares
MILLENNIUM MANAGEMENT LLC $3,860,065 979,712 2.64% Shares
GOLDMAN SACHS GROUP INC $2,703,782 686,239 1.85% Shares
ADAR1 Capital Management, LLC $2,552,379 647,812 1.75% Shares
22NW, LP $2,507,274 636,364 1.72% Shares
CM Management, LLC $2,265,500 575,000 1.55% Shares
AQR CAPITAL MANAGEMENT LLC $2,245,264 569,864 1.54% Shares
Blue Owl Capital Holdings LP $2,232,045 566,509 1.53% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $2,101,458 533,365 1.44% Shares
VANGUARD FIDUCIARY TRUST CO $2,084,114 528,963 1.43% Shares
DIMENSIONAL FUND ADVISORS LP $1,837,624 466,402 1.26% Shares
Triumph Capital Management $1,195,565 303,443 0.82% Shares
Brevan Howard Capital Management LP $1,174,645 304,707 0.80% Shares
CITADEL ADVISORS LLC $1,100,836 279,400 0.75% Put option
JANE STREET GROUP, LLC $1,095,320 278,000 0.75% Put option
BIT Capital GmbH $1,048,040 266,000 0.72% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $993,794 252,232 0.68% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $978,302 248,300 0.67% Put option
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $974,772 247,404 0.67% Shares
CITADEL ADVISORS LLC $850,934 215,973 0.58% Shares
RENAISSANCE TECHNOLOGIES LLC $791,546 200,900 0.54% Shares
VANGUARD GROUP INC $680,989 450,986 0.47% Shares
LPL Financial LLC $440,078 111,695 0.30% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $432,774 109,841 0.30% Shares
Maven Securities LTD $394,000 100,000 0.27% Shares
BANK OF AMERICA CORP /DE/ $370,202 93,960 0.25% Shares
RHUMBLINE ADVISERS $349,112 88,609 0.24% Shares
SIMPLEX TRADING, LLC $349,072 88,597 0.24% Shares
Prodigy Asset Management LLC $341,610 86,703 0.23% Shares
Daytona Street Capital LLC $313,301 81,166 0.21% Shares
Rockefeller Capital Management L.P. $286,304 72,666 0.20% Shares
Susquehanna Portfolio Strategies, LLC $283,361 71,919 0.19% Shares
WELLS FARGO & COMPANY/MN $273,042 69,300 0.19% Shares
Shay Capital LLC $252,160 64,000 0.17% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $236,006 59,900 0.16% Call option
PW Nova Financial Services LLC $228,682 58,041 0.16% Shares
Mariner, LLC $197,149 50,041 0.13% Shares
IEQ CAPITAL, LLC $189,770 48,165 0.13% Shares
Bank of New York Mellon Corp $179,928 45,667 0.12% Shares
WOLVERINE TRADING, LLC $179,324 70,600 0.12% Put option
MetLife Investment Management, LLC $161,217 40,918 0.11% Shares
BlackRock, Inc. $160,468 40,728 0.11% Shares
Russell Investments Group, Ltd. $159,499 40,482 0.11% Shares
Kera Capital Partners, Inc. $158,420 40,208 0.11% Shares
WOLVERINE TRADING, LLC $151,318 59,574 0.10% Shares
XTX Topco Ltd $150,930 38,307 0.10% Shares
NAVELLIER & ASSOCIATES INC $141,545 35,925 0.10% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $139,764 35,473 0.10% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $133,268 34,615 0.09% Shares
MERCER GLOBAL ADVISORS INC /ADV $131,986 33,499 0.09% Shares
MORGAN STANLEY $131,718 33,431 0.09% Shares
TWO SIGMA INVESTMENTS, LP $129,803 32,945 0.09% Shares
CITIGROUP INC $124,634 31,633 0.09% Shares
JPMORGAN CHASE & CO $123,904 31,934 0.08% Shares
MARCO INVESTMENT MANAGEMENT LLC $119,555 30,344 0.08% Shares
Invesco Ltd. $119,500 30,330 0.08% Shares
Retirement Planning Group, LLC $118,204 30,001 0.08% Shares
HOWARD FINANCIAL SERVICES, LTD. $118,200 30,000 0.08% Shares
Cetera Investment Advisers $113,736 28,867 0.08% Shares
KESTRA PRIVATE WEALTH SERVICES, LLC $108,350 27,500 0.07% Shares
SEI INVESTMENTS CO $106,857 27,121 0.07% Shares
Nuveen, LLC $106,857 27,121 0.07% Shares
ALLIANCEBERNSTEIN L.P. $99,792 32,400 0.07% Shares
Vanguard Global Advisers, LLC $98,248 24,936 0.07% Shares
GROUP ONE TRADING LLC $97,416 24,725 0.07% Shares
Police & Firemen's Retirement System of New Jersey $92,622 23,508 0.06% Shares
Creative Planning $92,428 23,459 0.06% Shares
Scientech Research LLC $90,005 22,844 0.06% Shares
JANE STREET GROUP, LLC $88,173 22,379 0.06% Shares
Private Advisor Group, LLC $85,735 21,760 0.06% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $84,517 21,451 0.06% Shares
Jump Financial, LLC $83,847 21,281 0.06% Shares
INTECH INVESTMENT MANAGEMENT LLC $76,570 19,434 0.05% Shares
JONES FINANCIAL COMPANIES LLLP $75,419 19,952 0.05% Shares
Relyea Zuckerberg Hanson LLC $66,980 17,000 0.05% Shares
RAYMOND JAMES FINANCIAL INC $66,728 16,936 0.05% Shares
WELLINGTON MANAGEMENT GROUP LLP $65,841 16,711 0.05% Shares
COMMONWEALTH EQUITY SERVICES, LLC $65,230 16,556 0.04% Shares
Baker Ellis Asset Management LLC $63,040 16,000 0.04% Shares
China Universal Asset Management Co., Ltd. $63,040 16,000 0.04% Shares
VOYA INVESTMENT MANAGEMENT LLC $62,670 15,906 0.04% Shares
CITADEL ADVISORS LLC $60,282 15,300 0.04% Call option
BLAIR WILLIAM & CO/IL $58,875 14,943 0.04% Shares
JANE STREET GROUP, LLC $57,524 14,600 0.04% Call option
Revolve Wealth Partners, LLC $55,723 14,143 0.04% Shares
Waverly Advisors, LLC $54,577 13,852 0.04% Shares
CAPTRUST FINANCIAL ADVISORS $53,848 13,667 0.04% Shares
NEUBERGER BERMAN GROUP LLC $51,185 12,991 0.04% Shares
Tower Research Capital LLC (TRC) $51,039 12,954 0.03% Shares
SIGNATUREFD, LLC $50,964 12,935 0.03% Shares

Company insiders 27 insiders · 8 officers · 18 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
David-Alexandre C Gros Chief Executive Officer July 31, 2026 F 168,663 0 0 $0
Gregory J. Flesher Chief Executive Officer March 19, 2020 A 171,556 0 0 $0
Paul Sean Little Chief Financial Officer Jan. 10, 2025 A 10,000 0 0 $0
Lee Kalowski Chief Financial Officer April 2, 2015 S 52,346 0 0 $0
Steven Perrin President July 31, 2026 F 81,215 0 0 $0
Bryan E. Smith General Counsel, Corporate Sec Jan. 10, 2025 A — 0 0 $0
Jon Kuwahara Senior Vice President of Finance and Administration Sept. 11, 2020 A 11,250 0 0 $0
Gerald E Quirk General Counsel, Executive VP May 26, 2015 A — 0 0 $0
Allan Kirk Director Jan. 10, 2026 M 3,430 0 0 $0
Jan Hillson Director Jan. 10, 2026 M 3,430 0 0 $0
James A. Robinson Jr. Director Jan. 10, 2026 M 3,430 0 0 $0
June Lee Director Jan. 10, 2026 M 3,430 0 0 $0
John S. Mcbride Director Jan. 10, 2026 M 3,430 0 0 $0
Keith Katkin Director Jan. 10, 2026 M 8,575 0 0 $0
Walter C Ogier Director May 1, 2023 A — 0 0 $0
LYONS GARY A Director May 1, 2023 A — 0 0 $0
CHIMOVITS EREZ Director Jan. 14, 2020 S 3,183,314 0 0 $0
Cheryl Cohen Director July 11, 2019 A — 0 0 $0
Stephen Buckley Jr. Director Jan. 8, 2015 A — 0 0 $0
Apple Tree Partners II - Annex, L.P. Director Sept. 22, 2014 C 3,568,438 0 0 $0
Seth Loring Harrison Director Sept. 22, 2014 C 7,912,079 0 0 $0
APPLE TREE PARTNERS II LP Director Sept. 22, 2014 C 4,218,641 0 0 $0
BARBERICH TIMOTHY J Director Sept. 22, 2014 C 121,077 0 0 $0
Satter Muneer A 10% owner Sept. 22, 2014 C 1,771,688 0 0 $0
Catherine C. Turkel — March 19, 2020 A 98,199 0 0 $0
Jodie Pope Morrison — June 30, 2017 A — 0 0 $0
Christine Ocampo — May 24, 2017 A 21,590 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 5 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
OrbiMed Israel BioFund GP Limited Partnership, OrbiMed Israel GP Ltd. ×9 filings Jan. 5, 2021 — Initial filing — SEC
Novartis Bioventures Ltd., Novartis AG ×3 filings April 5, 2019 — Initial filing — SEC
Apple Tree Partners II, L.P., Apple Tree Ventures II, L.P., Apple Tree Partners II - Annex, L.P., Apple Tree Ventures II - Annex, LLC, Apple Tree Partners IV, L.P., ATP III GP, Ltd., Seth L. Harrison ×4 filings May 15, 2018 — Initial filing — SEC
Novartis Bioventures Ltd. (2), Novartis AG (2) May 16, 2017 — Initial filing — SEC
Otic Pharma, Ltd. Jan. 5, 2017 — Initial filing — SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 17 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWC · iShares Trust 0.06% 263,383 SH Aug. 8, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… 0.02% 17,832 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.02% 83,093 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.02% 705,851 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 442,869 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.01% 1,996,832 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.01% 32,354 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.01% 3,517 NS May 31, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.01% 39,630 NS May 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.00% 165,567 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.00% 2,750 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 2,782 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 70 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 17,419 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 854,634 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,483,162 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 7,403 SH Aug. 8, 2026 Daily