ACHV — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $49 724 879 | 7 614 836 | 9,06% | Actions |
| TPG GP A, LLC | $44 910 597 | 6 877 580 | 8,19% | Actions |
| venBio Partners LLC | $38 623 122 | 5 914 720 | 7,04% | Actions |
| Logos Global Management LP | $35 425 250 | 5 425 000 | 6,46% | Actions |
| BlackRock, Inc. | $34 426 271 | 5 272 017 | 6,28% | Actions |
| FRANKLIN RESOURCES INC | $32 344 527 | 4 953 220 | 5,90% | Actions |
| Paradigm Biocapital Advisors LP | $32 335 620 | 4 951 856 | 5,89% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $27 039 502 | 4 140 812 | 4,93% | Actions |
| Propel Bio Management, LLC | $26 342 138 | 4 034 018 | 4,80% | Actions |
| MARSHALL WACE, LLP | $24 620 145 | 3 770 313 | 4,49% | Actions |
| STATE STREET CORP | $19 234 285 | 2 945 526 | 3,51% | Actions |
| Venrock Adviser, LLC | $17 964 239 | 2 751 032 | 3,27% | Actions |
| Vivo Capital, LLC | $17 964 239 | 2 751 032 | 3,27% | Actions |
| EVENTIDE ASSET MANAGEMENT, LLC | $14 496 600 | 2 220 000 | 2,64% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $13 471 818 | 2 062 721 | 2,46% | Actions |
| Alyeska Investment Group, L.P. | $12 574 965 | 1 925 722 | 2,29% | Actions |
| VANGUARD GROUP INC | $12 297 331 | 2 474 312 | 2,24% | Actions |
| Simplify Asset Management Inc. | $9 351 646 | 1 432 105 | 1,70% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $9 317 755 | 1 426 915 | 1,70% | Actions |
| Caption Management, LLC | $7 676 015 | 1 175 500 | 1,40% | Option d'achat |
| LPL Financial LLC | $5 891 725 | 902 255 | 1,07% | Actions |
| NORTHERN TRUST CORP | $4 856 753 | 743 760 | 0,89% | Actions |
| Spruce Street Capital LP | $4 810 240 | 736 637 | 0,88% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $3 877 194 | 593 751 | 0,71% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 771 075 | 577 500 | 0,69% | Option d'achat |
| RAYMOND JAMES FINANCIAL INC | $3 567 457 | 546 318 | 0,65% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3 510 502 | 537 596 | 0,64% | Actions |
| KVP Capital Advisors, LP | $3 019 178 | 462 355 | 0,55% | Actions |
| TWO SIGMA INVESTMENTS, LP | $2 880 951 | 441 187 | 0,53% | Actions |
| UBS Group AG | $2 043 916 | 313 004 | 0,37% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 515 861 | 232 138 | 0,28% | Actions |
| Caption Management, LLC | $1 487 096 | 227 733 | 0,27% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1 483 472 | 227 178 | 0,27% | Actions |
| Bank of New York Mellon Corp | $1 424 364 | 218 126 | 0,26% | Actions |
| JANE STREET GROUP, LLC | $1 331 467 | 203 900 | 0,24% | Option d'achat |
| CITADEL ADVISORS LLC | $1 326 243 | 203 100 | 0,24% | Option d'achat |
| Nuveen, LLC | $1 248 210 | 191 150 | 0,23% | Actions |
| BANK OF AMERICA CORP /DE/ | $1 208 540 | 185 075 | 0,22% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $1 162 660 | 178 049 | 0,21% | Actions |
| WELLS FARGO & COMPANY/MN | $1 114 233 | 170 633 | 0,20% | Actions |
| TWO SIGMA ADVISERS, LP | $1 043 203 | 209 900 | 0,19% | Actions |
| CITADEL ADVISORS LLC | $804 032 | 123 129 | 0,15% | Actions |
| CANTOR FITZGERALD, L. P. | $794 250 | 121 631 | 0,14% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $791 534 | 121 215 | 0,14% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $677 161 | 103 700 | 0,12% | Option de vente |
| Shay Capital LLC | $606 049 | 92 810 | 0,11% | Actions |
| XTX Topco Ltd | $587 896 | 90 030 | 0,11% | Actions |
| RHUMBLINE ADVISERS | $568 253 | 87 023 | 0,10% | Actions |
| Blue Trust, Inc. | $560 849 | 85 888 | 0,10% | Actions |
| Diametric Capital, LP | $530 098 | 81 179 | 0,10% | Actions |
| DEUTSCHE BANK AG\ | $505 977 | 77 485 | 0,09% | Actions |
| CITIGROUP INC | $483 965 | 74 114 | 0,09% | Actions |
| MANCHESTER FINANCIAL INC | $438 666 | 67 177 | 0,08% | Actions |
| MEMBERS WEALTH LLC | $435 962 | 66 763 | 0,08% | Actions |
| MORGAN STANLEY | $387 713 | 59 374 | 0,07% | Actions |
| Virtus Investment Advisers, LLC | $387 066 | 59 275 | 0,07% | Actions |
| ADAR1 Capital Management, LLC | $351 314 | 53 800 | 0,06% | Actions |
| JANE STREET GROUP, LLC | $329 478 | 50 456 | 0,06% | Actions |
| MetLife Investment Management, LLC | $300 282 | 45 985 | 0,05% | Actions |
| OSAIC HOLDINGS, INC. | $281 540 | 43 115 | 0,05% | Actions |
| WINTON GROUP Ltd | $277 525 | 42 500 | 0,05% | Actions |
| Invesco Ltd. | $276 167 | 42 292 | 0,05% | Actions |
| GOLDMAN SACHS GROUP INC | $267 573 | 40 976 | 0,05% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $260 219 | 40 050 | 0,05% | Actions |
| Rafferty Asset Management, LLC | $245 012 | 37 521 | 0,04% | Actions |
| Next Capital Management LLC | $228 517 | 34 995 | 0,04% | Actions |
| AMERIFLEX GROUP, INC. | $219 395 | 33 598 | 0,04% | Actions |
| Vanguard Global Advisers, LLC | $211 624 | 32 408 | 0,04% | Actions |
| JPMORGAN CHASE & CO | $201 160 | 32 289 | 0,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $198 329 | 30 372 | 0,04% | Actions |
| Rockefeller Capital Management L.P. | $195 900 | 30 000 | 0,04% | Actions |
| Jones Hill Capital LP | $174 743 | 26 760 | 0,03% | Actions |
| BCV Asset Management Inc. | $164 591 | 26 365 | 0,03% | Actions |
| AXQ CAPITAL, LP | $164 380 | 25 173 | 0,03% | Actions |
| Robertson Stephens Wealth Management, LLC | $163 250 | 25 000 | 0,03% | Actions |
| Keating Financial Advisory Services, Inc. | $162 669 | 24 911 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $149 916 | 22 958 | 0,03% | Actions |
| ALLIANCEBERNSTEIN L.P. | $143 884 | 48 940 | 0,03% | Actions |
| Scientech Research LLC | $143 706 | 22 007 | 0,03% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $134 583 | 20 610 | 0,02% | Actions |
| SEI INVESTMENTS CO | $133 865 | 20 500 | 0,02% | Actions |
| BARCLAYS PLC | $130 561 | 19 994 | 0,02% | Actions |
| PROFUND ADVISORS LLC | $129 660 | 19 856 | 0,02% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $125 376 | 19 200 | 0,02% | Actions |
| nVerses Capital, LLC | $118 852 | 18 201 | 0,02% | Actions |
| FMR LLC | $115 628 | 17 707 | 0,02% | Actions |
| Cubist Systematic Strategies, LLC | $111 898 | 35 523 | 0,02% | Actions |
| MAGNOLIA CAPITAL ADVISORS LLC | $98 603 | 15 100 | 0,02% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $96 931 | 14 844 | 0,02% | Actions |
| SBI Securities Co., Ltd. | $96 912 | 14 841 | 0,02% | Actions |
| INTECH INVESTMENT MANAGEMENT LLC | $89 696 | 13 736 | 0,02% | Actions |
| StoneX Group Inc. | $86 507 | 16 342 | 0,02% | Actions |
| PRUDENTIAL FINANCIAL INC | $85 151 | 13 040 | 0,02% | Actions |
| Alpine Global Management, LLC | $81 625 | 12 500 | 0,01% | Actions |
| ROYAL BANK OF CANADA | $81 000 | 12 376 | 0,01% | Actions |
| Windsor Capital Management, LLC | $70 635 | 10 817 | 0,01% | Actions |
| ProShare Advisors LLC | $66 554 | 10 192 | 0,01% | Actions |
| Legal & General Group Plc | $49 334 | 7 555 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $46 128 | 7 064 | 0,01% | Actions |
| Russell Investments Group, Ltd. | $41 622 | 6 374 | 0,01% | Actions |
| Point72 Asia (Singapore) Pte. Ltd. | $23 641 | 7 505 | 0,00% | Actions |
| Allworth Financial LP | $19 590 | 3 000 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $19 551 | 2 994 | 0,00% | Actions |
| Persistent Asset Partners Ltd | $18 153 | 2 780 | 0,00% | Actions |
| Steward Partners Investment Advisory, LLC | $15 881 | 2 432 | 0,00% | Actions |
| FIFTH THIRD BANCORP | $14 954 | 2 290 | 0,00% | Actions |
| Federation des caisses Desjardins du Quebec | $13 060 | 2 000 | 0,00% | Actions |
| COMERICA BANK | $11 839 | 2 382 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $7 000 | 1 072 | 0,00% | Actions |
| CWM, LLC | $5 004 | 1 702 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $4 826 | 739 | 0,00% | Actions |
| SITTNER & NELSON, LLC | $4 395 | 673 | 0,00% | Actions |
| JONES FINANCIAL COMPANIES LLLP | $1 806 | 300 | 0,00% | Actions |
| Sterling Capital Management LLC | $1 783 | 273 | 0,00% | Actions |
| Versant Capital Management, Inc | $1 715 | 212 | 0,00% | Actions |
| Point72 (DIFC) Ltd | $595 | 189 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $423 | 64 769 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $131 | 20 | 0,00% | Actions |
| Arax Advisory Partners | $65 | 10 | 0,00% | Actions |
| Optiver Holding B.V. | $13 | 2 | 0,00% | Actions |
| Capital Analysts, LLC | $5 | 700 | 0,00% | Actions |
| Pacer Advisors, Inc. | $4 | 627 | 0,00% | Actions |
| Avion Wealth | $3 | 500 | 0,00% | Actions |