LEGN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $18.57
P/E -26.8
EPS $-0.81
Revenue $627M
ROE -29.1%
52W Range $16–$38

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10-Year Performance Revenue, net income, margins and EPS trends

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Revenue$627M
2018-12-31 → 2024-12-31
EPS$-0.81
2018-12-31 → 2025-12-31
Free Cash Flow$-129M
2020-12-31 → 2025-12-31
Net margin·
2020-12-31 → 2024-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend LEGN 5Y avg Peer Median Verdict
P/E -26.85Y avg ≈-40.8 ≈-40.8 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise -245.2%
Next Report Nov 10, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 11, 2026 $0.18 $0.08 135.6%
March 31, 2026 May 11, 2026 $-0.30 $-0.02 -1295.3%
Dec. 31, 2025 $-0.16 $-0.11 -44.5%
Sept. 30, 2025 $-0.22 $-0.09 -155.5%
June 30, 2025 $-0.68 $-0.15 -366.1%
March 31, 2025 $-0.54 $-0.23 -137.4%
Dec. 31, 2024 $0.15 $-0.32 147.1%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 14
Metric Trend 2025202420232022202120202019
Revenue ·$627M$285M$117M$69M$75M$60M
Cost of Revenue $397M$216M$144M$65M$0$0·
R&D Expense $415M$414M$382M$336M$313M$232M$162M
Operating Income $-136M$-310M$-528M····
Interest Expense $21M$22M$22M$11M$900.0K$4M$223.0K
Interest Income $40M$61M$54M$8M$971.0K$3M$5M
Pretax Income $-283M$-158M$-520M$-446M$-407M$-308M$-127M
Income Tax $14M$19M$-2M$625.0K$-4M$-42M$-26M
Net Income $-297M$-177M$-518M$-446M$-404M$-266M$-102M
EPS (Basic) $-0.81$-0.48$-1.47$-1.40$-1.43$-1.13$-0.51
EPS (Diluted) $-0.81$-0.48$-1.47$-1.40$-1.43$-1.13$-0.51
Shares (Basic) 368,641,170365,702,143352,165,418318,083,913281,703,291236,305,234200,000,000
Shares (Diluted) 368,641,170365,702,143352,165,418318,083,913···
EBITDA $-136M······
Balance Sheet 10
Metric Trend 2025202420232022202120202019
Cash & Equivalents $949M$1.13B$1.31B$841M$859M$506M$159M
Inventory $32M$24M$19M$10M$2M$2M$1M
Current Assets $1.25B$1.28B$1.50B$1.10B$950M$594M$207M
PP&E (Net) $116M$99M$109M$105M$103M$72M$45M
Intangibles $2M$2M$4M$3M$5M$3M$519.0K
Total Assets $1.73B$1.67B$1.85B$1.33B$1.12B$722M$288M
Current Liabilities $636M$278M$216M$298M$229M$116M$128M
Total Liabilities $732M$630M$597M$587M$354M$124M$411M
Retained Earnings ····$471M$280M$-123M
Stockholders' Equity $1.00B$1.04B$1.25B$744M$766M$598M$-123M
Cash Flow 6
Metric Trend 2025202420232022202120202019
Operating Cash Flow $-100M$-144M$-393M$-201M$-198M$-223M$-83M
CapEx $29M$14M$20M$21M$42M$26M$27M
Investing Cash Flow $710M$-851M$93M$-77M$-195M$-24M$-59M
Financing Cash Flow $-300.0K$6M$791M$378M$627M$619M$15M
Free Cash Flow $-129M$-158M$-413M$-222M$-241M$-269M·
Levered FCF $-151M$-182M$-435M$-233M$-242M$-273M·
Profitability 5
Metric Trend 2025202420232022202120202019
Net Margin ·-28.2%-181.8%-381.5%-586.4%-401.0%·
Pretax Margin ·-25.2%-182.4%-380.9%-591.6%-406.5%·
ROA -17.4%-10.1%-32.6%-36.4%-43.8%-59.9%·
ROE -29.1%-15.4%-51.9%-59.1%-59.2%-140.6%·
ROIC -14.3%······
Liquidity & Solvency 3
Metric Trend 2025202420232022202120202019
Current Ratio 2.04.66.93.74.13.7·
Quick Ratio 1.54.16.12.83.73.1·
Interest Coverage -6.4······
Efficiency 2
Metric Trend 2025202420232022202120202019
Asset Turnover ·0.40.20.10.10.1·
Inventory Turnover 14.210.09.710.8···
Per Share 3
Metric Trend 2025202420232022202120202019
Revenue / Share ·$1.72·····
Cash Flow / Share $-0.27$-0.39·····
EPS (TTM) $-0.81$-0.48$-1.47$-1.40$-1.43$-1.13·
Valuation (TTM) 4
Metric Trend 2025202420232022202120202019
Revenue TTM ·$627M$285M$117M$69M$75M·
Net Income TTM $-297M$-177M$-518M$-446M$-404M$-266M·
P/E -26.8-67.8-40.9-35.7-32.6-24.9·
Earnings Yield -3.7%-1.5%-2.4%-2.8%-3.1%-4.0%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue · $627M $285M $117M $69M
Net Income $-297M $-177M $-518M $-446M $-404M
Diluted EPS $-0.81 $-0.48 $-1.47 $-1.40 $-1.43

Institutional owners (13F) 236 filers · $3.0B total · As of Sept. 30, 2026

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Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 236
Value held $3.0B
New positions 57
Exited positions 25
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
57 (+23 vs prior Q) 25 (-14 vs prior Q) 67 (-15 vs prior Q) 79 (+23 vs prior Q) +6.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $840,231,809 29,093,899 28.04% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $235,014,985 8,137,638 7.84% Shares
MONTANOVA CAPITAL, LLC $204,181,600 7,070,000 6.81% Shares
HHLR ADVISORS, LTD. $172,833,804 5,984,550 5.77% Shares
BlackRock, Inc. $136,502,311 4,726,534 4.56% Shares
WESTFIELD CAPITAL MANAGEMENT CO LP $127,940,224 4,430,063 4.27% Shares
GOLDMAN SACHS GROUP INC $105,767,658 3,662,315 3.53% Shares
Point72 Asset Management, L.P. $88,838,461 3,076,124 2.96% Shares
Kynam Capital Management, LP $86,674,800 3,001,205 2.89% Shares
Assenagon Asset Management S.A. $55,306,817 1,915,056 1.85% Shares
Artisan Partners Limited Partnership $45,036,656 1,559,441 1.50% Shares
STATE STREET CORP $43,291,671 1,498,704 1.44% Shares
Capital International Investors $41,028,488 1,420,654 1.37% Shares
MORGAN STANLEY $40,274,080 1,394,531 1.34% Shares
Soleus Capital Management, L.P. $34,800,400 1,205,000 1.16% Shares
Davern Capital Partners, LP $34,411,155 1,191,522 1.15% Shares
Driehaus Capital Management LLC $33,466,375 1,158,808 1.12% Shares
RENAISSANCE TECHNOLOGIES LLC $28,885,776 1,000,200 0.96% Shares
Ghisallo Capital Management LLC $28,880,000 1,000,000 0.96% Shares
MATTHEWS INTERNATIONAL CAPITAL MANAGEMENT LLC $26,490,642 917,266 0.88% Shares
JOHNSON & JOHNSON $23,525,244 814,586 0.79% Shares
IvyRock Asset Management (HK) Ltd $23,132,880 801,000 0.77% Shares
EcoR1 Capital, LLC $23,104,000 800,000 0.77% Shares
JPMORGAN CHASE & CO $22,523,437 766,364 0.75% Shares
Squarepoint Ops LLC $22,215,998 769,252 0.74% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $21,948,627 759,994 0.73% Shares
Woodline Partners LP $19,149,924 663,086 0.64% Shares
Triata Capital Ltd $18,191,916 629,914 0.61% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $17,328,000 600,000 0.58% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $16,596,903 574,685 0.55% Shares
Elmind Capital, LP $16,478,033 570,569 0.55% Shares
GEODE CAPITAL MANAGEMENT, LLC $16,157,962 563,489 0.54% Shares
TWO SIGMA ADVISERS, LP $14,991,904 689,600 0.50% Shares
Candriam S.C.A. $14,568,175 504,924 0.49% Shares
UBS Group AG $14,511,218 502,466 0.48% Shares
CenterBook Partners LP $13,079,954 452,907 0.44% Shares
ArrowMark Colorado Holdings LLC $10,477,115 362,781 0.35% Shares
Hudson Bay Capital Management LP $9,819,200 340,000 0.33% Shares
Alyeska Investment Group, L.P. $8,879,849 307,474 0.30% Shares
Empire Life Investments Inc. $8,565,404 296,586 0.29% Shares
NORTHERN TRUST CORP $7,937,842 274,856 0.26% Shares
Resolute Capital Asset Partners LLC $7,533,954 260,871 0.25% Shares
BNP PARIBAS FINANCIAL MARKETS $7,261,847 251,449 0.24% Shares
Burkehill Global Management, LP $7,220,000 250,000 0.24% Shares
AMERIPRISE FINANCIAL INC $7,213,272 249,767 0.24% Shares
Invesco Ltd. $7,159,409 247,902 0.24% Shares
HSBC HOLDINGS PLC $6,820,611 236,204 0.23% Shares
Legal & General Group Plc $6,580,800 227,867 0.22% Shares
Longaeva Partners L.P. $6,190,572 214,355 0.21% Shares
Balyasny Asset Management L.P. $6,093,564 210,996 0.20% Shares

Show all 236 institutional owners →

Company insiders 10 insiders · 4 officers · 7 directors

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Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Ingrid Zhang Chief Executive Officer Sept. 15, 2026 A 1,131,860 0 0 $0
Alan Bash Interim CEO Aug. 14, 2026 A 35,142 0 0 $0
Ying Huang Chief Executive Officer June 30, 2026 G 238,490 0 2 $-169,404
Carlos E Santos Chief Financial Officer Sept. 21, 2026 S 14,246 0 1 $-49,630
Corazon (Corsee) D. Sanders Director Sept. 29, 2026 S 52,731 0 1 $-258,920
Li Mao Director Sept. 24, 2026 A 65,316 0 0 $0
Peter Salovey Director Sept. 24, 2026 A 55,096 0 0 $0
Patrick John Casey Director Sept. 24, 2026 A 69,590 0 1 $-88,800
Darren Xiaohui Ji Director Sept. 24, 2026 A 92,103 0 0 $0
Tomas J. Heyman Director Sept. 24, 2026 A 53,720 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 17 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PBE · Invesco Exchange-Traded Fund Trust 2.58% 550,910 SH Oct. 1, 2026 Daily
MEDI · Harbor ETF Trust 1.91% 42,415 NS July 31, 2026 N-PORT
BBP · ETFis Series Trust I 0.71% 37,834 NS July 31, 2026 N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr… 0.31% 1,539 NS July 31, 2026 N-PORT
IBB · iShares Trust 0.21% 1,132,518 SH Sept. 11, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.12% 6,507 SH Oct. 1, 2026 Daily
ESIM · Strategy Shares 0.07% 655 NS July 31, 2026 N-PORT
MCHI · iShares Trust 0.06% 185,824 SH Sept. 11, 2026 Daily
BKF · iShares, Inc. 0.03% 1,184 SH Sept. 11, 2026 Daily
EEMA · iShares, Inc. 0.02% 10,243 SH Sept. 11, 2026 Daily
FBCG · FIDELITY COVINGTON TRUST 0.02% 68,015 NS July 31, 2026 N-PORT
AAXJ · iShares Trust 0.01% 29,070 SH Sept. 11, 2026 Daily
EEM · iShares, Inc. 0.01% 186,106 SH Sept. 11, 2026 Daily
IEMG · iShares, Inc. 0.01% 839,899 SH Sept. 11, 2026 Daily
ACWX · iShares Trust 0.00% 24,903 SH Sept. 11, 2026 Daily
IXUS · iShares Trust 0.00% 118,403 SH Sept. 11, 2026 Daily
ACWI · iShares Trust 0.00% 18,110 SH Sept. 11, 2026 Daily

LEGN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

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rating · 23 analysts BUY
Median target $48.00 +158.5%
6 26.1% Strong Buy
11 47.8% Buy
6 26.1% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

13 analysts · 2026-10-02

Mean target $46.50 +150.4%

← Below all targets Current price $18.57
Low$24.00 Mean$46.50 High$74.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

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FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
LEGN · -26.8 · · -29.1% ·
RLAY $1.47B -5.3 53.4% -1800.6% -44.9% ·
TNGX $1.20B -10.2 48.3% -162.8% -42.2% ·
VKTX $4.04B -11.0 · · -47.3% ·
VCYT $3.34B 51.3 16.0% 12.8% 5.2% 70.1%
IDYA $3.04B -27.0 3024.4% -52.0% -11.5% ·
PBLS · · · · · ·
CELC $4.81B -26.3 · · -244.3% ·
CDNA $959M -47.1 13.8% -5.6% -6.8% ·

Latest News Recent headlines mentioning this company

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My Metrics Your personal watchlist — selected rows from Full Fundamentals

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Source: SEC 20-F filed Mar 10, 2026