KYTX Kyverna Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$9.13
Price · Aug 19, 2026
Fundamentals as of Aug 11, 2026

KYTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$9.13
Market Cap
$551M
P/E (TTM)
-2.5
EPS (TTM)
$-3.64
Revenue (TTM)
Div Yield
ROE
-77.4%
Debt/Equity
52W Range
$3 – $14

KYTX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS $-3.64
3-point trend, +95.9%
2023-12-31 2025-12-31
Free Cash Flow $-154M
2-point trend, -32.0%
2024-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
KYTX
Peer Median
P/E (TTM)
2-point trend, -129.9%
-2.5
19.6
P/B
2-point trend, +303.1%
2.4
3.1
Price / FCF
2-point trend, -166.1%
-3.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
KYTX
Peer Median
ROA
2-point trend, +19.7%
-53.9%
-56.6%
ROE
2-point trend, -72.9%
-77.4%
-70.8%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
KYTX
Peer Median
Current Ratio
2-point trend, -9.9%
7.8
5.2
Quick Ratio
2-point trend, -9.7%
7.7

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
KYTX
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
KYTX
Peer Median
EPS (Diluted)
3-point trend, +95.9%
$-3.64

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
KYTX
Peer Median

KYTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 12 analysts
  • Strong Buy 4 33.3%
  • Buy 7 58.3%
  • Hold 1 8.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

5 analysts · 2026-08-13
Median target $32.00 +250.5%
Mean target $30.40 +233.0%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.08%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.66 $-0.77 0.11%
Dec. 31, 2025 $-0.80 $-0.88 0.08%
Sept. 30, 2025 $-0.85 $-0.99 0.14%
June 30, 2025 $-0.97 $-1.06 0.09%
March 31, 2025 $-1.03 $-1.14 0.11%
Dec. 31, 2024 $-0.88 $-0.85 -0.03%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
KYTX $568M -2.6 -77.4%
ARTV -1.3 -99.2%
EIKN
OVID $212M -4.0 1181.3% -240.1% -18.7%
PRLD -2.2 73.4% -819.6% -137.7%
VSTM $600M -2.6 209.1% -677.6% -449.2%
ZURA
EVMN $540M -1.5 85.7% -529.8% -401.2%
CCCC $185M -1.5 1.0% -292.1% -48.8%
MPLT $773M -0.9 -151.1%
CABA $220M -1.0 -115.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 13
Annual Income Statement data for KYTX
Metric Trend 202520242023
R&D Expense 3-point trend, +167.9% $134M $112M $50M
SG&A Expense 3-point trend, +189.2% $36M $30M $12M
Operating Expenses 3-point trend, +172.1% $170M $143M $62M
Operating Income 3-point trend, -172.1% $-170M $-143M $-62M
Interest Income 3-point trend, +298.5% $9M $15M $2M
Other Non-op 3-point trend, -54.5% $-85.0K $-90.0K $-55.0K
Income Tax Flat — no change across 3 periods $0 $0 $0
Net Income 3-point trend, -167.2% $-161M $-127M $-60M
EPS (Basic) 3-point trend, +95.9% $-3.64 $-3.33 $-89.61
EPS (Diluted) 3-point trend, +95.9% $-3.64 $-3.33 $-89.61
Shares (Basic) 3-point trend, +6470.5% 44,259,999 38,334,571 673,622
Shares (Diluted) 3-point trend, +6470.5% 44,259,999 38,334,571 673,622
EBITDA 2-point trend, -19.6% $-168M $-140M ·
Balance Sheet 19
Annual Balance Sheet data for KYTX
Metric Trend 202520242023
Cash & Equivalents 3-point trend, +258.2% $124M $97M $35M
Short-term Investments 3-point trend, +577.7% $155M $189M $23M
Prepaid Expense 3-point trend, +18.6% $4M $5M $3M
Current Assets 3-point trend, +366.4% $283M $291M $61M
PP&E (Net) 3-point trend, -33.5% $2M $3M $2M
PP&E (Gross) 3-point trend, +10.0% $5M $7M $5M
Accum. Depreciation 3-point trend, +50.7% $4M $4M $2M
Other Non-current Assets 3-point trend, +46.1% $5M $3M $3M
Total Assets 3-point trend, +290.8% $294M $305M $75M
Accounts Payable 3-point trend, +21.8% $5M $5M $4M
Current Liabilities 3-point trend, +83.7% $36M $34M $20M
Capital Leases 3-point trend, -93.9% $320.0K $4M $5M
Total Liabilities 3-point trend, +136.6% $62M $38M $26M
Common Stock 2-point trend, +1000.00 $1.0K $0 ·
Retained Earnings 3-point trend, -212.3% $-425M $-264M $-136M
AOCI 3-point trend, +2325.0% $97.0K $105.0K $4.0K
Stockholders' Equity 3-point trend, +1867.8% $232M $267M $-13M
Liabilities + Equity 3-point trend, +290.8% $294M $305M $75M
Shares Outstanding 3-point trend, +4730.8% 60,389,893 43,214,918 1,250,103
Cash Flow 12
Annual Cash Flow data for KYTX
Metric Trend 202520242023
D&A 3-point trend, +5.4% $2M $2M $2M
Stock-based Comp 3-point trend, +354.1% $10M $8M $2M
Other Non-cash 2-point trend, -256.5% $-4M $3M ·
Operating Cash Flow 3-point trend, -193.3% $-154M $-114M $-52M
CapEx 3-point trend, -99.2% $5.0K $2M $621.0K
Investing Cash Flow 3-point trend, +555.5% $40M $-161M $-9M
Stock Issued 2-point trend, +16940000.00 $17M $0 ·
Net Stock Activity $17M · ·
Financing Cash Flow 3-point trend, +142.9% $141M $337M $58M
Net Change in Cash 3-point trend, +992.8% $27M $62M $-3M
Taxes Paid Flat — no change across 2 periods $0 $0 ·
Free Cash Flow 2-point trend, -32.0% $-154M $-116M ·
Profitability 2
Annual Profitability data for KYTX
Metric Trend 202520242023
ROA 2-point trend, +19.7% -53.9% -67.1% ·
ROE 2-point trend, -72.9% -77.4% -44.8% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for KYTX
Metric Trend 202520242023
Current Ratio 2-point trend, -9.9% 7.8 8.6 ·
Quick Ratio 2-point trend, -9.7% 7.7 8.5 ·
Per Share 4
Annual Per Share data for KYTX
Metric Trend 202520242023
Book Value / Share 2-point trend, -37.7% $3.85 $6.17 ·
Cash Flow / Share 2-point trend, -16.5% $-3.47 $-2.98 ·
Cash / Share 2-point trend, -8.1% $2.05 $2.24 ·
EPS (TTM) 3-point trend, +95.9% $-3.64 $-3.33 $-89.61
Valuation (TTM) 8
Annual Valuation (TTM) data for KYTX
Metric Trend 202520242023
Net Income TTM 3-point trend, -167.2% $-161M $-127M $-60M
Market Cap 2-point trend, +251.2% $568M $162M ·
P/E 2-point trend, -129.9% -2.6 -1.1 ·
P/B 2-point trend, +303.1% 2.4 0.6 ·
P / Tangible Book 2-point trend, +303.1% 2.4 0.6 ·
P / Cash Flow 2-point trend, -161.0% -3.7 -1.4 ·
P / FCF 2-point trend, -166.1% -3.7 -1.4 ·
Earnings Yield 2-point trend, +56.5% -38.7% -89.0% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-31
Net Income $-161M$-127M$-60M
Diluted EPS $-3.64$-3.33$-89.61
Balance Sheet
2025-12-312024-12-312023-12-31
Current Ratio 7.88.6
Quick Ratio 7.78.5
Cash Flow
2025-12-312024-12-312023-12-31
Free Cash Flow $-154M$-116M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 133 filers · $284.7M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
37 (+14 vs prior Q) 22 (+10 vs prior Q) 31 (-3 vs prior Q) 30 (-3 vs prior Q) +2.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
GordonMD Global Investments LP $37,821,328 4,244,818 13.29% Shares
GILEAD SCIENCES, INC. $36,763,720 4,126,119 12.91% Shares
Vida Ventures Advisors, LLC $27,143,544 4,523,924 9.53% Shares
Bain Capital Life Sciences Investors, LLC $25,705,350 2,885,000 9.03% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $17,820,000 2,000,000 6.26% Shares
VANGUARD CAPITAL MANAGEMENT LLC $16,906,288 1,897,451 5.94% Shares
Insight Holdings Group, LLC $8,812,471 989,054 3.10% Shares
STATE STREET CORP $8,751,696 982,233 3.07% Shares
GEODE CAPITAL MANAGEMENT, LLC $8,083,958 907,053 2.84% Shares
Propel Bio Management, LLC $7,869,294 883,198 2.76% Shares
Woodline Partners LP $7,531,846 845,325 2.65% Shares
AIGH Capital Management LLC $6,449,976 723,903 2.27% Shares
MILLENNIUM MANAGEMENT LLC $5,700,440 639,780 2.00% Shares
MBB PUBLIC MARKETS I LLC $5,474,990 614,477 1.92% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $4,455,000 500,000 1.56% Shares
D. E. Shaw & Co., Inc. $4,036,381 453,017 1.42% Shares
MORGAN STANLEY $3,538,945 397,188 1.24% Shares
RENAISSANCE TECHNOLOGIES LLC $2,975,040 333,899 1.05% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $2,848,224 319,666 1.00% Shares
BNP PARIBAS FINANCIAL MARKETS $2,767,731 310,632 0.97% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $2,514,304 282,189 0.88% Shares
VANGUARD FIDUCIARY TRUST CO $2,313,633 259,667 0.81% Shares
Walleye Capital LLC $2,188,180 245,587 0.77% Shares
Y-Intercept (Hong Kong) Ltd $2,159,668 242,387 0.76% Shares
BANK OF AMERICA CORP /DE/ $2,123,797 238,361 0.75% Shares
Nuveen, LLC $2,082,650 233,743 0.73% Shares
Burkehill Global Management, LP $1,782,000 200,000 0.63% Shares
Simplify Asset Management Inc. $1,626,993 182,603 0.57% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,388,178 155,800 0.49% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $1,335,609 149,900 0.47% Shares
TD Asset Management Inc $1,298,027 145,682 0.46% Shares
GOLDMAN SACHS GROUP INC $1,115,051 125,146 0.39% Shares
Qube Research & Technologies Ltd $1,101,686 123,646 0.39% Shares
CITADEL ADVISORS LLC $1,098,603 123,300 0.39% Call option
BARCLAYS PLC $1,011,437 113,517 0.36% Shares
WESBANCO BANK INC $982,773 110,300 0.35% Shares
Balyasny Asset Management L.P. $855,788 96,048 0.30% Shares
FMR LLC $855,752 96,044 0.30% Shares
Susquehanna Portfolio Strategies, LLC $791,609 88,845 0.28% Shares
Squarepoint Ops LLC $738,345 82,867 0.26% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $732,464 82,207 0.26% Shares
NANO CAP NEW MILLENNIUM GROWTH FUND L P $623,700 70,000 0.22% Shares
AMERICAN CENTURY COMPANIES INC $617,917 69,351 0.22% Shares
Man Group plc $611,582 68,640 0.21% Shares
DIMENSIONAL FUND ADVISORS LP $594,555 66,729 0.21% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $492,723 55,300 0.17% Put option
TWO SIGMA ADVISERS, LP $464,360 49,400 0.16% Shares
TWO SIGMA INVESTMENTS, LP $457,252 51,319 0.16% Shares
CITADEL ADVISORS LLC $454,410 51,000 0.16% Put option
RHUMBLINE ADVISERS $447,168 50,188 0.16% Shares
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC $404,158 45,360 0.14% Shares
ACT CAPITAL MANAGEMENT, LLC $356,400 40,000 0.13% Shares
Kera Capital Partners, Inc. $356,400 40,000 0.13% Shares
CANADA PENSION PLAN INVESTMENT BOARD $356,400 40,000 0.13% Shares
WELLINGTON MANAGEMENT GROUP LLP $340,389 38,203 0.12% Shares
WELLS FARGO & COMPANY/MN $315,548 35,415 0.11% Shares
Bank of New York Mellon Corp $314,523 35,300 0.11% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $314,523 35,300 0.11% Call option
BlackRock, Inc. $267,630 30,037 0.09% Shares
JANE STREET GROUP, LLC $245,025 27,500 0.09% Put option
Mitsubishi UFJ Asset Management Co., Ltd. $229,352 25,741 0.08% Shares
MetLife Investment Management, LLC $228,319 25,625 0.08% Shares
Spark Investment Management LLC $223,641 25,100 0.08% Shares
XTX Topco Ltd $195,111 21,898 0.07% Shares
ALLIANCEBERNSTEIN L.P. $190,723 22,100 0.07% Shares
Quantbot Technologies LP $189,667 21,287 0.07% Shares
Phoenix Wealth Advisors $176,418 19,800 0.06% Shares
JANE STREET GROUP, LLC $176,418 19,800 0.06% Call option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $171,428 19,240 0.06% Shares
CITIGROUP INC $164,265 18,436 0.06% Shares
Vanguard Personalized Indexing Management, LLC $160,264 17,987 0.06% Shares
WINTON GROUP Ltd $155,034 17,400 0.05% Shares
JANE STREET GROUP, LLC $154,268 17,314 0.05% Shares
AlphaQuest LLC $153,624 16,343 0.05% Shares
Invesco Ltd. $149,091 16,733 0.05% Shares
Vanguard Global Advisers, LLC $133,552 14,989 0.05% Shares
Cubist Systematic Strategies, LLC $122,676 20,446 0.04% Shares
IFP Advisors, Inc $111,375 12,500 0.04% Shares
Police & Firemen's Retirement System of New Jersey $110,270 12,376 0.04% Shares
CAXTON CORP $110,009 12,347 0.04% Shares
CITADEL ADVISORS LLC $109,709 12,313 0.04% Shares
FEDERATED HERMES, INC. $106,920 12,000 0.04% Shares
COMMONWEALTH EQUITY SERVICES, LLC $105,580 11,850 0.04% Shares
Ethic Inc. $105,343 11,823 0.04% Shares
Samalin Investment Counsel, LLC $103,310 11,595 0.04% Shares
ExodusPoint Capital Management, LP $102,251 11,476 0.04% Shares
State of Wyoming $96,665 10,849 0.03% Shares
CAPITAL ADVISORS INC/OK $89,100 10,000 0.03% Shares
Grey Ledge Advisors, LLC $89,100 10,000 0.03% Shares
VANGUARD GROUP INC $88,416 9,406 0.03% Shares
China Universal Asset Management Co., Ltd. $86,213 9,676 0.03% Shares
Nuveen Asset Management, LLC $85,452 22,848 0.03% Shares
NEW YORK STATE COMMON RETIREMENT FUND $80,190 9,000 0.03% Shares
LOS ANGELES CAPITAL MANAGEMENT LLC $76,475 8,583 0.03% Shares
Point72 Asia (Singapore) Pte. Ltd. $64,704 10,784 0.02% Shares
NORTHERN TRUST CORP $58,637 6,581 0.02% Shares
Legal & General Group Plc $36,282 4,072 0.01% Shares
OSAIC HOLDINGS, INC. $35,104 3,940 0.01% Shares
DEUTSCHE BANK AG\ $34,900 3,917 0.01% Shares
Ameritas Investment Partners, Inc. $33,929 3,808 0.01% Shares

Company insiders 16 insiders · 9 officers · 9 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Warner Weston Biddle Chief Executive Officer March 13, 2026 A 58,000 0 0 $0
Gregory S. Martini Chief Financial Officer May 18, 2026 A 0 0 $0
Marc Grasso Chief Financial Officer March 13, 2026 A 10,000 0 0 $0
Ryan Alexander Jones Chief Financial Officer April 11, 2024 A 55,950 0 0 $0
Christi Shaw Executive Chairperson May 27, 2026 F 66,741 0 0 $0
Nadia Dac Chief Commercial Officer May 4, 2026 A 0 0 $0
Naji Gehchan Exhibit 24 - Power of Attorney Chief Medical & Development Officer March 13, 2026 A 18,000 0 0 $0
Mayobanex Pujols Chief Technology Officer Feb. 9, 2026 A 0 0 $0
Karen Marie Walker Chief Technology Officer Dec. 15, 2025 M 22,636 0 1 $-292,776
Mert Aktar Director May 27, 2026 A 21,727 0 0 $0
Fred Cohen Director May 27, 2026 A 21,727 0 0 $0
Ian T Clark Director May 27, 2026 A 21,727 0 0 $0
Beth C Seidenberg Director May 27, 2026 A 21,727 1 0 $999,998
Sravan Kumar Emany Director Feb. 24, 2026 A 11,006 0 0 $0
Andrew Craig Miller Director Feb. 24, 2026 A 11,006 0 0 $0
Daniel K Spiegelman Director May 29, 2025 A 16,634 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Vida Ventures, LLC, VV Manager LLC, Vida Ventures GP III, L.L.C., Vida Ventures III, L.P., Vida Ventures III-A, L.P., Fred Cohen May 3, 2024 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 19 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWC · iShares Trust 0.07% 143,082 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.03% 3,277 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.02% 2,112 NS May 31, 2026 N-PORT
IBB · iShares Trust 0.02% 275,107 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.02% 65,620 NS May 31, 2026 N-PORT
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 33,322 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.02% 348,604 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.01% 1,051,890 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 241,414 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.01% 30,633 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.01% 167,964 NS May 31, 2026 N-PORT
IWO · iShares Trust 0.00% 33,331 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 15,873 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 15,000 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 4,410 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 448,147 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 1,403,697 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 3,918 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 3,535 SH Aug. 8, 2026 Daily