XNCR Xencor, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$26.50
Price · Aug 19, 2026
Fundamentals as of Aug 5, 2026

XNCR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$26.50
Market Cap
$1.90B
P/E (TTM)
-21.4
EPS (TTM)
$-1.24
Revenue (TTM)
$126M
Div Yield
ROE
-14.0%
Debt/Equity
0.1
52W Range
$7 – $27

XNCR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $126M
10-point trend, +15.2%
2016-12-31 2025-12-31
EPS $-1.24
10-point trend, -215.9%
2016-12-31 2025-12-31
Free Cash Flow $-138M
10-point trend, -248.5%
2016-12-31 2025-12-31
Margins -73.2%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
XNCR
Peer Median
P/E (TTM)
5-point trend, -142.2%
-21.4
P/S (TTM)
5-point trend, -57.4%
15.2
22.4
P/B
5-point trend, -60.7%
3.0
2.7
EV / EBITDA
2-point trend, +33.8%
-11.5
Price / FCF
5-point trend, +95.1%
-13.8

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
XNCR
Peer Median
Operating Margin
5-point trend, -988.4%
-141.3%
Net Profit Margin
5-point trend, -343.7%
-73.2%
-638.9%
ROA
5-point trend, +0.4%
-10.1%
-43.1%
ROE
5-point trend, -15.2%
-14.0%
-49.0%
ROIC
5-point trend, -90.9%
-25.6%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
XNCR
Peer Median
Debt / Equity
2-point trend, -29.2%
0.1
0.0
Current Ratio
5-point trend, +18.7%
6.3
9.0
Quick Ratio
5-point trend, -39.9%
0.9

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
XNCR
Peer Median
Revenue YoY
5-point trend, -54.4%
13.7%
Revenue CAGR 3Y
5-point trend, -54.4%
-8.6%
Revenue CAGR 5Y
5-point trend, -54.4%
0.47%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
XNCR
Peer Median
EPS (Diluted)
5-point trend, -190.5%
$-1.24

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
XNCR
Peer Median

XNCR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 20 analysts
  • Strong Buy 6 30.0%
  • Buy 11 55.0%
  • Hold 3 15.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

12 analysts · 2026-08-17
Median target $28.50 +7.5%
Mean target $29.00 +9.4%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.18%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.29 $-0.85 0.56%
March 31, 2026 $-1.71 $-0.79 -0.92%
Dec. 31, 2025 $-0.09 $-0.62 0.53%
Sept. 30, 2025 $-0.08 $-0.70 0.62%
June 30, 2025 $-0.41 $-0.73 0.32%
March 31, 2025 $-0.66 $-0.61 -0.05%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
XNCR $1.10B -12.3 13.7% -73.2% -14.0%
RXRX $2.16B -2.8 26.9% -863.4% -62.9%
FBRX $353M -5.8 106.6% -2555.2% -86.9%
ZYME $1.97B -24.4 38.9% -76.6% -26.9%
BCAX $953M -6.7 -33.0%
TYRA $1.41B -13.1 -42.7%
JBIO $761M -4.8 -47.7%
TRAX
VIR $841M -1.9 -7.6% -638.9% -51.1%
ABSI $529M -4.2 -38.2% -4113.7% -63.5%
AVBP $854M -4.7 -59.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Revenue 10-point trend, +15.2% $126M $110M $175M $165M $275M $123M $157M $41M $46M $109M
R&D Expense 10-point trend, +361.6% $239M $228M $254M $200M $193M $170M $119M $98M $72M $52M
SG&A Expense 10-point trend, +385.5% $64M $61M $53M $47M $39M $30M $24M $22M $18M $13M
Operating Expenses 10-point trend, +366.4% $303M $289M $307M $247M $231M $199M $143M $120M $89M $65M
Operating Income 10-point trend, -503.0% $-178M $-178M $-132M $-82M $44M $-77M $14M $-79M $-43M $44M
Interest Expense 6-point trend, +29314.3% · · $6M $13.0K $13.0K · · $16.0K $13.0K $21.0K
Interest Income 5-point trend, +3093.0% $28M $32M $19M $5M $862.0K · · · · ·
Other Non-op 10-point trend, -1316.7% $-73.0K $50.0K $-31.0K $-148.0K $-1M $95.0K $-256.0K $-125.0K $-7.0K $6.0K
Pretax Income 10-point trend, -294.4% $-90M $-235M $-120M $-55M $83M $-69M $27M $-70M $-39M $46M
Income Tax 10-point trend, +152.7% $3M $2M $14M $673.0K $0 $0 $312.0K $0 $-463.0K $991.0K
Net Income 10-point trend, -303.7% $-92M $-233M $-133M $-55M $83M $-69M $27M $-70M $-38M $45M
EPS (Basic) 10-point trend, -213.8% $-1.24 $-3.58 $-2.20 $-0.93 $1.42 $-1.21 $0.48 $-1.31 $-0.82 $1.09
EPS (Diluted) 10-point trend, -215.9% $-1.24 $-3.58 $-2.20 $-0.93 $1.37 $-1.21 $0.46 $-1.31 $-0.82 $1.07
Shares (Basic) 10-point trend, +79.9% 74,239,000 65,041,000 60,503,000 59,652,461 58,379,641 57,212,737 56,531,439 53,942,116 46,817,756 41,267,329
Shares (Diluted) 10-point trend, +75.1% 74,239,000 65,041,000 60,503,000 59,652,461 60,495,455 57,212,737 58,467,880 53,942,116 46,817,756 42,388,867
EBITDA 10-point trend, -795.6% $-167M $-166M $-121M $-74M $51M $-71M $18M $-76M $-52M $24M
Balance Sheet 26
Annual Balance Sheet data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Cash & Equivalents 10-point trend, +272.2% $54M $41M $54M $54M $143M $164M $50M $26M $17M $15M
Short-term Investments 4-point trend, +314.7% · · · · · · $479M $268M $208M $116M
Receivables 10-point trend, +240.1% $29M $61M $24M $29M $66M $11M $22M $10M $1M $9M
Prepaid Expense 10-point trend, +685.6% $23M $19M $18M $23M $24M $11M $7M $10M $6M $3M
Current Assets 10-point trend, +323.4% $600M $578M $636M $675M $424M $638M $558M $316M $231M $142M
PP&E (Net) 10-point trend, +1616.8% $53M $60M $66M $59M $28M $22M $16M $12M $7M $3M
PP&E (Gross) 10-point trend, +883.8% $105M $102M $102M $87M $51M $39M $28M $21M $15M $11M
Accum. Depreciation 10-point trend, +582.2% $51M $42M $36M $28M $23M $17M $13M $9M $8M $8M
Intangibles 10-point trend, -19.1% $8M $18M $19M $18M $16M $16M $14M $12M $11M $10M
Other Non-current Assets 10-point trend, +383.5% $498.0K $498.0K $648.0K $613.0K $653.0K $212.0K $311.0K $311.0K $265.0K $103.0K
Total Assets 10-point trend, +104.3% $875M $952M $965M $846M $838M $703M $670M $577M $390M $429M
Accounts Payable 10-point trend, +179.1% $11M $17M $14M $10M $14M $9M $10M $4M $7M $4M
Accrued Liabilities 10-point trend, +422.4% $35M $19M $24M $19M $19M $18M $9M $10M $5M $7M
Current Liabilities 10-point trend, -9.8% $96M $87M $74M $64M $71M $121M $67M $54M $73M $106M
Capital Leases 7-point trend, +655.8% $65M $65M $59M $55M $34M $10M $9M · · ·
Deferred Tax · · · · · · · · · $65.0K
Other Non-current Liabilities $0 · · · · · · · · ·
Total Liabilities 10-point trend, +109.3% $240M $278M $303M $119M $105M $131M $77M $55M $74M $115M
Total Debt 2-point trend, -33.6% $76M $115M · · · · · · · ·
Common Stock 10-point trend, +54.1% $718.0K $703.0K $611.0K $601.0K $595.0K $580.0K $569.0K $563.0K $470.0K $466.0K
Paid-in Capital 10-point trend, +158.5% $1.43B $1.38B $1.13B $1.07B $1.02B $938M $888M $845M $571M $553M
Retained Earnings 10-point trend, -234.5% $-796M $-704M $-471M $-338M $-283M $-366M $-296M $-323M $-253M $-238M
AOCI 10-point trend, +209.4% $2M $-663.0K $1M $-7M $-2M $74.0K $1M $-971.0K $-2M $-1M
Stockholders' Equity 10-point trend, +88.1% $636M $678M $662M $727M $734M $572M $593M $522M $316M $338M
Liabilities + Equity 10-point trend, +104.3% $875M $952M $965M $846M $838M $703M $670M $577M $390M $429M
Shares Outstanding 10-point trend, +54.3% 71,872,000 70,256,000 60,998,191 59,997,713 59,355,558 57,873,444 56,902,301 56,279,542 47,002,488 46,567,978
Cash Flow 15
Annual Cash Flow data for XNCR
Metric Trend 2025202420232022202120202019201820172016
D&A 10-point trend, +617.1% $11M $12M $11M $9M $7M $6M $4M $3M $2M $1M
Stock-based Comp 10-point trend, +450.8% $43M $53M $54M $49M $37M $32M $32M $21M $14M $8M
Deferred Tax Flat — no change across 5 periods $0 $0 $0 $0 $0 · · · · ·
Amort. of Intangibles 10-point trend, +12.5% $900.0K $1M $1M $1M $1M $1M $900.0K $900.0K $800.0K $800.0K
Other Non-cash 10-point trend, -257.2% $-97M $-35M $-10M $22M $-144M $27M $1M $-33M $-439.0K $62M
Operating Cash Flow 10-point trend, -241.9% $-135M $-202M $-78M $24M $-17M $-5M $64M $-80M $-34M $95M
CapEx 10-point trend, +109.0% $3M $6M $18M $38M $13M $11M $7M $7M $5M $2M
Investing Cash Flow 10-point trend, +165.3% $140M $-8M $-111M $-120M $-46M $100M $-51M $-165M $32M $-214M
Stock Issued 8-point trend, -100.0% $0 $201M $0 $0 $29M $0 · $260M · $127M
Net Stock Activity 7-point trend, -100.0% $0 $201M $0 $0 $29M · · $260M · $127M
Financing Cash Flow 10-point trend, -93.2% $8M $197M $189M $6M $43M $18M $11M $254M $4M $121M
Net Change in Cash 10-point trend, +576.0% $13M $-13M $228.0K $-90M $-20M $113M $24M $10M $2M $2M
Taxes Paid 10-point trend, +681.2% $7M $6M $0 $700.0K $0 $0 $400.0K $233.0K $969.0K $936.0K
Free Cash Flow 10-point trend, -248.5% $-138M $-208M $-96M $-14M $-30M $-16M $57M $-87M $-39M $93M
Levered FCF 3-point trend, -210.9% · · $-103M · · · · · $-39M $93M
Profitability 7
Annual Profitability data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Operating Margin 8-point trend, +27.7% -141.3% -161.5% -75.8% -50.1% 15.9% -62.6% 8.8% -195.5% · ·
Net Margin 8-point trend, +57.8% -73.2% -210.5% -76.2% -33.5% 30.0% -56.5% 17.2% -173.4% · ·
Pretax Margin 8-point trend, +58.8% -71.4% -212.6% -68.5% -33.1% 30.0% -56.5% 17.3% -173.4% · ·
EBITDA Margin 8-point trend, +29.1% -133.0% -150.5% -69.2% -44.8% 18.6% -57.9% 11.6% -187.5% · ·
ROA 9-point trend, -235.2% -10.1% -24.3% · -6.6% 10.7% -10.1% 4.3% -14.6% -11.9% 7.4%
ROE 9-point trend, -241.1% -14.0% -34.7% · -7.6% 12.2% -12.2% 4.5% -13.4% -15.8% 9.9%
ROIC 8-point trend, -471.8% -25.6% -22.7% · -11.5% 6.0% -13.4% 2.3% · -18.8% 6.9%
Liquidity & Solvency 5
Annual Liquidity & Solvency data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Current Ratio 9-point trend, +369.3% 6.3 6.6 · 10.6 6.0 5.3 8.4 5.9 2.3 1.3
Quick Ratio 9-point trend, -33.4% 0.9 1.2 · 1.3 3.0 1.4 8.3 5.7 2.2 1.3
Debt / Equity 2-point trend, -29.2% 0.1 0.2 · · · · · · · ·
LT Debt / Equity 2-point trend, -29.2% 0.1 0.2 · · · · · · · ·
Interest Coverage 4-point trend, -102.0% · · -21.4 · · · · -4960.6 -4120.2 1073.3
Efficiency 2
Annual Efficiency data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Asset Turnover 7-point trend, +63.6% 0.1 0.1 · 0.2 0.4 0.2 0.3 0.1 · ·
Receivables Turnover 7-point trend, -61.1% 2.8 2.6 · 3.5 7.1 7.4 9.9 7.2 · ·
Per Share 5
Annual Per Share data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Book Value / Share 9-point trend, +31.2% $8.84 $9.64 · $12.13 $12.36 $9.89 $10.42 $9.27 $6.00 $6.74
Revenue / Share 8-point trend, +124.7% $1.69 $1.70 $2.89 $2.76 $4.55 $2.14 $2.68 $0.75 · ·
Cash Flow / Share 10-point trend, -181.5% $-1.82 $-3.11 $-1.29 $0.41 $-0.28 $-0.09 $1.10 $-1.48 $-0.72 $2.23
Cash / Share 9-point trend, +141.2% $0.75 $0.58 · $0.90 $2.42 $2.83 $0.88 $0.47 $0.35 $0.31
EPS (TTM) 10-point trend, -215.9% $-1.24 $-3.58 $-2.20 $-0.93 $1.37 $-1.21 $0.46 $-1.31 $-0.82 $1.07
Growth Rates 3
Annual Growth Rates data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Revenue YoY 5-point trend, -89.0% 13.7% -36.7% 6.1% -40.2% 124.2% · · · · ·
Revenue CAGR 3Y 3-point trend, -169.1% -8.6% -26.2% 12.5% · · · · · · ·
Revenue CAGR 5Y 0.47% · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for XNCR
Metric Trend 2025202420232022202120202019201820172016
Revenue TTM 10-point trend, +15.2% $126M $110M $175M $165M $275M $123M $157M $41M $46M $109M
Net Income TTM 10-point trend, -303.7% $-92M $-233M $-133M $-55M $83M $-69M $27M $-70M $-38M $45M
Market Cap 9-point trend, -10.2% $1.10B $1.61B · $1.56B $2.38B $2.53B $1.96B $2.04B $1.03B $1.23B
Enterprise Value 2-point trend, -33.5% $1.12B $1.69B · · · · · · · ·
P/E 10-point trend, -150.2% -12.3 -6.4 -9.7 -28.0 29.3 -36.1 74.8 -27.6 -26.7 24.6
P/S 9-point trend, -22.1% 8.8 14.6 · 9.5 8.7 20.6 12.5 50.1 22.3 11.2
P/B 9-point trend, -55.7% 1.7 2.4 · 2.1 3.2 4.4 3.3 3.9 3.7 3.9
P / Tangible Book 6-point trend, -61.3% 1.8 2.4 2.0 2.2 3.3 4.5 · · · ·
P / Cash Flow 9-point trend, -162.9% -8.1 -8.0 · 63.8 -141.3 -504.6 30.4 -25.5 -30.6 13.0
P / FCF 9-point trend, -160.5% -8.0 -7.8 · -111.5 -79.0 -162.5 34.3 -23.4 -26.4 13.2
EV / EBITDA 2-point trend, +33.8% -6.7 -10.2 · · · · · · · ·
EV / FCF 2-point trend, -0.2% -8.1 -8.1 · · · · · · · ·
EV / Revenue 2-point trend, -41.5% 8.9 15.3 · · · · · · · ·
Earnings Yield 10-point trend, -299.0% -8.1% -15.6% -10.4% -3.6% 3.4% -2.8% 1.3% -3.6% -3.7% 4.1%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $126M$110M$175M$165M$275M
Operating Margin % -141.3%-161.5%-75.8%-50.1%15.9%
Net Income $-92M$-233M$-133M$-55M$83M
Diluted EPS $-1.24$-3.58$-2.20$-0.93$1.37
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.10.2
Current Ratio 6.36.610.66.0
Quick Ratio 0.91.21.33.0
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-138M$-208M$-96M$-14M$-30M

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Institutional owners (13F) 222 filers · $984.4M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
39 (+17 vs prior Q) 21 (-4 vs prior Q) 74 (+7 vs prior Q) 54 (-4 vs prior Q) +6.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
PRIMECAP MANAGEMENT CO/CA/ $163,919,285 10,181,322 16.65% Shares
BVF INC/IL $114,852,892 7,133,720 11.67% Shares
RTW INVESTMENTS, LP $109,117,122 6,777,461 11.08% Shares
RA CAPITAL MANAGEMENT, L.P. $84,915,811 5,274,274 8.63% Shares
STATE STREET CORP $79,759,658 4,954,016 8.10% Shares
VANGUARD CAPITAL MANAGEMENT LLC $52,788,712 3,278,802 5.36% Shares
TCG Crossover Management, LLC $39,479,422 2,452,138 4.01% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $35,672,609 2,215,690 3.62% Shares
GEODE CAPITAL MANAGEMENT, LLC $26,483,390 1,644,479 2.69% Shares
BAKER BROS. ADVISORS LP $17,743,907 1,102,106 1.80% Shares
DIMENSIONAL FUND ADVISORS LP $14,763,797 917,006 1.50% Shares
MILLENNIUM MANAGEMENT LLC $13,744,200 853,677 1.40% Shares
TWO SIGMA INVESTMENTS, LP $13,194,192 819,515 1.34% Shares
GOLDMAN SACHS GROUP INC $13,186,109 819,013 1.34% Shares
JOHNSON & JOHNSON $12,043,798 748,062 1.22% Shares
Jefferies Financial Group Inc. $11,599,084 720,440 1.18% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $11,386,596 707,242 1.16% Shares
PANAGORA ASSET MANAGEMENT INC $10,950,930 680,182 1.11% Shares
Deep Track Capital, LP $9,556,171 593,551 0.97% Shares
TORONTO DOMINION BANK $7,905,100 491,000 0.80% Shares
VANGUARD FIDUCIARY TRUST CO $7,842,052 487,084 0.80% Shares
Seven Fleet Capital Management LP $7,828,524 368,305 0.80% Shares
TWO SIGMA ADVISERS, LP $7,756,046 506,600 0.79% Shares
BlackRock, Inc. $6,090,598 378,298 0.62% Shares
BANK OF AMERICA CORP /DE/ $4,526,821 281,169 0.46% Shares
Velan Capital Investment Management LP $4,105,500 255,000 0.42% Shares
Public Sector Pension Investment Board $4,101,330 254,741 0.42% Shares
ADAR1 Capital Management, LLC $3,744,216 232,560 0.38% Shares
Hudson Bay Capital Management LP $3,381,000 210,000 0.34% Shares
Bank of New York Mellon Corp $3,228,292 200,515 0.33% Shares
BARCLAYS PLC $3,221,046 200,065 0.33% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $3,220,000 200,000 0.33% Shares
CITADEL ADVISORS LLC $3,072,299 190,826 0.31% Shares
RHUMBLINE ADVISERS $2,924,017 181,617 0.30% Shares
AMERICAN CENTURY COMPANIES INC $2,901,300 180,205 0.29% Shares
CITIGROUP INC $2,627,037 163,170 0.27% Shares
Susquehanna Portfolio Strategies, LLC $2,569,302 159,584 0.26% Shares
KORNITZER CAPITAL MANAGEMENT INC /KS $2,437,701 151,410 0.25% Shares
Trexquant Investment LP $2,327,336 144,555 0.24% Shares
Jump Financial, LLC $2,109,100 131,000 0.21% Shares
HSBC HOLDINGS PLC $2,083,001 125,482 0.21% Shares
AMERIPRISE FINANCIAL INC $2,002,324 124,368 0.20% Shares
DEUTSCHE BANK AG\ $1,929,134 119,822 0.20% Shares
FMR LLC $1,917,735 119,114 0.19% Shares
Legal & General Group Plc $1,821,602 113,143 0.19% Shares
OP Asset Management Ltd $1,771,886 110,055 0.18% Shares
XTX Topco Ltd $1,728,770 107,377 0.18% Shares
WINTON GROUP Ltd $1,710,577 106,247 0.17% Shares
DCF Advisers, LLC $1,670,150 103,736 0.17% Shares
Essex LLC $1,588,442 98,661 0.16% Shares
Swiss National Bank $1,481,200 92,000 0.15% Shares
Quinn Opportunity Partners LLC $1,449,000 90,000 0.15% Shares
Erste Asset Management GmbH $1,438,320 92,200 0.15% Shares
VOLORIDGE INVESTMENT MANAGEMENT, LLC $1,299,850 80,736 0.13% Shares
PRUDENTIAL FINANCIAL INC $1,205,407 74,870 0.12% Shares
ALPS ADVISORS INC $1,201,801 74,646 0.12% Shares
ALLIANCEBERNSTEIN L.P. $1,179,347 97,790 0.12% Shares
TUDOR INVESTMENT CORP ET AL $1,173,964 72,917 0.12% Shares
Cubist Systematic Strategies, LLC $1,171,859 99,902 0.12% Shares
Point72 Asset Management, L.P. $1,152,309 71,572 0.12% Shares
BNP PARIBAS FINANCIAL MARKETS $1,130,880 70,241 0.11% Shares
TD Asset Management Inc $1,001,001 62,174 0.10% Shares
Man Group plc $939,918 58,380 0.10% Shares
TEMA ETFS LLC $925,597 60,457 0.09% Shares
MORGAN STANLEY $894,373 55,551 0.09% Shares
Rafferty Asset Management, LLC $868,112 53,920 0.09% Shares
Quantinno Capital Management LP $861,253 53,494 0.09% Shares
D. E. Shaw & Co., Inc. $812,648 50,475 0.08% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $800,106 49,696 0.08% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $714,888 44,403 0.07% Shares
MetLife Investment Management, LLC $653,885 40,614 0.07% Shares
CIBC Private Wealth Group LLC $616,564 52,563 0.06% Shares
Palumbo Wealth Management LLC $604,394 37,540 0.06% Shares
Cerity Partners LLC $570,149 35,413 0.06% Shares
EntryPoint Capital, LLC $527,307 32,752 0.05% Shares
Louisiana State Employees Retirement System $523,250 32,500 0.05% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $514,073 31,930 0.05% Shares
VANGUARD ASSET MANAGEMENT, Ltd $505,427 31,393 0.05% Shares
LPL Financial LLC $496,508 30,839 0.05% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $495,304 41,070 0.05% Shares
PROFUND ADVISORS LLC $476,818 29,616 0.05% Shares
State of Tennessee, Department of Treasury $472,745 29,363 0.05% Shares
Squarepoint Ops LLC $458,963 28,507 0.05% Shares
Invesco Ltd. $449,013 27,889 0.05% Shares
Vanguard Global Advisers, LLC $444,779 27,626 0.05% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $435,940 27,077 0.04% Shares
HighVista Strategies LLC $431,834 26,822 0.04% Shares
Virtus Investment Advisers, LLC $427,246 26,537 0.04% Shares
VANGUARD GROUP INC $422,954 27,626 0.04% Shares
Creative Planning $416,459 25,867 0.04% Shares
NEW YORK STATE COMMON RETIREMENT FUND $415,203 25,789 0.04% Shares
DIVERSIFIED TRUST CO $362,089 22,490 0.04% Shares
Mitsubishi UFJ Asset Management Co., Ltd. $352,284 21,881 0.04% Shares
Police & Firemen's Retirement System of New Jersey $333,721 20,728 0.03% Shares
AlphaQuest LLC $324,450 21,192 0.03% Shares
Lynx1 Capital Management LP $292,923 18,194 0.03% Shares
JANUS HENDERSON GROUP PLC $289,391 23,986 0.03% Shares
Brevan Howard Capital Management LP $285,163 17,712 0.03% Shares
Mariner, LLC $284,609 17,681 0.03% Shares
IEQ CAPITAL, LLC $284,036 17,642 0.03% Shares

Company insiders 28 insiders · 10 officers · 16 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Bassil I Dahiyat PRESIDENT & CEO March 10, 2025 S 465,419 0 0 $0
Bart Jan Cornelissen SR. VICE PRESIDENT & CFO April 10, 2025 S 61,348 0 0 $0
John J Kuch SR. VICE PRESIDENT & CFO March 11, 2024 S 121,070 0 0 $0
Nancy Valente EVP, Chief Development Officer May 2, 2025 S 49,169 0 0 $0
Celia Eckert SVP, GENERAL COUNSEL March 10, 2025 S 63,507 0 0 $0
John R Desjarlais SR. VICE PRESIDENT & CSO March 10, 2025 S 236,574 0 0 $0
Allen Yang SR. VICE PRESIDENT & CMO March 9, 2023 S 73,364 0 0 $0
Paul A Foster Chief Medical Officer Feb. 12, 2019 A 4,952 0 0 $0
Edgardo Baracchini Jr Chief Business Officer Aug. 13, 2018 M 207 0 0 $0
Lloyd A Rowland Sr. V.P. and General Counsel Jan. 26, 2016 A 1,501 0 0 $0
Raymond Joseph Deshaies Director June 16, 2026 A 10,302 0 0 $0
Ellen Feigal Director June 16, 2026 A 22,642 0 1 $-89,370
Barbara Klencke Director June 16, 2026 A 29,974 0 0 $0
Kurt A Gustafson Director June 16, 2026 A 25,011 0 1 $-67,385
Alan Bruce Montgomery Director June 16, 2026 A 25,849 0 1 $-62,338
Richard J Ranieri Director June 16, 2026 A 24,011 0 1 $-67,385
Todd E Simpson Director June 16, 2026 A 23,988 0 0 $0
Kevin Charles Gorman Director June 16, 2026 A 21,680 0 1 $-92,657
Dagmar Rosa-Bjorkeson Director Sept. 27, 2024 S 8,490 0 0 $0
Yujiro S Hata Director June 23, 2022 A 0 0 $0
Bruce L A Carter Director June 14, 2017 S 48,578 0 0 $0
Robert Baltera Jr. Director June 23, 2016 A 0 0 $0
Jonathan Fleming Director June 9, 2015 A 790,881 0 0 $0
Atul Saran Director Dec. 6, 2013 C 1,319,522 0 0 $0
Harold R Werner Director Dec. 6, 2013 C 1,035,407 0 0 $0
John S Stafford III 10% owner April 6, 2020 S 606,005 0 0 $0
Ronin Trading, LLC 10% owner Nov. 13, 2015 G 2,000,000 0 0 $0
John S Stafford JR 10% owner Dec. 6, 2013 C 2,000,443 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
John S. Stafford III (“Stafford”), Ronin Capital, LLC, Ronin Trading, LLC ×11 filings June 10, 2020 Initial filing SEC
John S. Stafford III Dec. 16, 2013 Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 56 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.87% 9,424 SH Aug. 8, 2026 Daily
PSCH · Invesco Exchange-Traded Fund Trust … 0.78% 64,345 SH Aug. 8, 2026 Daily
SBIO · ALPS ETF Trust 0.56% 75,597 NS May 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.53% 16,707 NS April 30, 2026 N-PORT
IDNA · iShares Trust 0.49% 48,671 SH Aug. 8, 2026 Daily
ESSC · Strategy Shares 0.21% 4,628 NS April 30, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.19% 81,350 NS April 30, 2026 N-PORT
IJS · iShares Trust 0.16% 663,144 SH Aug. 8, 2026 Daily
VIOV · VANGUARD ADMIRAL FUNDS 0.13% 157,324 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.11% 511,240 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.11% 4,035 SH Aug. 8, 2026 Daily
QVMS · Invesco Exchange-Traded Fund Trust … 0.09% 11,447 SH Aug. 8, 2026 Daily
XJR · iShares Trust 0.09% 8,742 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.09% 651,921 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.09% 120,287 SH Aug. 8, 2026 Daily
IJR · iShares Trust 0.08% 4,523,936 SH Aug. 8, 2026 Daily
SMLF · iShares Trust 0.07% 152,473 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.07% 59,668 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.07% 157,222 NS May 31, 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0.06% 258,479 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.04% 1,781,665 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.04% 2,711 NS May 31, 2026 N-PORT
ISCV · iShares Trust 0.04% 13,340 SH Aug. 8, 2026 Daily
SAA · ProShares Trust 0.04% 853 NS May 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.04% 22,818 NS April 30, 2026 N-PORT
SMDX · Tidal Trust III 0.03% 3,189 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.03% 400,570 SH Aug. 8, 2026 Daily
TECB · iShares Trust 0.03% 6,927 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.03% 30,542 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.02% 3,316 NS May 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.02% 243,932 NS April 30, 2026 N-PORT
ISCB · iShares Trust 0.02% 2,695 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.02% 339,994 NS May 31, 2026 N-PORT
UWM · ProShares Trust 0.01% 2,593 NS May 31, 2026 N-PORT
WSML · iShares Trust 0.01% 4,031 SH Aug. 8, 2026 Daily
RWJ · Invesco Exchange-Traded Fund Trust … 0.01% 10,428 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.01% 860,506 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 138,132 SH Aug. 8, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.01% 22,923 NS April 30, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.01% 3,045 NS April 30, 2026 N-PORT
URTY · ProShares Trust 0.01% 2,623 NS May 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 160,392 NS April 30, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.00% 36,139 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 2,434 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 66 NS May 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 8,021 NS April 30, 2026 N-PORT
AVSU · AMERICAN CENTURY ETF TRUST 0.00% 1,032 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 105,037 SH Aug. 8, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 19,815 NS April 30, 2026 N-PORT
IWV · iShares Trust 0.00% 15,186 SH Aug. 8, 2026 Daily