Performance vs S&P 500

03
Tracked Q1 2025–Q2 2026 +151.4%
S&P 500 total return (same window) +37.0%
Excess return +114.4%

Annualized: +109.2% · S&P 500: +28.7%

Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.

Priceable coverage: 99.8% · Options excluded: 0.0%

Sector breakdown

04
Healthcare 98.5%
Other/Unmapped 1.5%

Full portfolio 15 positions

05
Type Streak 8Q trend
PTGX Protagonist Therapeutics, Inc. - Common Stock $300,220,852 37.59% 2,449,183 $42,076,964
NBTX Nanobiotix S.A. - ADSs $212,017,863 26.55% 5,623,816 $38,410,663
MGTX MeiraGTx Holdings plc - Ordinary Shares $89,720,775 11.23% 6,641,064 $32,209,161
RAPP Rapport Therapeutics, Inc. - Common Stock $74,360,823 9.31% 1,784,517 $18,523,286
CTNM Contineum Therapeutics, Inc. - Common stock $32,438,645 4.06% 1,979,173 $6,590,646
LEGN Legend Biotech Corporation - American Depositary Shares $23,525,244 2.95% 814,586 $8,789,383
CVRX CVRx, Inc. - Common Stock $20,687,786 2.59% 4,024,861 $-17,387,399
XNCR Xencor, Inc. - Common Stock $12,043,798 1.51% 748,062 $3,022,170
Unknown issuer (CUSIP: 15675D103) $11,842,506 1.48% 53,586 Up ×1
FATE Fate Therapeutics, Inc. - Common Stock $9,123,473 1.14% 3,379,064 $5,068,596
PRCT PROCEPT BioRobotics Corporation - Common Stock $8,082,263 1.01% 357,939 $-869,791
NMRA Neumora Therapeutics, Inc. - Common Stock $3,144,057 0.39% 1,849,445 $-462,361
VOR Vor Biopharma Inc. - Common Stock $989,206 0.12% 53,732 $30,627
LAB Standard BioTools Inc. - Common Stock $256,655 0.03% 311,967 $-30,136
ACET Adicet Bio, Inc. - Common Stock $196,811 0.02% 22,779 $41,686

Biggest new bets

09

New positions opened this quarter, largest first.

SecurityValueShares% of portfolio
Unknown issuer (CUSIP: 15675D103) $11,842,506 53,586 1.48%

Top movers (QoQ)

10
SecurityActionShares ΔValue Δ
PTGX Price move only +0 +$42.1M
NBTX Price move only +0 +$38.4M
MGTX Price move only +0 +$32.2M
RAPP Price move only +0 +$18.5M
CVRX Price move only +0 -$17.4M
LEGN Price move only +0 +$8.8M
CTNM Price move only +0 +$6.6M
FATE Price move only +0 +$5.1M
XNCR Price move only +0 +$3.0M
PRCT Price move only +0 -$870K

Exited positions

11

Includes corporate events (mergers, delistings) — not all exits are sells

Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.

SecurityQuarterShares beforeValue beforePrice since exit
ARWR Dec. 31, 2025 247,598 $8,539,655 -3.3%
VOR (filed as VORXXXX) Dec. 31, 2025 53,732 $2,617,823 42.9%
LYEL March 31, 2026 54,887 $1,689,422 -53.8%
RLYB June 30, 2026 152,901 $1,371,522 6.8%
LYEL (filed as LYELXXXX) Sept. 30, 2025 41,165 $368,015 -43.0%
NNOX June 30, 2026 83,554 $189,668 -45.2%
PHGE Dec. 31, 2025 96,866 $50,855 No longer tracked
SENS Dec. 31, 2025 54,621 $23,804 79.0%