RYTM Rhythm Pharmaceuticals, Inc. - Common Stock
$117,52
Prix · Aoû 19, 2026
Données fondamentales au Aoû 4, 2026
Fourchette 52 semaines
$74–$122
90% of range
Note des analystes
BUY
22 analysts
Objectif de cours
$142
+20% upside
P/E (TTM)
-37.8
ROE
-309.1%
Marge nette
-103.6%
À propos de Rhythm Pharmaceuticals, Inc. - Common Stock Présentation de l'entreprise depuis Wikipedia
RYTM Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$117.52
Capitalisation Boursière
$7.90B
P/E (TTM)
-37.8
BPA (TTM)
$-3.11
Revenus (TTM)
$190M
Rendement div.
—
ROE
-309.1%
Dette/Capitaux propres
0.8
Fourchette 52 semaines
$75 – $122
RYTM Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
$190M
2016-12-31
→
2025-12-31
BPA
$-3.11
2019-12-31
→
2025-12-31
Flux de trésorerie libre
$-117M
2017-12-31
→
2025-12-31
Marges
-103.6%
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
RYTM
Médiane des pairs
P/E (TTM)
-37.8
16.0
P/S (TTM)
41.6
47.5
P/B
56.8
8.5
EV / EBITDA
-39.8
—
Price / FCF (Cours / FCF)
-67.7
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
RYTM
Médiane des pairs
Operating Margin (Marge d'exploitation)
-101.2%
—
Net Profit Margin (Marge nette)
-103.6%
-140.2%
ROA
-45.1%
-45.0%
ROE
-309.1%
-86.5%
ROIC
-77.9%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
RYTM
Médiane des pairs
Debt / Equity (Dette / Capitaux propres)
0.8
0.0
Current Ratio (Ratio de liquidité)
4.4
5.8
Quick Ratio (Ratio de liquidité réduite)
3.9
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
RYTM
Médiane des pairs
Revenue YoY (Chiffre d'affaires YoY)
45.8%
—
Revenue CAGR 3Y (CAGR du chiffre d'affaires 3 ans)
100.2%
—
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
RYTM
Médiane des pairs
RYTM Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
22 analystes
- Achat fort 8 36,4%
- Achat 12 54,5%
- Conserver 2 9,1%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
15 analystes · 2026-08-18
Médiane
$145.00
Maintenant
$117.52
Bas
$105.00
Haut
$160.00
Objectif médian
$145.00
+23,4%
Objectif moyen
$141.53
+20,4%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
0.00%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.73 | $-0.84 | 0.11% |
| 31 mars 2026 | $-0.83 | $-0.87 | 0.04% |
| 31 décembre 2025 | $-0.73 | $-0.84 | 0.11% |
| 30 septembre 2025 | $-0.82 | $-0.74 | -0.08% |
| 30 juin 2025 | $-0.75 | $-0.69 | -0.06% |
| 31 mars 2025 | $-0.81 | $-0.72 | -0.09% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| RYTM | $7.19B | -34.4 | 45.8% | -103.6% | -309.1% | — |
| IMVT | $5.07B | -9.0 | 229.2% | — | -73.7% | — |
| IBRX | $2.00B | -5.2 | 668.3% | -310.2% | 71.0% | — |
| TWST | $1.71B | -21.6 | 20.3% | -20.6% | -17.0% | — |
| TGTX | $4.63B | 10.8 | 87.3% | 72.6% | 96.7% | — |
| ORKA | $1.48B | -3.3 | — | — | -25.9% | — |
| CGON | $3.35B | -20.0 | 254.7% | -3985.0% | -22.6% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 17
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $190M | $130M | $77M | $24M | $3M | $0 | $0 | $0 | $0 | $0 | |
| Cost of Revenue | $19M | $13M | $9M | $2M | $599.0K | · | · | · | · | · | |
| R&D Expense | $167M | $238M | $135M | $109M | $104M | $90M | $109M | $50M | $23M | $20M | |
| SG&A Expense | $195M | $144M | $118M | $92M | $68M | $46M | $37M | $28M | $10M | $6M | |
| Operating Expenses | $382M | $396M | $262M | $203M | $173M | $137M | $146M | $78M | $32M | $26M | |
| Operating Income | $-192M | $-266M | $-184M | $-179M | $-170M | $-137M | $-146M | $-78M | $-32M | $-26M | |
| Interest Expense | · | · | $14M | $5M | · | · | · | · | · | · | |
| Interest Income | · | · | · | · | $447.0K | $3M | $5M | $4M | $566.0K | $33.0K | |
| Other Non-op | $1M | $2M | $190.0K | $-790.0K | $100M | $3M | $5M | $4M | $-1M | $33.0K | |
| Pretax Income | $-196M | $-260M | $-184M | $-181M | $-70M | · | · | · | · | · | |
| Income Tax | $497.0K | $346.0K | $564.0K | · | · | · | · | · | · | · | |
| Net Income | $-197M | $-261M | $-185M | $-181M | $-70M | $-134M | $-141M | $-74M | $-34M | $-26M | |
| EPS (Basic) | $-3.11 | $-4.34 | $-3.20 | $-3.47 | $-1.40 | $-3.04 | $-3.86 | · | · | · | |
| EPS (Diluted) | $-3.11 | $-4.34 | $-3.20 | $-3.47 | $-1.40 | $-3.04 | $-3.86 | · | · | · | |
| Shares (Basic) | 64,984,361 | 60,995,204 | 57,673,128 | 52,120,701 | 49,600,294 | 44,127,220 | 36,422,450 | · | · | · | |
| Shares (Diluted) | 64,984,361 | 60,995,204 | 57,673,128 | 52,120,701 | 49,600,294 | 44,127,220 | 36,422,450 | · | · | · | |
| EBITDA | $-192M | $-265M | $-183M | $-178M | $-169M | $-136M | $-145M | $-78M | $-32M | · |
Bilan 27
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $54M | $89M | $60M | $128M | $59M | $101M | $62M | $50M | $34M | $7M | |
| Short-term Investments | $335M | $231M | $216M | $206M | $236M | $72M | $230M | · | $114M | $4M | |
| Receivables | $26M | $19M | $15M | $6M | $1M | · | · | · | · | · | |
| Inventory | $26M | $19M | $9M | $3M | $111.0K | · | · | · | · | · | |
| Prepaid Expense | $26M | $16M | $9M | $12M | $12M | $9M | $10M | $7M | $3M | $638.0K | |
| Other Current Assets | $10M | $9M | $7M | $7M | $4M | $3M | $4M | $1M | $1M | $216.0K | |
| Current Assets | $467M | $374M | $308M | $354M | $308M | $182M | $302M | $259M | $151M | $11M | |
| PP&E (Net) | $1M | $632.0K | $1M | $2M | $3M | $3M | $4M | $1M | $840.0K | $930.0K | |
| PP&E (Gross) | $6M | $5M | $5M | $5M | $5M | $5M | $4M | $2M | $1M | $1M | |
| Accum. Depreciation | $5M | $5M | $4M | $3M | $2M | $1M | $752.0K | $809.0K | $367.0K | $144.0K | |
| Intangibles | $5M | $6M | $7M | $8M | $5M | · | · | · | · | · | |
| Other Non-current Assets | $3M | $7M | $15M | $17M | · | · | · | · | · | · | |
| Total Assets | $480M | $392M | $333M | $382M | $330M | $187M | $309M | $260M | $152M | $12M | |
| Accounts Payable | $14M | $12M | $5M | $5M | $6M | $5M | $10M | $8M | $2M | $2M | |
| Accrued Liabilities | $84M | $63M | $48M | $33M | $30M | $13M | $14M | $6M | $4M | $3M | |
| Current Liabilities | $106M | $116M | $55M | $40M | $43M | $18M | $24M | $14M | $7M | $5M | |
| Capital Leases | $3M | $4M | $490.0K | $1M | $2M | · | · | · | · | · | |
| Total Liabilities | $210M | $228M | $163M | $118M | $45M | $21M | $28M | $14M | $7M | $5M | |
| Long-term Debt | $108M | $110M | · | · | · | · | · | · | · | · | |
| Total Debt | $108M | $110M | · | · | · | · | · | · | · | · | |
| Common Stock | $67.0K | $61.0K | $59.0K | $56.0K | $50.0K | $44.0K | $44.0K | $34.0K | $27.0K | $10.0K | |
| Paid-in Capital | $1.49B | $1.18B | $1.06B | $974M | $813M | $626M | $606M | $431M | $255M | $44M | |
| Retained Earnings | $-1.35B | $-1.16B | $-895M | $-710M | $-529M | $-459M | $-325M | $-185M | $-110M | $-77M | |
| AOCI | $-796.0K | $-39.0K | $134.0K | $-92.0K | $-1.0K | $49.0K | · | · | · | · | |
| Stockholders' Equity | $139M | $22M | $170M | $264M | $284M | $167M | $281M | $246M | $145M | $-33M | |
| Liabilities + Equity | $480M | $392M | $333M | $382M | $330M | $187M | $309M | $260M | $152M | $12M | |
| Shares Outstanding | 67,205,321 | 62,390,654 | 59,426,559 | 56,612,429 | 50,283,574 | 44,235,903 | 43,996,753 | 34,410,725 | 27,284,140 | 10,196,292 |
Flux de trésorerie 16
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $500.0K | $700.0K | $900.0K | $896.0K | $816.0K | $690.0K | $834.0K | $442.0K | $223.0K | $144.0K | |
| Stock-based Comp | $67M | $40M | $33M | $20M | $21M | $17M | $12M | $6M | $2M | $1M | |
| Deferred Tax | $0 | $0 | $0 | · | · | · | · | $0 | $0 | $0 | |
| Amort. of Intangibles | · | · | $855.0K | $774.0K | $342.0K | · | · | · | · | · | |
| Other Non-cash | $14M | $106M | $15M | $-13M | $-98M | $-6M | $5M | $5M | $2M | · | |
| Operating Cash Flow | $-116M | $-114M | $-136M | $-173M | $-146M | $-122M | $-123M | $-62M | $-29M | $-23M | |
| CapEx | $953.0K | $0 | $47.0K | $281.0K | $434.0K | $214.0K | $3M | $722.0K | $133.0K | $1M | |
| Investing Cash Flow | $-137M | $-48M | $-6M | $28M | $-62M | $159M | $-28M | $-87M | $-110M | $-5M | |
| Debt Issued | $0 | $0 | $24M | $72M | · | · | · | · | · | · | |
| Net Debt Issued | $-20M | $-13M | $17M | $72M | · | · | · | · | · | · | |
| Stock Issued | $34M | $39M | $49M | $131M | $162M | · | $161M | $163M | $126M | · | |
| Net Stock Activity | $34M | $39M | $49M | $131M | $162M | · | $161M | $163M | $126M | · | |
| Financing Cash Flow | $218M | $191M | $74M | $214M | $166M | $2M | $163M | $165M | $167M | · | |
| Net Change in Cash | $-35M | $29M | $-68M | $68M | $-42M | $39M | $13M | $15M | $28M | $-28M | |
| Free Cash Flow | $-117M | · | $-136M | $-174M | $-146M | $-122M | $-126M | $-63M | $-30M | · | |
| Levered FCF | · | · | $-150M | · | · | · | · | · | · | · |
Rentabilité 7
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -101.2% | -204.0% | -238.1% | -757.9% | -5391.9% | · | · | · | · | · | |
| Net Margin | -103.6% | -200.3% | -238.5% | -766.2% | -2207.1% | · | · | · | · | · | |
| Pretax Margin | -103.3% | -200.0% | -237.8% | · | · | · | · | · | · | · | |
| EBITDA Margin | -100.9% | -203.5% | -236.9% | -754.1% | -5366.0% | · | · | · | · | · | |
| ROA | -45.1% | -71.9% | -51.6% | -50.9% | -27.0% | -54.1% | -49.5% | -36.0% | -41.1% | · | |
| ROE | -309.1% | -1582.1% | -100.6% | -66.4% | -23.0% | -73.7% | -65.4% | -28.7% | -60.2% | · | |
| ROIC | -77.9% | -202.1% | -108.9% | · | · | · | · | · | · | · |
Liquidité et Solvabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 4.4 | 3.2 | 5.6 | 8.9 | 7.1 | 10.1 | 12.4 | 19.0 | 22.4 | · | |
| Quick Ratio | 3.9 | 2.9 | 5.3 | 8.5 | 6.8 | 9.6 | 2.6 | 3.6 | 22.0 | · | |
| Debt / Equity | 0.8 | 5.1 | · | · | · | · | · | · | · | · | |
| LT Debt / Equity | 0.7 | 5.0 | · | · | · | · | · | · | · | · | |
| Interest Coverage | · | · | -13.3 | -34.4 | · | · | · | · | · | · |
Efficacité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.4 | 0.4 | 0.2 | 0.1 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | · | |
| Inventory Turnover | 0.9 | 1.0 | 1.6 | 1.4 | 10.8 | · | · | · | · | · | |
| Receivables Turnover | 8.5 | 7.8 | 7.3 | 6.5 | 6.2 | · | · | · | · | · |
Taux de croissance 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 45.8% | 68.1% | 227.6% | 649.5% | · | · | · | · | · | · | |
| Revenue CAGR 3Y | 100.2% | 245.5% | · | · | · | · | · | · | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $190M | $130M | $77M | $24M | $3M | $0 | $0 | $0 | $0 | · | |
| Net Income TTM | $-197M | $-261M | $-185M | $-181M | $-70M | $-134M | $-141M | $-74M | $-34M | · | |
| Market Cap | $7.19B | $3.49B | $2.73B | $1.65B | $502M | $1.32B | $1.01B | $925M | $793M | · | |
| Enterprise Value | $6.91B | $3.28B | · | · | · | · | · | · | · | · | |
| P/E | -34.4 | -12.9 | -14.4 | -8.4 | -7.1 | -9.8 | -5.9 | · | · | · | |
| P/S | 37.9 | 26.8 | 35.3 | 69.7 | 159.1 | · | · | · | · | · | |
| P/B | 51.7 | 160.7 | 16.1 | 6.2 | 1.8 | 7.9 | 3.6 | 3.8 | 5.5 | · | |
| P / Tangible Book | 53.8 | 224.5 | 16.8 | 6.4 | 1.8 | 7.9 | · | · | · | · | |
| P / Cash Flow | -62.2 | -30.7 | -20.1 | -9.5 | -3.4 | -10.8 | -8.2 | -14.9 | -26.9 | · | |
| P / FCF | -61.7 | · | -20.1 | -9.5 | -3.4 | -10.8 | -8.0 | -14.7 | -26.8 | · | |
| EV / EBITDA | -36.1 | -12.4 | · | · | · | · | · | · | · | · | |
| EV / FCF | -59.3 | · | · | · | · | · | · | · | · | · | |
| EV / Revenue | 36.4 | 25.2 | · | · | · | · | · | · | · | · | |
| Earnings Yield | -2.9% | -7.8% | -7.0% | -11.9% | -14.0% | -10.2% | -16.8% | · | · | · |
Compte de résultat 16
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $71M | $60M | $57M | $51M | $49M | $33M | $42M | $33M | $29M | $26M | $24M | $23M | $19M | $11M | $9M | $4M | |
| Cost of Revenue | $9M | $7M | $5M | $5M | $6M | $4M | $4M | $4M | $3M | $3M | $3M | $2M | $2M | $1M | $1M | $497.0K | |
| R&D Expense | $43M | $42M | $42M | $46M | $42M | $37M | $41M | $38M | $30M | $129M | $30M | $34M | $34M | $38M | $24M | $21M | |
| SG&A Expense | $67M | $64M | $57M | $52M | $46M | $39M | $38M | $35M | $36M | $34M | $32M | $30M | $30M | $25M | $26M | $22M | |
| Operating Expenses | $120M | $112M | $104M | $104M | $94M | $80M | $83M | $77M | $70M | $166M | $66M | $66M | $66M | $64M | $51M | $44M | |
| Operating Income | $-49M | $-52M | $-47M | $-53M | $-45M | $-47M | $-41M | $-44M | $-40M | $-140M | $-41M | $-44M | $-47M | $-53M | $-42M | $-39M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $5M | · | $3M | $3M | $3M | · | $2M | |
| Other Non-op | $1M | $-2M | $58.0K | $274.0K | $2M | $-644.0K | $325.0K | $1M | $302.0K | $524.0K | $393.0K | $-159.0K | $-17.0K | $-27.0K | $-54.0K | $-370.0K | |
| Pretax Income | $-49M | $-55M | $-48M | $-53M | $-46M | $-49M | $-43M | $-44M | $-32M | $-141M | $-41M | $-44M | $-47M | $-52M | $-42M | $-41M | |
| Income Tax | $444.0K | $545.0K | $-31.0K | $111.0K | $337.0K | $80.0K | $-89.0K | $-344.0K | $479.0K | $300.0K | $196.0K | $368.0K | $0 | $0 | · | · | |
| Net Income | $-49M | $-56M | $-48M | $-53M | $-47M | $-49M | $-43M | $-44M | $-32M | $-141M | $-42M | $-44M | $-47M | $-52M | $-42M | $-41M | |
| EPS (Basic) | $-0.73 | $-0.83 | $-0.73 | $-0.82 | $-0.75 | $-0.81 | $-0.71 | $-0.73 | $-0.55 | $-2.35 | $-0.70 | $-0.76 | $-0.82 | $-0.92 | $-0.74 | $-0.79 | |
| EPS (Diluted) | $-0.73 | $-0.83 | $-0.73 | $-0.82 | $-0.75 | $-0.81 | $-0.71 | $-0.73 | $-0.55 | $-2.35 | $-0.70 | $-0.76 | $-0.82 | $-0.92 | · | $-0.79 | |
| Shares (Basic) | 68,592,661 | 67,974,193 | -128,020,218 | 66,261,055 | 63,684,359 | 63,059,165 | -121,380,096 | 61,219,918 | 61,011,824 | 60,143,558 | -113,778,469 | 57,874,960 | 56,867,662 | 56,708,975 | -100,004,851 | 51,400,922 | |
| Shares (Diluted) | 68,592,661 | 67,974,193 | -128,020,218 | 66,261,055 | 63,684,359 | 63,059,165 | -121,380,096 | 61,219,918 | 61,011,824 | 60,143,558 | -113,778,469 | 57,874,960 | 56,867,662 | 56,708,975 | · | 51,400,922 | |
| EBITDA | $-49M | $-52M | · | $-53M | $-45M | $-47M | · | $-44M | · | $-140M | · | $-44M | $-47M | $-53M | · | $-39M |
Bilan 28
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $66M | $62M | $54M | $52M | $136M | $106M | $89M | $48M | $162M | $53M | · | $65M | $116M | $110M | · | $185M | |
| Short-term Investments | $265M | $278M | $335M | $364M | $155M | $208M | $231M | $251M | $157M | $148M | · | $235M | $138M | $185M | · | $163M | |
| Receivables | $40M | $34M | $26M | $33M | $26M | $18M | $19M | $19M | $18M | $15M | · | $15M | $14M | $8M | · | $3M | |
| Inventory | $31M | $29M | $26M | $22M | $19M | $19M | $19M | $14M | $12M | $9M | · | $8M | $6M | $5M | · | · | |
| Prepaid Expense | $25M | $27M | $26M | $24M | $25M | $18M | $16M | $9M | $9M | $11M | · | $8M | $10M | $10M | · | $11M | |
| Other Current Assets | · | · | $10M | · | · | · | $9M | · | · | · | · | · | · | · | · | · | |
| Current Assets | $427M | $430M | $467M | $495M | $361M | $369M | $374M | $340M | $357M | $236M | · | $329M | $284M | $318M | · | $362M | |
| PP&E (Net) | $103.0K | $1M | $1M | $237.0K | $297.0K | $462.0K | $632.0K | $801.0K | $973.0K | $1M | · | $2M | $2M | $2M | · | $2M | |
| PP&E (Gross) | · | · | $6M | · | · | · | $5M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $5M | · | · | · | $5M | · | · | · | · | · | · | · | · | · | |
| Intangibles | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | $7M | $7M | · | $7M | $7M | $8M | · | $8M | |
| Other Non-current Assets | · | · | $3M | · | · | · | $7M | · | · | · | · | · | · | · | · | · | |
| Total Assets | $437M | $442M | $480M | $507M | $373M | $387M | $392M | $364M | $382M | $259M | · | $354M | $310M | $346M | · | $390M | |
| Accounts Payable | $16M | $12M | $14M | $14M | $16M | $12M | $12M | $5M | $5M | $8M | · | $4M | $8M | $13M | · | $5M | |
| Accrued Liabilities | · | · | $84M | · | · | $59M | $63M | $55M | $48M | $45M | · | $44M | $36M | $31M | · | $26M | |
| Current Liabilities | $124M | $103M | $106M | $104M | $129M | $112M | $116M | $98M | $55M | $54M | · | $50M | $46M | $46M | · | $33M | |
| Capital Leases | $3M | $3M | $3M | $4M | $4M | $4M | $4M | $4M | $3M | $284.0K | · | $692.0K | $888.0K | $1M | · | $1M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | $36M | $35M | · | · | · | · | · | · | |
| Total Liabilities | $220M | $205M | $210M | $211M | $239M | $224M | $228M | $211M | $202M | $197M | · | $157M | $128M | $126M | · | $108M | |
| Long-term Debt | $106M | $108M | $108M | $109M | $110M | $110M | $110M | · | · | · | · | · | · | · | · | $73M | |
| Total Debt | $106M | $108M | · | $109M | $110M | $110M | · | · | · | · | · | · | · | · | · | · | |
| Common Stock | $69.0K | $69.0K | $67.0K | $67.0K | $64.0K | $62.0K | $61.0K | $61.0K | $60.0K | $60.0K | · | $59.0K | $57.0K | $56.0K | · | $56.0K | |
| Paid-in Capital | $1.56B | $1.53B | $1.49B | $1.45B | $1.24B | $1.22B | $1.18B | $1.12B | $1.11B | $1.10B | · | $1.05B | $991M | $982M | · | $949M | |
| Retained Earnings | $-1.46B | $-1.41B | $-1.35B | $-1.30B | $-1.25B | $-1.20B | $-1.16B | $-1.11B | $-1.07B | $-1.04B | · | $-853M | $-809M | $-762M | · | $-668M | |
| AOCI | $-912.0K | $444.0K | $-796.0K | $-926.0K | $-2M | $-51.0K | $-39.0K | $-604.0K | $-617.0K | $-181.0K | · | $-113.0K | $-14.0K | $-6.0K | · | $-339.0K | |
| Stockholders' Equity | $103M | $123M | $139M | $149M | $-12M | $19M | $22M | $11M | $39M | $62M | $170M | $197M | $182M | $220M | $264M | $281M | |
| Liabilities + Equity | $437M | $442M | $480M | $507M | $373M | $387M | $392M | $364M | $382M | $259M | · | $354M | $310M | $346M | · | $390M | |
| Shares Outstanding | 68,816,868 | 68,445,084 | 67,205,321 | 66,684,077 | 63,913,185 | 63,494,892 | 62,390,654 | 61,436,251 | 61,095,949 | 60,964,468 | · | 59,089,352 | 56,896,068 | 56,852,404 | · | 55,756,256 |
Flux de trésorerie 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $26M | $23M | $19M | $19M | $16M | $13M | $11M | $11M | $10M | $8M | $9M | $9M | $9M | $6M | $5M | $5M | |
| Amort. of Intangibles | · | · | · | · | · | · | · | · | · | · | · | · | · | $214.0K | · | $214.0K | |
| Operating Cash Flow | $-9M | $-44M | $-25M | $-27M | $-23M | $-40M | $-19M | $-25M | $-29M | $-41M | $-29M | $-29M | $-41M | $-36M | $-34M | $-47M | |
| CapEx | · | · | · | · | · | · | · | · | · | · | $-1.0K | $1.0K | $0 | $47.0K | $-1.0K | $95.0K | |
| Investing Cash Flow | $14M | $57M | $30M | $-246M | $54M | $25M | $21M | $-91M | $-9M | $30M | $23M | $-95M | $48M | $18M | $-41M | $-40M | |
| Debt Issued | · | · | · | · | · | · | · | · | · | · | $0 | · | · | · | $-3M | $38M | |
| Net Debt Issued | · | $-4M | · | · | · | $-5M | · | · | · | $-3M | · | · | · | $-1M | · | · | |
| Stock Issued | $0 | $0 | · | · | $0 | $34M | · | · | · | · | $0 | · | · | · | $14M | · | |
| Net Stock Activity | · | $0 | · | · | · | $34M | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $-1M | $-5M | $-3M | $189M | $-889.0K | $32M | $38M | $2M | $146M | $4M | $2M | $73M | $-965.0K | $-133.0K | $17M | $159M | |
| Net Change in Cash | $3M | $8M | $2M | $-83M | $30M | $17M | $42M | $-114M | $108M | $-7M | $-5M | $-51M | $6M | $-18M | $-57M | $72M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | · | · | · | · | $-36M | · | · |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -68.1% | -87.1% | · | -102.6% | -93.4% | -143.7% | · | -132.0% | · | -538.7% | · | -195.3% | -242.5% | -458.0% | · | · | |
| Net Margin | -69.2% | -92.6% | · | -103.1% | -96.1% | -151.3% | · | -131.2% | · | -544.4% | · | -196.2% | -243.0% | -455.0% | · | · | |
| Pretax Margin | -68.6% | -91.6% | · | -102.9% | -95.5% | -151.1% | · | -132.3% | · | -543.3% | · | -194.6% | · | · | · | · | |
| EBITDA Margin | -68.1% | -87.1% | · | -102.6% | -93.4% | -143.7% | · | -132.0% | · | -538.7% | · | -195.3% | -242.5% | -458.0% | · | · | |
| ROA | -12.2% | -13.4% | · | -12.2% | -12.4% | -15.3% | · | -12.2% | · | -46.8% | · | -11.9% | -15.9% | -16.6% | · | -11.0% | |
| ROE | -108.3% | -78.5% | · | -66.1% | -340.0% | -122.9% | · | -41.8% | · | -100.5% | · | -18.4% | -24.7% | -22.9% | · | -13.5% | |
| ROIC | -23.4% | -22.9% | · | -20.5% | -46.6% | -36.6% | · | -388.2% | · | -227.6% | · | -22.4% | · | · | · | · |
Liquidité et Solvabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.5 | 4.2 | · | 4.7 | 2.8 | 3.3 | · | 3.5 | · | 4.4 | · | 6.6 | 6.2 | 6.9 | · | 10.9 | |
| Quick Ratio | 3.0 | 3.6 | · | 4.3 | 2.4 | 3.0 | · | 3.3 | · | 4.0 | · | 6.3 | 5.8 | 6.6 | · | 10.6 | |
| Debt / Equity | 1.0 | 0.9 | · | 0.7 | -9.2 | 5.8 | · | · | · | · | · | · | · | · | · | · | |
| LT Debt / Equity | 0.9 | 0.8 | · | 0.7 | -8.9 | 5.7 | · | · | · | · | · | · | · | · | · | · | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -29.4 | · | -14.0 | -14.1 | -17.2 | · | -18.3 |
Efficacité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | · | 0.1 | · | 0.1 | 0.1 | 0.0 | · | · | |
| Inventory Turnover | 0.4 | 0.3 | · | 0.3 | 0.4 | 0.3 | · | 0.4 | · | 0.4 | · | 0.6 | 0.7 | 0.5 | · | · | |
| Receivables Turnover | 2.1 | 2.3 | · | 2.0 | 2.2 | 2.0 | · | 2.0 | · | 2.3 | · | 2.5 | 2.5 | 2.6 | · | · |
Valorisation (TTM) 13
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $231M | $193M | · | $166M | $144M | $121M | · | $111M | $97M | $79M | · | $57M | $44M | $26M | · | $16M | |
| Net Income TTM | $-204M | $-205M | · | $-193M | $-172M | $-267M | · | $-261M | $-264M | $-284M | · | $-184M | $-185M | $-191M | · | $-174M | |
| Market Cap | $7.64B | $5.95B | · | $6.73B | $4.04B | $3.36B | · | $3.22B | · | $2.64B | · | $1.35B | $938M | $1.01B | · | $1.37B | |
| Enterprise Value | $7.42B | $5.72B | · | $6.43B | $3.86B | $3.16B | · | · | · | · | · | · | · | · | · | · | |
| P/E | -35.5 | -27.1 | · | -32.5 | -22.2 | -11.9 | · | -11.9 | -9.2 | -8.9 | · | -7.0 | -4.8 | -4.9 | · | -7.1 | |
| P/S | 33.1 | 30.9 | · | 40.6 | 28.1 | 27.8 | · | 29.0 | · | 33.4 | · | 23.6 | 21.3 | 38.5 | · | 86.0 | |
| P/B | 74.2 | 48.4 | · | 45.3 | -339.2 | 177.5 | · | 287.0 | · | 42.9 | · | 6.9 | 5.1 | 4.6 | · | 4.9 | |
| P / Tangible Book | 77.9 | 50.5 | · | 47.0 | · | 259.0 | · | 666.8 | 76.6 | 48.2 | · | 7.1 | 5.4 | 4.8 | · | 5.0 | |
| P / Cash Flow | · | -134.7 | · | · | · | -83.4 | · | · | · | -64.8 | · | · | · | -27.8 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -27.8 | · | · | |
| EV / EBITDA | -152.7 | -109.3 | · | -122.1 | -85.2 | -67.2 | · | · | · | · | · | · | · | · | · | · | |
| EV / Revenue | 32.1 | 29.7 | · | 38.8 | 26.9 | 26.1 | · | · | · | · | · | · | · | · | · | · | |
| Earnings Yield | -2.8% | -3.7% | · | -3.1% | -4.5% | -8.4% | · | -8.4% | -10.9% | -11.2% | · | -14.3% | -20.7% | -20.5% | · | -14.0% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $190M | $130M | $77M | $24M | $3M |
| Marge d'exploitation % | -101.2% | -204.0% | -238.1% | -757.9% | -5391.9% |
| Résultat net | $-197M | $-261M | $-185M | $-181M | $-70M |
| BPA dilué | $-3.11 | $-4.34 | $-3.20 | $-3.47 | $-1.40 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Dette / Capitaux propres | 0.8 | 5.1 | — | — | — |
| Ratio de liquidité | 4.4 | 3.2 | 5.6 | 8.9 | 7.1 |
| Ratio de liquidité réduite | 3.9 | 2.9 | 5.3 | 8.5 | 6.8 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-117M | — | $-136M | $-174M | $-146M |
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Détenteurs institutionnels (13F) 320 déclarants · $7.0B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 64 (+5 vs T. préc.) | 38 (-8 vs T. préc.) | 99 (-4 vs T. préc.) | 94 (+10 vs T. préc.) | +9.2M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $740 218 912 | 6 666 837 | 10,63% | Actions |
| BAKER BROS. ADVISORS LP | $622 265 747 | 5 604 483 | 8,94% | Actions |
| VANGUARD GROUP INC | $612 335 379 | 5 720 622 | 8,80% | Actions |
| PRIMECAP MANAGEMENT CO/CA/ | $351 837 748 | 3 168 853 | 5,05% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $348 289 452 | 3 136 895 | 5,00% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $333 753 626 | 3 005 977 | 4,79% | Actions |
| PERCEPTIVE ADVISORS LLC | $287 156 334 | 2 586 295 | 4,13% | Actions |
| STATE STREET CORP | $285 728 722 | 2 573 529 | 4,10% | Actions |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $245 220 303 | 2 208 595 | 3,52% | Actions |
| Polar Capital Holdings Plc | $184 713 061 | 1 663 632 | 2,65% | Actions |
| GOLDMAN SACHS GROUP INC | $181 683 274 | 1 636 344 | 2,61% | Actions |
| Capital Research Global Investors | $170 131 602 | 1 532 303 | 2,44% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $145 911 779 | 1 313 860 | 2,10% | Actions |
| CITADEL ADVISORS LLC | $140 303 282 | 1 263 652 | 2,02% | Actions |
| Checkpoint Capital L.P. | $131 681 580 | 1 186 000 | 1,89% | Actions |
| Siren, L.L.C. | $126 160 613 | 1 136 275 | 1,81% | Actions |
| Pictet Asset Management Holding SA | $106 252 095 | 957 785 | 1,53% | Actions |
| MORGAN STANLEY | $94 763 217 | 853 492 | 1,36% | Actions |
| FMR LLC | $89 815 609 | 808 931 | 1,29% | Actions |
| Woodline Partners LP | $84 259 668 | 758 891 | 1,21% | Actions |
| ALLIANCEBERNSTEIN L.P. | $77 814 059 | 894 723 | 1,12% | Actions |
| Clearbridge Investments, LLC | $77 329 368 | 696 473 | 1,11% | Actions |
| Rock Springs Capital Management LP | $76 899 156 | 692 598 | 1,10% | Actions |
| NORGES BANK | $76 149 259 | 685 844 | 1,09% | Actions |
| Integral Health Asset Management, LLC | $61 066 500 | 550 000 | 0,88% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $49 488 625 | 445 723 | 0,71% | Actions |
| Candriam S.C.A. | $48 032 508 | 433 025 | 0,69% | Actions |
| Squarepoint Ops LLC | $46 956 919 | 422 921 | 0,67% | Actions |
| Point72 Asset Management, L.P. | $45 989 736 | 414 210 | 0,66% | Actions |
| Sofinnova Investments, Inc. | $45 303 238 | 408 027 | 0,65% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $44 078 910 | 397 000 | 0,63% | Actions |
| BRAIDWELL LP | $42 316 642 | 381 128 | 0,61% | Actions |
| LOOMIS SAYLES & CO L P | $40 081 941 | 361 001 | 0,58% | Actions |
| Artisan Partners Limited Partnership | $39 395 220 | 354 816 | 0,57% | Actions |
| AMERIPRISE FINANCIAL INC | $38 809 678 | 349 540 | 0,56% | Actions |
| ORBIMED ADVISORS LLC | $35 851 587 | 322 900 | 0,52% | Actions |
| MILLENNIUM MANAGEMENT LLC | $35 165 311 | 316 719 | 0,51% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $35 155 873 | 316 634 | 0,51% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $34 581 515 | 311 461 | 0,50% | Actions |
| Capital World Investors | $24 587 594 | 221 450 | 0,35% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $21 914 435 | 197 374 | 0,31% | Actions |
| KENNEDY CAPITAL MANAGEMENT LLC | $21 452 661 | 193 215 | 0,31% | Actions |
| Assenagon Asset Management S.A. | $20 706 096 | 186 491 | 0,30% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $17 616 744 | 160 094 | 0,25% | Actions |
| First Turn Management, LLC | $17 100 619 | 154 018 | 0,25% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $16 449 317 | 148 152 | 0,24% | Actions |
| BANK OF AMERICA CORP /DE/ | $16 099 572 | 145 002 | 0,23% | Actions |
| Nicholas Investment Partners, LP | $15 463 148 | 139 270 | 0,22% | Actions |
| ADAR1 Capital Management, LLC | $15 117 623 | 136 158 | 0,22% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $15 085 313 | 135 867 | 0,22% | Actions |
| Qube Research & Technologies Ltd | $14 923 542 | 134 410 | 0,21% | Actions |
| NEXTBio Capital Management LP | $14 629 091 | 131 758 | 0,21% | Actions |
| BlackRock, Inc. | $14 611 659 | 131 601 | 0,21% | Actions |
| Driehaus Capital Management LLC | $14 354 514 | 129 285 | 0,21% | Actions |
| SummitTX Capital, L.P. | $14 034 303 | 126 401 | 0,20% | Actions |
| Logos Global Management LP | $13 878 750 | 125 000 | 0,20% | Actions |
| Opaleye Management Inc. | $13 601 175 | 122 500 | 0,20% | Actions |
| SEGALL BRYANT & HAMILL, LLC | $13 530 782 | 121 866 | 0,19% | Actions |
| Longaeva Partners L.P. | $12 221 516 | 110 074 | 0,18% | Actions |
| Swiss National Bank | $12 179 991 | 109 700 | 0,17% | Actions |
| PFM Health Sciences, LP | $11 275 097 | 101 550 | 0,16% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $10 991 970 | 99 000 | 0,16% | Option d'achat |
| Aberdeen Group plc | $10 541 854 | 94 946 | 0,15% | Actions |
| AXIOM INVESTORS LLC /DE | $9 646 286 | 86 880 | 0,14% | Actions |
| First Light Asset Management, LLC | $9 522 488 | 85 765 | 0,14% | Actions |
| ALGERT GLOBAL LLC | $9 263 344 | 83 431 | 0,13% | Actions |
| Granahan Investment Management, LLC | $9 245 468 | 83 270 | 0,13% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $8 926 812 | 80 400 | 0,13% | Actions |
| WCM INVESTMENT MANAGEMENT, LLC | $8 863 942 | 80 552 | 0,13% | Actions |
| Atom Investors LP | $8 156 819 | 73 465 | 0,12% | Actions |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $8 153 155 | 73 432 | 0,12% | Actions |
| RHUMBLINE ADVISERS | $8 142 147 | 73 333 | 0,12% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $7 610 884 | 68 548 | 0,11% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $7 581 239 | 68 281 | 0,11% | Actions |
| PICTON MAHONEY ASSET MANAGEMENT | $7 314 658 | 65 880 | 0,11% | Actions |
| Blue Owl Capital Holdings LP | $6 823 349 | 61 455 | 0,10% | Actions |
| ExodusPoint Capital Management, LP | $6 789 151 | 61 147 | 0,10% | Actions |
| PRUDENTIAL FINANCIAL INC | $6 444 736 | 58 045 | 0,09% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $6 347 585 | 57 170 | 0,09% | Actions |
| Trexquant Investment LP | $6 245 215 | 56 248 | 0,09% | Actions |
| NEUBERGER BERMAN GROUP LLC | $6 210 463 | 55 935 | 0,09% | Actions |
| CITIGROUP INC | $6 124 526 | 55 161 | 0,09% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $5 915 567 | 53 279 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $5 842 843 | 52 624 | 0,08% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5 723 148 | 65 806 | 0,08% | Actions |
| Nan Fung Group Holdings Ltd | $5 453 794 | 49 120 | 0,08% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $5 384 622 | 48 497 | 0,08% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 362 749 | 48 300 | 0,08% | Option de vente |
| CANADA PENSION PLAN INVESTMENT BOARD | $5 262 822 | 47 400 | 0,08% | Actions |
| Hillsdale Investment Management Inc. | $4 885 320 | 44 000 | 0,07% | Actions |
| Cinctive Capital Management LP | $4 745 311 | 42 739 | 0,07% | Actions |
| Zweig-DiMenna Associates LLC | $4 674 363 | 42 100 | 0,07% | Actions |
| TD Asset Management Inc | $4 305 521 | 38 778 | 0,06% | Actions |
| EFG International AG | $3 726 164 | 33 563 | 0,05% | Actions |
| FIRST TRUST ADVISORS LP | $3 606 476 | 32 482 | 0,05% | Actions |
| Exome Asset Management LLC | $3 576 165 | 32 209 | 0,05% | Actions |
| Rafferty Asset Management, LLC | $3 575 943 | 32 207 | 0,05% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $3 573 945 | 32 189 | 0,05% | Actions |
| MetLife Investment Management, LLC | $3 564 507 | 32 104 | 0,05% | Actions |
| Schonfeld Strategic Advisors LLC | $3 176 234 | 28 607 | 0,05% | Actions |
Initiés de la société 36 initiés · 12 dirigeants · 12 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| David P Meeker | President and CEO | 11 février 2026 A | 239 016 | 0 | 0 | $0 |
| Keith Michael Gottesdiener | CEO & President | 9 mars 2020 M | 558 250 | 0 | 0 | $0 |
| Hunter C Smith | Chief Financial Officer | 18 mai 2026 M | 119 611 | 0 | 23 | $-2 217 136 |
| Manher Joshi | Chief Medical Officer | 17 août 2026 A | — | 0 | 0 | $0 |
| Christopher Paul German | Corporate Controller & CAO | 15 mai 2026 M | 0 | 0 | 2 | $-930 921 |
| Pamela J. Cramer | Chief Human Resources Officer | 11 février 2026 A | 29 376 | 0 | 4 | $-2 987 366 |
| William T. Roberts | Chief Accounting Officer | 29 mars 2023 M | 7 872 | 0 | 0 | $0 |
| Linda Shapiro Manning | Chief Medical Officer | 9 février 2022 A | — | 0 | 0 | $0 |
| Murray Stewart | Chief Medical Officer | 11 février 2021 A | — | 0 | 0 | $0 |
| Nithya Desikan | Chief Commercial Officer | 31 août 2020 M | 43 602 | 0 | 0 | $0 |
| Leonardus H.T. Van Der Ploeg | Chief Scientific Officer | 31 mai 2019 M | 42 339 | 0 | 0 | $0 |
| Fred T. Fiedorek | Chief Medical Officer | 14 février 2018 A | — | 0 | 0 | $0 |
| Lynn A. Tetrault | Administrateur | 24 juin 2026 A | 11 712 | 0 | 1 | $-3 711 840 |
| Stuart A Arbuckle | Administrateur | 24 juin 2026 A | 11 712 | 0 | 0 | $0 |
| Christophe Jean | Administrateur | 24 juin 2026 A | 11 712 | 0 | 0 | $0 |
| Jennifer L Good | Administrateur | 24 juin 2026 A | 11 712 | 0 | 0 | $0 |
| David W J Mcgirr | Administrateur | 24 juin 2026 A | 11 712 | 0 | 0 | $0 |
| Kimberly J Popovits | Administrateur | 1 avril 2026 A | — | 0 | 0 | $0 |
| Edward T. Mathers | Administrateur | 12 mars 2026 J | 14 168 | 0 | 0 | $0 |
| Camille L Bedrosian | Administrateur | 24 juin 2025 A | 7 000 | 0 | 0 | $0 |
| Todd Foley | Administrateur | 15 mars 2021 S | 909 258 | 0 | 0 | $0 |
| Neil Exter | Administrateur | 6 juin 2018 A | 0 | 0 | 0 | $0 |
| Hadley Harbor Master Investors (Cayman) L.P. | Détenteur de 10% | 10 octobre 2017 C | 545 256 | 0 | 0 | $0 |
| Ravi Viswanathan | Détenteur de 10% | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
| Ipsen, S.A. | Détenteur de 10% | 10 octobre 2017 C | 833 099 | 0 | 0 | $0 |
| Forest Baskett | Détenteur de 10% | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
| Patrick J. Kerins | Détenteur de 10% | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
| David M Mott | Détenteur de 10% | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
| James M Barrett | Détenteur de 10% | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
| Peter J Barris | Détenteur de 10% | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
| Alastair Garfield | — | 13 août 2026 S | 2 295 | 0 | 4 | $-912 697 |
| Joseph Shulman | — | 13 août 2026 M | 15 915 | 0 | 8 | $-5 858 835 |
| Jennifer Chien | — | 13 août 2026 M | 0 | 0 | 1 | $-8 901 395 |
| Yann Mazabraud | — | 12 août 2026 M | 55 655 | 0 | 6 | $-6 620 591 |
| Simon Kelner | — | 11 février 2021 A | — | 0 | 0 | $0 |
| Scott D. Sandell | — | 10 octobre 2017 C | 4 909 956 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 7 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| 30 avril 2024 | — | Dépôt initial | — | SEC | |
| Perceptive Advisors LLC, Perceptive Life Sciences Master Fund, Ltd., C2 Life Sciences LLC, Perceptive Discovery Fund LP, Joseph Edelman ×3 dépôts | 17 avril 2024 | — | Dépôt initial | — | SEC |
| New Enterprise Associates 13, L.P., NEA Partners 13, L.P., NEA 13 GP, LTD, Forest Baskett, Patrick J. Kerins, Scott D. Sandell ×2 dépôts | 29 mars 2023 | — | Dépôt initial | Investissement passif | SEC |
| MPM BioVentures V, L.P., MPM Asset Management Investors BV5 LLC, MPM BioVentures V GP LLC, MPM BioVentures V LLC, Ansbert Gadicke, Luke Evnin, Todd Foley ×2 dépôts | 26 juin 2020 | — | Dépôt initial | — | SEC |
| Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée | 5 février 2020 | — | Dépôt initial | — | SEC |
| Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée, Personne déclarante non divulguée | 12 février 2019 | — | Dépôt initial | — | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP V LLC ×5 dépôts | 10 août 2018 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 52 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| MEDI · Harbor ETF Trust | 3,79% | 12 831 NS | 30 avril 2026 | N-PORT |
| HAPS · Harbor ETF Trust | 1,58% | 30 540 NS | 30 avril 2026 | N-PORT |
| BBP · ETFis Series Trust I | 1,14% | 8 333 NS | 30 avril 2026 | N-PORT |
| GURU · Global X Funds | 0,88% | 6 307 NS | 30 avril 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,85% | 53 930 NS | 30 avril 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 0,68% | 1 538 NS | 31 mai 2026 | N-PORT |
| IBB · iShares Trust | 0,57% | 487 129 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,54% | 3 734 SH | 8 août 2026 | Quotidien |
| GSC · Goldman Sachs ETF Trust | 0,51% | 14 505 NS | 31 mai 2026 | N-PORT |
| IWO · iShares Trust | 0,38% | 500 174 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,36% | 59 038 SH | 8 août 2026 | Quotidien |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,36% | 30 730 NS | 31 mai 2026 | N-PORT |
| BIB · ProShares Trust | 0,30% | 2 526 NS | 31 mai 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0,30% | 9 299 NS | 31 mai 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,25% | 15 768 NS | 30 avril 2026 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0,24% | 2 335 NS | 30 avril 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,22% | 20 187 NS | 30 avril 2026 | N-PORT |
| VBK · VANGUARD INDEX FUNDS | 0,21% | 908 106 SH | 8 août 2026 | Quotidien |
| IWM · iShares Trust | 0,19% | 1 396 950 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,19% | 317 548 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,19% | 16 599 SH | 8 août 2026 | Quotidien |
| FFSM · FIDELITY COVINGTON TRUST | 0,16% | 25 413 NS | 30 avril 2026 | N-PORT |
| RSSL · Global X Funds | 0,13% | 22 978 NS | 30 avril 2026 | N-PORT |
| SMLF · iShares Trust | 0,13% | 49 347 SH | 8 août 2026 | Quotidien |
| ITWO · ProShares Trust | 0,12% | 2 491 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,11% | 292 435 NS | 31 mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,09% | 2 368 SH | 8 août 2026 | Quotidien |
| VB · VANGUARD INDEX FUNDS | 0,09% | 1 571 929 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,09% | 164 403 SH | 8 août 2026 | Quotidien |
| VXF · VANGUARD INDEX FUNDS | 0,08% | 715 506 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,07% | 26 169 NS | 30 avril 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,07% | 4 339 NS | 30 avril 2026 | N-PORT |
| UWM · ProShares Trust | 0,07% | 1 948 NS | 31 mai 2026 | N-PORT |
| ESML · iShares Trust | 0,07% | 17 482 SH | 8 août 2026 | Quotidien |
| GSSC · Goldman Sachs ETF Trust | 0,06% | 7 134 NS | 31 mai 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,06% | 10 436 NS | 30 avril 2026 | N-PORT |
| WSML · iShares Trust | 0,06% | 3 421 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,05% | 1 974 NS | 31 mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,05% | 12 161 SH | 8 août 2026 | Quotidien |
| HDG · ProShares Trust | 0,02% | 49 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 16 766 NS | 31 mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,01% | 2 916 NS | 30 avril 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,01% | 2 177 236 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,01% | 4 502 SH | 8 août 2026 | Quotidien |
| ESGV · VANGUARD WORLD FUND | 0,01% | 12 173 SH | 8 août 2026 | Quotidien |
| ITOT · iShares Trust | 0,01% | 83 947 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,01% | 14 047 SH | 8 août 2026 | Quotidien |
| SCHK · SCHWAB STRATEGIC TRUST | 0,01% | 4 991 NS | 31 mai 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,01% | 35 572 NS | 31 mai 2026 | N-PORT |
| AVUQ · AMERICAN CENTURY ETF TRUST | 0,00% | 24 NS | 31 mai 2026 | N-PORT |