MGTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $10.79
Market Cap (MRQ) $1.02B
P/E (TTM) 15.2
EPS (TTM) $0.71
Revenue (TTM) $398M
ROE (TTM) 72.2%
Debt/Equity -4.3
52W Range $7–$15

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04
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10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$81M
2019-12-31 → 2025-12-31
EPS$-1.42
2020-12-31 → 2025-12-31
Free Cash Flow$-50M
2018-12-31 → 2025-12-31
Net margin19.9%
2019-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend MGTX 5Y avg Peer Median Verdict
P/E (TTM) 15.25Y avg ≈-5.7 ≈-5.7 · ·
P/S (TTM) 2.65Y avg ≈20.4 ≈20.4 8.0 Undervalued
P/B (MRQ) 4.75Y avg ≈-18.5 ≈-18.5 4.2 Overvalued
EV / EBITDA -9.0 · · ·
Price / FCF (TTM) 97.15Y avg ≈-8.4 ≈-8.4 · ·
Price / Cash Flow (TTM) 74.25Y avg ≈-25.5 ≈-25.5 · ·
EV / Revenue 10.3 · · ·
EV / FCF -16.7 · · ·
Price / Tangible Book (MRQ) 4.75Y avg ≈4.7 ≈4.7 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 77.7%
Next Report Nov 11, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 13, 2026 $1.71 $-0.47 465.8%
March 31, 2026 May 14, 2026 $-0.57 $-0.41 -39.2%
Dec. 31, 2025 $0.19 $-0.58 132.3%
Sept. 30, 2025 $-0.62 $-0.50 -24.0%
June 30, 2025 $-0.48 $-0.48 -0.65%
March 31, 2025 $-0.51 $-0.50 -2.7%
Dec. 31, 2024 $-0.50 $-0.57 12.5%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 15
Metric Trend 2025202420232022202120202019
Revenue $81M$33M$14M$16M$38M$16M$13M
R&D Expense $130M$119M$104M$86M$67M$34M$25M
SG&A Expense $53M$54M$47M$47M$44M$44M$47M
Operating Expenses $187M$197M$151M$132M$110M$78M$72M
Operating Income $-106M$-164M$-137M$-116M$-73M$-63M$-58M
Interest Expense $12M$13M$13M$5M$288.0K$139.0K$48.6K
Interest Income $2M$4M$2M$777.0K$212.0K$1M$370.6K
Pretax Income $-114M$-148M$-84M$-130M$-80M$-58M$-55M
Income Tax $0$0$0$0$0$0$0
Net Income $-114M$-148M$-84M$-130M$-80M$-58M$-55M
EPS (Basic) $-1.42$-2.12$-1.49$-2.87$-1.80$-1.54·
EPS (Diluted) $-1.42$-2.12$-1.49$-2.87$-1.80$-1.54·
Shares (Basic) 80,430,18669,822,35356,486,52545,177,85744,139,65537,724,189·
Shares (Diluted) 80,430,18669,822,35356,486,52545,177,85744,139,65537,724,189·
EBITDA $-93M$-151M$-123M$-108M$-65M$-58M$-58M
Balance Sheet 27
Metric Trend 2025202420232022202120202019
Cash & Equivalents $66M$104M$130M$116M$138M$210M$227M
Receivables $3M$707.0K$10M$21M···
Inventory ·$385.0K·····
Prepaid Expense $6M$7M$6M$8M$8M$7M$4M
Other Current Assets $2M$2M$1M$2M$2M$5M$2M
Current Assets $92M$124M$160M$154M$183M$273M$269M
PP&E (Net) $105M$103M$116M$109M$76M$44M$24M
PP&E (Gross) $158M$145M$149M$130M$90M$52M$28M
Accum. Depreciation $53M$42M$33M$20M$14M$8M$5M
Intangibles $578.0K$821.0K$1M$1M$2M$2M·
Other Non-current Assets $1M$1M$2M$1M$1M$1M$195.1K
Total Assets $244M$270M$327M$318M$320M$364M$324M
Accounts Payable $10M$24M$16M$17M$15M$7M$4M
Accrued Liabilities $33M$27M$43M$40M$28M$21M$18M
Short-term Debt $25M······
Current Liabilities $123M$61M$67M$82M$68M$54M$49M
Capital Leases $11M$8M$13M$17M$20M$20M$22M
Deferred Tax ···$186.0K$196.0K$214.0K$195.1K
Total Liabilities $250M$202M$189M$200M$135M$125M$133M
Total Debt $25M······
Common Stock $3.0K$3.0K$2.0K$2.0K$2.0K$2.0K$1.4K
Paid-in Capital $808M$774M$694M$582M$529M$504M$396M
Retained Earnings $-816M$-702M$-554M$-470M$-341M$-261M$-203M
AOCI $2M$-4M$-1M$6M$-3M$-5M$-2M
Stockholders' Equity $-6M$68M$138M$118M$185M$239M$191M
Liabilities + Equity $244M$270M$327M$318M$320M$364M$324M
Shares Outstanding 81,120,93178,397,38063,601,01548,477,20944,548,92544,189,15036,791,906
Cash Flow 14
Metric Trend 2025202420232022202120202019
D&A $13M$13M$14M$9M$8M$4M$2M
Stock-based Comp $22M$25M$28M$29M$21M$18M$16M
Deferred Tax $-21M$-24M$-10M$-26M$-37M$-16M$-10M
Amort. of Intangibles ···$200.0K$300.0K$20.0K$0
Other Non-cash $54M$29M$-53M$45M$77M$-13M·
Operating Cash Flow $-46M$-104M$-105M$-73M$-11M$-64M$20M
CapEx $4M$5M$20M$45M$46M$21M$9M
Investing Cash Flow $-4M$23M$34M$-45M$-62M$-37M$-9M
Stock Issued $15M$59M$92M$25M·$87M$155M
Net Stock Activity $15M$59M$92M··$87M$155M
Financing Cash Flow $12M$55M$84M$95M$2M$83M$148M
Taxes Paid $0$0·····
Free Cash Flow $-50M$-109M$-126M$-118M$-57M$-85M$11M
Levered FCF $-62M$-123M·$-123M$-57M$-85M·
Profitability 7
Metric Trend 2025202420232022202120202019
Operating Margin -130.2%-493.4%·-730.9%-194.1%-401.9%-438.4%
Net Margin -140.3%-444.1%·-814.2%-211.0%-372.6%-411.9%
Pretax Margin -140.3%-444.1%·-814.2%-211.0%-372.6%-411.9%
EBITDA Margin -114.8%-454.9%·-676.1%-173.3%-375.1%-438.4%
ROA -44.4%-49.5%-26.1%-40.6%-23.3%-16.9%-26.0%
ROE 8062.2%-180.7%-73.0%-107.8%-42.6%-27.8%-28.4%
ROIC -562.0%-242.1%·-98.8%-39.5%-26.2%·
Liquidity & Solvency 4
Metric Trend 2025202420232022202120202019
Current Ratio 0.72.02.41.92.75.05.5
Quick Ratio 0.61.72.11.42.03.94.6
Debt / Equity -4.3······
Interest Coverage -8.7-12.4-10.3-23.5-254.1-449.4-1198.6
Efficiency 2
Metric Trend 2025202420232022202120202019
Asset Turnover 0.30.1·0.00.10.00.1
Receivables Turnover 43.96.1·····
Per Share 5
Metric Trend 2025202420232022202120202019
Book Value / Share $-0.07$0.87$2.17$2.43$4.16$5.40$5.19
Revenue / Share $1.01$0.48·$0.35$0.85··
Cash Flow / Share $-0.58$-1.50$-1.87$-1.62$-0.24··
Cash / Share $0.81$1.32$2.04$2.38$3.09$4.74$6.18
EPS (TTM) $-1.42$-2.12$-1.49$-2.87$-1.80$-1.54·
Growth Rates 3
Metric Trend 2025202420232022202120202019
Revenue YoY 144.6%137.4%-11.9%-57.8%142.2%··
Revenue CAGR 3Y 72.3%-4.1%-3.4%····
Revenue CAGR 5Y 39.2%······
Valuation (TTM) 14
Metric Trend 2025202420232022202120202019
Revenue TTM $81M$33M$14M$16M$38M$16M$13M
Net Income TTM $-114M$-148M$-84M$-130M$-80M$-58M$-55M
Market Cap $645M$477M$446M$316M$1.06B$669M$737M
Enterprise Value $604M······
P/E -5.6-2.9-4.7-2.3-13.2-9.8·
P/S 7.914.331.919.928.143.055.4
P/B -111.37.03.22.75.72.83.9
P / Tangible Book ·7.13.32.75.82.8·
P / Cash Flow -13.9-4.6-4.2-4.3-100.4-10.536.7
P / FCF -12.9-4.4-3.6-2.7-18.6-7.966.6
EV / EBITDA -6.5······
EV / FCF -12.0······
EV / Revenue 7.4······
Earnings Yield -17.9%-34.8%-21.2%-44.0%-7.6%-10.2%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $81M $33M $14M $16M $38M
Operating Margin % -130.2% -493.4% · -730.9% -194.1%
Net Income $-114M $-148M $-84M $-130M $-80M
Diluted EPS $-1.42 $-2.12 $-1.49 $-2.87 $-1.80

Institutional owners (13F) 164 filers · $1.1B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 164
Value held $1.1B
New positions 41
Exited positions 12
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
41 (+19 vs prior Q) 12 (-4 vs prior Q) 79 (+32 vs prior Q) 22 (-18 vs prior Q) +11.4M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Sanofi $164,791,427 12,197,737 15.52% Shares
PERCEPTIVE ADVISORS LLC $145,727,749 10,786,658 13.72% Shares
Rubric Capital Management LP $122,941,000 9,100,000 11.58% Shares
JOHNSON & JOHNSON $89,720,775 6,641,064 8.45% Shares
BlackRock, Inc. $64,269,475 4,757,178 6.05% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $59,444,000 4,400,000 5.60% Shares
Opaleye Management Inc. $47,960,500 3,550,000 4.52% Shares
MILLENNIUM MANAGEMENT LLC $40,148,370 2,971,752 3.78% Shares
683 Capital Management, LLC $31,073,000 2,300,000 2.93% Shares
Woodline Partners LP $20,266,824 1,500,135 1.91% Shares
STATE STREET CORP $18,822,429 1,393,222 1.77% Shares
MORGAN STANLEY $17,734,617 1,312,703 1.67% Shares
Knoll Capital Management, LLC $16,887,500 1,250,000 1.59% Shares
KENNEDY CAPITAL MANAGEMENT LLC $14,934,238 1,105,421 1.41% Shares
Long Focus Capital Management, LLC $14,594,853 1,080,300 1.37% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $13,714,082 1,015,106 1.29% Shares
D. E. Shaw & Co., Inc. $11,522,706 852,902 1.08% Shares
HEIGHTS CAPITAL MANAGEMENT, INC $11,483,500 850,000 1.08% Shares
GEODE CAPITAL MANAGEMENT, LLC $11,471,097 849,082 1.08% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $9,775,336 723,563 0.92% Shares
CITADEL ADVISORS LLC $8,788,106 650,489 0.83% Shares
Erste Asset Management GmbH $8,667,648 691,200 0.82% Shares
Nuveen, LLC $8,639,091 639,459 0.81% Shares
J. Goldman & Co LP $8,132,642 601,972 0.77% Shares
PFM Health Sciences, LP $6,150,914 455,286 0.58% Shares
NORTHERN TRUST CORP $5,537,141 409,855 0.52% Shares
PANAGORA ASSET MANAGEMENT INC $4,730,851 350,174 0.45% Shares
GOLDMAN SACHS GROUP INC $4,423,390 327,416 0.42% Shares
VANGUARD GROUP INC $3,933,287 494,753 0.37% Shares
BANK OF AMERICA CORP /DE/ $3,914,117 289,720 0.37% Shares
Point72 Asset Management, L.P. $2,734,329 202,393 0.26% Shares
Ghisallo Capital Management LLC $2,702,000 200,000 0.25% Shares
AQR CAPITAL MANAGEMENT LLC $2,655,837 196,583 0.25% Shares
Privium Fund Management B.V. $2,649,473 196,112 0.25% Shares
JPMORGAN CHASE & CO $2,573,360 205,212 0.24% Shares
UBS Group AG $2,493,594 184,574 0.23% Shares
Squarepoint Ops LLC $2,194,186 162,412 0.21% Shares
Y-Intercept (Hong Kong) Ltd $2,000,358 148,065 0.19% Shares
Russell Investments Group, Ltd. $1,990,413 147,329 0.19% Shares
WELLINGTON MANAGEMENT GROUP LLP $1,930,890 142,923 0.18% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1,924,283 142,434 0.18% Shares
Bank of New York Mellon Corp $1,869,129 138,352 0.18% Shares
BLAIR WILLIAM & CO/IL $1,695,208 125,478 0.16% Shares
Voleon Capital Management LP $1,591,343 117,790 0.15% Shares
Swiss National Bank $1,505,014 111,400 0.14% Shares
BARCLAYS PLC $1,336,882 98,955 0.13% Shares
Invesco Ltd. $1,277,235 94,540 0.12% Shares
ALPS ADVISORS INC $1,258,943 93,186 0.12% Shares
Prosight Management, LP $1,215,900 90,000 0.11% Shares
Aquatic Capital Management LLC $1,176,235 87,064 0.11% Shares

Show all 164 institutional owners →

Activists & 5%+ owners 1 position

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Perceptive Advisors LLC, Joseph Edelman, Perceptive Life Sciences Master Fund, Ltd. ×9 filings April 24, 2026 12.60% Amendment · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 19 insiders · 8 officers · 11 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Alexandria Forbes PRESIDENT & CEO Aug. 18, 2026 S 1,325,695 0 4 $-2,285,805
Richard Giroux CFO & COO July 21, 2026 S 908,530 0 3 $-1,485,760
Katherine Breedis Chief Financial Officer Dec. 29, 2018 A · 0 0 $0
Stuart Naylor CHIEF SCI OFCR, OPHTHALMOLOGY July 7, 2026 S 640,846 0 3 $-668,377
Robert J Wollin GENERAL COUNSEL AND SECRETARY June 25, 2026 A 57,377 0 0 $0
Robert K Zeldin CHIEF MEDICAL OFFICER June 25, 2026 A 146,204 0 0 $0
Penny Renee Fleck CHIEF DEVELOPMENT OFFICER May 13, 2026 A · 0 0 $0
Bruce Gottlieb General Counsel April 1, 2019 A · 0 0 $0
Alan Sebulsky Director Sept. 23, 2026 A · 0 0 $0
Debra Yu Director June 11, 2026 A · 0 0 $0
Ellen Hukkelhoven Director June 11, 2026 A · 0 0 $0
Keith R. Harris Director June 11, 2026 A 200,000 0 0 $0
Neil Mendoza Director June 11, 2026 A · 0 0 $0
Nicole Seligman Director June 11, 2026 A 5,000 0 0 $0
Thomas E Shenk Director June 11, 2026 A 157,476 0 0 $0
Martin Indyk Director June 6, 2024 A 35,000 0 0 $0
Joel S Marcus Director June 7, 2022 A 12,882 0 0 $0
Arnold J Levine Director June 7, 2022 A · 0 0 $0
Johnson & Johnson Innovation - JJDC, Inc. 10% owner Sept. 15, 2023 J 0 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 19 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
DWAS · Invesco Exchange-Traded Fund Trust … 0.31% 116,546 SH Oct. 2, 2026 Daily
IWC · iShares Trust 0.18% 204,089 SH Sept. 11, 2026 Daily
ESSC · Strategy Shares 0.12% 3,786 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.07% 6,788 SH Oct. 2, 2026 Daily
IBB · iShares Trust 0.07% 535,017 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.04% 447,107 SH Sept. 11, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.04% 51,041 SH Aug. 19, 2026 Daily
IWM · iShares Trust 0.03% 1,527,344 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.02% 28,718 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 55,943 SH Oct. 2, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 345,700 SH Aug. 19, 2026 Daily
ISCG · iShares Trust 0.02% 12,900 SH Sept. 11, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.01% 11,041 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 167,269 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.01% 3,440 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 17,625 SH Sept. 11, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 5,601 SH Aug. 19, 2026 Daily
IWN · iShares Trust · 113,658 SH Sept. 11, 2026 Daily
ISCB · iShares Trust · 1,898 SH Sept. 11, 2026 Daily

MGTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 13 analysts BUY
Median target $23.50 +117.8%
4 30.8% Strong Buy
8 61.5% Buy
1 7.7% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

8 analysts · 2026-10-03

Mean target $27.75 +157.2%

← Below all targets Current price $10.79
Low$16.00 Mean$27.75 High$50.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
MGTX $645M -5.6 144.6% -140.3% 8062.2% ·
MNKD $1.75B 283.5 22.2% 1.7% -11.1% ·
BCAX $953M -6.7 · · -33.0% ·
TRAX · · · · · ·
VOR $506M -0.2 · · 83.4% ·
JANX $833M -7.5 -5.5% -1136.2% -11.7% ·
AKTS · · · · · ·
ODTX · · · · · ·
SVRA $1.23B -11.4 · · -73.4% ·
KURA $913M -3.3 25.2% -413.0% -116.2% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 13, 2026